CN103877499A

CN103877499A - Chinese herbal preparation for treating tumors and preparation method thereof

Info

Publication number: CN103877499A
Application number: CN201410095153.9A
Authority: CN
Inventors: 张玉珍; 万光瑞
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-03-12
Filing date: 2014-03-12
Publication date: 2014-06-25

Abstract

The invention belongs to a Chinese herbal preparation for treating tumors and a preparation method thereof. The Chinese herbal preparation comprises a primary material and auxiliary materials, wherein the primary material is prepared from the following materials in parts by weight: 1-60 parts of ginsengs, 1-180 parts of codonopsis pilosula, 1-120 parts of lucid ganoderma, 1-120 parts of coriolus versicolor, 1-120 parts of herba epimedii, 1-120 parts of polygonum cuspidatum, 0.01-6 parts of astaxanthin powder, 1-120 parts of Chinese angelica, 1-90 parts of donkey-hide gelatin, 1-90 parts of vinegar turtles, 1-90 parts of sanguisorba officinalis, 1-90 parts of radix curcuma, 1-90 parts of sweet wormwood, 1-90 parts of sculellaria barbata, 1-90 parts of agrimonia pilosa ledeb, 1-30 parts of silybum marianum extract powder, 1-150 parts of oyster shell powder, 1-150 parts of radish seed powder, 1-90 parts of earthworm powder, 1-90 parts of fructus amomi, 1-60 parts of cinnamon and 720-7200 parts of water. The Chinese herbal preparation has effects of warming and enforcing qi and blood, disinfecting and inducing decomposition of calculi, increasing appetite, enhancing immunity, inducing dieresis and relaxing the bowels.

Description

Chinese medicine preparation for the treatment of tumor and preparation method thereof

Technical field

The invention belongs to medical technical field, be specifically related to a kind of safe and efficient, Chinese medicine preparation of the treatment tumor of the stable and right supporting anticancer of Quality Control and preparation method thereof.

Background technology

Along with aged tendency of population, the change of environmental pollution and living habit, whole world cancer morbidity presents continuous ascendant trend.Cancer in China patient has exceeded 2,000,000 people now every year, though expend several 10,000,000,000 yuan, still has 3/4 approximately more than 150 ten thousand people to be taken away valuable life.At present, three large measures of whole world treatment cancer: operation, chemotherapy and radiation, the negative and positive of all exhausting rapidly human body, reduce the metabolism of human body, shorten patient's life, are usually to pay through the nose to accelerate patient death.This must make medical profession anxious, and society is bitterly disappointed, and family members are distressed.The whole world is every year with the cancer therapy drug of approximately 48,000,000,000 dollars according to statistics, the cancer therapy drug portion that pure natural is relatively nontoxic is much smaller, add that many cancerous protuberance patients take merely pure natural or coordinate operation, chemotherapy and radiation, that patients ' lives obviously extends, quality of life obviously improves, and impels the relatively nontoxic cancer therapy drug of exploitation pure natural to become the important problem in the whole world.The existing Traditional Chinese Drug Anticancer composite preparation of China, application has clinically obtained certain curative effect, but more or containing toxic herb with bitter cold Chinese medicine, has weakening patient appetite, injuring normal cell, occurs the problems such as poor appetite asthenia, pessimism.

Summary of the invention

The object of the invention is to overcome defect of the prior art, and it is dialectical to provide one to follow traditional Chinese medical science entirety, according to modern medicine tumor invasion mechanism, there is benefiting qi and nourishing blood, anticancerization knot, increase appetite, strengthen immunity, diuresis relieving constipation, Chinese medicine preparation of the treatment tumor of safety non-toxic and right supporting anticancer and preparation method thereof.

The object of the present invention is achieved like this: this Chinese medicine preparation comprises major ingredient and adjuvant, major ingredient comprises that following raw materials according is formulated according to parts by weight: 1～60 part of Radix Ginseng, 1～180 part of Radix Codonopsis, 1～120 part of Ganoderma, 1～120 part of Coriolous Dersicolor (Fr.) Quel, 1～120 part of Herba Epimedii, 1～120 part of Rhizoma Polygoni Cuspidati, 0.01～6 part, astaxanthin powder, 1～120 part of Radix Angelicae Sinensis, 1～90 part, Colla Corii Asini, 1～90 part of Carapax Trionycis (processed with vinegar), 1～90 part of Radix Sanguisorbae, 1～90 part, Rhizoma Curcumae Longae, 1～90 part of Herba Artemisiae Annuae, 1～90 part of Herba Scutellariae Barbatae, 1～90 part of Herba Agrimoniae, 1～30 part, Herba Silybi mariani extract powder, 1～150 part of Concha Ostreae powder, 1～150 part, Radish seed powder, 1～90 part of Pheretima powder, 1～90 part of Fructus Amomi, 720～7200 parts, 1～60 part of Cortex Cinnamomi and water, adjuvant comprises that following raw materials according is formulated according to parts by weight: 1～300 part of 1～300 part of oligofructose and white sugar.

A preparation method for the treatment of the Chinese medicine preparation of tumor, comprises the steps:

Step 1: get the raw materials ready: Radix Ginseng, Radix Codonopsis, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Herba Epimedii, Rhizoma Polygoni Cuspidati, astaxanthin powder, Radix Angelicae Sinensis, Colla Corii Asini, Carapax Trionycis (processed with vinegar), Radix Sanguisorbae, Rhizoma Curcumae Longae, Herba Artemisiae Annuae, Herba Scutellariae Barbatae, Herba Agrimoniae, Herba Silybi mariani extract powder, Concha Ostreae powder, Radish seed powder, Pheretima powder, Fructus Amomi, Cortex Cinnamomi, oligofructose and white sugar; Above-mentioned raw materials is got ready in the rear environment that is positioned over respectively 5～15 ℃ and is preserved;

Step 2: by Radix Ginseng, Radix Codonopsis, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Herba Epimedii, Rhizoma Polygoni Cuspidati, Radix Angelicae Sinensis, Radix Sanguisorbae, Carapax Trionycis (processed with vinegar), Cortex Cinnamomi, Fructus Amomi and Rhizoma Curcumae Longae are put into the first silk bag;

Step 3: will add water in the bucket of boiling medicine of the Traditional Chinese medicine decocting packaging integrated machine that has national quality to authenticate;

Step 4: the first silk bag in step 2 is put into step 3 and add the bucket of boiling medicine of water to soak after 6～8h, decoct 1h;

Step 5: by Herba Scutellariae Barbatae, Herba Artemisiae Annuae and Herba Agrimoniae are put into the second silk bag;

Step 6: the bucket of boiling medicine of the second silk bag in step 5 being put into step 4 decocts 40min together with the first silk bag, takes out the first silk bag and the second silk bag after decocting;

Step 7: by Herba Silybi mariani extract powder, Concha Ostreae powder, Radish seed powder, astaxanthin powder and Pheretima powder pack in the 3rd silk bag;

Step 8: the 3rd silk bag in step 7 is put into step 6 and taken out the bucket of boiling medicine of the first silk bag and the second silk bag, little fire decocts 10min;

Step 9: medium and small step 8 fire is decocted in the bucket of boiling medicine after 10min and adds oligofructose, and white sugar and chopping are also soaked the Colla Corii Asini after 4h, and big fire decocts, and stir on decoction limit, limit, makes mixed liquor rise to 106 ℃ in 20min, i.e. concentrated termination;

Step 10: by after concentrated termination in step 9, open the bagging system of the Traditional Chinese medicine decocting packaging integrated machine that has national quality authentication, carry out aseptic subpackaged, sealing, be up to the standards, labelled, be finished product.

The first silk bag in described step 2, the 3rd silk bag in the second silk bag and step 7 in step 5 is 150 order silk bags.The every bag of capacity arranging in bagging system in described step 10 is 100～300ml.Finished product warehouse-in in described step 10 is also preserved under the environment of 5～15 ℃.

A kind of Chinese medicine preparation for the treatment of tumor, this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 3400 parts, 20 parts of Radix Ginsengs, 50 parts of Radix Codonopsis, 30 parts of Ganodermas, 20 parts of Coriolous Dersicolor (Fr.) Quel, 20 parts of Herba Epimedii, 20 parts of Rhizoma Polygoni Cuspidati, 0.5 part, astaxanthin powder, 15 parts of Radix Angelicae Sinensis, 20 parts, Colla Corii Asini, 20 parts of Carapax Trionycis (processed with vinegar), 15 parts of Radix Sanguisorbaes, 15 parts, Rhizoma Curcumae Longae, 9 parts of Herba Artemisiae Annuaes, 20 parts of Herba Scutellariae Barbataes, 9 parts of Herba Agrimoniaes, 15 parts, Herba Silybi mariani extract powder, 20 parts of Concha Ostreae powder, 20 parts, Radish seed powder, 15 parts of Pheretima powder, 12 parts of Fructus Amomis, 15 parts of Cortex Cinnamomis and water; Adjuvant comprises that following raw materials according is formulated according to parts by weight: 100 parts of 200 parts of oligofructoses and white sugars; The preparation method of this treatment tumor Chinese medicine preparation comprises the steps:

Step 1: get the raw materials ready: Radix Ginseng, Radix Codonopsis, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Herba Epimedii, Rhizoma Polygoni Cuspidati, astaxanthin powder, Radix Angelicae Sinensis, Colla Corii Asini, Carapax Trionycis (processed with vinegar), Radix Sanguisorbae, Rhizoma Curcumae Longae, Herba Artemisiae Annuae, Herba Scutellariae Barbatae, Herba Agrimoniae, Herba Silybi mariani extract powder, Concha Ostreae powder, Radish seed powder, Pheretima powder, Fructus Amomi, Cortex Cinnamomi, oligofructose and white sugar; Above-mentioned raw materials is got ready in the rear environment that is positioned over respectively 7 ℃ and is preserved;

Step 4: the first silk bag in step 2 is put into step 3 and add the bucket of boiling medicine of water to soak after 6.5h, decoct 1h;

Step 10: by after concentrated termination in step 9, open the bagging system of the Traditional Chinese medicine decocting packaging integrated machine that has national quality authentication, carry out aseptic subpackaged, sealing, be up to the standards, labelled, be finished product;

The first silk bag in described step 2, the 3rd silk bag in the second silk bag and step 7 in step 5 is 150 order silk bags; The every bag of capacity arranging in bagging system in described step 10 is 120ml; Finished product warehouse-in in described step 10 is also preserved under the environment of 7 ℃.

