CN103768433A - Traditional Chinese medicine preparation for treating spleen-stomach deficiency chronic gastritis - Google Patents
Traditional Chinese medicine preparation for treating spleen-stomach deficiency chronic gastritis Download PDFInfo
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- CN103768433A CN103768433A CN201410020778.9A CN201410020778A CN103768433A CN 103768433 A CN103768433 A CN 103768433A CN 201410020778 A CN201410020778 A CN 201410020778A CN 103768433 A CN103768433 A CN 103768433A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating spleen-stomach deficiency chronic gastritis. The pathogenesis of the spleen-stomach deficiency chronic gastritis mainly consists in an asthenic disease of the spleen and stomach; the spleen (stomach) is the foundation of acquired constitution, and the source for generating and transforming qi and blood; engendering transformation is insufficient due to spleen deficiency, resulting in a plurality of diseases, namely spleen-asthenia with excessive damp, chronic dyspepsia converting into pathogenic heat and impairment of yin. The traditional Chinese medicines with the effects of warming middle-burner and invigorating the spleen, harmonizing the stomach and lowering adverse qi, and replenishing qi and strengthening the middle warmer, such as textile screw pine seed, yunnan rhodiola root, polished round-grained rice, inula helenium, kumquat leaves, medicago falcate, vanillagrass inflorescence, falsesour cherry leaves, inula helenium, tsingling bergenia rhizome and buddhist bauhinia bark are selected to be decocted into decoction. The total effective rate is 95.9%, and obviously superior to 83.6% of a control group by a clinical test in the hospital, and a sufferer in a treatment group does not generate obvious bad reaction in the treatment process.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of due to weakness of spleen and stomach chronic gastritis.
Background technology
Chronic gastritis is the chronic gastric mucosa inflammatory lesion being caused by Different types of etiopathogenises, is also commonly encountered diseases, frequently-occurring disease clinically.Doctor trained in Western medicine still lacks effective treatment means to this disease especially chronic atrophic gastritis at present.Primary disease still lacks the Western medicine of determined curative effect, few side effects at present, and treatment by Chinese herbs has its unique advantage, adopts in recent years Chinese traditional treatment to obtain good clinical effectiveness.Chinese traditional treatment is dialectical executes doctor, for the feature a little less than liver insufficiency of stomach, uses the treatment by Chinese herbs with warming middle-JIAO and strengthening the spleen, regulating the stomach and sending down the abnormal ascending QI, QI invigorating invigorating middle warmer effect, and effect is remarkable, and relapse rate is low.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of due to weakness of spleen and stomach chronic gastritis.Chronic gastritis belongs to the categories such as motherland's medical science " gastric abscess ", " syndrome of feeling fullness and distension in the upper abdomen " according to its clinical manifestation.It is deficient in taste that its pathogenesis of due to weakness of spleen and stomach chronic gastritis is mainly blamed, and spleen (stomach) is the basis day after tomorrow, and source of generating QI and blood is insufficiency of the spleen biochemical not enough, just sick all; Spleen-asthenia with excessive damp, the strongly fragrant heat-transformation of a specified duration of turbid damp, and can impairment of YIN.Control with warming middle-JIAO and strengthening the spleen regulating the stomach and sending down the abnormal ascending QI, QI invigorating invigorating middle warmer.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment due to weakness of spleen and stomach chronic gastritis is made up of the Chinese medicine of following weight portion: Fructus Pandani tectorii 9-15 part, Pedicularis rex C. B. Clarke ex Maxim. 15-25 part, Semen oryzae sativae 30-40 part, Radix Inulae 3-6 part, Folium Fortunellae Margarita 3-9 part, Herba medicaginis falcatae 9-15 part, Flos Hierochloes adoratae 10-20 part, Folium Pruni pseudocerasi 10-20 part, Rhizoma Bergeniae scopulosae 6-9 part, Cortex Bauhiniae Variegatae 15-25 part.
Preferably, 12 parts of Fructus Pandani tectoriis, 20 parts of Pedicularis rex C. B. Clarke ex Maxim., 35 parts of Semen oryzae sativaes, 4 parts of Radix Inulaes, 6 parts of Folium Fortunellae Margaritas, 12 parts of Herba medicaginis falcatae, 15 parts of Flos Hierochloes adorataes, 15 parts of Folium Pruni pseudocerasis, 7 parts, Rhizoma Bergeniae scopulosae, 20 parts of Cortex Bauhiniae Variegataes.
Above-mentioned Chinese medicine decocting is made decoction by preparation method.
