CN103721123B - A kind of Chinese medicine composition for the treatment of chronic prostatitis - Google Patents
A kind of Chinese medicine composition for the treatment of chronic prostatitis Download PDFInfo
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Abstract
Description
技术领域technical field
本发明涉及中药制剂领域，特别涉及一种治疗慢性前列腺炎的中药组合物及其制备方法。The invention relates to the field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method thereof.
背景技术Background technique
慢性前列腺炎是男性生殖系统的常见病，在泌尿外科男性患者中50岁以下组占首位，51岁以上组居第2位。其发病率高达6%。人群中有前列腺炎者占8%。慢性前列腺炎以排尿刺激症状和膀胱生殖区疼痛为主要表现的临床综合征。主要临床表现：疼痛：常位于会阴部及盆部，也常出现于阴茎、睾丸、腹股沟、耻骨上区、下腰部以及背部等处；尿路刺激症状：尿频、尿急、尿痛、夜尿次数增多以及尿道滴白等；排尿梗阻症状：排尿踌躇、尿线变细、排尿费力、尿不尽感等；性功能症状：早泄、射精疼痛、血精等。精神神经症状：失眠、焦虑、紧张等。西药偏重抗生素药物的治疗，治疗效果不好，发明人经过多年的临床实践发现，中药对于慢性前列腺炎的治疗效果很好。Chronic prostatitis is a common disease of the male reproductive system. Among male urological patients, the group under 50 years old occupies the first place, and the group over 51 years old ranks second. Its incidence rate is as high as 6%. Prostatitis accounted for 8% of the population. Chronic prostatitis is a clinical syndrome characterized by urinary irritation and pain in the genital area of the bladder. Main clinical manifestations: Pain: often located in the perineum and pelvis, and often in the penis, testis, groin, suprapubic area, lower waist, and back; urinary tract irritation symptoms: frequent urination, urgency, dysuria, nocturia Increased frequency and urethral dripping, etc.; urinary obstruction symptoms: urination hesitancy, urinary stream thinning, urination effort, feeling of incomplete urination, etc.; sexual function symptoms: premature ejaculation, ejaculation pain, blood semen, etc. Psychiatric symptoms: insomnia, anxiety, nervousness, etc. Western medicine lays particular stress on the treatment of antibiotic medicine, and curative effect is not good, and inventor finds through years of clinical practice, and Chinese medicine is very good for the therapeutic effect of chronic prostatitis.
发明内容Contents of the invention
针对现有技术中存在的缺陷，本发明的目的在于提供一种治疗慢性前列腺炎的中药组合物及其制备方法。Aiming at the defects in the prior art, the object of the present invention is to provide a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method thereof.
本发明的技术方案如下：Technical scheme of the present invention is as follows:
一种治疗慢性前列腺炎的中药组合物，由以下组分按照重量分数组成：A traditional Chinese medicine composition for treating chronic prostatitis, which consists of the following components according to weight fraction:
苍术40-50份，茯苓40-50份，薏苡仁40-50份，白术40-50份，刺五加40-50份，琥珀20-30份，血竭20-30份，丹皮20-30份，益母草20-30份，降香20-30份，白芥子5-15份，全蝎5-15份，蜈蚣5-15份。40-50 parts of Cangzhu, 40-50 parts of Poria cocos, 40-50 parts of coix seed, 40-50 parts of Atractylodes macrocephala, 40-50 parts of Acanthopanax, 20-30 parts of amber, 20-30 parts of dried blood, 20- 30 parts, motherwort 20-30 parts, jiangxiang 20-30 parts, white mustard seed 5-15 parts, scorpion 5-15 parts, centipede 5-15 parts.
一种治疗慢性前列腺炎的中药组合物，由以下组分按照重量分数组成：A traditional Chinese medicine composition for treating chronic prostatitis, which consists of the following components according to weight fraction:
苍术45份，茯苓45份，薏苡仁45份，白术45份，刺五加45份，琥珀25份，血竭25份，丹皮25份，益母草25份，降香25份，白芥子10份，全蝎10份，蜈蚣10份。45 parts of Cangzhu, 45 parts of Poria cocos, 45 parts of Coix seed, 45 parts of Atractylodes macrocephala, 45 parts of Acanthopanax, 25 parts of amber, 25 parts of blood, 25 parts of paeonol, 25 parts of motherwort, 25 parts of Jiangxiang, 10 parts of white mustard seed , 10 parts of scorpion, 10 parts of centipede.
