CN103948885A - Traditional Chinese medicine for treating gastric cancer, and preparation method thereof - Google Patents
Traditional Chinese medicine for treating gastric cancer, and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating gastric cancer. The traditional Chinese medicine is prepared by using the following raw medicines, by weight, 12-30 parts of Radix Curcumae Aromaticae, 15-40 parts of Pinellia Tuber, 5-20 parts of Artemisia capillaries, 2-10 parts of sliced ginger, 3-15 parts of rhizoma gastrodiae, 5-20 parts of unprepared Atractylis lancea, 10-20 parts of Cordyceps sinensis, 3-15 parts of Lithospermum erythrorhizon, 4-10 parts of Isatis Root, 5-20 parts of radix bupleuri, 11-25 parts of Camomile, 12-25 parts of honeysuckle flower, 13-27 parts of Trichosanthis Radix, 1-3 parts of Lophatherum gracile, 2-6 parts of Wrinkled Gianthyssop, 2-10 parts of Radix Puerariae, 2-10 parts of hawthorn fruit, 2-10 parts of periostracum cicadae, 6-8 parts of Akebia Stem, 3-7 parts of soybean, 8-10 parts of betel nut, 4-6 parts of Phytolacca acinosa Roxb, 4-8 parts of Gentiana macrophylla, 3-6 parts of Chinese prickly ash, 6-12 parts of Musa sapientum L., 3-8 parts of Sophora flavescens and 5-20 parts of millet sprout.
Description
Technical field
The invention belongs to technical field of Chinese medicines, specifically a kind of Chinese medicine for the treatment of gastric cancer and preparation method thereof.
Background technology
Tumor be body under various carcinogenic factor effects, some cells of local organization lose the normal regulation to its growth on gene level, cause its clonal abnormality hypertrophy and the abnormality that forms; Gastric cancer is one of common malignant tumor of China, and incidence gastric cancer has obvious region difference, in northwest and the coastal region in east China incidence gastric cancer rate of China, than southern area, is evident as height.
In the long-term edible crowd who smokes roasting, salted food, gastric distal end carcinoma sickness rate is high, relevant with the carcinogen such as nitrite in food, mycotoxin, polycyclic aromatic hydrocarbon compounds or procarcinogen content height; Smoker's incidence gastric cancer danger is high by 50% compared with non-smoker; Gastric cancer is divided into early gastric cancer and advanced gastric carcinoma, no matter early gastric cancer range size, early lesion only limits to mucosa and tela submucosa, and general asymptomatic or only have light symptoms, when gastric cancer enters after middle and advanced stage, the cancerous lesion of stomach diffuses to whole stomach,
The treatment of gastric cancer mainly contains four kinds of operative treatment, radiotherapy, chemotherapy and treatments by Chinese herbs, and operative treatment survival probability is larger; The 2nd, radiotherapy.Radiation complication is more, even causes partial loss of function; For late tumor patient, the effect of radiation therapy is not intact, poor, the older patient of while body constitution, and it is more critically ill that continuation radiotherapy can only be led debilitant life, accelerated death; The 3rd, chemotherapy.Chemotherapy is the fastest Therapeutic Method that improves in oncotherapy in recent years.But chemotherapeutics normal " right and wrong are unclear ", " failing to differentiate between the enemy and ourselves ", in killing tumor cell, also killed and wounded human normal cell; The 4th, treatment by Chinese herbs, the side effect for the treatment of by Chinese herbs is little, and the side effect bringing to human body is little.
Summary of the invention
The problem to be solved in the present invention is for above problem, provides side effect little, a kind of Chinese medicine for the treatment of gastric cancer that therapeutic effect is good and preparation method thereof.
