CN103960669A - Glucosamine health product capable of increasing bone nutrition and improving bone mineral density and preparation method of glucosamine health product - Google Patents
Glucosamine health product capable of increasing bone nutrition and improving bone mineral density and preparation method of glucosamine health product Download PDFInfo
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- CN103960669A CN103960669A CN201410221898.5A CN201410221898A CN103960669A CN 103960669 A CN103960669 A CN 103960669A CN 201410221898 A CN201410221898 A CN 201410221898A CN 103960669 A CN103960669 A CN 103960669A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 43
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 26
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 24
- 230000035764 nutrition Effects 0.000 title claims abstract description 24
- 229910052500 inorganic mineral Inorganic materials 0.000 title abstract description 4
- 239000011707 mineral Substances 0.000 title abstract description 4
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 title abstract 8
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 title abstract 8
- 229960002442 glucosamine Drugs 0.000 title abstract 8
- 239000002775 capsule Substances 0.000 claims abstract description 50
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 26
- 238000000034 method Methods 0.000 claims abstract description 14
- 229920001287 Chondroitin sulfate Polymers 0.000 claims abstract description 13
- 102000008186 Collagen Human genes 0.000 claims abstract description 13
- 108010035532 Collagen Proteins 0.000 claims abstract description 13
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 13
- 229920001436 collagen Polymers 0.000 claims abstract description 13
- 238000005498 polishing Methods 0.000 claims abstract description 9
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229940059329 chondroitin sulfate Drugs 0.000 claims abstract description 7
- 238000002156 mixing Methods 0.000 claims abstract description 6
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 70
- 239000000203 mixture Substances 0.000 claims description 67
- 229910021529 ammonia Inorganic materials 0.000 claims description 35
- 230000037182 bone density Effects 0.000 claims description 17
- YCHKFNUDARWTSK-FRWAFGSFSA-M potassium;(3r,4r,5s,6r)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol;sulfuric acid;chloride Chemical compound [Cl-].[K+].OS(O)(=O)=O.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O YCHKFNUDARWTSK-FRWAFGSFSA-M 0.000 claims description 12
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 9
- 230000003749 cleanliness Effects 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 5
- 239000002994 raw material Substances 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 5
- 238000011049 filling Methods 0.000 abstract description 4
- 235000013402 health food Nutrition 0.000 abstract description 4
- 239000002245 particle Substances 0.000 abstract description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 208000010392 Bone Fractures Diseases 0.000 abstract 1
- 206010017076 Fracture Diseases 0.000 abstract 1
- 230000003848 cartilage regeneration Effects 0.000 abstract 1
- FGAMKHCTXLHFAL-FRWAFGSFSA-L dipotassium (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O FGAMKHCTXLHFAL-FRWAFGSFSA-L 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 238000009776 industrial production Methods 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 230000011164 ossification Effects 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 229940107200 chondroitin sulfates Drugs 0.000 description 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 210000000845 cartilage Anatomy 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 231100000957 no side effect Toxicity 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 230000001172 regenerating effect Effects 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 208000001132 Osteoporosis Diseases 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 229960003563 calcium carbonate Drugs 0.000 description 2
- 235000010755 mineral Nutrition 0.000 description 2
- 230000032683 aging Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention relates to a glucosamine health product capable of increasing bone nutrition and improving bone mineral density and a preparation method of the glucosamine health product, belonging to the technical field of health foods. The glucosamine health product consists of D-glucosamine potassium sulfate, chondroitin sulfate, calcium carbonate, bone collagen and magnesium stearate. The glucosamine health product can promote new bone formation and fracture healing, provide enough nutrition and promote cartilage regeneration. The method for preparing the glucosamine health product comprises the following steps: crushing individual raw materials by considering the factors such as powder raw materials and small particle size difference, screening, mixing, filling and polishing the raw materials to prepare the finished capsules. A granulation process with humid and hot factors is not adopted in the preparation process, and the process flow in which the product is instable is avoided as much as possible. The glucosamine health product is scientific in formula and reliable in effect and does not have toxic or side effect to a human body, the preparation method is mature and stable, and large-scale industrial production can be performed.