A kind of Chinese medicine preparation for the treatment of tumor, this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 2300 parts, 18 parts of Radix Ginsengs, 30 parts of Radix Codonopsis, 20 parts of Ganodermas, 10 parts of Coriolous Dersicolor (Fr.) Quel, 15 parts of Herba Epimedii, 15 parts of Rhizoma Polygoni Cuspidati, 0.4 part, astaxanthin powder, 12 parts of Radix Angelicae Sinensis, 12 parts, Colla Corii Asini, 12 parts of Carapax Trionycis (processed with vinegar), 12 parts of Radix Sanguisorbaes, 12 parts, Rhizoma Curcumae Longae, 9 parts of Herba Artemisiae Annuaes, 15 parts of Herba Scutellariae Barbataes, 9 parts of Herba Agrimoniaes, 3 parts, Herba Silybi mariani extract powder, 15 parts of Concha Ostreae powder, 15 parts, Radish seed powder, 12 parts of Pheretima powder, 9 parts of Fructus Amomis, 9 parts of Cortex Cinnamomis and water; Adjuvant comprises that following raw materials according is formulated according to parts by weight: 400 parts of 200 parts of oligofructoses and white sugars; The preparation method of this treatment tumor Chinese medicine preparation comprises the steps:

Step 1: get the raw materials ready: Radix Ginseng, Radix Codonopsis, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Herba Epimedii, Rhizoma Polygoni Cuspidati, astaxanthin powder, Radix Angelicae Sinensis, Colla Corii Asini, Carapax Trionycis (processed with vinegar), Radix Sanguisorbae, Rhizoma Curcumae Longae, Herba Artemisiae Annuae, Herba Scutellariae Barbatae, Herba Agrimoniae, Herba Silybi mariani extract powder, Concha Ostreae powder, Radish seed powder, Pheretima powder, Fructus Amomi, Cortex Cinnamomi, oligofructose and white sugar; Above-mentioned raw materials is got ready in the rear environment that is positioned over respectively 13 ℃ and is preserved;

Step 4: the first silk bag in step 2 is put into step 3 and add the bucket of boiling medicine of water to soak after 7.6h, decoct lh;

The first silk bag in described step 2, the 3rd silk bag in the second silk bag and step 7 in step 5 is 150 order silk bags; The every bag of capacity arranging in bagging system in described step 10 is 240ml; Finished product warehouse-in in described step 10 is also preserved under the environment of 13 ℃.

A kind of Chinese medicine preparation for the treatment of tumor, this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 55 parts of Radix Ginsengs, 136 parts of Radix Codonopsis, 117 parts of Ganodermas, 108 parts of Coriolous Dersicolor (Fr.) Quel, 112 parts of Herba Epimedii, 112 parts of Rhizoma Polygoni Cuspidati, 0.06 part, astaxanthin powder, 98 parts of Radix Angelicae Sinensis, 82.5 parts, Colla Corii Asini, 80 parts of Carapax Trionycis (processed with vinegar), 46 parts of Radix Sanguisorbaes, 87.7 parts, Rhizoma Curcumae Longae, 9 parts of Herba Artemisiae Annuaes, 50 parts of Herba Scutellariae Barbataes, 40 parts of Herba Agrimoniaes, 21.5 parts, Herba Silybi mariani extract powder, 136 parts of Concha Ostreae powder, 129 parts, Radish seed powder, 90 parts of Pheretima powder, 80 parts of Fructus Amomis, 3600 parts, 40 parts of Cortex Cinnamomis and water, adjuvant comprises that following raw materials according is formulated according to parts by weight: 150 parts of 200 parts of oligofructoses and white sugars, the preparation method of this treatment tumor Chinese medicine preparation comprises the steps:

Step 1: get the raw materials ready: Radix Ginseng, Radix Codonopsis, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Herba Epimedii, Rhizoma Polygoni Cuspidati, astaxanthin powder, Radix Angelicae Sinensis, Colla Corii Asini, Carapax Trionycis (processed with vinegar), Radix Sanguisorbae, Rhizoma Curcumae Longae, Herba Artemisiae Annuae, Herba Scutellariae Barbatae, Herba Agrimoniae, Herba Silybi mariani extract powder, Concha Ostreae powder, Radish seed powder, Pheretima powder, Fructus Amomi, Cortex Cinnamomi, oligofructose and white sugar; Above-mentioned raw materials is got ready in the rear environment that is positioned over respectively 9 ℃ and is preserved;

Step 4: the first silk bag in step 2 is put into step 3 and add the bucket of boiling medicine of water to soak after 7.2h, decoct 1 hour;

The first silk bag in described step 2, the 3rd silk bag in the second silk bag and step 7 in step 5 is 150 order silk bags; The every bag of capacity arranging in bagging system in described step 10 is 280ml; Finished product warehouse-in in described step 10 is also preserved under the environment of 9 ℃.

Clinical practice of the present invention: be applicable to cancerous protuberance patient; (1) disease see lack of appetite, become thin, weak; (2) coordinating operation, chemotherapy and radiation, is change, radiotherapy sensitization, prevents and treats cancerous protuberance and shifts; (3) hemocytes increasing, strengthens immunity, improves the quality of living.Consumption: each 50ml, the dilution or directly oral of heating, three times on the one, or follow the doctor's advice.

The present invention has temperature compensation QI and blood, and detoxicatingization knot, increases appetite, strengthens the effect of immunity and diuresis relieving constipation.Wherein, monarch drug: Radix Ginseng, Radix Codonopsis, Herba Epimedii, Cortex Cinnamomi, can invigorate the spleen and warm the kidney, recover brain and hypothalamic regulatory function, improve negative and positive and the metabolism of whole body, promote life quality; Ministerial drug: Radix Angelicae Sinensis, Colla Corii Asini, Radix Sanguisorbae, can blood-supplementing blood-nourishing, Carapax Trionycis, Ganoderma, Coriolous Dersicolor (Fr.) Quel, can strengthen immunity, and Rhizoma Polygoni Cuspidati and astaxanthin can anti-oxidation protection normal cells; Adjuvant drug: Herba Silybi mariani extract, Herba Scutellariae Barbatae, curcumin, Concha Ostreae, Radish seed, arteannuin, Herba Agrimoniae, Pheretima, there is anticancerization disease, hinder tumoricidal effect; Make medicine: Fructus Amomi and Radish seed, can increase appetite, Fructus Amomi and Pheretima have the effect of diuresis relieving constipation.

The present invention divides two parts from large aspect, and the one, righting: adopt Radix Ginseng, Radix Codonopsis, Herba Epimedii, Cortex Cinnamomi, Radix Angelicae Sinensis, Colla Corii Asini, Radix Sanguisorbae, Carapax Trionycis, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Rhizoma Polygoni Cuspidati, astaxanthin and Fructus Amomi; The 2nd, eliminating evil: to adopt Herba Silybi mariani extract, Herba Scutellariae Barbatae, curcumin, Concha Ostreae, Radish seed, arteannuin, Herba Agrimoniae and Pheretima.The concrete said medicine property of medicine in the present invention, function cures mainly with pharmacological action as follows respectively:

1, Radix Ginseng: sweet in the mouth, micro-hardship, slightly warm in nature.Return spleen, lung, the heart, kidney channel.[function cures mainly] strongly invigorating primordial QI, multiple arteries and veins is admittedly de-, the Fructus Alpiniae Oxyphyllae of calming the nerves, invigorating the spleen to benefit the lung, promotes the production of body fluid and nourishes blood.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, cough and asthma due to lung deficiency, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, deficiency of qi and blood, prolonged illness is empty wins, palpitation with fear insomnia, sexual impotence cold womb.[pharmacological action] 1. regulates central nervous system: Radix Ginseng can improve excitement and the process of inhibition of brain, makes it to tend to balance; Can improve mental and blue-collar ability, increase work efficiency.Promote the utilization of brain to energy matter, strengthen learning and memory ability.2. antitumor action: ginsenoside, ginseng polysaccharide, panacene's alcohols, panaxytiol and volatile oil material in Radix Ginseng have certain inhibitory action to tumor.3. the immunologic function of enhancing body: ginsenoside and ginseng polysaccharide are that Radix Ginseng regulates the active component of immunologic function, not only to normal person, and to the people of the immunologic hypofunction immunity function that is improved.Clinical experiment extends patient's life span as seen, and ameliorate tumor toxic and side effects of chemoradiotherapy is accelerated the reparation of damaged tissue.Leukocyte increasing, preventive radiotherapy leukopenia.Application ginseng polysaccharide have no side effect, safety, reliable.4. separately there are antioxidation, resisting fatigue, blood sugar lowering, improve the effects such as cardiac function.

