CN214259317U

CN214259317U - Novel implantable biosensor

Info

Publication number: CN214259317U
Application number: CN202022789241.2U
Authority: CN
Inventors: 杨凯洪; 费英杰
Original assignee: Zhejiang Poctech Corp
Current assignee: Zhejiang Poctech Corp
Priority date: 2020-11-27
Filing date: 2020-11-27
Publication date: 2021-09-24
Anticipated expiration: 2030-11-27

Abstract

The utility model relates to a novel implantable biosensor, for laminated structure, including blank electrode layer, working electrode layer, reference electrode layer and counter electrode layer, blank electrode layer, working electrode layer, reference electrode layer and counter electrode layer all include circuit contact site and the flexible detection portion of implanting, the transition connection part that circuit contact site and flexible between the implantation detection portion is the design of buckling, and the present case has reduced the fore-and-aft length of implantable biosensor through such design of buckling for when the sensor was implanted, need not the manual work and buckles, prolonged implantable biosensor's life.

Description

Novel implantable biosensor

Technical Field

The utility model relates to an implantation nature sensor field especially relates to a novel implantation nature biosensor.

Background

With the remarkable increase of the incidence rate of diabetes in recent years in the world, blood sugar monitoring is an increasingly indispensable clinical means, and the current products for self-testing blood sugar of patients are mainly single measurement of peripheral blood sugar (fingertip blood), but for diabetes patients or diabetes patients using insulin therapy, individual single measurement often fails to meet the requirement of blood sugar control. In recent years, a subcutaneous implantable blood glucose sensor is well-known in the field of medical diagnosis, and can monitor molecular activities, i.e., blood glucose or insulin, in living animals all year around in real time after being implanted subcutaneously.

Some existing implantable biosensors are based on hard materials or hard base materials, and the existence of the hard materials or the hard base materials can cause great stimulation to subcutaneous tissues when the implantable biosensors are implanted into the subcutaneous tissues, so that firstly discomfort can be caused, people can have foreign body sensation, and the long-time storage of the biosensors is not facilitated, secondly, the hard materials or the hard base materials can continuously stimulate the surrounding environment of the subcutaneous tissues in the using process, so that the subcutaneous tissues are changed and deviate from normal conditions, the detected numerical value and actual difference are larger, although some flexible implantable biosensors are also available in the market, for example, an implantable biosensor is disclosed in a subcutaneous tissue internal sensor device patent with the application number of CN201310724053.3 and the implantation angle can be controlled, when the implantable biosensor is implanted into an implantation seat, the implantable biosensor needs to be bent due to the overlong longitudinal length to be hidden in the implantation seat However, since the implantable biosensor is easily damaged during long-term use due to the artificial bending at the later stage, it is necessary to provide an implantable biosensor that does not require bending to solve the above problems.

The utility model has the following contents:

the utility model provides a novel implantation nature biosensor has reduced the fore-and-aft length of implantation nature biosensor for when the sensor was implanted, need not to buckle, prolonged implantation nature biosensor's life.

The utility model provides a novel implantation biosensor, is laminated structure, including blank electrode layer, working electrode layer, reference electrode layer and counter electrode layer, blank electrode layer, working electrode layer, reference electrode layer and counter electrode layer are all including circuit contact site and flexible implantation detection portion, the transition connecting portion between circuit contact site and the flexible implantation detection portion is the design of buckling.

Preferably, a bending angle B between the circuit contact part and the flexibility detection part is 120 ° to 150 °.

Preferably, the transitional connection part between the circuit contact part and the flexible detection part is in a circular arc shape;

preferably, the thickness of the blank electrode layer, the working electrode layer, the reference electrode layer 503 and the counter electrode layer 504 after lamination is 0.25 to 0.3 mm.

Preferably, the width of the flexible detection part far away from the end part of the circuit contact part is 0.07-0.14 mm.

Preferably, the structural strength of the flexible implantation detecting portion is gradually decreased from a root portion connected to the circuit contact portion 505 to an end portion distant from the circuit contact portion.

Preferably, the circuit contact portions of the blank electrode layer, the working electrode layer, the reference electrode layer and the counter electrode layer are all rectangular parallelepipeds and have the same width.

The utility model has the advantages that:

(1) the utility model discloses an implantation nature biosensor is laminated structure, including blank electrode layer, working electrode layer, reference electrode layer and counter electrode layer, blank electrode layer, working electrode layer, reference electrode layer and counter electrode layer all include circuit contact site and the flexible detection portion of implanting, the transition connection part between circuit contact site and the flexible detection portion of implanting is the design of buckling, and the present case has reduced implantation nature biosensor fore-and-aft length through such design of buckling for when the sensor was implanted, need not the manual work and buckles, prolonged implantation nature biosensor's life.

(2) The utility model discloses an angle B of buckling between circuit contact site and the flexible detection portion is 120 ~ 150, when guaranteeing to buckle the design between implantation nature biological circuit contact site and the flexible detection portion and guaranteed that circuit contact site and skin surface are parallel to each other, the flexible detection portion is the slope is implanted in the skin, the slope is implanted and can be guaranteed to implant under equal degree of depth, strengthen the blood that the flexible detection portion implanted in the skin and can be some more deeply for the more accuracy of effect that detects.

Description of the drawings:

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic view of the split structure of the present invention;

in the drawings: 501. a blank electrode layer; 502. a working electrode layer; 503 a reference electrode layer; 504 a pair of electrode layers; 505. a circuit contact portion; 506. a flexible implantation detection section;

the specific implementation mode is as follows:

the technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like, indicate the orientation or positional relationship indicated based on the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.

In the present invention, unless otherwise expressly stated or limited, the terms "disposed," "mounted," "connected," and "fixed" are to be construed broadly, e.g., as meaning either a fixed connection or a removable connection; may be a mechanical connection; may be directly connected or indirectly connected through an intermediate. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature.

According to as shown in fig. 1-2, the utility model provides a technical scheme:

the utility model provides a novel implantation biosensor, is laminated structure, including blank electrode layer 501, working electrode layer 502, reference electrode layer 503 and counter electrode layer 504, blank electrode layer 501, working electrode layer 502, reference electrode layer 503 and counter electrode layer 504 all include circuit contact part 505 and flexible implantation detection portion 506, the transition connection part between circuit contact part 505 and the flexible implantation detection portion 506 is the design of buckling, and the present case has reduced the fore-and-aft length of implantation biosensor through such design of buckling for when the sensor was planted, need not to buckle, prolonged implantation biosensor's life.

Specifically, the bending angle B between the circuit contact part 505 and the flexible detection part 506 is 120-150 °, the bending design between the implanted biological circuit contact part 505 and the flexible detection part 506 is ensured, and meanwhile, when the circuit contact part 505 and the skin are parallel to each other, the flexible detection part 506 is obliquely implanted into the skin, and the oblique implantation can ensure that the blood implanted into the skin by the reinforced flexible detection part 506 is deeper under the same implantation depth, so that the detection effect is more accurate.

Specifically, the transitional connection part between the circuit contact 505 and the flexible detection part 506 is in a circular arc shape, so that the connection strength is ensured;

specifically, the thickness of the blank electrode layer 501, the working electrode layer 502, the reference electrode layer 503 and the counter electrode layer 504 after being laminated is 0.25-0.3 mm, so that the blank electrode layer can be maximally thin, the light volume is ensured, and the use is convenient.

Specifically, the width of the end part, far away from the circuit contact part 505, of the flexible detection part 506 is 0.07-0.14 mm, so that the wound area of skin is reduced, foreign body sensation is reduced, and the use comfort level is increased.

Specifically, the structural strength of the flexible implantation detection part 506 gradually decreases from the root connected to the circuit contact part 505 to the end far away from the circuit contact part 505, and the gradual decrease of the structural strength may be linear or stepped, so that the thickness of the flexible implantation detection part changes and becomes thinner when the flexible implantation detection part is far away from the root, and the stimulation to the tissue is further reduced, and similarly, the flexibility is increased when the thickness of the flexible implantation detection part is near the root, and the flexible implantation detection part can be prevented from breaking; because the stress of the sensor is larger and larger along with the gradual approach to the root, if the thickness of the sensor is made to be consistent, the sensor is easy to break or crack in order to avoid stimulating the subcutaneous tissue to be thinner, especially, the sensor is more stressed and more concentrated in stress and is also easier to break and crack in the place close to the root, and the measurement precision of the sensor can be influenced.

Specifically, the circuit contact portions 505 of the blank electrode layer 501, the working electrode layer 502, the reference electrode layer 503 and the counter electrode layer 504 are all rectangular parallelepipeds and have the same width, so that the overall aesthetic property is ensured, and the processing technology is simple.

Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and variations can be made in the embodiments or in part of the technical features of the embodiments without departing from the spirit and the scope of the invention.

Claims

1. The novel implantable biosensor is of a layered structure and is characterized by comprising a blank electrode layer (501), a working electrode layer (502), a reference electrode layer (503) and a counter electrode layer (504), wherein the blank electrode layer (501), the working electrode layer (502), the reference electrode layer (503) and the counter electrode layer (504) respectively comprise a circuit contact part (505) and a flexible implantation detection part (506), and a transition connection part between the circuit contact part (505) and the flexible implantation detection part (506) is of a bending design.

2. The novel implantable biosensor as claimed in claim 1, wherein the bending angle B between the circuit contact portion (505) and the flexible implantation detection portion (506) is 120 ° to 150 °.

3. The novel implantable biosensor as claimed in claim 1, wherein the transition connection portion between the circuit contact portion (505) and the flexible implant detection portion (506) is formed in a circular arc shape.

4. The novel implantable biosensor as claimed in claim 1, wherein the thickness of the blank electrode layer (501), the working electrode layer (502), the reference electrode layer (503) and the counter electrode layer (504) after lamination is 0.25-0.3 mm.

5. The novel implantable biosensor as claimed in claim 1, wherein the width of the end of the flexible implantation detection part (506) away from the circuit contact part (505) is 0.07-0.14 mm.

6. The novel implantable biosensor as claimed in claim 1, wherein the structural strength of the flexible implantation sensing portion (506) decreases gradually from the root portion connected to the circuit contact portion (505) to the end portion away from the circuit contact portion (505).

7. The novel implantable biosensor as claimed in claim 1, wherein the circuit contacts (505) of the blank electrode layer (501), the working electrode layer (502), the reference electrode layer (503) and the counter electrode layer (504) are all rectangular parallelepipeds and have the same width.