CN103816179A - Disinfecting liquid, medical compound iodine sterile cotton ball prepared from disinfecting liquid, and corresponding preparation method - Google Patents
Disinfecting liquid, medical compound iodine sterile cotton ball prepared from disinfecting liquid, and corresponding preparation method Download PDFInfo
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- CN103816179A CN103816179A CN201310658586.6A CN201310658586A CN103816179A CN 103816179 A CN103816179 A CN 103816179A CN 201310658586 A CN201310658586 A CN 201310658586A CN 103816179 A CN103816179 A CN 103816179A
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Abstract
The invention discloses a disinfecting liquid which comprises the following components according to weight ratio of 0.23-0.25g of effective iodine, 0.13-0.15g of chlorhexidine, 0.008-0.012g of alkylphenol polyoxyethylene, 0.08-0.12g of MDZ0 water based defoamer, 0.06-0.07g of Tx-10 alkyl acid, and the balance of deionized water solvent in 100ml of the disinfecting liquid. The disinfecting liquid is taken as a basis, a medical compound iodine sterile cotton ball (swab) with the disinfecting rate up to 99.99%-100% is further prepared, is a top product used for disinfection in the medical field, and is also a latest generation of disinfecting product in the current medical field. According to the disinfecting liquid provided by the invention, the labor intensity of a nurse is alleviated, the speed of giving an injection to a patient is increased, more importantly, the occurrence of mistaken disinfection is avoided, and the safety of the patient is guaranteed. The disinfecting rate is of epoch-making significances in comparison with that of the existing disinfection, and the medical value of the disinfecting liquid is more remarkable.
Description
Technical field
The present invention relates to a kind of compound iodine medical disinfecting cotton ball, specifically, relate to a kind of compound iodine medical disinfecting cotton ball of sterilizing medicinal liquid and make and corresponding preparation method
.
Background technology
To the sterilization of human body skin, often use sterilized cotton ball or cotton swab, and the sterilization method of standard, as hospital nurse sterilization, generally includes two steps: the first step, is used and carry out wiping skin containing the absorbent cotton of iodine tincture, to reach the object of disinfection; Second step, for eliminating the zest of iodine tincture to human body skin, uses alcoholic absorbent cotton to carry out wiping for the second time, dilutes the iodine tincture content on skin by ethanol, i.e. de-iodine.That is to say, hospital nurse is sterilized to patient conventionally, need to implement disinfecting process twice to patient's skin, this process is not only loaded down with trivial details, also increased the labor intensity of nurse job, and more time, especially in the busy working time, nurse is easy to forget and carries out second step, some irresponsible nurse even can directly not carry out second step, thus, has not only reduced Disinfection Effect, also can increase patient's misery, even relate to patient's life security.
The patent No. is that the patent of 00111557.X discloses a kind of medical disinfecting cotton ball and preparation method, it discloses a kind of sterilization medicinal liquid being made up of available iodine, hibitane, polyvinyl chloride nonylphenolether and distilled water, and the sterilized cotton ball of making, the more conventional sterilized cotton ball of sterilized cotton ball that this sterilization medicinal liquid is made has very significant effect aspect disinfection, through clinical practice and professional institution's test, its sterilizing rate reaches as high as 99.32%.From being the consideration of patient health angle, the highest standard that people pursue is 99.99%-100% sterilization, although this pursuit is almost difficult to realize, improving as much as possible sterilizing rate still becomes emphasis and the target of the lasting research of each research institution.
Summary of the invention
The object of the present invention is to provide a kind of sterilized cotton ball of sterilizing medicinal liquid and making, solve the problem that disinfecting process is loaded down with trivial details, Disinfection Effect is not high enough that prior art exists.
To achieve these goals, the technical solution used in the present invention is as follows:
A kind of sterilization medicinal liquid, its component and weight ratio are as follows: in 100ml medicinal liquid, contain 0.23-0.25g available iodine, 0.13-0.15g hibitane, 0.008-0.012g alkyl phenol polyoxydivinyl ether, the aquatic defoamer of 0.08-0.12g MDZ0,0.06-0.07gTx-10 alkyl acid, all the other are deionized water solvent.
Specifically, component of organization and the weight ratio of sterilization medicinal liquid are as follows: in 100ml medicinal liquid, contain 0.24g available iodine, 0.14g hibitane, 0.01g alkyl phenol polyoxydivinyl ether, the aquatic defoamer of 0.1g MDZ0,0.066gTx-10 alkyl acid, all the other are deionized water solvent.
Take above-mentioned disinfectant liquid as basis, the medical disinfecting cotton ball the present invention relates to is to infiltrate this sterilization medicinal liquid by dry cotton ball to form.
And the preparation method of above-mentioned compound iodine medical disinfecting cotton ball comprises the following steps:
(1) in reaction container, add the deionized water solvent that is less than 100ml amount of solution;
(2) in reaction container, add available iodine, hibitane, alkyl phenol polyoxydivinyl ether, the aquatic defoamer of MDZ0, Tx-10 alkyl acid according to the disinfectant formula of liquid described in claim 1 or 2, stir;
(3) in reaction container, add deionized water solvent, until whole sterilization medicinal liquid reaches 100ml;
(4) the sterilization medicinal liquid that stirs, then packs in finished pot;
(5) according to the ratio of 360-500 cotton balls of 100ml disinfectant immersion profit, dry cotton ball is infiltrated in the sterilization medicinal liquid in finished pot at least 8 hours, then seals finished pot for subsequent use.
Dry cotton ball in described step (5) is infiltrated on in the sterilization medicinal liquid in finished pot, after 10 hours, to seal finished pot for subsequent use.
The present invention both can make sterilized cotton ball, also can make disinfecting cotton swab, even can also make other sterilizing articles, and actual product can determine as required.
Main purpose of the present invention is to reform at the technical of patent No. 00111557.X, by study for a long period of time and test of many times after, obtained new technique of the present invention, reach the object that improves disinfection rate.Because the sterilizing rate of this existing patented technology can reach 99.23% height, therefore its sterilizing rate to improve difficulty very large again, the sterilizing rate of every raising 0.01% all will pass through long-term research and many-sided consideration.The present invention is after the clinic trial of this patented technology is analyzed, detection analysis result in conjunction with professional medical apparatus inspection center is developed, on the basis of existing patented technology, increase alkyl phenol polyoxydivinyl ether and Tx-10 alkyl acid, improve broad-spectrum sterilization effect and strengthen at double sterilization rate, increase the aquatic defoamer of MDZ0, to reach the effect of hydrotropy and raising active component simultaneously.Existing patented technology is because solubilization-aid effect is poor, and its zest is larger, and a lot of sufferers place all cannot be used, such as affected parts such as wound, scald, ulcer.Due to the design of the technology of the present invention, hydrotropy of the present invention and active cost increase greatly, make its range of application more extensive, and the sufferer places such as wound, scald, ulcer can both be used, without any stimulation, so patient is without any pain.And through the test analysis of clinic trial and professional inspection center, disinfection rate of the present invention can reach 100%, than this existing patented technology, has very significant technological progress, can bring higher safety for patient.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described, and embodiments of the present invention include but not limited to the following example.
Embodiment 1
The present invention mainly comprises two parts: the one, and sterilization medicinal liquid, the 2nd, sterilized cotton ball (label), below take sterilize medicinal liquid make corresponding sterilized cotton ball (label) and these two parts are illustrated one by one as example of preparation 100ml.
For improving disinfection rate, the present invention sets about consideration from the formula of sterilization medicinal liquid, and this is also that the work habit of considering medical personnel is difficult to change, and reduces trouble and considers for subsequent applications.The present embodiment adopts and prepares sterilization medicinal liquid as follows: in 100ml medicinal liquid, contain 0.23g available iodine, 0.13g hibitane, 0.008g alkyl phenol polyoxydivinyl ether, the aquatic defoamer of 0.08g MDZ0,0.06gTx-10 alkyl acid, all the other are deionized water solvent.In the time that reality is prepared, first pour a part of deionized water solvent in reaction container, its metering is no more than 100ml, 90-95ml deionized water solvent is first poured in general selection into, then add whole available iodines, hibitane, alkyl phenol polyoxydivinyl ether, the aquatic defoamer of MDZ0 and Tx-10 alkyl acid according to proportioning at normal temperatures, first stir 1-2 minute, when material in question response bucket has a basic degree of mixing, stir again while add deionized water solvent, until the material in reaction container reaches 100ml.On reaction container sidewall, scale is set, operator can judge the amount of solution in reaction container by observing scale.Amount of solution in reaction container reaches after 100ml, continue to stir, until whole medicinal liquid mix homogeneously, then sterilization medicinal liquid is poured in finished pot, deposit for subsequent use.So far, sterilization medicinal liquid has just been prepared.
After sterilization medicinal liquid prepares, should as early as possible dry cotton ball (label) be infiltrated among the sterilization medicinal liquid of finished pot, consider the uniformity of the property of medicine, can in sterilization medicinal liquid, put into 100 dry cotton balls (label) simultaneously, infiltrate and can use after 8 hours, if do not used, can avoid medicinal liquid volatilization by sealing finished pot mouth, cause Disinfection Effect to reduce.After the sterilized cotton ball (label) having infiltrated when early stage uses, can continue to put into dry cotton ball (label) and infiltrate.At follow-up infiltration dry cotton ball (label) before, should first rock finished pot 10 times, make inner sterilization medicinal liquid do certain activity, the medicinal liquid precipitation of bringing to leave standstill finished pot before reducing, the degree of mixing of raising medicinal liquid; Simultaneously, the time of follow-up infiltration dry cotton ball (label) should be slightly longer than previous infiltrating time, generally to increase by 2 hours as good, as: infiltrating for the first time dry cotton ball (label) time is 8 hours, infiltrating so for the second time dry cotton ball (label) time is 10 hours, infiltrating for the third time dry cotton ball (label) is 12 hours, so can provide to greatest extent medicinal liquid to be infiltrated on the effect in dry cotton ball (label), improves the sterilizing rate of sterilized cotton ball (label).But, to consider from the angle of sterilizing rate, the quantity of 100ml disinfectant immersion profit dry cotton ball (label) can not be too many, generally to infiltrate 400 as good.
Embodiment 2
The present embodiment adopts and prepares sterilization medicinal liquid as follows: in 100ml medicinal liquid, contain 0.24g available iodine, 0.14g hibitane, 0.01g alkyl phenol polyoxydivinyl ether, the aquatic defoamer of 0.1g MDZ0,0.066gTx-10 alkyl acid, all the other are deionized water solvent.In the time that reality is prepared, first pour 90ml deionized water solvent in reaction container, then add whole available iodines, hibitane, alkyl phenol polyoxydivinyl ether, the aquatic defoamer of MDZ0 and Tx-10 alkyl acid according to proportioning at normal temperatures, first stir 1 minute, when material in question response bucket has a basic degree of mixing, stir again while add deionized water solvent, until the material in reaction container reaches 100ml.Amount of solution in reaction container reaches after 100ml, continue to stir, until whole medicinal liquid mix homogeneously, then sterilization medicinal liquid is poured in finished pot, deposit for subsequent use.So far, sterilization medicinal liquid has just been prepared.
After sterilization medicinal liquid prepares, should as early as possible 100 dry cotton balls (label) be infiltrated among the sterilization medicinal liquid of finished pot, infiltrate and can use after 12 hours, if do not used, can avoid medicinal liquid volatilization by sealing finished pot mouth, cause Disinfection Effect to reduce.After the sterilized cotton ball (label) having infiltrated when early stage uses, can continue to put into dry cotton ball (label) and infiltrate, 100ml disinfectant immersion profit dry cotton ball (label) 450.At follow-up infiltration dry cotton ball (label) before, first rock finished pot 10 times, make inner sterilization medicinal liquid do certain activity, the medicinal liquid precipitation of bringing to leave standstill finished pot before reducing, the degree of mixing of raising medicinal liquid; Meanwhile, the time of follow-up infiltration dry cotton ball (label) is grown 2 hours than previous infiltrating time.
Embodiment 3
The present embodiment adopts and prepares sterilization medicinal liquid as follows: in 100ml medicinal liquid, contain 0.25g available iodine, 0.15g hibitane, 0.012g alkyl phenol polyoxydivinyl ether, the aquatic defoamer of 0.12g MDZ0,0.07gTx-10 alkyl acid, all the other are deionized water solvent.In the time that reality is prepared, first pour 90ml deionized water solvent in reaction container, then add whole available iodines, hibitane, alkyl phenol polyoxydivinyl ether, the aquatic defoamer of MDZ0 and Tx-10 alkyl acid according to proportioning at normal temperatures, first stir 2 minutes, when material in question response bucket has a basic degree of mixing, stir again while add deionized water solvent, until the material in reaction container reaches 100ml.Amount of solution in reaction container reaches after 100ml, continue to stir, until whole medicinal liquid mix homogeneously, then sterilization medicinal liquid is poured in finished pot, deposit for subsequent use.So far, sterilization medicinal liquid has just been prepared.
After sterilization medicinal liquid prepares, should as early as possible 120 dry cotton balls (label) be infiltrated among the sterilization medicinal liquid of finished pot, infiltrate and can use after 8 hours, if do not used, can avoid medicinal liquid volatilization by sealing finished pot mouth, cause Disinfection Effect to reduce.After the sterilized cotton ball (label) having infiltrated when early stage uses, can continue to put into dry cotton ball (label) and infiltrate, 100ml disinfectant immersion profit dry cotton ball (label) 500.At follow-up infiltration dry cotton ball (label) before, first rock finished pot 10 times, make inner sterilization medicinal liquid do certain activity, the medicinal liquid precipitation of bringing to leave standstill finished pot before reducing, the degree of mixing of raising medicinal liquid; Meanwhile, the time of follow-up infiltration dry cotton ball (label) is grown 3 hours than previous infiltrating time.
Detect and analyze through the specialty of medical apparatus and instruments inspection center of Sichuan Province, the sterilized cotton ball sterilizing rate that above-mentioned three embodiment obtain is as following table:
| Sequence number | To the sterilizing rate of staphylococcus aureus | To colibacillary sterilizing rate | To the sterilizing rate of Candida albicans |
| Embodiment 1 | 99.8%～99.93% | 99.9%～99.98% | 99.87%～99.95% |
| Embodiment 2 | 99.90%～100% | 99.9%～100% | 99.90～99.99% |
| Embodiment 3 | 99.99%～100% | 99.99%～100% | 99.99% |
Can find out from above-mentioned testing result, in disinfection rate of the present invention, the highest sterilizing rate to single pathogenic bacteria can reach 100%, and from overall sterilizing rate, also can be stabilized to 99.99%, than existing patented technology and other routine disinfection cotton balls, sterilizing rate has reached the peak of existing medical circle sterilization, and technological progress is very huge.
Above-described embodiment is only the preferred embodiments of the present invention, and not limiting the scope of the invention adopts design principle of the present invention in every case, and carries out non-creativeness work on this basis and the variation made, within all should belonging to protection scope of the present invention.
Claims (5)
1. a sterilization medicinal liquid, it is characterized in that, its component of organization and weight ratio are as follows: in 100ml medicinal liquid, contain 0.23-0.25g available iodine, 0.13-0.15g hibitane, 0.008-0.012g alkyl phenol polyoxydivinyl ether, the aquatic defoamer of 0.08-0.12g MDZ0,0.06-0.07gTx-10 alkyl acid, all the other are deionized water solvent.
2. a kind of sterilization medicinal liquid according to claim 1, it is characterized in that, its component of organization and weight ratio are as follows: in 100ml medicinal liquid, contain 0.24g available iodine, 0.14g hibitane, 0.01g alkyl phenol polyoxydivinyl ether, the aquatic defoamer of 0.1g MDZ0,0.066gTx-10 alkyl acid, all the other are deionized water solvent.
3. the compound iodine medical disinfecting cotton ball of being made up of sterilization medicinal liquid, is characterized in that, is made up of the sterilization medicinal liquid described in dry cotton ball infiltration claim 1 or 2.
4. the preparation method of compound iodine medical disinfecting cotton ball, is characterized in that, comprises the following steps:
(1) in reaction container, add the deionized water solvent that is less than 100ml amount of solution;
(2) in reaction container, add available iodine, hibitane, alkyl phenol polyoxydivinyl ether, the aquatic defoamer of MDZ0, Tx-10 alkyl acid according to the disinfectant formula of liquid described in claim 1 or 2, stir;
(3) in reaction container, add deionized water solvent, until whole sterilization medicinal liquid reaches 100ml;
(4) the sterilization medicinal liquid that stirs, then packs in finished pot;
(5) according to the ratio of 360-500 cotton balls of 100ml disinfectant immersion profit, dry cotton ball is infiltrated in the sterilization medicinal liquid in finished pot at least 8 hours, then seals finished pot for subsequent use.
5. the preparation method of compound iodine medical disinfecting cotton ball according to claim 4, is characterized in that, in described step (5), dry cotton ball is infiltrated on in the sterilization medicinal liquid in finished pot, after 12 hours, to seal finished pot for subsequent use.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310658586.6A CN103816179A (en) | 2013-12-09 | 2013-12-09 | Disinfecting liquid, medical compound iodine sterile cotton ball prepared from disinfecting liquid, and corresponding preparation method |
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| CN201310658586.6A CN103816179A (en) | 2013-12-09 | 2013-12-09 | Disinfecting liquid, medical compound iodine sterile cotton ball prepared from disinfecting liquid, and corresponding preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104523748A (en) * | 2015-01-05 | 2015-04-22 | 四川悦康源通药业有限公司 | Compound iodine disinfectant and preparation method and application thereof |
| CN106389466A (en) * | 2016-11-15 | 2017-02-15 | 贵州碘雅医疗器械有限公司 | 98-compound iodine disinfection solution and preparation method thereof |
| CN112933161A (en) * | 2021-02-04 | 2021-06-11 | 贵州碘雅医疗器械有限公司 | Composite iodophor disinfectant |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1271566A (en) * | 2000-01-27 | 2000-11-01 | 杭州杨驰旅游用品有限公司 | Medical disinfecting cotton ball and its preparing method |
| CN102258803A (en) * | 2011-07-20 | 2011-11-30 | 王旋旋 | Long-acting medical skin sterilization cotton ball |
-
2013
- 2013-12-09 CN CN201310658586.6A patent/CN103816179A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1271566A (en) * | 2000-01-27 | 2000-11-01 | 杭州杨驰旅游用品有限公司 | Medical disinfecting cotton ball and its preparing method |
| CN102258803A (en) * | 2011-07-20 | 2011-11-30 | 王旋旋 | Long-acting medical skin sterilization cotton ball |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104523748A (en) * | 2015-01-05 | 2015-04-22 | 四川悦康源通药业有限公司 | Compound iodine disinfectant and preparation method and application thereof |
| CN106389466A (en) * | 2016-11-15 | 2017-02-15 | 贵州碘雅医疗器械有限公司 | 98-compound iodine disinfection solution and preparation method thereof |
| CN112933161A (en) * | 2021-02-04 | 2021-06-11 | 贵州碘雅医疗器械有限公司 | Composite iodophor disinfectant |
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Effective date of registration: 20141124 Address after: 102 room 310000, middle building, 21 Chuk Yuen, Chengxiang street, Xiaoshan District, Zhejiang, Hangzhou Applicant after: Fan Jiansheng Address before: 102 room 310000, middle building, 21 Chuk Yuen, Chengxiang street, Xiaoshan District, Zhejiang, Hangzhou Applicant before: Fan Jiansheng Applicant before: Zhang Xueming |
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