CN103766339A - Composition containing trans-cinnamaldehyde - Google Patents

Composition containing trans-cinnamaldehyde Download PDF

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CN103766339A
CN103766339A CN201310567966.9A CN201310567966A CN103766339A CN 103766339 A CN103766339 A CN 103766339A CN 201310567966 A CN201310567966 A CN 201310567966A CN 103766339 A CN103766339 A CN 103766339A
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composition
quality percentage
percentage composition
care compositions
trans
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CN103766339B (en
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宋瑜丽
于录
唐旭东
申凤鸽
许剑怡
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Shenzhen songzhile Biotechnology Co., Ltd
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SHENZHEN SONGLE BIOTECHNOLOGY CO Ltd
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Abstract

A composition for killing mites contains trans-cinnamaldehyde, a surfactant and a solvent, wherein the weight percent of the trans-cinnamaldehyde is 0.0084-0.268 percent, and the weight percent of the surfactant is 0.5-2 percent. The composition for killing the mites can effectively kill the mites in the environment and lowers harm to human bodies, or can be used as a food antiseptic to effectively resist putrefaction. The invention further provides a skin care composition and an oral cavity health composition, both comprising the trans-cinnamaldehyde.

Description

The composition that contains trans-cinnamic aldehyde
Technical field
The present invention relates to a kind of miticide composition that contains trans-cinnamic aldehyde, skin care compositions and oral care composition.
Background technology
Acarid belongs to arthropods, is the miniature insect that a kind of naked eyes are difficult for seeing, kind is a lot, finds that at present the acarid of living in room has more than 40 to plant.Modally comprise that dirt mite, flour mite, wriggle mite, itch mite etc. are all important pests common in room, the health of human body is produced to greatly harm.
Dirt mite is to occupy indoor distribution the most extensive, and they are distributed in carpet, curtain, sofa, down toy, bed clothes, cushion, mattress and pillow etc. and locate to grow, and consider to be worth doing as food take people's sweat, secretion, exuviae, and reproduction speed is exceedingly fast.Corpse, secretion and the excreta of dirt mite be all can be pathogenic anaphylactogen.Dirt mite can be along with people's activity, as the folded dust of being kicked up in, cleaning of making the bed etc. flies in the air, is inhaled in lung.At this moment, allergic constitution person will produce the allergic diseases such as allergic asthma, bronchitis, ephritis, allergic rhinitis and allergic dermatitis.Flour mite mainly resides in food, and human body can cause diarrhoea after using, become thin and the illness such as anaemia.The mite main parasitic of wriggling is in people's hair follicle and sebaceous glands, as places such as nose, ear, scalp, shirtfront, back, ducts.The existence of mite of wriggling can be stopped up skin pore, and destroys pilosebaceous follicle, causes the skin problems such as pore is thick, pachylosis, acne, acne, heavy develop into chronic skin disease, as acne rosacea.Itch mite parasitizes people and mammiferous skin surface, and its activity, swallowing all can chafe with excreta, and night is more violent, so that patient scratches skin and secondary bacterium infects, and running sore, folliculitis or furuncle occur.
Summary of the invention
In view of this, be necessary to provide a kind of composition that can kill mite.
A kind of miticide composition, it contains trans-cinnamic aldehyde, surfactant, solvent, and wherein the quality percentage composition of trans-cinnamic aldehyde is 0.0084%-0.268%, and the quality percentage composition of surfactant is 0.5%-2%.
