CN103750819B - The hypodermis inner sensor device of implant angle can be controlled - Google Patents
The hypodermis inner sensor device of implant angle can be controlled Download PDFInfo
- Publication number
- CN103750819B CN103750819B CN201310724053.3A CN201310724053A CN103750819B CN 103750819 B CN103750819 B CN 103750819B CN 201310724053 A CN201310724053 A CN 201310724053A CN 103750819 B CN103750819 B CN 103750819B
- Authority
- CN
- China
- Prior art keywords
- test section
- hypodermis
- flexible test
- contact site
- implant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention discloses a kind of hypodermis inner sensor device controlling implant angle, including fixing seat and implant block, described implant block be provided with hard needle tubing by mouth and and described fixing seat be rotatably connected.The hypodermis inner sensor device of the controlled implant angle of the present invention, enable to after implantating biological sensors implants in hypodermis easily, and adjusting the angle in implantating biological sensors implantation skin histology as required so that implantating biological sensors effective length in hypodermis is longer；Measure the Numerical accuracy arrived higher, and actual numerical value is relatively.
Description
Technical field
The present invention relates to technical field of medical instruments, the hypodermis inner sensor device of a kind of controlled implant angle used when quickly being implanted in skin by implantating biological sensors.
Background technology
The diagnosis and treatment of numerous disease need to obtain continuous print physiological parameter, such as body temperature, heart rate, blood pressure, blood oxygen, blood sugar etc..In these parameters, some parameter can directly use the physical methods, such as temperature, heart rate can in-vitro measurements at any time；But some parameter but cannot obtain from in-vitro measurements, it is exactly a prominent example that such as diabetic needs to monitor blood sugar, it is necessary to just can obtain from measurement blood or tissue fluid；The method measuring tissue fluid is continuous monitoring means available in reality; its advantage is need not to take a blood sample continuously or by sensor implantable intravascular; the apparatus carried as daily patient; do not introduce excessive risks such as infecting or lose blood; can effectively provide again required data, so having become as the important directions of clinical monitoring development.As a example by blood sugar test, along with significantly increasing of onset diabetes rate the most in recent years, blood sugar monitoring has been more and more requisite clinical means, the product being currently used for patient's self detecting blood sugar is mainly Peripheral blood glucose (finger tip blood) single measurement, but to type i diabetes or the type ii diabetes patient of use insulinization, individual other single measurement does not often reach the requirement controlling blood sugar.Need a method that continuous blood sugar can be provided to monitor, make patient know oneself blood glucose condition at any time, take measures in time, can symptom management most effectively, prevent complication, obtain higher quality of life.
The blood sugar that can be used in clinic at present monitors product continuously, the technical microsensor (Medtronic, Sheng Meidinuo, Abbott Laboratories, DexCom) that only hypodermis is implanted into that must verify to a certain extent, peripheral blood between these products patient to be leaned on oneself collection, measure blood glucose concentration value sensor is calibrated, be all not reaching to separate calibrations and the degree of reliable Quality Control.It is not the most reliable reference method that the inadequate natural endowment of this mode refers to that blood surveys blood sugar, and deviation range is relatively big, specifies it is to be only patient to provide one with reference to scope rather than the exact value that has quality assurance by clinic.Technology still can not provide the method that blood sugar surveyed by effective tissue fluid at present, therefore it is a transient mode having no idea with referring to that blood blood glucose meter measurement result carrys out calibrating tissue liquid sensor, therefore also limit further genralrlization and the application of subcutaneous dynamic monitoring product, additionally, known subcutaneous sensor technology is all to implant with fixed angle transdermal, hard sensor or with 90 degree of right angles in skin, or tilt and skin with a certain oblique angle, it is all to contact with organized layer in the way of hypodermis layer, its intrinsic drawback is only finite length or contact area hypodermis layer, it is unfavorable for obtaining high s/n ratio and background eliminates.
Summary of the invention
In place of it is an object of the invention to provide for the deficiencies in the prior art, a kind of hypodermis inner sensor device controlling implant angle is provided, in place of the deficiencies in the prior art can being overcome, it enables to implantating biological sensors and implants easily in hypodermis, implantating biological sensors can be adjusted simultaneously as required and implant the angle in skin histology so that implantating biological sensors effective length in hypodermis is longer；Measure the Numerical accuracy arrived higher, and actual numerical value is relatively, improve the efficiency that sensor is implanted.
In order to solve above-mentioned technical problem, technical scheme is as follows: can control the hypodermis inner sensor device of implant angle, including for the fixing seat fixing with skin and implant block, described implant block is provided with hard needle tubing and is rotatably connected by mouth and with described fixing seat.
The applicant finds after research repeatedly is test, the most present implantating biological sensors certainty of measurement and actual value have gap, requirement can not be fully met, it is because implantating biological sensors effective length in hypodermis shorter, can the live part of effective contact tissue liquid be after entering skin corium below the 3-5mm degree of depth, the biggest due to different people colony or health different parts or fat layer thickness variation again, fashionable at health diverse location perpendicular insertion, the degree of depth is just frequently encountered by, more than 6mm, the situation thrusting muscle and produce pain.So the hard sensor length of an actually vertical implantation can not be more than 6mm, otherwise pain will be produced in the position that muscle is abundant.
nullExisting implantating biological sensors is implanting skin when，It is usually with 90 °、The angle of 45 ° is implanted，This effective length allowing for implanting the implantating biological sensors in hypodermis is shorter，Under complicated fluid environment，Numerical value and the actual value difference measured are bigger，For this，Applicant develops the hypodermis inner sensor device of the controlled implant angle of the application that knows clearly，This pedestal is divided into the fixing seat and implant block being hinged，When in use，First fixing seat is fixed on skin，Then implant block is rotated，It is made to extrude skin，With fixing seat shape in an angle，This angle is according to the position implanting skin、The situations such as angle are determined，Then implantating biological sensors hard needle tubing is wrapped up，It is implanted in hypodermis，Implanting when，Hard needle tubing substantially becomes 180 ° of angles with fixing seat，Make implantating biological sensors with parallel with skin surface or connect subparallel mode and implant，The length that such mode enables in implantating biological sensors implantation hypodermis is not limited by skin thickness，Its effective length is longer，The result making detection is more accurate.
As preferably, described implant block and described fixing seat are provided with the opening portion and protuberance being rotatably connected so that described fixing seat that cooperate with described implant block.
As preferably, described implant block being hinged with guide holder, described guide holder is provided with guide chute and the hard barrel outlet communicated with described guide chute.
As preferably, also include the locking and fixing device for being fixed on described implant block by described guide holder, described locking and fixing device to include being arranged on described guide holder and described implant block cooperating latch segment and locking teeth.
As preferably, described latch segment is arranged on described guide holder two relative side, and described locking teeth is located on described implant block, and described locking teeth includes support plate and is fixed on the pawl on described support plate top.
