CN103735600A - Healthcare product - Google Patents
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- CN103735600A CN103735600A CN201310692618.4A CN201310692618A CN103735600A CN 103735600 A CN103735600 A CN 103735600A CN 201310692618 A CN201310692618 A CN 201310692618A CN 103735600 A CN103735600 A CN 103735600A
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Abstract
The invention discloses a healthcare product which consists of the following raw medicine components in parts by weight: 75-95 parts of cowherb seed and 5-25 parts of radix angelicae pubescentis. The healthcare product also can consist of the extracts of the components and food accessories. The healthcare product disclosed by the invention can be used for effectively removing cell precipitate without side effect, and has unique functions of moistening skin and beautifying the appearance and delaying senescence. After long-time drinking, the healthcare product can be used for balancing the yin and yang, building the body and prolonging life.
Description
Technical field
The present invention relates to a kind of health product, be specifically related to have the health product of the effect of effective removal cell precipitation thing, skin moistening skin care, slow down aging.
Background technology
Aging is that body declines and disorderly general performance in degeneration physiological function in period, is irreversible life process.Human body is got up by cell tissue, and the chemical substance that forms cell is constantly subject to the impact of internal and external environment at the volley and damages, and causes function degeneration to decline and aging.Free radical and mankind's various diseases have close relationship, if interior free yl is too much, can cause protein, nucleic acid denaturation, cause cell and injuries of tissues and organs, bring out various pathological changes, accelerate body aging, simultaneously, free radical is excessive is also to cause naturally aging of skin and cause aging main cause, reduces the generation of free radical and removes the effective ways that aging metabolite has become current delaying human body and skin aging.
The aging of cell and death are metabolic natural phenomenas.During cell ageing, there will be moisture minimizing, age pigment---a series of variations such as the accumulation of fat brown pigment, enzymatic activity reduction, the slack-off cell sclerosis of metabolic rate.Products of cellular metabolism build up to a certain amount of after can harm cell, cause aging, the deposition of mammal lipofuscin is a typical example, lipofuscin is the huge cross-linking agent that some long-life protein and DNA, the condensation of lipid covalency form, secondary lysosome is the place that forms lipofuscin, lipofuscin is the metabolite of radical reaction in body cell, is in cell ageing process, to have distinctive material, and in histoorgan, lipofuscin generation increase is one of aging sign.Free radical makes lipid peroxidation enzyme be decomposed to form end product malonaldehyde, and malonaldehyde is crosslinked matter, peptide class, the contaminated with lipid formation flaggy shape lipofuscin of very living and shelling.Along with the increase at age, the ability of getting rid of free radical in body declines, and lipofuscin gathers in liver, skin and other tissue.When lipofuscin is accumulated in most of space of histiocyte endochylema, nucleus, organelle compressive deformation, affect its homergy function.Lipofuscin after skin accumulation too much, together with some enzyme in conjunction with and make enzyme deactivation, make cellularity generation degenerative change, accelerate ageing processes of skin, can make skin darkening (senile plaque), coarse and occur chloasma.When lipofuscin is after liver accumulation too much, accelerate equally the ageing process of liver, affect the normal physiological function of liver.
Chloasma belongs to traditional Chinese medical science chloasma, that the dermatosis that limitation is filbert or brown pigment is calm appears in a kind of facial area, skin lesion is yellowish-brown or dark brown patch, often be symmetrically distributed in face cheekbone portion, buccal, become buttferfly-type, or involve forehead, nose, mouthful week and chin portion and be irregularly shaped, be apt to occur in young and middle-aged women.At present research thinks that the generation of chloasma is relevant with endocrine regulation, and there are some researches prove that estrogen can stimulation melanin emiocytosis melanin granule, and progestogen can promote transhipment and the increase melanin amount of melanosome, finally cause pigmentation.The cause of disease of chloasma is except outside the Pass having with endocrine regulation, sun exposure is also a key factor, and after transition irradiate light, chloasma can increase the weight of, and avoids Exposure to Sunlight can make chloasma alleviate and even disappear, long-term ultraviolet radiation especially ultraviolet B radiation can make melanocyte propagation, and melanin amount increases.
