CN103931954A - Feed additive for regulating and repairing broiler intestines and preparation method of feed additive - Google Patents

Feed additive for regulating and repairing broiler intestines and preparation method of feed additive Download PDF

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Publication number
CN103931954A
CN103931954A CN201410195427.1A CN201410195427A CN103931954A CN 103931954 A CN103931954 A CN 103931954A CN 201410195427 A CN201410195427 A CN 201410195427A CN 103931954 A CN103931954 A CN 103931954A
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broiler
improved
feed additive
regulating
intestines
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CN201410195427.1A
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CN103931954B (en
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甘双友
李玉静
任宏伟
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Hebei Jiaotong Vocational and Technical College
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Hebei Jiaotong Vocational and Technical College
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Abstract

The invention relates to a feed additive for regulating and repairing broiler intestines and a preparation method of the feed additive and belongs to the technical field of poultry feeding. The feed additive comprises components such as sodium butyrate, butyrate and clostridium butyricum, and the broiler intestines can be regulated and repaired, so that the intestinal villus height is improved by about 120 percent, the crypt depth of the broiler intestines is reduced by 50 percent, V/C is improved, the number of harmful bacteria in the broiler intestines is reduced, intestinal development of the broilers is promoted, absorption of nutrient substances is improved, and the immunity of the broilers is improved, so that excessively feeding or ascites syndrome can be solved or improved, the survival rate, feed digestibility and culture benefits of the broilers are improved, and huge economic benefits are brought. Compared with a control group, the feed additive has the advantages that the broiler growth speed is improved by 13 percent, a death elimination rate is reduced by 70 percent, a feed conversion ratio is improved by 4 percent, and the income of a broiler is increased by 0.6yuan after the feed additive is added.