This miticide composition can effectively kill the acarid in environment, reduces the harm that human body is caused; Or this miticide composition can be used as food preservative use, can be effectively anticorrosion.
A kind of skin care compositions, it contains trans-cinnamic aldehyde, salicylic acid, curcumin, solvent, in said composition, the quality percentage composition of trans-cinnamic aldehyde is 0.0084%-0.268%, and salicylic quality percentage composition is 0.5%-3%, and the quality percentage composition of curcumin is 0.1%-0.2%.
This skin care compositions can be used for the acne that mite infection causes, the treatment of whelk, and effect is remarkable.
A kind of oral care composition, it contains trans-cinnamic aldehyde, polyvinyl acetate, solvent, and wherein in said composition, the concentration of trans-cinnamic aldehyde is 0.008-0.256mg/ml, and the quality percentage composition of polyvinyl acetate is 2%-10%.
This oral care composition can effectively keep the pure and fresh of oral cavity and promote the healing of canker sore.
Embodiment
Trans-cinnamic aldehyde is to have strong canellaceous weak yellow liquid, and it can by indigenous cinnamon bark or the extraction of other cinnamon obtains or chemosynthesis makes.The molecular formula of trans-cinnamic aldehyde is C 9h 8o, molecular weight is 132.16g/mol, and density is 1.05g/ml, and fusing point is-7.5 ℃, and boiling point is 248 ℃, water insoluble, is dissolved in ethanol and ether etc.The structural formula of trans-cinnamic aldehyde is:
Figure BDA0000414403660000021
Trans-cinnamic aldehyde has antibacterial activity, antibiont film activity, and acaricidal activity, kills mosquito activity, antipathogen activity, anti-inflammatory activity, anti-red fire ant activity, anti-hyperuricemia activity etc.
A kind of miticide composition, it is mainly in order to kill the acarid in environment or to use as food preservative.This miticide composition contains trans-cinnamic aldehyde, surfactant (poly-mountain multitude's ester 80), solvent (distilled water).In said composition, the quality percentage composition of trans-cinnamic aldehyde is 0.0084%-0.268%, and the quality percentage composition of surfactant is 0.5%-2%.
In this miticide composition, also alternative is added glycerine, in order to increase the viscosity of composition.The quality percentage composition of this glycerine is 5%-10%.
In this miticide composition, also alternative is added jamaicin, in order to the antibiotic and sterilizing effect of further enhancing composition.The quality percentage composition of this jamaicin is 0.0011%-0.003%.
In addition, in this miticide composition, also alternative is added at least one in salicylic acid and curcumin.Wherein, salicylic acid plays effect of anti-inflammatory, and salicylic quality percentage composition is 0.5%-3%; Curcumin plays oxidation resistant effect, and the quality percentage composition of curcumin is 0.001-0.002%.
Below by embodiment, the present invention is specifically described.
Embodiment 1-3
Join three kinds of miticide compositions of the recipe configuration embodiment 1-3 of form below.Be specially following each component is uniformly mixed.
Table one
Figure BDA0000414403660000031
The miticide composition that embodiment 1-3 makes can effectively kill the acarid in environment, reduces the harm (as allergy) that human body is caused.
A kind of skin care compositions, it is mainly used in the treatment of all kinds of whelks that Propiobacterium infects or acarid is bred and cause.This skin care compositions contains trans-cinnamic aldehyde, salicylic acid, curcumin, solvent (distilled water).In said composition, the quality percentage composition of trans-cinnamic aldehyde is 0.0084%-0.268%, and salicylic quality percentage composition is 0.5%-3%, and the quality percentage composition of curcumin is 0.1%-0.2%.
In this skin care compositions, also alternative is added glycerine, in order to increase the viscosity of composition.The quality percentage composition of this glycerine is 5%-10%.
