CN103830622A - Traditional Chinese medicine composition for treating gastric erosion - Google Patents

Traditional Chinese medicine composition for treating gastric erosion Download PDF

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Publication number
CN103830622A
CN103830622A CN201410115494.8A CN201410115494A CN103830622A CN 103830622 A CN103830622 A CN 103830622A CN 201410115494 A CN201410115494 A CN 201410115494A CN 103830622 A CN103830622 A CN 103830622A
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parts
radix
rhizoma
chinese medicine
traditional chinese
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陈晓明
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BENGBU HUOHE PHARMACEUTICAL Co Ltd
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BENGBU HUOHE PHARMACEUTICAL Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine composition for treating gastric erosion. The composition is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 5-15 parts of scutellaria baicalensis, 1-5 parts of coptis chinensis, 10-20 parts of hedyotis diffusa, 10-20 parts of immature bitter orange, 5-15 parts of rhizoma pinellinae praeparata, 5-15 parts of dried tangerine or orange peel, 10-20 parts of mangnolia officinalis, 20-40 parts of codonopsis pilosula, 5-15 parts of atractylodes macrocephala, 10-20 parts of poria, 3-10 parts of liquorice, 20-40 parts of astragalus membranaceus, 5-15 parts of the shell of areca nut, 20-40 parts of Chinese yam, 20-40 parts of semen coicis and 5-15 parts of radix hedysari. The composition is prepared from pure traditional Chinese medicines, has the effects of clearing away heat and toxic materials, relieving sore and generating muscles, relieving pain and removing stasis, tonifying qi and tonifying spleen, and the like, and has the advantages that a remarkable curative effect on gastric erosion is achieved, both symptoms and root causes are treated, no toxic or side effect is caused, the disease is unlikely to relapse after being healed, and the like.