As preferably, described implant block is provided with the mouth that holds for placing described guide holder, is provided with inclination elastic plate bottom described guide chute.
As preferably, setting mounting groove bottom described guide chute, described inclination elastic plate one end is fixed in described mounting groove, and the other end is free end and stretches out in the described mounting groove described guide chute of entrance.
As preferably, also include that sensor unit, described sensor unit include staying for fixing implantable sensor the sensor installation seat of skin outer portion, are plugged in described sensor installation seat and can be implanted by described implantable sensor half pin that the internal subpackage of skin wrap and and described half pin connects and described half pin can be driven after the implanted skin of described implantable sensor under external force from described sensor installation seat to the separation block extracted out outside skin.
Sensor installation assembly, when in use, biology sensor with stratiform, implanted device and can control the hypodermis inner sensor device of implant angle with the use of, biology sensor includes flexible implantation test section and testing circuit contact site, wherein, flexible test section of implanting is implanted in skin, testing circuit contact site is stayed outside skin, when in use, sensor unit is arranged on implanted device, then the spring force of compression spring in implanted device is utilized, sensor of the invention assembly is driven to advance, after reaching precalculated position, sensor installation assembly and implanted device are separated, half pin is implanted test section with flexibility and is implanted in skin, simultaneously, under the effect of extension spring, separation block is quickly return with half pin；Whole process is the rapidest, achieve quickly the implanting of biology sensor, quickly the exiting of half pin, in implantation process, patient does not keenly feel, implantation speed is fast, efficiency is high, effective, simultaneously, in that stay and that biology sensor is fixing sensor installation seat stays guide holder and be fixed in the hypodermis inner sensor device that can control implant angle, until having detected.
As preferably, described implant block and described fixing seat are provided with the opening portion and protuberance being rotatably connected so that described fixing seat that cooperate with described implant block.It is rotatably connected, can be to be the modes such as hinged, pivot joint.
As preferably, described half pin includes half straight tube and and the bending tube of described half straight tube connection with needle point；Described separation block is provided with the straight trough coordinated with described half straight tube and and the bending groove of described bending tube cooperation.
Long channel opening axially offered by half pin, with wrapping biological sensor, especially the flexible of biology sensor implants test section, and connect for the ease of half pin and sub-material seat, just it is provided with bending tube and the structure of bending groove, by half needle end part bending, put in bending groove, both facilitated, and be easy to again processing, also achieve the purpose of connection simultaneously.
As preferably, described sensor installation seat includes upper pedestal and the lower base being provided with contact installing hole, described upper pedestal, lower base are respectively equipped with circular groove, lower arc groove, described upper circular groove, lower arc groove constitute for described half pin pass through hole；Described upper pedestal and/or described lower base are provided with fixes groove with the described biology sensor communicated through hole.
Sensor installation seat is divided into two parts, it is simple to fix biology sensor and the grafting of half pin, can be bondd by glue between two parts, can also be spirally connected or engage, the setting of groove fixed by biology sensor so that fixing of biology sensor is more firm, and position is more accurate.
As preferably, between described upper pedestal and described lower base, it is provided with the locating convex block cooperated and location shrinkage pool.
Locating convex block and location shrinkage pool enable to upper pedestal and lower base accurate positioning, it is simple to install fixing.
As preferably, described sensor installation seat and described separation block end are provided with the hole, location and locating piece making described sensor installation seat and described separation block carry out positioning when connecting.
In actual use, for reducing volume, separation block and sensor installation seat fit together, and are installed in implanted device for the ease of whole sensor unit, are just provided with locating piece and matched hole, location.
As preferably, described sensor installation seat is provided with a pair bayonet socket.
The existence of bayonet socket, sensor installation seat can be connected with implanted device, ensure the fastness accurately and after installation of its position, will not depart from not working when, meanwhile, bayonet socket is arranged on side, again can be needs when, depart from rapidly with implanted device timely, it is ensured that the whole implantation process of biology sensor smooth.
As preferably, described sensor installation seat upper surface is provided with the first linear guide slot, and described separation block is provided with the second linear guide slot communicated with described first linear guide slot, and described first linear guide slot, the second linear guide slot are two.
The existence of first, second linear guide slot, coordinate with linear guides, make sensor installation seat carrying out biology sensor implantation when, can take the air line, position is not occurred to offset, it is ensured that biology sensor implantation position accurate, simultaneously, ensure separation block accurately, return timely, half pin is extracted.
As preferably, described fixing seat is provided with button cell.
As preferably, also include the upper cover being arranged on described fixing seat and described implant block, described on cover wireless signal transmitter be installed.
Upper cover will fix seat and implant block couples together, and both protection can be got up again, additionally it is possible within it arrange electric elements etc., and implantating biological sensors matches.The data that implantating biological sensors detects are spread out of by wireless signal transmitter wirelessly, receiver receive, and use wirelessly, it is not necessary to electric wire connects.
As preferably, described upper cover includes lid and the L-shaped extension board downwardly extended for a pair being arranged on described lid；Described fixing seat, implant block are provided with and described L-shaped extension board matches the first slot, the second slot.
As preferably, described fixing seat is provided with and is positioned at the elastic locking plate extended above described first slot and to described implant block direction, having gap between described elastic locking plate and described implant block lateral surface, its one end is fixed on described fixing seat, and the other end is free end.
The existence of elastic locking plate so that upper cover and fixing seat engage when, it can be inwardly described, it is simple to engaging, is flared out so that the connection after engaging is more firm after contraction.
As preferably, described fixing seat and described implant block lower surface are provided with for the adhesive plaster fixing with skin.
Adhesive plaster uses conventional medical proof fabric, can fixing seat and implant block be bonded and fixed on skin.
As preferably, described adhesive plaster is to be provided with the entirety of interrupted opening or for be separately positioned on two pieces on described fixing seat and described implant block at described fixing seat and described implant block intersection.
nullAs preferably，Described implantating biological sensors includes the blank electrode of sheet、The reference electrode of sheet、The working electrode of sheet and sheet to electrode，Described blank electrode includes the first flexible test section of the first electrical contact portion and elongated strip，Described reference electrode includes the second flexible test section of second circuit contact site and elongated strip，Described working electrode includes the 3rd flexible test section of tertiary circuit contact site and elongated strip，Described the 4th flexible test section that electrode is included the 4th electrical contact portion and elongated strip，Described blank electrode、Reference electrode、Working electrode and to electrode overlap after formed include the first electrical contact portion、Second circuit contact site、Tertiary circuit contact site、The testing circuit contact site in the 4th electrical contact portion and include the first flexible test section、Second flexible test section、3rd flexible test section、4th the flexible of flexible test section implants test section；Described first electrical contact portion, second circuit contact site, tertiary circuit contact site and the 4th electrical contact portion are equipped with electric contact, and after described first electrical contact portion, second circuit contact site, tertiary circuit contact site and the superposition of the 4th electrical contact portion form testing circuit contact site, each electric contact is exposed independent from.