For addressing the above problem, the technical solution adopted in the present invention is:
Treat a Chinese medicine for gastric cancer, by the crude drug of following weight portion, made: Radix Curcumae 12-30 part, Rhizoma Pinelliae 15-40 part, Herba Artemisiae Scopariae 5-20 part, ginger slice 2-10 part, RHIZONA GASTRODIAE 3-15 part, raw thatch art 5-20 part, Cordyceps 10-20 part, Radix Arnebiae (Radix Lithospermi) 3-15 part, Radix Isatidis 4-10 part, Radix Bupleuri 5-20 part; Flos Chrysanthemi 11-25 part, Flos Lonicerae 12-25 part, Radix Trichosanthis 13-27 part, Herba Lophatheri 1-3 part, Herba Pogostemonis 2-6 part, Pachyrhizua angulatus 2-10 part, Fructus Crataegi 2-10 part, Periostracum Cicadae 2-10 part; Caulis Akebiae 6-8 part, Semen Glycines 3-7 part, Semen Arecae 8-10 part, trade route 4-6 part, Radix Gentianae Macrophyllae 4-8 part, Pericarpium Zanthoxyli 3-6 part, Banana Root 6-12 part, Chinese scholartree 3-8 part, Fructus Setariae Germinatus 5-20 part.
Below the further improvement to technique scheme:
Treat a Chinese medicine for gastric cancer, by the crude drug of following weight portion, made: 24 parts of Radix Curcumaes, 28 parts of the Rhizoma Pinelliaes, 16 parts of Herba Artemisiae Scopariae, 7 parts of ginger slices, 9 parts, Rhizoma Gastrodiae, 12 parts of raw thatch arts, 15 parts of Cordyceps, 8 parts of Radix Arnebiae (Radix Lithospermi)s, 7 parts of Radix Isatidis, 12 parts of Radix Bupleuri; 18 parts of Flos Chrysanthemis, 20 parts of Flos Loniceraes, 20 parts of Radix Trichosanthis, 2 parts of Herba Lophatheris, 4 parts of Herba Pogostemoniss, 7 parts of Pachyrhizua angulatus, 6 parts of Fructus Crataegis, 6 parts of Periostracum Cicadaes; 7 parts of Caulis Akebiaes, 5 parts of Semen Glyciness, 9 parts of Semen Arecaes, 5 parts, trade route, 6 parts of Radix Gentianae Macrophyllae, 4 parts, Pericarpium Zanthoxyli, 8 parts of Banana Roots, 5 parts of Chinese scholartrees, 12 parts of Fructus Setariae Germinatuss.
As further improvement:
A preparation method for the treatment of the Chinese medicine of gastric cancer, comprises the following steps:
1), get the crude drug of above-mentioned weight standby;
2), get Banana Root and soak 1-2 hour with vinegar, then drop goes out Banana Root, puts into medicated beer and soaks 1-2 hour, drains standbyly, obtains Banana Root processed;
3), the Semen Arecae of above-mentioned weight is soaked with light salt brine, drain;
4), yellow wine for Periostracum Cicadae is soaked to 1-2 hour, be dipped to softness;
5), by the Radix Curcumae of above-mentioned weight, the Rhizoma Pinelliae, Herba Artemisiae Scopariae, ginger slice, Rhizoma Gastrodiae, raw thatch art, Radix Arnebiae (Radix Lithospermi), Radix Isatidis, Radix Bupleuri; Flos Chrysanthemi, Flos Lonicerae, Radix Trichosanthis, Herba Lophatheri, Herba Pogostemonis, Pachyrhizua angulatus, Fructus Crataegi, Caulis Akebiae, Semen Glycines, Semen Arecae, trade route, Radix Gentianae Macrophyllae, Pericarpium Zanthoxyli, Fructus Setariae Germinatus add the decocting of 10 times of crude drug gross weights to boil, be heated to boiling, boiling 20-40 minute, then add the Bin youth who makes in step 3), maintain the temperature at 80-90 degree and decoct 10-20 minute, add step 2) in the Banana Root processed that makes; Maintain the temperature at 80-90 degree and decoct 10-20 minute, the Periostracum Cicadae that simultaneously adds Cordyceps and step 4) to make, is warming up to 100 degree and decocts 2-8 minute, and drop goes out medicinal liquid.
