CN103783513B - A kind of radish seed Chinese yam dispersible tablet and preparation method - Google Patents
A kind of radish seed Chinese yam dispersible tablet and preparation method Download PDFInfo
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- CN103783513B CN103783513B CN201310748511.7A CN201310748511A CN103783513B CN 103783513 B CN103783513 B CN 103783513B CN 201310748511 A CN201310748511 A CN 201310748511A CN 103783513 B CN103783513 B CN 103783513B
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- 235000006140 Raphanus sativus var sativus Nutrition 0.000 title claims abstract description 38
- 235000002722 Dioscorea batatas Nutrition 0.000 title claims abstract description 30
- 235000006536 Dioscorea esculenta Nutrition 0.000 title claims abstract description 30
- 240000001811 Dioscorea oppositifolia Species 0.000 title claims abstract description 30
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 title claims abstract description 30
- 239000007919 dispersible tablet Substances 0.000 title claims abstract description 19
- 244000088415 Raphanus sativus Species 0.000 title claims abstract 5
- 238000002360 preparation method Methods 0.000 title description 9
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- 241000287828 Gallus gallus Species 0.000 claims abstract description 19
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 18
- 239000000843 powder Substances 0.000 claims abstract description 15
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 11
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims abstract description 11
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 11
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229920002472 Starch Polymers 0.000 claims abstract description 11
- 239000004376 Sucralose Substances 0.000 claims abstract description 11
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims abstract description 11
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims abstract description 11
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 11
- 229940107666 astragalus root Drugs 0.000 claims abstract description 11
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 11
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims abstract description 11
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims abstract description 11
- RQFQJYYMBWVMQG-IXDPLRRUSA-N chitotriose Chemical compound O[C@@H]1[C@@H](N)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](N)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](CO)O1 RQFQJYYMBWVMQG-IXDPLRRUSA-N 0.000 claims abstract description 11
- 235000020717 hawthorn extract Nutrition 0.000 claims abstract description 11
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 11
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 11
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 11
- 239000000741 silica gel Substances 0.000 claims abstract description 11
- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 11
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 11
- 239000011734 sodium Substances 0.000 claims abstract description 11
- 239000008107 starch Substances 0.000 claims abstract description 11
- 235000019698 starch Nutrition 0.000 claims abstract description 11
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims abstract description 11
- 235000019408 sucralose Nutrition 0.000 claims abstract description 11
- 235000019155 vitamin A Nutrition 0.000 claims abstract description 11
- 239000011719 vitamin A Substances 0.000 claims abstract description 11
- 229940045997 vitamin a Drugs 0.000 claims abstract description 11
- 235000011478 zinc gluconate Nutrition 0.000 claims abstract description 11
- 239000011670 zinc gluconate Substances 0.000 claims abstract description 11
- 229960000306 zinc gluconate Drugs 0.000 claims abstract description 11
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 9
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 9
- 239000011718 vitamin C Substances 0.000 claims abstract description 9
- 239000004615 ingredient Substances 0.000 claims abstract description 7
- 206010012735 Diarrhoea Diseases 0.000 abstract description 6
- 210000000952 spleen Anatomy 0.000 abstract description 5
- 230000007812 deficiency Effects 0.000 abstract description 2
- 241000220259 Raphanus Species 0.000 description 33
- 238000002156 mixing Methods 0.000 description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 13
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 12
- 239000002245 particle Substances 0.000 description 12
- 235000004879 dioscorea Nutrition 0.000 description 8
- 238000001035 drying Methods 0.000 description 8
- 239000000706 filtrate Substances 0.000 description 8
- 235000013312 flour Nutrition 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 239000002994 raw material Substances 0.000 description 8