Description

A kind of for regulating and controlling to repair feed addictive of Intestine of Broiler and preparation method thereof
Technical field
The present invention relates to a kind of feed addictive and preparation method thereof, relate in particular to a kind ofly for regulating and controlling to repair feed addictive and preparation method thereof of Intestine of Broiler, belong to bird breeding technology field.
Background technology
Enteron aisle is the digestive organs of poultry maximum, is digestion and the place that absorbs nutrition.Intestinal mucosa layer surface is coated with intestinal villus, and the food entering in enteron aisle resolves into glucose, amino acid, makes after food digestion absorption under the effect of various digestive juices, and residue forms ight soil and is excreted.Once enteron aisle is ill, will causes Disorder of Digestion and A orption, thereby affect the growth of broiler chicken.Research shows, associating or the interaction of different virus, different bacterium and other infectiousness or non-infectious cause of disease, be enough to bring out intestines problem in various degree.Can say that Intestine of Broiler disease is perplexing the development of broiler chicken industry always, at present, aborning, conventionally adopt the method for adding feeding antibiotic to prevent such disease, but antibiotic use has caused problems, as medicament residue, drug resistance, suprainfection and reduction immunity of organisms etc., its application is very limited.
Therefore, need to develop a kind of new technology and regulate and control reparation Intestine of Broiler, stop to use antibiotic, thereby avoid the generation by problems such as the medicament residue, drug resistance, suprainfection and the reduction immunity of organisms that use antibiotic to bring.
Summary of the invention
Technical problem to be solved by this invention is that the defect that overcomes prior art provides a kind of for regulating and controlling to repair the feed addictive of Intestine of Broiler, this additive is under the prerequisite without harm to animal and human body, can repair and to reduce Intestine of Broiler impaired, can replace antibiotics additive completely, and successful.
Technical problem of the present invention is realized by following technical scheme.
For regulating and controlling to repair a feed addictive for Intestine of Broiler, the component that contains following weight portion: sodium butyrate 20~40, methyl butyrate 90~110, clostridium butyricum 90~110, silica 60~80, modified potato starch 70~80.
Preferably, above-mentioned for regulating and controlling to repair the feed addictive of Intestine of Broiler, the component that contains following weight portion: sodium butyrate 30, methyl butyrate 100, clostridium butyricum 100, silica 70, modified potato starch 75.
Sodium butyrate can promote intestinal mucosa to grow, and repairs mucosal epithelium cell, activated lymphocyte; Adjust micro ecology of gastrointestinal tract balance, promote profitable strain propagation; Reduce intestines and stomach pH; Strengthen enteron aisle nospecific immunity, safeguard intestinal health; Have strong synergism with antibiosis, antibacterial growth-promoting effect is obvious.
Clostridium butyricum has four mcroorganism characteristics: the one, promote propagation and the growth of animal intestinal profitable strain, and suppress growth, the breeding of the interior harmful bacteria of enteron aisle and spoilage organisms, correct enteric flora disturbance, reduce the generation of enterotoxin; The 2nd, in animal intestinal, can produce the materials such as B family vitamin, vitamin K, amylase, with health role; The 3rd, the main metabolites butyric acid of clostridium butyricum is the histiocytic regeneration of gut epithelium and repairs Major Nutrient material; The 4th, anaerobism or amphimicrobian bacillus, are not affected by hydrochloric acid in gastric juice, bile acid etc.
Methyl butyrate, sodium butyrate, three compositions of clostridium butyricum are mutually promoted, are superposeed, and are more conducive to decomposite butyric acid, promote growth and the bacterium of enteron aisle to balance each other, and reduce bowel problems and occur, and promote enteron aisle pH value to be controlled at sour environment, ensure intestinal health.
Another object of the present invention is to provide the preparation method of this feed addictive.
The above-mentioned preparation method of feed addictive for regulating and controlling to repair Intestine of Broiler, comprises the following steps:
(1) take methyl butyrate, sodium butyrate and the silica of recipe quantity, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) modified potato starch by step (1) gained mixture and in writing out a prescription is made the fine granularity material of the spray-dried rear formation 0.2~0.5mm of wall material, again fine granularity material is fully mixed with the clostridium butyricum of recipe quantity, obtain of the present invention for regulating and controlling to repair the feed addictive of Intestine of Broiler.
Methyl butyrate can reduce its volatilization after silica supports absorption, sodium butyrate can reduce its stink ability and moisture absorption after the coated processing of silica supports, methyl butyrate, sodium butyrate are through fully mixing with silica, the guarantee that is more conducive to its content with and in the effect performance of enteron aisle, the stability of product be improved significantly, tire more stable.After clostridium butyricum, add is for reducing methyl butyrate and sodium butyrate to bacterium viable count and active impact, being more conducive to it and playing a role at Intestine of Broiler.The stripping of modified potato starch good film-forming property, the transparency high stability and the active ingredient that are conducive to feed addictive.The fine granularity material of 0.2~0.5mm is conducive to the absorption of active ingredient and distribution in vivo, thereby can ensure to play effectiveness.
Of the present invention for regulating and controlling to repair the feed addictive of Intestine of Broiler, the enteron aisle that can realize broiler chicken regulates and repairs, make ileum height of naps improve approximately 120%, reduce the broiler chicken ileum crypts degree of depth approximately 50%, improve V/C, reduce the quantity of Intestine of Broiler harmful bacteria, promote Intestine of Broiler to grow, improve the absorption of nutriment, improve immunity of meat chickens, make " punishment in advance " and ascites symptoms be solved or improve, improve broiler chicken survival rate, feed digestibility and culture benefit, bring huge economic benefit.By with control group comparison, add after this feed addictive and make growth of meat chicken speed improve 13%; Dead mortality declines 70%; Feedstuff-meat ratio improves 4%; A broiler chicken is increased income 0.6 yuan.
