CN103860835B

CN103860835B - The veterinary drug of a kind of pure Chinese medicinal preparation

Info

Publication number: CN103860835B
Application number: CN201210524345.8A
Authority: CN
Inventors: 沈永强
Original assignee: GUANGDONG GAOSHAN ANIMAL MEDICINE CO Ltd
Current assignee: GUANGDONG GAOSHAN ANIMAL MEDICINE CO Ltd
Priority date: 2012-12-10
Filing date: 2012-12-10
Publication date: 2016-06-01
Anticipated expiration: 2032-12-10
Also published as: CN103860835A

Abstract

It is an object of the invention to propose one for preventing and treating the diseases such as an avian escherichia coli, pasteurellosis bacillus or Salmonellas, it is to increase the veterinary drug of the pure Chinese medicinal preparation of immunity of organisms. The veterinary drug of the pure Chinese medicinal preparation of the present invention is made up of the raw material of following weight part number proportioning: golden cypress 25��30, Root of Chinese Pulsatilla 20��25, Root and rhizome of Manyleaf Meadowrue 20��30, wrinkled giant hyssop 25��30, taraxacum 20��25, the banksia rose 15��20, Japanese Honeysuckle 25��30, squaw weed 15��20, the wind-weed 15��20, Chinese honey locust 15��20, Root of Indigowoad 35��40, Radix Glycyrrhizae 25��30, Leaf of Indigowoad 25��30, Herba Houttuyniae 30��35. Above-mentioned veterinary drug can effectively control the development of poultry epidemic situation, it is to increase the immunizing power of body, decreases the recurrence of epidemic disease, obtains good prevention effect. The more important thing is, above-mentioned various composition is Chinese medicine, has consumption few, clear curative effect, drug residue free, and toxic side effect is little, it is not easy to produces resistance, to features such as environmental health can not pollute, is very suitable for modern farming.

Description

The veterinary drug of a kind of pure Chinese medicinal preparation

Technical field

The invention belongs to veterinary drug technical field, be related specifically to one have inflammation antibacterial, anti-, toxinicide, anti-by force stress, anti-allergic, improve the veterinary drug of the pure Chinese medicinal preparation of the multiple efficacies such as immunity of organisms, for the control of the bacteriosises such as family's avian colibacillosis, salmonellosis, Bacillus pasteurii disease, salmonellosis.

Background technology

At present, along with aquaculture scale constantly expands, intensive degree improves constantly, poultry diease show multiple, take place frequently and complicated feature, livestock and poultry prevented and treated more difficult, causes huge financial loss to aquaculture, seriously affect culture benefit. Simultaneously, produce due to people's a large amount of resistance using chemical drug and microbiotic and cause in livestock and poultry disease control and prevention and to the pollution of environment, the food safety of people in the drug residue serious threat of livestock product, and these problems all affect health and the Sustainable development of industry.

Summary of the invention

It is an object of the invention to propose one for preventing and treating the diseases such as an avian escherichia coli, pasteurellosis bacillus or Salmonellas, it is to increase the veterinary drug of the pure Chinese medicinal preparation of immunity of organisms.

The veterinary drug of the pure Chinese medicinal preparation of the present invention is made up of the raw material of following weight part number proportioning: golden cypress 25��30, Root of Chinese Pulsatilla 20��25, Root and rhizome of Manyleaf Meadowrue 20��30, wrinkled giant hyssop 25��30, taraxacum 20��25, the banksia rose 15��20, Japanese Honeysuckle 25��30, squaw weed 15��20, the wind-weed 15��20, Chinese honey locust 15��20, Root of Indigowoad 35��40, Radix Glycyrrhizae 25��30, Leaf of Indigowoad 25��30, Herba Houttuyniae 30��35.

Further; it is that the super-fine powder grain of 3-5 ��m mixes that the veterinary drug of above-mentioned pure Chinese medicinal preparation makes particle fineness by described each raw material grinding mill; Chinese medicinal materials effective constituent after cell wall breaking discharges completely, is conducive to livestock and poultry body absorbing medicine, and its result for the treatment of has qualitative leap.