- PTHCMJGKKRQCBF-UHFFFAOYSA-N Cellulose, microcrystalline Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC)C(CO)O1 PTHCMJGKKRQCBF-UHFFFAOYSA-N 0.000 description 4
- 238000009835 boiling Methods 0.000 description 4
- 229940105329 carboxymethylcellulose Drugs 0.000 description 4
- 239000006071 cream Substances 0.000 description 4
- 239000012535 impurity Substances 0.000 description 4
- 238000001556 precipitation Methods 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000006228 supernatant Substances 0.000 description 4
- 238000001291 vacuum drying Methods 0.000 description 4
- 206010047700 Vomiting Diseases 0.000 description 3
- 230000008673 vomiting Effects 0.000 description 3
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 208000019637 Infantile Diarrhea Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000000378 dietary effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 208000034782 Lid sulcus deepened Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 235000011837 pasties Nutrition 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940126672 traditional medicines Drugs 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Health & Medical Sciences (AREA)
- Mycology (AREA)
- Botany (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Fruits And Vegetables (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of radish seed Chinese yam dispersible tablet, comprise following parts by weight ingredient: radish seed 120-200 part, the membrane of a chicken's gizzard 40-80 part, Chinese yam 200-400 part, vitamin C? 1.75-3.75 part, vitamin A? 0.01-0.02 part, zinc gluconate 0.15-0.35 part, microcrystalline cellulose 40-60 part, Astragalus Root P.E 0.12-0.32 part, haw thorn extract 0.12-0.32 part, sweet mellow wine 100-170 part, chitosan oligosaccharide 1.2-3.2 part, Thick many candies 1.2-3.2 part, Sucralose 10-15 part, superfine silica gel powder 10-50 part, carboxymethyl cellulose 3-5 part, sodium carboxymethyl starch 55-80 part, dolomol 4-6 part, 75% concentration ethanol is appropriate.The present invention has invigorating the spleen to arrest diarrhea.Be applicable to that infantile spleen deficiency rushes down for a long time, large loose stool is thin.
Description
Technical field
The invention belongs to nutritional health food field, be specially a kind of radish seed Chinese yam dispersible tablet and preparation method.
Background technology
Infantile diarrhea increases with times of defecation, excrement matter thin or as water sample be its main symptom, especially more common with the infant of less than 2 years old.Summer and autumn are more, and often cause popular.This sick clinical manifestation weight great disparity, the lighter is just seldom secondary, and loose stool is as pasty state, or as egg flower, even body heat is not generated heat, without vomiting, can take food, spirit is fair.Severe one then just secondary comparatively frequently, one day Nei Keda more than more than ten time or tens of time, or companion's vomiting, many companion's body heat, One's spirits are drooping, or have the fidgets, incessantly thirsty, even sunken eyes, hypourocrinia, four limbs are not warm, abdominal distension, convulsion are fainted.Clinical manifestation: abdominal fullness and distention, stomachache, pain then subtracts for rushing down, rushing down rear pain, and ight soil acid is smelly or as lost ovum, belch acid, turns sour, vomiting, does not think breast food, uneasy sleeping at night, and tongue is thick greasy, or micro-Huang.Although also have Chinese Traditional Medicines or the formula of a lot of infantile diarrhea at present, although treatment prescribed preparation is a lot, be all occur with the form of medicine, the dietary product being applicable to long-term edible supplemental treatment is little.Therefore the dietary product researching and developing a kind of safe adjunct therapy is very with practical value.
Summary of the invention
For above-mentioned situation, technical problem solved by the invention is to provide a kind of radish seed Chinese yam dispersible tablet and preparation method of invigorating the spleen to arrest diarrhea, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of radish seed Chinese yam dispersible tablet, comprise following parts by weight ingredient: radish seed 120-200 part, the membrane of a chicken's gizzard 40-80 part, Chinese yam 200-400 part, vitamin C 1.75-3.75 part, vitamin A 0.01-0.02 part, zinc gluconate 0.15-0.35 part, microcrystalline cellulose 40-60 part, Astragalus Root P.E 0.12-0.32 part, haw thorn extract 0.12-0.32 part, sweet mellow wine 100-170 part, chitosan oligosaccharide 1.2-3.2 part, Thick many candies 1.2-3.2 part, Sucralose 10-15 part, superfine silica gel powder 10-50 part, carboxymethyl cellulose 3-5 part, sodium carboxymethyl starch 55-80 part, dolomol 4-6 part, 75% concentration ethanol is appropriate.