Description

A kind of Chinese medicine composition for the treatment of gastric erosion
Technical field:
The present invention relates to tcm field, particularly a kind of Chinese medicine composition for the treatment of gastric erosion.
Background technology:
Gastric erosion is gastric ulcer.Peptic Ulcers or peptic ulcer are a kind of common digestive tract disease, can betide esophagus, stomach or duodenum, also can betide near stomach-intestinal anastomosis mouth or in the diverticulum that contains gastric mucosa, because gastric ulcer and duodenal ulcer are the most common, therefore general so-called peptic ulcer refers to gastric ulcer and duodenal ulcer.Why it is referred to as peptic ulcer, because previously think that gastric ulcer and duodenal ulcer are due to gastric acid and pepsin, mucosa autodigestion to be formed, in fact gastric acid and pepsin are the one of the main reasons of ulcer, also have other reasons can form peptic ulcer.Mainly use as sucralfate, bismuth, carbenoxolone etc. and anti-body element class medicine for the treatment doctor trained in Western medicine of primary disease at present, and these medicines of long-term taking can bring larger toxic and side effects and financial burden to patient.
Summary of the invention:
The present invention is in order to make up the deficiency to gastric erosion treatment in prior art, a kind of Chinese medicine composition for the treatment of gastric erosion is provided, the present invention adopts pure Chinese medicine to make, and has heat-clearing and toxic substances removing, holder skin ulcer granulation promoting, medicinal powder for relieving pain knot, the effects such as air making-up and spleen enlivening, have curative effect to gastric erosion treatment obvious, treating both the principal and secondary aspects of a disease, have no side effect, and be difficult for the advantages such as recurrence after curing.
The invention provides following technical scheme:
Treat a Chinese medicine composition for gastric erosion, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Radix Scutellariae 5-15 part, Rhizoma Coptidis 1-5 part, Agkistrodon Rhizoma et radix valerianae 10-20 part, Fructus Aurantii Immaturus 10-20 part, Rhizoma Pinelliae Preparatum 5-15 part, Pericarpium Citri Reticulatae 5-15 part, Cortex Magnoliae Officinalis 10-20 part, Radix Codonopsis 20-40 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Poria 10-20 part, Radix Glycyrrhizae 3-10 part, Radix Astragali 20-40 part, Pericarpium Arecae 5-15 part, Rhizoma Dioscoreae 20-40 part, Semen Coicis 20-40 part, Radix Hedysari 5-15 part.
Formula optimization is:
9 parts of Radix Scutellariaes, 3 parts of Rhizoma Coptidis, 12 parts of Agkistrodon Rhizoma et radix valerianaes, 12 parts of Fructus Aurantii Immaturuss, 10 parts of Rhizoma Pinelliae Preparatum, 10 parts of Pericarpium Citri Reticulataes, 15 parts of Cortex Magnoliae Officinalis, 25 parts of Radix Codonopsis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Poria, 6 parts, Radix Glycyrrhizae, 30 parts of the Radixs Astragali, 10 parts of Pericarpium Arecae, 30 parts of Rhizoma Dioscoreaes, 30 parts of Semen Coiciss, 10 parts of Radix Hedysari.
Preparation method:
Radix Scutellariae, Fructus Aurantii Immaturus, Poria, Rhizoma Dioscoreae, Semen Coicis are carried out to water extraction, and after water extraction, after filtering medicinal residues, medicinal liquid is for subsequent use.Soak other raw material by the clean water of 6 times of weight portions then decocting 2 times for 2 hours, decoct for the first time 60 minutes, decoct for the second time 40 minutes, merge decoction liquor elimination medicinal residues twice, with water extraction liquid for subsequent use or and after, 50 DEG C of concentrating under reduced pressure are dry, become after dry extract, be ground into 200 order fine powders, sterilizing, fill capsule or make tablet under gnotobasis.
Instructions of taking:
Morning, noon and afternoon every day take 3 times with meal, and each 10 grams, taking medicine continuously one week is a course for the treatment of.
Below effect to forming raw material of Chinese medicine of the present invention and the explanation of pharmacology:
Radix Scutellariae another name Radix Scutellariae, tsuchikane tea root, bitter in the mouth, cold in nature, returns lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.Can heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Research shows, the effect such as that this product has is antibacterial, antiviral, antiinflammatory antiallergic action, and can not develop immunity to drugs.
Rhizoma Coptidis: bitter in the mouth, cold in nature, GUIXIN, liver, stomach, large intestine channel.There is heat clearing and damp drying, effect of eliminating fire and detoxication.Research shows: this product also has the effects such as antibacterial, antivirus action, antiinflammatory, diarrhea, refrigeration function, blood sugar lowering, blood fat reducing, antioxidation.In addition blood system also had to a certain effect.
Herba Hedyotidis Diffusae: come from Shennong's Herbal bitter in the mouth, light, cold in nature.Return stomach warp.Main effect is heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness.Outstanding kind treatment all kinds inflammation.Zoopery shows that this product can strengthen humoral immune function, and hemolysis plaque digital display work in mouse spleen is increased.
Fructus Aurantii Immaturus: bitter in the mouth, pungent, cold in nature.Return spleen, stomach, liver, heart channel.There is soothing the liver dispelling the stagnated QI, the effect such as removing food stagnancyization is stagnant.Record in tool " medicine justice ": " Fructus Aurantii Immaturus is specially let out excess of the stomach, convinces hard knot by patient analysis, therefore that the main middle part of gastric cavity to control blood system, is treated between umbilicus clothes is real full, expectorant addiction, dispels and cut off the water, by dyspepsia, broken blocked-up chest, relieving constipation is closed, non-this can not be also." experiment shows: the decoct of this product has the effect that suppresses intestinal and smooth muscle of bile vesica, secretion that can facilitating digestion liquid and get rid of the effects such as enteral pneumatosis.
