CN102512592A - Traditional Chinese medicine capsule for treating refractory idiopathic thrombocytopenic purpura and preparation method for same - Google Patents
Traditional Chinese medicine capsule for treating refractory idiopathic thrombocytopenic purpura and preparation method for same Download PDFInfo
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- CN102512592A CN102512592A CN2011104235182A CN201110423518A CN102512592A CN 102512592 A CN102512592 A CN 102512592A CN 2011104235182 A CN2011104235182 A CN 2011104235182A CN 201110423518 A CN201110423518 A CN 201110423518A CN 102512592 A CN102512592 A CN 102512592A
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Abstract
The invention relates to a medicine for treating hematopathy, particularly to a traditional Chinese medicine capsule for treating refractory idiopathic thrombocytopenic purpura and a preparation method for the same, wherein the traditional Chinese medicine capsule is composed of traditional Chinese medicine raw materials in the following parts by weight: 30-50 parts of cornu bubali powder, 2-4 parts of tripterygium wilfordii, 12-30 parts of indigo naturalis, 30-50 parts of scutellaria baicalensis, 30-50 parts of coptis chinensis, 30-50 parts of isatis root, 30-50 parts of callicarpa bodinieri, 30-50 parts of astragalus mongholicus, 20-45 parts of donkey-hide gelatin, 30-50 parts of angelica sinensis, 30-50 parts of caulis spatholobi, 30-50 parts of polygonum multiflorum, 30-50 parts of rhizoma polygonati, 30-45 parts of radix rehmanniae preparata, 30-50 parts of agrimonia pilosa, 30-50 parts of moutan bark and 30-50 parts of liquorice. The preparation method comprises the following steps of: crushing traditional Chinese medicine raw materials composed by weight; mixing the traditional Chinese medicine raw materials with the refined honey and then drying; and crushing into powder and then filling in capsules.
Description
Technical field
The present invention relates to the hemopathic medicine of a kind of treatment, particularly a kind of method for preparing of treating the Chinese medicinal capsule of idiopathic thrombocytopenic purpura.
Background technology
Idiopathic thrombocytopenic purpura is a kind of immune-mediated thrombocytopenia syndrome; With mucocutaneous, visceral hemorrhage and peripheral blood thrombocytopenia is characteristic; Bone marrow megakaryocyte quantity increases, normal or minimizing; Companion's dysmaturity, treatment that at present should disease is main with experience, does not still have generally acknowledged Therapeutic Principle.Though glucocorticoid is the choice drug of idiopathic thrombocytopenic purpura; But decrement or drug withdrawal are easy to recurrence; And the long-term treatment adverse reaction rate is high, and the effect of immunosuppressant toxic and side effects is big, can not be lasting and the treatment of intravenous applications gamma globulin is many.The Chinese medicine primary disease belongs to " mass formed by blood stasis ", " sending out speckle ", " asthenia " category.The overall side effect of western medical treatment is big, and relapse rate is high, and mortality rate is about about 1%.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicinal capsule of treating idiopathic thrombocytopenic purpura and preparation method thereof, it has heat-clearing and toxic substances removing, cooling blood for hemostasis, liver and kidney tonifying, invigorating the spleen and benefiting QI, effects such as blood circulation promoting and blood stasis dispelling.Effectively promote platelet counts.
The object of the invention can adopt following technical scheme to come real the sight: the Chinese medicinal capsule of described treatment idiopathic thrombocytopenic purpura, form by following parts by weight of Chinese traditional medicine raw material:
Cornu Bubali powder 30-50 part, Radix Tripterygii Wilfordii 2-4 part, Indigo Naturalis 12-30 part, Radix Scutellariae 30-50 part, Rhizoma Coptidis 30-50 part; Radix Isatidis 30-50 part, Folium Callicarpae Formosanae 30-50 part, Radix Astragali 30-50 part, Colla Corii Asini 20-45 part; Radix Angelicae Sinensis 30-50 part, Caulis Spatholobi 30-50 part, Radix Polygoni Multiflori 30-50 part, Rhizoma Polygonati 30-50 part; Radix Rehmanniae Preparata 30-45 part, Herba Agrimoniae 30-50 part, Cortex Moutan 30-50 part, Radix Glycyrrhizae 30-50 part.
The capsule preparation method thereof of said Chinese medicine: above-mentioned raw material of Chinese medicine is pulverized, mixed the back oven dry with the good Mel of refining then, be ground into Powdered incapsulating after the oven dry again.
Chinese medicine is learned to study and is shown in the important source material of the present invention, wherein:
Cornu Bubali powder: bitter in the mouth, cold in nature, have heat-clearing and toxic substances removing, the effect of cooling blood for hemostasis;
Radix Tripterygii Wilfordii: bitter in the mouth, cold in nature, have expelling wind and removing dampness, effects such as dispelling toxins and dredging collaterals;
Indigo Naturalis: bitter in the mouth, cold in nature, nontoxic, have the effect of heat clearing away, removing heat from blood, detoxifcation;
Radix Scutellariae: bitter in the mouth, cold in nature, have heat clearing and damp drying, the effect of hemostasis;
Rhizoma Coptidis: bitter in the mouth, cold in nature, have the effect of eliminating fire and detoxication;
Radix Isatidis: bitter in the mouth, cold in nature, the effect of heat-clearing and toxic substances removing, blood cooling and ecchymoses removing;
Folium Callicarpae Formosanae: bitter in the mouth, cold in nature, puckery, cool, have heat-clearing and toxic substances removing, the effect of cooling blood for hemostasis;
The Radix Astragali: nature and flavor are sweet, and tepor has the effect of qi-supplementing, blood-engendering;
Colla Corii Asini: nature and flavor are sweet, have enrich blood, the effect of removing heat from blood, lung moistening, YIN nourishing;
Radix Angelicae Sinensis: sweet in the mouth is hot, and tepor has the effect of tonifying blood and arresting bleeding;
Caulis Spatholobi: nature and flavor, sweet, hardship, tepor has tonifying blood and arresting bleeding, the effect of collateral dredging;
Radix Polygoni Multiflori: nature and flavor, sweet puckery, tepor has invigorating the liver and kidney, the effect of benefiting essence-blood;
Rhizoma Polygonati: sweet in the mouth, property is flat, has supplementing QI and nourishing YIN, the effect of mediation the five internal organs;
Radix Rehmanniae Preparata: nature and flavor are sweet, and tepor has the effect of the YIN nourishing of enriching blood;
Herba Agrimoniae: nature and flavor, bitter cool, have the effect of cooling blood for hemostasis;
Cortex Moutan: cold in nature, bitter in the mouth has the effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis;
Radix Glycyrrhizae: nature and flavor are sweet flat, have invigorating the spleen and replenishing QI, the effect of heat-clearing and toxic substances removing, mediation principal agent.
The present invention forms through long-term clinical practice research; Main pathogenesis according to idiopathic thrombocytopenic purpura is " heat, empty, the stasis of blood " three kinds, and the medicine of employing has clearing away heat and cooling blood hemostasis, boosting qi and nourishing yin; Blood circulation promoting and blood stasis dispelling; Liver and kidney tonifying, invigorating the spleen and benefiting QI promotes platelet, hemostatic purpose thereby reach.
Medicine of the present invention was used to treat idiopathic thrombocytopenic purpura 350 examples in 5 years, and total effective rate reaches about 95%, and the treatment criterion of therapeutical effect is according to " hematopathy diagnosis and the treatment standard " third edition one book of Zhang Zhinan chief editor.Most patients use onset in back two days, stopped bleeding.Shang Weijian has dead patient to take place.
The specific embodiment
Embodiment 1:Described Chinese medicinal capsule is made up of following raw material of Chinese medicine by weight: 30 parts of Cornu Bubali powders, 2 parts of Radix Tripterygii Wilfordiis, 16 parts of Indigo Naturaliss, 30 parts of Radix Scutellariaes, 30 parts of Rhizoma Coptidis; 35 parts of Radix Isatidis, 30 parts of Folium Callicarpae Formosanaes, 30 parts of the Radixs Astragali, 20 parts in Colla Corii Asini; 30 parts of Radix Angelicae Sinensis, 30 parts of Caulis Spatholobis, 30 parts of Radix Polygoni Multiflori, 30 parts of Rhizoma Polygonatis; 30 parts in Radix Rehmanniae Preparata, 30 parts of Herba Agrimoniaes, 30 parts of Cortex Moutans, 30 parts in Radix Glycyrrhizae.