Detailed description of the invention
Below by detailed description of the invention, the invention will be further described, but just for helping to understand the present invention, make professional and technical personnel in the field can realize or use the present invention, the present invention do not formed to any restriction.
Embodiment 1 preparation of feed addictive for regulating and controlling to repair Intestine of Broiler of the present invention
Prescription: sodium butyrate 30, butyrate 100, clostridium butyricum 100, silica 70, modified potato starch 75.
Preparation method:
(1) take methyl butyrate, sodium butyrate and the silica of recipe quantity, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) modified potato starch of step (1) gained mixture and recipe quantity is made to the spray-dried rear formation 0.2mm fine granularity material of wall material, again fine granularity material is fully mixed with the clostridium butyricum of recipe quantity, obtain of the present invention for regulating and controlling to repair the feed addictive of Intestine of Broiler.
Embodiment 2 preparation of feed addictive for regulating and controlling to repair Intestine of Broiler of the present invention
Prescription: sodium butyrate 20, butyrate 90, clostridium butyricum 90, silica 60, modified potato starch 70.
Preparation method:
(1) take methyl butyrate, sodium butyrate and the silica of recipe quantity, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) modified potato starch of step (1) gained mixture and recipe quantity is made to the spray-dried rear formation 0.5mm fine granularity material of wall material, again fine granularity material is fully mixed with the clostridium butyricum of recipe quantity, obtain of the present invention for regulating and controlling to repair the feed addictive of Intestine of Broiler.
Embodiment 3 preparation of feed addictive for regulating and controlling to repair Intestine of Broiler of the present invention
Prescription: sodium butyrate 40, butyrate 110, clostridium butyricum 110, silica 80, modified potato starch 80.
Preparation method:
(1) take methyl butyrate, sodium butyrate and the silica of recipe quantity, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) modified potato starch of step (1) gained mixture and recipe quantity is made to the spray-dried rear formation 0.3mm fine granularity material of wall material, again fine granularity material is fully mixed with the clostridium butyricum of recipe quantity, obtain of the present invention for regulating and controlling to repair the feed addictive of Intestine of Broiler.
Embodiment 4 comparative examples
Divide two groups by 180 broiler chicken, first group is test group, test group is used basal feed, second group is control group, 0-7 age in days, 7-14 age in days, 14-28 age in days and 28 ages in days-deliver for sale, in the breeding process of this four-stage, in basal feed, use the embodiment of the present invention 1 prepared for regulating and controlling to repair the feed addictive of Intestine of Broiler, its consumption is to use 300g in basal feed per ton, is also in basal feed per ton, to use sodium butyrate 30g, butyrate 100g, clostridium butyricum 100g, silica 70g, modified potato starch 75g.
Test group and control group, establish 3 repetition groups respectively, 30 broiler chicken of each repetition group, and its object is stability checking, Repeatability checking.
The result of test group and control group contrast (duodenum) when table 1 is delivered for sale
The normal configuration of enteron aisle and function are that nutriment is by fully intestinal villus height, the crypts degree of depth, intestines wall thickness, V/C and the fine hair total surface area of the basic guarantee, particularly enteron aisle of digestion and absorption are to weigh the important indicator of enteron aisle digestion and absorption function.Intestinal villus height and cell quantity are significant correlation, and in finger-like fine hair, the height of fine hair is relevant with its enterocyte quantity.In the time that fine hair is elongated, enterocyte quantity increases; The fine hair in short-term villus cell of maturation reduces, low to the absorbability of nutrient.The crypts degree of depth has reflected cellular survival rate, and cell is the migration from crypts base portion to fine hair end, differentiation constantly, to supplement normally coming off of chorioepithelium.Therefore, crypts can be regarded as the processing factory of fine hair.If this process slows down, the cellular survival rate of base portion reduces, and crypts is shoaled.Crypts shoals and shows that enterocyte maturing rate rises, and absorption function strengthens.Crypts deepens the quickening of explanation tissue metabolism and new organization needs to increase, and means that maintaining desired nutritional increases, and animal production efficiency declines.V/C has reflected the functional status of enteron aisle, and ratio rises, and mucous membrane improves, and digestion and absorption function strengthens, the quickening of growing; Ratio declines, and mucous membrane is impaired, and digestion and absorption function reduces.As shown in Table 1, deliver for sale after 42d compared with control group to broiler chicken, test group can make enteron aisle height of naps bring up to approximately 120%, reduces the Intestine of Broiler crypts degree of depth to approximately 50%, significantly improve V/C, significantly reduce the quantity of Intestine of Broiler harmful bacteria, promote Intestine of Broiler to grow, improve the absorption of nutriment, and significantly reduce the dorking abdominal dropsy of knowing clearly generation, make growth of meat chicken speed improve 13%, feedstuff-meat ratio improves 4%, and 70%, one broiler chicken of dead mortality decline is increased income 0.6 yuan.
Above-described embodiment is only explanation technical conceive of the present invention and advantage; the present invention also can have other variation; as well known to the skilled person; above-described embodiment only plays the exemplary role in foregoing invention protection domain; for those of ordinary skills; in the protection domain limiting in the present invention, also have a lot of conventional distortion and other embodiment, these distortion and embodiment are by within the protection domain awaiting the reply in the present invention.