As further improvement:
Described Banana Root is the delicate radical bud of banana plant.
The concentration of the light salt brine in step 3 is 1%.
While taking, medicinal liquid being divided into two parts, is that 50-60 takes while spending at medicinal liquid, and minute sooner or later twice one after each meal, 2 weeks is a course for the treatment of.
Through clinical trial, the present invention has good curative effect to treatment gastric cancer, generation and diffusion that can anticancer, safety, has no side effect, treatment cost is low, be two weeks per course for the treatment of, takes and both can take effect a course for the treatment of, take 2 to 3 courses for the treatment of after symptom greatly alleviate, particularly remarkable in the commitment effect of gastric cancer, gastric cancer middle and advanced stage is also had to good retarding action.
The specific embodiment
Embodiment 1, and a kind of Chinese medicine for the treatment of gastric cancer is made by the crude drug of following weight: 24 grams of Radix Curcumaes, 28 grams of the Rhizoma Pinelliaes, 16 grams of Herba Artemisiae Scopariae, 7 grams of ginger slices, 9 grams, Rhizoma Gastrodiae, 12 grams of raw thatch arts, 15 grams of Cordyceps, 8 grams of Radix Arnebiae (Radix Lithospermi)s, 7 grams of Radix Isatidis, 12 grams of Radix Bupleuri; 18 grams of Flos Chrysanthemis, 20 grams of Flos Loniceraes, 20 grams of Radix Trichosanthis, 2 grams of Herba Lophatheris, 4 grams of Herba Pogostemoniss, 7 grams of Pachyrhizua angulatus, 6 grams of Fructus Crataegis, 6 grams of Periostracum Cicadaes; 7 grams of Caulis Akebiaes, 5 grams of Semen Glyciness, 9 grams of Semen Arecaes, 5 grams, trade route, 6 grams of Radix Gentianae Macrophyllae, 4 grams, Pericarpium Zanthoxyli, 8 grams of Banana Roots, 5 grams of Chinese scholartrees, 12 grams of Fructus Setariae Germinatuss.
Embodiment 2, and a kind of Chinese medicine for the treatment of gastric cancer is made by the crude drug of following weight: 12 grams of Radix Curcumaes, 15 grams of the Rhizoma Pinelliaes, 5 grams of Herba Artemisiae Scopariae, 2 grams of ginger slices, 3 grams of RHIZONA GASTRODIAE, 5 grams of raw thatch arts, 10 grams of Cordyceps, 3 grams of Radix Arnebiae (Radix Lithospermi)s, 4 grams of Radix Isatidis, 5 grams of Radix Bupleuri; 11 grams of Flos Chrysanthemis, 12 grams of Flos Loniceraes, 13 grams of Radix Trichosanthis, 1 gram of Herba Lophatheri, 2 grams of Herba Pogostemoniss, 2 grams of Pachyrhizua angulatus, 2 grams of Fructus Crataegis, 2 grams of Periostracum Cicadaes; 6 grams of Caulis Akebiaes, 3 grams of Semen Glyciness, 8 grams of Semen Arecaes, 4 grams, trade route, 4 grams of Radix Gentianae Macrophyllae, 3 grams, Pericarpium Zanthoxyli, 6 grams of Banana Roots, 3 grams of Chinese scholartrees, 5 grams of Fructus Setariae Germinatuss.
Embodiment 3, treat a Chinese medicine for gastric cancer, by the crude drug of following weight, made: 30 grams of Radix Curcumaes, 40 grams of the Rhizoma Pinelliaes, 20 grams of Herba Artemisiae Scopariae, 10 grams of ginger slices, 15 grams of RHIZONA GASTRODIAE, 20 grams of raw thatch arts, 20 grams of Cordyceps, 15 grams of Radix Arnebiae (Radix Lithospermi)s, 10 grams of Radix Isatidis, 20 grams of Radix Bupleuri; 25 grams of Flos Chrysanthemis, 25 grams of Flos Loniceraes, 27 grams of Radix Trichosanthis, 3 grams of Herba Lophatheris, 6 grams of Herba Pogostemoniss, 10 grams of Pachyrhizua angulatus, 10 grams of Fructus Crataegis, 10 grams of Periostracum Cicadaes; 8 grams of Caulis Akebiaes, 7 grams of Semen Glyciness, 10 grams of Semen Arecaes, 6 grams, trade route, 8 grams of Radix Gentianae Macrophyllae, 6 grams, Pericarpium Zanthoxyli, 12 grams of Banana Roots, 8 grams of Chinese scholartrees, 20 grams of Fructus Setariae Germinatuss.