The pharmacology of above-mentioned each taste traditional Chinese medicine ingredients is as follows:

Golden cypress is the dry bark of rutaceae wampee or cork tree, its main component is Berberine, another containing multiple alkaloids such as Phellodendrine, magnoflorine, jateorhizine, palmatine, candicine, dauricines, there is the multiple efficacies such as antibacterium, antimycotic, antibechic, anti-hepatitis, on clinical, can be used for treatment bacillary dysentery, pneumonia, pulmonary tuberculosis, liver cirrhosis and hepatitis;

Root of Chinese Pulsatilla is the dry root of ranunculaceae plant Root of Chinese Pulsatilla, containing Root of Chinese Pulsatilla soap glucoside A, B, C, D, Pulsatilla camphor, the chemical compositions such as protoanemonin, there is the multiple effects such as ameba antibacterial, antiviral, anti-, calmness, analgesia, spasmolysis, clinical treat for the illness such as bacillary dysentery, anti-protozoal dysentery;

Horse hair is linked as rhizome and the root of Ranunculaceae thalictrum spp leafy Tang pine mushroom and plateau Tang pine mushroom, has effect of heat-clearing and damp-drying drug, removing toxic substances, for dysentery, enteritis, infectious hepatitis, and flu, measles, carbuncle swells sore furuncle, the treatment of conjunctivitis;

Wrinkled giant hyssop is Labiatae per nnial herb, all herbal medicine, containing the chemical composition such as volatile oil, flavonoid compound, has dispelling summer-heat from superficies of the body, effect of removing dampness to restore normal function of the stomach, modern study show wrinkled giant hyssop have antimycotic, antiviral, stimulate gastric mucosa, promote gastric secretion, digestive effect;

The dry full grass of Dandelion composite family per nnial herb, its sweet micro-hardship of the flat taste of property, there are clearing heat and detoxicating, dispersing swelling and dissipating binds and lactagogue effect, also have the effects such as diuresis, laxative, removing jaundice subcutaneous ulcer, profit courage, clinical for upper respiratory tract infection, acute mastitis swells and ache, gastritis, dysentery, the multiple disease such as acute bronchitis, urinary tract infections;

The banksia rose is the root of the feverfew banksia rose, and tool promoting the circulation of QI to relieve pain are regulated the flow of vital energy soothing the liver, and strong spleen disappears stagnant effect;

Japanese Honeysuckle is the flower that caprifoliaceae plant honeysuckle, lonicera hypoglauca miq, Lonicera confusa DC. or the dry flower of hair style honeysuckle or band are just opened. Japanese Honeysuckle contains chlorogenic acid, the number of chemical composition such as isochlorogenic acid and volatile oil. Modern pharmacological research shows that Japanese Honeysuckle has anti-multiple pathogenic microorganisms effect (various pathogens such as streptococcus aureus, dysentery bacterium all being had stronger restraining effect, the multiple pathogenic microorganisms such as Leptospira, influenza virus and pathogenic moulds are also had restraining effect), anti-inflammation and refrigeration function, booster immunization function effect, anti-endotoxin effect;

Squaw weed is cold in nature, bitter, has heat-clearing, and removing toxic substances, kills worm, bright order, control various acute inflammatory disease, typhoid fever, bacillary dysentery, lobar pneumonia, enteritis, jaundice, influenza, toxicaemia, all diseases such as septicemia;

The wind-weed is the rhizome of the liliaceous plant wind-weed, containing multiple containing number of chemical compositions such as soap glucoside, alkaloid, organic acid and wind-weed polysaccharide, there is resisting pathogenic microbes effect (as staphylococcus, Corynebacterium diphtheriae are had stronger restraining effect by wind-weed decoction, dysentery bacterium, paratyphosum Bacterium, intestinal bacteria, Bacillus subtilus, vibrio cholerae, Bacillus proteus, diphtheria corynebacterium, pneumococcus, beta hemolytic streptococcus, Candida albicans etc. also there is restraining effect in various degree), refrigeration function, the function of promoting digestion road, choleretic effect etc.;

