CN102363023A - Chinese medicinal composition for treating leukemia - Google Patents
Chinese medicinal composition for treating leukemia Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal composition for treating leukemia. The Chinese medicinal composition is prepared from the following Chinese medicines: rubia cordifolia, sophora flavescens, almond, dahurian patrinia herb, natural indigo, turtle shell, zedoary, angelica sinensis, astragalus, codonopsis pilosula, bitter orange, manyflower solomonseal rhizome, arillus longan, glossy privet fruit, epimedium herb, dried rehmannia glutinosa, fructus psoraleae, caulis spatholobi, Japanese knotweed and liquorice. The Chinese medicinal composition for treating leukemia is prepared by the conventional decoction preparation method, all medicines are combined, and restrain and support each other, so kidney yin is nourished, healthy energy is supported, foul secretion is eliminated, pathogenic toxin is removed, the immunologic function is improved obviously, cancer cells are induced to be transformed into normal cells, and disease progress can be effectively controlled or relieved and the survival quality of a patient is improved while a human body is not damaged.
Description
Technical field
The present invention relates to the leukemic medicine of a kind of treatment, the leukemic Chinese medicine pharmaceutical composition of especially a kind of treatment.
Background technology
Leukemia is the malignant clone property disease of human body hemopoietic system, and in the past, leukemia is considered to incurable disease always, is once becoming dead synonym.Its pathological characters is to be characteristic so that the unrestricted hypertrophy of a large amount of korocytes to be arranged in bone marrow and other hemopoietic tissue, and extensively soaks into whole body normal structure and internal organs, causes its structure and function to be damaged.Clinical have in various degree anemia, hemorrhage, infectious fever and liver, spleen, lymphadenectasis, bone joint pain etc.Owing to leukemia natural disposition is obstinate, the cause of disease is complicated, causes the immunologic function major defect, and the harm patient body is healthy, even because of infection death.At present, the treatment leukemia has following several types: chemotherapy, radiotherapy, target therapy, bone marrow transplantation, treatment by Chinese herbs etc.In recent years, along with the progress of molecular biology, biogenetics, more deep to leukemic etiology and pathology understanding, new therapy, the discovery of novel drugs and the use of Chinese medicine are taken on a new look leukemic prognosis greatly simultaneously." leukemia is an incurable disease " becomes history.Regular, systematically treatment makes the long-term DFS of most of leukaemics, even recovery from illness.But, make the patient toxic action and systemic adverse reactions occur because chemotherapeutics normal " right and wrong are unclear ", " failing to differentiate between the enemy and ourselves " in killing tumor cell, been have also have been killed and wounded the human normal cell; Radiotherapy causes radiation reaction and damages such as alopecia, sweat gland afunction, atrophoderma, dry keratinization to human body.The major defect of bone marrow transplantation is exactly that the bone marrow type that is applicable to transplanting supplies source electrode few, because will find HLA (HLA) to join very difficulty of the identical bone marrow supplier of type.In general, in earlier stage+transplant in the cabin+after transplanting, need 600,000 yuan of left and right sides expenses altogether, generally the patient is difficult to bear.Chinese medicine is little with its side effect, and the treatment cost is low to be accepted by the leukaemic.The leukemic Chinese medicine of a lot of treatments has been declared patent, and what have has obtained exploitation.But most of traditional Chinese medicine composition for treating mechanism are not clear, control table and do not effect a permanent cure, and curative effect is very little.
Summary of the invention
The present invention is directed to deficiencies such as the side effect of the existing leukemia of treatment at present is big, unsatisfactory curative effect, a kind of determined curative effect is provided, has no side effect, is difficult for recurrence, can fundamentally treats leukemic Chinese medicine pharmaceutical composition.