1), the crude drug of getting above-mentioned weight is standby the preparation method of Chinese medicine of the present invention comprises following processing step:; 2), get Banana Root and soak 1-2 hour with vinegar, then drop goes out Banana Root, puts into medicated beer and soaks 1-2 hour, drains standbyly, obtains Banana Root processed; 3), the Semen Arecae of above-mentioned weight is soaked with light salt brine, drain; 4), yellow wine for Periostracum Cicadae is soaked to 1-2 hour, be dipped to softness; 5), by the Radix Curcumae of above-mentioned weight, the Rhizoma Pinelliae, Herba Artemisiae Scopariae, ginger slice, Rhizoma Gastrodiae, raw thatch art, Radix Arnebiae (Radix Lithospermi), Radix Isatidis, Radix Bupleuri; Flos Chrysanthemi, Flos Lonicerae, Radix Trichosanthis, Herba Lophatheri, Herba Pogostemonis, Pachyrhizua angulatus, Fructus Crataegi, Caulis Akebiae, Semen Glycines, Semen Arecae, trade route, Radix Gentianae Macrophyllae, Pericarpium Zanthoxyli, Fructus Setariae Germinatus add the decocting of 10 times of crude drug gross weights to boil, be heated to boiling, boiling 20-40 minute, then add the Bin youth who makes in step 3), maintain the temperature at 80-90 degree and decoct 10-20 minute, add step 2) in the Banana Root processed that makes; Maintain the temperature at 80-90 degree and decoct 10-20 minute, the Periostracum Cicadae that simultaneously adds Cordyceps and step 4) to make, is warming up to 100 degree and decocts 2-8 minute, and drop goes out medicinal liquid.
While taking, medicinal liquid being divided into two parts, is that 50-60 takes while spending at medicinal liquid, and minute sooner or later twice one after each meal, 2 weeks is a course for the treatment of.
500 of-2014 Nian the courts in 2010 suffer from the patient of gastric cancer, have 210 routine patients to take 3 courses for the treatment of of Chinese medicine of the present invention, and 210 examples adopt chemotherapy, radiotherapy and operations, test.
70 examples are taken the Chinese medicine in the embodiment of the present invention 1, as 1 group for the treatment of; 70 examples are taken the Chinese medicine in the embodiment of the present invention 2, as 2 groups of treatments; 70 examples are taken the Chinese medicine in the embodiment of the present invention 3, as 3 groups of treatments; 70 examples adopt 1 group in contrast of operative treatment, and 70 examples adopt 2 groups in contrast of radiotherapy in the treatment, and 70 examples adopt 3 groups in contrast of chemotherapy, and 6 groups of cases have comparability on the clinical age, and experimental result is in Table one.
Through experiment, the proportioning of medicine of the present invention is Radix Curcumae 12-30 part, Rhizoma Pinelliae 15-40 part, Herba Artemisiae Scopariae 5-20 part, ginger slice 2-10 part, RHIZONA GASTRODIAE 3-15 part, raw thatch art 5-20 part, Cordyceps 10-20 part, Radix Arnebiae (Radix Lithospermi) 3-15 part, Radix Isatidis 4-10 part, Radix Bupleuri 5-20 part; Flos Chrysanthemi 11-25 part, Flos Lonicerae 12-25 part, Radix Trichosanthis 13-27 part, Herba Lophatheri 1-3 part, Herba Pogostemonis 2-6 part, Pachyrhizua angulatus 2-10 part, Fructus Crataegi 2-10 part, Periostracum Cicadae 2-10 part; Caulis Akebiae 6-8 part, Semen Glycines 3-7 part, Semen Arecae 8-10 part, trade route 4-6 part, Radix Gentianae Macrophyllae 4-8 part, Pericarpium Zanthoxyli 3-6 part, Banana Root 6-12 part, when Chinese scholartree 3-8 part, Fructus Setariae Germinatus 5-20 part, the curative effect of medicine is far above the curative effect of other weight proportion.