In side: Fructus Pandani tectorii benefiting vital QI and blood, strengthening the spleen and stomach, the wide painful abdominal mass of expectorant; Pedicularis rex C. B. Clarke ex Maxim. benefiting vital QI and blood, spleen reinforcing dampness removing; Semen oryzae sativae QI invigorating warming middle-JIAO, nourishing the stomach and spleen, dehumidifying antidiarrheal; Radix Inulae promoting the circulation of QI to relieve pain, invigorating the spleen and regulating the stomach; Folium Fortunellae Margarita depressed liver-energy dispersing and QI regulating, appetizing; The Herba medicaginis falcatae alleviating distention in middle-JIAO therapeutic method to keep the adverse QI flowing downwards, spleen invigorating tonify deficiency; Flos Hierochloes adoratae stomach warming pain relieving preventing or arresting vomiting; The spleen invigorating of Folium Pruni pseudocerasi stomach warming, hemostasis removing toxic substances; Rhizoma Bergeniae scopulosae astringent therapy is consolidated intestinal, spleen reinforcing stomach invigorating, eliminating dampness and promoting diuresis, is invigorated blood circulation; Cortex Bauhiniae Variegatae convergence stomach invigorating, eliminating inflammation and expelling toxin.
Clinical data
1, the routine patient of physical data 146 all meets the diagnostic criteria of due to weakness of spleen and stomach chronic gastritis, is divided at random each 73 examples for the treatment of group and matched group.Treatment group: male 43 examples, female's 30 examples, 18～65 years old age, average 39.6 years old, the course of disease 5 months～3 years.Matched group man 45 examples, female's 28 examples, the age is 19～67 years old, average 40.2 years old, the course of disease 5 months～3 years.Two groups at aspects such as sex, age, the course of disease, the state of an illness without significant difference (P>0.05), there is comparability.
2, diagnostic criteria main syndromes: (1) vague epigastralgia.(2) happiness of stomachache pain relieved by pressing is warm.(3) feeling of distension and oppression feeling of fullness after food.(4) appetite stimulator.(5) loose stool diarrhoea.(6) weak extremity are aching and limp.Less important syndrome: (1) gastric mucosa is red and white with Bai Weizhu.(2) mucus is thin and many.(3) gastric acid is on the low side.Picture of the tongue pulse condition: (1) body of the tongue is light red, white and thin fur or white, has indentation.(2) deep-thready pulse.
Pattern of syndrome is determined: (1) possesses 3 of main symptoms, and tongue arteries and veins meets substantially.(2) possess 1 of two of primary symptoms and time disease, tongue arteries and veins meets substantially.Possessing any 1 can determine.
3, Therapeutic Method treatment group is taken Chinese medicine preparation of the present invention, take Fructus Pandani tectorii 12g, Pedicularis rex C. B. Clarke ex Maxim. 20g, Semen oryzae sativae 35g, Radix Inulae 4g, Folium Fortunellae Margarita 6g, Herba medicaginis falcatae 12g, Flos Hierochloes adoratae 15g, Folium Pruni pseudocerasi 15g, Rhizoma Bergeniae scopulosae 7g, Cortex Bauhiniae Variegatae 20g, decocting becomes decoction, potion, divided and sooner or later took for 2 times every day.Matched group is taken famotidine 20mg, and every day, 2 treatments, added cisapride 5mg, every day 3 times.Within 4 weeks, be a course for the treatment of, all treat two courses for the treatment of for two groups.
4, criterion of therapeutical effect (1) Short Term Clinical is cured: comprise following all indexs: 1. clinical cardinal symptom disappears, and less important disease substantially disappears or disappears.2. gastroscope check Active inflammation disappears, and chronic inflammatory disease is pass on well slightly.3. biopsy proved by pathology gastroscope finding; Body of gland atrophy, intestinal and dysplasia be normal or disappearance again.4. gastric acid recovers normally substantially, and bile reflux disappears.
(2) effective: to comprise following all indexs: 1. clinical cardinal symptom disappears, and inferior disease disappears substantially.2. gastroscope check mucosa acute inflammation disappears substantially, and chronic inflammatory disease takes a turn for the better.3. biopsy proved by pathology gastroscope finding; Body of gland atrophy.Intestinalization life and dysplasia recover or alleviate to reach two level degree above (containing two level degree).4. Acid Secretion and bile reflux are improved, and reach the more than 2/3 of former sick exceptional value amount.
(3) effective: to comprise following all indexs: 1. cardinal symptom obviously alleviates.2. gastroscopy mucosa infection scope is dwindled more than 1/2, and inflammation alleviates to some extent.3. biopsy proved by pathology gastroscope finding, more than Acute and chronic inflammation alleviates a level degree, body of gland atrophy, intestinalization life and dysplasia alleviate.4. Acid Secretion and bile reflux are improved, and reach the more than 1/2 of former sick exceptional value amount.
(4) invalid: the case that does not reach effective standard.
5, curative effect comparison after two courses for the treatment of of two groups of therapeutic outcomes treatment, treatment group 73 examples, wherein cure 25 examples (34.2%), effective 24 examples (32.9%), effective 21 examples (28.8%), invalid 3 examples (4.1%), total effective rate 95.9%; Matched group 73 examples, wherein cure 14 examples (19.2%), effective 20 examples (27.4%), effective 27 examples (37%), invalid 12 examples (16.4%), total effective rate 83.6%.Two groups of comparisons, treatment group cure rate, total effective rate are obviously better than matched group, have comparability (P<0.05).In therapeutic process, treatment group patient does not have obvious adverse reaction, and matched group small number of patients can have xerostomia, dizziness, insomnia, constipation, diarrhoea, erythra, flush.Occasionally have leukopenia, slight transaminase increases etc.After drug withdrawal, symptom fades away.
The specific embodiment
Embodiment mono-: take Fructus Pandani tectorii 12g, Pedicularis rex C. B. Clarke ex Maxim. 20g, Semen oryzae sativae 35g, Radix Inulae 4g, Folium Fortunellae Margarita 6g, Herba medicaginis falcatae 12g, Flos Hierochloes adoratae 15g, Folium Pruni pseudocerasi 15g, Rhizoma Bergeniae scopulosae 7g, Cortex Bauhiniae Variegatae 20g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment bis-: take Fructus Pandani tectorii 15g, Pedicularis rex C. B. Clarke ex Maxim. 15g, Semen oryzae sativae 40g, Radix Inulae 3g, Folium Fortunellae Margarita 9g, Herba medicaginis falcatae 9g, Flos Hierochloes adoratae 20g, Folium Pruni pseudocerasi 10g, Rhizoma Bergeniae scopulosae 9g, Cortex Bauhiniae Variegatae 15g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment tri-: take Fructus Pandani tectorii 9g, Pedicularis rex C. B. Clarke ex Maxim. 25g, Semen oryzae sativae 30g, Radix Inulae 6g, Folium Fortunellae Margarita 3g, Herba medicaginis falcatae 15g, Flos Hierochloes adoratae 10g, Folium Pruni pseudocerasi 20g, Rhizoma Bergeniae scopulosae 6g, Cortex Bauhiniae Variegatae 25g, above-mentioned Chinese medicine decocting is become to decoction.
Claims (2)
1. treat a Chinese medicine preparation for due to weakness of spleen and stomach chronic gastritis, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Fructus Pandani tectorii 9-15 part, Pedicularis rex C. B. Clarke ex Maxim. 15-25 part, Semen oryzae sativae 30-40 part, Radix Inulae 3-6 part, Folium Fortunellae Margarita 3-9 part, Herba medicaginis falcatae 9-15 part, Flos Hierochloes adoratae 10-20 part, Folium Pruni pseudocerasi 10-20 part, Rhizoma Bergeniae scopulosae 6-9 part, Cortex Bauhiniae Variegatae 15-25 part.
2. a kind of Chinese medicine preparation for the treatment of due to weakness of spleen and stomach chronic gastritis as claimed in claim 1, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: 12 parts of Fructus Pandani tectoriis, 20 parts of Pedicularis rex C. B. Clarke ex Maxim., 35 parts of Semen oryzae sativaes, 4 parts of Radix Inulaes, 6 parts of Folium Fortunellae Margaritas, 12 parts of Herba medicaginis falcatae, 15 parts of Flos Hierochloes adorataes, 15 parts of Folium Pruni pseudocerasis, 7 parts, Rhizoma Bergeniae scopulosae, 20 parts of Cortex Bauhiniae Variegataes.
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| CN201410020778.9A CN103768433B (en) | 2014-01-12 | 2014-01-12 | A kind of Chinese medicine preparation for the treatment of due to weakness of spleen and stomach chronic gastritis |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366592A (en) * | 2011-09-13 | 2012-03-07 | 孟德芹 | Preparation method of traditional Chinese medicine for treatment of diet stagnation type gastritis |
| CN102669554A (en) * | 2012-05-04 | 2012-09-19 | 蓝照斓 | Red rafter seed health-care noodle |
| CN102988912A (en) * | 2011-09-16 | 2013-03-27 | 董根荣 | Oral liquid for treating chronic superficial gastritis, and preparation method thereof |
| CN103141625A (en) * | 2013-02-20 | 2013-06-12 | 蓝照斓 | Medicago falcata health-care tea |
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- 2014-01-12 CN CN201410020778.9A patent/CN103768433B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366592A (en) * | 2011-09-13 | 2012-03-07 | 孟德芹 | Preparation method of traditional Chinese medicine for treatment of diet stagnation type gastritis |
| CN102988912A (en) * | 2011-09-16 | 2013-03-27 | 董根荣 | Oral liquid for treating chronic superficial gastritis, and preparation method thereof |
| CN102669554A (en) * | 2012-05-04 | 2012-09-19 | 蓝照斓 | Red rafter seed health-care noodle |
| CN103141625A (en) * | 2013-02-20 | 2013-06-12 | 蓝照斓 | Medicago falcata health-care tea |
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Effective date of registration: 20170525 Address after: 226100, No. 588, Jinyang Road, Yue Yue town, Haimen, Jiangsu, Nantong Patentee after: Haimen Yue Yue Textile Co.,Ltd. Address before: The eastern section of Jiefang Road 276000 Shandong province Lanshan District of Linyi City No. 27 people's Hospital of Linyi City Patentee before: Lou Changli |
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