CN103750156B - Dried eucommia bark noodles and the application in prevention and therapy hypertension thereof - Google Patents

Dried eucommia bark noodles and the application in prevention and therapy hypertension thereof Download PDF

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Publication number
CN103750156B
CN103750156B CN201410029920.6A CN201410029920A CN103750156B CN 103750156 B CN103750156 B CN 103750156B CN 201410029920 A CN201410029920 A CN 201410029920A CN 103750156 B CN103750156 B CN 103750156B
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eucommia
bark
flour
water
extract
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CN103750156A (en
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于华忠
卜晓英
王亭
陈雁梅
董爱文
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Jishou University
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Jishou University
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10Cereal-derived products
    • A23L7/109Types of pasta, e.g. macaroni or noodles
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The object of the invention is to open one and effectively can utilize folium cortex eucommiae, low cost, be rich in Geniposidic acid, Aucubin isoreactivity material, also the nutriment such as amino acid, glucose is rich in, the vermicelli processing method of gutta-percha can be reduced again, and can be widely used in the hypertensive diet of prevention and therapy.Folium cortex eucommiae obtains ulmoprenol extract and bark of eucommia water extract through ethanolic solution and sour water lixiviate, and recycle water-soluble solution dry flour and form flour breast, the steps such as embedding, vacuum outgas, slaking, compressing tablet obtain dried eucommia bark noodles.Chlorogenic acid containing part in the vermicelli that the present invention produces, is conducive to the antiviral and diuresis of human body, is also conducive to the preservation of vermicelli simultaneously; Adopt ultrasonic process to be beneficial to active ingredient rapid osmotic in folium cortex eucommiae and, in starch network structure, more can be beneficial to the reservation of active ingredient; Adopt eucommia leaf extract to add in flour, gutta-percha to be removed in Bark of Eucommia Ulmoides completely on the impact of vermicelli.<pb pnum="1" />

Description

Dried eucommia bark noodles and the application in prevention and therapy hypertension thereof
Technical field
The invention belongs to natural products manufacture field, relate to the application of dried eucommia bark noodles in prevention and therapy hypertension, more particularly relate to a kind of manufacture craft and the application of dried eucommia bark noodles in prevention and therapy hypertension of dried eucommia bark noodles.
Background technology
The bark of eucommia is a kind of woody deciduous plant with multiple medicinal function, has high medical value, existing two thousand years history of being used as medicine, and " Shen agriculture book on Chinese herbal medicine warp " is listed in " top grade ", " thinking celestial " by name.Chemical composition mainly lignanoids, cyclenes ether mushroom glucoside, phenols, volatile oil, polysaccharide, amino acid, organic acid, deep and remote alcohol, phosphatide, flavones, vitamin, trace element and the gutta-percha etc. of the bark of eucommia.Wherein, lignanoids has Pinoresinol diglucoside, cloves lipidol diglucoside, olivil and the bark of eucommia element A, B etc.Pinoresinol diglucoside and cloves lipidol diglucoside, have two-way regulating function to animal blood pressure, cloves lipidol diglucoside also has enhancing memory capability, strengthens animal endurance, stabilizes calm, anti-oxidant, effect such as reduction cholesterol and neutral fat etc.: all nanmus acid of cyclenes ether mushroom glucoside has promotion choleresis and temporary hypotensive effect: Aucubin has stronger antibacterial action and obvious diuresis: asperuloside and ligustrin are the inhibitor of angiotensins and ring gland former times acid (cAMP); Chlorogenic acid has strong antibacterial action and adrenergic similar effect; Bark of eucommia each several part all containing abundant vitamin and β mono-carrotene, has delaying senility, strengthens the effect of immunity of organisms: eucommia bark polycose A with B has the Activation Activity to reticuloendothelial system identical with zymosan; Detect 17 kinds of free amino acids in Bark of Eucommia Ulmoides leaf, also isolate three crystallizations having and obviously promote the synthesis of DNA, protein and hypotensive effect, i.e. syringaresinol alcohol disaccharide glucoside, Geniposidic acid and Pinoresinol diglucoside.