2. Radix Codonopsis: sweet in the mouth, property is flat, enters spleen, lung two warps.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.[pharmacological action] 1. adjusts gastrointestinal motility, corrects the gastrointestinal motility dysfunction of pathological state.2. enhancing human body immunity: Turnover of Mouse Peritoneal Macrophages number is obviously increased, cell volume increases, and pseudopodium increases, the plurality of enzymes increased activity such as born of the same parents' nucleic acid in vivo, saccharide, ATP enzyme, succinate dehydrogenase, thereby strengthen its phagocytosis, promote mouse spleen lymphocyte DNA synthetic.3. strengthen hemopoietic function: can make RBC number raise, leukocyte count declines, and content of hemoglobin significantly increases.After excision animal spleen, effect obviously reduces, and shows that Radix Codonopsis has the spleen of impact to promote erythropoietic effect.4. there are anticoagulant, anti-stress, shock, heart tonifying, improve the effects such as blood flow change, Fructus Alpiniae Oxyphyllae, calmness, hypnosis.

3. Ganoderma: sweet in the mouth, property is flat, GUIXIN, liver, spleen, lung, the kidney Five Classics.[function cures mainly] cough due to consumptive disease, asthma insomnia, dyspepsia, malignant tumor etc.[pharmacological action] 1. antitumor action: Ganoderma is best immune function controlling agents and activator, it can significantly improve the immunologic function of body, strengthens patient's self anti-cancer, anti-cancer ability.Ganoderma can be by promoting the generation that waits endogenous cancer-resisting substance of interleukin～2, promote the phagocytic function of mononuclear phagocyte and the hematopoietic potential of human body, the anticancer such as leukocyte increasing are the preferred agents of antitumor, anti-cancer and assistant treating cancer.2. anti-aging effects: promote and adjustment immunologic function.Regulate metabolic balance, impel the nucleic acid of serum, liver and bone marrow and the biosynthesis of protein, effectively disease-resistant anti-aging; Ganoderan has significant plan superoxide dismutase (SOD) activity, can significantly remove the free radical that body produces, thereby stops the damage of radical pair body, prevents the peroxidating of fat body, Cell protection, delaying cell aging; Aobvious chopsticks promotes cell nuclear dna synthesis capability, and can increase the division algebraically of cell, delays the aging of body.3. protect the liver, the effect such as neurasthenia.

4. Coriolous Dersicolor (Fr.) Quel (Phaeoporus obliquus): sweet in the mouth, property is flat, GUIXIN, spleen, liver, kidney channel.[function cures mainly] invigorating spleen to remove dampness, heat-clearing and toxic substances removing.For jaundice due to damp-heat, hypochondriac pain, poor appetite, fatigue and weakness.[pharmacological action] 1. antitumaous effect: Coriolous Dersicolor (Fr.) Quel contains the various effective ingredient of beating back cancerous cell.The polysaccharide wherein extracting in prepared from coriolus versicolor mycelium and fermentation liquid all has extremely strong strong anticancer activity.Kinds of tumor cells (as mastocarcinoma, lip cancer, gastric cancer, parotid gland cancer, pulmonary carcinoma, skin carcinoma, rectal cancer, Huo Jinsi lymphatic cancer) is had to obvious inhibitory action, stomach cancer cell is had to antiproliferative effect and apoptosis-induced effect.2. immunity brings back to life: Coriolous Dersicolor (Fr.) Quel is a superstar who regulates immunity of organism, can strengthen immunocompetence, prevents cancer cell metastasis, diffusion, recurrence, alleviates the side effect of chemotherapy, actinotherapy and operation, strengthens the toleration of patient to radiotherapy, chemotherapy, promotion health.2. be the cleaning agent of blood and the alleviant of pain.Inonotue obliquus is taken through the many patient with advanced cancer that cannot have an operation, can improve gastrointestinal function, recovers patient appetite, treatment vomiting, diarrhoea, gastrointestinal dysfunction, and alleviating pain, puts on weight, and obtains with cancer struggle confidence and courage.3. can remove the free radical in body, Cell protection, the division algebraically of prolongation passage cell, promotes cell survival, promotes metabolism, effectively slow down aging.4. separately prevent and treat the effects such as diabetes, acquired immune deficiency syndrome (AIDS), resisting hypertension, defying age, antiinflammatory.

5. Herba Epimedii: acrid in the mouth, sweet, warm in nature.Return liver, kidney channel.[function cures mainly] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.[pharmacological action] 1. has the effect of androgen sample, and its effect is better than Gecko and Hippocampus.2. the impact on function of immune system, kidney deficiency human T-cell quantity, pouring rate of rotation, antibody, antigen and reticuloendothelial system phagocytic hypofunction, the kidney-reinforcing drug treatments such as Herba Epimedii all can improve.3. have the anabolic effect that promotes medullary cell DNA, what energy was good prevents and treats osteoporosis.4. suppress vasomotor center, expansion peripheral vessels, makes blood pressure drops, and myocardial ischemia in rats is had to certain protective role.

6. Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature, returns liver, gallbladder, lung meridian.[function cures mainly] dampness removing jaundice eliminating, heat-clearing and toxic substances removing, dissipating blood stasis relieves the pain, relieving cough and resolving phlegm.[pharmacological action] be the generation of Rhizoma Polygoni Cuspidati extract trans-resveratrol and cis-resveratrol. energy mutation prophylaxis of cancer 1.; 2. can effectively suppress the cellular activity relevant to the each process of cancer, 3 stages that occur for cancer---initial, hypertrophy and transfer have and suppress and even reverse effect.The one, suppress " initial ", reduce free radical and form, induction II phase medicine increases for enzyme, the effect of antagonism dioxin; The 2nd, suppress " enhancement ", suppress cyclooxygenase (COX), suppress catalase; Three suppress " development ", anticancer propagation, inducing cancer cell differentiation, cancer cell specific induction of apoptosis.Resveratrol is the inhibitor of protein tyrosine kinase PTK, and the Several Kinds of Malignancy cells such as breast carcinoma, gastric cancer, colon cancer, carcinoma of prostate, leukemia, ovarian cancer, skin carcinoma are all had to obvious inhibitory action.3. separately there is antioxidation, antiinflammatory, low blood viscosity, anti-platelet clotting, vasodilator, strengthens immunity, life lengthening and estrogen-like effects.

7. astaxanthin (astaxanthin): be natural algae source astaxanthin, the highest level product that class Hu Luosu is synthetic, is that the mankind find the antioxidant that nature is the strongest up to now, is described as " super VE ".Mainly be used in the cosmetics of super quality, field of health care food.Classified as new food resource by health ministry [defending No. 0011st, the new examination of food word (2007)].[pharmacological action]: 1. suppress tumor: research shows that astaxanthin can significantly suppress the initial stage canceration of chemicals inductions, has the effect of antiproliferative effect and reinforced immunological function to being exposed to epithelial cell in carcinogen, and this effect amount effect relationship.Therefore infer that astaxanthin has significant anticancer property.Astaxanthin can also be induced the transferring enzyme in liver, significantly suppresses mouse bladder cancer, rat oral cancer and colon cancer, gastric cancer, and its action effect is more more obvious than bata-carotene.Astaxanthin regulates cell-cell communication by changing membrane stability and gene expression quantity, thereby improves intercellular balanced capacity, maintains the normal function of cell.2. superpower antioxidation: be 550 times of vitamin E, 200 times of lycopene, are called as " super antioxidant ", can significantly suppress the attack of radical pair human cell membrane, protection normal cell.3. enhancing immunity: astaxanthin can obviously promote splenocyte to produce the ability of antibody, strengthen the effect of T cell, stimulate the generation of immunoglobulin in body, strengthen the release of mouse interleukin I and tumor necrosis factor, inducing tumor cell division apoptosis, acts on more much better than than bata-carotene and canthaxanthin.4. relieving sports fatigue, enhancing body energy metabolism, the effects such as antiinflammatory infection.

