CN103585511B - 一种治疗肝郁型发热的中药 - Google Patents
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Abstract
本发明公开了一种治疗肝郁型发热的中药，其特征是由下列重量配比的药材制成的：柴胡10份、香附10份、佛手10份、白芍10份、当归10份、白术10份、茯苓10份、牡丹皮10份、栀子10份、白薇10份、夜交藤10份、谷芽10份、甘草10份。本发明采用合适的药材及其配比，各药物之间相互配合，协同作用，所制成的中药具有疏肝理气、清肝泻火、清热化瘀的功效，能有效治疗因肝郁而致的发热症，自2009年以来，通过对100名肝郁发热病患者的使用表明，有效率达96%。
Description
技术领域
本发明涉及一种中药，特别是一种用于治疗肝郁型发热的中药。
背景技术
发热是指致热原直接作用于体温调节中枢、体温中枢功能紊乱或各种原因引起的产热过多、散热减少，导致体温升高超过正常范围的情形。通常体温高出正常标准，或自有身热不适的感觉。发热原因，分为外感、内伤两类。外感发热，因感受六淫之邪及疫疠之气所致；内伤发热，多由饮食劳倦或七情变化，导致阴阳失调，气血虚衰所致。外感发热多实，见于感冒、伤寒、温病、瘟疫等病证；内伤多虚，有阴虚发热、阳虚发热、血虚发热、气虚发热、虚劳发热、阳浮发热、失血发热、肝郁发热等。目前，治疗发热的药物有许多种，但对症治疗的专用药用不是很多，目前还没有一种针对肝郁发热而治疗的药物。
发明内容
本发明的目的在于提供一种用于治疗肝郁型发热的中药，通过采用合适的药材及其配比达到安全有效的治疗肝郁型发热的目的。
为实现本发明的上述目的所采用的技术方案是：一种治疗肝郁型发热的中药，其特征是由下列重量配比的药材制成的：
柴胡10份、香附10份、佛手10份、白芍10份、当归10份、白术10份、茯苓10份、牡丹皮10份、栀子10份、白薇10份、夜交藤10份、谷芽10份、甘草10份。
本发明配方中各药材的功能主治如下：
柴胡【来源】本品为伞形科植物柴胡BupleurumchinenseDC.或狭叶柴胡BupleurumscorzonerifoliumWilld.的干燥根。【性味】苦，微寒。【归经】归肝、胆经。【功能主治】和解表里，疏肝，升阳。用于感冒发热，寒热往来，胸胁胀痛，月经不调，子官脱垂，脱肛。
香附【来源】本品为莎草科植物莎草CyperusrotundusL.的干燥根茎。【性味】辛、微苦、微甘，平。【归经】归肝、脾、三焦经。【功能主治】行气解郁，调经止痛。用于肝郁气滞，胸、胁、脘腹胀痛，消化不良，胸脘痞闷，寒疝腹痛，乳房胀痛，月经不调，经闭痛经。
佛手【来源】本品为芸香科柑橘属植物佛手CitrusmedicaL.var.sarcodactylisSwingle的干燥果实。【性味】辛、苦、酸，温。【归经】归肝、脾、肺经。【功能主治】舒肝理气，和胃止痛。用于肝胃气滞，胸胁胀痛，胃脘痞满，食少呕吐。
白芍【来源】本品为毛茛科植物芍药PaeonialactifloraPall.的干燥根。【性味】苦、酸，微寒。【归经】归肝、脾经。【功能主治】平肝止痛，养血调经，敛阴止汗。用于头痛眩晕，胁痛，腹痛，四肢挛痛，血虚萎黄，月经不调，自汗，盗汗。
当归【来源】本品为伞形科植物当归Angelicasinensis（Oliv.）Diels的干燥根。【性味】甘、辛，温。【归经】归肝、心、脾经。【功能主治】补血活血，调经止痛，润肠通便。用于血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，肠燥便秘，风湿痹痛，跌扑损伤，痈疽疮疡。
白术【来源】本品为菊科植物白术AtractylodesmacrocephalaKoidz.的干燥根茎。【性味】苦、甘，温。【归经】归脾、胃经。【功能主治】健脾益气，燥湿利水，止汗，安胎。用于脾虚食少，腹胀泄泻，痰饮眩悸，水肿，自汗，胎动不安。土白术健脾，和胃，安胎。用于脾虚食少，泄泻便溏，胎动不安。
茯苓【来源】本品为多孔菌科真菌茯苓Poriacocos（Schw.）Wolf的干燥菌核。【性味】甘、淡，平。【归经】归心、肺、脾、肾经。【功能主治】利水渗湿，健脾宁心。用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠。
牡丹皮【来源】本品为毛茛科植物牡丹PaeoniasuffruticosaAndr.的干燥根皮。【性味】苦、辛，微寒。【归经】归心、肝、肾经。【功能主治】清热凉血，活血化瘀。用于温毒发斑，吐血衄血，夜热早凉，无汗骨蒸，经闭痛经，痈肿疮毒，跌扑伤痛。
栀子【来源】本品为茜草科植物栀子GardeniajasminoidesEllis的干燥成熟果实。【性味】苦，寒。【归经】归心、肺、三焦经。【功能主治】果实：泻火除烦，清热利尿，凉血解毒。用于热病心烦，黄疸尿赤，血淋涩痛，血热吐衄，目赤肿痛，火毒疮疡；外治扭挫伤痛。