nullThe applicant finds after research repeatedly and experiment，The environment that subcutaneous sensor works in hypodermis，It is discrepant under being with ideal conditions，Under ideal conditions, detection is all pure solution，There is no any interference，And in actually detected，With the presence of multiple foreign matter such as adipocytes in hypodermic tissue fluid，These existence can disturb the detection of sensor，For this，The special disposal background drift of the implantable sensor of the present invention and the rectification electrode of chemistry disruption，Namely blank electrode，Utilize blank electrode that time dependent background and random disturbances are corrected immediately，There is provided for signal processing and eliminate background and the variable of interference，So that the specificity of sensor signal and accuracy are more secure，Be conducive to obtaining high s/n ratio and background eliminates，And the function of reference electrode is as working electrode and blank electrode provide reference voltage current potential，Working electrode voltage is made to be maintained at effective oxidation reduction electro-dynamic potential，Working electrode is bio-sensing electrode，With bio-sensing layer on electrode surface，Analyzed molecule can be detected，And on electrode, form signal code，Closed loop current is provided for whole circuit to electrode，Form current loop.
Additionally, applicant have further found that, existing biology sensor has some to be based on hard material or hard substrate, hard material or the existence of hard substrate, make implanting hypodermis when, it produces bigger stimulation to hypodermis, first this can produce a sense of discomfort, people is made to have the existence of foreign body sensation, it is unfavorable for the long storage time of biology sensor, secondly, hard material or hard substrate are in use, can persistently stimulate hypodermis surrounding environment, hypodermis is changed, deviation normal condition, make to detect the numerical value obtained and actual difference is bigger, and be also a disadvantageous factor to biosensor organism compatibility.Therefore, biology sensor is made laminated structure by applicant, it is overlapped into one after each electrode is made sheet, overlapping described here, refer to the blank electrode of sheet, the reference electrode of sheet, the working electrode of sheet and sheet to electrode superposition after, secure bond is integral, glue can be used to bond, the mode of binding can also be used, or the mode of bookbinding, or the various ways such as it is mutually clamped, four electrode overlappings of laminated structure, sensor bulk can be reduced as far as possible, additionally, whole biology sensor or the part entering the interior detection of hypodermis are flexible, both combine and make the generation in tissue of whole biology sensor less persistently stimulate, it is greatly increased sensor senses real physiological environment and the degree of state, improve accuracy of detection, its measured value and actual value are more nearly.
As preferably, described blank electrode, reference electrode, working electrode and electrode is sequentially overlapped from top to bottom.
Using above combination above order to be overlapped, the numerical value detected and actual value are relatively.
As preferably, the described flexible structural strength implanting test section reduces to the end away from described testing circuit contact site gradually from the root being connected with described testing circuit contact site..
Gradually the reduction of structural strength, can be linear, it is also possible to be stair-stepping, such frame mode, during making flexible implantation test section away from root, thickness changes, and becomes to compare thinner, further reduces the stimulation to tissue, same, its thickness is during root, and pliability strengthens, it is possible to prevent fracture；Because along with moving closer to root, its stress is the most increasing, if sensor thickness is made unanimously, then thinner in order to avoid stimulate hypodermis to do, it is easy for fracture or crack occurs, especially near the place of root, its stress is bigger, stress is more concentrated, also fracture it is easier to, it is easier to that crack occurs, and these all can affect the certainty of measurement of sensor, if and select thicker thickness, then the biggest to hypodermic stimulation, also accuracy of detection can be affected, and use the mode of the technical program, i.e. reduce hypodermic stimulation, in turn ensure that structural strength, and then improve accuracy of detection.
As preferably, described first flexible test section, the second flexible test section, the 3rd flexible test section become big successively away from the end of described testing circuit contact site and the distance of described testing circuit contact site, and the described 3rd flexible test section, the 4th flexible test section are away from the end face flush of described testing circuit contact site.
As preferably, the described first flexible test section, the second flexible test section, the 3rd flexible test section and the 4th flexible test section become big successively away from the end of described testing circuit contact site and the distance of described testing circuit contact site.
As preferably, the described first flexible test section, the second flexible test section, the 3rd flexible test section and the 4th flexible test section width are equal；Described first electrical contact portion, second circuit contact site, tertiary circuit contact site and the 4th electrical contact portion width are equal.
Above-mentioned setting, it is simple to make and install, the volume simultaneously making whole biology sensor is the least, especially the volume of four flexible test sections most probably little.
As preferably, the length and width ratio of the described first flexible test section, the second flexible test section, the 3rd flexible test section and the 4th flexible test section is more than 10.
As preferably, the described first flexible test section, the second flexible test section, the 3rd flexible test section and the 4th flexible test section are cuboid.
As preferably, described first electrical contact portion, second circuit contact site, tertiary circuit contact site and the 4th electrical contact portion are cuboid.
A kind of method manufacturing implantating biological sensors；1. make sheet and there is the blank electrode substrate of electric contact, reference electrode substrate, working electrode substrate and to electrode base board；2. cut by the blank electrode substrate made, reference electrode substrate, working electrode substrate and after electrode base board is overlapped according to predefined procedure, form testing circuit contact site and flexible implant test section.
This manufacture method, the manufacture to each electrode, use integral planar technique, after producing four electrodes of sheet, then it is adhesively fixed, then cuts, its whole industrial process, technical maturity is high, is suitable for batch production, simple and reliable, the biology sensor manufactured, the most forward end of pliability is the best, and good biocompatibility is light to tissue stimulation.
The present invention has the beneficial effects that:
1) enable to implantating biological sensors implant in hypodermis easily, and adjust the angle in implantating biological sensors implantation skin histology as required so that implantating biological sensors effective length in hypodermis is longer；Measure the Numerical accuracy arrived higher, and actual numerical value is relatively, improve the efficiency that biology sensor is implanted；
2) by biology sensor assembly, so that implantable sensor is quickly implanted in hypodermis, and half pin quickly being exited, whole process is very rapid, and in implantation process, patient does not keenly feel, and it is high that efficiency implanted by biology sensor, implants effective.
3), after in implantable sensor implants hypodermis, the stimulation of generation is smaller, and foreign body sensation is little, and the data value detected and actual value are relatively.
Accompanying drawing explanation
The present invention is described further below in conjunction with the accompanying drawings:
Fig. 1 is the structural representation of one embodiment of the invention；
Fig. 2 is the three-dimensional exploded view of Fig. 1；
Fig. 3 is fixing seat and implant block connection diagram；
Fig. 4 is fixing seat and implant block, mounting seat and can control schematic diagram after the hypodermis inner sensor device of implant angle is installed；
Fig. 5 is the application schematic diagram of one embodiment of the invention；
Fig. 6 is the structural representation after sensor installation seat, half pin and separation block connect；
Fig. 7 is the exploded view of Fig. 6；
Fig. 8 sensor installation seat and guide holder connection diagram；
Fig. 9 is that Fig. 8 decomposes the schematic diagram come；
Figure 10 is sensor installation seat exploded view；
Figure 11 is the structure chart of implantable sensor；
Figure 12 is the three-dimensional exploded view of Figure 11；
Figure 13 is the stereogram of Figure 11.