Claims (3)

1. for regulating and controlling to repair a feed addictive for Intestine of Broiler, it is characterized in that the component that contains following weight portion: sodium butyrate 20~40, methyl butyrate 90~110, clostridium butyricum 90~110, silica 60~80, modified potato starch 70~80.
2. according to claim 1 for regulating and controlling to repair the feed addictive of Intestine of Broiler, it is characterized in that the component that contains following weight portion: sodium butyrate 30, methyl butyrate 100, clostridium butyricum 100, silica 70, modified potato starch 75.
3. prepare as described in claim as arbitrary in claim 1 or 2 for regulating and controlling to repair the method for feed addictive for Intestine of Broiler, it is characterized in that, comprise the following steps:
(1) take methyl butyrate, sodium butyrate and the silica of recipe quantity, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) modified potato starch of step (1) gained mixture and recipe quantity is made to the fine granularity material of the spray-dried rear formation 0.2~0.5mm of wall material, again fine granularity material is fully mixed with the clostridium butyricum of recipe quantity, obtain of the present invention for regulating and controlling to repair the feed addictive of Intestine of Broiler.
CN201410195427.1A 2014-05-09 2014-05-09 A kind of for regulating and controlling to repair feed addictive of Intestine of Broiler and preparation method thereof Expired - Fee Related CN103931954B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104585509A (en) * 2015-02-03 2015-05-06 广东绿生源饲料科技有限公司 Forage-use granular sodium butyrate and preparation method thereof
CN105746905A (en) * 2016-03-01 2016-07-13 湖南晶天科技实业有限公司 Feed additive and preparation method thereof
CN109566863A (en) * 2019-01-18 2019-04-05 湖北华扬科技发展有限公司 Feed addictive and its preparation method and application

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101513222A (en) * 2009-02-18 2009-08-26 麦仑(厦门)生物科技有限公司 Feeding acidifier prepared by emulsifying technology and preparing method thereof
CN102805266A (en) * 2012-08-21 2012-12-05 山东新希望六和集团有限公司 Feed for improving digestive and immunologic ability of chicken

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN101513222A (en) * 2009-02-18 2009-08-26 麦仑(厦门)生物科技有限公司 Feeding acidifier prepared by emulsifying technology and preparing method thereof
CN102805266A (en) * 2012-08-21 2012-12-05 山东新希望六和集团有限公司 Feed for improving digestive and immunologic ability of chicken

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104585509A (en) * 2015-02-03 2015-05-06 广东绿生源饲料科技有限公司 Forage-use granular sodium butyrate and preparation method thereof
CN105746905A (en) * 2016-03-01 2016-07-13 湖南晶天科技实业有限公司 Feed additive and preparation method thereof
CN109566863A (en) * 2019-01-18 2019-04-05 湖北华扬科技发展有限公司 Feed addictive and its preparation method and application

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