CN103919976A - Traditional Chinese medicine composition for treating thromboangiitis obliterans and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating thromboangiitis obliterans and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating thromboangiitis obliterans and a preparation method thereof. The composition comprises the following raw medicinal materials: 40-60 parts by weight of golden-rod, 10-30 parts by weight of wartwort, 70-90 parts by weight of fistular onion stalk, 40-60 parts by weight of pubescent holly root, 70-90 parts by weight of raw rhubarb powder, 90-110 parts by weight of red phaseolus beans, 10-30 parts by weight of folium artemisise argyi, 15-35 parts by weight of chrysanthemum indicum, 20-40 parts by weight of licorice powder, 40-60 parts by weight of indian strawberry, 5-25 parts by weight of beautiful sweetgum fruit, 5-25 parts by weight of castor beans, 30-50 parts by weight of garden burnet, 190-210 parts by weight of honey and 20-40 parts by weight of herba chenopodii serotini. The traditional Chinese medicine composition for treating thromboangiitis obliterans has an obvious curative effect, allows fast effect and is low in cost and convenient to use.
Description
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of Chinese medicine composition for the treatment of thromboangiitis obliterans and preparation method thereof.
Background technology
Thromboangiitis obliterans is in a kind of rare chronic recurrent, the segmental diseases associated with inflammation of small artery and vein, and lower limb are common.Its clinical manifestation is that suffering limb ischemia, pain, intermittent claudication, pulsation of foot dorsal artery weaken or disappearance and migration Superficial phlebitis, and severe patient has acra ulcer and necrosis.Be more common in person between twenty and fifty, be apt to occur in lower limb, suffering limb presents momentary or persistence is pale, cyanosis, have scorching hot and twinge, and when sick limb is sagging, color of the leather reddens, when upper act, bleach, and then toes numbness, Calf muscle pain, excites when walking, when rest, disappears; Often there is superficial phlebitis and edema in calf.When inspection, find that pulsation of foot dorsal artery weakens or disappears.Along with intermittent claudication and Raynaud phenomenon can appear in PD, night, the pain increased, toes sharp ache, skin cyanosis, so toe-end ulcer or gangrene and turn black, spread to proximal part gradually.
General medicine or the operative treatment thromboangiitis obliterans of adopting, the medicine that Drug therapy is used is generally as follows, dextran intravenous drip prolonged application that to adopt dextran-40 be 5000～20000 with molecular weight has hemorrhage possible, should not apply during with secondary infection acute period of expansion and ulcer gangrene; Vasodilation can be applied Tolazoline, nicotinic acid, Phenoxybenzamine Hydrochloride etc.; When antibiosis have local and systemic infection, select suitable antibiotic therapy; Glucocorticoid to state of an illness acute stage can consider application, every day oral prednisone or intravenous drip hydrocortisone; The obvious person of analgesic pain can select various analgesic, or with the sealing of procaine acupoint injection therapy, vein or femoral artery periphery seal, the topical therapeutics such as even feasible lumbar sympathetic ganglion block or peridural anesthesia are protected from infection to dry gangrene sterile dressing, and ulcer can newly be changed dressings in external rehabilitation.Operative treatment, through the non-operative treatment person of failing to respond to any medical treatment, feasible lumbar sympathectomy, great saphenous vein transplantation shunt or arterial thrombus inner membrance decollement.When after the limitation of acral necrosis border, under aseptic condition, expand wound, by necrotic tissue cleaning.Refer to that to forming (toe) hold gangrenous person, consider to cut and refer to (toe) art.
Summary of the invention
For this reason, the object of the present invention is to provide a kind of Chinese medicine composition for the treatment of thromboangiitis obliterans and preparation method thereof.
For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of thromboangiitis obliterans, the crude drug of described compositions consists of: Herba Solidaginis 40-60 weight portion, Herba Euphorbiae Helioscopiae 10-30 weight portion, Bulbus Allii Fistulosi 70-90 weight portion, Radix Ilicis Pubescentis 40-60 weight portion, rhubarb powder 70-90 weight portion, Semen Phaseoli 90-110 weight portion, Folium Artemisiae Argyi 10-30 weight portion, Herba Dendranthematis indici 15-35 weight portion, Radix Glycyrrhizae powder 20-40 weight portion, Herba Duchesneae Indicae 40-60 weight portion, Fructus Liquidambaris 5-25 weight portion, Semen Ricini 5-25 weight portion, Radix Sanguisorbae 30-50 weight portion, Mel 190-210 weight portion is with the sub-20-40 weight portion of Herba Chenopodii Serotini.