Description
Technical field
The present invention relates to ammonia sugar health products that can increase skeleton nutrition and improve bone density and preparation method thereof, belong to health food technology field.
Background technology
Along with the arrival of aging society, increasing the elderly will be faced with along with a series of health problems that the age increases, calcium loss increase brings, and its result is mainly that Decrease of Bone Mineral Density causes osteoporosis.Therefore, for this situation exploitation safety and reliable in function, to prevent and to slow down the Decrease of Bone Mineral Density that Age-related bone calcium loss causes, thereby prevention and reduce osteoporosis and occur as main purpose health functional food has objective social demand.
A kind of ammonia sugar health products that can increase skeleton nutrition and raising bone density that the present invention relates to are the health foods made from D-Glucosamine sulfate potassium chloride, chondroitin sulfate, calcium carbonate, bone collagen primary raw material, have the health care that increases bone density.The ammonia sugar health products that the present invention relates to will be filled in lighttight capsule damp and hot unsettled supplementary material, can prevent airborne oxygen, the impact of light on content, improve stability; And capsule outward appearance is bright and clean, attractive in appearance, can cover the uncomfortable taste of medicine; The synergy that these ammonia sugar health products make full use of each component is theoretical, improves product nutrition balance, and these ammonia sugar health products can promote new bone to form and union, and enough nutrition is provided, and promote regenerating bone or cartilage.The factors such as it is Powdered that the preparation method of this ammonia sugar health products considers that raw material is, and particle size differences is little, pulverize indivedual raw materials, then by raw material sieve, mix, the step such as filling, polishing makes finished capsule product.In this preparation method, do not adopt and have granulating process wet, hot factor, to avoid as far as possible causing the unsettled technical process of product.Scientific formulation, the reliable effect of this ammonia sugar health products, human body is had no side effect, preparation method is mature and stable, can industrial-scale production.
Summary of the invention
The present invention is achieved through the following technical solutions:
The ammonia sugar health products that can increase skeleton nutrition and raising bone density, its component is by weight: D-Glucosamine sulfate potassium chloride 220-280 part, chondroitin sulfate 180-230 part, calcium carbonate 140-170 part, bone collagen 50-80 part, dolomol 3-8 part.
The preparation method of the described ammonia sugar health products that can increase skeleton nutrition and raising bone density, its step is by weight:
(1), got the bone collagen 50-80 part after 80 mesh sieves, joined in the calcium carbonate 140-170 part after 80 mesh sieves, then both are put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture A;
(2) chondroitin sulfate 180-230 part and the D-Glucosamine sulfate potassium chloride 220-280 part after pulverizing and mistake 80 mesh sieves added 80 mesh sieves in the mixture A, preparing in step (1) after, then three is put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture B;
(3) the dolomol 3-8 part of, getting after 80 mesh sieves joins in multidirectional three-dimensional motion mixer, again the mixture B of preparation in step (2) is joined in multidirectional three-dimensional motion mixer and mixed with dolomol with incremental method, mixture B increases progressively with 3 times of amounts, in multidirectional three-dimensional motion mixer, mix 5min at every turn, increase progressively after 3 times, the 4th joins remaining mixture B in the mixture after increasing progressively, in multidirectional three-dimensional motion mixer, always mix, always doing time is 30 minutes, obtains always mixing thing C;
(4), the total mixed thing C of step (3) preparation is respectively charged in capsule shells, make to contain in every capsules total mixed thing C0.67 ± 0.05 gram;
(5), capsule that step (4) is prepared puts into capsule polisher hopper and carries out capsule polishing, choose polished capsule and be and prepare ammonia sugar health products.
Described preparation method, whole preparation process completes in cleanliness factor is 300,000 grades of environment.
In use, the amount of putting into of mixed material is no more than 2/3rds of this machine total capacity to described multidirectional three-dimensional motion mixer, and described capsule shells is No. 00 capsule shells.
