CN103735600B - A kind of health product - Google Patents
A kind of health product Download PDFInfo
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- CN103735600B CN103735600B CN201310692618.4A CN201310692618A CN103735600B CN 103735600 B CN103735600 B CN 103735600B CN 201310692618 A CN201310692618 A CN 201310692618A CN 103735600 B CN103735600 B CN 103735600B
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Abstract
A kind of health product, these health product are become to be grouped into by following crude drug: Semen Vaccariae, 75 ~ 95 weight portions; Radix Angelicae Pubescentis, 5 ~ 25 weight portions.These health product can also form for above-mentioned component extract and food adjuvant.Health product of the present invention effectively can be removed cell precipitation thing, be free from side effects, the unique effects of skin moistening skin care, slow down aging.Long-term drink, can Yin Yang balancing, building body, life lengthening.
Description
Technical field
The present invention relates to a kind of health product, be specifically related to have the health product of effect of effectively removal cell precipitation thing, skin moistening skin care, slow down aging.
Background technology
Aging is that body declines and disorderly general performance in degeneration physiological function in period, is irreversible life process.Human body is got up by cell tissue, composition cell chemical substance be constantly subject to the impact of internal and external environment at the volley and damage, cause function degeneration decline and aging.Free radical and mankind's various diseases have close relationship, if interior free yl is too much, then can cause protein, nucleic acid denaturation, cause biological cells and tissues organ injury, bring out various pathological changes, accelerate body aging, simultaneously, free radical is excessive is also cause naturally aging of skin and cause aging main cause, reduces the generation of free radical and removes the effective ways that aging metabolite has become current delaying human body and skin aging.
The aging of cell and death are metabolic natural phenomenas.Moisture minimizing, age pigment---a series of changes such as the accumulation of fat brown pigment, enzymatic activity reduction, metabolic rate slack-off cell induration is there will be during cell ageing.Products of cellular metabolism build up to a certain amount of after can endanger cell, cause aging, the deposition of mammal lipofuscin is a typical example, lipofuscin is the huge cross-linking agent that some long-life protein and DNA, the condensation of lipid covalency are formed, secondary lysosome is the place forming lipofuscin, lipofuscin is the metabolite of radical reaction in body cell, and being has distinctive material in cellular senescence process, and in histoorgan, lipofuscin generation increase is one of aging mark.Free radical makes lipid peroxidation enzyme be decomposed to form end product malonaldehyde, and malonaldehyde is very live crosslinked matter, peptide class, the contaminated with lipid formation flaggy shape lipofuscin shelled.Along with the increase at age, the ability getting rid of free radical in body declines, and lipofuscin gathers in liver, skin and other tissue.When most of space accumulation lipofuscin of histiocyte endochylema, nucleus, organelle compressive deformation, affect its homergy function.Lipofuscin, after skin accumulation too much, namely combines together with some enzyme and makes enzyme deactivation, making cellularity generation degenerative change, accelerates ageing processes of skin, can make skin darkening (senile plaque), coarse and occur chloasma.When lipofuscin is after liver accumulation too much, the same ageing process accelerating liver, affects the normal physiological function of liver.
Chloasma belongs to traditional Chinese medical science chloasma, it is the dermatosis that a kind of facial area occurs that limitation is filbert or brown pigment is calm, skin lesion is yellowish-brown or dark brown patch, often be symmetrically distributed in cheekbone portion, face, buccal, become buttferfly-type, or involve forehead, nose, mouth week and chin portion be irregularly shaped, be apt to occur in young and middle-aged women.Current research thinks that the generation of chloasma is relevant with endocrine regulation, and there are some researches prove that estrogen can stimulation melanin emiocytosis melanin granule, and progestogen can promote the transhipment of melanosome and increase melanin amount, finally cause pigmentation.The cause of disease of chloasma is except outside the Pass having with endocrine regulation, sun exposure is also a key factor, and after transition light irradiates, chloasma can increase the weight of, and avoids Exposure to Sunlight that chloasma can be made to alleviate and even disappear, long term ultraviolet irradiates especially ultraviolet B radiation can make melanocyte breed, and melanin amount increases.