In figure:
1, fixing seat, 101, protuberance, the 102, first slot, 103, elastic locking plate, 2, implant block, 201, opening portion, 202, mouth is held, the 203, second slot, 204-hard needle tubing passes through mouth, 205-protruding plate, 3, guide holder, 301, guide chute, 302, hard barrel outlet, 303, elastic plate is tilted, 304, mounting groove；4, locking and fixing device, 401, latch segment, 402, locking teeth, 5, button cell, 6, upper cover, 601, lid, 602, L-shaped extension board, 7, adhesive plaster, 8, implanted device；9, sensor unit, 901, sensor installation seat, 90101, contact installing hole, 90102, upper pedestal, 90103, lower base, 90104, upper circular groove, 90105, lower circular groove, 90106, through hole, 90107, sensor seating groove, 90108, locating convex block, 90109, location shrinkage pool, 90110, hole, location, 90111, bayonet socket, 90112, the first linear guide slot, 90113, tilt draw-in groove；902, half pin, 90201, half straight tube, 90202, bending tube, 903, separation block, 90301, straight trough, 90302, bending groove, 90303, locating piece, the 90304, second linear guide slot；1001, blank electrode, the 100101, first electrical contact portion, the 100102, first electrical contact portion, 1002, reference electrode, 100201, second circuit contact site, 100202, second circuit contact site, 100 3, working electrode, the 100301, tertiary circuit contact site, the 100302, the 3rd flexible test section, 1004, to electrode, 100401, the 4th electrical contact portion, the 100402, the 4th flexible test section, 1005, testing circuit contact site, 1006, flexible test section of implanting, 1007, electric contact.
Detailed description of the invention
The following stated is only presently preferred embodiments of the present invention, is not defined the scope of the present invention.
Embodiment, see accompanying drawing 1,2,3,4,5,6,7,8,9,10,11,12,13, the hypodermis inner sensor device of implant angle can be controlled, including the fixing seat 1 can fixed with skin and the implant block 2 can fixed with skin, hard needle tubing is offered by mouth 204, it is simple to hard needle tubing and implantating biological sensors pass through on implant block 2；Implant block and fixing seat are made up of the plastics of sheet, and for transparence, end fillet processes；Described implant block 2 and described fixing seat 1 are rotatably connected, can hinged, pivot joint etc., it would however also be possible to employ gemel connection, or use the material of easy bending to connect, such as rubber sheet, sheet of polyurethane etc. so that implant block 2 can rotate around fixing seat 1；nullFor this，Described implant block 2 and described fixing seat 1 are provided with the opening portion 201 and protuberance 101 being rotatably connected so that described fixing seat 2 that cooperate with described implant block 2，In the present embodiment，Described implant block 2 is provided with opening portion 201，Opening portion is arranged on the end of implant block，It caves inward，Form opening portion 201，Described fixing seat 1 is provided with the protuberance 101 stretching into described opening portion 201，Described protuberance 101 is hinged by rotating shaft and described opening portion 201，Rotating shaft is arranged on protuberance 101 two ends，Insert in the side of opening portion 201，Realization is articulated and connected，Certainly，Can also be in turn，A part is protruded above at implant block 2，A fixing seat depression part，Realization is articulated and connected，Or carry out hinged with articulated manner known to other，It is not described in detail in this，Implant block 2 and fixing seat 1 are hinged，Make carrying out implantating biological sensors implantation when，Angular adjustment can be carried out，Make implantating biological sensors to become 180 ° or approximately parallel mode to implant with the skin under fixing seat，Concrete angle determines according to actual conditions,Generally 170-180 °.
Upper cover 6 on described fixing seat 1 and described implant block 2, wireless signal transmitter is installed in upper cover 6, upper cover 6 uses hard material to make, on described fixing seat 1, button cell 5 is installed, it is used for providing power supply, described upper cover 6 to include lid 601 and the L-shaped extension board 602 downwardly extended for a pair being arranged on described lid 601；nullDescribed fixing seat 1、Implant block 2 is provided with the first slot 102 matched with described L-shaped extension board 602、Second slot 203，When upper cover covers on implant block and fixing seat when，L-shaped extension board 602 snaps in the first slot 102、In second slot 203，Described fixing seat 1 is provided with and is positioned at the elastic locking plate 103 extended above described first slot 102 and to described implant block 2 direction，Elastic locking plate 103 is a pair，It is arranged on 2 two sides of implant block，One end is fixed on implant block 2，The other end is free end，Gap is had between described elastic locking plate 103 and described implant block 2 lateral surface，It is fixed on skin for the ease of fixing seat 1 and implant block 2，Described fixing seat 1 and described implant block 2 lower surface are provided with for the adhesive plaster 7 fixing with skin，Described adhesive plaster 7 can be an entirety，Two pieces can also be divided into，Be one overall when，It is provided with interrupted opening at described fixing seat 1 and described implant block 2 intersection，It is easy to implant block 2 and fixing seat 1 rotates.
nullIn order to improve efficiency，We are provided with sensor unit，Including sensor installation seat 901、Half pin 902 and separation block 903，Sensor installation seat 901 is fixed for the end that implantable sensor is stayed skin,Implantating biological sensors is divided into two parts，One is to need to implant in skin the part carrying out detecting，Test section is implanted we term it flexible，One is to stay the part outside skin，Connect with other electric elements，The data of detection are sent，We are referred to as testing circuit contact site，Testing circuit contact site is fixed by sensor installation seat，Simultaneously，Half pin 902 is plugged in sensor installation seat 901，And implantable sensor can be implanted parts of skin namely flexible test section of implanting and wrap up by it，In actual work，Because being all first implantating biological sensors to be arranged on sensor installation seat，Make half pin 902 that implantating biological sensors is wrapped up again，Therefore，Whole flexible test section of implanting actually is wrapped up by half pin，Simultaneously，The portion envelops of testing circuit contact site is got up，Separation block 903 is connected with half pin 902，Because half pin 902 is plugged in sensor installation seat，After completing biology sensor is implanted skin，It can not be stayed in skin，Fall back on outside，Therefore，Just it is provided with the separation block 903 connected with half pin 902 end，It can drive half pin 902 quickly to extract out from sensor installation seat 901 and in skin under external force.
Half pin 902 is divided into two parts, a part is for wrapping biological sensor, a part is used for and separation block 903 connects, the part of wrapping biological sensor is to have the half straight tube 90201 of needle point, the part connected with separation block is to be arranged on the bending tube 90202 of half straight tube end, in order to connect with half pin 902, separation block 903 is provided with the straight trough 90301 coordinated with half straight tube 90201 and the bending groove 90302 coordinated with bending tube 90202, and straight trough 90301, bending groove 90302 are arranged on the upper surface of separation block 903.