Particularly the proportioning of medicine is at 24 parts of Radix Curcumaes, 28 parts of the Rhizoma Pinelliaes, 16 parts of Herba Artemisiae Scopariae, 7 parts of ginger slices, 9 parts, Rhizoma Gastrodiae, 12 parts of raw thatch arts, 15 parts of Cordyceps, 8 parts of Radix Arnebiae (Radix Lithospermi)s, 7 parts of Radix Isatidis, 12 parts of Radix Bupleuri; 18 parts of Flos Chrysanthemis, 20 parts of Flos Loniceraes, 20 parts of Radix Trichosanthis, 2 parts of Herba Lophatheris, 4 parts of Herba Pogostemoniss, 7 parts of Pachyrhizua angulatus, 6 parts of Fructus Crataegis, 6 parts of Periostracum Cicadaes; 7 parts of Caulis Akebiaes, 5 parts of Semen Glyciness, 9 parts of Semen Arecaes, 5 parts, trade route, 6 parts of Radix Gentianae Macrophyllae, 4 parts, Pericarpium Zanthoxyli, 8 parts of Banana Roots, when 12 parts of 5 parts of Chinese scholartrees, Fructus Setariae Germinatus the curative effect of medicine the most remarkable.
Through experiment, in the embodiment of the present invention, Banana Root is when being the delicate radical bud of banana plant, and the curative effect of medicine is better than old Banana Root from far away; Through experiment, it is concentration while being 1% that Bin youth is better than with direct interpolation Semen Arecae, the particularly light salt brine in step 3 by the drug effect of obtained medicine after saline soak, and the drug effect of obtained medicine is best.
Table one
Through clinical trial, the present invention has good curative effect to treatment gastric cancer, generation and diffusion that can anticancer, safety, have no side effect, be two weeks per course for the treatment of, takes and both can take effect a course for the treatment of, take 2 to 3 courses for the treatment of after symptom greatly alleviate, particularly remarkable in the commitment effect of gastric cancer, gastric cancer middle and advanced stage is also had to good retarding action, and it is better that the present invention takes effect lastingly, can effectively suppress the development of the cancer state of an illness.
After operation, take the embodiment of the present invention 1 Chinese medicine, treat, therapeutic outcome is in Table two.
Table two
From table two, after operation, take the embodiment of the present invention 1 Chinese medicine, to treat, the obvious effective rate for the treatment of improves greatly, and middle and advanced stage patient's the state of an illness is alleviated greatly.
Claims (5)
1. a Chinese medicine for the treatment of gastric cancer, crude drug by following weight portion is made, and it is characterized in that: Radix Curcumae 12-30 part, Rhizoma Pinelliae 15-40 part, Herba Artemisiae Scopariae 5-20 part, ginger slice 2-10 part, RHIZONA GASTRODIAE 3-15 part, raw thatch art 5-20 part, Cordyceps 10-20 part, Radix Arnebiae (Radix Lithospermi) 3-15 part, Radix Isatidis 4-10 part, Radix Bupleuri 5-20 part; Flos Chrysanthemi 11-25 part, Flos Lonicerae 12-25 part, Radix Trichosanthis 13-27 part, Herba Lophatheri 1-3 part, Herba Pogostemonis 2-6 part, Pachyrhizua angulatus 2-10 part, Fructus Crataegi 2-10 part, Periostracum Cicadae 2-10 part; Caulis Akebiae 6-8 part, Semen Glycines 3-7 part, Semen Arecae 8-10 part, trade route 4-6 part, Radix Gentianae Macrophyllae 4-8 part, Pericarpium Zanthoxyli 3-6 part, Banana Root 6-12 part, Chinese scholartree 3-8 part, Fructus Setariae Germinatus 5-20 part.