The ammonia sugar health products that the present invention relates to will be filled in lighttight capsule damp and hot unsettled supplementary material, can prevent airborne oxygen, the impact of light on content, improve stability; And capsule outward appearance is bright and clean, attractive in appearance, can cover the uncomfortable taste of medicine; The synergy that these ammonia sugar health products make full use of each component is theoretical, improves product nutrition balance, and these ammonia sugar health products can promote new bone to form and union, and enough nutrition is provided, and promote regenerating bone or cartilage.The factors such as it is Powdered that the preparation method of this ammonia sugar health products considers that raw material is, and particle size differences is little, pulverize indivedual raw materials, then by raw material sieve, mix, the step such as filling, polishing makes finished capsule product.In this preparation method, do not adopt and have granulating process wet, hot factor, to avoid as far as possible causing the unsettled technical process of product.Scientific formulation, the reliable effect of this ammonia sugar health products, human body is had no side effect, preparation method is mature and stable, can industrial-scale production.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, invention is further illustrated.
Fig. 1 is preparation technology's schematic flow sheet that the present invention can increase the ammonia sugar health products of skeleton nutrition and raising bone density;
The specific embodiment
In conjunction with the accompanying drawings, the present invention is further detailed explanation.The schematic diagram of accompanying drawing for simplifying, basic structure of the present invention is only described in a schematic way, so it only shows the formation relevant with the present invention.
Embodiment mono-: can increase the ammonia sugar health products of skeleton nutrition and raising bone density, its component is by weight: 220 parts of D-Glucosamine sulfate potassium chlorides, 180 parts of chondroitin sulfates, 140 parts, calcium carbonate, 50 parts of bone collagens, 3 parts of dolomols.
The preparation method of the described ammonia sugar health products that can increase skeleton nutrition and raising bone density, its step is by weight:
(1), got 50 parts of bone collagens after 80 mesh sieves, joined in 140 parts, calcium carbonate after 80 mesh sieves, then both are put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture A;
(2) add 80 mesh sieves in the mixture A, preparing in step (1) after, 180 parts of chondroitin sulfates and the D-Glucosamine sulfate potassium chloride after pulverizing and mistake 80 mesh sieves were 220 parts, then three is put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture B590 part;
(3), getting 3 parts of dolomols after 80 mesh sieves joins in multidirectional three-dimensional motion mixer, again the mixture B of preparation in step (2) is joined in multidirectional three-dimensional motion mixer and mixed with dolomol with incremental method, mixture B increases progressively with 3 times of amounts: in 3 parts of dolomols, add 10 parts of mixture B for the first time, in multidirectional three-dimensional motion mixer, mix after 5min, increase progressively for the first time and add 30 parts of mixture B, again start multidirectional three-dimensional motion mixer, mix after 5min, increase progressively for the second time and add 90 parts of mixture B, start for the third time multidirectional three-dimensional motion mixer, mix after 5min, increase progressively for the third time and add 270 parts of mixture B, start multidirectional three-dimensional motion mixer the 4th time, mix after 5min, remaining mixture B190 part is joined in multidirectional three-dimensional motion mixer, in multidirectional three-dimensional motion mixer, always mix, always do time is 30 minutes, obtain always mixing thing C,
(4), the total mixed thing C of step (3) preparation is respectively charged in capsule shells, make to contain in every capsules total mixed thing C0.67 ± 0.05 gram;
(5), capsule that step (4) is prepared puts into capsule polisher hopper and carries out capsule polishing, choose polished capsule and be and prepare ammonia sugar health products.
Described preparation method, whole preparation process completes in cleanliness factor is 300,000 grades of environment.
In use, the amount of putting into of mixed material is no more than 2/3rds of this machine total capacity to described multidirectional three-dimensional motion mixer, and described capsule shells is No. 00 capsule shells.
Embodiment bis-: can increase the ammonia sugar health products of skeleton nutrition and raising bone density, its component is by weight: 245 parts of D-Glucosamine sulfate potassium chlorides, 220 parts of chondroitin sulfates, 160 parts, calcium carbonate, 70 parts of bone collagens, 6 parts of dolomols.
The preparation method of the described ammonia sugar health products that can increase skeleton nutrition and raising bone density, its step is by weight:
(1), got 70 parts of bone collagens after 80 mesh sieves, joined in 160 parts, calcium carbonate after 80 mesh sieves, then both are put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture A;
(2) add 80 mesh sieves in the mixture A, preparing in step (1) after, 220 parts of chondroitin sulfates and the D-Glucosamine sulfate potassium chloride after pulverizing and mistake 80 mesh sieves were 245 parts, then three is put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture B;
(3), getting 6 parts of dolomols after 80 mesh sieves joins in multidirectional three-dimensional motion mixer, again the mixture B of preparation in step (2) is joined in multidirectional three-dimensional motion mixer and mixed with dolomol with incremental method, mixture B increases progressively with 3 times of amounts, in multidirectional three-dimensional motion mixer, mix 5min at every turn, increase progressively after 3 times, the 4th joins remaining mixture B in the mixture after increasing progressively, in multidirectional three-dimensional motion mixer, always mix, always doing time is 30 minutes, obtains always mixing thing C;
(4), the total mixed thing C of step (3) preparation is respectively charged in capsule shells, make to contain in every capsules total mixed thing C0.67 ± 0.05 gram;
(5), capsule that step (4) is prepared puts into capsule polisher hopper and carries out capsule polishing, choose polished capsule and be and prepare ammonia sugar health products.
Described preparation method, whole preparation process completes in cleanliness factor is 300,000 grades of environment.
In use, the amount of putting into of mixed material is no more than 2/3rds of this machine total capacity to described multidirectional three-dimensional motion mixer, and described capsule shells is No. 00 capsule shells.
Embodiment tri-: can increase the ammonia sugar health products of skeleton nutrition and raising bone density, its component is by weight: 280 parts of D-Glucosamine sulfate potassium chlorides, 230 parts of chondroitin sulfates, 170 parts, calcium carbonate, 80 parts of bone collagens, 8 parts of dolomols.
The preparation method of the described ammonia sugar health products that can increase skeleton nutrition and raising bone density, its step is by weight:
(1), got 80 parts of bone collagens after 80 mesh sieves, joined in 170 parts, calcium carbonate after 80 mesh sieves, then both are put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture A;
(2) add 80 mesh sieves in the mixture A, preparing in step (1) after, 230 parts of chondroitin sulfates and the D-Glucosamine sulfate potassium chloride after pulverizing and mistake 80 mesh sieves were 280 parts, then three is put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture B;
(3), getting 8 parts of dolomols after 80 mesh sieves joins in multidirectional three-dimensional motion mixer, again the mixture B of preparation in step (2) is joined in multidirectional three-dimensional motion mixer and mixed with dolomol with incremental method, mixture B increases progressively with 3 times of amounts, in multidirectional three-dimensional motion mixer, mix 5min at every turn, increase progressively after 3 times, the 4th joins remaining mixture B in the mixture after increasing progressively, in multidirectional three-dimensional motion mixer, always mix, always doing time is 30 minutes, obtains always mixing thing C;
(4), the total mixed thing C of step (3) preparation is respectively charged in capsule shells, make to contain in every capsules total mixed thing C0.67 ± 0.05 gram;
(5), capsule that step (4) is prepared puts into capsule polisher hopper and carries out capsule polishing, choose polished capsule and be and prepare ammonia sugar health products.
Described preparation method, whole preparation process completes in cleanliness factor is 300,000 grades of environment.
In use, the amount of putting into of mixed material is no more than 2/3rds of this machine total capacity to described multidirectional three-dimensional motion mixer, and described capsule shells is No. 00 capsule shells.
A kind of ammonia sugar health products that can increase skeleton nutrition and raising bone density that the present invention relates to are the health foods made from D-Glucosamine sulfate potassium chloride, chondroitin sulfate, calcium carbonate, bone collagen primary raw material, have the health care that increases bone density.The ammonia sugar health products that the present invention relates to will be filled in lighttight capsule damp and hot unsettled supplementary material, can prevent airborne oxygen, the impact of light on content, improve stability; And capsule outward appearance is bright and clean, attractive in appearance, can cover the uncomfortable taste of medicine; The synergy that these ammonia sugar health products make full use of each component is theoretical, improves product nutrition balance, and these ammonia sugar health products can promote new bone to form and union, and enough nutrition is provided, and promote regenerating bone or cartilage.The factors such as it is Powdered that the preparation method of this ammonia sugar health products considers that raw material is, and particle size differences is little, pulverize indivedual raw materials, then by raw material sieve, mix, the step such as filling, polishing makes finished capsule product.In this preparation method, do not adopt and have granulating process wet, hot factor, to avoid as far as possible causing the unsettled technical process of product.Scientific formulation, the reliable effect of this ammonia sugar health products, human body is had no side effect, preparation method is mature and stable, can industrial-scale production.
Claims (5)
1. can increase the ammonia sugar health products of skeleton nutrition and raising bone density, it is characterized in that its component is by weight: D-Glucosamine sulfate potassium chloride 220-280 part, chondroitin sulfate 180-230 part, calcium carbonate 140-170 part, bone collagen 50-80 part, dolomol 3-8 part.
2. the preparation method that can increase skeleton nutrition and improve the ammonia sugar health products of bone density according to claim 1, is characterized in that its step is by weight:
(1), got the bone collagen 50-80 part after 80 mesh sieves, joined in the calcium carbonate 140-170 part after 80 mesh sieves, then both are put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture A;
(2) chondroitin sulfate 180-230 part and the D-Glucosamine sulfate potassium chloride 220-280 part after pulverizing and mistake 80 mesh sieves added 80 mesh sieves in the mixture A, preparing in step (1) after, then three is put into multidirectional three-dimensional motion mixer and mix 15 minutes, obtain mixture B;
(3) the dolomol 3-8 part of, getting after 80 mesh sieves joins in multidirectional three-dimensional motion mixer, again the mixture B of preparation in step (2) is joined in multidirectional three-dimensional motion mixer and mixed with dolomol with incremental method, mixture B increases progressively with 3 times of amounts, in multidirectional three-dimensional motion mixer, mix 5min at every turn, increase progressively after 3 times, the 4th joins remaining mixture B in the mixture after increasing progressively, in multidirectional three-dimensional motion mixer, always mix, always doing time is 30 minutes, obtains always mixing thing C;
(4), the total mixed thing C of step (3) preparation is respectively charged in capsule shells, make to contain in every capsules total mixed thing C0.67 ± 0.05 gram;
(5), capsule that step (4) is prepared puts into capsule polisher hopper and carries out capsule polishing, choose polished capsule and be and prepare ammonia sugar health products.
3. preparation method according to claim 2, is characterized in that: whole preparation process completes in cleanliness factor is 300,000 grades of environment.
4. preparation method according to claim 2, is characterized in that: in use, the amount of putting into of mixed material is no more than 2/3rds of this machine total capacity to described multidirectional three-dimensional motion mixer.
5. preparation method according to claim 2, is characterized in that: described capsule shells is No. 00 capsule shells.
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CN105363023A (en) * | 2015-11-11 | 2016-03-02 | 深圳太太药业有限公司 | Composition with effects of protecting joints and increasing bone mineral density and preparation method of composition |
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叶礼红等: "氨糖软骨素片增加骨密度动物实验研究", 《现代预防医学》 * |
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边玲等: "硫酸软骨素用于治疗骨关节炎的制剂", 《食品与药品》 * |
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CN105363023A (en) * | 2015-11-11 | 2016-03-02 | 深圳太太药业有限公司 | Composition with effects of protecting joints and increasing bone mineral density and preparation method of composition |
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