Sensor installation seat 901 includes upper pedestal 90102 and lower base 90103, upper pedestal 90102, upper pedestal 90102 and lower base 90103 can be spirally connected fixing or be adhesively fixed, being provided with contact installing hole 90101 on upper pedestal 90102, it is used for installing electric contact and biology sensor contacts, and detection data is sent in electrical signal form, in present embodiment, contact installing hole 90101 is four, and guide holder is provided with open ports, in order to four contact installing holes expose and contact with upper cover；Upper pedestal 90102, lower base 90103 are provided with circular groove 90104, lower arc groove 90105, upper circular groove 90104, lower arc groove 90105 are symmetrical arranged, upper circular groove 90104, lower arc groove 90105 constitute for half pin 902 pass through hole 90106, have gap through hole 90106 and half pin；Upper pedestal 90102 and/or lower base 90103 are provided with and pass the biology sensor that hole 90106 communicates and fix groove 90107, biology sensor is fixed groove 90107 and can be arranged on lower base 90103, for rectangular channel, in present embodiment, it is divided into two parts, set up separately on upper and lower pedestal, naturally it is also possible to be provided separately within upper pedestal；For the ease of upper pedestal 90102 and the installation of lower base 90103, it is provided with the locating convex block 90108 cooperated and location shrinkage pool 90109 between, locating convex block 90108 is cuboid, it is arranged on upper pedestal lower surface, location shrinkage pool 90109 is also rectangle, arranges the upper surface of lower base 90103；Both cooperate, the location of lower base in realization, simultaneously, for the ease of being installed in implanted device, and quickly can separate with implanted device 8 needs when, sensor installation seat 901 is provided with a pair bayonet socket 90111 near the end sides of separation block 903, and bayonet socket 90111 is circular arc, is arranged on two opposite flanks of separation block 903 end；Coordinate with the claw of implanted device, additionally, the position of a pair bayonet socket can determine according to the actual requirements, such as, be arranged on centre position.
It not fixing connection between sensor installation seat 901 and separation block 903, can also there is no annexation, however, to ensure that the accurate and biology sensor implantation process of both positions is smooth, we are provided with hole 90110, location in the end of sensor installation seat 901, and separation block 903 is provided with and positions hole 90110 coordinates and locating piece 90303.Simultaneously, sensor installation seat 901 upper surface is provided with the first linear guide slot 90112, separation block 903 is provided with the second linear guide slot 90304 communicated with the first linear guide slot 90112, the linear guides of first linear guide slot the 90112, second linear guide slot 90,304 first linear guide slot 90112 and implanted device coordinates, what guarantee sensor installation seat and separation block were carried out in moving forward and backward is rectilinear movement, first linear guide slot the 90112, second linear guide slot 90304 is two, symmetrical setting.
nullImplantation for the ease of sensor，Also make that sensor is easier to be implanted in skin in the way of parallel with the skin under fixing seat，Described implant block 2 is hinged with guide holder 3，Described guide holder 3 is provided with guide chute 301 and the hard barrel outlet 302 communicated with described guide chute 301，Hard barrel outlet 302 and hard needle tubing are communicated by mouth 204，The when of use，Guide chute and sensor installation seat 901 match，Sensor installation seat 901 can be slided in guide chute，I.e. ensure that position is accurate，Be conducive to again quickly implanting，Simultaneously，Because guide holder is hinged on implant block，Guide holder and the angle of implant block can be adjusted according to practical situation，This arranges and is used in combination with implant block is hinged with fixing seat，Implantating biological sensors is carried out the regulation of implant angle，So，Said structure can either ensure the accurate of implantating biological sensors implantation position and improve the efficiency implanted，Make the implantating biological sensors can be convenient、Readily implant in hypodermis，Make the located subcutaneously in-house effective length of implantating biological sensors enough.
nullAfter sensor has been implanted，Sensor installation seat 901 and guide holder all can be stayed on pedestal，This time，Need to fix both，Prevent it from loosening the change causing implantating biological sensors position，Fix firstly the need of being directed to seat，For this，We are provided with the locking and fixing device 4 for being fixed on described implant block 2 by described guide holder 3，Locking and fixing device 4 is for the purpose of being directed to seat and being fixed on implant block 2，There is presently provided the structure of a kind of locking and fixing device 4，Described locking and fixing device 4 includes being arranged on cooperate on described guide holder 3 and described implant block 2 latch segment 401 and locking teeth 402，Described latch segment 401 is arranged on described guide holder 3 two relative side，Described locking teeth 402 is located on described implant block 2，Described locking teeth 402 includes support plate and is fixed on the pawl on described support plate top，Locking when，The power of latch segment acts on pawl side，Support plate below pawl slopes inwardly，It is flared out the most again，Realize the locking to latch segment；Certainly, described locking and fixing device 4 can also use fairly simple structure, is arranged on described guide holder 3 and described implant block 2 cooperate latch segment 401 and locking slot.
In addition, in order to ensure Detection results, it is provided with at described implant block 2 and holds mouth 202 for place described guide holder 3, inclination elastic plate 303 it is provided with bottom described guide chute 301, mounting groove 304 is set bottom described guide chute 301, described inclination elastic plate 303 one end is fixed in described mounting groove 304, the other end is free end and stretches out described mounting groove 304 and enter in described guide chute 301, the elastic clamping to sensor installation seat 901 is realized by tilting elastic plate 303, sensor installation seat 1 bottom surface is provided with and tilts the inclination draw-in groove 90113 that elastic plate 303 matches.And when using latch segment to lock groove as locking and fixing device 4 when, locking slot is arranged on and holds mouth 202 side, it is used for engaging the latch segment 401 being arranged on guide holder 3 side, when using locking teeth to lock block when, holding mouth to be provided with side and be provided with opening, locking teeth is arranged in the opening of side, holds mouth 202 bottom surface and is provided with protruding plate 205 in the end away from hard barrel outlet 302, it is used for sensor installation seat 901 carries out spacing and clamping, prevents it from loosening.
