CN103732318B - 使用水力旋流器加工微球 - Google Patents
使用水力旋流器加工微球 Download PDFInfo
- Publication number
- CN103732318B CN103732318B CN201280009305.8A CN201280009305A CN103732318B CN 103732318 B CN103732318 B CN 103732318B CN 201280009305 A CN201280009305 A CN 201280009305A CN 103732318 B CN103732318 B CN 103732318B
- Authority
- CN
- China
- Prior art keywords
- suspension
- fluid
- microballoon
- fluid outlet
- outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04F—PUMPING OF FLUID BY DIRECT CONTACT OF ANOTHER FLUID OR BY USING INERTIA OF FLUID TO BE PUMPED; SIPHONS
- F04F5/00—Jet pumps, i.e. devices in which flow is induced by pressure drop caused by velocity of another fluid flow
- F04F5/44—Component parts, details, or accessories not provided for in, or of interest apart from, groups F04F5/02 - F04F5/42
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
- Cyclones (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/028,764 | 2011-02-16 | ||
| US13/028,764 US8708159B2 (en) | 2011-02-16 | 2011-02-16 | Manufacture of microspheres using a hydrocyclone |
| PCT/US2012/025378 WO2012112747A2 (en) | 2011-02-16 | 2012-02-16 | Manufacture of microspheres using a hydrocyclone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103732318A CN103732318A (zh) | 2014-04-16 |
| CN103732318B true CN103732318B (zh) | 2016-04-13 |
Family
ID=46636079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280009305.8A Active CN103732318B (zh) | 2011-02-16 | 2012-02-16 | 使用水力旋流器加工微球 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8708159B2 (enExample) |
| EP (1) | EP2675559B1 (enExample) |
| JP (2) | JP6180327B2 (enExample) |
| CN (1) | CN103732318B (enExample) |
| AU (1) | AU2012217620B2 (enExample) |
| BR (1) | BR112013020648B1 (enExample) |
| ES (1) | ES2807350T3 (enExample) |
| MX (1) | MX2013009056A (enExample) |
| WO (1) | WO2012112747A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10188119B2 (en) | 2001-07-16 | 2019-01-29 | Foret Plasma Labs, Llc | Method for treating a substance with wave energy from plasma and an electrical arc |
| US8764978B2 (en) | 2001-07-16 | 2014-07-01 | Foret Plasma Labs, Llc | System for treating a substance with wave energy from an electrical arc and a second source |
| CA2683165C (en) | 2006-04-05 | 2013-06-11 | Foret Plasma Labs, Llc | System, method and apparatus for treating liquids with wave energy from plasma |
| US9185787B2 (en) | 2007-10-16 | 2015-11-10 | Foret Plasma Labs, Llc | High temperature electrolysis glow discharge device |
| US9761413B2 (en) | 2007-10-16 | 2017-09-12 | Foret Plasma Labs, Llc | High temperature electrolysis glow discharge device |
| US9516736B2 (en) | 2007-10-16 | 2016-12-06 | Foret Plasma Labs, Llc | System, method and apparatus for recovering mining fluids from mining byproducts |
| US10267106B2 (en) | 2007-10-16 | 2019-04-23 | Foret Plasma Labs, Llc | System, method and apparatus for treating mining byproducts |
| US9051820B2 (en) | 2007-10-16 | 2015-06-09 | Foret Plasma Labs, Llc | System, method and apparatus for creating an electrical glow discharge |
| US9560731B2 (en) | 2007-10-16 | 2017-01-31 | Foret Plasma Labs, Llc | System, method and apparatus for an inductively coupled plasma Arc Whirl filter press |
| US11806686B2 (en) | 2007-10-16 | 2023-11-07 | Foret Plasma Labs, Llc | System, method and apparatus for creating an electrical glow discharge |
| US9230777B2 (en) | 2007-10-16 | 2016-01-05 | Foret Plasma Labs, Llc | Water/wastewater recycle and reuse with plasma, activated carbon and energy system |
| US8278810B2 (en) | 2007-10-16 | 2012-10-02 | Foret Plasma Labs, Llc | Solid oxide high temperature electrolysis glow discharge cell |