Due to lipofuscin compact structure, can not be thoroughly hydrolyzed, can not discharge cell again, result increases at intracellular deposits, and the material exchange of this precipitate block cell and signal transmission, finally cause cell ageing.Current health promoting beverage is for effectively removing this precipitate, and slow down aging, does not have good effect.
Summary of the invention
The object of this invention is to provide a kind of health product with effect of effectively removal cell precipitation thing, skin moistening skin care, slow down aging.
For achieving the above object, the present invention by the following technical solutions: a kind of health product, these health product are made up of the crude drug of following weight proportion: Semen Vaccariae, 75 ~ 95 weight portions; Radix Angelicae Pubescentis, 5 ~ 25 weight portions.
Health product described above, preferably, described health product are made up of the crude drug of following weight proportion: Semen Vaccariae, 80 weight portions; Radix Angelicae Pubescentis, 20 weight portions.
A kind of health product, these health product are made up through the extract of extraction and isolation of crude drug component described above.
Health product as above, preferably, the extract extraction separation method of described crude drug is: the crude drug getting recipe quantity, is ground into coarse powder, mix homogeneously, with 3 ~ 10 times amount soak by water or soak extraction 1 ~ 5 time, filters, gets filtrate, concentrate and get final product.
A kind of health product, these health product are made up of health product as above and food adjuvant.
Health product as above, preferably, the dosage form of described health product is any one in powder, powder, tablet, granule, decoction, oral liquid, sweet mastic, honeydew, beverage or tea bag preparation.
Health product described above, preferably, the preparation method of described powder or tea bag preparation is: take described crude drug, is ground into 60 ~ 80 order powderies, mix homogeneously, loads in sterilising filtration tea bag or sterilizing bag after sterilization, and sealing is preserved.
Beneficial effect of the present invention is: having of health product of the present invention is effectively removed cell precipitation thing, is free from side effects, skin moistening skin care, slow down aging, adjustment health, and relieving stress, treatment nephritis, prostatitis etc. have unique effects.Long-term drink, can Yin Yang balancing, building body, life lengthening.
Detailed description of the invention
Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.
Preparing the method for the preparation of health product of the present invention, can be the common method in techniques well known, and the preparation method of conventional formulation can see formulation texts or disclosed technical information.During as made oral liquid, decoction, can be that extracting liquid filtering is concentrated into finite concentration by described crude drug after water boiling and extraction or soak extraction or seepage pressure effects, after adding a certain amount of correctives, antiseptic, suspending agent or cosolvent, can obtain.These excipient added, be receptible excipient in health food or medicine, these excipient are that those skilled in the art can easily select from corresponding pharmaceutical adjunct.
When crude drug of the present invention is made tablet, granule, capsule, can be by described crude drug after water boiling and extraction or soak extraction or seepage pressure effects, gained extracting solution, after concentrate drying, adds appropriate filler, binding agent soft material, then granulate, can granule be obtained; After directly can being incapsulated by granule or directly being incapsulated by concentrated for extraction medicated powder, capsule can be obtained; After the granule obtained adds a certain amount of fluidizer, tabletted, can obtain tablet.
These different dosage forms above-mentioned, for a person skilled in the art, when not requiring specific condition, common preparation formulation easily prepares.
Crude drug of the present invention is Semen Vaccariae, Radix Angelicae Pubescentis.
Semen Vaccariae is the dry mature seed of Vaccaria segetalis (Vaccariasegetalis (Neck.) Garcke).Its different name for do not stay row, king unpopular, prohibit palace flower, cut gold grass, Herba Clematidis Huchouensis careless, golden small cup Yin Tai, Mai Lanzi.Aboundresources, main product in Hebei, Shandong, Liaoning, the ground such as Heilungkiang, maximum with Hebei output.Semen Vaccariae Drug Storage, flat, enter liver, stomach warp, mainly containing triterpene saponin, flavonoid glycoside, cyclic peptide, lipoid and fatty acid, the compositions such as monosaccharide, there is effect that promoting the circulation of blood is stimulated the menstrual flow, expedited the emergence of stimulating milk secretion, detumescence sore, be clinically used for the symptoms such as women's amenorrhea, galactostasis, difficult labour, stranguria with blood.
The dry root that Radix Angelicae Pubescentis (Radixangelicaepubescentis) is samphire Angelica pubescens, main product in Sichuan, Hubei, the ground such as Anhui.Radix Angelicae Pubescentis acrid in the mouth, hardship, tepor, returns liver, kidney, urinary bladder channel, main containing Coumarins, volatile oil, and a small amount of steroidal and carbohydrate content, its function expelling wind and removing dampness, dispersing cold for relieving pain, be mainly used in the diseases such as treatment anemofrigid-damp arthralgia, soreness of waist and knee joint, few cloudy volt wind headache, headache toothache.Radix Angelicae Pubescentis begins to be loaded in " Dragon Lord book on Chinese herbal medicine warp ", and being listed in top grade, is the key medicine for the treatment of rheumatic arthralgia since ancient times.
Below exemplify the present invention at the specific embodiment for effect in scavenger cell deposit (such as lipofuscin), slow down aging.
Embodiment 1 health product of the present invention are on the impact of skin and liver lipofuscin level
Experiment material: Wistar old rats (20-22 monthly age) 30, male and female half and half, body weight (450 ± 20) g; 4 ~ 6 months old rats 10, as green grass or young crops matched group in age, provide by Medical School of Peking University's animal feeding center.
Lipofuscin measures test kit: Nanjing is built up Bioengineering Research Institute and bought.
Health product A: take Semen Vaccariae 8g, Radix Angelicae Pubescentis 2g, is ground into coarse powder, with 5 times amount soak by water twice, filters, gets filtrate, be concentrated into 10ml;
Health product B: take Semen Vaccariae 8g, Radix Angelicae Pubescentis 2g, is ground into fine powder, mix homogeneously, with 10 times amount water soaking 8 hours, filters, gets filtrate, be concentrated into 10ml.
Get old rats 30, be divided into aged controls group (gavage normal saline) at random, (gavage only gives 0.5ml/ to health product A group, be equivalent to 1g crude drug amount/kg rat), (gavage gives 0.5ml/ only to health product B group, be equivalent to 1g crude drug amount/kg rat), 4 ~ 6 months old rats 10 are as blue or green matched group in age (gavage normal saline), administration 7 weeks, administration every day 1 time.Put to death animal in the 8th week the 1st day, get skin of back (unhairing) and liver appropriate, make the tissue homogenate of 10% respectively, get supernatant for subsequent use, by the operation of test kit description, measure lipofuscin content, experimental result is in table 1.
Table 1 health product of the present invention are to the change (X ± s) of rat skin and liver lipofuscin content
| Group | Liver | Skin |
| Aged controls group | 38.272±14.316 | 10.475±1.824 |
| Green grass or young crops matched group in age | 27.221±13.079 | 5.104±1.120 |
| Health product A group | 28.289±15.362 ** | 6.478±1.392 ** |
| Health product B group | 29.407±14.118 ** | 6.847±1.401 ** |
Compared with aged controls group,
*p<0.01.
From table 1, aged controls group rat liver and skin lipofuscin content are obviously higher than green grass or young crops matched group in age, after aged controls group rat takes health product of the present invention, the old rats group low (P<0.01) that its liver and skin lipofuscin level all will not taken, points out health product of the present invention to have the effect reducing aging rats liver and skin lipofuscin level.
The clinical therapeutic efficacy of the tea bag preparation of embodiment 2 health product of the present invention is observed
Take Semen Vaccariae 8g, Radix Angelicae Pubescentis 2g, pulverize, cross 60 mesh sieves, mix homogeneously, after disinfection by ultraviolet light, load in tea bag, sealing, obtains tea bag preparation.The method of making tea brews routinely, when tea-drinking use, every day potion.Model case:
1. Hu XX, female, 55 years old, there was obvious dark brown senile plaque in face, and take this tea bag preparation 2 months, senile plaque is obviously desalinated.
2. Lee XX, female, 62 years old, depression, face jaundice, had chloasma, and when tea-drinking tea bag preparation 4 months, chloasma be can't see substantially, and the mental status oneself feels very good.
3. king XX, female, 45 years old, suffers from climacteric syndrome, and mood is irritated, and insomnia, take tea bag preparation of the present invention 1 month, symptom disappears substantially.
4. Lee present inventor XX, man 74 years old, long-term as tea-drinking the present invention, face is without senile plaque, energetic.
5. an XX, female, 35 years old, complexion was turned to be yellow, and QI and blood is obstructed, and take tea bag preparation of the present invention 1 month, successful is got better.
6. room XX, man, 48 years old, carcinoma of prostate, urinated uneasy, took tea bag preparation of the present invention, and 1 month takes effect, unobstructed micturition.
7. an XX, man 56 years old, nephritis, urinates uneasy, takes tea bag preparation of the present invention, and 10 days take effect.
Claims (7)
1., for removing health product for cell precipitation thing skin moistening skin care slow down aging, it is characterized in that, described health product are made up of the crude drug of following weight proportion: Semen Vaccariae, 75 ~ 95 weight portions; Radix Angelicae Pubescentis, 5 ~ 25 weight portions.
2. health product as claimed in claim 1, it is characterized in that, described health product are made up of the crude drug of following weight proportion: Semen Vaccariae, 80 weight portions; Radix Angelicae Pubescentis, 20 weight portions.
3. for removing health product for cell precipitation thing skin moistening skin care slow down aging, it is characterized in that, described health product are made up of the extract of the crude drug described in claim 1 or 2 through extraction and isolation.
4. health product as claimed in claim 3, it is characterized in that, the extract extraction separation method of described crude drug is: the crude drug getting recipe quantity, be ground into coarse powder, mix homogeneously, with 3 ~ 10 times amount soak by water or soak extraction 1 ~ 5 time, filter, get filtrate, concentrate and get final product.
5. for removing health product for cell precipitation thing skin moistening skin care slow down aging, it is characterized in that, described health product are made up of the health product described in any one of claim 1-4 and food adjuvant.
6. health product as claimed in claim 5, is characterized in that, the dosage form of described health product is any one in powder, powder, tablet, granule, decoction, oral liquid, sweet mastic, honeydew, beverage or tea bag preparation.
7. health product as claimed in claim 6, it is characterized in that, the preparation method of described powder or tea bag preparation is: take described crude drug, be ground into 60 ~ 80 order powderies, mix homogeneously, loads in sterilising filtration tea bag or sterilizing bag after sterilization, and sealing is preserved.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310692618.4A CN103735600B (en) | 2013-12-17 | 2013-12-17 | A kind of health product |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310692618.4A CN103735600B (en) | 2013-12-17 | 2013-12-17 | A kind of health product |
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| Publication Number | Publication Date |
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| CN103735600A CN103735600A (en) | 2014-04-23 |
| CN103735600B true CN103735600B (en) | 2016-04-13 |
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| CN201310692618.4A Expired - Fee Related CN103735600B (en) | 2013-12-17 | 2013-12-17 | A kind of health product |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106616978A (en) * | 2016-11-25 | 2017-05-10 | 河池市农业科学研究所 | Human body health-care product and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1054517C (en) * | 1993-07-07 | 2000-07-19 | 曹斌 | Zhenlongyin health-care wine |
| CN102430099B (en) * | 2012-01-04 | 2013-05-22 | 揭静华 | Life-prolonging essence |
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Granted publication date: 20160413 Termination date: 20171217 |