8. Radix Angelicae Sinensis: sweet in the mouth, pungent, bitter, warm in nature, return liver, the heart, spleen channel.[function cures mainly] enriches blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.[pharmacological action] 1. antitumor action: Radix Angelicae Sinensis polysaccharide is inhibited to the strain of kinds of tumors tumor, can obviously suppress tumor growth, increase macrophage number, strengthen its phagocytic function and splenocyte activity, obviously extend the animal survival phase, human leukemia cell line AB cell proliferation is had to obvious inhibitory action.2. blood tonification effect: Radix Angelicae Sinensis can promote bone marrow and splenocyte hemopoietic function.Significantly increase hemoglobin and RBC number.Increase spleen and thymus weightening finish.Promote the recovery of bone marrow and splenocyte hemopoietic function.Prevent thymus secondary atrophy.Improve animal dis motility rate.Increase spleen endogenous hemopoietic focus and form, improve bone marrow nucleated cell counting.3. antioxidation and anti-aging effects: Radix Angelicae Sinensis the tool active and Ca++ATP enzymatic activity of Superoxide dismutase disproportionation thing (SOD) that is significantly improved in cerebral cortex, reduce the content of lipofuscin (LPF) and lipid peroxide (LPO), when high dose, effect is more obvious, illustrates that Radix Angelicae Sinensis has anti-aging effects.4. the effect such as enhancing human body immunity, anticoagulant, ischemia resisting damage, calmness, hypnotic.

9. Radix Sanguisorbae: bitter in the mouth acid, cold in nature, nontoxic.[return through] liver; Lung; Kidney; Large intestine channel.[effect] cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore.[pharmacological action]: 1. promote hemopoietic: sanguisorbin can promote leukocyte, erythrocyte, hematoblastic generation, has hemopoietic facilitation.Sanguisorbin, by promoting proliferation of bone marrow cells, increases Numbers of Peripheral Blood Cells, especially makes erythrocyte and hematoblastic quantity increase.2. there is anti-tumor activity, can also reduce the granulocytopenia causing because of chemotherapy, prevent or alleviate the toxicity that chemotherapy causes.Acute toxicity test finds that its mouse stomach maximum dosage-feeding has no overt toxicity reaction, is expected to become efficient, low toxicity, inexpensive anti-cancer agent.3. antidiarrheal, hemostasis, antibacterial action.

10. Carapax Trionycis (processed with vinegar): salty in the mouth, cold nature, return liver, kidney channel.[function cures mainly] nourishing YIN for suppressing the hyperactive YANG, brings down a fever except steaming, hard masses softening and resolving.[pharmacological action] 1. antitumor action: Carapax Trionycis extracting solution has inhibitory action to mouse ascites sarcoma cell, hepatoma carcinoma cell and murine lung cancer cell growth in vitro.Carapax Trionycis polysaccharide may, by strengthening non-specific immunity and the cellular immune function of tumor-bearing mice, obviously suppress the growth of tumor-bearing mice tumor.Carapax Trionycis leachate can play inhibition growth to colon-cancer cell, reduce the metabolic activity of colon-cancer cell, damage or destroyed enterocyte structure of mitochondria, disturb cell function, affect the synthetic of the interior ATP of cell, in the time increasing Carapax Trionycis concentration, further destroyed nucleus, affect the synthetic of DNA, thereby suppressed colon-cancer cell propagation.2. strengthen immunization: Carapax Trionycis extract (TSWE) has antitumor, radioprotective and improves non-specific immunity and cellular immune function.Carapax Trionycis micropowders can improve mouse macrophage and phagocyte quantity.QINGHAOBIEJIATANG has regulating action to acute myeloid leukemia catabasis patient's immunologic function.3. have anti-liver, lung, renal fibrosis, anti-hypoxia, significantly increases Mouse Lactate Dehydrogenase (LDH) vigor, the metabolite of body while effectively removing strenuous exercise, generation and the elimination accelerating fatigue etc. of energy delay fatigue.

11. Colla Corii Asini: [pharmacological action] 1. blood tonification effect: depletion method causes that dog anemia proves that Colla Corii Asini has powerful blood tonification effect, and curative effect is better than chalybeate, and hemoglobin, packed cell volume significantly increase.Can make anemia rabbit hemoglobin, erythrocyte, leukocyte extremely significantly increase, platelet is also significantly increased.2. strengthen immunity: Colla Corii Asini can improve monocytic phagocytic function, resist the Cellular immunity suppression effect due to hydrocortisone, NK cell is had to facilitation, spleen is had to obvious effect of gain.The effects such as the 3. growth of resisting fatigue, anti-hypoxia, hypermnesis, promotion bacillus bifidus, promotion calcium absorption.

12. Herba Silybi mariani extract: Herba Silybi mariani bitter in the mouth, cool in nature, return liver, gallbladder meridian.[function cures mainly] heat-clearing and toxic substances removing, protects the liver and protects brain, function of gallbladder promoting, anti-X ray.For dampness-heat in the liver and gallbladder, hypochondriac pain, jaundice, cholelithiasis and chronic cough.2 kinds of main compositions of modern study Herba Silybi mariani containing silymarin and silibinin.[pharmacological action] 1. antitumor action: silymarin can effectively be removed free radical, resists various active oxygen oxidation guanines and forms 8～hydroxyl guanine, the tumor that causes DNA damage to cause, prevention and treatment malignant tumor.Skin carcinoma, carcinoma of prostate, breast tumor etc. are had to preventive and therapeutic effect.2. be free radical scavenger, energy anti peroxidation of lipid, has very strong scavenging action to alkoxy radical, and the ethyoxyl free radical that cytochrome metabolic activation is generated has stronger scavenging action.3. protect the liver and antiinflammatory action: Herba Silybi mariani flavone absorption of human body of new generation is good, rapid-action, bioavailability is high, can suppress epoxidase and lipoxygenase, promote intrahepatic fat transhipment and antioxidation, prevent that fat is to hepatocellular excessive infiltration.Natural safety, fat eliminating hepatoprotective, the damage of stablizing liver plasma membrane, the liver protecting and be not subject to harmful liver material such as ethanol, chemicals, repairs impaired hepatocyte, strengthens growth and the removing toxic substances functions of expelling toxin of normal liver cell.

13. Herba Scutellariae Barbataes: cold in nature, acrid in the mouth, hardship.[function cures mainly] heat-clearing and toxic substances removing, blood stasis dispelling diuresis.[pharmacological action] is 1. anticancer: Herba Scutellariae Barbatae has good anti-tumor activity, and curing mainly the gynecological tumors such as the digestive tract tumor such as primary hepatocarcinoma, pulmonary carcinoma and cervical cancer has good therapeutic effect.Its dominant mechanism is as follows: a strengthens stool body immunity.Inhibition tumor cell is escaped and growth.Herba Scutellariae Barbatae ethanol extract is to transplanted tumor (sarcoma S ₁₈₀with hepatocarcinoma H ₂₂) there is significant inhibitory action, promote splenocyte propagation, there is good dose-dependence.B promotes the release of storage calcium in tumor cell and the interior stream of the outer calcium ion of born of the same parents, significantly improves the concentration of intracellular free calcium, starts apoptosis program, inducing apoptosis of tumour cell.C Antimutagenesis.Herba Scutellariae Barbatae can be resisted the damaging action of cigarette coke tar condensation product to lymphocyte DNA significantly, protects lymphocytic DNA.D suppresses telomerase activation, and the anticancer prescription of the compositions such as Herba Scutellariae Barbatae has stronger inhibitory action to human colon cancer cell strain telomerase activation.E antioxidation, Herba Scutellariae Barbatae can suppress the damage of active oxygen DNA, and prophylaxis of tumours forms.Scutellaria Barbata D. Don Polysaccharides also has obvious scavenging action to negative oxygen-derived free radicals, and increases scavenging action enhancing with dosage.F suppresses tumor-blood-vessel growth effect, and Herba Scutellariae Barbatae can effectively suppress tumor-blood-vessel growth, and its mechanism may be expressed relevant with blocking-up endothelial cell migration, downward vegf protein.G has associating antitumaous effect.2. diuresis, antipyretic, protect the liver, antiinflammatory, anti-aging effects.

14. Rhizoma Curcumae Longaes: acrid in the mouth hardship, warm in nature.The circulation of qi promoting of [function cures mainly] removing blood stasis, dysmenorrhea relieves the pain.Sharp for the breast side of body, tumbling and swelling.[pharmacological action] 1. antitumor action: a curcumol has cytotoxicity to kinds of tumor cells, as people's gastric cancer SGC-7901 cell line, human esophagus cancer EC9706 cell, human liver cancer cell, human lung adenocarcinoma cell, human breast cancer cell etc., suppress core metabolism, nucleo-cytoplasmic ratio is diminished, inhibition tumor cell growth, kill cancerous cell, inducing apoptosis of tumour cell, but can raise human colon carcinoma SW ₄₈₀the expression of cell FasL mRNA, strengthens the invasive ability of colon cancer cell.B strengthens immunoreation, can see intensive small lymphocyte around cancerous cell in pathological section, has a large amount of hole cell tissue propagation in lymphatic sinusoid, and disclosing host in effective case has obvious immunoreation, suppresses invasion and metastasis of tumor.C antineoplastic vascular generates: curcumin is a species specificity angiogenesis inhibitor, reduces VEGF, HIF-1a, the expression of HIF-1a direct regulation and control VEGF gene, thereby containment endothelial cell proliferation and migration.The anti-leukocyte increasing of d, expression and the activity of increase interleukin, increase the generation of macrophage IL-1 and IL-8, the leukopenia that antagonism is caused by cyclophosphamide.E is radiotherapy sensitization, anti-mutation, the drug resistance of reverse artitumor multi.2. the effect such as antiinflammatory, antithrombotic, resisting pathogenic microbes.3. can pass through blood brain barrier, at the distribution of tumor tissues and its hetero-organization, without significant difference, its mainly elimination approach is renal excretion.