The objective of the invention is to realize through following technical scheme: the leukemic Chinese medicine pharmaceutical composition of a kind of treatment, process by the raw material of following Chinese medicinal components and weight portion meter: Radix Rubiae 6-9, Radix Sophorae Flavescentis 3-9, Semen Armeniacae Amarum 4.5-9, Herba Patriniae 9-15, Indigo Naturalis 1.5-3, Carapax Trionycis 9-30, Rhizoma Curcumae 4.5-9, Radix Trichosanthis 9-15, Radix Angelicae Sinensis 6-15, Radix Astragali 9-15, Radix Codonopsis 9-15, Radix Ginseng 2-9, Fructus Aurantii 3-9, Rhizoma Polygonati 9-15, Ganoderma lucidum seu Japonicum 1.5-12, Arillus Longan 6-15, Fructus Ligustri Lucidi 9-15, Herba Epimedii 6-15, Semen Cuscutae 9-15, Radix Rehmanniae 9-30, Fructus Psoraleae 4.5-15, Caulis Spatholobi 9-15, Rhizoma Polygoni Cuspidati 9-30 and Radix Glycyrrhizae 1.5-15.
Said raw material components is preferably following parts by weight of component: Radix Rubiae 9, Radix Sophorae Flavescentis 9, Semen Armeniacae Amarum 6, Herba Patriniae 15, Indigo Naturalis 3, Carapax Trionycis 9, Rhizoma Curcumae 9, Radix Trichosanthis 12, Radix Angelicae Sinensis 12, the Radix Astragali 15, Radix Codonopsis 12, Radix Ginseng 9, Fructus Aurantii 9, Rhizoma Polygonati 15, Ganoderma lucidum seu Japonicum 6, Arillus Longan 12, Fructus Ligustri Lucidi 15, Herba Epimedii 9, Semen Cuscutae 15, Radix Rehmanniae 20, Fructus Psoraleae 12, Caulis Spatholobi 12, Rhizoma Polygoni Cuspidati 9 and Radix Glycyrrhizae 12.
The leukemic Chinese medicine composition of treatment of the present invention prepares in order to the below method: 1, with mixing after each tcm components metering, put into the medicine pot, add 8-10 doubly to the drinking water of medical material weight, soaked above-mentioned medical material 40-50 minute; 2, be heated to boiling with big fire after, use moderate heat instead and continue to decoct, when treating the surplus 200ml of medicinal liquid, medicinal liquid is leached, for use; The medicinal residues that 3, will leach behind the medicinal liquid add 6-8 drinking water doubly again, be heated to boiling with big fire after, use moderate heat instead and continue to decoct, when treating the surplus 200ml of medicinal liquid, medicinal liquid is leached, for use; 4, twice medicinal liquid for use mixed to pour in the medicine pot continue to decoct with little fire, when treating the surplus 200ml of pot herb liquid, taking-up gets final product.
Usage and consumption: potion on the one, each 100ml of morning and evening, eliminating cold for resuscitation water send down.
The present invention is the leukemic Chinese medicine pharmaceutical composition of a kind of treatment, and its dosage form is a said decoction in the Chinese materia medica, also can be prepared into powder, pill, unguentum, granule, medicated wine or oral liquid.
Leukemia belongs to Chinese medicine " asthenia ", " hot labor ", " acute pulmonary tuberculosis ", " epidemic febrile disease " categories such as " mass formed by blood stasis ".Cause a disease because of void, think because of the positive QI-insufficiency of body, the empty internal injury of body is subject to the evil invasion and attack of poison, going from the exterior into the interior, and positive exogenous pathogen is contained, and it is cloudy to injure battalion, involve in kidney, bone marrow damage, hemopoietic is not enough, and blood deficiency takes place.The course of disease is of a specified duration slightly, and QI and blood more loses, qi depression to blood stasis, and venation is blocked; Also can lie prostrate in the evil earlier poison, the positive exogenous pathogen in back is contained, and deficiency and excess is held concurrently mutually, the card of deficiency in origin and excess in superficiality.According to leukemia disease characteristics, start with from supplementing QI and nourishing YIN, benefiting qi and nourishing blood in the side, dual-purpose heat-clearing and toxic substances removing, the damp eliminating of invigorating blood circulation, reach immunity enhancing, bacterium and control, evil poison two is clear cures leukemic purpose.