Rhizoma Pinelliae Preparatum: acrid in the mouth, warm in nature.Return lung, spleen, stomach warp.There is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, the effects such as reducing swelling and alleviating pain.This product also has the effects such as antiulcer, blood fat reducing, tranquilizing soporific, antitumor, removing toxic substances antiinflammatory.
Pericarpium Citri Reticulatae is the dry mature skin of rutaceae orange and variety thereof.Peel is with Chen Zheliang, therefore named.Medical material is divided into " Pericarpium Citri Reticulatae " and " Pericarpium citri reticuatae chachiensis ".Bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.There is regulating qi-flowing for strengthening spleen, in tune, dampness, the effect such as reduce phlegm.
Cortex Magnoliae Officinalis: bitter in the mouth, pungent, warm in nature.Return spleen, stomach, large intestine channel.There is circulation of qi promoting removing food stagnancy, dampness except effects such as full, lowering the adverse QI to relieve asthmas.Experiment shows: this product decoct has antibacterial action to multiple pathogenic bacteria, particularly the strongest to Staphylococcus albus, bacillus subtilis, colibacillary effect.
Radix Codonopsis: sweet in the mouth, micro-acid, property is flat.Return spleen, lung meridian.There is invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.This product has enhancing human body immunity function, strengthens hemopoietic function, anti-stress, heart tonifying, shock, adjusting blood pressure, resists myocardial ischemia and the effect such as anticoagulant.Also there is the effects such as Fructus Alpiniae Oxyphyllae, calmness, hypnosis, convulsion.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.There is air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive effect.Research shows: the effect such as this product decoct has Gastrointestinal motility adjustment, diuresis, blood sugar lowering, protects the liver, anticoagulant, blood vessel dilating, blood pressure lowering, anti-bacteria, its contained Rhizoma Atractylodis polysaccharide has effect of enhancing immunity.Zoopery shows: Rhizoma Atractylodis Macrocephalae extract, to animal water-immersion restraint stress ulcer, has remarkable inhibition.
Poria, in " Bencao Jingshu ", record: " Poria, its sweet in the mouth is flat, and property is nontoxic, enters brothers few cloudy, the large sun of hands, lunar, the Yangming Channel of foot, the YIN aspect of YANG is also.This product has promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, and mind tranquilizing and the heart calming, relieves internal heat anticancer.The property of medicine is gentle, dampness removing and do not hinder healthy energy.In this product contained pachymic acid, pachyman have enhancing immunity, antitumor, calmness, blood sugar lowering, antibacterial, prevent that hepatic necrosis from regulating the effects such as immunologic function.
Radix Glycyrrhizae: sweet in the mouth, property is flat.Enter spleen, stomach, lung meridian.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.This product can be calm, protect the liver, removing toxic substances, the effect such as antipyretic, and in this product, contained glycyrrhizin, liquirtin etc. has spasmolytic, suppresses the effects such as gastric secretion, antiulcer.
The Radix Astragali: sweet in the mouth, slightly warm in nature.Return lung, spleen, liver, kidney channel.There is enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.For after skin infection diabrosis, do not close up for a long time, there is the effect of promoting tissue regeneration and wound healing.
Pericarpium Arecae: acrid in the mouth, slightly warm in nature.Return stomach, large intestine, small intestine meridian.There is therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, the effects such as line water detumescence.Research shows: the decoct of this product has obvious stimulation to intestinal smooth.
Rhizoma Dioscoreae: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.There is supplementing QI and nourishing YIN, spleen reinforcing lung kidney, the effects such as treating spontaneous emission and leukorrhagia.This product has the effect that suppresses generation to mutant cell.Can also prevent and treat Human Lipid Metabolism abnormal, and arteriosclerosis, to safeguarding that insulin normal function also has certain effect, there is enhancing body immunity, beneficial heart and tranquilizing mind, rather coughs the effects such as Dingchuan, slow down aging.
Semen Coicis: sweet in the mouth, cold in nature.Return spleen, stomach, lung meridian.There is promoting diuresis to eliminate damp pathogen, invigorating the spleen to arrest diarrhea, heat clearing away is got rid of, the effects such as eliminating impediment.In Compendium of Material Medica for the record of this product: " positive bright medicine also, can invigorating spleen and reinforcing stomach.Reinforcing the mother-organ for treating deficiency of the son-organ, therefore consumptive lung disease, lung abscess are used it.The disease of muscles and bones, taking Zhi Yangming as this, therefore contracture muscular contracture migratory arthralgia person uses it.Soil can win water dehumidifying, thus have loose bowels edema with it ".The ethanol extract of this product has anticancer, antibacterial effect.
Radix Hedysari: sweet in the mouth, warm in nature.Return lung, spleen channel.There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, the effects such as expelling pus and promoting granulation.The effects such as this product also has cardiac function enhancing, blood vessel dilating, improves blood circulation, blood pressure lowering, calmness, blood sugar lowering, inhibition pathogenic bacteria.
The present invention adopts pure Chinese medicine to make, and has heat-clearing and toxic substances removing, holder skin ulcer granulation promoting, and medicinal powder for relieving pain knot, the effects such as air making-up and spleen enlivening, to gastric erosion, to have curative effect obvious in treatment, and treating both the principal and secondary aspects of a disease, has no side effect, and is difficult for the advantages such as recurrence after curing.
Detailed description of the invention:
Embodiment 1: a kind of Chinese medicine composition for the treatment of gastric erosion, it is characterized in that being made up of the raw material of Chinese medicine of following weight proportion: 9 parts of Radix Scutellariaes, 3 parts of Rhizoma Coptidis, 12 parts of Agkistrodon Rhizoma et radix valerianaes, 12 parts of Fructus Aurantii Immaturuss, 10 parts of Rhizoma Pinelliae Preparatum, 10 parts of Pericarpium Citri Reticulataes, 15 parts of Cortex Magnoliae Officinalis, 25 parts of Radix Codonopsis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Poria, 6 parts, Radix Glycyrrhizae, 30 parts of the Radixs Astragali, 10 parts of Pericarpium Arecae, 30 parts of Rhizoma Dioscoreaes, 30 parts of Semen Coiciss, 10 parts of Radix Hedysari.
Preparation method:
Radix Scutellariae, Fructus Aurantii Immaturus, Poria, Rhizoma Dioscoreae, Semen Coicis are carried out to water extraction, and after water extraction, after filtering medicinal residues, medicinal liquid is for subsequent use.Soak other raw material by the clean water of 6 times of weight portions then decocting 2 times for 2 hours, decoct for the first time 60 minutes, decoct for the second time 40 minutes, merge decoction liquor elimination medicinal residues twice, with water extraction liquid for subsequent use or and after, 50 DEG C of concentrating under reduced pressure are dry, become after dry extract, be ground into 200 order fine powders, sterilizing, fill capsule or make tablet under gnotobasis.
Embodiment 2:
Treat a Chinese medicine composition for gastric erosion, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 7 parts of Radix Scutellariaes, 3 parts of Rhizoma Coptidis, 15 parts of Agkistrodon Rhizoma et radix valerianaes, 15 parts of Fructus Aurantii Immaturuss, 8 parts of Rhizoma Pinelliae Preparatum, 12 parts of Pericarpium Citri Reticulataes, 18 parts of Cortex Magnoliae Officinalis, 30 parts of Radix Codonopsis, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 18 parts of Poria, 8 parts, Radix Glycyrrhizae, 30 parts of the Radixs Astragali, 12 parts of Pericarpium Arecae, 30 parts of Rhizoma Dioscoreaes, 30 parts of Semen Coiciss, 12 parts of Radix Hedysari.
Preparation method:
Radix Scutellariae, Fructus Aurantii Immaturus, Poria, Rhizoma Dioscoreae, Semen Coicis are carried out to water extraction, and after water extraction, after filtering medicinal residues, medicinal liquid is for subsequent use.Soak other raw material by the clean water of 6 times of weight portions then decocting 2 times for 2 hours, decoct for the first time 60 minutes, decoct for the second time 40 minutes, merge decoction liquor elimination medicinal residues twice, with water extraction liquid for subsequent use or and after, 50 DEG C of concentrating under reduced pressure are dry, become after dry extract, be ground into 200 order fine powders, sterilizing, fill capsule or make tablet under gnotobasis.
Embodiment 3:
Treat a Chinese medicine composition for gastric erosion, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 12 parts of Radix Scutellariaes, 5 parts of Rhizoma Coptidis, 16 parts of Agkistrodon Rhizoma et radix valerianaes, 15 parts of Fructus Aurantii Immaturuss, 13 parts of Rhizoma Pinelliae Preparatum, 13 parts of Pericarpium Citri Reticulataes, 15 parts of Cortex Magnoliae Officinalis, 35 parts of Radix Codonopsis, 14 parts of the Rhizoma Atractylodis Macrocephalaes, 18 parts of Poria, 8 parts, Radix Glycyrrhizae, 35 parts of the Radixs Astragali, 15 parts of Pericarpium Arecae, 40 parts of Rhizoma Dioscoreaes, 35 parts of Semen Coiciss, 14 parts of Radix Hedysari.
Preparation method:
Radix Scutellariae, Fructus Aurantii Immaturus, Poria, Rhizoma Dioscoreae, Semen Coicis are carried out to water extraction, and after water extraction, after filtering medicinal residues, medicinal liquid is for subsequent use.Soak other raw material by the clean water of 6 times of weight portions then decocting 2 times for 2 hours, decoct for the first time 60 minutes, decoct for the second time 40 minutes, merge decoction liquor elimination medicinal residues twice, with water extraction liquid for subsequent use or and after, 50 DEG C of concentrating under reduced pressure are dry, become after dry extract, be ground into 200 order fine powders, sterilizing, fill capsule or make tablet under gnotobasis.
General clinical data:
The 120 routine patient medical record that below use inventor to collect, the invention will be further described, wherein male's 64 examples, women's 56 examples, oldest 65, and minimum 22 years old, the course of disease was the longest 7 years, the shortest half a year.
Efficacy determination:
Cure: stomach pain, abdominal distention, belch, the transference cure such as feel sick, gastroscopy stomach is without extremely, and it is normal that physical skills is recovered.
Effective: above-mentioned symptom all takes a turn for the better to some extent.
Invalid: to be not improved through before after the taking medicine of a 4-6 the course for the treatment of symptom and treatment.
Therapeutic outcome:
Cure 56 examples, effective 55 examples, no effect 9, total effective rate is 92.5%.
Model case:
Case 1: patient Wang, man 42 years old, is diagnosed as gastric ulcer through hospital, bad while treating for many years symptom fashion, and over 2008 years, here is medical.Use after 6 courses for the treatment of of traditional Chinese medicine composition for treating in embodiment 1, the transference cure of all stomach discomfort, through the healing of gastroscopy stomach ulcer surface, it is normal that coat of the stomach recovers.
Case 2: patient Yang, female 60 years old, at the bottom of stomach, erosion is bad when symptom fashion for many years, 2009 because using cool milk to cause vomiting, belch, sour regurgitation, stomach to have cusalgia sense, find through gastroscope: antrum or stomach angle mucous hyperemia oedema, there is the erosion of patch shape, peristole is normal.Use after 4 courses for the treatment of of traditional Chinese medicine composition for treating in embodiment 1, the transference cure of all stomach discomfort, reduces 75% through gastroscopy stomach ulcer area, after 6 courses for the treatment of of continuing to take medicine, fully recovers.
Case 3: patient what so-and-so, 27 years old, truck driver suffered from gastric ulcer, and due to work relationship all the year round diet, live irregular, stomach causalgia sense in 2010 aggravation, and the symptom such as belch, acid regurgitation increases the weight of, and had a strong impact on work.After taking 4 courses for the treatment of of medicine of the present invention, fully recover.