Chinese honey locust is the fruit of leguminous plants Chinese honey locust tree, pod master is containing triterpenoid saponin, there is phlegm-dispelling functions, pathogenic bacterium in the blue negative intestines of the leather such as intestinal bacteria, dysentery bacterium, Bacillus proteus, Corynebacterium diphtheriae, paratyphosum Bacterium, Pseudomonas aeruginosa, vibrio cholerae are all had restraining effect;

Root of Indigowoad is the dry root of cruciferae isatis, and the blue root of ancient name for Chinese cabbage contains indigo, Indirubin, and the number of chemical compositions such as anthracene quinone class, have anti-bacteria and anti-virus, anti-Leptospira, detoxification, antitumor action, it is to increase the different physiological roles such as body's immunity;

Radix Glycyrrhizae is the dry root and rhizome of glycyrrhizic legume, glycyrrhiza inflate bat or glycyrrhiza glabra, main containing glycyrrhizin, useful gas bowl spares, relieving spasm to stop pain, moisten the lung and relieve the cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription effect, there is anti-inflammation, antiviral, anti-allergic and protecting liver and detoxication and strengthen the effects such as immunologic function;

Leaf of Indigowoad is the dry leave of cruciferae isatis, main containing chemical compositions such as indigo glucoside, Indirubins, research shows that Leaf of Indigowoad has resisting pathogenic microbes and also has restraining effect such as the anti-microbial effect of streptococcus aureus, alpha streptococcus, meningococcus, streptococcus pneumoniae, micrococcus catarrhalis, Corynebacterium diphtheriae, intestinal bacteria, hemophilus influenza, diphtheria corynebacterium and dysentery bacterium and to encephalitis b virus, mumps virus, influenza virus etc., anti-endotoxin effect, the effect of anti-inflammation, refrigeration function and raising body's immunity;

Herba Houttuyniae is the dry aerial parts of saururaceae plant houttuynia cordata, and full grass is containing volatile oil, and main effectively antimicrobial component is decanoylacetaldehyde, lauryl aldehyde, a-firpene and phantol. Function is clearing heat and detoxicating, removing pus and relieving carbuncle, inducing diuresis for treating stranguria syndrome. Modern pharmacological research is thought and is improved immunity of organisms, antibiosis and antiviral functions and diuretic properties.

By the flavour of a drug of the present invention composition and usage ratio, make ultrafine powder, on clinical for the intestinal bacteria of poultry, pasteurellosis bacillus, Salmonellas separately or polyinfection, can effectively control the development of epidemic situation, improve the immunizing power of body, decrease the recurrence of epidemic disease, obtain good prevention effect. The more important thing is, above-mentioned various composition is Chinese medicine, has consumption few, clear curative effect, drug residue free, and toxic side effect is little, it is not easy to produces resistance, to features such as environmental health can not pollute, is very suitable for modern farming.

Embodiment

Below by the description to embodiment, to the specific embodiment of the present invention as the effect and principle of work etc. of the mutual position between the shape of involved each component, structure, each several part and connection relation, each several part are described in further detail.

Embodiment 1:

It is that the super-fine powder grain of 3-5 ��m mixes: golden cypress 25, Root of Chinese Pulsatilla 20, Root and rhizome of Manyleaf Meadowrue 30, wrinkled giant hyssop 30, taraxacum 25, the banksia rose 15, Japanese Honeysuckle 25, squaw weed 20, the wind-weed 20, Chinese honey locust 15, Root of Indigowoad 35, Radix Glycyrrhizae 25, Leaf of Indigowoad 30, Herba Houttuyniae 35 that the veterinary drug of the pure Chinese medicinal preparation of the present embodiment makes particle fineness by the raw material grinding mill of following weight part number proportioning.