Ganoderma lucidum seu Japonicum, Radix Ginseng, Radix Codonopsis, the Radix Astragali, Rhizoma Polygonati are cultivated healthy energy, supplementing QI and nourishing YIN in the component; Radix Angelicae Sinensis, Arillus Longan, Radix Rubiae, Caulis Spatholobi nutrition blood, blood-enriching tranquillizing; Fructus Ligustri Lucidi, Semen Cuscutae, Carapax Trionycis, Fructus Psoraleae, Herba Epimedii the kidney invigorating and essence nourishing, YIN nourishing are strong; Radix Trichosanthis, Radix Rehmanniae, Indigo Naturalis, Herba Patriniae, Rhizoma Polygoni Cuspidati, Radix Sophorae Flavescentis heat-clearing and toxic substances removing, promote the production of body fluid and moisturize; Fructus Aurantii, Semen Armeniacae Amarum, Radix Glycyrrhizae, Rhizoma Curcumae removing food stagnancy promoting the circulation of QI, dissipating phlegm and resolving masses; All medicines share, and restrain mutually, support mutually again, and drug effect is collaborative; Kidney yin must be grown, just be so incensed that to hold up, foul must the change, evil malicious clearly; Immunologic function improves rapidly, and inducing tumor cell transforms to normal cell, when not damaging patient body, and effectively control or mitigate the disease development; Improve patient's life quality, treating both the principal and secondary aspects of a disease of the present invention, stable curative effect is reliable.
The specific embodiment
Embodiment 1:
The present invention takes by weighing by following Chinese medicinal components and weight portion: Radix Rubiae 6-9; Radix Sophorae Flavescentis 3-9; Semen Armeniacae Amarum 4.5-9; Herba Patriniae 9-15; Indigo Naturalis 1.5-3; Carapax Trionycis 9-30; Rhizoma Curcumae 4.5-9; Radix Trichosanthis 9-15; Radix Angelicae Sinensis 6-15; Radix Astragali 9-15; Radix Codonopsis 9-15; Radix Ginseng 2-9; Fructus Aurantii 3-9; Rhizoma Polygonati 9-15; Ganoderma lucidum seu Japonicum 5-12; Arillus Longan 6-15; Fructus Ligustri Lucidi 9-15; Herba Epimedii 6-15; Semen Cuscutae 9-15; Radix Rehmanniae 9-30; Fructus Psoraleae 4.5-15; Caulis Spatholobi 9-15; Rhizoma Polygoni Cuspidati 9-30 and Radix Glycyrrhizae 1.5-15.
Its preparation method is:
1, with mixing after each tcm components metering, puts into the medicine pot, add 8-10, soaked above-mentioned medical material 40-50 minute doubly to the drinking water of medical material weight;
2, be heated to boiling with big fire after, use moderate heat instead and continue to decoct, when treating the surplus 200ml of medicinal liquid, medicinal liquid is leached, for use;
The medicinal residues that 3, will leach behind the medicinal liquid add 6-8 drinking water doubly again, be heated to boiling with big fire after, use moderate heat instead and continue to decoct, when treating the surplus 200ml of medicinal liquid, medicinal liquid is leached, for use;
4, twice medicinal liquid for use mixed to pour in the medicine pot continue to decoct with little fire, when treating the surplus 200ml of pot herb liquid, taking-up gets final product.Potion on the one, each 100ml of morning and evening, eliminating cold for resuscitation water send down.