In this miticide composition, also alternative is added jamaicin, in order to the antibiotic and sterilizing effect of further enhancing composition.The quality percentage composition of this jamaicin is 0.11%-0.3%.
In addition, in this miticide composition, also alternative is added at least one in carbomer, Cobastab, ethanol, reed fragrant plant glue, hyaluronic acid and triethanolamine.Wherein, carbomer plays effect of gel, and the quality percentage composition of carbomer is less than or equal to 2% for being greater than 0; The quality percentage composition of ethanol is 2%-8%; Reed fragrant plant glue plays moisture-keeping function, and plays the rheological behavior of improving composition, and the quality percentage composition of reed fragrant plant glue is 0.5%-5%; Hyaluronic acid and Cobastab play effect of nourishes rough skin, and wherein hyaluronic quality percentage composition is 0.5%-1%, and the quality percentage composition of Cobastab is less than or equal to 0.002% for being greater than 0; Triethanolamine plays effect of pH adjusting agent, in order to regulate the pH to 6-8 of composition.
Below by embodiment, the present invention is specifically described.
Embodiment 4-6
Join three kinds of skin care compositionss of the recipe configuration embodiment 4-6 of form below.Be specially after first salicylic acid, jamaicin, curcumin proportionally being dissolved with distilled water and add carbomer again, to 6-8, finally add trans-cinnamic aldehyde with triethanolamine fine setting pH value of solution, formation gel stirs.
Table two
Project Embodiment 4 Embodiment 5 Embodiment 6
Trans-cinnamic aldehyde 0.0084% 0.168% 0.268%
Salicylic acid 0.5% 2% 3%
Jamaicin 0.11% 0.22% 0.3%
Curcumin 0.1% 0.15% 0.2%
Carbomer 1% 1.5% 2.0%
Triethanolamine In right amount In right amount In right amount
Distilled water Surplus Surplus Surplus
The skin care compositions that embodiment 4-6 makes can be used for the acne that mite infection causes, the treatment of whelk, and effect is remarkable.
A kind of oral care composition, it is mainly in order to the pure and fresh of effective maintenance oral cavity and promote the healing of canker sore.This oral care composition contains trans-cinnamic aldehyde, polyvinyl acetate (degree of polymerization is 200~700), solvent (distilled water).In said composition, the concentration of trans-cinnamic aldehyde is that quality percentage composition is 0.0084%-0.268%, and the quality percentage composition of polyvinyl acetate is 2%-10%.
That this trans-cinnamic aldehyde plays is antibacterial, promote the effect of canker sore healing.
Polyvinyl acetate, as polymer, for the basic colloid of composition, plays solid effect.
In this skin care compositions, also alternative is added at least one in xylitol, dibutyl hydroxy toluene (BHT), flavorant.Wherein, xylitol is as the flavor enhancement of composition, and its quality percentage composition is 8%-15%; Dibutyl hydroxy toluene (BHT) is as the antioxidant of composition, and its quality percentage composition is less than or equal to 0.01% for being greater than 0; The quality percentage composition of flavorant is 0.001%-0.01%.
Below by embodiment, the present invention is specifically described.
Embodiment 7-9
Join three kinds of oral care compositions of the recipe configuration embodiment 7-9 of form below.Be specially following each component is uniformly mixed.
Table three
Figure BDA0000414403660000051
Three kinds of oral care compositions of embodiment 7-9 can effectively keep the pure and fresh of oral cavity and promote the healing of canker sore.
In addition, those skilled in the art also can make various modifications, interpolation and the replacement in other form and details in the claims in the present invention scope of disclosure and spirit.Certainly, the variations such as various modifications, interpolation and the replacement that these make according to spirit of the present invention, within all should being included in the present invention's scope required for protection.