2. a kind of Chinese medicine for the treatment of gastric cancer as claimed in claim 1, is characterized in that: the crude drug by following weight portion is made: 24 parts of Radix Curcumaes, 28 parts of the Rhizoma Pinelliaes, 16 parts of Herba Artemisiae Scopariae, 7 parts of ginger slices, 9 parts, Rhizoma Gastrodiae, 12 parts of raw thatch arts, 15 parts of Cordyceps, 8 parts of Radix Arnebiae (Radix Lithospermi)s, 7 parts of Radix Isatidis, 12 parts of Radix Bupleuri; 18 parts of Flos Chrysanthemis, 20 parts of Flos Loniceraes, 20 parts of Radix Trichosanthis, 2 parts of Herba Lophatheris, 4 parts of Herba Pogostemoniss, 7 parts of Pachyrhizua angulatus, 6 parts of Fructus Crataegis, 6 parts of Periostracum Cicadaes; 7 parts of Caulis Akebiaes, 5 parts of Semen Glyciness, 9 parts of Semen Arecaes, 5 parts, trade route, 6 parts of Radix Gentianae Macrophyllae, 4 parts, Pericarpium Zanthoxyli, 8 parts of Banana Roots, 5 parts of Chinese scholartrees, 12 parts of Fructus Setariae Germinatuss.
3. a kind of preparation method for the treatment of the Chinese medicine of gastric cancer as claimed in claim 1 or 2, comprises the following steps:
1), get the crude drug of above-mentioned weight standby;
2), get Banana Root and soak 1-2 hour with vinegar, then drop goes out Banana Root, puts into medicated beer and soaks 1-2 hour, drains standbyly, obtains Banana Root processed;
3), the Semen Arecae of above-mentioned weight is soaked with light salt brine, drain;
4), yellow wine for Periostracum Cicadae is soaked to 1-2 hour, be dipped to softness;
5), by the Radix Curcumae of above-mentioned weight, the Rhizoma Pinelliae, Herba Artemisiae Scopariae, ginger slice, Rhizoma Gastrodiae, raw thatch art, Radix Arnebiae (Radix Lithospermi), Radix Isatidis, Radix Bupleuri; Flos Chrysanthemi, Flos Lonicerae, Radix Trichosanthis, Herba Lophatheri, Herba Pogostemonis, Pachyrhizua angulatus, Fructus Crataegi, Caulis Akebiae, Semen Glycines, Semen Arecae, trade route, Radix Gentianae Macrophyllae, Pericarpium Zanthoxyli, Fructus Setariae Germinatus add the decocting of 10 times of crude drug gross weights to boil, be heated to boiling, boiling 20-40 minute, then add the Bin youth who makes in step 3), maintain the temperature at 80-90 degree and decoct 10-20 minute, add step 2) in the Banana Root processed that makes; Maintain the temperature at 80-90 degree and decoct 10-20 minute, the Periostracum Cicadae that simultaneously adds Cordyceps and step 4) to make, is warming up to 100 degree and decocts 2-8 minute, and drop goes out medicinal liquid.
4. a kind of preparation method for the treatment of the Chinese medicine of gastric cancer as claimed in claim 3, is characterized in that: the delicate radical bud that described Banana Root is banana plant.
5. a kind of preparation method for the treatment of the Chinese medicine of gastric cancer as described in claim 3 or 4, is characterized in that: the concentration of the light salt brine in step 3) is 1%.
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| CN1422642A (en) * | 2001-12-04 | 2003-06-11 | 何文法 | Series Chinese medicinal composition for treating tumor |
| CN101683499A (en) * | 2008-09-24 | 2010-03-31 | 王孙勇 | Cancer curing capsule |
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Application publication date: 20140730 |