Geniposidic acid has catharsis effect; Choleresis can be promoted; There is ACA; Can decline to animality ability, the growth of adrenal gland size that decrease of memory and pressure cause has protective effect; Antitumor activity.
Aucubin is one of effective active composition in the bark of eucommia, and all containing this composition in Bark of Eucommia Ulmoides, leaf and seed, in seed, content can, up to 19% ~ 23%, be one of bitter principle material of eucommia bark seed.In Bark of Eucommia Ulmoides and leaf, peach jaurel salidroside content has larger difference, folium cortex eucommiae is higher than Bark of Eucommia Ulmoides content, because cyclenes ether double bond character is active, Aucubin is easily by enzyme and acid hydrolysis, temperature is also very large on the impact of Aucubin antioxidation activity, therefore the content difference of Aucubin in fresh goods and dry product is also very large.
Chlorogenic acid be plant in aerobic respiration process, a kind of phenylpropanoids that the intermediate product through pentose phosphate pathway synthesizes, has very strong pharmacologically active, all has significant curative effect to digestive system, hematological system and genital system diseases.The discoveries such as Hem-merl, chlorogenic acid and derivative thereof are the specific inhibitors of G6P translocase system, contribute to the higher glycogen drainage rate that reduction non-insulin-dependent hyperpietic shows, demonstrating the good prospect of chlorogenic acid in treatment hypertension, is also the main active substances of anti-epidemic virus containing a large amount of chlorogenic acid isomers in folium cortex eucommiae.
The dry blowing method of publication number a kind of vermicelli that have been the Introduction To Cn Patent of CN102578177A and dry blowing vermicelli, comprise the following steps: (1) dry blowing: manufactured vermicelli are put in microwave device and heats dry blowing, vermicelli are heated to 50 DEG C ~ 80 DEG C, keep 1 hour ~ 35 hours, relative humidity remains on 60 ﹪ ~ 80 ﹪, described vermicelli are for hanging vermicelli or cutting off vermicelli in bulk or paper bag vermicelli or mould bag vermicelli, and the moisture content of vermicelli is 10 ﹪ ~ 16 ﹪; (2) cool tempering: the vermicelli after step (1) dry blowing are cooled to room temperature, cooldown rate is 2 DEG C/h ~ 30 DEG C/h, and relative humidity remains on 60 ﹪ ~ 80 ﹪, and the moisture content controlling vermicelli is less than or equal to 14.5 ﹪.Load in texture index during maximum load comparatively contrasts and improves 10 ﹪ ~ 200 ﹪, gluten network structure consolidation, the malleable of vermicelli strengthens, Cuisine loss rate comparatively contrasts and reduces 0.5 percentage point ~ 1.5 percentage points, and vermicelli mouthfeel is good, resistant to cook, save-resistant, the edible quality that tool is good, cooking performance and commodity effect, the inventive method is scientific and reasonable, simple, is applicable to industrial applications; The present invention adopts unconventional thinking, high temperature dry blowing process is carried out to manufactured vermicelli, improve the quality of vermicelli, particularly improve hardness and the toughness of vermicelli, reach sterilization and vermins-proof effect simultaneously, improve the shelf-life of product, when also can avoid directly adopting hyperthermia drying, occur the appearance of the quality problems such as noodle rupture, mouthfeel be not good enough.
Publication number be the Introduction To Cn Patent of CN102349553A a kind of health care coarse food grain flour, vermicelli and preparation technology thereof, comprise following raw material (by weight): (1) coarse cereals: wheat 60 ~ 70 parts, corn 4 ~ 6 parts, polished rice 4 ~ 6 parts and barley 4 ~ 6 parts; (2) auxiliary material: walnut 0.2 ~ 1 part, ox blood 0.1 ~ 0.8 part, goose blood 0.15 ~ 0.6 part, Chinese yam 0.1 ~ 0.6 part and the membrane of a chicken's gizzard 0.1 ~ 0.8 part.The auxiliary material of health care coarse food grain flour of the present invention comprises pig blood 0.1 ~ 0.8 part further, 0.1 ~ 0.6 part, auricularia auriculajudae, peanut 0.2 ~ 1 part, cassia seed 0.2 ~ 1 part.Coarse cereals also can comprise any mixture of any one or they being selected from sweet potato powder, lima bean, pea, soya bean, millet or Chinese sorghum, 8 ~ 12 parts.The invention discloses the preparation technology of aforementioned health care coarse food grain flour.Meanwhile, the invention discloses the obtained health care dried coarse grain noodles of aforementioned health care coarse food grain flour and preparation technology thereof.
Publication number be the Introduction To Cn Patent of CN102511728A a kind of purple potato vermicelli and manufacture method thereof, comprises according to the following compositions of weight fraction than configuration: raw material face: 78-84 part, purple sweet potato powder: 16-24 part, salt: 1.5-3 part, water: 10-15 part.The present invention can be added with further according to weight fraction chitin 0.2-0.8 part than configuration.Also can be added with further according to weight fraction micro-0.05-0.1 part than configuration.Can be added with further again according to weight fraction vegetable juice 5-10 part than configuration.Present invention process is simple, and obtained vermicelli are nutritious, useful to health, can be added with other nutritional labelings, is a kind of purple potato vermicelli of functional form enriching people's dietary requirements.
Publication number be the Introduction To Cn Patent of CN102511730A a kind of Konjak fine dried noodle and processing method thereof, each components in mass portion of Konjak fine dried noodle is: wheat flour is 94-96 part, and konjac glucomannan is 3-4 part, and egg is 1-2 part, edible salt is 0.6-1 part, dietary alkali is 0.1-0.2 part, appropriate water.The processing method of above-mentioned Konjak fine dried noodle, specific as follows: konjac glucomannan, dietary alkali are put into container simultaneously, add water and carry out stirring gelatinization, the time is 10-15 minute, obtains pasty state material; Wheat flour, appropriate water are stirred, the mass ratio of wheat flour and water is generally 5: 1; Then add the pasty state material of edible salt, egg juice, step (2), then stir 10-20 minute; By the dough rest after stirring, through rolling sheet, slitting, oven dry, crop, blocking, obtain Konjak fine dried noodle.Vermicelli mouthfeel of the present invention is good, chewiness, and have the health-care effects such as lipopenicillinase, hypotensive, appetizing, defaecation, beauty treatment, its processing method simple possible, can realize continuous prodution.
To be the Introduction To Cn Patent of CN102524667A a kind of has vermicelli for the treatment of diabetes and preparation method thereof for publication number, and comprise flour 10-91 part, root of kudzu vine 1-50 part, folium cortex eucommiae 1-50 part and Chinese cassia tree 0.1-2 part, its uniqueness of filling a prescription, raw material is easy to get; Also disclose the preparation method of these vermicelli; its preparation method is simple; do not need special process and equipment; obtained vermicelli instant; conventionally can cook according to taste; diabetes can be treated after edible; blood sugar decreasing effect is obvious; be with a wide range of applications; but wherein the Main Function of folium cortex eucommiae is hypoglycemic, and in the root of kudzu vine, the Flavonoid substances content such as Puerarin is very low, only has about 0.1%; and also can inactivation under hot conditions unprotect, therefore hypotensive effect is not obvious.
Publication number a kind of method making black bean vermicelli that has been the Introduction To Cn Patent of CN102550944A, comprises the following steps: step one, metering and face: all added by the supplementary material in batching and adjust in powder machine; Step 2, slaking: the dough of becoming reconciled is natural slaking 28-30 minute under about 25 DEG C room temperatures; Step 3, roll compacting: the good dough of slaking is in compound flaking machine, and roll compacting rotating speed is 10 revs/min, rolls thin rate 50%, and roll compacting becomes wearing of 3-4 millimeter; Step 4, slitting: roll compacting repeatedly, when to wear thickness be 1 millimeter, be printed as the noodles of 2 mm wides with strip-cutter; Step 5, oven dry of having one's hair trimmed: after being had one's hair trimmed by noodles, be placed in baking room to dry and can make black bean vermicelli in 5-6 hour.These vermicelli manufacture craft is simple, raw material is extensively easy to get, formula rationally, nutritious, instant, suitable for four seasons, without any side effects, improve protein and the lysine content of vermicelli, and it is plain to contain ginsenoside in Testa sojae atricolor, can promote human metabolism, dispelling fatigue is suitable for all kinds of crowd and eats.
To be the Introduction To Cn Patent of CN102150844A a kind of has vermicelli for the treatment of diabetes function and preparation method thereof for publication number, following method is adopted to make: the first step: take by weight: Buddha's hand 30 ~ 38 parts, Chinese yam 28 ~ 35 parts, bark of eucommia mulberry 15 ~ 20 parts, the fruit of Chinese wolfberry 28 ~ 35 parts, 10 ~ 15 parts, pumpkin, the Radix Astragali 10 ~ 12 parts, the wind-weed 5 ~ 8 parts, glutinous rehmannia 10 ~ 12 parts, American Ginseng 5 ~ 8 parts; Second step: said components raw material is mixed, boiling twice, add the water of 10 times of weight for the first time, decoct 2 hours, second time adds the water of 8 times of weight, decoct 1.5 hours, decoct extract for twice respectively with 160-180 mesh screen, it is 1.23 ~ 1.26g/cm3 that filtrate is concentrated into density, obtains medicinal extract, described medicinal extract and starch are mixed according to the ratio that ratio of weight and number is 1: 8 ~ 12, then adopts the vermicelli preparation technology of existing routine to make vermicelli.The present invention can nourishing pancreas islet cell, improves islet function, effectively controls the sugared index of life of food, reduces on an empty stomach and postprandial blood sugar, reduces the consumption for the treatment of diabetes medicament, improve the quality of living.
The Adding Way of publication number to be the Introduction To Cn Patent of CN101606654 a kind of during vermicelli produce farina and application, comprise the following steps: (1) prepares farina breast: with the dried potato starch of moisture content 12% for benchmark, dried potato starch 2 parts-30 parts is chosen by every 100 parts of flour, dried potato starch is added normal-temperature water and is dissolved into starch milk, the ratio of dried potato starch and normal-temperature water is 1: 0.5-1.5; (2) prepare pre-gelatinized potato starch to stick with paste: in step (1) gained starch milk, add 90 DEG C of-98 DEG C of boiling water, abundant stirring, form the Potato Starch Paste of clear viscous shape, be cooled to 45 DEG C-60 DEG C for subsequent use, the ratio of dried potato starch and boiling water is 1: 6-8; (3) dough is prepared: be added in dough mixing machine by step (2) gained Potato Starch Paste and flour, through stirring, being settled into dough.
The publication number curing process that to be the Introduction To Cn Patent of CN101606655 a kind of during vermicelli produce and ripening device used, dough sheet [2] is placed in heat and moisture preserving cover [1] interior slaking, it is characterized in that in maturing process, time controling was at 15 minutes-25 minutes, temperature controls at 25 DEG C-32 DEG C, relative humidity controls at 80%-90%, the described ripening device used conveyer comprising connection compound calender and continuous calendar, conveyer is arranged in frame [4], and be located in heat and moisture preserving cover [1], heat and moisture preserving cover is provided with warming and humidifying device in [1], dough sheet after overcuring, inner gluten desmachyme reaches stable state, there is flexibility, viscoplasticity and good ductility, be convenient to the processing of subsequent handling, warming and humidifying device in ripening device used is simple, and compared with the steam heating and humidifying produced with boiler, convenient operation and control, meanwhile, decreases the pollution to environment.
Publication number be the Introduction To Cn Patent of CN102132830A a kind of eucommia health-care dried noodles and processing method thereof, gets Bark of Eucommia Ulmoides or leaf, impurity elimination, cleaning, drying, after pulverizing, mix with salt, after being dissolved in water, then join in wheat flour, consist of wheat flour 93-99%, salt 0.5-1.5% and Bark of Eucommia Ulmoides or leaf powder 0.5-5.5%, and face, slaking, compressing tablet, slitting, dries, cut off, packaging.Achieve the health-care efficacy composition also having eaten Bark of Eucommia Ulmoides or leaf when edible eucommia health-care dried noodles, suitable lumbago due to the kidney deficiency, waist-leg weakness, fetal irritability, threatened abortion, low blood pressure and hypertension colony eat.This method does not carry out its active ingredient protection in preparation process, and step-down active ingredient complete deactivation under the high temperature conditions, only has chlorogenic acid to have amount of activated.