Following table is the test result measuring this prescription drug inhibition zone of encountered pathogenic microorganism on veterinary clinic by paper disk method:

Test organisms	Antibacterial circle diameter mm	Susceptibility
			Intestinal bacteria	17.80��0.45	Extremely sensitive
Pasteurellosis bacillus	18.75��0.60	Extremely sensitive
			Salmonellas	18.40��0.84	Extremely sensitive
Streptococcus aureus	17.60��0.53	Extremely sensitive

Note: antibacterial circle diameter is greater than 20mm and is judged to extremely responsive, is extremely sensitive between 20��14.5mm, is middle sensitivity between 14.5��10mm, and being less than 10.5mm is low sensitivity.

Above-mentioned test shows, pathogenic micro-organism common on veterinary clinic is had good restraining effect by this product.

Embodiment 2:

It is that the super-fine powder grain of 3-5 ��m mixes: golden cypress 30, Root of Chinese Pulsatilla 25, Root and rhizome of Manyleaf Meadowrue 250, wrinkled giant hyssop 28, taraxacum 25, the banksia rose 18, Japanese Honeysuckle 30, squaw weed 17, the wind-weed 19, Chinese honey locust 16, Root of Indigowoad 40, Radix Glycyrrhizae 30, Leaf of Indigowoad 26, Herba Houttuyniae 34 that the veterinary drug of the pure Chinese medicinal preparation of the present embodiment makes particle fineness by the raw material grinding mill of following weight part number proportioning.

Intestinal bacteria suffer to making a definite diagnosis in certain plant, the sick chicken of Salmonellas polyinfection adopts above-mentioned multi-usage veterinary drug to feed in the ratio mixed feeding of 2%, are used in conjunction 4 days, and result is as shown in the table:

Above-mentioned test shows, the sick chicken of trouble intestinal bacteria, Salmonellas polyinfection is had by this product responds well to treatment soon, has the feature that efficiency is high.

Embodiment 3:

It is that the super-fine powder grain of 3-5 ��m mixes: golden cypress 30, Root of Chinese Pulsatilla 20, Root and rhizome of Manyleaf Meadowrue 20, wrinkled giant hyssop 25, taraxacum 22, the banksia rose 18, Japanese Honeysuckle 28, squaw weed 18, the wind-weed 18, Chinese honey locust 15, Root of Indigowoad 37, Radix Glycyrrhizae 29, Leaf of Indigowoad 26, Herba Houttuyniae 32 that the veterinary drug of the pure Chinese medicinal preparation of the present embodiment makes particle fineness by the raw material grinding mill of following weight part number proportioning.

Certain plant to make a definite diagnosis suffer from pasteurellosis bacillus chicken mine massively with above-mentioned multi-usage veterinary drug in 2% ratio mixed feeding feed, be used in conjunction 4 days, result is as shown in the table:

Clinical test results shows: the pasteurellosis bacillus of chicken is infected by this product good curative effect.

Claims

1. the intestinal bacteria for poultry of a pure Chinese medicinal preparation, pasteurellosis bacillus, Salmonellas separately or the veterinary drug of polyinfection, it is characterised in that be made up of the raw material of following weight part number proportioning: golden cypress 25��30, Root of Chinese Pulsatilla 20��25, Root and rhizome of Manyleaf Meadowrue 20��30, wrinkled giant hyssop 25��30, taraxacum 20��25, the banksia rose 15��20, Japanese Honeysuckle 25��30, squaw weed 15��20, the wind-weed 15��20, Chinese honey locust 15��20, Root of Indigowoad 35��40, Radix Glycyrrhizae 25��30, Leaf of Indigowoad 25��30, Herba Houttuyniae 30��35.

2. the intestinal bacteria for poultry of pure Chinese medicinal preparation according to claim 1, pasteurellosis bacillus, Salmonellas separately or the veterinary drug of polyinfection, it is characterised in that making particle fineness by described each raw material grinding mill is that the super-fine powder grain of 3-5 ��m mixes.