Claims (14)

1. a miticide composition, it is characterized in that: this miticide composition contains trans-cinnamic aldehyde, surfactant, solvent, this surfactant is poly-mountain multitude's ester 80, and wherein the quality percentage composition of trans-cinnamic aldehyde is 0.0084%-0.268%, and the quality percentage composition of surfactant is 0.5%-2%.
2. miticide composition as claimed in claim 1, is characterized in that: this solvent is distilled water.
3. miticide composition as claimed in claim 1, is characterized in that: in this miticide composition, be also added with at least one in glycerine, jamaicin, salicylic acid and curcumin.
4. miticide composition as claimed in claim 3, it is characterized in that: the quality percentage composition of this glycerine is 5%-10%, the quality percentage composition of jamaicin is 0.0011%-0.003%, and salicylic quality percentage composition is 0.5%-3%, and the quality percentage composition of curcumin is 0.001-0.002%.
5. the miticide composition as described in claim 1-4 any one, is characterized in that: this miticide composition is in order to kill acarid in environment or as food preservative.
6. a skin care compositions, it is characterized in that: this skin care compositions contains trans-cinnamic aldehyde, salicylic acid, curcumin, solvent, in said composition, the quality percentage composition of trans-cinnamic aldehyde is 0.0084%-0.268%, salicylic quality percentage composition is 0.5%-3%, and the quality percentage composition of curcumin is 0.1%-0.2%.
7. skin care compositions as claimed in claim 6, is characterized in that: this solvent is distilled water.
8. skin care compositions as claimed in claim 6, is characterized in that: in this miticide composition, be added with at least one in glycerine, jamaicin, carbomer, Cobastab, ethanol, reed fragrant plant glue, hyaluronic acid and triethanolamine.
9. skin care compositions as claimed in claim 8, it is characterized in that: the quality percentage composition of this glycerine is 5%-10%, the quality percentage composition of this jamaicin is 0.11%-0.3%, the quality percentage composition of carbomer is less than or equal to 2% for being greater than 0, the quality percentage composition of ethanol is 2%-8%, the quality percentage composition of reed fragrant plant glue is 0.5%-5%, hyaluronic quality percentage composition is 0.5%-1%, the quality percentage composition of Cobastab is less than or equal to 0.002% for being greater than 0, and the consumption of triethanolamine reaches the pH to 6-8 that regulates composition.
10. an oral care composition, it is characterized in that: this oral care composition contains trans-cinnamic aldehyde, polyvinyl acetate, solvent, wherein in said composition, the concentration of trans-cinnamic aldehyde is 0.0084%-0.268%, and the quality percentage composition of polyvinyl acetate is 2%-10%.
11. oral care compositions as claimed in claim 10, is characterized in that: this solvent is distilled water.
12. oral care compositions as claimed in claim 10, is characterized in that: the degree of polymerization of this polyvinyl acetate is 200-700.
13. oral care compositions as claimed in claim 10, is characterized in that: in this skin care compositions, be also added with at least one in xylitol, dibutyl hydroxy toluene, flavorant.
14. oral care compositions as claimed in claim 13, it is characterized in that: the quality percentage composition of xylitol is 8%-15%, the quality percentage composition of dibutyl hydroxy toluene is less than or equal to 0.01% for being greater than 0, and the quality percentage composition of flavorant is 0.001%-0.01%.
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Cited By (4)

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CN108478478A (en) * 2018-03-09 2018-09-04 佛山市三水区嘉华化学研究院(普通合伙) A kind of hydrogel microcapsule and its application in preparing cosmetics
CN109221207A (en) * 2018-09-04 2019-01-18 徐州光环新能源科技有限公司 A kind of indoor flower pesticide and preparation method thereof
CN113491685A (en) * 2021-09-09 2021-10-12 广东工业大学 Composition for inhibiting macrophage activation and application thereof in preparation of anti-inflammatory product
CN114096235A (en) * 2020-02-21 2022-02-25 弗门尼舍有限公司 Antimicrobial compositions

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108478478A (en) * 2018-03-09 2018-09-04 佛山市三水区嘉华化学研究院(普通合伙) A kind of hydrogel microcapsule and its application in preparing cosmetics
CN109221207A (en) * 2018-09-04 2019-01-18 徐州光环新能源科技有限公司 A kind of indoor flower pesticide and preparation method thereof
CN114096235A (en) * 2020-02-21 2022-02-25 弗门尼舍有限公司 Antimicrobial compositions
CN113491685A (en) * 2021-09-09 2021-10-12 广东工业大学 Composition for inhibiting macrophage activation and application thereof in preparation of anti-inflammatory product
CN113491685B (en) * 2021-09-09 2021-12-10 广东工业大学 Composition for inhibiting macrophage activation and application thereof in preparation of anti-inflammatory product

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Address after: 518057 research building C411, Research Institute of Tsinghua University, Shenzhen, Nanshan District, Guangdong

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