The Chinese medicine composition of described treatment thromboangiitis obliterans, the crude drug of described compositions consists of: Herba Solidaginis 50 weight portions, Herba Euphorbiae Helioscopiae 20 weight portions, Bulbus Allii Fistulosi 80 weight portions, Radix Ilicis Pubescentis 50 weight portions, rhubarb powder 80 weight portions, Semen Phaseoli 100 weight portions, Folium Artemisiae Argyi 20 weight portions, Herba Dendranthematis indici 25 weight portions, Radix Glycyrrhizae powder 30 weight portions, Herba Duchesneae Indicae 50 weight portions, Fructus Liquidambaris 15 weight portions, Semen Ricini 15 weight portions, Radix Sanguisorbae 40 weight portions, Mel 200 weight portions He Herba Chenopodii Serotini 30 weight portions.
The Chinese medicine composition of described treatment thromboangiitis obliterans, described Chinese medicine composition adds conventional adjuvant to make acceptable external preparation clinically according to common process.
The invention provides a kind of external preparation that adopts above-mentioned pharmaceutical composition to add conventional adjuvant to prepare according to common process.
Described external preparation comprises spray, liniment, unguentum, paste, lotion or patch.
A kind of method that the invention provides Chinese medicine composition of preparing described treatment thromboangiitis obliterans, the method comprises the steps:
(a) get Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini according to selected parts by weight, be ground into respectively after mixing or mix after fine powder and be ground into fine powder, sieving for standby;
(b) get above-mentioned fine powder, add conventional adjuvant to make acceptable spray, liniment, unguentum, paste, lotion or patch clinically according to common process.
A kind of method that the invention provides Chinese medicine composition of preparing described treatment thromboangiitis obliterans, the method comprises the steps:
(a) getting Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini according to selected parts by weight mixes, decoct with water, filter and merging filtrate, get supernatant concentration extractum;
(b) get described extractum, add conventional adjuvant to make acceptable spray, liniment, unguentum, paste, lotion or patch clinically according to common process.
A kind of method that the invention provides Chinese medicine composition of preparing described treatment thromboangiitis obliterans, the method comprises the steps:
Get the sub-mixed powder of Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel and Herba Chenopodii Serotini according to selected parts by weight and be broken into coarse powder, add ethanol extraction and obtain alcohol extract, concentrating under reduced pressure is except after alcohol, add conventional adjuvant, make acceptable spray, liniment, unguentum, paste, lotion or patch clinically according to common process.
The invention provides a kind of Chinese medicine composition being prepared by above-mentioned method.
The application of Chinese medicine composition described in the present invention also provides in the medicine of preparation treatment thromboangiitis obliterans
The Chinese medicine composition for the treatment of thromboangiitis obliterans of the present invention, aspect treatment thromboangiitis obliterans, there is significant therapeutic effect by choosing the sub Chinese medicine composition of making for crude drug of Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini, instant effect, expense is low, easy to use, clinical cure rate is up to 98.3%.
The clinical observation of experimental example traditional Chinese medicine composition for treating thromboangiitis obliterans of the present invention
1, data and method
Clinical data: the patient that the present invention suffers from thromboangiitis obliterans to 120 examples carries out clinical observation.
The evaluation criterion of clinical therapeutic efficacy is:
(1) clinical cure: original transference cure;
(2) effective: original symptom part disappears;
(3) take a turn for the better: original state of an illness alleviates to some extent;
(4) invalid: symptom and sign is unchanged.
Medication: get respectively paste prepared by spray prepared by embodiment 1 and embodiment 3 and be sprayed in right amount or be coated on patient's site of disease, every 15 days courses for the treatment of, every day 2 times.
2, therapeutic outcome
Use after the traditional Chinese medicine composition for treating prepared of the embodiment of the present invention 1 above-mentioned 60 routine patient 2-3 course for the treatment of, observe the therapeutic outcome of described 60 routine patients' thromboangiitis obliterans, wherein cure 57 examples, effective 1 example, improvement 2 examples, invalid 0 example, cure rate is 95%.
Use after the traditional Chinese medicine composition for treating prepared of the embodiment of the present invention 3 other 60 routine patient 2-3 course for the treatment of, observe the therapeutic outcome of 2-3 example patient's thromboangiitis obliterans, wherein cure 59 examples, effective 1 example, improvement 0 example, invalid 0 example, cure rate is 98.3%.
Toxic and side effects: after treatment finishes, check hematuria routine, stool, the heart, liver and the no abnormal change of renal function.After 3 months, above-mentioned case is paid a return visit, without patients with recurrent.