15. Herba Artemisiae Annuaes: bitter in the mouth, pungent, cold in nature.Return liver, gallbladder meridian, three warmers, kidney channel.[function cures mainly] expelling summer-heat, cut cruel, removing heat from blood, reducing the asthenic fever.[pharmacological action] 1. antitumor action: a inducing apoptosis of tumour cell, arteannuin is different to the direct killing effect of cell from 5-FU, but the cytotoxicity mediating by ferrous ion, inducing apoptosis of tumour cell, similar to its malaria mechanism.B Mediated by Free Radicals cytotoxicity, similar with poisoning plasmodium, the peroxide bridge cracking that the ferrous ion in tumor cell can catalysis arteannuin, produces a large amount of free radicals and ROS, destroy tumor cell membrane and cause intracellular matter to leak outside, thereby kill tumor cell.C suppresses angiogenesis.D increases Concurrent Chemoradiotherapy Sensitivity.The antitumor drug such as e and 5-FU, amycin have synergistic antitumor effect.2. antiinflammatory, parasiticide, antiviral, Antimalarial.

16. Concha Ostreaes: salty in the mouth, cold nature; Return liver, gallbladder, the calm convergence of kidney channel [function cures mainly], suppressing the hyperactive liver to relieve the wind syndrome.Treatment is dizzy, have a stomach-ache, gastric acid, just rare.[pharmacological action] 1. antitumor action: a improves host and exempts from main immunologic function, and particularly natural killer cell activity wherein suppresses the tumor cell proliferations such as pulmonary carcinoma, adenocarcinoma of stomach, rhinocarcinoma and grows by immune system, apoptosis-induced.B antioxidation, Concha Ostreae extract can make to have in cell the glutathion (GSH.) of anti-cancer and anti-aging function to breed 2 times, and can alleviate the side effect of the anticancer drugs, doxorubicin (ADM) with powerful anticancer activity to heart.2. promote body's immunity, anti-leukopenia.3. antithrombotic, antiulcer, enhancing eupepsy, reduce the effects such as capillary permeability.

17. Radish seeds: acrid in the mouth, sweet, property is flat, returns lung, spleen, stomach warp.[function cures mainly] de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm.Stop up and breath with cough for eating accumulation, abdominal distention, expectorant.[pharmacological action] 1. antitumor action: a Radish seed extract Sulforaphane can suppress the vigor of I phase enzyme-CYPs by covalent modification, prevents from that many Organic substances from activating to be combined and to bring out cancer with DNA for electrophilic compound.B activates the activity of II phase enzyme, and II phase enzyme (as NQ01, GST, UGT etc.) can be converted into low toxicity by electrophilic thing and be easy to the material of draining, and plays removing toxic substances and protective effect on cancer risk.C Sulforaphane can be reacted with GSH and albumen sulfydryl, activates Nrf2, and induction produces a series of II phase enzymes and antioxidase and reactive oxygen species.Due to II phase enzyme and antioxidase can be within a period of time sustainable existence, thereby the function of Sulforaphane can keep the longer time after it absorbs.D inducing apoptosis of tumour cell.Sulforaphane can suppress by mistake the activity of HDAC, activates p21 and Bax gene and carrys out cell death inducing.E inducing tumor cell Cycle Arrest: different cancerous cell is blocked in different times, comprise Go/G1 phase, G2/M phase and S phase.E suppresses neoplasm metastasis, suppresses the expression of blood vessel epithelial cell generation receptor KDR/flk-1 at transcriptional level, suppresses tumor growth.MMP plays pivotal role at the angiogenesis of tumor growth, invasion and attack, transfer and cancerous tissue.Sulforaphane can suppress by suppressing collagen matrices the aggressivity of oncocyte, and inhibition tumor cell shifts.2. regulate immunity: hemopoietic system, cell and humoral mediated immunity system are had to regulating action.Experiment in vitro can improve the natural killer cell activity of transplantation tumor animal, dissolve tumor cell, in another discovery Sulforaphane group metastatic tumor animal body, IL-2 and IFN-' Y increase, serum proinflammatory cytokine, as reductions such as IL-1p, IL-6, TNF-a, GM-CSF, prove that Sulforaphane has immunoregulatory effect.3. ultraviolet injury resistant, separates heavy metal poison, antiinflammatory, effect such as antibacterial grade.

18. Herba Agrimoniaes: bitter and puckery flavor, property are put down.Return stomach, liver, spleen, lung, large intestine channel.[function cures mainly] anticancer, the astringing to arrest bleeding that relieves internal heat, removing toxic substances dysentery relieving.[pharmacological action] 1. antitumaous effect: a can directly suppress hepatoma cell proliferation, liver cancer apoptosis reducing.Cervical cancer, adenocarcinoma of lung, breast carcinoma are all had to inhibitory action.B improves erythrocyte immune in serum and promotes factor active and reduce inhibitive factor activity, promotes NK cell and IL2 activity, reduces tumor necrosis factor (TNF) level, and performance antitumor, regulates the effect of immunity of organisms.C treats the kinds of tumors such as pulmonary carcinoma, hepatocarcinoma, gastric cancer, intestinal cancer clinically all obvious curative effects.E is 88.89% to osteoma pain effective percentage, is 56.78% to hepatocarcinoma, pulmonary carcinoma, breast carcinoma, nasopharyngeal carcinoma, esophageal carcinoma intestinal cancer, gastric cancer pain effective percentage.F improves the curative effect of radio-frequency (RF) therapy tumor, reduces residual tumor, reduces and shifts.G agrimonol extract (AP-M) energy cancer cell specific induction of apoptosis, cytotoxicity direct killing cancerous cell, antagonism carcinogen, adjusting host NK cell, TNF, IL2 and erythrocytic immune function, but bring into play the effect of killing kinds of tumors by number of ways, but wherein to kill digestive tract tumor as obvious.2. promote blood coagulation, blood sugar lowering, analgesia, the effect such as antibacterial.3. the half lethal dose of Herba Agrimoniae (LD50) 80g/kg is a kind of safer Chinese medicine.

19. Pheretimas: salty in the mouth, cold in nature.Return liver, spleen, urinary bladder channel.[function cures mainly] heat clearing away arresting convulsion, dredging collateral, clearing lung, relieving asthma, inducing diuresis for treating stranguria syndrome.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, and numb limbs and tense tendons,

Hemiplegia, dyspnea and cough due to lung-heat, edema oliguria.[pharmacological action] 1. antitumaous effect: Pheretima has obvious inhibitory action to murine sarcoma S180, not only tumor body obviously reduces, and can extend the life cycle of mice.To transplanted solid tumor H22, also there is obvious inhibitory action.Pheretima extract is worked in coordination with interleukin-22 (IL-2) and is suppressed S 180 Growth on Mice.Produce stronger radiation potentiation with 5-FU, radiation synergist AK123 use in conjunction, tumor killing effect is best.With combined with hyperthermia application, the inhibition of mouse entity tumor EMT6 is also had to obvious synergism.Pheretima extract antitumaous effect may be by improving body immunity and inhibition tumor cell growth.Tumor-bearing mice is after Stabilipan local irradiation, spleen weight, spleen number of nucleated cells, NK cytoactive, ADCC activity and board cell IL-2 activity are all subject to certain inhibition, but as add with the treatment of Pheretima extracting solution, have no any immunosuppressive action, even increase, prompting has certain facilitation to body's immunity.Mice gavages Pheretima extract every day, can make tail hemophagocyte chemiluminescent enhancement, recovers NK activity, improves T3, T4 and T4/T8, and pointing out it is a kind of immunostimulant.Accept radiocurable patient with esophageal carcinoma and take Pheretima extract 150mg, every day 2 times, can control patient's leukopenia, effect is better than immunostimulant punishment polyactin (polyactin A).Lotus tumor (S180) mice gavages Pheretima extract 100mg/kg every day, 7d can reduce lotus tumor and cause that fluorescence-causing substance content increases continuously, the excellent sweet fabk polypeptide of blood two-story valley (GR), catalase (CAT), the sweet peptide oxide of Gu You enzyme (GSH～Px) activity moving and superoxide dismutase (SOD) increase, and prompting Pheretima extract has the effect of removing free radical, anti peroxidation of lipid.2. refrigeration function: infective fever patient cooling effect is better than to aspirin (oral 0.3g) also effective to noninfectious fever, but effect appearance is more late, after taking medicine, 0.5～3h is effective, and 2～5h body temperature is down to normally.3. convulsion, calmness, relieving asthma, thrombolytic, anticoagulation and diuresis.