Method for preparing: above-mentioned raw material of Chinese medicine is pulverized, mixed the back oven dry with the good Mel of refining then, be ground into Powdered incapsulating after the oven dry again.
Embodiment 2:Described Chinese medicinal capsule is made up of following raw material of Chinese medicine by weight: 40 parts of Cornu Bubali powders, 3 parts of Radix Tripterygii Wilfordiis, 20 parts of Indigo Naturaliss, 40 parts of Radix Scutellariaes, 40 parts of Rhizoma Coptidis; 40 parts of Radix Isatidis, 40 parts of Folium Callicarpae Formosanaes, 40 parts of the Radixs Astragali, 30 parts in Colla Corii Asini; 40 parts of Radix Angelicae Sinensis, 40 parts of Caulis Spatholobis, 40 parts of Radix Polygoni Multiflori, 40 parts of Rhizoma Polygonatis; 40 parts in Radix Rehmanniae Preparata, 40 parts of Herba Agrimoniaes, 40 parts of Cortex Moutans, 40 parts in Radix Glycyrrhizae.
Method for preparing: above-mentioned raw material of Chinese medicine is pulverized, mixed the back oven dry with the good Mel of refining then, be ground into Powdered incapsulating after the oven dry again.
Embodiment 3:Described Chinese medicinal capsule is made up of following raw material of Chinese medicine by weight: 50 parts of Cornu Bubali powders, 4 parts of Radix Tripterygii Wilfordiis, 30 parts of Indigo Naturaliss, 50 parts of Radix Scutellariaes, 50 parts of Rhizoma Coptidis; 50 parts of Radix Isatidis, 50 parts of Folium Callicarpae Formosanaes, 50 parts of the Radixs Astragali, 45 parts in Colla Corii Asini; 50 parts of Radix Angelicae Sinensis, 50 parts of Caulis Spatholobis, 50 parts of Radix Polygoni Multiflori, 50 parts of Rhizoma Polygonatis; 45 parts in Radix Rehmanniae Preparata, 50 parts of Herba Agrimoniaes, 50 parts of Cortex Moutans, 45 parts in Radix Glycyrrhizae.
Method for preparing: above-mentioned raw material of Chinese medicine is pulverized, mixed the back oven dry with the good Mel of refining then, be ground into Powdered incapsulating after the oven dry again.
Claims (5)
1. a Chinese medicinal capsule of treating idiopathic thrombocytopenic purpura is characterized in that being made up of following parts by weight of Chinese traditional medicine raw material: Cornu Bubali powder 30-50 part, Radix Tripterygii Wilfordii 2-4 part, Indigo Naturalis 12-30 part, Radix Scutellariae 30-50 part; Rhizoma Coptidis 30-50 part, Radix Isatidis 30-50 part, Folium Callicarpae Formosanae 30-50 part, Radix Astragali 30-50 part, Colla Corii Asini 20-45 part; Radix Angelicae Sinensis 30-50 part, Caulis Spatholobi 30-50 part, Radix Polygoni Multiflori 30-50 part, Rhizoma Polygonati 30-50 part; Radix Rehmanniae Preparata 30-45 part, Herba Agrimoniae 30-50 part, Cortex Moutan 30-50 part, Radix Glycyrrhizae 30-50 part.
2. the Chinese medicinal capsule of treatment idiopathic thrombocytopenic purpura according to claim 1 is characterized in that being made up of following parts by weight of Chinese traditional medicine raw material: 30 parts of Cornu Bubali powders, 2 parts of Radix Tripterygii Wilfordiis, 16 parts of Indigo Naturaliss, 30 parts of Radix Scutellariaes; 30 parts of Rhizoma Coptidis, 35 parts of Radix Isatidis, 30 parts of Folium Callicarpae Formosanaes, 30 parts of the Radixs Astragali, 20 parts in Colla Corii Asini; 30 parts of Radix Angelicae Sinensis, 30 parts of Caulis Spatholobis, 30 parts of Radix Polygoni Multiflori, 30 parts of Rhizoma Polygonatis; 30 parts in Radix Rehmanniae Preparata, 30 parts of Herba Agrimoniaes, 30 parts of Cortex Moutans, 30 parts in Radix Glycyrrhizae.