Embodiment 2:
Take by weighing by following Chinese medicinal components and weight portion: Radix Rubiae 9, Radix Sophorae Flavescentis 9, Semen Armeniacae Amarum 6, Herba Patriniae 15, Indigo Naturalis 3, Carapax Trionycis 9, Rhizoma Curcumae 9, Radix Trichosanthis 12, Radix Angelicae Sinensis 12, the Radix Astragali 15, Radix Codonopsis 12, Radix Ginseng 9, Fructus Aurantii 9, Rhizoma Polygonati 15, Ganoderma lucidum seu Japonicum 6, Arillus Longan 6, Fructus Ligustri Lucidi 15, Herba Epimedii 9, Semen Cuscutae 15, Radix Rehmanniae 20, Fructus Psoraleae 12, Caulis Spatholobi 12, Rhizoma Polygoni Cuspidati 9 and Radix Glycyrrhizae 12.
Method for preparing is:
1, with mixing after each tcm components metering, puts into the medicine pot, add 8-10, soaked above-mentioned medical material 40-50 minute doubly to the drinking water of medical material weight;
2, be heated to boiling with big fire after, use moderate heat instead and continue to decoct, when treating the surplus 200ml of medicinal liquid, medicinal liquid is leached, for use;
The medicinal residues that 3, will leach behind the medicinal liquid add 6-8 drinking water doubly again, be heated to boiling with big fire after, use moderate heat instead and continue to decoct, when treating the surplus 200ml of medicinal liquid, medicinal liquid is leached, for use;
4, twice medicinal liquid for use mixed to pour in the medicine pot continue to decoct with little fire, when treating the surplus 200ml of pot herb liquid, taking-up gets final product.One order potion, each 100ml of morning and evening, eliminating cold for resuscitation water send down.
Case is given an example:
Case 1: Japanese plum spring man 52 years old, live traction therapy town, Jiaohe City, Jilin Province, on May 15th, 2010 because of the anorexia of becoming thin, repeatedly low grade fever in the Jilin Center Hospital hospitalization, assay is: leukocyte count is 62.6 * 10
9/ L, erythrocyte are 3.7 * 10
12/ L, platelet is 76.3 * 10
9/ L, granulocyte is 86.5%, is diagnosed as chronic myelocytic leukemia.Hospitalize 1 month, the state of an illness did not take a turn for the better, and hepatosplenomegaly occurs, and obvious tenderness is arranged, edema of lower limbs, purpura, nasal cavity, oral hemorrhage.On July 6th, 2010, look for me to seek medical advice upon somebody's introduction, through looking into hesitant pulse, purplish tongue, thin fur.Taking the present invention and treat leukemic Chinese medicine composition decoction, whenever is potion, divides twice decoction being taken warmly sooner or later, the existing positive effect of the state of an illness after 3 days.After taking 32 days, assay is: leukocyte count is 6.5 * 10
9/ L, erythrocyte are 5 * 10
12/ L, platelet is 157 * 10
9/ L, granulocyte are 53.8%, have reverted to normally, advise its 2 weeks back drug withdrawals that continue to take medicine, and follow up a case by regular visits to for several times the back of recovering, and all are normal so far.
27 years old laid-off worker of case 2: Zhang Huairen man, be diagnosed as acute nonlymphocytic leukemia by Jilin second hospital in JIUYUE, 2009.Here diagnosis and treatment afterwards, disease is seen: low grade fever, have a dizzy spell, the soreness of waist is weak, dysphoria with feverish sensation in the chest palms and soles, bleeding from the gum, red tongue, tongue stripping, thready and rapid pulse.Take the present invention and treat leukemic Chinese medicine composition decoction, every day, potion divided twice decoction being taken warmly sooner or later, and the state of an illness both took a favorable turn after 5 days.Surplus through controlling February, alleviation is gone home, drug withdrawal after continuing again to take medicine a year.It is normal to work now, live, and on July 18th, 2011 was checked the result to the Second Academy: Hb:155g/L; WBC:5.3 * 10
9/ L; BPC:119 * 10
9/ L, bone is worn inspection: bone marrow smear is normal.