20. Fructus Amomis: acrid in the mouth, warm in nature.Return spleen channel, stomach warp, kidney channel.The appetizing of [function cures mainly] fragrance, warming spleen and stopping diarrha.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry.[pharmacological action] 1. digestive system effect: Fructus Amomi aqueous extract can make motilin (MTL) in blood plasma, gastric antrum and jejunum tissue, Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 (SP) content obviously increase, and digestive tract power significantly strengthens, promotes gastric emptying and intestinal transmission.In Fructus Amomi volatile oil, borneol acetate, by suppressing intestinal smooth muscle motion, produces antidiarrheal, analgesia, spasmolysis.Fructus Amomi can increase gastric mucosal blood flow, promotes the reparation of gastric mucosa injury.2. choleretic effect: Fructus Amomi ethanol extract has lasting choleretic effect, this and the pungent temperature of Fructus Amomi, return taste warp, appetite-stimulating indigestion-relieving, dispels distension and fullness in the abdomen, and strengthening the spleen and stomach is relevant.3. Fructus Amomi has remarkable inhibitory action to the caused peripheral leukocytes of cyclophosphamide, erythrocyte, worth reduction.Fructus Amomi has anti-artery thrombosis and anticoagulant effect, can also obviously reduce mouse antibodies number.Fructus Amomi can be used as tumor inhibitor.4. antioxidation, anticoagulant, antiinflammatory, enhancing immunization.

21. Cortex Cinnamomis: Cortex Cinnamomi acrid in the mouth, sweet, extremely hot in nature, GUIXIN, spleen, lung, kidney four warps.[function cures mainly] pain relieving is supporing yang, diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.[pharmacological action] 1. antitumor action: cinnamic acid is the hormone of regulating plant Growth of Cells and differentiation, but research in recent years is found cinnamic acid and can be suppressed the propagation of the cell lines such as people's glioblastoma multiforme, melanoma and the insensitive carcinoma of prostate of hormone, high-transfer human lung carcinoma cell malignant phenotype is had and reversed and anti-invasion effect, the differentiation that can induce human lung adenocarcinoma cell, human liver cancer cell, human promyelocytic leukemia cell etc. is a kind of natural differentiating inducer that various kinds of cell is had to differentiation.Mice long-term taking Cortex Cinnamomi aldehydes can delay the generation b41 of hepatocarcinoma; Cinnamic aldehyde can inhibition tumor cell propagation, its mechanism is cause reactive oxygen species (ROS) mediation mitochondrial membrane permeability change and impel cytochrome c release.2. the central nervous system hormonal system effect of unifying: cinnamon water extract can suppress cholesterol in the atrophy of thymus gland of dexamethasone yang deficiency mice and adrenal gland and raise; Two kinds of methanolic extracts can make the maximum binding capacity of rat kidney B mono-adrenoreceptor hyperfunction by normally changing into; Cortex Cinnamomi can be improved male rat plasma testosterone level and be reduced blood plasma trilute level, but does not affect plasma corticosterone level.Cinnamic aldehyde has analgesic activity, can resist the temperature decline that reserpine causes.3. Cortex Cinnamomi water extract can suppress reticuloendothelial system phagocytic function and antibody formation.But cinnaman but has the effect that strengthens reticuloendothelial system function, no matter lumbar injection still gavages the ability that can improve mouse macrophage and engulf carbon granule.Cinnamic aldehyde and derivant thereof are mainly that antiinflammatory action is brought into play in the generation by suppressing NO.

Zoopery: adopt MFC Mus source stomach cancer cell to go down to posterity and cultivate and cell counting, adjusting cell concentration is 107/ml, carries out back subcutaneous vaccination by 0.2ml/10g to mice.The mice of inoculation is divided into dosage group, high dose group of the present invention in blank group, positive Chinese medicine (Ai Di) matched group, positive Western medicine (cyclophosphamide) matched group, low dose group of the present invention, the present invention at random.Administration from inoculation second day, totally 4 weeks.Blank group normal saline every day gavage 0.2ml/10g, positive Chinese medicine (Ai Di) matched group carries out lumbar injection Ai Di by 0.15ml/10g every day; Positive Western medicine (cyclophosphamide) matched group weekly intraperitoneal injection once, each dosage is 1mg/10g; Mice gastric infusion every day of dosage group, high dose group of the present invention in low dose group of the present invention, the present invention, dosage is respectively 0.007ml/10g, 0.0225ml/10g, 0.07ml/10g.After 28 days, put to death mice, take off tumor tissues, weigh, calculated weight tumour inhibiting rate.Experimental result: respectively organize gastric cancer MFC tumor growth situation, dosage group < low dose group < blank of the present invention group in positive Chinese medicine (Ai Di) matched group of the heavy order of its tumor positive Western medicine (cyclophosphamide) matched group < high dose group < of the present invention < the present invention.Statistical analysis: positive Western medicine (cyclophosphamide) matched group has utmost point significant difference (P<0.001) compared with blank group, in low dose group of the present invention, the present invention, the tumor of dosage group, high dose group of the present invention, positive Chinese medicine (Ai Di) matched group weighs significant difference (P<0.01) compared with blank group.Calculate tumour inhibiting rate, the tumour inhibiting rate of positive Western medicine cyclophosphamide is the highest, can reach 54.3%; The tumour inhibiting rate of high, the middle dosage group of experiment Chinese medicine is respectively 45.1% and 41.5%, and positive Chinese medicine Ai Di tumour inhibiting rate is 42.5%.Prompting: anticancer experiment Chinese medicine has obvious anti-tumor activity, has in vivo the effect of stronger inhibition gastric cancer tumor growth.

Clinical research: clinical 32 routine cancer patients are taken health status summary sheet of the present invention:

In table, 32 routine cancer patients have 6 routine patients to take merely Traditional Chinese Drug Anticancer syrup of the present invention, operation+chemotherapy+take Traditional Chinese Drug Anticancer syrup 19 examples of the present invention, radiotherapy+Traditional Chinese Drug Anticancer syrup 5 examples of the present invention, operation+radiotherapy+Traditional Chinese Drug Anticancer syrup 2 examples of the present invention.By the treatment of 2 months, except 4 routine serious late cancer patients because of merge MOFE through short term therapy with regard to death, all the other patient health situations all take an evident turn for the better.The index observings such as RBC counting, Hb, WBC counting, CD4/CD8 ratio, NK cytoactive all have clear improvement.Take merely the present invention and adopt other Therapeutic Method to add the present invention and not yet carry out statistical analysis and comparison with the case of filing in the past, just overall observation and patient's reflection, taking this morbidity can obviously increase the confidence of patient's muscle power and existence.Accumulating at present case, after reaching some, then gathering, analyzing and report.

Tool of the present invention has the following advantages:

1. mend and attack the double principles of formulating prescriptions of executing.The present invention is the three phases for tumor invasion according to white wound brain regulation and control whole body yin-yang theory: first stage---" initial ", brain regulation and control whole body negative and positive are not normal, can not contain in time that the negative and positive of local organization cross Sheng, grow the whole body negative and positive normal phase and start tumor; Second stage---" hypertrophy ", is tumor cell paraplasm, exhausts physical ability, the whole body negative and positive fast-descending phase; Phase III---" development ", is tumor cell diffusion transfer, critically ill, and whole body negative and positive are significantly lowered the phase.Because the tumor first stage is often difficult for finding, the present invention is directed to the basic principle of second, third stage using " right supporting anticancer " as prescription.

2. multichannel righting promotes negative and positive.The one, tonification whole body, recovers brain, hypothalamic regulatory function and enhancing body hemopoietic, with warming and recuperating the kidney-YANG, improves general metabolism, improves vitality; The 2nd, strengthen digestive function, promote the absorption of gastrointestinal peristalsis and nutrient substance, recover energetically the transportation capabilities of spleen; The 3rd, enhancing human body immunity function, performance cellular immunization and humoral immune function are prevented cancerous protuberance cell; The 4th, application powerful antioxidant, protection human cell membrane is avoided cancer poison and is attacked.Common righting, recovers whole body negative and positive, improves the anti-cancer ability of body.

3. the anticancer not impairment of YIN of multichannel sun.The one, directly cancerous protuberance cell is killed in resistance; The 2nd, prevention cancerous protuberance neovascularity produces, cancerous protuberance develops and the transfer of cancerous protuberance; The 3rd, catharsis and toxin expelling, promotes poisonous substance to discharge; The 4th, need not be greatly bitter Great Cold, Chinese medicine and Pharmacopoeia of the People's Republic of China mark were released poisonous Chinese medicine, guaranteed anticancer just wound, did not for cancerly hurt sb.'s feelings.

4. the present invention can, separately for oncotherapy, also can coordinate operation, chemotherapy and radiation, the swollen curative effect that improves of Synergistic anti-cancer.

The specific embodiment

The present invention is Chinese medicine preparation for the treatment of tumor and preparation method thereof, now in conjunction with specific embodiments the present invention is further described.Concrete embodiment is as follows:

Embodiment mono-

A kind of Chinese medicine preparation for the treatment of tumor, this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 720 parts, 1 part of Radix Ginseng, 1 part of Radix Codonopsis, 1 part of Ganoderma, 1 part of Coriolous Dersicolor (Fr.) Quel, 1 part of Herba Epimedii, 1 part of Rhizoma Polygoni Cuspidati, 0.01 part, astaxanthin powder, 1 part of Radix Angelicae Sinensis, 1 part, Colla Corii Asini, 1～90 part of Carapax Trionycis (processed with vinegar), 1 part of Radix Sanguisorbae, 1 part, Rhizoma Curcumae Longae, 1 part of Herba Artemisiae Annuae, 1 part of Herba Scutellariae Barbatae, 1 part of Herba Agrimoniae, 1 part, Herba Silybi mariani extract powder, 1 part of Concha Ostreae powder, 1 part, Radish seed powder, 1 part of Pheretima powder, 1～90 part of Fructus Amomi, 1 part of Cortex Cinnamomi and water; Adjuvant comprises that following raw materials according is formulated according to parts by weight: 1 part of 1 part of oligofructose and white sugar.This preparation method comprises the steps:

Step 4: the first silk bag in step 2 is put into step 3 and add the bucket of boiling medicine of water to soak after 6h, decoct 1h;

The first silk bag in described step 2, the 3rd silk bag in the second silk bag and step 7 in step 5 is 150 order silk bags.The every bag of capacity arranging in bagging system in described step 10 is 100ml.Finished product warehouse-in in described step 10 is also preserved under the environment of 5 ℃.

