CN103705632B - The application of BUPIXIAO PIAN in preparation treatment penile induration disease drug - Google Patents
The application of BUPIXIAO PIAN in preparation treatment penile induration disease drug Download PDFInfo
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- CN103705632B CN103705632B CN201310735112.7A CN201310735112A CN103705632B CN 103705632 B CN103705632 B CN 103705632B CN 201310735112 A CN201310735112 A CN 201310735112A CN 103705632 B CN103705632 B CN 103705632B
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Abstract
The invention belongs to medical art, relate to a kind of novelty teabag of Chinese patent medicine, be specifically related to the application of BUPIXIAO PIAN in preparation treatment penile induration disease drug.The prescription of BUPIXIAO PIAN and preparation method are: Cornu Cervi, Herba Taraxaci, Thallus Laminariae (Thallus Eckloniae), Radix Trichosanthis, Caulis Spatholobi, Radix Notoginseng, Radix Paeoniae Rubra, Sargassum, Radix Rhapontici, the Radix Aucklandiae, Radix Scrophulariae, Cortex Moutan, Spica Prunellae, Fructus Forsythiae, Flos Carthami, upper ten five tastes, Radix Scrophulariae, Radix Notoginseng, Cornu Cervi are ground into fine powder respectively; 12 tastes such as all the other Herba Taraxacis decoct with water secondary, 3 hours first times, second time 2 hours, and collecting decoction filters, and be concentrated into appropriate, with above-mentioned fine powder and appropriate auxiliary materials and mixing, make granule, dry, tabletting, sugar coating, to obtain final product.BUPIXIAO PIAN has hard masses softening and resolving, effect of pain, heat-clearing and toxic substances removing of disappearing of invigorating blood circulation, and now finds that it orally can treat induration of penis.
Description
Technical field
The invention belongs to medical art, relate to a kind of novelty teabag of Chinese patent medicine, be specifically related to the application of BUPIXIAO PIAN in preparation treatment penile induration disease drug.
Background technology
Induration of penis is also known as fibrous cavernositis of penis, it is the fibrosis lesion betiding albuginea of cavernous body of penis, first since being found by Italian doctor Fallopius from 1561, its sickness rate is always in rising trend, especially in recent years along with vasoactive agent injection for curing in cavernous body of penis and diagnosis Erectile Dysfunction day by day universal, induration of penis is clinical of common occurrence in andrology, because the cause of disease of primary disease is not yet completely clear, therefore people cannot find single and effective method treat and prevent induration of penis always for many years.
It is relevant that current most scholar thinks that the generation of induration of penis and penis damage the factor such as local inflammation, interior point of disorder, vitamin E deficiency and autoimmune repeatedly, take to observe wait, oral rope E or the operative treatment of supporting one's family to this type of patient's modern medicine more, but from clinical observation on the therapeutic effect, vitamin E curative effect is general, and some scholars thinks that its curative effect is equal to placebo.Clinical conventional Therapeutic Method also comprises Drug therapy as oral colchicine, local injection treatment is as local injection interferon, verapamil etc., though can temporarily suppress fibrocellular hypertrophy, effective percentage is not high, only reaches 50% ~ 60%, easily recur after drug withdrawal, and untoward reaction is comparatively large, surgical orthopaedic treatment is only applicable to the patient of penis severe bends in late period, and operative treatment induration of penis has again traumatic, and it is multiple to harden, postoperatively very easily to regenerate.In a word, induration of penis also lacks gratifying treatment means at present.Therefore a kind of Chinese medicine for the treatment of induration of penis is badly in need of.
There are good nurse's Pharmaceutical (group) Co., Ltd in Liaoning and Shenyang Hongyao Pharmaceutical Co., Ltd. 2 production in the current China of BUPIXIAO PIAN.There is hard masses softening and resolving, effect of pain, heat-clearing and toxic substances removing of disappearing of invigorating blood circulation, be mainly used in the nodules of the breast caused by combination of phlegm and heat, acute mastitis disease see breast tuberosity, number not etc. size and form does not differ, quality breast red heat pain in soft or puerperal, cyclomastopathy, mastitis are shown in above-mentioned disease person in early days.Also there is no the bibliographical information of its treatment treatment induration of penis at present.
Summary of the invention
Goal of the invention: the object of the present invention is to provide the application of BUPIXIAO PIAN in preparation treatment penile induration disease drug.
Technical scheme: the application of BUPIXIAO PIAN in preparation treatment penile induration disease drug.
The prescription of BUPIXIAO PIAN and preparation method are: Cornu Cervi, Herba Taraxaci, Thallus Laminariae (Thallus Eckloniae), Radix Trichosanthis, Caulis Spatholobi, Radix Notoginseng, Radix Paeoniae Rubra, Sargassum, Radix Rhapontici, the Radix Aucklandiae, Radix Scrophulariae, Cortex Moutan, Spica Prunellae, Fructus Forsythiae, Flos Carthami, upper ten five tastes, Radix Scrophulariae, Radix Notoginseng, Cornu Cervi are ground into fine powder respectively; 12 tastes such as all the other Herba Taraxacis decoct with water secondary, 3 hours first times, second time 2 hours, and collecting decoction filters, and be concentrated into appropriate, with above-mentioned fine powder and appropriate auxiliary materials and mixing, make granule, dry, tabletting, sugar coating, to obtain final product.
Beneficial effect: BUPIXIAO PIAN treatment induration of penis, respond well.Clinical test results shows, and BUPIXIAO PIAN is used for treating induration of penis, and 6 course cure rates are up to 59.4%, and colchicines tablets matched group cure rate only has 10.0%, and both have significant difference (p < 0.01); 6 the course for the treatment of total effective rate up to 93.6%, and colchicines tablets matched group effective percentage only has 56.7%, and both have significant difference (p < 0.01).
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Detailed description of the invention
The clinical data of BUPIXIAO PIAN treatment induration of penis
Clinical medicine:
Colchicines tablets, Tonghua Limin Pharmaceutical Industry Co., Ltd., specification: 0.5mg/ sheet, lot number is 20120715.
BUPIXIAO PIAN, Shenyang Hongyao Pharmaceutical Co., Ltd., specification 0.67g/ sheet, lot number is 2010.916.
1.1 physical data patient ages 26 ~ 48 years old, average 36.8 years old.January ~ 5 year are asked during morbidity.Average 13 months.Treatment group 32 routine single-shot scleroma person l8 example, multiple scleroma (2 ~ 4 pieces) person 14 example.No conscious sympton person 16 example, with erection pain person 10 example, penis lateral bending person 4 example after erecing, part has sexual impotence person 2 example; This organizes none routine dysuria.24 examples are had to show through ultrasound diagnosis.Medium or slightly strong echo nodules is seen in albuginea penis district, sharpness of border.Wherein 2 examples have calcification.Matched group 30 routine single-shot scleroma person l7 example, multiple scleroma (2 ~ 4 pieces) person 13 example.No conscious sympton person 15 example, with erection pain person 10 example, penis lateral bending person 5 example after erecing, part has sexual impotence person 1 example; This organizes none routine dysuria.19 examples are had to show through ultrasound diagnosis.Medium or slightly strong echo nodules is seen in albuginea penis district, sharpness of border.Wherein 1 example has calcification.
1.2 Therapeutic Method
The oral colchicines tablets of matched group, a 1mg, 3 times on the one.It within 7 days, is 1 course for the treatment of.Take 2 courses for the treatment of to have a rest one week.Observed result after 6 courses for the treatment of.
The oral BUPIXIAO PIAN for the treatment of group, one time 3,3 times on the one.It within 7 days, is 1 course for the treatment of.Take 2 courses for the treatment of to have a rest one week.Observed result after 6 courses for the treatment of.
3 therapeutic outcomes
After all treatments of 3.1 criterion of therapeutical effect, penile induration disappears, and the clinical symptoms such as phallocampsis, pain eliminator is clinical cure; After treatment, penile induration reduces, and the clinical symptoms such as phallocampsis, pain improver be effectively clinical, and after treatment, penile induration is unchanged or increase further, and clinical symptoms is invalid without improving or adding severe one.
3.2 therapeutic outcome two groups efficacy results see the following form.
A table 1 liang group curative effect of medication compares
Compared with colchicines tablets matched group, BUPIXIAO PIAN is used for treating induration of penis, and 6 course cure rates are up to 59.4%, and matched group cure rate only has 10.0%, and both have significant difference (p < 0.01); 6 the course for the treatment of total effective rate up to 93.6%, and matched group effective percentage only has 56.7%, and both have significant difference (p < 0.01).
Claims (1)
1. the application of BUPIXIAO PIAN in preparation treatment penile induration disease drug, it is characterized in that, the prescription of described BUPIXIAO PIAN and preparation method are: Cornu Cervi, Herba Taraxaci, Thallus Laminariae (Thallus Eckloniae), Radix Trichosanthis, Caulis Spatholobi, Radix Notoginseng, Radix Paeoniae Rubra, Sargassum, Radix Rhapontici, the Radix Aucklandiae, Radix Scrophulariae, Cortex Moutan, Spica Prunellae, Fructus Forsythiae, Flos Carthami, upper ten five tastes, Radix Scrophulariae, Radix Notoginseng, Cornu Cervi are ground into fine powder respectively; 12 tastes such as all the other Herba Taraxacis decoct with water secondary, 3 hours first times, second time 2 hours, and collecting decoction filters, and be concentrated into appropriate, with above-mentioned fine powder and appropriate auxiliary materials and mixing, make granule, dry, tabletting, sugar coating, to obtain final product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310735112.7A CN103705632B (en) | 2013-12-27 | 2013-12-27 | The application of BUPIXIAO PIAN in preparation treatment penile induration disease drug |
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| CN201310735112.7A CN103705632B (en) | 2013-12-27 | 2013-12-27 | The application of BUPIXIAO PIAN in preparation treatment penile induration disease drug |
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| CN103705632B true CN103705632B (en) | 2015-09-16 |
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| CN104056208A (en) * | 2014-07-15 | 2014-09-24 | 张鑫琦 | Medicament for treating penis induration and preparation method thereof |
| CN104998043A (en) * | 2015-08-20 | 2015-10-28 | 曲效橹 | Traditional Chinese medicine composition for peyronie's disease |
| CN105056188A (en) * | 2015-08-20 | 2015-11-18 | 刘林 | Traditional Chinese medicine for Peyronie's disease |
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| CN1113757A (en) * | 1994-06-24 | 1995-12-27 | 王儒新 | Sexual function improving agent and its preparing method |
| CN102038799B (en) * | 2010-12-07 | 2012-07-04 | 哈尔滨泰华药业股份有限公司 | Application of breast lump-elimination preparation in preparing medicines for treating dysmenorrhea |
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