CN103751407A - 一种治疗风寒外袭证型三叉神经痛的中药 - Google Patents
一种治疗风寒外袭证型三叉神经痛的中药 Download PDFInfo
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Abstract
本发明公开了一种治疗风寒外袭证型三叉神经痛的中药，其特征是由下列重量配比的药材制成的：石苇40份、葛根30份、元参15份、荆芥穗15份、赤芍20份、勾藤20份、苍耳子20份、薄荷10份、甘草15份、全蝎10份、蜈蚣8份。本发明所制成的中药具有祛风散寒、活血化瘀、通络止痛的功效，能有效治疗风寒外袭证型三叉神经痛，五年来，通过对40名患者的使用表明，有效率达92%，愈后不再复发。
Description
技术领域
本发明涉及一种中药，特别是一种用于治疗风寒外袭证型三叉神经痛的中药。
背景技术
三叉神经痛是指发生在面部三叉神经分布区域内的剧烈疼痛，痛如放电、刀割样的疼痛症状、常人难以忍受的神经性疾病。发病率高，年龄多在40岁以后，女多于男。疼痛发作绝大多数有明显的诱发因素，少数病例无诱发因素即可疼痛发作。三叉神经痛扳机点多发生在上、下唇，鼻翼，鼻唇沟，牙龈，颊部，口角，舌，眉，胡须等处。常见的诱发因素包括咀嚼运动、刷牙、洗脸、剃须、说话、打呵欠、面部机械刺激、张嘴、笑、舌头活动、进食、饮水、风、声、光刺激等都会导致阵痛，阵发性时的剧烈疼痛，历时数秒或数分钟，病程越长疼痛时间越长，疼痛呈周期性发作，发作间歇期同正常人一样。
治疗方法分为无创和有创治疗方法。无创治疗方法包括药物治疗（西药疗法、中药疗法）中医中药针灸疗法、理疗等。有创治疗方法如：中医穴位埋线疗法、封闭疗法、阻滞疗法、射频热凝疗法、周围神经撕脱术、球囊压迫法、微血管减压术、伽玛刀治疗等。有创治疗方法主要是使该神经分布区域内感觉丧失，从而达到止痛的目的。药物疗法中的西药一般采用卡马西平、苯妥英钠、根痛平等，只是暂时止痛，不能根治，治愈率较低，中药疗法是安全有效的治疗方法，目前有多种用于治疗三叉神经痛的中药，但大多数中药存在着疗效较差，治愈低的缺陷，而且还没有一种专用于治疗风寒外袭证型三叉神经痛的中药。
发明内容
本发明的目的是想提供一种治疗风寒外袭证型三叉神经痛的中药，采用该中药治疗风寒外袭证型三叉神经痛，治疗效果好，治愈率高。
为实现本发明的上述目的所采用的技术方案是：一种治疗风寒外袭证型三叉神经痛的中药，其特征是由下列重量配比的药材制成的：
石苇40份、葛根30份、元参15份、荆芥穗15份、赤芍20份、勾藤20份、苍耳子20份、薄荷10份、甘草15份、全蝎10份、蜈蚣8份。
本发明上述配方中各药材的来源及功能主治如下：
石苇【来源】为水龙骨科植物石韦，庐山石韦、毡毛石韦、有柄石韦、北京石韦或西南石韦的叶。【性味】苦甘，凉。【归经】入肺、膀胱经。【功能主治】利水通淋，清肺泄热。治淋痛，尿血，尿路结石，肾炎，崩漏，痢疾，肺热咳嗽，慢性气管炎，金疮，痈疽。
葛根【来源】 本品为豆科植物野葛Pueraria lobata （Willd.）Ohwi或甘葛藤Pueraria thomsonii Benth.的干燥根。【性味】 甘、辛，凉。【归经】 归脾、胃经。【功能主治】 解肌退热，生津，透疹，升阳止泻。用于外感发热头痛、项背强痛，口渴，消渴，麻疹不透，热痢，泄泻；高血压颈项强痛。
元参【来源】为玄参科多年生草本植物玄参的根。【性味】味苦、咸，气微寒，无毒。【归经】入肺、肾、胃三经。【功能主治】清热凉血、养阴清热、泻火解毒、软坚散结。用于热病伤阴、舌绛烦渴、温毒发斑、津伤便秘、骨蒸劳嗽、目赤、咽痛、瘰疬、白喉、痈肿疮毒。
荆芥穗【来源】本品为唇形科植物荆芥 Schizonepeta tenuifolia Briq. 的干燥地上部分。【性味】味辛，性微温。【归经】归肺、肝经。【功能主治】解表散风，透疹。用于感冒，头痛，麻疹，风疹，疮疡初起。