3. the Chinese medicinal capsule of treatment idiopathic thrombocytopenic purpura according to claim 1 is characterized in that being made up of following parts by weight of Chinese traditional medicine raw material: 40 parts of Cornu Bubali powders, 3 parts of Radix Tripterygii Wilfordiis, 20 parts of Indigo Naturaliss, 40 parts of Radix Scutellariaes; 40 parts of Rhizoma Coptidis, 40 parts of Radix Isatidis, 40 parts of Folium Callicarpae Formosanaes, 40 parts of the Radixs Astragali, 30 parts in Colla Corii Asini; 40 parts of Radix Angelicae Sinensis, 40 parts of Caulis Spatholobis, 40 parts of Radix Polygoni Multiflori, 40 parts of Rhizoma Polygonatis; 40 parts in Radix Rehmanniae Preparata, 40 parts of Herba Agrimoniaes, 40 parts of Cortex Moutans, 40 parts in Radix Glycyrrhizae.
4. treatment specificity platelet according to claim 1 reduces the Chinese medicinal capsule of purpura, it is characterized in that being made up of following parts by weight of Chinese traditional medicine raw material: 50 parts of Cornu Bubali powders, 4 parts of Radix Tripterygii Wilfordiis, 30 parts of Indigo Naturaliss, 50 parts of Radix Scutellariaes; 50 parts of Rhizoma Coptidis, 50 parts of Radix Isatidis, 50 parts of Folium Callicarpae Formosanaes, 50 parts of the Radixs Astragali, 45 parts in Colla Corii Asini; 50 parts of Radix Angelicae Sinensis, 50 parts of Caulis Spatholobis, 50 parts of Radix Polygoni Multiflori, 50 parts of Rhizoma Polygonatis; 45 parts in Radix Rehmanniae Preparata, 50 parts of Herba Agrimoniaes, 50 parts of Cortex Moutans, 45 parts in Radix Glycyrrhizae.
5. power such as profit require 1 or 2 or the method for preparing of the Chinese medicinal capsule of 3 or 4 said treatment idiopathic thrombocytopenic purpuras; It is characterized in that: will be according to the parts by weight of Chinese traditional medicine raw material pulverizing; Mix the back oven dry with the good Mel of refining then, be ground into Powdered incapsulating after the oven dry again.
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Cited By (5)
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| CN102772685A (en) * | 2012-07-16 | 2012-11-14 | 梁艳龙 | Traditional Chinese medicinal preparation for treating aplastic anemia |
| CN103316243A (en) * | 2013-06-26 | 2013-09-25 | 张秀兰 | Drug for treating thrombocytopenic purpura and preparation method thereof |
| CN103690692A (en) * | 2013-11-29 | 2014-04-02 | 周晨 | Traditional Chinese medicine formula for treating purpura |
| CN105055637A (en) * | 2015-08-28 | 2015-11-18 | 蒋玉群 | Traditional Chinese medicine composition for treating thrombocytopenic purpura |
| CN105663674A (en) * | 2016-01-27 | 2016-06-15 | 济南正骐生物科技有限公司 | Traditional Chinese medicine for treating thrombocytopenic purpura and preparation method of traditional Chinese medicine |
-
2011
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772685A (en) * | 2012-07-16 | 2012-11-14 | 梁艳龙 | Traditional Chinese medicinal preparation for treating aplastic anemia |
| CN102772685B (en) * | 2012-07-16 | 2014-07-02 | 梁艳龙 | Traditional Chinese medicinal preparation for treating aplastic anemia |
| CN103316243A (en) * | 2013-06-26 | 2013-09-25 | 张秀兰 | Drug for treating thrombocytopenic purpura and preparation method thereof |
| CN103690692A (en) * | 2013-11-29 | 2014-04-02 | 周晨 | Traditional Chinese medicine formula for treating purpura |
| CN105055637A (en) * | 2015-08-28 | 2015-11-18 | 蒋玉群 | Traditional Chinese medicine composition for treating thrombocytopenic purpura |
| CN105663674A (en) * | 2016-01-27 | 2016-06-15 | 济南正骐生物科技有限公司 | Traditional Chinese medicine for treating thrombocytopenic purpura and preparation method of traditional Chinese medicine |
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