Claims (2)

1. treat a Chinese medicine composition for gastric erosion, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Radix Scutellariae 5-15 part, Rhizoma Coptidis 1-5 part, Agkistrodon Rhizoma et radix valerianae 10-20 part, Fructus Aurantii Immaturus 10-20 part, Rhizoma Pinelliae Preparatum 5-15 part, Pericarpium Citri Reticulatae 5-15 part, Cortex Magnoliae Officinalis 10-20 part, Radix Codonopsis 20-40 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Poria 10-20 part, Radix Glycyrrhizae 3-10 part, Radix Astragali 20-40 part, Pericarpium Arecae 5-15 part, Rhizoma Dioscoreae 20-40 part, Semen Coicis 20-40 part, Radix Hedysari 5-15 part.
2. according to a kind of Chinese medicine composition for the treatment of gastric erosion described in claim 1, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 9 parts of Radix Scutellariaes, 3 parts of Rhizoma Coptidis, 12 parts of Agkistrodon Rhizoma et radix valerianaes, 12 parts of Fructus Aurantii Immaturuss, 10 parts of Rhizoma Pinelliae Preparatum, 10 parts of Pericarpium Citri Reticulataes, 15 parts of Cortex Magnoliae Officinalis, 25 parts of Radix Codonopsis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Poria, 6 parts, Radix Glycyrrhizae, 30 parts of the Radixs Astragali, 10 parts of Pericarpium Arecae, 30 parts of Rhizoma Dioscoreaes, 30 parts of Semen Coiciss, 10 parts of Radix Hedysari.
CN201410115494.8A 2014-03-26 2014-03-26 Traditional Chinese medicine composition for treating gastric erosion Pending CN103830622A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108969688A (en) * 2018-09-20 2018-12-11 江西景德中药股份有限公司 Invigorating spleen for diuresis, Chinese medicine composition of detumescence and apocenosis and its preparation method and application

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101757576A (en) * 2008-10-27 2010-06-30 薛立英 Traditional Chinese medicine preparation

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101757576A (en) * 2008-10-27 2010-06-30 薛立英 Traditional Chinese medicine preparation

Non-Patent Citations (1)

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Title
陈育忠等: "基于文献的胃溃疡中医用药规律研究", 《中医药信息》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108969688A (en) * 2018-09-20 2018-12-11 江西景德中药股份有限公司 Invigorating spleen for diuresis, Chinese medicine composition of detumescence and apocenosis and its preparation method and application

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Application publication date: 20140604