Case 3: 51 years old Jilin Chuanying District people of yellow refined fragrant woman, occur having a dizzy spell, general weakness, breastbone tenderness, feel sick in August, 2009, seriousness purpura, pale complexion, assay is that leukocyte count is 41 * 10
9/ L, erythrocyte are 1.6 * 10
12/ L, platelet is 53 * 10
9/ L, myeloblast are 46.5%, and second hospital is diagnosed as hypoplastic acute leukemia through the Jilin.Because of badly off, no money is in hospital.Introduce come here treatment through the people in April, 2010.Look into: pulse condition flood number, the red silk ribbon of tongue nature, dry and yellowish fur, parched lips, skin has ecchymosis.Take the present invention and treat leukemic Chinese medicine composition decoction, every day, potion divided twice decoction being taken warmly sooner or later, the existing positive effect of the state of an illness after 6 days.After taking 30 days, it is normal that own sensation has been recovered.Second Academy's inspection to the city: the result is: leukocyte count is 8.5 * 10
9/ L, erythrocyte are 4.2 * 10
12/ L, platelet is 160 * 10
9/ L, myeloblast is 2.3%, advises its 3 weeks back drug withdrawal that continues to take medicine, and follow up a case by regular visits to for several times the back of recovering, and recurrence can not done work in power.
Case 4: Jiang Yu man 39 years old Jilin people from Shulan general weakness, extremity edema, spontaneous perspiration occur, feels sick, headache, skin have purpura, pale complexion in June, 2010, and coming institute's assay is that leukocyte count is 46.3 * 10
9/ L, erythrocyte are 3.7 * 10
12/ L, platelet is 70.8 * 10
9/ L, mononuclear cell is 50.5%, the hospitals of traditional Chinese and western medicine are diagnosed as acute monocytic leukemia through the Jilin.After this institute treats 3 months, the commentaries on classics of not getting better yet, the state of an illness also increases the weight of to some extent, and in October, 2010, here was accepted with the leukemic Chinese medicine medicine composite for curing of treatment of the present invention.Look into: unable a little less than the pulse condition, there is indentation on pale tongue and limit, white and moist fur, parched lips.Take the present invention and treat leukemic Chinese medicine composition decoction, every day, potion divided twice decoction being taken warmly sooner or later, and the state of an illness both produced effect after 3 days.After taking 40 days, oneself is felt good.Through lab testing, the result is: leukocyte count is 8.0 * 10
9/ L, erythrocyte are 5.2 * 10
12/ L, platelet is 148 * 10
9/ L, mononuclear cell is 6.5%, advises its 3 weeks back drug withdrawal that continues to take medicine, and after recovering, follows up a case by regular visits to for several times, and is healthy so far.
16 years old Jilin Longtan District people of case 5: Ning Chunzhi woman; In March, 2010 is at an inboard place painless property lump that occurs of its frame, after exposing in the sun; Marennin disappears rapidly; And with symptoms such as unable, pale complexion, constipation, giddy, heating, oral mucosa irritation, the chemical industry hospital general check through Jilin, the result is: leukocyte count is 131 * 10
9/ L, erythrocyte are 1.9 * 10
12/ L, platelet is 56 * 10
9/ L, myeloblast is 90.5%, is diagnosed as chloroma leucocythemia.Introduce come here treatment through the people in June, 2010.Look into: pulse condition is carefully unable, pale tongue.Take the present invention and treat leukemic Chinese medicine composition decoction, every day, potion divided twice decoction being taken warmly sooner or later, and clinical Signs is clearly better after 5 days, appetite increases, conscious health had had strength than in the past.After continuing again to take 2 months, the own sensation of patient has recovered normal.Through lab testing: the result is: leukocyte count is 6.25 * 10
9/ L, erythrocyte are 4.6 * 10
12/ L, platelet is 129 * 10
9/ L, granulocyte is 59.3%, advises its 2 weeks back drug withdrawal that continues to take medicine, and follows up a case by regular visits to after recovering and fully recovers, so far not bounce-back.