As preferably, described a kind of radish seed Chinese yam dispersible tablet, comprises following parts by weight ingredient: radish seed 160 parts, the membrane of a chicken's gizzard 60 parts, Chinese yam 300 parts, Catergen .75 part, vitamin A 0.015 part, zinc gluconate 0.25 part, microcrystalline cellulose 50 parts, Astragalus Root P.E 0.22 part, haw thorn extract 0.22 part, 135 parts, sweet mellow wine, chitosan oligosaccharide 2.2 parts, Thick many candies 2.2 parts, Sucralose 12.5 parts, superfine silica gel powder 30 parts, carboxymethyl cellulose 4 parts, sodium carboxymethyl starch 67.5 parts, dolomol 5 parts, 75% concentration ethanol are appropriate.
A preparation method for radish seed Chinese yam dispersible tablet, comprises the following steps:
(1) get fresh Chinese yam to clean, scrape off crust, soak 10-12h with 0.5% aqueous citric acid solution, take out, take the dish out of the pot after the boiling water putting into 100 DEG C boils 10-20min, be down to room temperature, then carry out drying, baking temperature is 60-80 DEG C, time is 1-2.5h, then pulverizes, and is ground into 300-500 order powder, obtain yam flour, for subsequent use;
(2) get raw material radish seed, the membrane of a chicken's gizzard is cleaned, add above-mentioned raw materials gross mass 3-5 times amount soak by water doubly 2-3 time, filter, merging filtrate, filtrate is concentrated into the clear cream that relative density within the scope of 50-65 DEG C is 1.05, adding ethanol makes alcohol content be 60-85%, leaves standstill 18-24h, makes precipitation, get supernatant, reclaiming ethanol and being concentrated into relative density within the scope of 60-80 DEG C is the paste of 1.15, obtains radish seed the membrane of a chicken's gizzard thick paste, for subsequent use;
(3) be uniformly mixed by gained radish seed the membrane of a chicken's gizzard thick paste in step (1) gained yam flour and step (2), mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, Vacuum Concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, Astragalus Root P.E, haw thorn extract, sweet mellow wine, chitosan oligosaccharide, Thick many candies, Sucralose, superfine silica gel powder mixing machine mixing make particle, rotating speed is 10-15r/min, time is 6-8min, by mixing after particle 50-60 DEG C of scope inner drying to water content between 1-3%, for subsequent use;
(6) add sodium carboxymethyl starch, dolomol mixing to gained particle in step (5), tabletted, obtains radish seed Chinese yam dispersible tablet.
In sum, beneficial effect of the present invention:
The present invention has invigorating the spleen to arrest diarrhea.Be applicable to that infantile spleen deficiency rushes down for a long time, large loose stool is thin.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described gained technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on gained embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A kind of radish seed Chinese yam dispersible tablet, comprises following parts by weight ingredient: radish seed 120 parts, the membrane of a chicken's gizzard 40 parts, Chinese yam 200 parts, vitamin C 1.75 parts, vitamin A 0.01 part, zinc gluconate 0.15 part, microcrystalline cellulose 40 parts, Astragalus Root P.E 0.12 part, haw thorn extract 0.12 part, 100 parts, sweet mellow wine, chitosan oligosaccharide 1.2 parts, Thick many candies 1.2 parts, Sucralose 10 parts, superfine silica gel powder 10 parts, carboxymethyl cellulose 3 parts, sodium carboxymethyl starch 55 parts, dolomol 4 parts, 75% concentration ethanol are appropriate.