| MX2010008819A (es) | 2008-02-12 | 2010-11-05 | Foret Plasma Labs Llc | Metodo, sistema y aparato para combustion con escaso combustible con plasma de arco electrico. |
| US8904749B2 (en) | 2008-02-12 | 2014-12-09 | Foret Plasma Labs, Llc | Inductively coupled plasma arc device |
| US10244614B2 (en) | 2008-02-12 | 2019-03-26 | Foret Plasma Labs, Llc | System, method and apparatus for plasma arc welding ceramics and sapphire |
| US8708159B2 (en) * | 2011-02-16 | 2014-04-29 | Oakwood Laboratories, Llc | Manufacture of microspheres using a hydrocyclone |
| MX379490B (es) * | 2012-12-11 | 2025-03-10 | Foret Plasma Labs Llc | Sistema de reactor de vortice a contracorriente a alta temperatura, metodo y aparato. |
| EP2971488B1 (en) | 2013-03-12 | 2018-09-26 | Foret Plasma Labs, Llc | Apparatus and method for sintering proppants |
| WO2014144309A1 (en) * | 2013-03-15 | 2014-09-18 | Oakwood Laboratories | Sustained release microspheres and method of producing the same |
| EP3784705A4 (en) * | 2018-04-23 | 2022-03-02 | Graybug Vision, Inc. | IMPROVED CONTINUOUS PRODUCTION OF MICROPARTICLES |
| DE102018207441B4 (de) * | 2018-05-15 | 2022-08-18 | Bayerische Motoren Werke Aktiengesellschaft | Verfahren zum Analysieren der in einem Betriebsfluid einer Vorrichtung enthaltenen Partikel sowie Vorrichtung zum Durchführen des Verfahrens |
| JP7157263B2 (ja) * | 2019-07-01 | 2022-10-19 | オークウッド ラボラトリーズ,エル.エル.シー. | ミクロスフェア及びエマルションを製造するためのシステム及び方法 |
| CN112494456B (zh) * | 2020-12-16 | 2022-05-03 | 西南石油大学 | 一种乙基纤维素中空微囊 |
| EP4598504A2 (en) | 2022-10-05 | 2025-08-13 | Mireca Medicines GmbH | Microparticle and implant formulations for cgmp analog therapy |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040119179A1 (en) * | 2000-10-19 | 2004-06-24 | Michel Perrut | Method for making very fine particles consisting of a principle inserted in a host molecule |
| US20050155541A1 (en) * | 2002-05-02 | 2005-07-21 | Mccausland Linda J. | Preparation of small crystals |
| CN101502818A (zh) * | 2009-03-05 | 2009-08-12 | 煤炭科学研究总院唐山研究院 | 一种粗煤泥水力分级分选一体化装置及分级分选系统 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3869559A (en) * | 1970-04-13 | 1975-03-04 | Thomas P Clark | Process for separation and cleaning of edible vegetable products |
| FR2381896A1 (fr) * | 1977-02-24 | 1978-09-22 | Elf Aquitaine | Recuperation des fluides de forage |
| US4279743A (en) * | 1979-11-15 | 1981-07-21 | University Of Utah | Air-sparged hydrocyclone and method |
| US4810264A (en) * | 1984-02-23 | 1989-03-07 | Shell Oil Company | Process for cleaning and splitting particle-containing fluid with an adjustable cyclone separator |
| GB9221329D0 (en) * | 1992-10-10 | 1992-11-25 | Delta Biotechnology Ltd | Preparation of further diagnostic agents |
| US6051256A (en) * | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
| GB9513659D0 (en) * | 1995-07-05 | 1995-09-06 | Advanced Assured Homes 17 Plc | Improvements in or relating to ultrasonic processors |
| JP3969771B2 (ja) * | 1996-10-29 | 2007-09-05 | 英人 吉田 | 液体サイクロンおよび液体サイクロンを用いた分離方法 |
| US5945126A (en) | 1997-02-13 | 1999-08-31 | Oakwood Laboratories L.L.C. | Continuous microsphere process |
| US6270802B1 (en) | 1998-10-28 | 2001-08-07 | Oakwood Laboratories L.L.C. | Method and apparatus for formulating microspheres and microcapsules |
| US6705757B2 (en) | 1999-11-12 | 2004-03-16 | Alkermes Controlled Therapeutics, Inc. Ii | Method and apparatus for preparing microparticles using in-line solvent extraction |
| JP4287613B2 (ja) * | 2000-04-28 | 2009-07-01 | 田辺三菱製薬株式会社 | マイクロスフェアの製法 |
| IT1319693B1 (it) * | 2000-12-15 | 2003-10-23 | Eni Spa | Procedimento per la separazione di microsfere di vetro cave da fanghiche le contengono. |
| WO2004009200A2 (en) * | 2002-07-22 | 2004-01-29 | Mba Polymers, Inc. | Controlling media particle size in slurried dense media separations |
| JP2004053552A (ja) * | 2002-07-24 | 2004-02-19 | Toray Ind Inc | 液体流通装置内の液体流動状態の非破壊検査方法 |
| US6962006B2 (en) * | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
| US6892887B2 (en) * | 2003-02-10 | 2005-05-17 | Alpine Mud Products Corp | Polymer drilling bead recovery system and related methods |
| US6902593B2 (en) * | 2003-02-26 | 2005-06-07 | Kellogg Brown And Root, Inc. | Separation device to remove fine particles |
| JP2005227429A (ja) * | 2004-02-12 | 2005-08-25 | Fuji Photo Film Co Ltd | 写真廃液の処理装置及び方法 |
| US20090104274A1 (en) * | 2005-03-01 | 2009-04-23 | Ajay Khopade | Process of making microspheres |
| US7438142B2 (en) * | 2006-03-23 | 2008-10-21 | M-I Llc | Recovery system |
| US7520342B2 (en) * | 2006-03-23 | 2009-04-21 | M-I L.L.C. | Recovery system |
| EP1920765A1 (en) * | 2006-11-07 | 2008-05-14 | Medigene AG | Liposome preparation by single-pass process |
| US20130045393A1 (en) * | 2007-07-12 | 2013-02-21 | Dsm Ip Assets B.V. | Organic nano-particles and process for their preparation |
| CA2692892A1 (en) * | 2007-07-24 | 2009-01-29 | Michael Malakhov | Technology for the preparation of microparticles |
| KR100917185B1 (ko) | 2007-11-13 | 2009-09-15 | (주)아모레퍼시픽 | 고분자 입자제조장치, 고분자입자 제조방법 및 이 방법에의해 제조된 고분자 입자를 포함하는 조성물 |
| JP5757872B2 (ja) * | 2008-09-11 | 2015-08-05 | エボニック コーポレイションEvonik Corporation | 調整可能な抽出速度を有する溶媒抽出マイクロカプセル化 |
| KR100924236B1 (ko) | 2009-06-23 | 2009-10-29 | 충남대학교산학협력단 | 균일한 입도분포를 가지는 초미세입자의 신규한 제조방법 및 장치 |
| US8708159B2 (en) * | 2011-02-16 | 2014-04-29 | Oakwood Laboratories, Llc | Manufacture of microspheres using a hydrocyclone |
-
2011
- 2011-02-16 US US13/028,764 patent/US8708159B2/en active Active
-
2012
- 2012-02-16 ES ES12747099T patent/ES2807350T3/es active Active
- 2012-02-16 AU AU2012217620A patent/AU2012217620B2/en active Active
- 2012-02-16 BR BR112013020648A patent/BR112013020648B1/pt active IP Right Grant
- 2012-02-16 EP EP12747099.5A patent/EP2675559B1/en active Active
- 2012-02-16 JP JP2013554593A patent/JP6180327B2/ja active Active
- 2012-02-16 CN CN201280009305.8A patent/CN103732318B/zh active Active
- 2012-02-16 WO PCT/US2012/025378 patent/WO2012112747A2/en not_active Ceased
- 2012-02-16 MX MX2013009056A patent/MX2013009056A/es active IP Right Grant
-
2017
- 2017-03-06 JP JP2017041674A patent/JP6359138B2/ja active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040119179A1 (en) * | 2000-10-19 | 2004-06-24 | Michel Perrut | Method for making very fine particles consisting of a principle inserted in a host molecule |
| US20050155541A1 (en) * | 2002-05-02 | 2005-07-21 | Mccausland Linda J. | Preparation of small crystals |
| CN101502818A (zh) * | 2009-03-05 | 2009-08-12 | 煤炭科学研究总院唐山研究院 | 一种粗煤泥水力分级分选一体化装置及分级分选系统 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2675559B1 (en) | 2020-06-10 |
| CN103732318A (zh) | 2014-04-16 |
| JP6180327B2 (ja) | 2017-08-16 |
| EP2675559A4 (en) | 2018-01-24 |
| ES2807350T3 (es) | 2021-02-22 |
| WO2012112747A2 (en) | 2012-08-23 |
| BR112013020648A2 (pt) | 2016-10-18 |
| BR112013020648B1 (pt) | 2019-09-03 |
| JP2017148800A (ja) | 2017-08-31 |
| JP6359138B2 (ja) | 2018-07-18 |
| WO2012112747A3 (en) | 2012-11-15 |
| US20120205293A1 (en) | 2012-08-16 |
| AU2012217620A1 (en) | 2013-08-29 |
| AU2012217620B2 (en) | 2016-11-17 |
| US8708159B2 (en) | 2014-04-29 |
| JP2014511265A (ja) | 2014-05-15 |
| MX2013009056A (es) | 2013-12-02 |
| EP2675559A2 (en) | 2013-12-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |