CN103784820B - For treating Chinese medicine formula and the Chinese medicinal capsule of cardiovascular stasis coronary heart disease - Google Patents

For treating Chinese medicine formula and the Chinese medicinal capsule of cardiovascular stasis coronary heart disease Download PDF

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CN103784820B
CN103784820B CN201410059640.XA CN201410059640A CN103784820B CN 103784820 B CN103784820 B CN 103784820B CN 201410059640 A CN201410059640 A CN 201410059640A CN 103784820 B CN103784820 B CN 103784820B
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radix
chinese medicine
heart disease
coronary heart
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CN103784820A (en
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罗金秀
谢璐漾
谢璐岭
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Luo Jinxiu
Xie Luling
Xie Luyang
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Abstract

The present invention relates to a kind of Chinese medicine formula for treating cardiovascular stasis coronary heart disease, it is made up of Radix Salviae Miltiorrhizae, Folium Ginkgo, Rhizoma Corydalis, Rhizoma Chuanxiong, Fructus Hordei Germinatus, Cortex Moutan, Fructus Crataegi, Radix Ginseng, Semen Persicae, Stigma Croci, Radix Paeoniae Rubra, Caulis Spatholobi, Fructus Aurantii, Pericarpium Citri Reticulatae, Herba Artemisiae Anomalae, Radix Glycyrrhizae, Radix Angelicae Sinensis, the Radix Rehmanniae, Radix Bupleuri, Lignum Dalbergiae Odoriferae, the Radix Paeoniae Alba, Bulbus Allii Macrostemonis, Radix Platycodonis, Medulla Tetrapanacis, Oletum Trogopterori, Ramulus Cinnamomi, Rhizoma Polygonati Odorati, Radix Notoginseng, Styrax and Borneolum Syntheticum according to the mass fraction.Having the effect such as blood circulation promoting and blood stasis dispelling, coronary circulation-promoting pain-relieving, cure rate is more than 90%.Meanwhile, this Chinese medicine formula can be alleviated or cure and can be induced the hypertension of cardiovascular stasis coronary heart disease, hyperlipidemia.

Description

For treating Chinese medicine formula and the Chinese medicinal capsule of cardiovascular stasis coronary heart disease
Technical field
The present invention relates to treat the Chinese patent medicine of coronary heart disease, particularly for the Chinese medicine formula for the treatment of cardiovascular stasis coronary heart disease.In addition the invention still further relates to Chinese medicinal capsule, the Chinese medicinal pill using this Chinese medicine formula to make.It finds particular application to cardiovascular stasis coronary heart disease angina pectoris, myocardial infarction and heart failure etc. are also had to certain curative effect.
Background technology
Although coronary heart disease is all coronary artery pathological changes, but according to the difference of clinical manifestation, can be divided into angina pectoris, myocardial infarction, heart failure and arrhythmia etc., wherein angina pectoris is most commonly seen.Before middle medical drugs treatment coronary heart disease, first wanting typing dialectical, different dialectical needs use different pharmaceutical combination.Stagnation of heart-blood is a kind of common type of angina pectoris.Existing patent documentation discloses the Chinese patent medicine of multiple treatment cardiovascular stasis coronary heart disease (angina pectoris).
96115634.1 relate to a kind of Chinese medicine oral liquid treating coronary heart diseases and angina pectoris.This case shows, Radix Salviae Miltiorrhizae and Cortex Moutan are conducive to the thoracic obstruction that treatment stagnation of heart-blood causes.
99102847.3 relate to a kind of rhodiola rosea injection treating angina pectoris, and this case extracts the effective ingredient for the treatment of angina pectoris from Radix Rhodiolae, and the angina pectoris that stagnation of heart-blood is caused by this injection has obvious curative effects.
02146248.8(1186069C) relate to one and there is blood circulation promoting and blood stasis dispelling, the Chinese medicine preparation of regulating QI to relieve pain effect, in this case, Radix Bupleuri can dispersing the stagnated live-QI to relieve the stagnation of QI, Fructus Aurantii can circulation of qi promoting go stagnant.
200610173375.3(100546639C) disclosing a kind of Chinese herbal medicine pill treating coronary heart disease, this case illustrates Borneolum Syntheticum effect in treatment heart blood silt.
Treatment palpitation and uneasiness, the Chinese medicine of sensation of oppression over the chest with shortness of breath of 200710133059.8 disclose the Radix Rehmanniae, Radix Curcumae and Semen Persicae and are conducive to alleviating stagnation of heart-blood.
200910023341.X or 200910023338.8 all discloses the medicine pill for the treatment of coronary heart diseases and angina pectoris, shows that a small amount of Borneolum Syntheticum can have effect in document.
200910064559.X relates to a kind of thrombolysis decoction treating cardiovascular disease, and in this case, the effect in treatment type of obstruction of heart-blood cardiovascular disease of Radix Ginseng, Fructus Trichosanthis and Radix Curcumae can include term of reference in.
200910086871.9 the scheme of Chinese medicine formula for the treatment of angina pectoris simple, do not repeat.
201110273370.9(102302550B) disclose the medicine for the treatment of coronary heart disease, comprising: Folium Ginkgo 20 30 parts, Radix Salviae Miltiorrhizae 15 25 parts, Rhizoma Chuanxiong 10 15 parts, 10 15 parts of Flos Carthami, 10 15 parts of Radix Notoginseng.This application is with Folium Ginkgo as monarch drug.
201110267629.9(102302741B) disclose a kind of Chinese medicinal preparation method treating the type of obstruction of heart-blood thoracic obstruction, the component of this Chinese medicine is more, wherein, the effect in treatment stagnation of heart-blood such as Herba Artemisiae Anomalae, Caulis Spatholobi, Bulbus Allii Macrostemonis and Rhizoma Cyperi can be as the prior art of the application.In addition it is also possible to see the Chinese medicinal preparation method of the treatment type of obstruction of heart-blood cardiopalmus of 201110267624.6.
201210200040.1 relate to Flos Carthami Chinese medicine decoction and the preparation method treating cardiopalmus, and it includes Flos Carthami 100-140 part, Radix Salviae Miltiorrhizae 200-280 part, Ganoderma 150-210 part, Radix Paeoniae Rubra 150-210 part, Rhizoma Chuanxiong 100-140 part, Rhizoma Corydalis 150-210 part.Type of obstruction of heart-blood cardiopalmus belongs to a kind of performance of cardiovascular disease, can be as reference.Additionally, the treatment stagnation of heart-blood of 201110278139.9 causes the Chinese medicine formula of cardiopalmus, also similar with this application.
Except above-mentioned patent documentation, the medicine such as yufeng ningxin tablets, yufeng ningxin pian, Ginkgo oral liquid and GUANXINNING ZHUSHEYE can treat the angina pectoris that stagnation of heart-blood causes to a certain extent, but similar to existing patented technology, and its cure rate and curative effect have much room for improvement.
Summary of the invention
For solving problem of the prior art, the present invention provides a kind of Chinese medicine formula treating the angina pectoris that stagnation of heart-blood causes.This Chinese medicine formula, according to components such as the anginal feature of cardiovascular stasis coronary heart disease, reasonable compatibility Folium Ginkgo, Radix Ginseng and Oletum Trogopteroris, reaches without adverse affects to treat angina pectoris.
nullA kind of Chinese medicine formula for treating cardiovascular stasis coronary heart disease,It is characterized in that,According to the mass fraction,Consist of the following composition: Radix Salviae Miltiorrhizae 200 ~ 210 parts、Folium Ginkgo 180 ~ 210 parts、Rhizoma Corydalis 135 ~ 145 parts、Rhizoma Chuanxiong 135 ~ 145 parts、120 ~ 129 parts of Fructus Hordei Germinatus、Cortex Moutan 120 ~ 129 parts、Fructus Crataegi 120 ~ 129 parts、Radix Ginseng 105 ~ 110 parts、105 ~ 110 parts of Semen Persicae、Stigma Croci 105 ~ 110 parts、Radix Paeoniae Rubra 105 ~ 110 parts、Caulis Spatholobi 105 ~ 110 parts、Fructus Aurantii 90 ~ 110 parts、Pericarpium Citri Reticulatae 86 ~ 110 parts、Herba Artemisiae Anomalae 86 ~ 89 parts、86 ~ 89 parts of Radix Glycyrrhizae、Radix Angelicae Sinensis 86 ~ 89 parts、86 ~ 89 parts of the Radix Rehmanniae、Radix Bupleuri 86 ~ 89 parts、Lignum Dalbergiae Odoriferae 80 ~ 110 parts、The Radix Paeoniae Alba 80 ~ 90 parts、Bulbus Allii Macrostemonis 80 ~ 85 parts、Radix Platycodonis 80 ~ 85 parts、Medulla Tetrapanacis 55 ~ 70 parts、Oletum Trogopterori 58 ~ 60 parts、Ramulus Cinnamomi 55 ~ 60 parts、Rhizoma Polygonati Odorati 55 ~ 60 parts、Radix Notoginseng 55 ~ 60 parts、Styrax 40 ~ 50 parts、Borneolum Syntheticum 8 ~ 10 parts.
As preferably: Radix Salviae Miltiorrhizae 210 parts, Folium Ginkgo 180 parts, Rhizoma Corydalis 145 parts, Rhizoma Chuanxiong 145 parts, 129 parts of Fructus Hordei Germinatus, Cortex Moutan 129 parts, Fructus Crataegi 129 parts, Radix Ginseng 110 parts, 110 parts of Semen Persicae, Stigma Croci 110 parts, Radix Paeoniae Rubra 110 parts, Caulis Spatholobi 110 parts, Fructus Aurantii 90 parts, Pericarpium Citri Reticulatae 86 parts, Herba Artemisiae Anomalae 86 parts, 86 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 86 parts, 86 parts of the Radix Rehmanniae, Radix Bupleuri 86 parts, Lignum Dalbergiae Odoriferae 80 parts, the Radix Paeoniae Alba 80 parts, Bulbus Allii Macrostemonis 80 parts, Radix Platycodonis 80 parts, Medulla Tetrapanacis 70 parts, Oletum Trogopterori 60 parts, Ramulus Cinnamomi 60 parts, Rhizoma Polygonati Odorati 60 parts, Radix Notoginseng 60 parts, Styrax 50 parts, Borneolum Syntheticum 8 parts.
As preferably: Radix Salviae Miltiorrhizae 200 parts, Folium Ginkgo 210 parts, Rhizoma Corydalis 135 parts, Rhizoma Chuanxiong 145 parts, 120 parts of Fructus Hordei Germinatus, Cortex Moutan 120 parts, Fructus Crataegi 120 parts, Radix Ginseng 105 parts, 105 parts of Semen Persicae, Stigma Croci 105 parts, Radix Paeoniae Rubra 105 parts, Caulis Spatholobi 105, Fructus Aurantii 110 parts, Pericarpium Citri Reticulatae 110 parts, Herba Artemisiae Anomalae 89 parts, 89 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 89 parts, 89 parts of the Radix Rehmanniae, Radix Bupleuri 89 parts, Lignum Dalbergiae Odoriferae 110 parts, the Radix Paeoniae Alba 90 parts, Bulbus Allii Macrostemonis 85 parts, Radix Platycodonis 85 parts, Medulla Tetrapanacis 55 parts, Oletum Trogopterori 58 parts, Ramulus Cinnamomi 55 parts, Rhizoma Polygonati Odorati 55 parts, Radix Notoginseng 55 parts, Styrax 40 parts, Borneolum Syntheticum 10 parts.
As preferably: Radix Salviae Miltiorrhizae 205 parts, Folium Ginkgo 200 parts, Rhizoma Corydalis 140 parts, Rhizoma Chuanxiong 138 parts, 125 parts of Fructus Hordei Germinatus, Cortex Moutan 125 parts, Fructus Crataegi 125 parts, Radix Ginseng 100 parts, 100 parts of Semen Persicae, Stigma Croci 100 parts, Radix Paeoniae Rubra 100 parts, Caulis Spatholobi 100 parts, Fructus Aurantii 100 parts, Pericarpium Citri Reticulatae 100 parts, Herba Artemisiae Anomalae 88 parts, 86 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 86 parts, 88 parts of the Radix Rehmanniae, Radix Bupleuri 86 parts, Lignum Dalbergiae Odoriferae 90 parts, the Radix Paeoniae Alba 85 parts, Bulbus Allii Macrostemonis 82 parts, Radix Platycodonis 82 parts, Medulla Tetrapanacis 65 parts, Oletum Trogopterori 59 parts, Ramulus Cinnamomi 58 parts, Rhizoma Polygonati Odorati 58 parts, Radix Notoginseng 58 parts, Styrax 45 parts, Borneolum Syntheticum 9 parts.
As preferably: Radix Salviae Miltiorrhizae 200 parts, Folium Ginkgo 200 parts, Rhizoma Corydalis 140 parts, Rhizoma Chuanxiong 140 parts, 125 parts of Fructus Hordei Germinatus, Cortex Moutan 125 parts, Fructus Crataegi 125 parts, Radix Ginseng 100 parts, 100 parts of Semen Persicae, Stigma Croci 100 parts, Radix Paeoniae Rubra 100 parts, Caulis Spatholobi 100 parts, Fructus Aurantii 100 parts, Pericarpium Citri Reticulatae 100 parts, Herba Artemisiae Anomalae 90 parts, 90 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 90 parts, 90 parts of the Radix Rehmanniae, Radix Bupleuri 90 parts, Lignum Dalbergiae Odoriferae 100 parts, the Radix Paeoniae Alba 80 parts, Bulbus Allii Macrostemonis 80 parts, Radix Platycodonis 80 parts, Medulla Tetrapanacis 60 parts, Oletum Trogopterori 60 parts, Ramulus Cinnamomi 60 parts, Rhizoma Polygonati Odorati 60 parts, Radix Notoginseng 60 parts, Styrax 40 parts, Borneolum Syntheticum 10 parts.
A kind of Chinese medicinal capsule for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula.
A kind of Chinese medicinal pill for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and Mel, mass ratio is 1:0.5 ~ 1.5.
A kind of Chinese medicine preparation for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and solvent.
In this Chinese medicine preparation, described solvent is rice wine, and by mass percentage, it is 1:8 ~ 10 with the proportioning of Chinese medicine formula.
In this Chinese medicine preparation, described solvent is yellow wine, and by mass percentage, it is 1:5 ~ 10 with the proportioning of Chinese medicine formula.
In this Chinese medicine preparation, described solvent is ethanol, and by mass percentage, it is 1:1 ~ 6 with the proportioning of Chinese medicine formula.
The Chinese medicine formula of this treatment cardiovascular stasis coronary heart disease of the present invention, has the effect such as blood circulation promoting and blood stasis dispelling, coronary circulation-promoting pain-relieving, cures mainly stagnation of heart-blood, and cure rate is more than 90%.This Chinese medicine formula, on the basis of considering each constituent content, optimizes the proportioning of Radix Ginseng and Oletum Trogopterori, improves the effect of blood circulation promoting and blood stasis dispelling.Although this Chinese medicine formula is formed by several kinds of Chinese medicinal materials compatibility, but it cures mainly clearly, has no side effect.Meanwhile, this Chinese medicine formula can be alleviated or cure and can be induced the hypertension of cardiovascular stasis coronary heart disease, hyperlipidemia.
Detailed description of the invention
Some provided for the apparent explanation present invention, first summary prior art treat anginal scheme.Background section has explained, no longer describes in detail.Patent, patent application and other documents that the application directly quotes, includes this case in as reference, and other do not make the part expressed, with reference to known technology.
Existing patent documentation discloses multiple document for treating coronary heart disease.
201110048251.3(102119971B) relating to a kind of Chinese medicine treating coronary heart disease, it includes Ramulus Persicae 1-3 part, Herba Potentillae Discoloris 1-3 part, Moschus 0.5-1 part, Pemisetum flaccidum Griseb. 2-5 part, Herba Plantaginis 1-3 part and anistree 0.5-1 part.Coronary heart disease differentiation of symptoms and signs for classification of syndrome is complicated, and same component is difficult to treat all types of coronary heart disease.
201310342311.1 relate to a kind of medicine treating coronary heart diseases and angina pectoris, the white 20-60g of Flos Carthami 20-60g, a round bamboo basket, Radix Platycodonis 10-30g, Rhizoma Acori Graminei 5-15g, Ramulus Cinnamomi 10-30g, Rhizoma Corydalis 10-20g, Fructus Trichosanthis 30-100g, Herba Potentillae Discoloris 10-30g, Moschus 10-30g, Radix Aucklandiae 10-30g, Semen Platycladi 20-60g, Caulis Spatholobi 10-30g, 10-30g Radix Ophiopogonis, Herba Plantaginis 20-60g, Radix Puerariae 10-30g, Rhizoma Curculiginis 10-20g, Oletum Trogopterori 10-30g, Semen Persicae 10-20g, Radix Polygalae 20-60g, Semen Lepidii (Semen Descurainiae) 10-30g, big gun first 5-15g, Fructus Toosendan 5-15g, Rhizoma Zingiberis 5-15g, Radix Glycyrrhizae Preparata 10-30g.
201210541518.7 relate to a kind of Chinese medicine formula for angina pectoris, the Chinese medicine formula crude drug of following weight proportion it is prepared from: Rhizoma Corydalis 220-260 part, Moschus 4-12 part, Styrax 4-12 part, Rhizoma Chuanxiong 100-140 part, Radix Ginseng 100-140 part, Borneolum Syntheticum 6-18 part.Borneolum Syntheticum GUIXIN, liver, can control blood stasis.Borneolum Syntheticum is poisonous, should limit its intake.
201110453345.9 disclose a kind of Chinese medicine formula treating angina pectoris, and it is by Radix Codonopsis, the Radix Astragali, Fructus Mori, Rhizoma Chuanxiong, Radix Curcumae, Oletum Trogopterori, Flos Rosae Rugosae, Semen Litchi and Lignum Aquilariae Resinatum.Radix Codonopsis, the Radix Astragali, Fructus Mori, Rhizoma Chuanxiong, Radix Curcumae, Oletum Trogopterori are the good medicine treating qi stagnation and blood stasis type coronary heart disease.
201110174824.7 relate to a kind of medicine treating coronary heart disease, it optimizes the proportioning of American ginseng total saponins and tetrahydropalmatine.
201110155727.3 relate to the Chinese medicine treating coronary heart disease, and it includes Radix Rehmanniae Preparata 25~50 parts, Fructus Corni 10~25 parts, Herba Cistanches 15~30 parts, gun additioner 5~20 parts, Radix Ginseng 5~15 parts, Radix Ophiopogonis 15~25 parts, Fructus Schisandrae Chinensis 2.5~10 parts, Ramulus Cinnamomi 5~15 parts, Radix Glycyrrhizae 5~10 parts, Radix Angelicae Sinensis 10~25 parts, the Radix Astragali 15~50 parts, Radix Salviae Miltiorrhizae 15~50 parts, Lignum Santali Albi 1.5~5 parts, Fructus Amomi 5~10 parts, Rhizoma Chuanxiong 5~15 parts, Fructus Crataegi 10~20 parts, Flos Lonicerae 15~25 parts, Radix Scrophulariae 15~25 parts, the Radix Rehmanniae 15~50 parts.This case treats all types of coronary heart disease with same component.
Although, ancient Chinese medicine has the saying of " Radix Ginseng fear Oletum Trogopterori ", but modern TCM research shows, under rational proportioning or rational solvent action, people participates in Oletum Trogopterori compatibility can treat multiple disease.Such as, " Radix Ginseng, the Oletum Trogopterori compatibility experimentation to A549 human lung adenocarcinoma cell line effect " (Traditional Chinese Medicinal College of Liaoning. Wang Jin), the chemical substance basic research of Oletum Trogopterori " Radix Ginseng fear " (time treasure's traditional Chinese medical science traditional Chinese medicines. a howl ring D etc.), " Oletum Trogopterori " mutual restraint between two drugs " simple analysis joined by Radix Ginseng " Liu Yuchun etc., and " Radix Ginseng, the modern study progress of Oletum Trogopterori compatibility " (China's Chinese medicine magazine. Li Lian etc.) all this has been made careful research.Certainly, people participates in the proportion compatibility of Oletum Trogopterori and has to take into account that the impact of other compositions, such as Radix Salviae Miltiorrhizae, the Radix Astragali etc. in prescription.Existing patent documentation also discloses that the patent formula of some ginseng compatibility's Oletum Trogopteroris.In view of other components in prescription, in this application, Radix Ginseng: Oletum Trogopterori is 120 ~ 125:74 ~ 76.
01131203.3(1124153B) disclose a kind of medicinal composition for restoring cardiac collaterals, be used for treating angina pectoris.It includes the Radix Ginseng of Rational Dosage, Radix Codonopsis, Radix Pseudostellariae, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Rhizoma Dioscoreae one of which or several clinically;Hirudo, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Flos Carthami, Radix Paeoniae Rubra, Lignum Dalbergiae Odoriferae, Radix Notoginseng, Radix Curcumae, Semen Persicae, Rhizoma Corydalis, Eupolyphaga Seu Steleophaga, Olibanum, Sanguis Draxonis, Myrrha, Caulis Spatholobi, Lignum Aquilariae Resinatum, Rhizoma Curcumae, Rhizoma Sparganii, Herba Leonuri, Oletum Trogopterori, Radix Achyranthis Bidentatae, Fructus Trichosanthis, the Rhizoma Pinelliae, Bulbus Allii Macrostemonis, Semen Armeniacae Amarum, Fructus Aurantii, Fructus Aurantii Immaturus, Lignum Santali Albi, Rhizoma Cyperi, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Radix Platycodonis, Rhizoma Corydalis, Radix Polygoni Multiflori, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, the Radix Paeoniae Alba, Radix Ophiopogonis, Rhizoma Polygonati, Borneolum Syntheticum, Rhizoma Acori Graminei, Semen Ziziphi Spinosae, Radix Polygalae, succinum, Herba Asari, Radix Aconiti Lateralis Preparata, Ramulus Cinnamomi, Herba Epimedii, Fructus Schisandrae Chinensis, Fructus Crataegi, Radix Puerariae, Poria, the Radix Angelicae Dahuricae, Radix Bupleuri, Pheretima, Rhizoma Gastrodiae one of which or several and Scorpio, Periostracum Cicadae, Scolopendra one of which or several combination preparations.The specific embodiments of this case is more, and each component all has an effect of blood circulation promoting and blood stasis dispelling, but is whether to be used equally to treat angina pectoris, needs empirical research.
200810127216.9 relate to a kind of medicated wine treating coronary heart disease, and it includes Radix Salviae Miltiorrhizae, Rhizoma Corydalis, Fructus Crataegi, Radix Ginseng, Cortex Cinnamomi, Radix Angelicae Sinensis, Cordyceps, Flos Carthami, Rhizoma Chuanxiong, Vascular aurantii, Herba Saussureae Involueratae, Radix Notoginseng, Oletum Trogopterori and sticky rice wine.In this case, people participates in Oletum Trogopterori equivalent.
The 200810127966.6 a kind of methods disclosing treating swine coronary diseases with traditional Chinese medicines, Radix Salviae Miltiorrhizae, Rhizoma Corydalis, Fructus Crataegi, Radix Ginseng, Cortex Cinnamomi, Radix Angelicae Sinensis, Cordyceps, Flos Carthami, Rhizoma Chuanxiong, Vascular aurantii, Herba Saussureae Involueratae, Radix Notoginseng, Oletum Trogopterori.In this case, Radix Ginseng is less than Oletum Trogopterori.It is said that this component may be used for treating swine coronary diseases.
200910234765.0 relate to a kind of Chinese medicine treating swine coronary diseases, are made up of Semen Cassiae 40 grams, Radix Salviae Miltiorrhizae 50 grams, the Rhizoma Anemarrhenae 20 grams, Fructus Crataegi 30 grams, Radix Ginseng 10 grams, Radix Paeoniae Rubra 20 grams, Radix Angelicae Sinensis 20 grams, Cordyceps 20 grams, 20 grams of Flos Carthami, Rhizoma Chuanxiong 20 grams, 20 grams of Semen Persicae, Herba Saussureae Involueratae 20 grams, Herba Leonuri 40 grams, Radix Notoginseng 50 grams, Oletum Trogopterori 20 grams.In this case, the quantity of Radix Ginseng is less than Oletum Trogopterori.
200910019636.X relates to a kind of Chinese medicine formula treating palace blood and preparation method thereof, and it includes Radix Ginseng, the Radix Astragali, Cortex Phellodendri, Carapax et Plastrum Testudinis, Radix Scutellariae, Fructus Rosae Laevigatae, the Radix Paeoniae Alba, Radix Polygoni Multiflori Preparata, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, Rhizoma Cyperi, gun ginger, Radix Rehmanniae Preparata, Chinese mugwort charcoal, the Rhizoma Atractylodis Macrocephalae and cyrtomium rhizome charcoal.Radix Ginseng, the Radix Astragali, Radix Glycyrrhizae and Radix Angelicae Sinensis etc. are the good medicine for the treatment of qi depression to blood stasis.
201010263713.9 disclose a kind of medicine treating coronary heart disease and preparation method thereof, and in this case, people participates in the proportioning of Oletum Trogopterori is 1 ~ 20:1 ~ 20.Oletum Trogopterori contains the composition reducing Radix Ginseng effect, and people participates in Oletum Trogopterori and reduces effect in big ratio range compatibility, possibility or have side effects.
Treat menorrheal Chinese medicine formula, be made up of each raw material of following weight portion: Radix Ginseng 20~40 parts, the Radix Astragali 20~40 parts, the Rhizoma Atractylodis Macrocephalae 10~20 parts, Radix Glycyrrhizae Preparata 3~9 parts, Rhizoma Cimicifugae 3~9 parts, Colla Corii Asini 5~15 parts, the Radix Rehmanniae 10~20 parts, Pollen Typhae 8~15 parts, Herba Leonuri 10~30 parts, Oletum Trogopterori 5~15 parts, Radix Notoginseng 3~9 parts, Radix Rubiae 3~9 parts for 201210537333.9 1 kinds.In this Chinese medicinal components, Radix Ginseng is about two to four times of Oletum Trogopterori.
201010288583.4 disclose a kind of Chinese medicine preparation treating femur head necrosis, including: Radix Polygoni Multiflori Preparata 10-20 part, Radix Rehmanniae Preparata 10-20 part, Radix Angelicae Sinensis 10-15 part, Colla Corii Asini 10-15 part, Radix Paeoniae Alba 10-20 part, Radix Ginseng 5-10 part, Radix Codonopsis 10-20 part, Radix Pseudostellariae 10-20 part, Radix Astragali 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Rhizoma Dioscoreae 10-20 part, Olibanum 10-15 part, Myrrha 10-15 part, Rhizoma Corydalis 10-15 part, Oletum Trogopterori 10-15 part.This case treats femur head necrosis in the way of blood circulation promoting and blood stasis dispelling, nourishing the liver and kidney.
201310468625.6 formula disclosing a kind of Radix Ginseng activating blood circulation to dissipate blood stasis wine, including Radix Ginseng 20-35 part, Rhizoma Corydalis 10-30 part, Concha Arcae 10-30 part, Radix Rubiae 10-30 part, Thallus Laminariae (Thallus Eckloniae) 10-30 part, Semen Raphani 10-30 part, wide art 10-30 part, Exocarpium Citri Rubrum 10-30 part, Oletum Trogopterori 10-30 part, Herba Lycopi's 10-30 part, Rhizoma Sparganii 10-30 part, Lignum Sappan 10-30 part, Hirudo 10-30 part, Radix Achyranthis Bidentatae 10-30 part, Rhizoma Curcumae Longae 10-30 part, Caulis Hederae Sinensis 10-30 part, Flos Rosae Chinensis 10-30 part.In this case, the content of Radix Ginseng is slightly larger than Oletum Trogopterori.
nullThis Chinese medicine formula for treating cardiovascular stasis coronary heart disease of the present invention,According to the mass fraction,Consist of the following composition: Radix Salviae Miltiorrhizae 200 ~ 210 parts、Folium Ginkgo 180 ~ 210 parts、Rhizoma Corydalis 135 ~ 145 parts、Rhizoma Chuanxiong 135 ~ 145 parts、120 ~ 129 parts of Fructus Hordei Germinatus、Cortex Moutan 120 ~ 129 parts、Fructus Crataegi 120 ~ 129 parts、Radix Ginseng 105 ~ 110 parts、105 ~ 110 parts of Semen Persicae、Stigma Croci 105 ~ 110 parts、Radix Paeoniae Rubra 105 ~ 110 parts、Caulis Spatholobi 105 ~ 110 parts、Fructus Aurantii 90 ~ 110 parts、Pericarpium Citri Reticulatae 86 ~ 110 parts、Herba Artemisiae Anomalae 86 ~ 89 parts、86 ~ 89 parts of Radix Glycyrrhizae、Radix Angelicae Sinensis 86 ~ 89 parts、86 ~ 89 parts of the Radix Rehmanniae、Radix Bupleuri 86 ~ 89 parts、Lignum Dalbergiae Odoriferae 80 ~ 110 parts、The Radix Paeoniae Alba 80 ~ 90 parts、Bulbus Allii Macrostemonis 80 ~ 85 parts、Radix Platycodonis 80 ~ 85 parts、Medulla Tetrapanacis 55 ~ 70 parts、Oletum Trogopterori 58 ~ 60 parts、Ramulus Cinnamomi 55 ~ 60 parts、Rhizoma Polygonati Odorati 55 ~ 60 parts、Radix Notoginseng 55 ~ 60 parts、Styrax 40 ~ 50 parts、Borneolum Syntheticum 8 ~ 10 parts.
Pharmacology: Radix Salviae Miltiorrhizae can blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia.Folium Ginkgo promoting blood circulation and stopping pain, is used for treating hyperlipidemia, hypertension, angina pectoris.Rhizoma Corydalis can be invigorated blood circulation, circulation of qi promoting, pain relieving.Rhizoma Chuanxiong can blood-activating and qi-promoting, wind-expelling pain-stopping.Fructus Hordei Germinatus joins Radix Bupleuri etc., stagnant by the treating the liver stagnation of QI, Ben Fangzhong, it is preferred to use Fructus Hordei Germinatus (parched).Cortex Moutan GUIXIN, liver, kidney channel, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Fructus Crataegi can be passed through QI and blood, has the merit of promoting blood circulation to disperse blood clots and relieves pain.Radix Ginseng can strongly invigorating primordial QI, under certain condition can compatibility Oletum Trogopterori.Semen Persicae enters conscience blood system, is apt to let out stasis, and blood stasis dispelling power is strong, also known as stasis-breaking drug, for treating the common medicine of multiple stagnation of blood stasis disease.Stigma Croci can removing blood stasis, promoting the circulation of blood and blood, tune blood, strength is better than Flos Carthami.Radix Paeoniae Rubra returns Liver Channel, can clearing away heat and cooling blood, eliminating stasis to stop pain, Radix Bupleuri, Cortex Moutan etc. can be joined medicinal.Caulis Spatholobi returns liver, kidney channel, can blood circulation promoting and enriching, menstruction regulating and pain relieving, Chang Peiwu benefiting QI for activating blood circulation dredging collateral medicine.Fructus Aurantii nature and flavor, Gui Jing, function are same with Fructus Aurantii Immaturus, but effect relatively relaxes.Pericarpium Citri Reticulatae have pungent row temperature lead to, have promoting the circulation of QI to relieve pain, spleen invigorating and in merit.Herba Artemisiae Anomalae is good at row and is dissipated, and can stimulate the menstrual flow by removing blood stasis, and eliminating stasis to stop pain can join Semen Persicae, Radix Angelicae Sinensis, Rhizoma Chuanxiong etc..Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription, and invigorating the spleen and replenishing QI medicine compatibilities such as Radix Ginseng, for the card of deficiency-weakness of spleen-QI.Radix Angelicae Sinensis can replenishing and activating blood, menstruction regulating and pain relieving, for rheumatic arthralgia.Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, control consumption of YIN caused by febrile disease, Rhizoma Polygonati Odorati can be joined.Rhizoma Polygonati Odorati can nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.The Radix Paeoniae Alba is nourished blood yin fluid astringing, and easing the affected liver to relieve pain can join Radix Bupleuri, Radix Angelicae Sinensis.Radix Bupleuri pungent row hardship is let out, and property is apt to bar and is reached irritability, dispersing the stagnated live-QI to relieve the stagnation of QI, can control and can control stagnation of QI due to depression of the liver.Bulbus Allii Macrostemonis is associated with Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, controls the card of the thoracic obstruction.Radix Platycodonis lung qi dispersing, eliminates the phlegm, and returns lung meridian.Lignum Dalbergiae Odoriferae can dissipate can manage it, energy blood stasis dispelling regulating QI to relieve pain, the available breast side of body trusted subordinate's pain controlling stagnation of QI and blood, is equal to use with Oletum Trogopterori, Rhizoma Chuanxiong.Oletum Trogopterori can promoting blood circulation and stopping pain, removing stasis to stop bleeding, specially enter Liver Channel blood system, be good at promoting blood circulation, removing blood stasis and relieving pain, often with Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae with use.Ramulus Cinnamomi controls heart arteries and veins stasis blocking, obstruction of qi in the chest and cardialgia.Radix Notoginseng can dissipating blood stasis hemostasis, subduing swelling and relieving pain, the same use of compatibility blood-activating and qi-moving medicinal, then the merit of analgesic therapy of invigorating blood circulation more writes.Medulla Tetrapanacis attaches to the lung and stomach meridians, inducing diuresis for treating stranguria syndrome, associates with Radix Glycyrrhizae etc..Styrax controls the diseases such as turbid, the blood stasis of expectorant, is often equal to use with Borneolum Syntheticum.Borneolum Syntheticum GUIXIN, spleen, lung meridian, refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.
Above pharmacology observes " Chinese Pharmacopoeia " (version in 2010) and the herbal medicine efficacy of " Chinese materia medica " (New Century higher institutions of Chinese medicine teaching material) and combination principle.But herbal pharmacology is profound, the summary of above pharmacology the whole pharmacology of non-invention.We are formed by multi-medicament compatibility, jointly act on, and Radix Salviae Miltiorrhizae, Folium Ginkgo are monarch drug, it is possible to distinguish monarch.
Embodiment one
A kind of Chinese medicine formula for treating cardiovascular stasis coronary heart disease, according to the mass fraction, consist of the following composition: Radix Salviae Miltiorrhizae 21g, Folium Ginkgo 18g, Rhizoma Corydalis 14.5g, Rhizoma Chuanxiong 14.5g, Fructus Hordei Germinatus 12.9g, Cortex Moutan 12.9g, Fructus Crataegi 12.9g, Radix Ginseng 11g, Semen Persicae 11g, Stigma Croci 11g, Radix Paeoniae Rubra 11g, Caulis Spatholobi 11g, Fructus Aurantii 9g, Pericarpium Citri Reticulatae 8.6g, Herba Artemisiae Anomalae 8.6g, Radix Glycyrrhizae 8.6g, Radix Angelicae Sinensis 8.6g, Radix Rehmanniae 8.6g, Radix Bupleuri 8.6g, Lignum Dalbergiae Odoriferae 8g, Radix Paeoniae Alba 8g, Bulbus Allii Macrostemonis 8g, Radix Platycodonis 8g, Medulla Tetrapanacis 7g, Oletum Trogopterori 6g, Ramulus Cinnamomi 6g, Rhizoma Polygonati Odorati 6g, Radix Notoginseng 6g, Styrax 5g, Borneolum Syntheticum 0.8g.