赤芍【来源】 本品为毛茛科植物芍药Paeonia lactiflora Pall.或川赤芍Paeonia veitchii Lynch 的干燥根。【性味】 苦，微寒。【归经】 归肝经。【功能主治】 清热凉血，散瘀止痛。用于温毒发斑，吐血衄血，目赤肿痛，肝郁胁痛，经闭痛经，症瘕腹痛，跌扑损伤，痈肿疮疡。
勾藤【来源】 本品为茜草科植物钩藤Uncaria rhynch0phylla （Miq.） Jacks.、大叶钩藤 Uncaria macrophylla Wall.、毛钩藤Uncaria hirsuta Havil. 、华钩藤Uncaria sinensis （Oliv.）Havil. 或无柄果钩藤Uncaria sessilifructus Roxb. 的干燥带钩茎枝。【性味】 甘，凉。【归经】 归肝、心包经。【功能主治】 清热平肝，息风定惊。用于头痛眩晕，感冒夹惊，惊痫抽搐，妊娠子痫；高血压。
苍耳子【来源】 本品为菊科植物苍耳Xanthium sibiricum Patr.的干燥成熟带总苞的果实。【性味】 辛、苦，温；有毒。【归经】 归肺经。【功能主治】散风除湿，通鼻窍。用于风寒头痛，鼻渊流涕，风疹瘙痒，湿痹拘挛。
薄荷【来源】 本品为唇形科薄荷属植物薄荷 Mentha haplocalyx Briq.的干燥地上部分。【性味】 辛，凉。【归经】 归肺、肝经。【功能主治】 宣散风热。清头目，透疹。用于风热感冒，风温初起，头痛，目赤，喉痹，口疮，风疹，麻疹，胸胁胀闷。
甘草【来源】 本品为豆科植物甘草 Glycyrrhiza uralensis Fisch.、胀果甘草 Glycyrrhiza inflata Bat. 或光果甘草 Glycyrrhiza glabra L. 的干燥根。【性味】 甘，平。【归经】 归心、肺、脾、胃经 。【功能主治】 补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
全蝎【来源】该品为钳蝎科动物东亚钳蝎（Buthus martensii Karsch） 的干燥体。【性味】辛、平，有毒。【归经】归肝经。【功能主治】息风镇痉，攻毒散结，通络止痛。用于小儿惊风，抽搐痉挛，中风口歪，半身不遂，破伤风，风湿顽痹，偏正头痛，疮疡，瘰疬。
蜈蚣【来源】 本品为蜈蚣科动物少棘巨蜈蚣Scolopendra subspinipes mutilans L. Koch的干燥体。【性味】 辛，温；有毒。【归经】 归肝经。【功能主治】 息风镇痉，功毒散结，通络止痛。用于小儿惊风，抽搐痉挛，中风口歪，半身不遂，破伤风，风湿顽痹，疮疡，瘰疬，毒蛇咬伤。
中医学认为，三叉神经痛属“头痛”、“偏头痛”、“面痛”等范畴。
风寒侵犯阳明，风养升发易犯头面。寒邪使阳气受损，故恶寒喜暖，寒性凝滞，可致气血闭塞而痛。寒邪犯脑，搏与正气，郁久伤阳，血脉受引，致经络阻滞不通而痛。症状为阵发性面颊乃额头抽掣疼痛，许多数人有刀割样、火烧样疼痛，遇风寒加重，常牵及牙痛，大多数疼痛持续数秒至数分钟，一般为1～5分钟，个别病例疼痛可持续半小时以上，发作间歇期，疼痛可消失，间歇期随病情的进展而缩短，一般为数十分钟至数小时不等，重者可每分钟内都有发作，白天发作多，晚上发作少，也可日夜不停发作。患者苔薄白，脉浮弦。本病因由风寒外袭，寒凝血滞，阻塞面络，故治当以祛风、散寒、通络为主，本发明采用合适的药材及其配比，各药物之间相互配合，协同作用，所制成的中药具有祛风散寒、活血化瘀、通络止痛的功效，能有效治疗风寒外袭证型三叉神经痛，五年来，通过对40名患者的使用表明，有效率达92%，愈后不再复发。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2008年3月-2013年4月间共收集了80例风寒外袭证型三叉神经痛门诊患者，其中，男30例，女50例，年龄39-58岁，病情4-18个月。随机分为：治疗组40例，对照组40例。两组年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1对照组服用卡马西平，按照说明书服用。疗程20天。