Claims (2)
1. treat leukemic Chinese medicine pharmaceutical composition for one kind, it is characterized in that: it is to be processed by the raw material of following Chinese medicinal components and weight portion meter: Radix Rubiae 6-9, Radix Sophorae Flavescentis 3-9, Semen Armeniacae Amarum 4.5-9, Herba Patriniae 9-15, Indigo Naturalis 1.5-3, Carapax Trionycis 9-30, Rhizoma Curcumae 4.5-9, Radix Trichosanthis 9-15, Radix Angelicae Sinensis 6-15, Radix Astragali 9-15, Radix Codonopsis 9-15, Radix Ginseng 2-9, Fructus Aurantii 3-9, Rhizoma Polygonati 9-15, Ganoderma lucidum seu Japonicum 5-12, Arillus Longan 6-15, Fructus Ligustri Lucidi 9-15, Herba Epimedii 6-15, Semen Cuscutae 9-15, Radix Rehmanniae 9-30, Fructus Psoraleae 4.5-15, Caulis Spatholobi 9-15, Rhizoma Polygoni Cuspidati 9-30 and Radix Glycyrrhizae 1.5-15.
2. the leukemic Chinese medicine pharmaceutical composition of a kind of treatment according to claim 1 is characterized in that: it is to be processed by the raw material of following Chinese medicinal components and weight portion meter: Radix Rubiae 9, Radix Sophorae Flavescentis 9, Semen Armeniacae Amarum 6, Herba Patriniae 15, Indigo Naturalis 3, Carapax Trionycis 9, Rhizoma Curcumae 9, Radix Trichosanthis 12, Radix Angelicae Sinensis 12, the Radix Astragali 15, Radix Codonopsis 12, Radix Ginseng 9, Fructus Aurantii 9, Rhizoma Polygonati 15, Ganoderma lucidum seu Japonicum 6, Arillus Longan 12, Fructus Ligustri Lucidi 15, Herba Epimedii 9, Semen Cuscutae 15, Radix Rehmanniae 20, Fructus Psoraleae 12, Caulis Spatholobi 12, Rhizoma Polygoni Cuspidati 9 and Radix Glycyrrhizae 12.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055094A (en) * | 2012-12-26 | 2013-04-24 | 柳州市中医院 | Traditional Chinese medicine for treating leukemia and preparation method thereof |
| CN103053908A (en) * | 2013-01-22 | 2013-04-24 | 山西大学 | Functional food capable of rising white blood cells and preparation method thereof |
| CN103877499A (en) * | 2014-03-12 | 2014-06-25 | 张玉珍 | Chinese herbal preparation for treating tumors and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099631A (en) * | 1993-09-04 | 1995-03-08 | 王峰 | Medicine for curing variety of anemia and leukemia |
| CN1260983A (en) * | 1999-01-21 | 2000-07-26 | 仇殿明 | Process for preparing leukemia medicines |
| CN1390588A (en) * | 2002-08-06 | 2003-01-15 | 王凯 | Composite medicine for treating leukemia |
-
2011
- 2011-11-25 CN CN2011103791152A patent/CN102363023A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099631A (en) * | 1993-09-04 | 1995-03-08 | 王峰 | Medicine for curing variety of anemia and leukemia |
| CN1260983A (en) * | 1999-01-21 | 2000-07-26 | 仇殿明 | Process for preparing leukemia medicines |
| CN1390588A (en) * | 2002-08-06 | 2003-01-15 | 王凯 | Composite medicine for treating leukemia |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055094A (en) * | 2012-12-26 | 2013-04-24 | 柳州市中医院 | Traditional Chinese medicine for treating leukemia and preparation method thereof |
| CN103053908A (en) * | 2013-01-22 | 2013-04-24 | 山西大学 | Functional food capable of rising white blood cells and preparation method thereof |
| CN103053908B (en) * | 2013-01-22 | 2014-04-09 | 山西大学 | Functional food capable of rising white blood cells and preparation method thereof |
| CN103877499A (en) * | 2014-03-12 | 2014-06-25 | 张玉珍 | Chinese herbal preparation for treating tumors and preparation method thereof |
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Application publication date: 20120229 |