在上述方案的基础上，一种治疗慢性前列腺炎的中药组合物，具体的制备方法如下：On the basis of the above-mentioned scheme, a kind of Chinese medicinal composition for the treatment of chronic prostatitis, the specific preparation method is as follows:
1）按量称取上述组合物，将除琥珀外的其他组分粉碎至100目，将琥珀粉碎至500目。1) Weigh the above composition according to the amount, crush the other components except amber to 100 mesh, and crush the amber to 500 mesh.
2）将除琥珀外的各组分充分混合后加入到900份水中，浸泡24小时后煮沸30分钟；2) Fully mix all components except amber and add to 900 parts of water, soak for 24 hours and boil for 30 minutes;
3）过滤后弃掉滤渣；3) Discard the filter residue after filtering;
4）将滤液浓缩至300份；4) Concentrate the filtrate to 300 parts;
5）将琥珀加入到滤液中。5) Add amber to the filtrate.
本发明所述的组方中：苍术燥湿健脾，茯苓利水渗湿、健脾，薏苡仁利水渗湿、健脾，白术补气健脾、燥湿利水，刺五加益气健脾，五药合用共奏健脾、利水之功效，为君药；琥珀活血散瘀，血竭活血散瘀，丹皮活血散瘀，益母草活血祛瘀，降香活血散瘀，五药共为臣药；白芥子通络止痛，全蝎通络止痛，蜈蚣通络止痛，三药共为佐药；十三药合用，共奏健脾、利水、活血散瘀、通络止痛之功效。In the prescription of the present invention: Atractylodes rhizome for removing dampness and invigorating the spleen, Poria cocos for diuresis and expelling dampness and invigorating the spleen, coix seed for dispelling water and expelling dampness and invigorating the spleen, Atractylodes macrocephala for invigorating qi and invigorating the spleen, eliminating dampness for diuresis, Acanthopanax acanthopanax for nourishing qi and invigorating the spleen, The combination of five medicines has the effects of invigorating the spleen and diuresis, and it is the king medicine; Amber promotes blood circulation and dispels blood stasis, Xuejie promotes blood circulation and dispels blood stasis, paeonol promotes blood circulation and dispels blood stasis, motherwort promotes blood circulation and dispels blood stasis, Jiangxiang promotes blood circulation and dispels blood stasis, the five medicines are ministerial medicines White mustard seed dredging collaterals to relieve pain, scorpion dredging collaterals to relieve pain, centipede dredging collaterals to relieve pain, the three medicines are adjuvant drugs altogether; 13 medicines are used in combination to play the effects of invigorating the spleen, diuresis, promoting blood circulation and dissipating blood stasis, dredging collaterals and relieving pain.
本发明所述的中药组合物，为纯中药制剂，毒副作用小，成本低，标本兼治，超微粉碎，药效更加显著。The traditional Chinese medicine composition of the present invention is a pure traditional Chinese medicine preparation, has less toxic and side effects, low cost, treats both symptoms and root causes, is superfinely pulverized, and has more remarkable drug effects.
具体实施方式detailed description
实施例1Example 1
一种治疗慢性前列腺炎的中药组合物，由以下组分按照重量分数组成（每份1g）：A traditional Chinese medicine composition for treating chronic prostatitis, which consists of the following components according to the weight fraction (1g per part):
苍术40份，茯苓40份，薏苡仁40份，白术40份，刺五加40份，琥珀20份，血竭20份，丹皮20份，益母草20份，降香20份，白芥子5份，全蝎5份，蜈蚣5份。40 parts of Cangzhu, 40 parts of Poria cocos, 40 parts of coix seed, 40 parts of Atractylodes macrocephala, 40 parts of Acanthopanax, 20 parts of amber, 20 parts of blood, 20 parts of paeonol, 20 parts of motherwort, 20 parts of Jiangxiang, 5 parts of white mustard seed , 5 parts of scorpion, 5 parts of centipede.
具体的制备方法如下：1）按量称取上述组合物，将除琥珀外的其他组分粉碎至100目，将琥珀粉碎至500目；2）将除琥珀外的各组分充分混合后加入到900份水中，浸泡24小时后煮沸30分钟；3）过滤后弃掉滤渣；4）将滤液浓缩至300份；5）将琥珀加入到滤液中。The specific preparation method is as follows: 1) Weigh the above composition according to the amount, crush the other components except amber to 100 mesh, and crush the amber to 500 mesh; 2) Mix the components except amber thoroughly and add To 900 parts of water, soak for 24 hours and then boil for 30 minutes; 3) Discard the filter residue after filtering; 4) Concentrate the filtrate to 300 parts; 5) Add amber to the filtrate.
实施例2Example 2
一种治疗慢性前列腺炎的中药组合物，由以下组分按照重量分数组成（每份1g）：A traditional Chinese medicine composition for treating chronic prostatitis, which consists of the following components according to the weight fraction (1g per part):
苍术45份，茯苓45份，薏苡仁45份，白术45份，刺五加45份，琥珀25份，血竭25份，丹皮25份，益母草25份，降香25份，白芥子10份，全蝎10份，蜈蚣10份。45 parts of Cangzhu, 45 parts of Poria cocos, 45 parts of Coix seed, 45 parts of Atractylodes macrocephala, 45 parts of Acanthopanax, 25 parts of amber, 25 parts of blood, 25 parts of paeonol, 25 parts of motherwort, 25 parts of Jiangxiang, 10 parts of white mustard seed , 10 parts of scorpion, 10 parts of centipede.
具体的制备方法如下：1）按量称取上述组合物，将除琥珀外的其他组分粉碎至100目，将琥珀粉碎至500目。2）将除琥珀外的各组分充分混合后加入到900份水中，浸泡24小时后煮沸30分钟；3）过滤后弃掉滤渣；4）将滤液浓缩至300份；5）将琥珀加入到滤液中。The specific preparation method is as follows: 1) Weigh the above composition according to the amount, grind the other components except amber to 100 mesh, and crush the amber to 500 mesh. 2) Fully mix all components except amber and add to 900 parts of water, soak for 24 hours and boil for 30 minutes; 3) Discard the filter residue after filtering; 4) Concentrate the filtrate to 300 parts; 5) Add amber to in the filtrate.
实施例3Example 3
一种治疗慢性前列腺炎的中药组合物，由以下组分按照重量分数组成（每份1g）：A traditional Chinese medicine composition for treating chronic prostatitis, which consists of the following components according to the weight fraction (1g per part):
苍术50份，茯苓50份，薏苡仁50份，白术50份，刺五加50份，琥珀30份，血竭30份，丹皮30份，益母草30份，降香30份，白芥子15份，全蝎15份，蜈蚣15份。50 parts of Cangzhu, 50 parts of Poria cocos, 50 parts of Coix seed, 50 parts of Atractylodes macrocephala, 50 parts of Acanthopanax, 30 parts of amber, 30 parts of dried blood, 30 parts of paeonol, 30 parts of motherwort, 30 parts of Jiangxiang, 15 parts of white mustard seed , 15 parts of scorpion, 15 parts of centipede.
具体的制备方法如下：1）按量称取上述组合物，将除琥珀外的其他组分粉碎至100目，将琥珀粉碎至500目。2）将除琥珀外的各组分充分混合后加入到900份水中，浸泡24小时后煮沸30分钟；3）过滤后弃掉滤渣；4）将滤液浓缩至300份；5）将琥珀加入到滤液中。The specific preparation method is as follows: 1) Weigh the above composition according to the amount, grind the other components except amber to 100 mesh, and crush the amber to 500 mesh. 2) Fully mix all components except amber and add to 900 parts of water, soak for 24 hours and boil for 30 minutes; 3) Discard the filter residue after filtering; 4) Concentrate the filtrate to 300 parts; 5) Add amber to in the filtrate.
本发明中药组合物于2008年至2010年临床观察慢性前列腺炎58例患者，临床报告如下：The Chinese medicine composition of the present invention clinically observed 58 patients with chronic prostatitis from 2008 to 2010, and the clinical reports are as follows:
1、一般资料1. General Information
58例患者中，年龄最小35岁，最大72岁，病程多在6个月到6年，平均年龄43.2岁。Among the 58 patients, the youngest was 35 years old and the oldest was 72 years old. The course of disease was mostly 6 months to 6 years, and the average age was 43.2 years old.
2、诊断标准2. Diagnostic criteria
依据中华人民共和国中医药执业标准《中医外科病证诊断疗效标准》中慢性前列腺炎的诊断标准确诊：(1)小腹、会阴、睾丸部有胀痛不适感，轻度尿频，排尿或大便时尿道可有白色分泌物溢出；(2)可伴有神疲乏力、头晕、腰酸痛、性欲减退、遗精、早泄、阳痿、不育等症；(3)以男性中青年为多见，常为渐渐形成，时轻时重多反复发作；(4)直肠指检：精室增大或者缩小，有压痛；(5)前列腺液镜检：高倍视野白细胞10个以上或成堆，卵磷脂小体显著减少或消失；(6)舌质紫或有瘀斑点，苔白或黄，脉沉涩。凡具备(1)和(2)～(6)中任何3项者即可确诊。According to the diagnostic criteria of chronic prostatitis in the Chinese Medicine Practice Standards of the People's Republic of China "Standards for the Diagnosis and Curative Effect of Surgical Diseases and Syndrome of Traditional Chinese Medicine": (1) Pain and discomfort in the lower abdomen, perineum, and testicles, mild frequent urination, urethra when urinating or defecating White discharge may overflow; (2) may be accompanied by fatigue, dizziness, back pain, loss of libido, spermatorrhea, premature ejaculation, impotence, infertility and other symptoms; (3) more common in young and middle-aged men, often gradually (4) Digital rectal examination: enlarged or reduced seminal chambers, with tenderness; (5) Microscopic examination of prostatic fluid: more than 10 white blood cells or piles in high power field, and lecithin corpuscles are prominent Reduce or disappear; (6) purple tongue or ecchymosis, white or yellow fur, deep pulse. Anyone who has any 3 items in (1) and (2)-(6) can be diagnosed.
3、治疗方法3. Treatment method
3.1本发明实施例2所制备的中药组合物。3.1 Chinese medicine composition prepared by the embodiment of the present invention 2.
3.2服用方法：每次150ml，每日2次，每日1剂，10天为1疗程，连续服用6个疗程。3.2 Dosing method: 150ml each time, 2 times a day, 1 dose per day, 10 days as a course of treatment, 6 consecutive courses of treatment.
4、治疗结果：4. Treatment results:
4.1依据中华人民共和国中医药执业标准《中医外科病证诊断疗效标准》制定。4.1 Formulated according to the People's Republic of China Traditional Chinese Medicine Practice Standards "Diagnosis and Curative Effect Standards for Surgical Diseases and Syndromes of Traditional Chinese Medicine".
痊愈：体征均消失，前列腺液常规检查WRC＜5个/HP，卵磷脂小体+--+++；Recovery: signs disappeared, routine examination of prostatic fluid WRC<5/HP, lecithin bodies +--+++;
好转：临床症状明显改善或有50％症状消失，WRC＜10个/HP，卵磷脂小体+--++；Improvement: clinical symptoms improved significantly or 50% of symptoms disappeared, WRC<10/HP, lecithin bodies +--++;
无效：症状体征检查均无改变。Invalid: No changes in symptoms and signs.
4.2结果：58例患者中，痊愈42例(72.4％)，有效14例(24.1％)，无效2例(3.5％)，总有效率为96.5％。4.2 Results: Among the 58 patients, 42 were cured (72.4%), 14 were effective (24.1%), and 2 were ineffective (3.5%). The total effective rate was 96.5%.
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|---|---|---|---|
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1085080A (en) * | 1993-01-17 | 1994-04-13 | 莫雨茂 | A kind of medicated wine |
| CN101537154A (en) * | 2008-09-12 | 2009-09-23 | 罗春青 | Manufacturing method of medicament for treating ten kinds of diseases |
| CN101732660A (en) * | 2009-12-25 | 2010-06-16 | 卢速江 | Chinese medicinal preparation for treating prostate disease and preparation method thereof |
| CN101829299A (en) * | 2010-01-18 | 2010-09-15 | 郑延明 | External use paste for preventing and treating prostatosis and preparation method thereof |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1085080A (en) * | 1993-01-17 | 1994-04-13 | 莫雨茂 | A kind of medicated wine |
| CN101537154A (en) * | 2008-09-12 | 2009-09-23 | 罗春青 | Manufacturing method of medicament for treating ten kinds of diseases |
| CN101732660A (en) * | 2009-12-25 | 2010-06-16 | 卢速江 | Chinese medicinal preparation for treating prostate disease and preparation method thereof |
| CN101829299A (en) * | 2010-01-18 | 2010-09-15 | 郑延明 | External use paste for preventing and treating prostatosis and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 中医药治疗慢性前列腺炎的临床研究进展;卫培峰等;《现代中医药》;20011231(第04期);44-46 * |
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