Embodiment bis-

A kind of Chinese medicine preparation for the treatment of tumor, this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 30.5 parts of Radix Ginsengs, 90.5 parts of Radix Codonopsis, 60.5 parts of Ganodermas, 60.5 parts of Coriolous Dersicolor (Fr.) Quel, 60.5 parts of Herba Epimedii, 60.5 parts of Rhizoma Polygoni Cuspidati, 3.005 parts, astaxanthin powder, 60.5 parts of Radix Angelicae Sinensis, 45.5 parts, Colla Corii Asini, 45.5 parts of Carapax Trionycis (processed with vinegar), 45.5 parts of Radix Sanguisorbaes, 45.5 parts, Rhizoma Curcumae Longae, 45.5 parts of Herba Artemisiae Annuaes, 45.5 parts of Herba Scutellariae Barbataes, 45.5 parts of Herba Agrimoniaes, 15.5 parts, Herba Silybi mariani extract powder, 75.5 parts of Concha Ostreae powder, 75.5 parts, Radish seed powder, 45.5 parts of Pheretima powder, 45.5 parts of Fructus Amomis, 3960 parts, 30.5 parts of Cortex Cinnamomis and water, adjuvant comprises that following raw materials according is formulated according to parts by weight: 150.5 parts of 150.5 parts of oligofructoses and white sugars.This preparation method comprises the steps:

Step 1: get the raw materials ready: Radix Ginseng, Radix Codonopsis, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Herba Epimedii, Rhizoma Polygoni Cuspidati, astaxanthin powder, Radix Angelicae Sinensis, Colla Corii Asini, Carapax Trionycis (processed with vinegar), Radix Sanguisorbae, Rhizoma Curcumae Longae, Herba Artemisiae Annuae, Herba Scutellariae Barbatae, Herba Agrimoniae, Herba Silybi mariani extract powder, Concha Ostreae powder, Radish seed powder, Pheretima powder, Fructus Amomi, Cortex Cinnamomi, oligofructose and white sugar; Above-mentioned raw materials is got ready in the rear environment that is positioned over respectively 10 ℃ and is preserved;

Step 4: the first silk bag in step 2 is put into step 3 and add the bucket of boiling medicine of water to soak after 7h, decoct 1h;

The first silk bag in described step 2, the 3rd silk bag in the second silk bag and step 7 in step 5 is 150 order silk bags.The every bag of capacity arranging in bagging system in described step 10 is 200ml.Finished product warehouse-in in described step 10 is also preserved under the environment of 10 ℃.

Embodiment tri-

A kind of Chinese medicine preparation for the treatment of tumor, this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 60 parts of Radix Ginsengs, 180 parts of Radix Codonopsis, 120 parts of Ganodermas, 120 parts of Coriolous Dersicolor (Fr.) Quel, 120 parts of Herba Epimedii, 120 parts of Rhizoma Polygoni Cuspidati, 6 parts, astaxanthin powder, 120 parts of Radix Angelicae Sinensis, 90 parts, Colla Corii Asini, 90 parts of Carapax Trionycis (processed with vinegar), 90 parts of Radix Sanguisorbaes, 90 parts, Rhizoma Curcumae Longae, 90 parts of Herba Artemisiae Annuaes, 90 parts of Herba Scutellariae Barbataes, 90 parts of Herba Agrimoniaes, 30 parts, Herba Silybi mariani extract powder, 150 parts of Concha Ostreae powder, 150 parts, Radish seed powder, 90 parts of Pheretima powder, 90 parts of Fructus Amomis, 7200 parts, 60 parts of Cortex Cinnamomis and water, adjuvant comprises that following raw materials according is formulated according to parts by weight: 300 parts of 300 parts of oligofructoses and white sugars.This preparation method comprises the steps:

Step 1: get the raw materials ready: Radix Ginseng, Radix Codonopsis, Ganoderma, Coriolous Dersicolor (Fr.) Quel, Herba Epimedii, Rhizoma Polygoni Cuspidati, astaxanthin powder, Radix Angelicae Sinensis, Colla Corii Asini, Carapax Trionycis (processed with vinegar), Radix Sanguisorbae, Rhizoma Curcumae Longae, Herba Artemisiae Annuae, Herba Scutellariae Barbatae, Herba Agrimoniae, Herba Silybi mariani extract powder, Concha Ostreae powder, Radish seed powder, Pheretima powder, Fructus Amomi, Cortex Cinnamomi, oligofructose and white sugar; Above-mentioned raw materials is got ready in the rear environment that is positioned over respectively 15 ℃ and is preserved;

Step 4: the first silk bag in step 2 is put into step 3 and add the bucket of boiling medicine of water to soak after 8h, decoct 1h;

The first silk bag in described step 2, the 3rd silk bag in the second silk bag and step 7 in step 5 is 150 order silk bags.The every bag of capacity arranging in bagging system in described step 10 is 300ml.Finished product warehouse-in in described step 10 is also preserved under the environment of 15 ℃.

Embodiment tetra-

A kind of Chinese medicine preparation for the treatment of tumor, this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 3400 parts, 20 parts of Radix Ginsengs, 50 parts of Radix Codonopsis, 30 parts of Ganodermas, 20 parts of Coriolous Dersicolor (Fr.) Quel, 20 parts of Herba Epimedii, 20 parts of Rhizoma Polygoni Cuspidati, 0.5 part, astaxanthin powder, 15 parts of Radix Angelicae Sinensis, 20 parts, Colla Corii Asini, 20 parts of Carapax Trionycis (processed with vinegar), 15 parts of Radix Sanguisorbaes, 15 parts, Rhizoma Curcumae Longae, 9 parts of Herba Artemisiae Annuaes, 20 parts of Herba Scutellariae Barbataes, 9 parts of Herba Agrimoniaes, 15 parts, Herba Silybi mariani extract powder, 20 parts of Concha Ostreae powder, 20 parts, Radish seed powder, 15 parts of Pheretima powder, 12 parts of Fructus Amomis, 15 parts of Cortex Cinnamomis and water; Adjuvant comprises that following raw materials according is formulated according to parts by weight: 100 parts of 200 parts of oligofructoses and white sugars; This preparation method comprises the steps:

Embodiment five

A kind of Chinese medicine preparation for the treatment of tumor, this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 2300 parts, 18 parts of Radix Ginsengs, 30 parts of Radix Codonopsis, 20 parts of Ganodermas, 10 parts of Coriolous Dersicolor (Fr.) Quel, 15 parts of Herba Epimedii, 15 parts of Rhizoma Polygoni Cuspidati, 0.4 part, astaxanthin powder, 12 parts of Radix Angelicae Sinensis, 12 parts, Colla Corii Asini, 12 parts of Carapax Trionycis (processed with vinegar), 12 parts of Radix Sanguisorbaes, 12 parts, Rhizoma Curcumae Longae, 9 parts of Herba Artemisiae Annuaes, 15 parts of Herba Scutellariae Barbataes, 9 parts of Herba Agrimoniaes, 3 parts, Herba Silybi mariani extract powder, 15 parts of Concha Ostreae powder, 15 parts, Radish seed powder, 12 parts of Pheretima powder, 9 parts of Fructus Amomis, 9 parts of Cortex Cinnamomis and water; Adjuvant comprises that following raw materials according is formulated according to parts by weight: 400 parts of 200 parts of oligofructoses and white sugars; This preparation method comprises the steps:

Step 4: the first silk bag in step 2 is put into step 3 and add the bucket of boiling medicine of water to soak after 7.6h, decoct 1h;

Embodiment six

A kind of Chinese medicine preparation for the treatment of tumor, this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 55 parts of Radix Ginsengs, 136 parts of Radix Codonopsis, 117 parts of Ganodermas, 108 parts of Coriolous Dersicolor (Fr.) Quel, 112 parts of Herba Epimedii, 112 parts of Rhizoma Polygoni Cuspidati, 0.06 part, astaxanthin powder, 98 parts of Radix Angelicae Sinensis, 82.5 parts, Colla Corii Asini, 80 parts of Carapax Trionycis (processed with vinegar), 46 parts of Radix Sanguisorbaes, 87.7 parts, Rhizoma Curcumae Longae, 9 parts of Herba Artemisiae Annuaes, 50 parts of Herba Scutellariae Barbataes, 40 parts of Herba Agrimoniaes, 21.5 parts, Herba Silybi mariani extract powder, 136 parts of Concha Ostreae powder, 129 parts, Radish seed powder, 90 parts of Pheretima powder, 80 parts of Fructus Amomis, 3600 parts, 40 parts of Cortex Cinnamomis and water, adjuvant comprises that following raw materials according is formulated according to parts by weight: 150 parts of 200 parts of oligofructoses and white sugars, this preparation method comprises the steps:

Above-described embodiment is only for example is clearly described, and the not restriction to embodiment.For the common technique personnel in affiliated field, can also make other changes in different forms on the basis of the above description.It is a kind of Chinese medicine preparation for the treatment of cancer of the present invention; the proportioning of its raw material is not limited to above-described embodiment; the ratio range that can formulate according to claim 1; allocate arbitrarily, the apparent variation of being amplified out thus or variation are still among the protection domain in the invention claim.