3, conclusion
(1) Chinese medicine composition of the present invention has significant therapeutic effect at aspects such as treatment thromboangiitis obliteranss, and its cure rate can reach 98.3%, short treating period, and instant effect, and have no side effect.
Detailed description of the invention
Embodiment 1 spray dosage form
The Chinese medicine composition of the treatment thromboangiitis obliterans of the present embodiment, its formula is as follows:
Herba Solidaginis 40g, Herba Euphorbiae Helioscopiae 30g, Bulbus Allii Fistulosi 70g, Radix Ilicis Pubescentis 60g, rhubarb powder 70g, Semen Phaseoli 110g, Folium Artemisiae Argyi 10g, Herba Dendranthematis indici 35g, Radix Glycyrrhizae powder 20g, Herba Duchesneae Indicae 60g, Fructus Liquidambaris 5g, Semen Ricini 25g, Radix Sanguisorbae 30g, Mel 210g He the sub-20g of Herba Chenopodii Serotini.
Described Chinese medicine composition is prepared into spray according to following steps:
(a) get Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini according to selected parts by weight, be ground into respectively after mixing or mix after fine powder and be ground into fine powder, cross 40 mesh sieves for subsequent use;
(b) get above-mentioned fine powder, add conventional adjuvant to make acceptable spray clinically according to common process.
Embodiment 2 liniment dosage forms
The Chinese medicine composition of the treatment thromboangiitis obliterans of the present embodiment, its formula is as follows:
Herba Solidaginis 60g, Herba Euphorbiae Helioscopiae 10g, Bulbus Allii Fistulosi 90g, Radix Ilicis Pubescentis 40g, rhubarb powder 90g, Semen Phaseoli 90g, Folium Artemisiae Argyi 30g, Herba Dendranthematis indici 15g, Radix Glycyrrhizae powder 40g, Herba Duchesneae Indicae 40g, Fructus Liquidambaris 25g, Semen Ricini 5g, Radix Sanguisorbae 50g, Mel 190g He the sub-40g of Herba Chenopodii Serotini.
Described Chinese medicine composition is prepared into liniment according to following steps:
(a) get Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini according to selected parts by weight, be ground into respectively after mixing or mix after fine powder and be ground into fine powder, cross 400 mesh sieves for subsequent use;
(b) get above-mentioned fine powder, add conventional adjuvant to make acceptable liniment clinically according to common process.
Embodiment 3 paste dosage forms
The Chinese medicine composition of the treatment thromboangiitis obliterans of the present embodiment, its formula is as follows:
Herba Solidaginis 50g, Herba Euphorbiae Helioscopiae 20g, Bulbus Allii Fistulosi 80g, Radix Ilicis Pubescentis 50g, rhubarb powder 80g, Semen Phaseoli 100g, Folium Artemisiae Argyi 20g, Herba Dendranthematis indici 25g, Radix Glycyrrhizae powder 30g, Herba Duchesneae Indicae 50g, Fructus Liquidambaris 15g, Semen Ricini 15g, Radix Sanguisorbae 40g, Mel 200g He the sub-30g of Herba Chenopodii Serotini.
Described Chinese medicine composition is prepared into paste according to following steps:
(a) get Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini according to selected parts by weight, be ground into respectively after mixing or mix after fine powder and be ground into fine powder, cross 200 mesh sieves for subsequent use;
(b) get above-mentioned fine powder, add conventional adjuvant to make acceptable paste clinically according to common process.
Embodiment 4 unguentum dosage forms
The Chinese medicine composition of the treatment thromboangiitis obliterans of the present embodiment, its formula is as follows:
Herba Solidaginis 45g, Herba Euphorbiae Helioscopiae 25g, Bulbus Allii Fistulosi 75g, Radix Ilicis Pubescentis 55g, rhubarb powder 75g, Semen Phaseoli 105g, Folium Artemisiae Argyi 15g, Herba Dendranthematis indici 30g, Radix Glycyrrhizae powder 25g, Herba Duchesneae Indicae 55g, Fructus Liquidambaris 10g, Semen Ricini 20g, Radix Sanguisorbae 35g, Mel 205g He the sub-25g of Herba Chenopodii Serotini.
Described Chinese medicine composition is prepared into unguentum according to following steps:
(a) getting Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini according to selected parts by weight mixes, decoct with water secondary, add for the first time the water of 8 times of drug weight, decoct 2.5 hours, add for the second time 6 times of water gagings, decoct 2 hours, filter, merging filtrate, hold over night, gets the extractum that supernatant concentration to 60 DEG C relative density is 1.2-1.25;
(b) get described extractum, add conventional adjuvant to make acceptable unguentum clinically according to common process.
