CN105707569A - Chewing tablet capable of enhancing bone mineral density and supplementing vitamin D as well as production method thereof - Google Patents
Chewing tablet capable of enhancing bone mineral density and supplementing vitamin D as well as production method thereof Download PDFInfo
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- CN105707569A CN105707569A CN201410705384.7A CN201410705384A CN105707569A CN 105707569 A CN105707569 A CN 105707569A CN 201410705384 A CN201410705384 A CN 201410705384A CN 105707569 A CN105707569 A CN 105707569A
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Abstract
The invention discloses a chewing tablet capable of enhancing bone mineral density and supplementing vitamin D as well as a production method thereof. The chewing tablet capable of enhancing bone mineral density and supplementing vitamin D is prepared by raw materials of calcium carbonate, vitamin D, powdered sugar, dextrin, carboxymethylcellulose sodium, and magnesium stearate; and the production method comprises the following steps: crushing, mixing, granulating, drying, tabletting, dressing, and packaging. The chewing tablet has obvious effect for supplementing the vitamin D, is capable of enhancing calcium absorption by human body, has effective health care effect for human body, and enhancing immunity of human body.
Description
Technical field:
The present invention relates to health product technology field, be specifically related to a kind of chewable tablet strengthening bone density and vitamin D and production method thereof.
Background technology
Calcium carbonate is supplement the main source of calcium in body as food enrichment.Calcium accounts for 1.5% in human body, and wherein 99% exists in skeleton and tooth, mainly comprises composition for skeleton and tooth, and calcium also has restraining cardiac muscle flexible, helps blood clotting, regulates the balance of other mineral, and make the performances such as enzyme activation.From the human body degree of absorption for calcium, though the absorbance of organic calcium is high, but expensive, and the big calcium content of molecular weight is few, absorbs same amount of calcium consumption big.Therefore in food, precipitated calcium carbonate ratio is adopted conveniently.
Vitamin D is a kind of fatsoluble vitamin, is also regarded as a kind of hormone precursor acting on Ca,P metabolism, and it and sunlight have substantial connection, so being again " sunlight vitamin ".Vitamin D is that family's A, B, C, D ring structure is identical, but the general name of the class complex that side chain is different, the architectural source of A, B, C, D ring is in the ring penta hydrogen alkene phenanthrene ring structure of steroid, the vitamin D being currently known has at least 10 kinds, but the most important thing is vitamin D2 (vitamin D2) and vitamin D3 (cholecalciferol).Vitamin D3 has following physiological function: 1, improves the human body absorption to calcium, phosphorus, makes the level of plasma calcium and blood plasma phosphorus reach capacity degree.2, promote growth and skeleton calcification, promote that tooth perfects；3, increased the absorption of phosphorus by intestinal wall, and increased the re-absorption of phosphorus by renal tubules；4, the normal level of citrate in blood is maintained；5, prevent aminoacid from being lost by kidney.For rickets, osteomalacia and infantile tetany, rickets has dental caries person concurrently and also can prevent and treat with these product.Heavy dose is also used for tuberculosis of skin, skin and the various lupus erythematosus of mucosa etc..
In the market to vitamin D with to strengthen the medicine of bone density, health product kind more, but most product compositions are complicated, side effect is big, Some Drugs even can destroy the inner equilibrium of human body, health is constituted a threat to, and teabag drink kind of being correlated with is a lot, but adjuvant treatment effect and health-care effect are general, the market demand can not be met, thus market lacks one very much and has no side effect, have and human body should be had additional nutrients, be beneficial to the enhancing bone density of health and the chewable tablet of vitamin D and production method thereof.
Summary of the invention:
It is an object of the invention to provide a kind of chewable tablet strengthening bone density and vitamin D of a kind of effect having and strengthening bone density and vitamin D and production method.
The object of the present invention is achieved like this.A kind of chewable tablet strengthening bone density and vitamin D, it is characterised in that: it is made up of the raw material of following weight percentage ratio, calcium carbonate 70-80%, vitamin D3 100,000 IU/g；Icing Sugar 15-20%, dextrin 3-8%, sodium carboxymethyl cellulose 1-3%, magnesium stearate 1-3%.
Wherein the percentage by weight of various raw materials is, calcium carbonate 75%, vitamin D3 100,000 IU/g；Icing Sugar 18%, dextrin 5%, sodium carboxymethyl cellulose 2%, magnesium stearate 2%.
Technical process is: pulverizing, mixing, granulation, dry, tabletting, coating, packaging, and concrete operation method follows these steps to successively:
1. pulverize: calcium carbonate, white sugar, dextrin, dimension element D3, carmethose, magnesium stearate in described raw material are crossed respectively 80 mesh sieves, prepare each raw material powder respectively, standby；
2. mixing: the calcium carbonate after pulverizing, white sugar, dextrin being put into and fill mixing 20 minutes in trough type mixing machine, soft material made by the mixed liquor adding dimension element D and carmethose；
3. granulate: the above-mentioned soft material oscillating granulator made is crossed 16 mesh sieves, makes wet granular；
4. dry: the above-mentioned granule made uniformly loosely to be layered in baking material dish, thickness: 0.5-1.5cm, it is placed in heated-air circulation oven dry；Temperature is set to 60-70 DEG C；1-3 hour drying time, dry run turns at any time, it is prevented that granule bonds；
5. tabletting: the granule that will make, carries out tabletting with ZP35B rotary tablet machine, and wherein every tablet weighs 2 grams/piece；
6. coating: the tablet made is carried out film coating；
7. packaging: after degerming for the tablet after film coating, pack.
In this product, vitamin D effect is obvious, strengthens human calcium and absorbs, human body effectively plays health-care effect, strengthens resistance of human body and immunity.
The technological advantage of the present invention is in that: 1, selecting raw material, scientific formulation, production technology is advanced, and its product produces the human body that not only keeps healthy, and conveniently deposits；2, without preservative in product, keep the pharmaceutical compositions of raw material itself, be easily absorbed by the body；3 raw material sources are extensive, add process line short, the easy processing and manufacturing of product.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further illustrated
Embodiment 1:
A kind of chewable tablet strengthening bone density and vitamin D, it is characterised in that: it is made up of the raw material of following weight percentage ratio, calcium carbonate 70-80%, vitamin D3 100,000 IU/g；Icing Sugar 15-20%, dextrin 3-8%, sodium carboxymethyl cellulose 1-3%, magnesium stearate 1-3%.
Wherein the percentage by weight of various raw materials is, calcium carbonate 75%, vitamin D3 100,000 IU/g；Icing Sugar 18%, dextrin 5%, sodium carboxymethyl cellulose 2%, magnesium stearate 2%.
Technical process is: pulverizing, mixing, granulation, dry, tabletting, coating, packaging, and concrete operation method follows these steps to successively:
1. pulverize: calcium carbonate, white sugar, dextrin, dimension element D3, carmethose, magnesium stearate in described raw material are crossed respectively 80 mesh sieves, prepare each raw material powder respectively, standby；
2. mixing: the calcium carbonate after pulverizing, white sugar, dextrin being put into and fill mixing 20 minutes in trough type mixing machine, soft material made by the mixed liquor adding dimension element D and carmethose；
3. granulate: the above-mentioned soft material oscillating granulator made is crossed 16 mesh sieves, makes wet granular；
4. dry: the above-mentioned granule made uniformly loosely to be layered in baking material dish, thickness: 0.5-1.5cm, it is placed in heated-air circulation oven dry；Temperature is set to 60-70 DEG C；1-3 hour drying time, dry run turns at any time, it is prevented that granule bonds；
5. tabletting: the granule that will make, carries out tabletting with ZP35B rotary tablet machine, and wherein every tablet weighs 2 grams/piece；
6. coating: the tablet made is carried out film coating；
7. packaging: after degerming for the tablet after film coating, pack.