Due to lipofuscin compact structure, can not be thoroughly hydrolyzed, can not discharge cell again, result deposits and increases in cell, and the material exchange of this precipitate block cell and signal transmission, finally cause cell ageing.Current health promoting beverage is for this precipitate of effective removal, and slow down aging, does not have good effect.
Summary of the invention
The object of this invention is to provide a kind of health product with the effect of effective removal cell precipitation thing, skin moistening skin care, slow down aging.
For achieving the above object, the present invention by the following technical solutions: a kind of health product, these health product are comprised of the crude drug of following weight proportion: Semen Vaccariae, 75～95 weight portions; Radix Angelicae Pubescentis, 5～25 weight portions.
Health product as mentioned above, preferably, described health product are comprised of the crude drug of following weight proportion: Semen Vaccariae, 80 weight portions; Radix Angelicae Pubescentis, 20 weight portions.
Health product, these health product are made through extracting separated extract by crude drug component as mentioned above.
Health product as above, preferably, the extract extraction separation method of described crude drug is: get the crude drug of recipe quantity, be ground into coarse powder, mix homogeneously, decocts or soak and extract 1～5 time with 3～10 times of water gagings, filters, and gets filtrate, concentrates and get final product.
Health product, these health product are comprised of with adjuvant health product as above and food.
Health product as above, preferably, the dosage form of described health product is any one in powder, powder, tablet, granule, decoction, oral liquid, sweet mastic, honeydew, beverage or tea bag preparation.
Health product as mentioned above, preferably, the preparation method of described powder or tea bag preparation is: take described crude drug, be ground into 60～80 order powderies, mix homogeneously packs in sterilising filtration tea bag or sterilizing bag after sterilization, sealing is preserved.
Beneficial effect of the present invention is: the thering is effective removal cell precipitation thing, be free from side effects of health product of the present invention, and skin moistening skin care, slow down aging, adjusting health, relieving stress, treatment nephritis, prostatitis etc. have unique effects.Long-term drink, can Yin Yang balancing, building body, life lengthening.
The specific embodiment
Following examples are used for illustrating the present invention, but are not used for limiting the scope of the invention.
The method of the preparation of preparation health product of the present invention, can be the common method in techniques well known, and the preparation method of conventional formulation can be referring to preparation textbook or disclosed technical information.As while making oral liquid, decoction, can be through water boiling and extraction or soak and extract or after percolation extracts, extracting liquid filtering is concentrated into finite concentration, adds after a certain amount of correctives, antiseptic, suspending agent or cosolvent, can obtain by described crude drug.These excipient that add, are receptible excipient in health food or medicine, and these excipient are that those skilled in the art can easily select from corresponding pharmaceutical adjunct.
When crude drug of the present invention is made to tablet, granule, capsule, can be through water boiling and extraction or soak to extract or after percolation extracts, gained extracting solution, after concentrate drying, adds appropriate filler, binding agent soft material processed by described crude drug, then granulate, can obtain granule; After granule directly can being incapsulated or the concentrated medicated powder of extraction directly being incapsulated, can obtain capsule; Resulting granule adds after a certain amount of fluidizer, and compacting in flakes, can obtain tablet.
Above-mentioned these different dosage forms, for a person skilled in the art, in the situation that not requiring specific condition, common preparation formulation easily prepares.
Crude drug of the present invention is Semen Vaccariae, Radix Angelicae Pubescentis.
Semen Vaccariae is the dry mature seed of Vaccaria segetalis (Vaccaria segetalis (Neck.) Garcke).Its different name is gone for not staying, king is unpopular, prohibit palace spends, cuts gold grass, Herba Clematidis Huchouensis careless, golden small cup Yin Tai, Mai Lanzi.Aboundresources, main product in Hebei, the ground such as Shandong, Liaoning, Heilungkiang, maximum with Hebei output.Semen Vaccariae Drug Storage, flat, enter liver, stomach warp, mainly contain triterpene saponin, flavonoid glycoside, cyclic peptide, lipoid and fatty acid, the compositions such as monosaccharide, there is promoting the circulation of blood and stimulate the menstrual flow, expedite the emergence of the effect of stimulating milk secretion, detumescence sore, the clinical symptoms such as women's amenorrhea, galactostasis, difficult labour, stranguria with blood that are used for.
Radix Angelicae Pubescentis (Radix angelicae pubescentis) is the dry root of samphire Angelica pubescens, main product in Sichuan, the ground such as Hubei, Anhui.Radix Angelicae Pubescentis acrid in the mouth, hardship, tepor, returns liver, kidney, urinary bladder channel, mainly contain Coumarins, volatile oil, and a small amount of steroidal and carbohydrate content, its function expelling wind and removing dampness, dispersing cold for relieving pain, be mainly used in treating the diseases such as anemofrigid-damp arthralgia, soreness of waist and knee joint, few cloudy volt wind headache, headache toothache.Radix Angelicae Pubescentis begins to be loaded in < < Dragon Lord book on Chinese herbal medicine through > >, is listed in top gradely, is the key medicine for the treatment of rheumatic arthralgia since ancient times.
Below exemplify the present invention at the specific embodiment in effect aspect scavenger cell deposit (such as lipofuscin), slow down aging.
The impact of embodiment 1 health product of the present invention on skin and liver lipofuscin level
Experiment material: 30 of Wistar old rats (20-22 monthly age), male and female half and half, body weight (450 ± 20) g; 4～6 10 of months old rats, as green grass or young crops matched group in age, provide by Medical School of Peking University's animal feeding center.
Lipofuscin is measured test kit: Nanjing is built up Bioengineering Research Institute and bought.
Health product A: take Semen Vaccariae 8g, Radix Angelicae Pubescentis 2g, is ground into coarse powder, decocts twice with 5 times of water gagings, filters, and gets filtrate, is concentrated into 10ml;
Health product B: take Semen Vaccariae 8g, Radix Angelicae Pubescentis 2g, is ground into fine powder, mix homogeneously, soaks 8 hours with 10 times of water gagings, filters, and gets filtrate, is concentrated into 10ml.
Get 30 of old rats, (gavage only gives 0.5ml/ to be divided at random aged matched group (gavage equivalent normal saline), health product A group, be equivalent to 1g crude drug amount/kg rat), (gavage gives 0.5ml/ only to health product B group, be equivalent to 1g crude drug amount/kg rat), 4～6 10 of months old rats are as blue or green matched group in age (gavage equivalent normal saline), administration 7 weeks, administration every day 1 time.In the 8th week the 1st day, put to death animal, get skin of back (unhairing) and liver appropriate, make respectively 10% tissue homogenate, get supernatant standby, by the operation of test kit description, measure lipofuscin content, experimental result is in Table 1.
The variation (X ± s) of table 1 health product of the present invention to rat skin and liver lipofuscin content
| Group | Liver | Skin |
| Aged matched group | 38.272±14.316 | 10.475±1.824 |
| Green grass or young crops matched group in age | 27.221±13.079 | 5.104±1.120 |
| Health product A group | 28.289±15.362 ** | 6.478±1.392 ** |
| Health product B group | 29.407±14.118 ** | 6.847±1.401 ** |
Compare with aged matched group,
*p<0.01.
From table 1, aged control rats liver and skin lipofuscin content obviously will be higher than green grass or young crops matched groups in age, aged control rats is taken after health product of the present invention, the old rats group low (P<0.01) that its liver and skin lipofuscin level all will not taken, points out health product of the present invention to have the effect that reduces aging rats liver and skin lipofuscin level.
The clinical therapeutic efficacy of the tea bag preparation of embodiment 2 health product of the present invention is observed
Take Semen Vaccariae 8g, Radix Angelicae Pubescentis 2g, pulverizes, and crosses 60 mesh sieves, and mix homogeneously, after disinfection by ultraviolet light, packs in tea bag, and sealing, obtains tea bag preparation.The method of making tea brews routinely, when tea-drinking use, every day potion.Model case:
1. XX recklessly, female, 55 years old, there was obvious dark brown senile plaque in face, takes this tea bag preparation 2 months, and senile plaque is obviously desalinated.
2. Lee XX, female, 62 years old, depression, face jaundice, has chloasma, and when tea bag preparation 4 months for tea-drinking, chloasma be can't see substantially, and it is very good that the mental status oneself is felt.
3. king XX, female, 45 years old, suffer from climacteric syndrome, mood is irritated, and insomnia, takes tea bag preparation of the present invention 1 month, and symptom disappears substantially.
4. Lee present inventor XX, man 74 years old, as tea-drinking the present invention, face is without senile plaque, energetic for a long time.
5. an XX, female, 35 years old, complexion jaundice, QI and blood is obstructed, takes tea bag preparation of the present invention 1 month, and successful is got better.
6. room XX, man, 48 years old, carcinoma of prostate, urinated uneasy, took tea bag preparation of the present invention, and 1 month takes effect, unobstructed micturition.
7. an XX, man 56 years old, nephritis, urinates uneasy, takes tea bag preparation of the present invention, and 10 days take effect.
Claims (7)
1. health product, is characterized in that, described health product are comprised of the crude drug of following weight proportion: Semen Vaccariae, 75～95 weight portions; Radix Angelicae Pubescentis, 5～25 weight portions.
2. health product as claimed in claim 1, is characterized in that, described health product are comprised of the crude drug of following weight proportion: Semen Vaccariae, 80 weight portions; Radix Angelicae Pubescentis, 20 weight portions.
3. health product, is characterized in that, described health product are made through extracting separated extract by the crude drug described in claim 1 or 2.
4. health product as claimed in claim 3, is characterized in that, the extract extraction separation method of described crude drug is: the crude drug of getting recipe quantity, be ground into coarse powder, mix homogeneously, decocts or soaks and extract 1～5 time with 3～10 times of water gagings, filter, get filtrate, concentrate and get final product.
5. health product, is characterized in that, described health product are comprised of with adjuvant health product and the food described in claim 1-4 any one.
6. health product as claimed in claim 5, is characterized in that, the dosage form of described health product is any one in powder, powder, tablet, granule, decoction, oral liquid, sweet mastic, honeydew, beverage or tea bag preparation.
7. health product as claimed in claim 6, is characterized in that, the preparation method of described powder or tea bag preparation is: take described crude drug, be ground into 60～80 order powderies, mix homogeneously packs in sterilising filtration tea bag or sterilizing bag after sterilization, and sealing is preserved.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310692618.4A CN103735600B (en) | 2013-12-17 | 2013-12-17 | A kind of health product |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310692618.4A CN103735600B (en) | 2013-12-17 | 2013-12-17 | A kind of health product |
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| Publication Number | Publication Date |
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| CN103735600A true CN103735600A (en) | 2014-04-23 |
| CN103735600B CN103735600B (en) | 2016-04-13 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106616978A (en) * | 2016-11-25 | 2017-05-10 | 河池市农业科学研究所 | Human body health-care product and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097132A (en) * | 1993-07-07 | 1995-01-11 | 曹斌 | Zhenlongyin health-care wine |
| CN102430099A (en) * | 2012-01-04 | 2012-05-02 | 揭静华 | Life-prolonging essence |
-
2013
- 2013-12-17 CN CN201310692618.4A patent/CN103735600B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097132A (en) * | 1993-07-07 | 1995-01-11 | 曹斌 | Zhenlongyin health-care wine |
| CN102430099A (en) * | 2012-01-04 | 2012-05-02 | 揭静华 | Life-prolonging essence |
Non-Patent Citations (3)
| Title |
|---|
| 李凤兰: "《实用中医中药与妇科临床》", 31 January 1999, article "王不留行", pages: 204 * |
| 武晓群等: "中医药延缓衰老机制的研究进展", 《中医研究》, vol. 20, no. 11, 30 November 2007 (2007-11-30), pages 59 - 61 * |
| 瞿幸: "黄褐斑的中医药治疗", 《中国民间疗法》, vol. 9, no. 2, 28 February 2001 (2001-02-28), pages 4 - 5 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106616978A (en) * | 2016-11-25 | 2017-05-10 | 河池市农业科学研究所 | Human body health-care product and preparation method thereof |
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