Embodiment 5 patch dosage forms
The Chinese medicine composition of the treatment thromboangiitis obliterans of the present embodiment, its formula is as follows:
Herba Solidaginis 55g, Herba Euphorbiae Helioscopiae 15g, Bulbus Allii Fistulosi 85g, Radix Ilicis Pubescentis 45g, rhubarb powder 85g, Semen Phaseoli 95g, Folium Artemisiae Argyi 25g, Herba Dendranthematis indici 20g, Radix Glycyrrhizae powder 35g, Herba Duchesneae Indicae 45g, Fructus Liquidambaris 20g, Semen Ricini 10g, Radix Sanguisorbae 45g, Mel 195g He the sub-35g of Herba Chenopodii Serotini.
Described Chinese medicine composition is prepared into patch according to following steps:
(a) getting Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini according to selected parts by weight mixes, decoct with water secondary, add for the first time the water of 12 times of drug weight, decoct 1.5 hours, add for the second time 10 times of water gagings, decoct 1 hour, filter, merging filtrate, hold over night, gets the extractum that supernatant concentration to 60 DEG C relative density is 1.2-1.25;
(b) get described extractum, add conventional adjuvant to make acceptable patch clinically according to common process.
Embodiment 6 lotion dosage forms
The Chinese medicine composition of the treatment thromboangiitis obliterans of the present embodiment, its formula is as follows:
Herba Solidaginis 48g, Herba Euphorbiae Helioscopiae 23g, Bulbus Allii Fistulosi 76g, Radix Ilicis Pubescentis 51g, rhubarb powder 79g, Semen Phaseoli 103g, Folium Artemisiae Argyi 17g, Herba Dendranthematis indici 26g, Radix Glycyrrhizae powder 28g, Herba Duchesneae Indicae 53g, Fructus Liquidambaris 10g, Semen Ricini 18g, Radix Sanguisorbae 42g, Mel 199g He the sub-32g of Herba Chenopodii Serotini.
Described Chinese medicine composition is prepared into lotion according to following steps:
Get the sub-mixed powder of Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel and Herba Chenopodii Serotini according to selected parts by weight and be broken into coarse powder, add the 55-75% ethanol of 4 times of drug weight, flood after 48 hours, it is 30 DEG C～40 DEG C that medicine liquid heating is kept to fluid temperature, forced circulation 3-4 hour, filters, and obtains alcohol extract, add conventional adjuvant, make acceptable lotion clinically according to common process.
Embodiment 7 paste dosage forms
The Chinese medicine composition of the treatment thromboangiitis obliterans of the present embodiment, its formula is as follows:
Herba Solidaginis 53g, Herba Euphorbiae Helioscopiae 13g, Bulbus Allii Fistulosi 84g, Radix Ilicis Pubescentis 47g, rhubarb powder 81g, Semen Phaseoli 98g, Folium Artemisiae Argyi 22g, Herba Dendranthematis indici 28g, Radix Glycyrrhizae powder 30g, Herba Duchesneae Indicae 58g, Fructus Liquidambaris 9g, Semen Ricini 21g, Radix Sanguisorbae 46g, Mel 198g He the sub-33g of Herba Chenopodii Serotini.
Described Chinese medicine composition is prepared into paste according to following steps:
Get the sub-mixed powder of Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel and Herba Chenopodii Serotini according to selected parts by weight and be broken into coarse powder, add the 55-75% ethanol of 12 times of drug weight, flood after 12 hours, it is 30 DEG C～40 DEG C that medicine liquid heating is kept to fluid temperature, forced circulation 3-4 hour, filters, and obtains alcohol extract, add conventional adjuvant, make acceptable paste clinically according to common process.
Obviously, above-described embodiment is only for example is clearly described, and the not restriction to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here without also giving exhaustive to all embodiments.And the apparent variation of being extended out thus or variation are still among the protection domain in the invention.
Claims (10)
1. treat the Chinese medicine composition of thromboangiitis obliterans for one kind, it is characterized in that, the crude drug of described compositions consists of: Herba Solidaginis 40-60 weight portion, Herba Euphorbiae Helioscopiae 10-30 weight portion, Bulbus Allii Fistulosi 70-90 weight portion, Radix Ilicis Pubescentis 40-60 weight portion, rhubarb powder 70-90 weight portion, Semen Phaseoli 90-110 weight portion, Folium Artemisiae Argyi 10-30 weight portion, Herba Dendranthematis indici 15-35 weight portion, Radix Glycyrrhizae powder 20-40 weight portion, Herba Duchesneae Indicae 40-60 weight portion, Fructus Liquidambaris 5-25 weight portion, Semen Ricini 5-25 weight portion, Radix Sanguisorbae 30-50 weight portion, Mel 190-210 weight portion is with the sub-20-40 weight portion of Herba Chenopodii Serotini.
2. the Chinese medicine composition for the treatment of thromboangiitis obliterans according to claim 1, it is characterized in that, the crude drug of described compositions consists of: Herba Solidaginis 50 weight portions, Herba Euphorbiae Helioscopiae 20 weight portions, Bulbus Allii Fistulosi 80 weight portions, Radix Ilicis Pubescentis 50 weight portions, rhubarb powder 80 weight portions, Semen Phaseoli 100 weight portions, Folium Artemisiae Argyi 20 weight portions, Herba Dendranthematis indici 25 weight portions, Radix Glycyrrhizae powder 30 weight portions, Herba Duchesneae Indicae 50 weight portions, Fructus Liquidambaris 15 weight portions, Semen Ricini 15 weight portions, Radix Sanguisorbae 40 weight portions, Mel 200 weight portions He Herba Chenopodii Serotini 30 weight portions.
3. the Chinese medicine composition for the treatment of thromboangiitis obliterans according to claim 1 and 2, is characterized in that, described Chinese medicine composition adds conventional adjuvant to make acceptable external preparation clinically according to common process.
4. the external preparation that adopts the arbitrary described pharmaceutical composition of claim 1-3 to add conventional adjuvant to prepare according to common process.
5. external preparation according to claim 4, is characterized in that, described external preparation comprises spray, liniment, unguentum, paste, lotion or patch.
6. prepare as arbitrary in claim 1-3 as described in the method for Chinese medicine composition for the treatment of thromboangiitis obliterans, it is characterized in that, the method comprises the steps:
(a) get Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini according to selected parts by weight, be ground into respectively after mixing or mix after fine powder and be ground into fine powder, sieving for standby;
(b) get above-mentioned fine powder, add conventional adjuvant to make acceptable spray, liniment, unguentum, paste, lotion or patch clinically according to common process.
7. prepare as arbitrary in claim 1-3 as described in the method for Chinese medicine composition for the treatment of thromboangiitis obliterans, it is characterized in that, the method comprises the steps:
(a) getting Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel He Herba Chenopodii Serotini according to selected parts by weight mixes, decoct with water, filter and merging filtrate, get supernatant concentration extractum;
(b) get described extractum, add conventional adjuvant to make acceptable spray, liniment, unguentum, paste, lotion or patch clinically according to common process.
8. prepare as arbitrary in claim 1-3 as described in the method for Chinese medicine composition for the treatment of thromboangiitis obliterans, it is characterized in that, the method comprises the steps:
Get the sub-mixed powder of Herba Solidaginis, Herba Euphorbiae Helioscopiae, Bulbus Allii Fistulosi, Radix Ilicis Pubescentis, rhubarb powder, Semen Phaseoli, Folium Artemisiae Argyi, Herba Dendranthematis indici, Radix Glycyrrhizae powder, Herba Duchesneae Indicae, Fructus Liquidambaris, Semen Ricini, Radix Sanguisorbae, Mel and Herba Chenopodii Serotini according to selected parts by weight and be broken into coarse powder, add ethanol extraction and obtain alcohol extract, concentrating under reduced pressure is except after alcohol, add conventional adjuvant, make acceptable spray, liniment, unguentum, paste, lotion or patch clinically according to common process.
9. the Chinese medicine composition preparing according to the arbitrary described method of claim 6-8.
10. according to claim 1-3 or 9 application of arbitrary described Chinese medicine composition in the medicine of preparation treatment thromboangiitis obliterans.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101028358A (en) * | 2007-04-04 | 2007-09-05 | 王爱华 | Oral Chinese medicinal composition for treating ribbon bleb |
| CN101244221A (en) * | 2007-02-13 | 2008-08-20 | 汪建国 | Composition for external application and preparation method |
| CN101507771A (en) * | 2008-09-10 | 2009-08-19 | 郑奎 | Burn scald rehabilitation powder |
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2014
- 2014-04-16 CN CN201410154271.2A patent/CN103919976A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101244221A (en) * | 2007-02-13 | 2008-08-20 | 汪建国 | Composition for external application and preparation method |
| CN101028358A (en) * | 2007-04-04 | 2007-09-05 | 王爱华 | Oral Chinese medicinal composition for treating ribbon bleb |
| CN101507771A (en) * | 2008-09-10 | 2009-08-19 | 郑奎 | Burn scald rehabilitation powder |
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Application publication date: 20140716 |
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