CN203677060U - Sensor device capable of controlling implanting angle in subcutaneous tissue - Google Patents
Sensor device capable of controlling implanting angle in subcutaneous tissue Download PDFInfo
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- CN203677060U CN203677060U CN201320861625.8U CN201320861625U CN203677060U CN 203677060 U CN203677060 U CN 203677060U CN 201320861625 U CN201320861625 U CN 201320861625U CN 203677060 U CN203677060 U CN 203677060U
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Abstract
The utility model discloses a sensor device capable of controlling the implanting angle in subcutaneous tissue. The sensor device comprises a fixed seat and an implanting seat; a hard needle tube through hole is formed in the implanting seat rotationally connected with the fixed seat. The sensor device has the advantages that after an implanting biosensor is enabled to be conveniently implanted in the subcutaneous tissue, and the implanting angle of the biosensor in the subcutaneous tissue is adjusted as required, so that the effective length of the implanting biosensor in the subcutaneous tissue is relatively long, and measured numerical value precision is relatively high, and the measured numerical value is nearer to the actual numerical value.
Description
Technical field
This utility model relates to technical field of medical instruments, relates in particular a kind of subcutaneous tissue inner sensor device of the implant angle controlled of using in the time that implantating biological sensors is implanted in skin fast.
Background technology
The diagnosis and treatment of numerous disease need to obtain continuous physiological parameter, such as body temperature, heart rate, blood pressure, blood oxygen, blood glucose etc.In these parameters, some parameter can directly be used physical methods, such as temperature, heart rate in-vitro measurements at any time; But some parameter but cannot obtain from in-vitro measurements, be exactly an example of giving prominence to such as diabetics needs Monitoring Blood Glucose, must just can obtain from measuring blood or tissue fluid; The method of measuring tissue fluid is continuous monitoring means available in reality; its advantage is needn't take a blood sample continuously or by sensor implantable intravascular; the apparatus carrying as daily patient; do not introduce and infect or the excessive risk such as lose blood; can effectively provide again essential data, so become the important directions of clinical monitoring development.Taking blood sugar test as example, along with significantly increasing of onset diabetes rate in recent years in the world, blood sugar monitoring has been more and more requisite clinical means, mainly tip blood glucose (finger tip blood) single measurement for the product of patient's self detecting blood sugar at present, but to the type ii diabetes patient of type i diabetes or use insulin treatment, individual other single measurement does not often reach the requirement of controlling blood glucose.Need a method that continuous blood sugar monitoring can be provided, make patient know at any time own blood glucose condition, take measures in time, can control most effectively the state of an illness, prevent complication, obtain higher quality of life.
Can be used at present clinical blood glucose and monitor continuously product, the technical microsensor (Medtronic, Sheng Meidinuo, Abbott Laboratories, DexCom) that only has subcutaneous tissue to be implanted into of checking to a certain extent that obtains, these products will lean on peripheral blood between patient oneself collection, measuring blood concentration value is calibrated sensor, does not all reach the degree of independent calibration and reliable Quality Control.The congenital defect of this mode refers to that it is not just reliable reference method that blood is surveyed blood glucose itself, and deviation range is larger, is can only be for patient provides one with reference to scope, instead of has the exact value of quality assurance by clinical regulation.Technology still can not provide effective tissue fluid to survey the method for blood glucose at present, therefore with referring to that it is a transient mode of having no idea that blood blood glucose meter measurement result is carried out calibrating tissue liquid sensor, therefore the further promotion and application of subcutaneous dynamic monitoring product have also been limited, in addition, known subcutaneous sensor technology is all to implant with fixed angle transdermal, hard sensor or with 90 degree right angles perpendicular to skin, or tilt and skin with a certain oblique angle, all to contact with organized layer in the mode through hypodermis layer, its intrinsic drawback is to only have finite length or area contact hypodermis layer, being unfavorable for obtaining high s/n ratio and background eliminates.
Utility model content
The purpose of this utility model is to provide for the deficiencies in the prior art part, a kind of subcutaneous tissue inner sensor device of controlling implant angle is provided, can overcome the deficiencies in the prior art part, it can make implantating biological sensors implant easily in subcutaneous tissue, can adjust as required implantating biological sensors and implant the angle in skin histology, make the effective length of implantating biological sensors in subcutaneous tissue longer simultaneously; The numerical value degree of accuracy measuring is higher, and actual numerical value is more approaching, has improved the efficiency that sensor is implanted.
In order to solve the problems of the technologies described above, the technical solution of the utility model is as follows: the subcutaneous tissue inner sensor device that can control implant angle, comprise for fixing holder and the implant block of skin, described implant block be provided with hard needle tubing by mouth and and described holder be rotatably connected.
The applicant is that test is found afterwards through research repeatedly, why present implantating biological sensors certainty of measurement and actual value has gap, can not meet the demands completely, because the effective length of implantating biological sensors in subcutaneous tissue is shorter, effectively the live part of contact tissue liquid is the 3-5mm degree of depth below after entering skin corium, again due to different people colony or health different parts or fat deposit varied in thickness very large, fashionable at health diverse location perpendicular insertion, the degree of depth is greater than 6mm and just often runs into the situation of thrusting muscle and produce pain.So in fact a vertical hard sensor length of implanting can not be greater than 6mm, otherwise will produce pain in the abundant position of muscle.
Existing implantating biological sensors is in implanting skin, generally with 90 °, the angle of 45 ° is implanted, this effective length that just makes to implant the implantating biological sensors in subcutaneous tissue is shorter, under complicated body fluid environment, the numerical value of measuring and actual value difference are larger, for this reason, applicant develops the subcutaneous tissue inner sensor device of the application's that knows clearly the implant angle controlled, this pedestal is divided into the holder and the implant block that are hinged, when in use, first holder is fixed on skin, then rotate implant block, make its extruding skin, with holder shape in an angle, this angle is according to the position of implanting skin, the situations such as angle are determined, then by hard needle tubing parcel for implantating biological sensors, be implanted in subcutaneous tissue, in implanting, hard needle tubing roughly becomes 180 ° of angles with holder, make implantating biological sensors with parallel with skin surface or connect subparallel mode and implant, such mode can make the length in implantating biological sensors implantation subcutaneous tissue not be subject to the restriction of skin thickness, its effective length is longer, make the result of detection more accurate.
As preferably, described implant block and described holder are provided with the peristome and the protuberance that cooperatively interact described holder and described implant block are rotatably connected.
As preferably, on described implant block, be hinged with guide holder, the hard needle tubing outlet that described guide holder is provided with guide chute and communicates with described guide chute.
As preferably, also comprise for described guide holder is fixed on to the locking and fixing device on described implant block, described locking and fixing device comprises and is arranged on described guide holder and described implant block, cooperatively interact latch segment and locking teeth.
As preferably, described latch segment is arranged on described guide holder two relative side, and described locking teeth is located on described implant block, and described locking teeth comprises support plate and is fixed on the pawl on described support plate top.
As preferably, described implant block is provided with the mouth that holds for placing described guide holder, and described guide chute bottom is provided with inclination elastic plate.
As preferably, mounting groove is established in described guide chute bottom, and described inclination elastic plate one end is fixed in described mounting groove, and the other end is free end and stretches out described mounting groove and enter in described guide chute.
As preferably, also comprise sensor unit, described sensor unit comprises for fixing implantable sensor stays the sensor installation seat of the outer part of skin, the separation block that is plugged on described sensor installation seat and described implantation device sensor can be implanted to inner point of half pin wrapping up of skin and be connected with described half pin and can drive under external force described half pin to extract out outside skin from described sensor installation seat after the implanted skin of described implantable sensor.
Installation of sensors assembly, when in use, biosensor with stratiform, implanting device and the subcutaneous tissue inner sensor device that can control implant angle are used in conjunction with, biosensor comprises flexible test section and the testing circuit contact site implanted, wherein, the flexible test section of implanting is implanted in skin, testing circuit contact site is stayed skin outside, when in use, sensor unit is arranged on implanting device, then utilize the spring force of Compress Spring in implanting device, drive sensor unit of the present utility model to advance, reach behind precalculated position, installation of sensors assembly and implanting device are separated, half pin is implanted test section with flexibility and is implanted in skin, simultaneously, under the effect of extension spring, separation block is return fast with half pin, whole process is very rapid, realize the exiting fast of quick implantation, half pin of biosensor, in implantation process, patient does not keenly feel, implantation speed is fast, efficiency is high, effective, simultaneously, what stay stays in guide holder with the fixing sensor installation seat of biosensor and is fixed in the subcutaneous tissue inner sensor device that can control implant angle, until detected.
As preferably, described implant block and described holder are provided with the peristome and the protuberance that cooperatively interact described holder and described implant block are rotatably connected.Being rotatably connected, can be the modes such as hinged, pivot joint.
As preferably, described half pin comprises the bending tube that has the half straight tube of needle point and be connected with described half straight tube; Described separation block is provided with the straight trough coordinating with described half straight tube and the bending groove coordinating with described bending tube.
Half pin is along axially offering elongated slot opening, with wrapping biological sensor, especially the flexibility of biosensor is implanted test section, and be connected with sub-material seat for the ease of half pin, be just provided with the structure of bending tube and bending groove, by the bending of half needle end part, put into bending groove, both convenient, be convenient to again processing, also realized the object connecting simultaneously.
As preferably, described sensor installation seat comprises the upper pedestal and the lower base that are provided with contact installing hole, described upper pedestal, lower base are respectively equipped with circular groove, lower arc groove, described upper circular groove, lower arc groove be configured for that described half pin passes through hole; Described upper pedestal and/or described lower base are provided with and the described biosensor holddown groove communicating through hole.
Sensor installation seat is divided into two parts, is convenient to the grafting of the fixing and half pin to biosensor, between two parts, can bond by glue, also can be spirally connected or engage, the setting of biosensor holddown groove, makes the fixing more firm of biosensor, and position is more accurate.
As preferably, between described upper pedestal and described lower base, be provided with the locating convex block and the location shrinkage pool that cooperatively interact.
Locating convex block and location shrinkage pool can make upper pedestal and lower base accurate positioning, are convenient to install fixing.
As preferably, described sensor installation seat is provided with described separation block end the locating hole and the locating piece that in the time being connected, make described sensor installation seat and described separation block position.
In actual use, for reducing volume, separation block and sensor installation seat fit together, and are installed in implanting device for the ease of whole sensor unit, the locating hole that is just provided with locating piece and coordinates with it.
As preferably, described sensor installation seat is provided with a pair of bayonet socket.
The existence of bayonet socket, sensor installation seat can be connected with implanting device, ensure the fastness accurately and after installing of its position, can in not working, not depart from, meanwhile, bayonet socket is arranged on side, again can be in needs, hightail with implanting device timely, ensure the smooth of the whole implantation process of biosensor.
As preferably, described sensor installation seat upper surface is provided with the first linear guide groove, and described separation block is provided with the second linear guide groove communicating with described the first linear guide groove, and described the first linear guide groove, the second linear guide groove are two.
The existence of first, second linear guide groove, coordinate with linear guides, make sensor installation seat in carrying out biosensor implantation, can take the air line, not occurrence positions skew, ensures the accurate of biosensor implantation position, simultaneously, ensure separation block accurately, return timely, half pin is extracted.
As preferably, on described holder, button cell is installed.
As preferably, also comprise the upper cover being arranged on described holder and described implant block, cover on described wireless signal transmitter is installed.
Upper cover couples together by holder and implant block, both protection can be got up again, electric elements etc. can also be set, and implantating biological sensors matches therein.The data that wireless signal transmitter detects implantating biological sensors spread out of wirelessly, are received by receptor, adopt wireless mode, do not need electric wire to connect.
As preferably, described upper cover comprises lid and is arranged on a pair of L shaped extension board to downward-extension on described lid; Described holder, implant block are provided with and described L shaped extension board matches the first slot, the second slot.
As preferably, described holder is provided with the elastic locking plate that is positioned at described the first slot top and extends to described implant block direction, gapped between described elastic locking plate and described implant block lateral surface, its one end is fixed on described holder, and the other end is free end.
The existence of elastic locking plate, makes in the engaging of upper cover and holder, its can be inwardly described in, be convenient to engaging, after contraction, outwards open, make the connection after engaging more firm.
As preferably, described holder and described implant block lower surface be provided with for the fixing adhesive plaster of skin.
Adhesive plaster adopts conventional medical proof fabric, holder and implant block can be bonded and fixed on skin.
As preferably, described adhesive plaster is at described holder and described implant block intersection is provided with the entirety of interrupted opening or for being separately positioned on two on described holder and described implant block.
As preferably, described implantating biological sensors comprises the blank electrode of lamellar, the reference electrode of lamellar, the working electrode of lamellar and lamellar to electrode, described blank electrode comprises the first flexible test section of the first circuit contact site and elongated strip, described reference electrode comprises the second flexible test section of second circuit contact site and elongated strip, described working electrode comprises the 3rd flexible test section of tertiary circuit contact site and elongated strip, described the 4th flexible test section that electrode is comprised to the 4th circuit contact site and elongated strip, described blank electrode, reference electrode, working electrode and superimposed rear formation comprises the first circuit contact site to electrode, second circuit contact site, tertiary circuit contact site, the testing circuit contact site of the 4th circuit contact site and comprise the first flexible test section, the second flexible test section, the 3rd flexible test section, the flexibility of the 4th flexible test section is implanted test section, described the first circuit contact site, second circuit contact site, tertiary circuit contact site and the 4th circuit contact site are equipped with electric contact, and when described the first circuit contact site, second circuit contact site, tertiary circuit contact site and the stack of the 4th circuit contact site form after testing circuit contact site, each electric contact all exposes.
The applicant finds after research repeatedly and experiment, the environment that subcutaneous sensor is worked in subcutaneous tissue, under being, be discrepant with ideal conditions, what under ideal conditions, detect is all pure solution, without any interference, and in actual detection, in hypodermic tissue fluid, have that adipose cell etc. is multiple to be existed without related substance, there is the detection of meeting disturb sensor in these, for this reason, the special disposal background drift of implantable sensor of the present utility model and the rectification electrode of chemical interference, namely blank electrode, utilize the time dependent background of blank electrode pair and random disturbances immediately to correct, for signal processing provides the variable of eliminating background and interference, thereby make the specificity of sensor signal and accuracy more secure, being conducive to obtain high s/n ratio and background eliminates, and the function of reference electrode is to provide reference voltage current potential as working electrode and blank electrode, make working electrode voltage remain on effective oxidation reduction electro-dynamic potential, working electrode is bio-sensing electrode, on electrode surface, has bio-sensing layer, can detect analyzed molecule, and on electrode, form signal code, provide closed loop current to electrode for whole circuit, form current loop.
In addition, applicant further finds, it is based on hard material or hard substrate that existing biosensor has some, the existence of hard material or hard substrate, make in the time that implantation is hypodermic, it produces larger stimulation to subcutaneous tissue, first this can produce a sense of discomfort, make people have the existence of foreign body sensation, be unfavorable for the long storage time of biosensor, secondly, hard material or hard substrate are in use, can continue to stimulate subcutaneous tissue surrounding, subcutaneous tissue is changed, depart from normal condition, make to detect the numerical value and the actual difference that obtain larger, and be also a disadvantageous factor to sensor biocompatibility.Therefore, laminated structure made by biosensor by applicant, after being made to lamellar, each electrode is overlapped into one, described here is superimposed, refer to the blank electrode of lamellar, the reference electrode of lamellar, the working electrode of lamellar and lamellar to after electrode stack, secure bond is integral, can adopt glue bonding, also can adopt the mode of binding, or the mode of bookbinding, or the various ways such as mutual engaging, four electrodes of laminated structure are superimposed, can reduce sensor bulk as far as possible, in addition, whole biosensor or to enter the part detecting in subcutaneous tissue be flexible, both combine and make whole biosensor in tissue, produce less lasting stimulation, greatly increase the degree of the true physiological environment of sensor senses and state, improve accuracy of detection, make its measured value and actual value more approaching.
As preferably, described blank electrode, reference electrode, working electrode and to electrode stack successively from top to bottom.
Adopt combination order above to superpose, the numerical value and the actual value that detect are more approaching.
As preferably, the described flexible structural strength of implanting test section is from the root being connected with described testing circuit contact site to gradually reducing away from the end of described testing circuit contact site.。
Gradually reducing of structural strength, can be linear, can be also stair-stepping, such frame mode, make the flexible test section of implanting away from root process, thickness changes, and becomes thinner, further reduces the stimulation to tissue, same, in the process of its thickness near root, pliability strengthens, and can prevent fracture, because along with gradually near root, it is stressed also increasing, if sensor thickness is made unanimously, thinner for fear of what stimulate subcutaneous tissue to do, just easily rupture or occur crack, the place of especially close root, it is stressed larger, stress is more concentrated, also just more easily fracture, more easily there is crack, and these all can affect the certainty of measurement of sensor, if and select thicker thickness, very large to hypodermic stimulation, also can affect accuracy of detection, and the mode of employing the technical program, reduced hypodermic stimulation, ensure again structural strength, and then improve accuracy of detection.
As preferably, described the first flexible test section, the second flexible test section, the 3rd flexible test section become greatly successively away from the end of described testing circuit contact site and the distance of described testing circuit contact site, and described the 3rd flexible test section, the 4th flexible test section are mutually concordant away from the end face of described testing circuit contact site.
As preferably, described the first flexible test section, the second flexible test section, the 3rd flexible test section and the 4th flexible test section become large successively away from the end of described testing circuit contact site and the distance of described testing circuit contact site.
As preferably, described the first flexible test section, the second flexible test section, the 3rd flexible test section and the 4th flexible test section width equate; Described the first circuit contact site, second circuit contact site, tertiary circuit contact site and the 4th circuit contact site width equate.
Above-mentioned setting, is convenient to make and install, and makes the volume of whole biosensor as much as possible little, especially most probably little of the volume of four flexible test sections simultaneously.
As preferably, length and the width ratio of described the first flexible test section, the second flexible test section, the 3rd flexible test section and the 4th flexible test section are greater than 10.
As preferably, described the first flexible test section, the second flexible test section, the 3rd flexible test section and the 4th flexible test section are cuboid.
As preferably, described the first circuit contact site, second circuit contact site, tertiary circuit contact site and the 4th circuit contact site are cuboid.
A kind of method of manufacturing implantating biological sensors; 1. make lamellar and there is the blank electrode base board, reference electrode substrate, working electrode substrate of electric contact and to electrode base board; 2. by the blank electrode base board making, reference electrode substrate, working electrode substrate and superimposed according to predefined procedure to electrode base board after cut, form testing circuit contact site and the flexible test section of implanting.
This manufacture method, to the manufacture of each electrode, adopts integral planar technique, after producing four electrodes of lamellar, then bonding is fixing, then cutting, its whole industrial process, technical maturity is high, is applicable to batch production, simple and reliable, produced biosensor, the more forward end of pliability is better, and good biocompatibility is light to tissue stimulation.
This utility model beneficial effect is:
1) can make implantating biological sensors implant in subcutaneous tissue easily, and adjust as required implantating biological sensors and implant the angle in skin histology, make the effective length of implantating biological sensors in subcutaneous tissue longer; The numerical value degree of accuracy measuring is higher, and actual numerical value is more approaching, has improved the efficiency that biosensor is implanted;
2) by biosensor assembly, can make implantable sensor implant in subcutaneous tissue fast, and half pin is exited fast, whole process is very rapid, and in implantation process, patient does not keenly feel, and it is high that biosensor is implanted efficiency, implants effective.
3) after implantable sensor is implanted in subcutaneous tissue, the stimulation of generation is smaller, and foreign body sensation is little, and the data value and the actual value that detect are more approaching.
Brief description of the drawings
Below in conjunction with accompanying drawing, this utility model is described further:
Fig. 1 is the structural representation of an embodiment of the present utility model;
Fig. 2 is the three-dimensional exploded view of Fig. 1;
Fig. 3 is holder and implant block connection diagram;
Fig. 4 is schematic diagram after holder and implant block, mount pad and the subcutaneous tissue inner sensor device that can control implant angle are installed;
Fig. 5 is the application schematic diagram of this utility model one embodiment;
Fig. 6 is the structural representation after sensor installation seat, half pin and separation block connect;
Fig. 7 is the exploded view of Fig. 6;
Fig. 8 sensor installation seat and guide holder connection diagram;
Fig. 9 is that Fig. 8 decomposes the schematic diagram coming;
Figure 10 is sensor installation seat exploded view;
Figure 11 is the structure chart of implantable sensor;
Figure 12 is the three-dimensional exploded view of Figure 11;
Figure 13 is the axonometric chart of Figure 11.
In figure:
1, holder, 101, protuberance, 102, the first slot, 103, elastic locking plate, 2, implant block, 201, peristome, 202, hold mouth, 203, the second slot, 204-hard needle tubing by mouthful, 205-protruding plate, 3, guide holder, 301, guide chute, 302, the outlet of hard needle tubing, 303, inclination elastic plate, 304, mounting groove; 4, locking and fixing device, 401, latch segment, 402, locking teeth, 5, button cell, 6, upper cover, 601, lid, 602, L shaped extension board, 7, adhesive plaster, 8, implanting device; 9, sensor unit, 901, sensor installation seat, 90101, contact installing hole, 90102, upper pedestal, 90103, lower base, 90104, upper circular groove, 90105, lower circular groove, 90106, through hole, 90107, sensor holddown groove, 90108, locating convex block, 90109, location shrinkage pool, 90110, locating hole, 90111, bayonet socket, 90112, the first linear guide groove, 90113, inclination draw-in groove; 902, half pin, 90201, half straight tube, 90202, bending tube, 903, separation block, 90301, straight trough, 90302, bending groove, 90303, locating piece, 90304, the second linear guide groove; 1001, blank electrode, 100101, the first circuit contact site, 100102, the first circuit contact site, 1002, reference electrode, 100201, second circuit contact site, 100202, second circuit contact site, 100 3, working electrode, 100301, tertiary circuit contact site, 100302, the 3rd flexible test section, 1004, to electrode, 100401, the 4th circuit contact site, 100402, the 4th flexible test section, 1005, testing circuit contact site, 1006, the flexible test section of implanting, 1007, electric contact.
Detailed description of the invention
The following stated is only preferred embodiment of the present utility model, not scope of the present utility model is limited.
Embodiment, see accompanying drawing 1,2,3,4,5,6,7,8,9,10,11,12,13, can control the subcutaneous tissue inner sensor device of implant angle, comprise can be fixing with skin holder 1 and implant block 2 that can be fixing with skin, on implant block 2, offer hard needle tubing by mouth 204, be convenient to hard needle tubing and implantating biological sensors and pass through, implant block and holder are made up of the plastics of lamellar, are transparence, end fillet processing, described implant block 2 and described holder 1 are rotatably connected, can be hinged, pivot joint etc., also can adopt gemel connection, or adopt the material of easy bending to connect, such as rubber sheet, sheet of polyurethane etc., implant block 2 can be rotated around holder 1, for this reason, described implant block 2 and described holder 1 are provided with the peristome 201 and the protuberance 101 that cooperatively interact described holder 2 and described implant block 1 are rotatably connected, in the present embodiment, described implant block 2 is provided with peristome 201, peristome is arranged on the end of implant block, it caves inward, form peristome 201, described holder 1 is provided with the protuberance 101 that stretches into described peristome 201, described protuberance 101 is hinged by rotating shaft and described peristome 201, rotating shaft is arranged on protuberance 101 two ends, insert in the side of peristome 201, realization is articulated and connected, certainly, also can be conversely, on implant block 2, protrude a part, a holder depression part, realization is articulated and connected, or carry out hinged with other known articulated manner, be not described in detail in this, implant block 2 and holder 1 are hinged, make in carrying out implantating biological sensors implantation, can carry out angular adjustment, make implantating biological sensors to become 180 ° or approximately parallel mode to implant with the skin under holder, concrete angle is determined according to practical situation, be generally 170-180 °.
Upper cover 6 on described holder 1 and described implant block 2, the interior installation wireless signal transmitter of upper cover 6, upper cover 6 adopts hard material to make, on described holder 1, button cell 5 is installed, be used to provide power supply, described upper cover 6 comprises lid 601 and is arranged on a pair of L shaped extension board 602 to downward-extension on described lid 601, described holder 1, implant block 2 is provided with the first slot 102 matching with described L shaped extension board 602, the second slot 203, in the time that upper cover covers on implant block and holder, L shaped extension board 602 snaps in the first slot 102, in the second slot 203, described holder 1 is provided with the elastic locking plate 103 that is positioned at described the first slot 102 tops and extends to described implant block 2 directions, elastic locking plate 103 is a pair of, be arranged on 2 two sides of implant block, one end is fixed on implant block 2, the other end is free end, gapped between described elastic locking plate 103 and described implant block 2 lateral surface, be fixed on skin for the ease of holder 1 and implant block 2, described holder 1 and described implant block 2 lower surfaces be provided with for the fixing adhesive plaster 7 of skin, described adhesive plaster 7 can be as a whole, also can be divided into two, as a whole time, be provided with interrupted opening at described holder 1 and described implant block 2 intersections, be convenient to implant block 2 and holder 1 rotates.
In order to raise the efficiency, we are provided with sensor unit, comprise sensor installation seat 901, half pin 902 and separation block 903, sensor installation seat 901 is fixed for the end of implantable sensor being stayed to skin, implantating biological sensors is divided into two parts, one is to implant the part detecting in skin, we are referred to as the flexible test section of implanting, one is the part of staying skin outside, be connected with other electric elements, the data of detection are sent, we are called testing circuit contact site, sensor installation seat is fixed testing circuit contact site, simultaneously, half pin 902 is plugged in sensor installation seat 901, and it can wrap up namely flexibility implantation of implantation device sensor implantation parts of skin test section, in actual work, first implantating biological sensors is arranged on sensor installation seat because be all, make again half pin 902 wrap up implantating biological sensors, therefore, half pin is actually the whole flexible test section of implanting is wrapped up, simultaneously, the part of testing circuit contact site is wrapped up, separation block 903 is connected with half pin 902, because half pin 902 is plugged in sensor installation seat, biosensor is implanted after skin completing, it can not be stayed in skin, fall back on outside, therefore, just be provided with the separation block 903 being connected with half pin 902 ends, it can drive half pin 902 to extract out fast from sensor installation seat 901 and in skin under external force.
Sensor installation seat 901 comprises upper pedestal 90102 and lower base 90103, upper pedestal 90102, upper pedestal 90102 and lower base 90103 can be spirally connected fixing or bonding is fixing, on upper pedestal 90102, be provided with contact installing hole 90101, it is used for that electric contact is installed and biosensor contacts, and detection data are sent with electrical signal form, in present embodiment, contact installing hole 90101 is four, and guide holder is provided with open ports, contacts so that four contact installing holes expose with upper cover; On upper pedestal 90102, lower base 90103, be provided with circular groove 90104, lower arc groove 90105, upper circular groove 90104, lower arc groove 90105 are symmetrical arranged, upper circular groove 90104, lower arc groove 90105 be configured for that half pin 902 passes through hole 90106, gapped through hole 90106 and half pin; Upper pedestal 90102 and/or lower base 90103 are provided with and pass the biosensor holddown groove 90107 that hole 90106 communicates, biosensor holddown groove 90107 can arrange on lower base 90103, for rectangular channel, in present embodiment, to be divided into two parts, divide and be located on upper and lower pedestal, can certainly be arranged on separately on upper pedestal; For the ease of the installation of upper pedestal 90102 and lower base 90103, between is provided with the locating convex block 90108 and the location shrinkage pool 90109 that cooperatively interact, locating convex block 90108 is cuboid, be arranged on upper pedestal lower surface, location shrinkage pool 90109 is also rectangle, and the upper surface of lower base 90103 is set; Both cooperatively interact, the location of lower base in realization, simultaneously, for the ease of being installed in implanting device, and can in needs, separate with implanting device 8 fast, sensor installation seat 901 is provided with a pair of bayonet socket 90111 near the end sides of separation block 903, and bayonet socket 90111 is circular arc, is arranged on two opposite flanks of separation block 903 ends; Coordinate with the claw of implanting device, in addition, the position of a pair of bayonet socket can be determined according to the actual requirements, for example, be arranged on centre position.
Between sensor installation seat 901 and separation block 903, be not fixedly connected with, can there is no annexation yet, but for ensure both positions accurately and biosensor implantation process smoothly, we are provided with locating hole 90110 in the end of sensor installation seat 901, separation block 903 be provided with locating hole 90110 that coordinate with locating piece 90303.Simultaneously, sensor installation seat 901 upper surfaces are provided with the first linear guide groove 90112, separation block 903 is provided with the second linear guide groove 90304 communicating with the first linear guide groove 90112, the linear guides of the first linear guide groove 90112, the second linear guide groove 90112 of linear guide groove 90,304 first and implanting device coordinates, what guarantee sensor installation seat and separation block carried out in moving forward and backward is rectilinear movement, the first linear guide groove 90112, the second linear guide groove 90304 are two, symmetrical setting.
For the ease of the implantation of sensor, also make sensor easier to implant in skin with the parallel mode of skin under holder, on described implant block 2, be hinged with guide holder 3, the hard needle tubing outlet 302 that described guide holder 3 is provided with guide chute 301 and communicates with described guide chute 301, the outlet 302 of hard needle tubing and hard needle tubing communicate by mouth 204, when use, guide chute and sensor installation seat 901 match, sensor installation seat 901 can be slided in guide chute, ensure that position is accurate, be conducive to again implant fast, simultaneously, because guide holder is hinged on implant block, can adjust according to practical situation the angle of guide holder and implant block, this setting and implant block and holder are hinged to be used in combination, implantating biological sensors is carried out to the adjusting of implant angle, so, said structure can either ensure the accurate of implantating biological sensors implantation position and improve the efficiency of implanting, make the implantating biological sensors can be convenient, be easy to implant in subcutaneous tissue, make implantating biological sensors be positioned at the effective length of subcutaneous tissue enough.
After sensor has been implanted, sensor installation seat 901 and guide holder all can be stayed on pedestal, this time, both need to be fixed, prevent its loosening variation that causes implantating biological sensors position, first need guide holder to fix, for this reason, we are provided with for described guide holder 3 is fixed on to the locking and fixing device 4 on described implant block 2, locking and fixing device 4 is to be fixed on guide holder on implant block 2 as object, a kind of structure of locking and fixing device 4 is provided now, described locking and fixing device 4 comprises and is arranged on described guide holder 3 and described implant block 2, cooperatively interact latch segment 401 and locking teeth 402, described latch segment 401 is arranged on described guide holder 3 two relative sides, described locking teeth 402 is located on described implant block 2, described locking teeth 402 comprises support plate and is fixed on the pawl on described support plate top, in locking, the masterpiece of latch segment is used on pawl side, the support plate of pawl below slopes inwardly, and then outwards open, realize the locking to latch segment, certainly, described locking and fixing device 4 also can adopt fairly simple structure, is arranged on described guide holder 3 and described implant block 2, cooperatively interact latch segment 401 and locking slot.
In addition, in order to ensure to detect effect, be provided with and hold mouthfuls 202 for what place described guide holder 3 at described implant block 2, described guide chute 301 bottoms are provided with inclination elastic plate 303, mounting groove 304 is established in described guide chute 301 bottoms, described inclination elastic plate 303 one end are fixed in described mounting groove 304, the other end is free end and stretches out described mounting groove 304 and enter in described guide chute 301, realize the elastic clamping to sensor installation seat 901 by inclination elastic plate 303, the inclination draw-in groove 90113 that sensor installation seat 1 bottom surface is provided with and the elastic plate 303 that tilts matches.And in the time adopting latch segment to lock groove as locking and fixing device 4, locking slot is arranged on and holds mouthful 202 sides, be used for engaging the latch segment 401 that is arranged on guide holder 3 sides, in the time adopting locking teeth to lock piece, hold and mouthful be provided with side and be provided with opening, locking teeth is arranged in the opening of side, holds mouthful 202 bottom surfaces and is being provided with protruding plate 205 away from the end of hard needle tubing outlet 302, be used for sensor installation seat 901 carry out spacing and clamp, prevent that it is loosening.
Implantating biological sensors 10, biosensor is layer structure, comprise the working electrode 1003 of reference electrode 1002, lamellar of blank electrode 1001, the lamellar of lamellar and lamellar to electrode 1004, four electrodes are all cuboids, integral after bonding after stack, the order of arrangement can be carried out according to the actual requirements, wherein, preferably, be followed successively by from top to bottom blank electrode 1001, reference electrode 1002, working electrode 1003 and to electrode 1004, described blank electrode 1001 comprises the first flexible test section 100102 of the first circuit contact site 100101 and elongated strip, described reference electrode 1002 comprises the second flexible test section 100202 of second circuit contact site 100201 and elongated strip, described working electrode 1003 comprises the 3rd flexible test section 100302 of tertiary circuit contact site 100301 and elongated strip, described the 4th flexible test section 100402 that electrode 1004 is comprised to the 4th circuit contact site 100401 and elongated strip, described the first flexible test section 100102, the second flexible test section 100202, why the 3rd flexible test section 100302 and the 4th flexible test section 100402 are elongated strips, in order to reduce as far as possible the stimulation to subcutaneous tissue cell, its length and width ratio are greater than 10, length-width ratio is the bigger the better, and for the ease of processing and manufacturing and obtain reasonable detection effect, described the first flexible test section 100102, the second flexible test section 100202, the 3rd flexible test section 100302 and the 4th flexible test section 100402 are cuboid, and width equates, described the first circuit contact site 100101, second circuit contact site 100201, tertiary circuit contact site 100301 and the 4th circuit contact site 100401 are cuboid, and width equates.
Blank electrode 1001, reference electrode 1002, working electrode 1003 and electrode 1004 is superposeed and is bondd after form and comprise the testing circuit contact site 1005 of the first circuit contact site 100101, second circuit contact site 100201, tertiary circuit contact site 100301, the 4th circuit contact site 100401 and comprise that the flexibility of the first flexible test section 100102, the second flexible test section 100202, the 3rd flexible test section 100302, the 4th flexible test section 100402 implants test section 1006, the flexible test section 1006 of implanting is implanted in subcutaneous tissue, detect, its directly and tissue fluid contact, testing circuit contact site 1005 is used for being connected with external circuit outside staying, and flexibility is implanted to the data that test section 1006 plant quarantine measure and send, analyze contrast, for the ease of being connected with external circuit, described the first circuit contact site 100101, second circuit contact site 100201, tertiary circuit contact site 100301 and the 4th circuit contact site 100401 are equipped with electric contact 1007, so just there are four electric contacts, and when described the first circuit contact site 100101, second circuit contact site 100201, tertiary circuit contact site 100301 and the 4th circuit contact site 100401 stacks form after testing circuit contact site 1005, each electric contact 1007 all exposes, that is to say, a part is stretched out in second circuit contact site 100201 ends that are positioned under the first circuit contact site 100101, so that electric contact is set, same, tertiary circuit contact site 100301 ends are compared second circuit contact site and are also stretched out a part, the 4th circuit contact site end is compared tertiary circuit contact site and is also stretched out a part, be used for arranging electric contact.
In order to improve the accuracy that detects numerical value, reduce foreign body sensation and reduce hypodermic stimulation, the described flexible structural strength of implanting test section 1006 is from the root being connected with described testing circuit contact site 1005 to gradually reducing away from the end of described testing circuit contact site 1005, gradually reducing can be that linearity reduces or stepped reducing, in the present embodiment, what adopt is, described the first flexible test section 100102, the second flexible test section 100202, the 3rd flexible test section 100302 becomes large successively away from the end of described testing circuit contact site 1005 and the distance of described testing circuit contact site 1005, and described the 3rd flexible test section 100302, the 4th flexible test section 100402 is mutually concordant away from the end of described testing circuit contact site 1005, between such four test sections, three ladders are just formed.
In addition, can also adopt the structure of accompanying drawing 13, described the first flexible test section 100102, the second flexible test section 100202, the 3rd flexible test section 100302 and the 4th flexible test section 100402 become greatly successively away from the end of described testing circuit contact site 1005 and the distance of described testing circuit contact site 1005, form four ladders between four test sections.
A kind of implantating biological sensors manufacture method, 1. makes lamellar and has the blank electrode base board, reference electrode substrate, working electrode substrate of electric contact 1007 and to electrode base board; Blank electrode base board, reference electrode substrate, working electrode substrate and to electrode base board now with blank electrode, reference electrode, working electrode and the difference of electrode is only to shape, remaining is all identical, 2. by the blank electrode base board making, reference electrode substrate, working electrode substrate and superimposed according to predefined procedure to electrode base board after cut, form testing circuit contact site 1005 and the flexible test section 1006 of implanting.
More than explanation is only to explanation of the present utility model, make those of ordinary skill in the art's can completely implement this programme, but be not to restriction of the present utility model, those skilled in the art are reading after this description and can make to the present embodiment the amendment that there is no creative contribution as required, and these are all not creative amendments.But as long as within the scope of claim of the present utility model, be all subject to the protection of Patent Law.
Claims (26)
1. the subcutaneous tissue inner sensor device that can control implant angle, is characterized in that: comprise holder (1) and implant block (2), described implant block (2) is provided with hard needle tubing and is rotatably connected by mouthful (204) and with described holder (2).
2. the subcutaneous tissue inner sensor device of controlling implant angle according to claim 1, is characterized in that: described implant block (2) and described holder (1) are provided with the peristome (201) and the protuberance (101) that cooperatively interact described holder (2) and described implant block (1) are rotatably connected.
3. the subcutaneous tissue inner sensor device of controlling implant angle according to claim 1, it is characterized in that: on described implant block (2), be hinged with guide holder (3), the hard needle tubing outlet (302) that described guide holder (3) is provided with guide chute (301) and communicates with described guide chute (301).
4. the subcutaneous tissue inner sensor device of controlling implant angle according to claim 3, is characterized in that: also comprise for described guide holder (3) being fixed on to the locking and fixing device (4) on described implant block (2); Described locking and fixing device (4) comprises and is arranged on described guide holder (3) and described implant block (2), cooperatively interact latch segment (401) and locking teeth (402).
5. the subcutaneous tissue inner sensor device of controlling implant angle according to claim 4, it is characterized in that: described latch segment (401) is arranged on described guide holder (3) two relative side, it is upper that described locking teeth (402) is located at described implant block (2), and described locking teeth (402) comprises support plate and is fixed on the pawl on described support plate top.
6. the subcutaneous tissue inner sensor device of controlling implant angle according to claim 3, it is characterized in that: described implant block (2) is provided with hold mouthful (202) for placing described guide holder (3), and described guide chute (301) bottom is provided with inclination elastic plate (303).
7. the subcutaneous tissue inner sensor device of controlling implant angle according to claim 6, it is characterized in that: mounting groove (304) is established in described guide chute (301) bottom, described inclination elastic plate (303) one end is fixed in described mounting groove (304), and the other end is free end and stretches out described mounting groove (304) and enter in described guide chute (301).
8. according to the subcutaneous tissue inner sensor device of the implant angle controlled described in claim 3 or 4 or 5 or 6 or 7, it is characterized in that: also comprise sensor unit (9), described sensor unit (9) comprises the sensor installation seat (901) of staying the outer part of skin for fixing implantable sensor, be plugged in described sensor installation seat (901) and the separation block (903) that described implantation device sensor can be implanted to inner point of half pin (902) wrapping up of skin and be connected with described half pin (902) and can drive under external force described half pin (902) to extract out outside skin from described sensor installation seat (901) after the implanted skin of described implantable sensor.
9. the subcutaneous tissue inner sensor device of controlling implant angle according to claim 8, is characterized in that: described half pin (902) comprises the bending tube (90202) that has the half straight tube (90201) of needle point and be connected with described half straight tube (90201); Described separation block (903) is provided with the straight trough (90301) coordinating with described half straight tube (201) and the bending groove (90302) coordinating with described bending tube (90202).
10. the subcutaneous tissue inner sensor device of controlling implant angle according to claim 9, it is characterized in that: described sensor installation seat (901) comprises the upper pedestal (90102) and the lower base (90103) that are provided with contact installing hole (90101), described upper pedestal (90102), lower base (90103) are respectively equipped with circular groove (90104), lower arc groove (90105), described upper circular groove (90104), lower arc groove (90105) be configured for that described half pin (902) passes through hole (90106); Described upper pedestal (90102) and/or described lower base (90103) are provided with the biosensor holddown groove (90107) communicating with described (90106).
The 11. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 10, is characterized in that: between described upper pedestal (90102) and described lower base (90103), be provided with the locating convex block (90108) and the location shrinkage pool (90109) that cooperatively interact.
The 12. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 8, is characterized in that: described sensor installation seat (901) is provided with described separation block (903) end the locating hole (90110) and the locating piece (90303) that in the time being connected, make described sensor installation seat (901) and described separation block (903) position.
The 13. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 8, is characterized in that: described sensor installation seat (901) is provided with a pair of bayonet socket (90111).
The 14. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 8, it is characterized in that: described sensor installation seat (901) upper surface is provided with the first linear guide groove (90112), described separation block (903) is provided with the second linear guide groove (90304) communicating with described the first linear guide groove (90112), and described the first linear guide groove (90112), the second linear guide groove (90304) are two.
15. according to the subcutaneous tissue inner sensor device of the implant angle controlled described in claim 1 or 2 or 3 or 4 or 5 or 6 or 7, it is characterized in that: also comprise the upper cover (6) being arranged on described holder (1) and described implant block (2), described upper cover is provided with wireless signal transmitter on (6), and button cell (5) is installed on described holder (1).
The 16. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 15, is characterized in that: described upper cover (6) comprises lid (601) and is arranged on a pair of L shaped extension board (602) to downward-extension on described lid (601); Described holder (1), implant block (2) are provided with the first slot (102), the second slot (203) that match with described L shaped extension board (602).
The 17. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 16, it is characterized in that: described holder (1) is provided with the elastic locking plate (103) that is positioned at described the first slot (102) top and extends to described implant block (2) direction, gapped between described elastic locking plate and described implant block (2) lateral surface, it is upper that its one end is fixed on described holder (1), and the other end is free end.
18. according to the subcutaneous tissue inner sensor device of the implant angle controlled described in claim 1 or 2 or 3 or 4 or 5 or 6 or 7, it is characterized in that: described holder (1) and described implant block (2) lower surface be provided with for the fixing adhesive plaster (7) of skin.
The 19. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 8, it is characterized in that: described implantable sensor (10) comprises the blank electrode (1001) of lamellar, the reference electrode (1002) of lamellar, the working electrode (1003) of lamellar and lamellar to electrode (1004), described blank electrode (1001) comprises the first flexible test section (100102) of the first circuit contact site (100101) and elongated strip, described reference electrode (1002) comprises the second flexible test section (100202) of second circuit contact site (100201) and elongated strip, described working electrode (1003) comprises the 3rd flexible test section (100302) of tertiary circuit contact site (100301) and elongated strip, described the 4th flexible test section (100402) that electrode (1004) is comprised to the 4th circuit contact site (100401) and elongated strip, described blank electrode (1001), reference electrode (1002), working electrode (1003) and electrode (1004) is built up and comprises the first circuit contact site (100101), second circuit contact site (100201), tertiary circuit contact site (100301), the testing circuit contact site (1005) of the 4th circuit contact site (100401) and comprise the first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302), the flexibility of the 4th flexible test section (100402) is implanted test section (1006), described the first circuit contact site (100101), second circuit contact site (100201), tertiary circuit contact site (100301) and the 4th circuit contact site (100401) all have electric contact (1007), and when described the first circuit contact site (100101), second circuit contact site (100201), tertiary circuit contact site (100301) and the 4th circuit contact site (100401) are built up after testing circuit contact site (1005), each electric contact (1007) all exposes.
The 20. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 19, is characterized in that: the described flexible structural strength of implanting test section (1006) is from the root being connected with described testing circuit contact site (1005) to gradually reducing away from the end of described testing circuit contact site (1005).
The 21. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 20, it is characterized in that: described the first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) become greatly successively away from the end of described testing circuit contact site (1005) and the distance of described testing circuit contact site (1005), and described the 3rd flexible test section (100302), the 4th flexible test section (100402) are mutually concordant away from the end face of described testing circuit contact site (1005).
The 22. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 20, is characterized in that: described the first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) and the 4th flexible test section (100402) become large successively away from the end of described testing circuit contact site (1005) and the distance of described testing circuit contact site (1005).
The 23. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 19, is characterized in that: described the first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) and the 4th flexible test section (100402) width equate; Described the first circuit contact site (100101), second circuit contact site (100201), tertiary circuit contact site (100301) and the 4th circuit contact site (100401) width equate.
The 24. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 19, is characterized in that: length and the width ratio of described the first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) and the 4th flexible test section (100402) are greater than 10.
The 25. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 19, is characterized in that: described the first flexible test section (100102), the second flexible test section (100202), the 3rd flexible test section (100302) and the 4th flexible test section (100402) are cuboid.
The 26. subcutaneous tissue inner sensor devices of controlling implant angle according to claim 19, is characterized in that: described the first circuit contact site (100101), second circuit contact site (100201), tertiary circuit contact site (100301) and the 4th circuit contact site (100401) are cuboid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320861625.8U CN203677060U (en) | 2013-12-25 | 2013-12-25 | Sensor device capable of controlling implanting angle in subcutaneous tissue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320861625.8U CN203677060U (en) | 2013-12-25 | 2013-12-25 | Sensor device capable of controlling implanting angle in subcutaneous tissue |
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| Publication Number | Publication Date |
|---|---|
| CN203677060U true CN203677060U (en) | 2014-07-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201320861625.8U Withdrawn - After Issue CN203677060U (en) | 2013-12-25 | 2013-12-25 | Sensor device capable of controlling implanting angle in subcutaneous tissue |
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| CN (1) | CN203677060U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103750819A (en) * | 2013-12-25 | 2014-04-30 | 浙江凯立特医疗器械有限公司 | Sensor device capable of controlling insertion angle in subcutaneous tissue |
| CN108903916A (en) * | 2018-07-31 | 2018-11-30 | 浙江大学 | The implant needle and method for implantation of flexible implanted biosensor and photoelectric device |
-
2013
- 2013-12-25 CN CN201320861625.8U patent/CN203677060U/en not_active Withdrawn - After Issue
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103750819A (en) * | 2013-12-25 | 2014-04-30 | 浙江凯立特医疗器械有限公司 | Sensor device capable of controlling insertion angle in subcutaneous tissue |
| CN103750819B (en) * | 2013-12-25 | 2016-08-31 | 浙江凯立特医疗器械有限公司 | The hypodermis inner sensor device of implant angle can be controlled |
| CN108903916A (en) * | 2018-07-31 | 2018-11-30 | 浙江大学 | The implant needle and method for implantation of flexible implanted biosensor and photoelectric device |
| CN108903916B (en) * | 2018-07-31 | 2024-04-02 | 浙江大学 | Implantation needle and implantation method of flexible implantation type biosensor and photoelectric device |
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