白薇【来源】本品为萝藦科植物白薇CynanchumatratumBge。或蔓生白薇CynanchumversicolorBge。的干燥根及根茎。【性味】苦、咸，寒。【归经】归胃、肝、肾经。【功能主治】清热凉血，利尿通淋，解毒疗疮。用于温邪伤营发热，阴虚发热，骨蒸劳热，产后血虚发热，热淋，血淋，痈疽肿毒。
夜交藤【来源】为蓼科植物何首乌的藤茎或带叶藤茎。【性味】甘微苦，平。【归经】入心、肝经。【功能主治】养心，安神，通络，祛风。治失眠，劳伤，多汗，血虚身痛，痈疽，瘰疬，风疮疥癣。
谷芽【来源】本品为禾本科植物粟Setariaitalica（L.）Beauv.的成熟果实经发芽干燥而得。【性味】甘，温。【归经】归脾、胃经。
【功能主治】消食和中，健脾开胃。用于食积不消，腹胀口臭，脾胃虚弱，不饥食少。炒谷芽偏于消食，用于不饥食少。
甘草【来源】本品为豆科植物甘草GlycyrrhizauralensisFisch.、胀果甘草GlycyrrhizainflataBat.或光果甘草GlycyrrhizaglabraL.的干燥根。【性味】甘，平。【归经】归心、肺、脾、胃经。【功能主治】补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
肝郁发热,多因情志抑郁,肝气不能调达,气郁化火而发热,或因恼怒过度以致发热。肝郁发热的证候一般表现为：时觉身热，发热不甚，或午后低热，常随情绪波动而起伏，抑郁不欢，喜叹息，或烦躁易怒，或兼胸胁胀痛，口苦咽干，泛恶欲呕，或妇女月经不调，舌质淡红，舌苔薄黄，脉弦细数。一般是因情志不畅，肝失疏泄，肝气郁滞，郁久化热，故出现发热，或午后低热；因情志所伤，故发热随情绪波动而起伏；肝气郁结，疏泄失常，故抑郁不欢，胸胁胀痛；肝气郁结，则血行不畅，故见妇女月经不调；叹气则气机暂得舒畅，故喜叹息；肝火上扰心神，故烦躁易怒；肝火灼津，则口苦咽干；肝气犯胃，胃失和降，则泛恶欲呕；舌质淡红，舌苔薄黄，脉象弦细数，为肝郁化火之象。本发明采用合适的药材及其配比，各药物之间相互配合，协同作用，所制成的中药具有疏肝理气、清肝泻火、清热化瘀的功效，能有效治疗因肝郁而致的发热症，自2009年以来，通过对100名肝郁发热病患者的使用表明，有效率达96%。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年4月-2013年5月间共治疗了100例肝郁型发热症门诊患者，年龄40-63岁，其中，男39例，女61例，近期无发热病史，体温<37.3℃，服用复方阿司匹林等药治疗无效。服用本发明的药物，10天为一个疗程，早、中、晚三次服用，连服二个疗程。
2、治疗结果及疗效标准：治愈：发热消失且追踪3个月未见复发；好转：患者自觉发热较前明显减轻；无效：连续服药2个疗程，症状未见减轻。结果:治愈76例,好转20例,无效4例,总有效率96%。
3、治疗统计结果见表1。
表1两组疗效比较
| 性别 | 人数 | 痊愈 | 好转 | 无效 | 有效率（%） |
| 男 | 39 | 35 | 4 | 0 | 100 |
| 女 | 61 | 41 | 16 | 4 | 93 |
| 合计 | 100 | 76 | 20 | 4 | 96 |
由此可见，本发明制得的药物能够安全有效治疗肝郁型发热症。
具体实施方式
为了更好地理解与实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取柴胡10克、香附10克、佛手10克、白芍10克、当归10克、白术10克、茯苓10克、牡丹皮10克、栀子10克、白薇10克、夜交藤10克、谷芽10克、甘草10克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗肝郁型发热症。口服，每日分早、中、晚三次服用。
具体实施例2
称取柴胡10克、香附10克、佛手10克、白芍10克、当归10克、白术10克、茯苓10克、牡丹皮10克、栀子10克、白薇10克、夜交藤10克、谷芽10克、甘草10克，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常成人1天用量的散剂。
用于治疗肝郁型发热症。口服，每日分早、中、晚三次服用。
具体实施例3
称取柴胡10克、香附10克、佛手10克、白芍10克、当归10克、白术10克、茯苓10克、牡丹皮10克、栀子10克、白薇10克、夜交藤10克、谷芽10克、甘草10克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即得符合正常成人1天用量的颗粒剂。
用于治疗肝郁型发热症。口服，每日分早、中、晚三次服用。
Claims (1)
1.一种治疗肝郁型发热的中药，其特征是由下列重量配比的药材制成的：柴胡10份、香附10份、佛手10份、白芍10份、当归10份、白术10份、茯苓10份、牡丹皮10份、栀子10份、白薇10份、夜交藤10份、谷芽10份、甘草10份。
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