At present, the chemical composition of folium cortex eucommiae and the research of pharmacological action obtain remarkable progress, and are progressively applied to food preservative production.Chemical constitution study proves, containing higher nutritional labeling in folium cortex eucommiae, and the toxic component content such as gutta-percha are far below national standard; Pharmacological research proves, the bark of eucommia can promote the synthesis of animal protein, improve immune response ability and resistance against diseases, promotion cholesterol and lipid-metabolism etc.At present, there are reports as the application of anticorrisive agent in food production for Eucommia Leaf Powder, but due in folium cortex eucommiae in high temperature working processes easy in inactivation, very difficult farthest reservation chlorogenic acid isoreactivity material becomes the material that human body can directly utilize, if the content of product Content of Chlorogenic Acid isoreactivity material can be improved, to be conducive to improving body immunity, and reduce the mankind and to fall ill chance.The present invention makes full use of after starch at high temperature becomes pasty state, form network structure, be in network structure, after degassed by mixing its active ingredient rear with eucommia leaf extract, at high temperature effectively can prevent the inactivation of its active ingredient, retain the active ingredient of its folium cortex eucommiae as far as possible.
Summary of the invention
The object of the invention is to open one and effectively can utilize folium cortex eucommiae, low cost, be rich in Geniposidic acid, Aucubin isoreactivity material, also the nutriment such as amino acid, glucose is rich in, the vermicelli processing method of gutta-percha can be reduced again, and can be widely used in the hypertensive diet of prevention and therapy.
Therefore, the invention provides a kind of preparation method of dried eucommia bark noodles, and it is used for prevention and therapy hypertension, its step also comprises:
(1) folium cortex eucommiae extracts active ingredients and purifying: bark of eucommia tender leaf is carried out completing 2-3 minutes through tea drum fixation machine, after 40-50 DEG C of oven dry, about carrying out being crushed to 40 orders after the dry Bark of Eucommia Ulmoides of the weight such as interpolation again, add ethanolic solution and carry out lixiviate about 60min at 50-60 DEG C, ceramic membrane (filter opening is 0.45 μm) filters once, filtrate at 50 DEG C reduced pressure concentration original volume 1/4 concentrate I, in its concentrate I, add decolouring activated carbon carry out decolouring 20-25min, ceramic membrane (filter opening is 0.22 μm) filters and once obtains ulmoprenol extract, filter residue is added sour water at 50-60 DEG C and carries out lixiviate about 60min, ceramic membrane (filter opening is 0.45 μm) filters once, filtrate at 50 DEG C reduced pressure concentration original volume 1/4 concentrate II, in its concentrate II, add decolouring activated carbon carry out decolouring 20-30min, ceramic membrane (filter opening is 0.22 μm) filters and once obtains bark of eucommia water extract, be that bark of eucommia extract is for subsequent use after gained ulmoprenol extract and bark of eucommia water extract being carried out equal-volume mixing.
(2) dried eucommia bark noodles preparation: dry flour is added normal-temperature water and be dissolved into flour breast, the part by weight of dry flour and normal-temperature water is 1:1.6-2.5, prepared flour breast is heated to into about 85 DEG C, stir, form the flour paste of clear viscous shape, vacuum outgas be cooled to 40 DEG C for subsequent use, again institute's separation and purification being obtained bark of eucommia extract joins in flour paste, bark of eucommia flour pastel is obtained after stirring, add wheat flour again, proceed in dough mixing machine, add water to and make water content control at 40-50%, through stirring, be settled into dough, again Fruit storage 30min is carried out with behind face, slaking, compressing tablet, slitting, high temperature flash baking (42-48 DEG C) 40min, cut off, namely packaging obtains dried eucommia bark noodles,
In one embodiment, add the volume (L) of ethanolic solution in step (1) with the weight (kg) of folium cortex eucommiae than being 3-5:1, described ethanolic solution is 75-85% ethanol water.
In one embodiment, the aqueous hydrochloric acid solution of to be pH the be 2-3 of sour water described in step (1), 0.001-0.01mol/L aqueous hydrochloric acid solution, adds the amount (L) of sour water with the weight (kg) of filter residue than being 4-8:1.
In one embodiment, the amount (kg) adding decolouring activated carbon described in step (1) in its concentrate I is 2-5:100 with concentrate I volume (L) ratio.
In one embodiment, the amount (kg) adding decolouring activated carbon described in step (1) in its concentrate II is 3-8:100 with concentrate II volume (L) ratio.
In one embodiment, described in step (2), mixing time is 2-4min, and temperature is at 25-35 DEG C, and the rotating speed of dough mixing machine remains on 14r/min-16r/min; The dough uniform color of becoming reconciled, holds agglomerating, and loose during rubbing is graininess.
In one embodiment, adding the volume (L) of bark of eucommia extract described in step (2) with amount (kg) ratio of dry flour is 1-2:1.
In another embodiment, the amount (kg) adding wheat flour described in step (2) is 2-5:1 with dry flour (kg) ratio.
Technique effect:
1, under high temperature, aerobic conditions, chlorogenic acid, Geniposidic acid and Aucubin are oxidizable, but not easily oxidation Decomposition under anoxic conditions, but changing in solution ph also to make active material change, chlorogenic acid is more stable in acid condition, and Geniposidic acid is more stable in acid condition, and Aucubin is more stable in neutral conditions, various active material just can be made to be separated by flour gelatinization, make these materials be retained in the middle of the molecule of Fen, netted shallow lake as far as possible.
2, by flour embedding (wrapping up in) process, chlorogenic acid composition and the effect of the composition such as Geniposidic acid and Aucubin of institute's stripping after folium cortex eucommiae fragmentation can be reduced, remain the antihypertensive diuretic such as Geniposidic acid and Aucubin composition to the full extent, be conducive to health care.
3, the present invention is by the gelatinization of flour high temperature, form a large amount of network structures, be beneficial to the maximum reservation of bark of eucommia active material, and pertinent literature adopts the gelatinization of starch high temperature to be used to increase the elasticity of dough, we adopt in folium cortex eucommiae contains a small amount of gutta-percha, can reach the elasticity improving dough.
4, the chlorogenic acid containing part in the vermicelli produced of the present invention, is conducive to the antiviral and diuresis of human body, is also conducive to the preservation of vermicelli simultaneously.
5, adopt ultrasonic process to be beneficial to active ingredient rapid osmotic in folium cortex eucommiae and, in starch network structure, more can be beneficial to the reservation of active ingredient.
6, adopt eucommia leaf extract to add in flour, gutta-percha to be removed in Bark of Eucommia Ulmoides completely on the impact of vermicelli.
Detailed description of the invention
Further illustrate essentiality content of the present invention with embodiment of the present invention down, but do not limit the present invention with this.
Embodiment 1: the making of dried eucommia bark noodles
Bark of eucommia tender leaf is carried out completing 2-3 minutes through tea drum fixation machine, after 40-50 DEG C of oven dry, about carrying out being crushed to 40 orders after the dry Bark of Eucommia Ulmoides of the weight such as interpolation again, take 100kg, 80% ethanol water adding 400L carries out lixiviate about 60min at 50-60 DEG C, filter opening be the ceramic membrane filter of 0.45 μm once, filtrate at 50 DEG C reduced pressure concentration original volume 1/4 the concentrate I of 80L, in its concentrate I, add 2kg decolouring activated carbon carry out decolouring 20-25min, ceramic membrane (filter opening is 0.22 μm) filters and once obtains ulmoprenol extract, filter residue is carried out lixiviate about 60min at the 0.001-0.01mol/L aqueous hydrochloric acid solution that 50-60 DEG C adds 500L, ceramic membrane (filter opening is 0.45 μm) filters once, filtrate at 50 DEG C reduced pressure concentration original volume 1/4 concentrate II, in its concentrate II, add 5kg decolouring activated carbon carry out decolouring 20-30min, ceramic membrane (filter opening is 0.22 μm) filters and obtains bark of eucommia water extract, be that bark of eucommia extract is for subsequent use after gained ulmoprenol extract and bark of eucommia water extract being carried out equal-volume mixing.
Normal-temperature water 100kg dry flour being added 200L is dissolved into flour breast, prepared flour breast is heated to into about 85 DEG C, mixing time is 2-4min, temperature is at 25-35 DEG C, form the flour paste of clear viscous shape, vacuum outgas be cooled to 40 DEG C for subsequent use, again institute's separation and purification being obtained 120L bark of eucommia extract joins in flour pastel, bark of eucommia flour pastel is obtained after stirring, add 300kg wheat flour again, proceed in dough mixing machine, the rotating speed of dough mixing machine remains on 14r/min-16r/min, add water to and make water content control at 40-50%, through stirring, be settled into dough, the dough uniform color of becoming reconciled, hold agglomerating, loose during rubbing is graininess, again Fruit storage 30min is carried out with behind face, slaking, compressing tablet, slitting, high temperature flash baking (42-48 DEG C) 40min, cut off, namely packaging obtains dried eucommia bark noodles.
Comparative examples 1: the making of eucommia health-care dried noodles
Bark of eucommia tender leaf is carried out completing 2-3 minutes through tea drum fixation machine, after 40-50 DEG C of oven dry, about carrying out being crushed to 40 orders after the dry Bark of Eucommia Ulmoides of the weight such as interpolation again, a kind of processing method of eucommia health-care dried noodles is processed by the Introduction To Cn Patent that publication number is CN102132830A, obtains eucommia health-care dried noodles.
Embodiment 2: the rat of dried eucommia bark noodles feeds experiment---hypertensive rat model is set up
(1) adult SD rats (120-150g), cultivates under (25 ± 1 DEG C) ventilation condition, illumination 12h, dark 12h, and free choice feeding, standard are fed.
(2) Hypertensive Rats (RHR) induction: after anesthesia, prone position is fixed, the sandbag of lower abdominal pad one height about 2-3cm, cut off the hair of operating field, sterilization skin, cut skin to the 3rd lumbar vertebrae along midvertebral line from the 10th thoracic vertebrae, carefully kidney and surrounding tissue are peeled off at left side place, be separated the arteria renalis and vein, the arteria renalis is tied, last layering suture operation otch with line.The benzyl penicillin prevention of hypodermic injection 1-2 ten thousand unit is infected.About there is continuation hypertension through 7 days rats.
(3) animal grouping: 42 RHR rats are divided into 7 groups at random, often organizes 6.Blank group: give to feed normal diet, and give distilled water 5ml gavage 1 time/d; Negative control group: give to feed normal diet, the mixed common vermicelli of 5g/d, and give distilled water 5ml gavage 1 time/d; Low dosage dried eucommia bark noodles group: give to feed normal diet, mixed dried eucommia bark noodles 5g/d, and give distilled water 5ml gavage 1 time/d; Middle dosage dried eucommia bark noodles group: give to feed normal diet, mixed dried eucommia bark noodles 10g/d, and give distilled water 5ml gavage 1 time/d; High dose dried eucommia bark noodles group: give to feed normal diet, mixed dried eucommia bark noodles 20g/d, and give distilled water 5ml gavage 1 time/d; Nifedipine group: give to feed normal diet, and give 10mg/kg/d+ distilled water 5ml gavage 1 time/d; Middle dosage comparative examples group: give to feed normal diet, by the mixed eucommia health-care dried noodles 10g/d that comparative examples 1 is obtained, and gives distilled water 5ml gavage 1 time/d.Raise to the execution of 8 monthly ages.
(4) blood pressure measurement: often organize rat in test start time and the 2nd week, the 4th week, the 8th week, the 12nd week measurement mouse tail blood pressure (systolic pressure).Adopt rat tail sphygmomanometer, rat preheating 40 DEG C (hair dryer preheating), measures mouse tail blood pressure under waking state, surveys once, totally 3 times, average every 10m in.
Table 1 dried eucommia bark noodles is on the impact of SHR rat blood pressure

Claims (5)

1. a preparation method for dried eucommia bark noodles, its step comprises:
(1) folium cortex eucommiae extracts active ingredients and purifying: bark of eucommia tender leaf is carried out completing 2-3 minutes through tea drum fixation machine, after 40-50 DEG C of oven dry, carry out again after the dry Bark of Eucommia Ulmoides of the weight such as interpolation being crushed to 40 orders, add 75-85% ethanol water and carry out lixiviate 60min at 50-60 DEG C, filter opening be the ceramic membrane filter of 0.45 μm once, filtrate at 50 DEG C reduced pressure concentration original volume 1/4 concentrate I, in its concentrate I, add decolouring activated carbon carry out decolouring 20-25min, filter opening is that the ceramic membrane filter of 0.22 μm once obtains ulmoprenol extract, filter residue is added sour water at 50-60 DEG C and carries out lixiviate 60min, filter opening be the ceramic membrane filter of 0.45 μm once, filtrate at 50 DEG C reduced pressure concentration original volume 1/4 concentrate II, in its concentrate II, add decolouring activated carbon carry out decolouring 20-30min, filter opening is that the ceramic membrane filter of 0.22 μm once obtains bark of eucommia water extract, be that bark of eucommia extract is for subsequent use after gained ulmoprenol extract and bark of eucommia water extract being carried out equal-volume mixing, wherein add the volume L of 75-85% ethanol water with the weight kg of folium cortex eucommiae than being 3-5:1,
(2) dried eucommia bark noodles preparation: dry flour is added normal-temperature water and be dissolved into flour breast, the part by weight of dry flour and normal-temperature water is 1:1.6-2.5, prepared flour breast is heated to 85 DEG C, stir, form the flour paste of clear viscous shape, vacuum outgas be cooled to 40 DEG C for subsequent use, again institute's separation and purification being obtained bark of eucommia extract joins in flour paste, wherein additional proportion is 1-2:1 by the volume L of bark of eucommia extract and the amount kg of dry flour, bark of eucommia flour pastel is obtained after stirring, add wheat flour again, proceed in dough mixing machine, add water to and make water content control at 40-50%, through stirring, be settled into dough, again Fruit storage 30min is carried out with behind face, slaking, compressing tablet, slitting, high temperature flash baking, 40min is dried at 42-48 DEG C, cut off, namely packaging obtains dried eucommia bark noodles, the amount kg and the dry flour weight kg ratio that wherein add wheat flour are 2-5:1.
2. method according to claim 1, the wherein aqueous hydrochloric acid solution of to be pH the be 2-3 of sour water described in step (1), 0.001-0.01mol/L aqueous hydrochloric acid solution, adds the amount L of sour water and the weight kg of filter residue than being 4-8:1.
3. method according to claim 1, the amount kg wherein adding decolouring activated carbon described in step (1) in its concentrate I is 2-5:100 with concentrate I volume L ratio.
4. method according to claim 1, the amount kg wherein adding decolouring activated carbon described in step (1) in its concentrate II is 3-8:100 with concentrate II volume L ratio.
5. method according to claim 1, wherein described in step (2), mixing time is 2-4min, and temperature is at 25-35 DEG C, and the rotating speed of dough mixing machine remains on 14r/min-16r/min; The dough uniform color of becoming reconciled, holds agglomerating, and loose during rubbing is graininess.
CN201410029920.6A 2014-01-22 2014-01-22 Dried eucommia bark noodles and the application in prevention and therapy hypertension thereof Expired - Fee Related CN103750156B (en)

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CN109363042A (en) * 2018-12-26 2019-02-22 陕西天承生物科技股份有限公司 A kind of preparation method of high-quality Cortex Eucommiae leaf beverage concentration prime cement
CN109393485A (en) * 2018-12-26 2019-03-01 陕西天承生物科技股份有限公司 A kind of preparation method of high-quality folium cortex eucommiae extract powder
CN113498821A (en) * 2021-07-21 2021-10-15 珂美生物科技(长沙)有限公司 Black coffee solid beverage containing eucommia ulmoides extract and having no influence on sleep and preparation method thereof

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