Claims (3)
1. the chewable tablet strengthening bone density and vitamin D, it is characterised in that: it is made up of the raw material of following weight percentage ratio, calcium carbonate 70-80%, vitamin D3 100,000 IU/g；Icing Sugar 15-20%, dextrin 3-8%, sodium carboxymethyl cellulose 1-3%, magnesium stearate 1-3%.
2. a kind of chewable tablet strengthening bone density and vitamin D according to claim 1, it is characterised in that: wherein the percentage by weight of various raw materials is, calcium carbonate 75%, vitamin D3 100,000 IU/g；Icing Sugar 18%, dextrin 5%, sodium carboxymethyl cellulose 2%, magnesium stearate 2%.
3. the production method of a kind of chewable tablet strengthening bone density and vitamin D according to claim 1-2, it is characterized in that: technical process is: pulverizing, mixing, granulation, dry, tabletting, coating, packaging, concrete operation method follows these steps to successively:
Pulverize: calcium carbonate, white sugar, dextrin, dimension element D3, carmethose, magnesium stearate in described raw material are crossed respectively 80 mesh sieves, prepare each raw material powder respectively, standby；
Mixing: the calcium carbonate after pulverizing, white sugar, dextrin being put into and fill mixing 20 minutes in trough type mixing machine, soft material made by the mixed liquor adding dimension element D and carmethose；
Granulate: the above-mentioned soft material oscillating granulator made is crossed 16 mesh sieves, makes wet granular；
Dry: the above-mentioned granule made uniformly loosely to be layered in baking material dish, thickness: 0.5-1.5cm, it is placed in heated-air circulation oven dry；Temperature is set to 60-70 DEG C；1-3 hour drying time, dry run turns at any time, it is prevented that granule bonds；
Tabletting: the granule that will make, carries out tabletting with ZP35B rotary tablet machine, and wherein every tablet weighs 2 grams/piece；
Coating: the tablet made is carried out film coating；
Packaging: after degerming for the tablet after film coating, pack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410705384.7A CN105707569A (en) | 2014-12-01 | 2014-12-01 | Chewing tablet capable of enhancing bone mineral density and supplementing vitamin D as well as production method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410705384.7A CN105707569A (en) | 2014-12-01 | 2014-12-01 | Chewing tablet capable of enhancing bone mineral density and supplementing vitamin D as well as production method thereof |
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| Publication Number | Publication Date |
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| CN105707569A true CN105707569A (en) | 2016-06-29 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410705384.7A Pending CN105707569A (en) | 2014-12-01 | 2014-12-01 | Chewing tablet capable of enhancing bone mineral density and supplementing vitamin D as well as production method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106954778A (en) * | 2017-03-31 | 2017-07-18 | 广州市健鸣春生物科技有限公司 | A kind of suitable pregnancy period supplement Sugarless type Biocal and preparation method thereof |
| CN107166876A (en) * | 2017-05-13 | 2017-09-15 | 上药东英（江苏）药业有限公司 | A kind of energy-efficient perindopril tert-butylamine piece particle drying technique |
| CN113975240A (en) * | 2021-11-22 | 2022-01-28 | 国圣制药(上海)有限公司 | Production method of calcium vitamin D tablets |
-
2014
- 2014-12-01 CN CN201410705384.7A patent/CN105707569A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106954778A (en) * | 2017-03-31 | 2017-07-18 | 广州市健鸣春生物科技有限公司 | A kind of suitable pregnancy period supplement Sugarless type Biocal and preparation method thereof |
| CN107166876A (en) * | 2017-05-13 | 2017-09-15 | 上药东英（江苏）药业有限公司 | A kind of energy-efficient perindopril tert-butylamine piece particle drying technique |
| CN113975240A (en) * | 2021-11-22 | 2022-01-28 | 国圣制药(上海)有限公司 | Production method of calcium vitamin D tablets |
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Application publication date: 20160629 |