Implantating biological sensors 10, biology sensor is layer structure, including sheet blank electrode 1001, the reference electrode 1002 of sheet, the working electrode 1003 of sheet and sheet to electrode 1004, four electrodes are all cuboids, after superposition bonding after integral, the order of arrangement can be carried out, wherein according to the actual requirements, it is also preferred that the left be followed successively by blank electrode 1001, reference electrode 1002, working electrode 1003 and to electrode 1004 from top to bottom；nullDescribed blank electrode 1001 includes the first flexible test section 100102 of the first electrical contact portion 100101 and elongated strip，Described reference electrode 1002 includes the second flexible test section 100202 of second circuit contact site 100201 and elongated strip，Described working electrode 1003 includes the 3rd flexible test section 100302 of tertiary circuit contact site 100301 and elongated strip，Described the 4th flexible test section 100402 that electrode 1004 is included the 4th electrical contact portion 100401 and elongated strip，Described first flexible test section 100102、Second flexible test section 100202、Why 3rd flexible test section 100302 and the 4th flexible test section 100402 are elongated strips，It is to reduce the stimulation to subcutaneous tissue cell as far as possible，Its length and width ratio is more than 10，Length-width ratio is the bigger the better；And, for the ease of fabricating and obtain reasonable Detection results, the described first flexible test section 100102, second flexible test section of flexible test section the 100202, the 3rd 100302 and the 4th flexible test section 100402 are cuboid, and width is equal；Described first electrical contact portion 100101, second circuit contact site 100201, tertiary circuit contact site 100301 and the 4th electrical contact portion 100401 are cuboid, and width is equal.
Blank electrode 1001, reference electrode 1002, working electrode 1003 and to electrode 1004 superposition and formed after boning and include the first electrical contact portion 100101, second circuit contact site 100201, the testing circuit contact site 1005 in tertiary circuit contact site the 100301, the 4th electrical contact portion 100401 and include that the first the flexible of the flexible test section the 100202, the 3rd of flexible test section 100102, the second flexible test section 100402 of flexible test section the 100302, the 4th implants test section 1006；Flexible test section 1006 of implanting is implanted in hypodermis, detects, and it directly contacts with tissue fluid, and testing circuit contact site 1005 is then left outside, and is used for and external circuit connection, flexibility is implanted the data that test section 1006 plant quarantine measures and sends；It is analyzed contrast；nullFor the ease of connecting with external circuit，Described first electrical contact portion 100101、Second circuit contact site 100201、Tertiary circuit contact site 100301 and the 4th electrical contact portion 100401 are equipped with electric contact 1007，Thus there are four electric contacts，And when described first electrical contact portion 100101、Second circuit contact site 100201、After tertiary circuit contact site 100301 and the superposition of the 4th electrical contact portion 100401 form testing circuit contact site 1005，Each electric contact 1007 is exposed independent from，That is，A part is stretched out in second circuit contact site 100201 end being positioned under the first electrical contact portion 100101，So that arranging electric contact，Same，Tertiary circuit contact site 100301 end is compared second circuit contact site and is also stretched out a part，4th end, electrical contact portion compares tertiary circuit contact site and also stretches out a part，For arranging electric contact.
nullIn order to improve the accuracy of detection numerical value，Reduce foreign body sensation and reduce hypodermic stimulation，The described flexible structural strength implanting test section 1006 reduces to the end away from described testing circuit contact site 1005 gradually from the root being connected with described testing circuit contact site 1005，Gradually reducing can be linear reduction or stepped reduction，In the present embodiment，Use，Described first flexible test section 100102、Second flexible test section 100202、3rd flexible test section 100302 becomes big successively away from the end of described testing circuit contact site 1005 and the distance of described testing circuit contact site 1005，And described 3rd flexible test section 100302、4th flexible test section 100402 is away from the end flush of described testing circuit contact site 1005；It is the formation of three ladders between such four test sections.
In addition, the structure of accompanying drawing 13 can also be used, described first flexible test section 100102, the second flexible test section of flexible test section the 100202, the 3rd 100302 and the 4th flexible test section 100402 become big successively away from the end of described testing circuit contact site 1005 and the distance of described testing circuit contact site 1005, form four ladders between four test sections.
A kind of implantating biological sensors manufacture method, 1. makes sheet and has the blank electrode substrate of electric contact 1007, reference electrode substrate, working electrode substrate and to electrode base board；Blank electrode substrate, reference electrode substrate, working electrode substrate and to electrode base board now with blank electrode, reference electrode, working electrode and the difference of electrode is only in that shape, remaining is the most identical, 2. cut by the blank electrode substrate made, reference electrode substrate, working electrode substrate and after electrode base board is overlapped according to predefined procedure, form testing circuit contact site 1005 and flexible implant test section 1006.
Described above is only explanation of the invention, those of ordinary skill in the art's can completely is made to implement this programme, but it is not limitation of the present invention, the present embodiment can be made after reading this specification by those skilled in the art as required does not has the amendment of creative contribution, and these are all the most creative amendments.But as long as all being protected by Patent Law in scope of the presently claimed invention.
Claims (25)
1. can control the hypodermis inner sensor device of implant angle, it is characterised in that: including fixing seat (1) and implant block (2), described implant block (2) is provided with hard needle tubing to be passed through mouth (204) and is rotatably connected with described fixing seat (2)；Described implant block (2) and described fixing seat (1) are provided with the opening portion (201) and protuberance (101) being rotatably connected so that described fixing seat (2) and described implant block (2) that cooperate.
The hypodermis inner sensor device controlling implant angle the most according to claim 1, it is characterized in that: be hinged with guide holder (3) on described implant block (2), described guide holder (3) is provided with guide chute (301) and the hard barrel outlet (302) communicated with described guide chute (301).
The hypodermis inner sensor device controlling implant angle the most according to claim 2, it is characterised in that: also include the locking and fixing device (4) for being fixed on described implant block (2) by described guide holder (3)；Described locking and fixing device (4) includes being arranged on cooperate on described guide holder (3) and described implant block (2) latch segment (401) and locking teeth (402).
The hypodermis inner sensor device controlling implant angle the most according to claim 3, it is characterized in that: described latch segment (401) is arranged on described guide holder (3) two relative side, described locking teeth (402) is located on described implant block (2), and described locking teeth (402) includes support plate and is fixed on the pawl on described support plate top.
The hypodermis inner sensor device controlling implant angle the most according to claim 2, it is characterized in that: described implant block (2) is provided with and holds mouth (202) for place described guide holder (3), and described guide chute (301) bottom is provided with inclination elastic plate (303).
The hypodermis inner sensor device controlling implant angle the most according to claim 5, it is characterized in that: described guide chute (301) bottom sets mounting groove (304), in described inclination elastic plate (303) one end is fixed on described mounting groove (304), the other end is free end and stretches out described mounting groove (304) and enter in described guide chute (301).
7. according to the hypodermis inner sensor device of the controlled implant angle described in claim 3 or 4 or 5 or 6, it is characterized in that: also include sensor unit (9), described sensor unit (9) includes the sensor installation seat (901) staying skin outer portion for fixing implantable sensor, it is plugged in described sensor installation seat (901) and described implantable sensor can be implanted half pin (902) that the internal subpackage of skin wrap and and described half pin (902) connects and described half pin (902) can be driven after the implanted skin of described implantable sensor under external force from described sensor installation seat (901) to the separation block (903) of extraction outside skin.
The hypodermis inner sensor device controlling implant angle the most according to claim 7, it is characterised in that: described half pin (902) includes the half straight tube (90201) with needle point and the bending tube (90202) connected with described half straight tube (90201)；Described separation block (903) is provided with the straight trough (90301) coordinated with described half straight tube (201) and the bending groove (90302) coordinated with described bending tube (90202).