A kind of Chinese medicinal pill for treating cardiovascular stasis coronary heart disease, including described Chinese medicine formula and Mel, mass ratio is 1: ~ 1.5.
A kind of Chinese medicine preparation for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and solvent.In this Chinese medicine preparation, described solvent is rice wine, and by mass percentage, it is 1:8 with the proportioning of Chinese medicine formula.
Embodiment two
A kind of Chinese medicine formula for treating cardiovascular stasis coronary heart disease, according to the mass fraction, consist of the following composition: Radix Salviae Miltiorrhizae 20g, Folium Ginkgo 20g, Rhizoma Corydalis 14g, Rhizoma Chuanxiong 14g, Fructus Hordei Germinatus 12.5g, Cortex Moutan 12.5g, Fructus Crataegi 12.5g, Radix Ginseng 10g, Semen Persicae 10g, Stigma Croci 10g, Radix Paeoniae Rubra 10g, Caulis Spatholobi 10g, Fructus Aurantii 10g, Pericarpium Citri Reticulatae 10g, Herba Artemisiae Anomalae 9g, Radix Glycyrrhizae 9g, Radix Angelicae Sinensis 9g, Radix Rehmanniae 9g, Radix Bupleuri 9g, Lignum Dalbergiae Odoriferae 10g, Radix Paeoniae Alba 8g, Bulbus Allii Macrostemonis 8g, Radix Platycodonis 8g, Medulla Tetrapanacis 6g, Oletum Trogopterori 6g, Ramulus Cinnamomi 6g, Rhizoma Polygonati Odorati 6g, Radix Notoginseng 6g, Styrax 4g, Borneolum Syntheticum 1g.
A kind of Chinese medicine preparation for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and solvent.In this Chinese medicine preparation, described solvent is ethanol, and by mass percentage, it is 1:3 with the proportioning of Chinese medicine formula.
Embodiment three
A kind of Chinese medicine formula for treating cardiovascular stasis coronary heart disease, according to the mass fraction, consist of the following composition: Radix Salviae Miltiorrhizae 20.5g, Folium Ginkgo 20g, Rhizoma Corydalis 14g, Rhizoma Chuanxiong 13.8g, Fructus Hordei Germinatus 12.5g, Cortex Moutan 12.5g, Fructus Crataegi 12.5g, Radix Ginseng 10g, Semen Persicae 10g, Stigma Croci 10g, Radix Paeoniae Rubra 10g, Caulis Spatholobi 10g, Fructus Aurantii 10g, Pericarpium Citri Reticulatae 10g, Herba Artemisiae Anomalae 8.8g, Radix Glycyrrhizae 8.6g, Radix Angelicae Sinensis 8.6g, Radix Rehmanniae 8.8g, Radix Bupleuri 8.6g, Lignum Dalbergiae Odoriferae 9g, Radix Paeoniae Alba 8.5g, Bulbus Allii Macrostemonis 8.2g, Radix Platycodonis 8.2g, Medulla Tetrapanacis 6.5g, Oletum Trogopterori 5.9g, Ramulus Cinnamomi 5.8g, Rhizoma Polygonati Odorati 5.8g, Radix Notoginseng 5.8g, Styrax 4.5g, Borneolum Syntheticum 0.9g.
A kind of Chinese medicine preparation for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and solvent.In this Chinese medicine preparation, described solvent is ethanol, and by mass percentage, it is 1:6 with the proportioning of Chinese medicine formula.
Embodiment four
A kind of Chinese medicine formula for treating cardiovascular stasis coronary heart disease, according to the mass fraction, consist of the following composition: Radix Salviae Miltiorrhizae 20g, Folium Ginkgo 21g, Rhizoma Corydalis 13.5g, Rhizoma Chuanxiong 14.5g, Fructus Hordei Germinatus 12g, Cortex Moutan 12g, Fructus Crataegi 12g, Radix Ginseng 10.5g, Semen Persicae 10.5g, Stigma Croci 10.5g, Radix Paeoniae Rubra 10.5g, Caulis Spatholobi 10.5, Fructus Aurantii 11g, Pericarpium Citri Reticulatae 11g, Herba Artemisiae Anomalae 8.9g, Radix Glycyrrhizae 8.9g, Radix Angelicae Sinensis 8.9g, Radix Rehmanniae 8.9g, Radix Bupleuri 8.9g, Lignum Dalbergiae Odoriferae 11g, Radix Paeoniae Alba 9g, Bulbus Allii Macrostemonis 8.5g, Radix Platycodonis 8.5g, Medulla Tetrapanacis 5.5g, Oletum Trogopterori 5.8g, Ramulus Cinnamomi 5.5g, Rhizoma Polygonati Odorati 5.5g, Radix Notoginseng 5.5g, Styrax 4g, Borneolum Syntheticum 1g.
A kind of Chinese medicine preparation for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and solvent.In this Chinese medicine preparation, described solvent is ethanol, and by mass percentage, it is 1:1 with the proportioning of Chinese medicine formula.
Embodiment five
A kind of Chinese medicine formula for treating cardiovascular stasis coronary heart disease, according to the mass fraction, consist of the following composition: Radix Salviae Miltiorrhizae 21g, Folium Ginkgo 21g, Rhizoma Corydalis 15g, Rhizoma Chuanxiong 15g, Fructus Hordei Germinatus 12g, Cortex Moutan 12g, Fructus Crataegi 12g, Radix Ginseng 10g, Semen Persicae 10g, Stigma Croci 10g, Radix Paeoniae Rubra 10g, Caulis Spatholobi 10g, Fructus Aurantii 10g, Pericarpium Citri Reticulatae 10g, Herba Artemisiae Anomalae 9g, Radix Glycyrrhizae 9g, Radix Angelicae Sinensis 9g, Radix Rehmanniae 9g, Radix Bupleuri 9g, Lignum Dalbergiae Odoriferae 10g, Radix Paeoniae Alba 8g, Bulbus Allii Macrostemonis 8g, Radix Platycodonis 8g, Medulla Tetrapanacis 6g, Oletum Trogopterori 6g, Ramulus Cinnamomi 6g, Rhizoma Polygonati Odorati 6g, Radix Notoginseng 6g, Styrax 4g, Borneolum Syntheticum 2g.
A kind of Chinese medicinal pill for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and Mel, mass ratio is 1:1.
A kind of Chinese medicine preparation for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and solvent.In this Chinese medicine preparation, described solvent is yellow wine, and by mass percentage, it is 1:10 with the proportioning of Chinese medicine formula.
Embodiment six
A kind of Chinese medicine formula for treating cardiovascular stasis coronary heart disease, according to the mass fraction, consist of the following composition: Radix Salviae Miltiorrhizae 21g, Folium Ginkgo 21g, Rhizoma Corydalis 13g, Rhizoma Chuanxiong 13g, Fructus Hordei Germinatus 12g, Cortex Moutan 12g, Fructus Crataegi 12g, Radix Ginseng 10g, Semen Persicae 10g, Stigma Croci 10g, Radix Paeoniae Rubra 10g, Caulis Spatholobi 10g, Fructus Aurantii 10g, Pericarpium Citri Reticulatae 10g, Herba Artemisiae Anomalae 9g, Radix Glycyrrhizae 9g, Radix Angelicae Sinensis 9g, Radix Rehmanniae 9g, Radix Bupleuri 9g, Lignum Dalbergiae Odoriferae 10g, Radix Paeoniae Alba 8g, Bulbus Allii Macrostemonis 8g, Radix Platycodonis 8g, Medulla Tetrapanacis 6g, Oletum Trogopterori 6g, Ramulus Cinnamomi 6g, Rhizoma Polygonati Odorati 6g, Radix Notoginseng 6g, Styrax 6g, Borneolum Syntheticum 2g.
A kind of Chinese medicinal pill for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and Mel, mass ratio is 1:0.5.
A kind of Chinese medicine preparation for treating cardiovascular stasis coronary heart disease, it is characterised in that include described Chinese medicine formula and solvent.In this Chinese medicine preparation, described solvent is rice wine, and by mass percentage, it is 1:10 with the proportioning of Chinese medicine formula.
The consumption of each Chinese medicinal components of above example does not represent potion consumption, and in practical operation, general point two daily.The application is not intended to the preparation method of this Chinese medicine formula, according to Chinese Pharmacopoeia, prepares according to usual method, takes.Certainly, using concentration of alcohol aqueous solution more than 40% or drinks according to experimental demonstration, Radix Ginseng and Oletum Trogopterori, slow fire is decocted three hours, is eating with other component compatibilities, better.
Typical case
1, Nanchang City, Jiangxi Province sieve family collection sieve XX, long-term chest pain, enter Night Watch very, and with palpitation and uneasiness.Once sought medical advice in First Affiliated Hospital Of Nanchang University of Jiangxi Province, checked that result was for treatment cardiovascular stasis coronary heart disease angina pectoris.Because curative effect is inconspicuous, chest pain has no improvement, actively abandons curing.After using our half a year, chest pain does not recurs.
2, Duchang County, Jiangxi Cai Ling town XXX, suffers from hypertension and with long-term chest pain, once Duchang County the People's Hospital treatment, invalid after proceed to First Affiliated Hospital Of Nanchang University of Jiangxi Province.Determining suffer from the angina pectoris caused by hypertension in an attached institute, main dialectical type is type of obstruction of heart-blood.Due to many reasons, its abandoning cure.Using we the year before, through the long-term treatment of ten wheat harvesting periods, chest pain gradually slows down, and has disappeared, and hypertension has been alleviated.
Each Chinese medicinal components of above example may be used for treating cardiovascular stasis coronary heart disease angina pectoris.It is about 90% to the cure rate of the angina pectoris based on stagnation of heart-blood, if coronary heart disease is by caused by hypertension and hyperlipidemia, cure rate is about 92%.Additionally, the cure rate causing anginal hypertension and hyperlipidemia is about 76%.

Claims (4)

1. the Chinese medicine being used for treating cardiovascular stasis coronary heart disease, it is characterized in that, according to the mass fraction, consist of the following composition: Radix Salviae Miltiorrhizae 210 parts, Folium Ginkgo 180 parts, Rhizoma Corydalis 145 parts, Rhizoma Chuanxiong 145 parts, 129 parts of Fructus Hordei Germinatus, Cortex Moutan 129 parts, Fructus Crataegi 129 parts, Radix Ginseng 110 parts, 110 parts of Semen Persicae, Stigma Croci 110 parts, Radix Paeoniae Rubra 110 parts, Caulis Spatholobi 110 parts, Fructus Aurantii 90 parts, Pericarpium Citri Reticulatae 86 parts, Herba Artemisiae Anomalae 86 parts, 86 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 86 parts, 86 parts of the Radix Rehmanniae, Radix Bupleuri 86 parts, Lignum Dalbergiae Odoriferae 80 parts, the Radix Paeoniae Alba 80 parts, Bulbus Allii Macrostemonis 80 parts, Radix Platycodonis 80 parts, Medulla Tetrapanacis 70 parts, Oletum Trogopterori 60 parts, Ramulus Cinnamomi 60 parts, Rhizoma Polygonati Odorati 60 parts, Radix Notoginseng 60 parts, Styrax 50 parts, Borneolum Syntheticum 8 parts, described Fructus Hordei Germinatus is Fructus Hordei Germinatus (parched).
2. the Chinese medicinal capsule being used for treating cardiovascular stasis coronary heart disease, it is characterised in that include Chinese medicine as claimed in claim 1.
3. the Chinese medicinal pill being used for treating cardiovascular stasis coronary heart disease, it is characterised in that including Chinese medicine as claimed in claim 1 and Mel, mass ratio is 1:0.5 ~ 1.5.
4. the Chinese medicine preparation being used for treating cardiovascular stasis coronary heart disease, it is characterised in that include Chinese medicine as claimed in claim 1 and solvent.
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