A preparation method for radish seed Chinese yam dispersible tablet, comprises the following steps:
(1) get fresh Chinese yam to clean, scrape off crust, soak 10-12h with 0.5% aqueous citric acid solution, take out, take the dish out of the pot after the boiling water putting into 100 DEG C boils 10-20min, be down to room temperature, then carry out drying, baking temperature is 60-80 DEG C, time is 1-2.5h, then pulverizes, and is ground into 300-500 order powder, obtain yam flour, for subsequent use;
(2) get raw material radish seed, the membrane of a chicken's gizzard is cleaned, add above-mentioned raw materials gross mass 3-5 times amount soak by water doubly 2-3 time, filter, merging filtrate, filtrate is concentrated into the clear cream that relative density within the scope of 50-65 DEG C is 1.05, adding ethanol makes alcohol content be 60-85%, leaves standstill 18-24h, makes precipitation, get supernatant, reclaiming ethanol and being concentrated into relative density within the scope of 60-80 DEG C is the paste of 1.15, obtains radish seed the membrane of a chicken's gizzard thick paste, for subsequent use;
(3) be uniformly mixed by gained radish seed the membrane of a chicken's gizzard thick paste in step (1) gained yam flour and step (2), mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, Vacuum Concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, Astragalus Root P.E, haw thorn extract, sweet mellow wine, chitosan oligosaccharide, Thick many candies, Sucralose, superfine silica gel powder mixing machine mixing make particle, rotating speed is 10-15r/min, time is 6-8min, by mixing after particle 50-60 DEG C of scope inner drying to water content between 1-3%, for subsequent use;
(6) add sodium carboxymethyl starch, dolomol mixing to gained particle in step (5), tabletted, obtains radish seed Chinese yam dispersible tablet.
Embodiment 2
A kind of radish seed Chinese yam dispersible tablet, comprises following parts by weight ingredient: radish seed 160 parts, the membrane of a chicken's gizzard 60 parts, Chinese yam 300 parts, Catergen .75 part, vitamin A 0.015 part, zinc gluconate 0.25 part, microcrystalline cellulose 50 parts, Astragalus Root P.E 0.22 part, haw thorn extract 0.22 part, 135 parts, sweet mellow wine, chitosan oligosaccharide 2.2 parts, Thick many candies 2.2 parts, Sucralose 12.5 parts, superfine silica gel powder 30 parts, carboxymethyl cellulose 4 parts, sodium carboxymethyl starch 67.5 parts, dolomol 5 parts, 75% concentration ethanol are appropriate.
A preparation method for radish seed Chinese yam dispersible tablet, comprises the following steps:
(1) get fresh Chinese yam to clean, scrape off crust, soak 10-12h with 0.5% aqueous citric acid solution, take out, take the dish out of the pot after the boiling water putting into 100 DEG C boils 10-20min, be down to room temperature, then carry out drying, baking temperature is 60-80 DEG C, time is 1-2.5h, then pulverizes, and is ground into 300-500 order powder, obtain yam flour, for subsequent use;
(2) get raw material radish seed, the membrane of a chicken's gizzard is cleaned, add above-mentioned raw materials gross mass 3-5 times amount soak by water doubly 2-3 time, filter, merging filtrate, filtrate is concentrated into the clear cream that relative density within the scope of 50-65 DEG C is 1.05, adding ethanol makes alcohol content be 60-85%, leaves standstill 18-24h, makes precipitation, get supernatant, reclaiming ethanol and being concentrated into relative density within the scope of 60-80 DEG C is the paste of 1.15, obtains radish seed the membrane of a chicken's gizzard thick paste, for subsequent use;
(3) be uniformly mixed by gained radish seed the membrane of a chicken's gizzard thick paste in step (1) gained yam flour and step (2), mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, Vacuum Concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, Astragalus Root P.E, haw thorn extract, sweet mellow wine, chitosan oligosaccharide, Thick many candies, Sucralose, superfine silica gel powder mixing machine mixing make particle, rotating speed is 10-15r/min, time is 6-8min, by mixing after particle 50-60 DEG C of scope inner drying to water content between 1-3%, for subsequent use;
(6) add sodium carboxymethyl starch, dolomol mixing to gained particle in step (5), tabletted, obtains radish seed Chinese yam dispersible tablet.
Embodiment 3
A kind of radish seed Chinese yam dispersible tablet, comprises following parts by weight ingredient: radish seed 200 parts, the membrane of a chicken's gizzard 80 parts, Chinese yam 400 parts, vitamin C 3.75 parts, vitamin A 0.02 part, zinc gluconate 0.35 part, microcrystalline cellulose 60 parts, Astragalus Root P.E 0.32 part, haw thorn extract 0.32 part, 170 parts, sweet mellow wine, chitosan oligosaccharide 3.2 parts, Thick many candies 3.2 parts, Sucralose 15 parts, superfine silica gel powder 50 parts, carboxymethyl cellulose 5 parts, sodium carboxymethyl starch 80 parts, dolomol 6 parts, 75% concentration ethanol are appropriate.
A preparation method for radish seed Chinese yam dispersible tablet, comprises the following steps:
(1) get fresh Chinese yam to clean, scrape off crust, soak 10-12h with 0.5% aqueous citric acid solution, take out, take the dish out of the pot after the boiling water putting into 100 DEG C boils 10-20min, be down to room temperature, then carry out drying, baking temperature is 60-80 DEG C, time is 1-2.5h, then pulverizes, and is ground into 300-500 order powder, obtain yam flour, for subsequent use;
(2) get raw material radish seed, the membrane of a chicken's gizzard is cleaned, add above-mentioned raw materials gross mass 3-5 times amount soak by water doubly 2-3 time, filter, merging filtrate, filtrate is concentrated into the clear cream that relative density within the scope of 50-65 DEG C is 1.05, adding ethanol makes alcohol content be 60-85%, leaves standstill 18-24h, makes precipitation, get supernatant, reclaiming ethanol and being concentrated into relative density within the scope of 60-80 DEG C is the paste of 1.15, obtains radish seed the membrane of a chicken's gizzard thick paste, for subsequent use;
(3) be uniformly mixed by gained radish seed the membrane of a chicken's gizzard thick paste in step (1) gained yam flour and step (2), mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, Vacuum Concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, Astragalus Root P.E, haw thorn extract, sweet mellow wine, chitosan oligosaccharide, Thick many candies, Sucralose, superfine silica gel powder mixing machine mixing make particle, rotating speed is 10-15r/min, time is 6-8min, by mixing after particle 50-60 DEG C of scope inner drying to water content between 1-3%, for subsequent use;
(6) add sodium carboxymethyl starch, dolomol mixing to gained particle in step (5), tabletted, obtains radish seed Chinese yam dispersible tablet.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or essential characteristic, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and in each embodiment, gained technical scheme also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (1)
1. a radish seed Chinese yam dispersible tablet, it is characterized in that: be made up of following parts by weight ingredient: radish seed 120-200 part, the membrane of a chicken's gizzard 40-80 part, Chinese yam 200-400 part, vitamin C 1.75-3.75 part, vitamin A 0.01-0.02 part, zinc gluconate 0.15-0.35 part, microcrystalline cellulose 40-60 part, Astragalus Root P.E 0.12-0.32 part, haw thorn extract 0.12-0.32 part, sweet mellow wine 100-170 part, chitosan oligosaccharide 1.2-3.2 part, Thick many candies 1.2-3.2 part, Sucralose 10-15 part, superfine silica gel powder 10-50 part, carboxymethyl cellulose 3-5 part, sodium carboxymethyl starch 55-80 part, dolomol 4-6 part, 75% concentration ethanol is appropriate.
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| KR20030041921A (en) * | 2003-04-22 | 2003-05-27 | 최재승 | The method of diabetes prevention gem |
| CN1895575A (en) * | 2006-06-19 | 2007-01-17 | 上海玉森新药开发有限公司 | Medicine for treating infantile anorexia and its preparation |
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