2.2治疗组口服本发明按照具体实施例1制得的胶囊，早、中、晚各一次。疗程20天。
3、疗效标准及治疗结果
3.1疗效标准：
痊愈：治疗风寒外袭证型三叉神经痛的临床症状全部消失。好转：治疗风寒外袭证型三叉神经痛的临床症状减轻，病情得到控制。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率（%） |
| 治疗组 | 40 | 19 | 17 | 4 | 92% |
| 对照组 | 40 | 6 | 18 | 16 | 60% |
由此可见，采用本发明的组方制得的药物能够安全有效治疗风寒外袭证型三叉神经痛。
具体实施方式
为了更好地理解与实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取石苇40克、葛根30克、元参15克、荆芥穗15克、赤芍20克、勾藤20克、苍耳子20克、薄荷10克、甘草15克、全蝎10克、蜈蚣8克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗风寒外袭证型三叉神经痛。口服，每日分早、中、晚三次服用。
具体实施例2
称取石苇40克、葛根30克、元参15克、荆芥穗15克、赤芍20克、勾藤20克、苍耳子20克、薄荷10克、甘草15克、全蝎10克、蜈蚣8克，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常成人1天用量的散剂。
用于治疗风寒外袭证型三叉神经痛。口服，每日分早、中、晚三次服用。
具体实施例3
称取石苇40克、葛根30克、元参15克、荆芥穗15克、赤芍20克、勾藤20克、苍耳子20克、薄荷10克、甘草15克、全蝎10克、蜈蚣8克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，按照本领域常规工艺制粒，包装，即得符合正常成人1天用量的颗粒剂。
用于治疗风寒外袭证型三叉神经痛。口服，每日分早、中、晚三次服用。
Claims (1)
1.一种治疗风寒外袭证型三叉神经痛的中药，其特征是由下列重量配比的药材制成的：石苇40份、葛根30份、元参15份、荆芥穗15份、赤芍20份、勾藤20份、苍耳子20份、薄荷10份、甘草15份、全蝎10份、蜈蚣8份。
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| CN102309617A (zh) * | 2010-06-30 | 2012-01-11 | 兰圣国 | 一种治疗三叉神经痛的中药汤剂 |
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| CN102872443A (zh) * | 2012-10-28 | 2013-01-16 | 牛健坤 | 一种治疗偏头痛的药物及其制备方法 |
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| CN102309617A (zh) * | 2010-06-30 | 2012-01-11 | 兰圣国 | 一种治疗三叉神经痛的中药汤剂 |
| CN102861213A (zh) * | 2011-07-08 | 2013-01-09 | 贺玉清 | 一种治疗阴虚阳亢所致三叉神经痛的中药方 |
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