The hypodermis inner sensor device controlling implant angle the most according to claim 8, it is characterized in that: described sensor installation seat (901) includes being provided with upper pedestal (90102) and the lower base (90103) of contact installing hole (90101), described upper pedestal (90102), lower base (90103) are respectively equipped with circular groove (90104), lower arc groove (90105), described upper circular groove (90104), lower arc groove (90105) constitute for described half pin (902) pass through hole (90106)；Described upper pedestal (90102) and/or described lower base (90103) are provided with fixes groove (90107) with the described biology sensor communicated through hole (90106).
The hypodermis inner sensor device controlling implant angle the most according to claim 9, it is characterised in that: it is provided with the locating convex block (90108) cooperated and location shrinkage pool (90109) between described upper pedestal (90102) and described lower base (90103).
The 11. hypodermis inner sensor devices controlling implant angle according to claim 7, it is characterised in that: described sensor installation seat (901) and described separation block (903) end are provided with the hole, location (90110) and locating piece (90303) making described sensor installation seat (901) and described separation block (903) carry out positioning when connecting.
The 12. hypodermis inner sensor devices controlling implant angle according to claim 7, it is characterised in that: described sensor installation seat (901) is provided with a pair bayonet socket (90111).
The 13. hypodermis inner sensor devices controlling implant angle according to claim 7, it is characterized in that: described sensor installation seat (901) upper surface is provided with the first linear guide slot (90112), described separation block (903) is provided with the second linear guide slot (90304) communicated with described first linear guide slot (90112), and described first linear guide slot (90112), the second linear guide slot (90304) are two.
14. according to the hypodermis inner sensor device of the controlled implant angle described in claim 1 or 2 or 3 or 4 or 5 or 6, it is characterized in that: also include the upper cover (6) being arranged on described fixing seat (1) and described implant block (2), wireless signal transmitter is installed on described upper cover (6), described fixing seat (1) is provided with button cell (5).
The 15. hypodermis inner sensor devices controlling implant angle according to claim 14, it is characterised in that: described upper cover (6) includes lid (601) and the L-shaped extension board (602) downwardly extended for a pair being arranged on described lid (601)；Described fixing seat (1), implant block (2) are provided with the first slot (102), the second slot (203) matched with described L-shaped extension board (602).
The 16. hypodermis inner sensor devices controlling implant angle according to claim 15, it is characterized in that: described fixing seat (1) is provided with the elastic locking plate (103) being positioned at described first slot (102) top and extending to described implant block (2) direction, gap is had between described elastic locking plate and described implant block (2) lateral surface, described elastic locking plate one end is fixed on described fixing seat (1), and the other end is free end.
17. the hypodermis inner sensor device according to the controlled implant angle described in claim 1 or 2 or 3 or 4 or 5 or 6, it is characterised in that: described fixing seat (1) and described implant block (2) lower surface are provided with for the adhesive plaster (7) fixing with skin.
nullThe 18. hypodermis inner sensor devices controlling implant angle according to claim 7，It is characterized in that: described implantable sensor (10) includes the blank electrode (1001) of sheet、The reference electrode (1002) of sheet、The working electrode (1003) of sheet and sheet to electrode (1004)，Described blank electrode (1001) includes the first flexible test section (100102) of the first electrical contact portion (100101) and elongated strip，Described reference electrode (1002) includes the second flexible test section (100202) of second circuit contact site (100201) and elongated strip，Described working electrode (1003) includes the 3rd flexible test section (100302) of tertiary circuit contact site (100301) and elongated strip，Described the 4th flexible test section (100402) that electrode (1004) is included the 4th electrical contact portion (100401) and elongated strip，Described blank electrode (1001)、Reference electrode (1002)、Working electrode (1003) and electrode (1004) is built up includes the first electrical contact portion (100101)、Second circuit contact site (100201)、Tertiary circuit contact site (100301)、The testing circuit contact site (1005) in the 4th electrical contact portion (100401) and include the first flexible test section (100102)、Second flexible test section (100202)、3rd flexible test section (100302)、4th the flexible of flexible test section (100402) implants test section (1006)；Described first electrical contact portion (100101), second circuit contact site (100201), tertiary circuit contact site (100301) and the 4th electrical contact portion (100401) are respectively provided with electric contact (1007), and after described first electrical contact portion (100101), second circuit contact site (100201), tertiary circuit contact site (100301) and the 4th electrical contact portion (100401) are built up testing circuit contact site (1005), each electric contact (1007) is exposed independent from.
The 19. hypodermis inner sensor devices controlling implant angle according to claim 18, it is characterised in that: the described flexible structural strength implanting test section (1006) reduces to the end away from described testing circuit contact site (1005) gradually from the root being connected with described testing circuit contact site (1005).
The 20. hypodermis inner sensor devices controlling implant angle according to claim 19, it is characterized in that: the described first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) become big successively away from the end of described testing circuit contact site (1005) and the distance of described testing circuit contact site (1005), and described 3rd flexibility test section (100302), the 4th flexibility test section (100402) are away from the end face flush of described testing circuit contact site (1005).
The 21. hypodermis inner sensor devices controlling implant angle according to claim 19, it is characterised in that: the described first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) and the 4th flexible test section (100402) become big successively away from the end of described testing circuit contact site (1005) and the distance of described testing circuit contact site (1005).
The 22. hypodermis inner sensor devices controlling implant angle according to claim 18, it is characterised in that: the described first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) and the 4th flexible test section (100402) width are equal；Described first electrical contact portion (100101), second circuit contact site (100201), tertiary circuit contact site (100301) and the 4th electrical contact portion (100401) width are equal.
The 23. hypodermis inner sensor devices controlling implant angle according to claim 18, it is characterised in that: the length and width ratio of the described first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) and the 4th flexible test section (100402) is more than 10.
The 24. hypodermis inner sensor devices controlling implant angle according to claim 18, it is characterised in that: the described first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) and the 4th flexible test section (100402) they are cuboid.
The 25. hypodermis inner sensor devices controlling implant angle according to claim 18, it is characterised in that: described first electrical contact portion (100101), second circuit contact site (100201), tertiary circuit contact site (100301) and the 4th electrical contact portion (100401) they are cuboid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310724053.3A CN103750819B (en) | 2013-12-25 | 2013-12-25 | The hypodermis inner sensor device of implant angle can be controlled |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310724053.3A CN103750819B (en) | 2013-12-25 | 2013-12-25 | The hypodermis inner sensor device of implant angle can be controlled |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103750819A CN103750819A (en) | 2014-04-30 |
| CN103750819B true CN103750819B (en) | 2016-08-31 |
Family
ID=50518266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310724053.3A Active CN103750819B (en) | 2013-12-25 | 2013-12-25 | The hypodermis inner sensor device of implant angle can be controlled |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103750819B (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105193421B (en) * | 2014-06-13 | 2020-05-05 | 尔湾投资控股有限公司 | Real-time dynamic glucose single soft needle sensor and special needle assisting device thereof |
| WO2018027940A1 (en) * | 2016-08-12 | 2018-02-15 | Medtrum Technologies Inc. | Transcutaneous analyte sensing system and methods of installation thereof |
| CN114732401A (en) | 2018-11-13 | 2022-07-12 | 利多(香港)有限公司 | Detection unit of implantable analyte sensor |
| CN109998560B (en) * | 2019-04-30 | 2023-12-22 | 苏州百孝医疗科技有限公司 | Separated power supply dynamic blood glucose monitoring transmitter, system and signal sampling method |
| US11399747B2 (en) | 2019-08-02 | 2022-08-02 | Bionime Corporation | Physiological signal monitoring device |
| EP4017357A4 (en) * | 2019-08-19 | 2023-04-19 | Medtrum Technologies Inc. | Sensing device |
| CN110554075B (en) * | 2019-08-22 | 2022-03-15 | 北京怡成生物电子技术股份有限公司 | Flexible electrode and preparation method thereof, enzyme sensor and preparation method thereof |
| CN113274001B (en) * | 2020-02-20 | 2023-07-25 | 上海移宇科技股份有限公司 | Mounting unit for analyte detection device and method of mounting the same |
| CN111772643B (en) * | 2020-07-22 | 2022-10-25 | 浙江凯立特医疗器械有限公司 | Automatic pasting device for production of skin fixing seat and working method |
| US20220110554A1 (en) * | 2020-10-14 | 2022-04-14 | Bionime Corporation | Insertion needle structure and inserter |
| CN112450918B (en) * | 2020-11-27 | 2022-12-06 | 浙江凯立特医疗器械有限公司 | Implanting device of implantable biosensor |
| CN113827230A (en) * | 2021-10-09 | 2021-12-24 | 浙江凯立特医疗器械有限公司 | Implantable biosensor implanter |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5527182A (en) * | 1993-12-23 | 1996-06-18 | Adt Advanced Dental Technologies, Ltd. | Implant abutment systems, devices, and techniques |
| CN2782015Y (en) * | 2004-12-08 | 2006-05-24 | 圣美迪诺医疗科技(湖州)有限公司 | Subcutaneous implantation type biosenser |
| CN101146492A (en) * | 2005-02-22 | 2008-03-19 | 桑科·蒙多尔夫 | Intergral or double-split tooth implant system |
| CN103040513A (en) * | 2011-10-14 | 2013-04-17 | 巴奥米特制造公司 | Percutaneous plug for delivering power to implantable subcutaneous electrical socket |
| CN203291388U (en) * | 2013-03-28 | 2013-11-20 | 河南理工大学 | Biological electrode fixing device |
| CN203677060U (en) * | 2013-12-25 | 2014-07-02 | 浙江凯立特医疗器械有限公司 | Sensor device capable of controlling implanting angle in subcutaneous tissue |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080242961A1 (en) * | 2004-07-13 | 2008-10-02 | Dexcom, Inc. | Transcutaneous analyte sensor |
| JP5110953B2 (en) * | 2007-05-02 | 2012-12-26 | 国立大学法人九州大学 | Implant |
| CN201624764U (en) * | 2010-01-29 | 2010-11-10 | 王卫国 | Orthopedic external fixing device |
| JP5748595B2 (en) * | 2010-08-30 | 2015-07-15 | アークレイ株式会社 | Sensor insertion / recovery device |
-
2013
- 2013-12-25 CN CN201310724053.3A patent/CN103750819B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5527182A (en) * | 1993-12-23 | 1996-06-18 | Adt Advanced Dental Technologies, Ltd. | Implant abutment systems, devices, and techniques |
| CN2782015Y (en) * | 2004-12-08 | 2006-05-24 | 圣美迪诺医疗科技(湖州)有限公司 | Subcutaneous implantation type biosenser |
| CN101146492A (en) * | 2005-02-22 | 2008-03-19 | 桑科·蒙多尔夫 | Intergral or double-split tooth implant system |
| CN103040513A (en) * | 2011-10-14 | 2013-04-17 | 巴奥米特制造公司 | Percutaneous plug for delivering power to implantable subcutaneous electrical socket |
| CN203291388U (en) * | 2013-03-28 | 2013-11-20 | 河南理工大学 | Biological electrode fixing device |
| CN203677060U (en) * | 2013-12-25 | 2014-07-02 | 浙江凯立特医疗器械有限公司 | Sensor device capable of controlling implanting angle in subcutaneous tissue |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103750819A (en) | 2014-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103750819B (en) | The hypodermis inner sensor device of implant angle can be controlled | |
| US20220117523A1 (en) | Method and Apparatus for Detecting False Hypoglycemic Conditions | |
| EP1148808B1 (en) | Holter-type monitor system comprising an analyte sensor | |
| US20110028803A1 (en) | Method and device for non-invasive determination of the concentration of a substance in a body fluid | |
| US4834101A (en) | Catheter-type electrochemical sensors | |
| ES2776474T3 (en) | Continuous analyte measurement system | |
| US20230029902A1 (en) | Integrated closed-loop artificial pancreas and data obtaining method for program module thereof | |
| WO2006062668A3 (en) | Catheter-free implantable needle biosensor | |
| US9314631B2 (en) | Tongue sensors for monitoring multiple physiological parameters and tongue stimulation | |
| WO2018201931A1 (en) | Analyte monitoring and automatic medication delivery system | |
| JP2005520648A (en) | Subcutaneous insertion device insertion without trauma | |
| CN206424078U (en) | Biological sensor electrode elastic force type implanted device | |
| TW202000135A (en) | Flexible ultra low profile transcutaneous continuous monitoring sensor | |
| AU2019414451A1 (en) | Analyte sensor break-in mitigation | |
| CN203677060U (en) | Sensor device capable of controlling implanting angle in subcutaneous tissue | |
| TWI730503B (en) | Physiological and biochemical monitoring device | |
| JP4381705B2 (en) | Transcutaneous analyte extraction system and analysis system, and transcutaneous analyte extraction method and analysis method | |
| EP1552782A1 (en) | Analyte extracting device, kit and method, and blood sugar measuring device and method | |
| CN114432536A (en) | Integrated device and method for dynamic blood glucose monitoring and insulin injection fusion | |
| CN214259317U (en) | Novel implantable biosensor | |
| CN208921649U (en) | A kind of analyte monitoring system | |
| CN108982604A (en) | The portable monitoring system of analyte in a kind of dynamic METHOD FOR CONTINUOUS DETERMINATION body fluid | |
| CN204542143U (en) | Miniature dynamic glucometer probe | |
| CN216257096U (en) | Adjustable emitter device | |
| CN211460231U (en) | Single-electrode implanted blood glucose sensor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |