CN103860650A - Medicament for treating rheumatism and rheumatoid and preparation method thereof - Google Patents
Medicament for treating rheumatism and rheumatoid and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a medicament for treating rheumatism and rheumatoid and a preparation method thereof, belonging to the technical field of Chinese herbal medicines for treating rheumatism and rheumatoid. Overcoming the defects of the prior art, the invention provides a pure Chinese medicine preparation which can effectively alleviate limb and joint swelling and pain caused by the rheumatism and rheumatoid diseases, symptoms can be relieved in a short period after the medicament is taken, the medicament products a desired effect after patients take one or two dosages generally, and people can take care of oneself and is basically healed after taking the medicament for three or five dosages. The medicament disclosed by the invention can be used for improving the life quality of rheumatism and rheumatoid patients and has no remarkable toxic or side effects found yet at present. According to the technical scheme, the medicament comprises the following raw materials in parts by weight: 9-21 parts of eucommia, 12-18 parts of cassis twigs, 12-21 parts of ephedra, 9-30 parts of medicinal cyathula root, 12-18 parts of frankincense, 12-18 parts of myrrh and 9-15 parts of nux vomica. The medicament disclosed by the invention can be quickly and effectively relieving the symptoms of the rheumatism and rheumatoid patients.
Description
Technical field
One of the present invention is treated rheumatism, rheumatoid medicine and preparation method thereof, belongs to the field of Chinese herbal medicine technology for the treatment of rheumatic and rheumatoid.
Background technology
Rheumatic arthritis is a kind of common acute or chronic ICT.Can repeatedly show effect and involve heart.Clinical miserable taking joint and muscle migration, heavily work, pain is as feature.Belong to allergic disease.One of main manifestations of rheumatic fever, mainly with febris acuta and arthralgia onset.Mostly think that at present it is human body autoimmune disease, also can be considered a kind of chronic syndrome, show as the nonspecific inflammation in periphery joint.Now diseased joints and surrounding tissue thereof present carrying out property destruction, and synovitis is outbreak repeatedly lastingly, the destruction that can cause intraarticular cartilage and bone, and joint function disturbance, even maimed.Vasculitis pathological changes is involved each organ of whole body, therefore primary disease is called again rheumatoid disease.The sickness rate women of rheumatoid arthritis is higher than male, and women is 2～3 times of male; The sickness rate of American-European countries is apparently higher than compatriots.The pathogeny of rheumatoid arthritis is not yet completely clear and definite.Rheumatoid arthritis be one with the closely-related disease of factor such as environment, antibacterial, virus, heredity, gonadal hormone and the neural mental status.
One, bacterium factors experimentation shows that A group B streptococcus and bacterium wall have the Peptidoglycan (Peptidoglycan) may be former for a lasting stimulation of RA morbidity, A group B streptococcus long-term existence becomes lasting antigen in body, stimulate body to produce antibody, immunological disease occurs and damage and cause a disease.The arthritis animal model of mycoplasma manufacturing is similar to people's RA, but does not produce people's the peculiar rheumatoid factor of RA (RF).In patient's RA joint fluid and synovial tissue, never found antibacterial or somatic antigen material, prompting antibacterial may be relevant with the onset of RA, but lack positive evidence.Two, viral factor RA is one of problem of noting of Chinese scholars with virus, the particularly relation of Epstein-Barr virus.Research shows, the arthritis due to ebv infection is different from RA, and patient RA has strong reaction to Epstein-Barr virus than normal person.In RA patients serum and synovial fluid, there is continuing anti EB virus--the membrane antigens antibody of high titre, but up to the present in RA patients serum, do not find eb nuclear antigen or housing antigen-antibody always.
Three, inherited genetic factors primary disease sickness rate in some family is higher, and in census of population, (HLA)-DR4 is relevant with RF positive patient to find human leukocyte antigen.HLA research finds that DW4 is relevant with the morbidity of RA, the 70%HLA-DW4 positive in patient, and patient has the tumor susceptibility gene in this site, and therefore heredity may play an important role in morbidity.
Four, gonadal hormone research shows that RA sickness rate men and women's ratio is 1:2-4, trimester of pregnancy the state of an illness alleviate, the women who the takes contraceptive minimizing of falling ill.Animal model shows that the female Mus of LEW/n is high to arthritic sensitivity, and male sickness rate is low, and after male Mus is processed through castrating or with beta estradiol, it is the same with female Mus that arthritic situation occurs for it, and illustrative hormone plays a role in RA morbidity.
Rheumatism belongs to " arthromyodynia ", " Plain Questions numbness opinion ": " wind, cold, wet three gas are mixed extremely, combined into numbness." a large amount of clinical experts confirmations, it is inadequate that list is controlled arthromyodynia from the wet opinion of wind and cold, many patients' thermal image instead resembles more than rheumatism is wet." Jin Guiyi ": " internal organs meridians, first have accumulation of heat, and multiple in the wet visitor of wind and cold, heat stagnated by cold, and gas must not lead to, the of a specified duration also heat-transformation of trembling with fear, numbness Xi and also vexed." visible ancients have had very deep understanding to rheumatism morbidity or the endogenous cause of ill, the exopathogenic factor that increase the weight of.Cold, humidity, fatigue, malnutrition, wound, Nervous and Mental Factors etc., be often the risk factor of primary disease, but before most of patients disease, the obvious inducement of normal nothing can be looked into.
At present treatment rheumatism, most of remission cycles of antirheumatic are long, and gastrointestinal symptom is obvious, patient be difficult to adhere to taking and also the more effect of side effect not ideal.
Summary of the invention
The present invention overcomes the deficiencies in the prior art, a kind of pure Chinese medicinal preparation is provided, can effectively alleviate limbs, arthroncus, pain because rheumatism, rheumatoid disease cause, after taking this medicine, the remission cycle is short, after generally taking one or two doses, obviously take effect, after taking three to five doses, live and can take care of oneself, be almost recovered.This Chinese patent medicine can improve the quality of life of rheumatism, rheumatoid patient, does not find at present obvious toxic and side effects.
For solving the problems of the technologies described above, the technical solution adopted in the present invention is: one is treated rheumatism, rheumatoid medicine, and the raw material adopting is according to following weight portion proportioning: Cortex Eucommiae 9-21 part, Ramulus Cinnamomi 12-18 part, Herba Ephedrae 12-21 part, Radix Cyathulae 9-30 part, Olibanum 12-18 part, Myrrha 12-18 part, Semen Strychni 9-15 part.
Described treatment rheumatism, antirheumatic are prepared according to following steps:
A, by described raw material according to weight portion: Cortex Eucommiae 9-21 part, Ramulus Cinnamomi 12-18 part, Herba Ephedrae 12-21 part, Radix Cyathulae 9-30 part, Olibanum 12-18 part, Myrrha 12-18 part, Semen Strychni 9-15 part, take;
B, by the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae and four kinds of Chinese medicines of Radix Cyathulae jointly with slow fire fry within 10-30 minute, dry for subsequent use;
C, by described Olibanum and Myrrha put into Testa Tritici slow fire fry dry after the flavescence of 10-45 wheat bran for subsequent use;
D, described Semen Strychni is first taken out to peeling after 3-10 minute with edible oil frying, adds slow fire in loess to fry 15-30 minute, sift out after making loess become taupe, with rice vinegar scald dry after surperficial native foam and oil stain for subsequent use;
E, by process the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae, Radix Cyathulae, Olibanum, Myrrha for subsequent use after pulverize, make honeyed pill with Mel together with Semen Strychni, make final drug.
The beneficial effect that compared with prior art the present invention has for: the present invention can be alleviated limbs, arthroncus, the pain because rheumatism, rheumatoid disease cause effectively, after taking this medicine, the remission cycle is short, after generally taking one or two doses, obviously take effect, after taking three to five doses, live and can take care of oneself, be almost recovered.This Chinese patent medicine can improve the quality of life of rheumatism, rheumatoid patient, does not find at present obvious toxic and side effects.
Prescription analysis of the present invention is: from ingredients, Herba Ephedrae, Ramulus Cinnamomi belong to Xin Wen and disperses medicine, have the effect of promoting the flow of QI in the collateral by warming the meridian stopping numbness pain; Radix Cyathulae, the Cortex Eucommiae belong to invigorating the liver and kidney, bone and muscle strengthening class medicine, have effect of bone and muscle strengthening, dampness removing dredging collateral; Herba Ephedrae, Radix Cyathulae itself all have effect of diuretic, and the pungent temperature of Herba Ephedrae is walked to alter, relieving the exterior syndrome by diaphoresis, and Radix Cyathulae priming is descending, eliminating blood stasis and inducing menstruation, the two compatibility uses the effect that can strengthen inducing diuresis to remove edema, easing joint movement.
Olibanum, Myrrha belong to medicine for promoting blood circulation and dispelling blood stasis thing, have effect of promoting blood circulation, dredging meridian and relieving pain, and the two Chang Xiangxu that is used as medicine is for using; " Records of Tradition Chinese and Western Medicine in Combination ": " Olibanum, Myrrha, two medicines use, for declaring the key medicine of logical internal organs, circulation meridians, therefore all pain of all heart stomach flank limbs joints all can be controlled it.Though be the product of opening, unlikely wasting QI-blood, really good medicine is also.”
Modern pharmacological research: pain is the important symptom of blood stasis, the Chinese medicine with promoting blood circulation and stopping pain effect has stronger analgesic activity; Drug for invigorating blood circulation and eliminating stasis can be synthetic by suppressing collagen, promotes it to decompose, and the connective tissue conversion of hypertrophy degeneration is absorbed, thereby suppress tissue abnormalities hypertrophy.
The traditional Chinese medical science thinks that arthromyodynia pathogenesis is for " wet three gas of wind and cold are mixed extremely; combined into numbness ", the medicine for the treatment of promoting the flow of QI in the collateral by warming the meridian, promoting blood circulation and stopping pain for multiselect, two groups of Herba Ephedrae, Ramulus Cinnamomi and Olibanum, Myrrhas will be just accord with this pathogenesis to coordination, embody the thought for the treatment of must aim at the pathogenesis of disease, there is effect of good warming the meridian and activating blood circulation, removing obstruction in the collateral to relieve pain.
Poisonnut is in topical class medicine, and because it is poisonous, it is loose that innerlich anwenden enters ball more, and the general 0.3-0.6g of dosage, has removing obstruction in the collateral to relieve pain, effect of mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis etc.
Modern pharmacological research shows that Semen Strychni topical class medicine has regulating action to reparation and the regeneration of tissue, obvious to tissue injury, fracture texts; Medicine for external use still can be urged softening, the absorption of collagen tissue, and the cicatrix of hyperplasia is had to repair.
Instructions of taking of the present invention is: every dose of medicine is a course for the treatment of, totally 25 days, every days two ball.As guiding drug (liquor, fermented wine), before taking medicine, first take a little wine cup Chinese liquor with Chinese liquor at every turn.Take medicine after meal, sooner or later respectively once, each ball.Clinical effectiveness: take medicine 3-5 days pain, pain and numbness alleviate, take one to two dose of medicine after clinical symptoms obviously alleviate, living after taking three to five doses can take care of oneself, and is almost recovered.
Clinical case
1, scape man 74 years old, foot lower limb numbness, pain, the change of weather increases the weight of 12 years.The remission after two doses of taking medicine, continues to take medicine at present.Its wife Cao female 73 years old, was diagnosed as rheumatoid disease before 6 years.Walk limited, hurt like hell.The symptom after two doses of taking medicine obviously alleviates and can walk, and short distance by bike, continues the consolidation of taking medicine at present.
2, Wang female 54 years old, suffers from rheumatism more than ten years, and each joint Changes in weather is stiff, pain.The symptom after three doses of taking medicine is obviously alleviated, and the life that continues to take medicine after three doses can take care of oneself and is almost recovered.
3, often certain male 68 years old, suffer from rheumatism many decades, each arthralgia Sciatica.Take medicine after potion and alleviate, take medicine and take care of oneself and be almost recovered after second dose.
4, Ji female 64 years old, suffers from rheumatism 8 years with numbness of hands and feet, arthralgia and symptoms of shoulder periarthritis.Take medicine after potion and obviously alleviate, the recovery from illness after 5 doses of taking medicine continues.Its daughter-in-law Hu female 42 years old, rheumatism is made a definite diagnosis with meeting cool numbness of hand wood, arthralgia, scapulohumeral periarthritis by hospital.Take medicine after two doses and obviously alleviate, continuously fully recover after taking 5 doses of medicines.
5, normal certain female 73 years old, make a definite diagnosis rheumatism with waist, move back, shoulder pain numbness.Take medicine after 5-6 agent and be almost recovered.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described.
Embodiment 1
A kind of preparation method for the treatment of rheumatism, antirheumatic is carried out according to following steps:
A, by described raw material according to weight portion: 21 parts of the Cortexs Eucommiae, 12 parts of Ramulus Cinnamomi, 21 parts, Herba Ephedrae, 9 parts of Radix Cyathulaes, 18 parts of Olibanums, 12 parts of Myrrhas, 15 parts of Semen Strychni, take;
B, by the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae and four kinds of Chinese medicines of Radix Cyathulae jointly with slow fire fry within 30 minutes, dry for subsequent use;
C, by described Olibanum and Myrrha put into Testa Tritici slow fire fry dry after 10 wheat bran flavescence for subsequent use;
D, described Semen Strychni is first taken out to peeling after 10 minutes with edible oil frying, adds slow fire in loess to fry 15 minutes, sift out after making loess become taupe, with rice vinegar scald dry after surperficial native foam and oil stain for subsequent use;
E, by process the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae, Radix Cyathulae, Olibanum, Myrrha for subsequent use after pulverize, make honeyed pill with Mel together with Semen Strychni, make final drug.
Embodiment 2
A kind of preparation method for the treatment of rheumatism, antirheumatic is carried out according to following steps:
A, by described raw material according to weight portion: 9 parts of the Cortexs Eucommiae, 18 parts of Ramulus Cinnamomi, 12 parts, Herba Ephedrae, 30 parts of Radix Cyathulaes, 12 parts of Olibanums, 18 parts of Myrrhas, 9 parts of Semen Strychni, take;
B, by the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae and four kinds of Chinese medicines of Radix Cyathulae jointly with slow fire fry within 10 minutes, dry for subsequent use;
C, by described Olibanum and Myrrha put into Testa Tritici slow fire fry dry after 45 wheat bran flavescence for subsequent use;
D, described Semen Strychni is first taken out to peeling after 3 minutes with edible oil frying, adds slow fire in loess to fry 30 minutes, sift out after making loess become taupe, with rice vinegar scald dry after surperficial native foam and oil stain for subsequent use;
E, by process the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae, Radix Cyathulae, Olibanum, Myrrha for subsequent use after pulverize, make honeyed pill with Mel together with Semen Strychni, make final drug.
Embodiment 3
A kind of preparation method for the treatment of rheumatism, antirheumatic is carried out according to following steps:
A, by described raw material according to weight portion: 15 parts of the Cortexs Eucommiae, 14 parts of Ramulus Cinnamomi, 20 parts, Herba Ephedrae, 15 parts of Radix Cyathulaes, 17 parts of Olibanums, 17 parts of Myrrhas, 12 parts of Semen Strychni, take;
B, by the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae and four kinds of Chinese medicines of Radix Cyathulae jointly with slow fire fry within 20 minutes, dry for subsequent use;
C, by described Olibanum and Myrrha put into Testa Tritici slow fire fry dry after 20 wheat bran flavescence for subsequent use;
D, described Semen Strychni is first decocted after deep fry for five minutes and is taken out peeling with edible oil, add slow fire in loess to fry 20 minutes, sift out after making loess become taupe, with rice vinegar scald dry after surperficial native foam and oil stain for subsequent use;
E, by process the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae, Radix Cyathulae, Olibanum, Myrrha for subsequent use after pulverize, make honeyed pill with Mel together with Semen Strychni, make final drug.
Embodiment 4
A kind of preparation method for the treatment of rheumatism, antirheumatic is carried out according to following steps:
A, by described raw material according to weight portion: 18 parts of the Cortexs Eucommiae, 16 parts of Ramulus Cinnamomi, 15 parts, Herba Ephedrae, 25 parts of Radix Cyathulaes, 14 parts of Olibanums, 15 parts of Myrrhas, 10 parts of Semen Strychni, take;
B, by the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae and four kinds of Chinese medicines of Radix Cyathulae jointly with slow fire fry within 25 minutes, dry for subsequent use;
C, by described Olibanum and Myrrha put into Testa Tritici slow fire fry dry after 40 wheat bran flavescence for subsequent use;
D, described Semen Strychni is first taken out to peeling after 7 minutes with edible oil frying, adds slow fire in loess to fry 25 minutes, sift out after making loess become taupe, with rice vinegar scald dry after surperficial native foam and oil stain for subsequent use;
E, by process the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae, Radix Cyathulae, Olibanum, Myrrha for subsequent use after pulverize, make honeyed pill with Mel together with Semen Strychni, make final drug.
Embodiment 5
A kind of preparation method for the treatment of rheumatism, antirheumatic is carried out according to following steps:
A, by described raw material according to weight portion: 20 parts of the Cortexs Eucommiae, 17 parts of Ramulus Cinnamomi, 13 parts, Herba Ephedrae, 28 parts of Radix Cyathulaes, 15 parts of Olibanums, 15 parts of Myrrhas, 11 parts of Semen Strychni, take;
B, by the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae and four kinds of Chinese medicines of Radix Cyathulae jointly with slow fire fry within 15 minutes, dry for subsequent use;
C, by described Olibanum and Myrrha put into Testa Tritici slow fire fry dry after 15 wheat bran flavescence for subsequent use;
D, described Semen Strychni is first taken out to peeling after 4 minutes with edible oil frying, adds slow fire in loess to fry 22 minutes, sift out after making loess become taupe, with rice vinegar scald dry after surperficial native foam and oil stain for subsequent use;
E, by process the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae, Radix Cyathulae, Olibanum, Myrrha for subsequent use after pulverize, make honeyed pill with Mel together with Semen Strychni, make final drug.
Mel, as by effect bonding described medicine, is made ball by medicine.
The present invention can summarize with other the concrete form without prejudice to spirit of the present invention or principal character.Therefore, no matter from which point, above-mentioned embodiment of the present invention all can only think explanation of the present invention can not limit invention, claims have been pointed out scope of the present invention, and scope of the present invention is not pointed out in above-mentioned explanation, therefore, any variation in implication and the scope suitable with claims of the present invention, all should think to be included in the scope of claims.
Claims (2)
1. treatment rheumatism, a rheumatoid medicine, is characterized in that adopted raw material is according to following weight portion proportioning: Cortex Eucommiae 9-21 part, Ramulus Cinnamomi 12-18 part, Herba Ephedrae 12-21 part, Radix Cyathulae 9-30 part, Olibanum 12-18 part, Myrrha 12-18 part, Semen Strychni 9-15 part.
2. a preparation method for treatment rheumatism according to claim 1, antirheumatic, is characterized in that carrying out according to following steps:
A, by described raw material according to weight portion: Cortex Eucommiae 9-21 part, Ramulus Cinnamomi 12-18 part, Herba Ephedrae 12-21 part, Radix Cyathulae 9-30 part, Olibanum 12-18 part, Myrrha 12-18 part, Semen Strychni 9-15 part, take;
B, by the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae and four kinds of Chinese medicines of Radix Cyathulae jointly with slow fire fry within 10-30 minute, dry for subsequent use;
C, by described Olibanum and Myrrha put into Testa Tritici slow fire fry dry after the flavescence of 10-45 wheat bran for subsequent use;
D, described Semen Strychni is first taken out to peeling after 3-10 minute with edible oil frying, adds slow fire in loess to fry 15-30 minute, sift out after making loess become taupe, with rice vinegar scald dry after surperficial native foam and oil stain for subsequent use;
E, by process the described Cortex Eucommiae, Ramulus Cinnamomi, Herba Ephedrae, Radix Cyathulae, Olibanum, Myrrha for subsequent use after pulverize, make honeyed pill with Mel together with Semen Strychni, make final drug.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104095912A (en) * | 2014-06-26 | 2014-10-15 | 华东理工大学 | Traditional Chinese medicine formula for treating rheumatism bone disease and preparation method of Chinese patent medicine of traditional Chinese medicine formula |
| CN104666673A (en) * | 2015-03-02 | 2015-06-03 | 郭信涛 | Traditional Chinese medicine composition and self-heating protective equipment |
| CN105853927A (en) * | 2016-05-24 | 2016-08-17 | 王桂英 | Traditional Chinese medicine for treating rheumatic arthralgia |
| CN108379459A (en) * | 2018-04-04 | 2018-08-10 | 安徽颐生堂中药饮片有限公司 | A kind of Processed Product of Rhizoma Gastrodiae and preparation method thereof |
| CN108498634A (en) * | 2017-11-01 | 2018-09-07 | 王健民 | A kind of externally applied drug of rheumatoid arthritis and its preparation method and application |
-
2014
- 2014-02-18 CN CN201410054510.7A patent/CN103860650A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104095912A (en) * | 2014-06-26 | 2014-10-15 | 华东理工大学 | Traditional Chinese medicine formula for treating rheumatism bone disease and preparation method of Chinese patent medicine of traditional Chinese medicine formula |
| CN104095912B (en) * | 2014-06-26 | 2018-06-26 | 华东理工大学 | Treat the preparation method of the Chinese patent drug of rheumatism bone disease |
| CN104666673A (en) * | 2015-03-02 | 2015-06-03 | 郭信涛 | Traditional Chinese medicine composition and self-heating protective equipment |
| CN105853927A (en) * | 2016-05-24 | 2016-08-17 | 王桂英 | Traditional Chinese medicine for treating rheumatic arthralgia |
| CN108498634A (en) * | 2017-11-01 | 2018-09-07 | 王健民 | A kind of externally applied drug of rheumatoid arthritis and its preparation method and application |
| CN108379459A (en) * | 2018-04-04 | 2018-08-10 | 安徽颐生堂中药饮片有限公司 | A kind of Processed Product of Rhizoma Gastrodiae and preparation method thereof |
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Application publication date: 20140618 |