The Chinese medicine extract relating in the present invention and Chinese crude drug; the Chinese crude drug that it is corresponding and extract; the corresponding Radix Codonopsis extract of Radix Ginseng extract, Radix Codonopsis as corresponding in Radix Ginseng; the Herba Silybi mariani Chinese crude drug that Herba Silybi mariani extract is corresponding, astaxanthin powder, corresponding astaxanthin, Pheretima and the Pheretima extract etc. of Pheretima powder all belong to the protection category of patent of the present invention.

A kind of Chinese medicine preparation for the treatment of cancer of the present invention, is not limited to above-mentioned dosage form or packing, can be processed as required other dosage form and packing.

Case 1: remaining so-and-so, female, 72 years old, peasant, made a definite diagnosis advanced esophageal cancer for 2007, transfer cannot be performed the operation, and adopts Biotherapeutics and therapeutic alliance of the present invention, keeps pleasant, result patient winter in 2011 is because of the death of flu pulmonary infection, " existence of band tumor " 5 years.

Case 2: what so-and-so, man, 61 years old, poor appetite 10 months, gastric cancer middle and advanced stage is made a definite diagnosis in CT, gastroscopy, has Coeliac lymphadenectomy, and operation adds the present invention and adheres to treatment so far, and invalid diet is normal, fecal occult blood is turned out cloudy, healthy, participates in veteran cadre's recreation, and self-induction is without obviously weak.

Case 3: Lee so-and-so, female, 65 years old, poor appetite 3 months, be in hospital CT, gastroscopy of acute hematemesis makes a definite diagnosis fundic gland cancer late period, and lymphonodi coeliaci extensively shifts, and does stomach large portion excision and lymphonodi coeliaci removing art 301, within postoperative 2 weeks, be still unable to leave the bed, abdominal distention poor appetite can only be drunk 30ml water or milk at every turn, takes decoct of the present invention 3 days, 200ml can be drunk at every turn, can drink every day 7 times, after 5 days, leave the bed and walk about, adhere to subsequently with the present invention, do not carry out chemotherapy, so far 3 years, take weekly the present invention once, patient body weight recovers, physical and mental health, health check-up is without extremely.

Case 4: 43 years old, Shen, cervical cancer mid-term is found in 2008 health check-ups, immediate surgery treatment, treats 3 years in conjunction with the present invention, adheres to so far taking medicine weekly once, healthy, normally working.

Case 5: Zhao so-and-so, man, 55 years old, healthy, 2008 run time fall down suddenly, examination in hospital is diagnosed as later period of hepatocarcinoma, cannot perform the operation, waiting for death, take the present invention maintain treatment a year and a half, multiple organs failure death.

Claims

1. treat the Chinese medicine preparation of tumor for one kind, it is characterized in that: this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 1～60 part of Radix Ginseng, 1～180 part of Radix Codonopsis, 1～120 part of Ganoderma, 1～120 part of Coriolous Dersicolor (Fr.) Quel, 1～120 part of Herba Epimedii, 1～120 part of Rhizoma Polygoni Cuspidati, 0.01～6 part, astaxanthin powder, 1～120 part of Radix Angelicae Sinensis, 1～90 part, Colla Corii Asini, 1～90 part of Carapax Trionycis (processed with vinegar), 1～90 part of Radix Sanguisorbae, 1～90 part, Rhizoma Curcumae Longae, 1～90 part of Herba Artemisiae Annuae, 1～90 part of Herba Scutellariae Barbatae, 1～90 part of Herba Agrimoniae, 1～30 part, Herba Silybi mariani extract powder, 1～150 part of Concha Ostreae powder, 1～150 part, Radish seed powder, 1～90 part of Pheretima powder, 1～90 part of Fructus Amomi, 720～7200 parts, 1～60 part of Cortex Cinnamomi and water, adjuvant comprises that following raw materials according is formulated according to parts by weight: 1～300 part of 1～300 part of oligofructose and white sugar.

2. the preparation method of the Chinese medicine preparation for the treatment of tumor according to claim 1, is characterized in that: this preparation method comprises the steps:

3. the preparation method of the Chinese medicine preparation for the treatment of tumor according to claim 2, is characterized in that: the first silk bag in described step 2, the 3rd silk bag in the second silk bag and step 7 in step 5 is 150 order silk bags.

4. the preparation method of the Chinese medicine preparation for the treatment of tumor according to claim 2, is characterized in that: the every bag of capacity arranging in bagging system in described step 10 is 100～300ml.

5. the preparation method of the Chinese medicine preparation for the treatment of tumor according to claim 2, is characterized in that: the finished product warehouse-in in described step 10 is also preserved under the environment of 5～15 ℃.

6. the Chinese medicine preparation for the treatment of tumor according to claim 1, it is characterized in that: this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 20 parts of Radix Ginsengs, 50 parts of Radix Codonopsis, 30 parts of Ganodermas, 20 parts of Coriolous Dersicolor (Fr.) Quel, 20 parts of Herba Epimedii, 20 parts of Rhizoma Polygoni Cuspidati, 0.5 part, astaxanthin powder, 15 parts of Radix Angelicae Sinensis, 20 parts, Colla Corii Asini, 20 parts of Carapax Trionycis (processed with vinegar), 15 parts of Radix Sanguisorbaes, 15 parts, Rhizoma Curcumae Longae, 9 parts of Herba Artemisiae Annuaes, 20 parts of Herba Scutellariae Barbataes, 9 parts of Herba Agrimoniaes, 15 parts, Herba Silybi mariani extract powder, 20 parts of Concha Ostreae powder, 20 parts, Radish seed powder, 15 parts of Pheretima powder, 12 parts of Fructus Amomis, 3400 parts, 15 parts of Cortex Cinnamomis and water, adjuvant comprises that following raw materials according is formulated according to parts by weight: 100 parts of 200 parts of oligofructoses and white sugars, this preparation method comprises the steps:

7. the Chinese medicine preparation for the treatment of tumor according to claim 1, it is characterized in that: this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 18 parts of Radix Ginsengs, 30 parts of Radix Codonopsis, 20 parts of Ganodermas, 10 parts of Coriolous Dersicolor (Fr.) Quel, 15 parts of Herba Epimedii, 15 parts of Rhizoma Polygoni Cuspidati, 0.4 part, astaxanthin powder, 12 parts of Radix Angelicae Sinensis, 12 parts, Colla Corii Asini, 12 parts of Carapax Trionycis (processed with vinegar), 12 parts of Radix Sanguisorbaes, 12 parts, Rhizoma Curcumae Longae, 9 parts of Herba Artemisiae Annuaes, 15 parts of Herba Scutellariae Barbataes, 9 parts of Herba Agrimoniaes, 3 parts, Herba Silybi mariani extract powder, 15 parts of Concha Ostreae powder, 15 parts, Radish seed powder, 12 parts of Pheretima powder, 9 parts of Fructus Amomis, 2300 parts, 9 parts of Cortex Cinnamomis and water, adjuvant comprises that following raw materials according is formulated according to parts by weight: 400 parts of 200 parts of oligofructoses and white sugars, this preparation method comprises the steps:

8. the Chinese medicine preparation for the treatment of tumor according to claim 1, it is characterized in that: this Chinese medicine preparation comprises major ingredient and adjuvant, wherein, major ingredient comprises that following raw materials according is formulated according to parts by weight: 55 parts of Radix Ginsengs, 136 parts of Radix Codonopsis, 117 parts of Ganodermas, 108 parts of Coriolous Dersicolor (Fr.) Quel, 112 parts of Herba Epimedii, 112 parts of Rhizoma Polygoni Cuspidati, 0.06 part, astaxanthin powder, 98 parts of Radix Angelicae Sinensis, 82.5 parts, Colla Corii Asini, 80 parts of Carapax Trionycis (processed with vinegar), 46 parts of Radix Sanguisorbaes, 87.7 parts, Rhizoma Curcumae Longae, 9 parts of Herba Artemisiae Annuaes, 50 parts of Herba Scutellariae Barbataes, 40 parts of Herba Agrimoniaes, 21.5 parts, Herba Silybi mariani extract powder, 136 parts of Concha Ostreae powder, 129 parts, Radish seed powder, 90 parts of Pheretima powder, 80 parts of Fructus Amomis, 3600 parts, 40 parts of Cortex Cinnamomis and water, adjuvant comprises that following raw materials according is formulated according to parts by weight: 150 parts of 200 parts of oligofructoses and white sugars, this preparation method comprises the steps: