CN105056188A - Traditional Chinese medicine for Peyronie's disease - Google Patents

Traditional Chinese medicine for Peyronie's disease Download PDF

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Publication number
CN105056188A
CN105056188A CN201510511758.6A CN201510511758A CN105056188A CN 105056188 A CN105056188 A CN 105056188A CN 201510511758 A CN201510511758 A CN 201510511758A CN 105056188 A CN105056188 A CN 105056188A
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parts
radix
chinese medicine
traditional chinese
induration
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刘林
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Abstract

The invention belongs to the technical field of medicine, and particularly relates to traditional Chinese medicine for Peyronie's disease and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine consists of the following traditional Chinese medicine composition raw materials: 3-7 parts of fructus evodiae, 4-8 parts of cassia twig, 4-8 parts of ligusticum wallichii, 6-14 parts of Chinese angelica, 11-19 parts of radix paeoniae alba, 5-13 parts of cortex moutan, 3-7 parts of ginger, 6-14 parts of pinellia ternata, 14-22 parts of radix ophiopogonis, 11-19 parts of codonopsis pilosula, 6-14 parts of gelatina nigra, 5-13 parts of roasted radix glycyrrhizae, 15-25 parts of cowherb seed and 25-35 parts of prunella vulgaris. The traditional Chinese medicine has the efficacies of tonifying qi, activating blood, dispersing phlegm and eliminating abdominal mass, and is used for Peyronie's disease. When 80 patients with Peyronie's disease are treated, and the effective rate reaches up to 96.25%.

Description

A kind of Chinese medicine for induration of penis
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine for induration of penis.
Background technology
Induration of penis is fibrous cavernositis of penis again, be more common in middle age, be because the fibrosis lesion between cavernous body of penis and tunica albuginea, cause normal elastic force connective tissue and replaced by glass degeneration or fibrous scar, then occur single or multiple speckle in penis dorsal part or both sides.Because speckle follows the string, so penis is bending in time erecing, although primary disease diseased region limitation, because speckle can cause erection pain, phallocampsis deformity and pathological changes far-end to erect not hard, can sexual life be affected time serious, therefore should draw attention.Its sickness rate is always in rising trend, especially in recent years along with vasoactive agent injection for curing in cavernous body of penis and diagnosis Erectile Dysfunction day by day universal. induration of penis is clinical of common occurrence in andrology, because the cause of disease of primary disease is not yet completely clear, therefore people cannot find single and effective method treat and prevent induration of penis always for many years.It is relevant that current most scholar thinks that the generation of induration of penis damages repeatedly with penis, local inflammation, endocrine regulation, vitamin E deficiency and autoimmune raise factor, take to observe wait, oral rope E or the operative treatment of supporting one's family to this Lou patient modern medicine more, but from clinical observation on the therapeutic effect, vitamin E curative effect is general, some scholars thinks that its curative effect is equal to placebo, and operative treatment induration of penis has traumatic. and it is multiple to harden, and postoperatively very easily regenerates.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of Chinese medicine for induration of penis and application thereof.
The present invention is realized by following technical scheme:
For a Chinese medicine for induration of penis, be made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 3-7 part, Ramulus Cinnamomi 4-8 part, Rhizoma Chuanxiong 4-8 part, Radix Angelicae Sinensis 6-14 part, Radix Paeoniae Alba 11-19 part, Cortex Moutan 5-13 part, Rhizoma Zingiberis Recens 3-7 part, Rhizoma Pinelliae 6-14 part, Radix Ophiopogonis 14-22 part, Radix Codonopsis 11-19 part, Colla Corii Asini 6-14 part, Radix Glycyrrhizae Preparata 5-13 part, Semen Vaccariae 15-25 part, Spica Prunellae 25-35 part.
Preferably, the above-mentioned Chinese medicine for induration of penis, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 4-6 part, Ramulus Cinnamomi 5-7 part, Rhizoma Chuanxiong 5-7 part, Radix Angelicae Sinensis 8-12 part, Radix Paeoniae Alba 13-17 part, Cortex Moutan 7-11 part, Rhizoma Zingiberis Recens 4-6 part, Rhizoma Pinelliae 8-12 part, Radix Ophiopogonis 16-20 part, Radix Codonopsis 13-17 part, Colla Corii Asini 8-12 part, Radix Glycyrrhizae Preparata 7-11 part, Semen Vaccariae 18-22 part, Spica Prunellae 28-32 part.
Preferred, the above-mentioned Chinese medicine for induration of penis, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 5 parts, Ramulus Cinnamomi 6 parts, Rhizoma Chuanxiong 6 parts, Radix Angelicae Sinensis 10 parts, the Radix Paeoniae Alba 15 parts, Cortex Moutan 7-11 part, 5 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 10 parts, Radix Ophiopogonis 18 parts, Radix Codonopsis 15 parts, 10 parts, Colla Corii Asini, Radix Glycyrrhizae Preparata 9 parts, Semen Vaccariae 20 parts, Spica Prunellae 30 parts.
Or preferred, the above-mentioned Chinese medicine for induration of penis, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 4 parts, Ramulus Cinnamomi 5 parts, Rhizoma Chuanxiong 5 parts, Radix Angelicae Sinensis 8 parts, the Radix Paeoniae Alba 13 parts, Cortex Moutan 7 parts, 4 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 8 parts, Radix Ophiopogonis 16 parts, Radix Codonopsis 13 parts, 8 parts, Colla Corii Asini, Radix Glycyrrhizae Preparata 7 parts, Semen Vaccariae 18 parts, Spica Prunellae 28 parts.
Or preferred, the above-mentioned Chinese medicine for induration of penis, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 6 parts, Ramulus Cinnamomi 7 parts, Rhizoma Chuanxiong 7 parts, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 17 parts, Cortex Moutan 11 parts, 6 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 12 parts, Radix Ophiopogonis 20 parts, Radix Codonopsis 17 parts, 12 parts, Colla Corii Asini, Radix Glycyrrhizae Preparata 11 parts, Semen Vaccariae 22 parts, Spica Prunellae 32 parts.
The above-mentioned application of Chinese medicine in preparation treatment penile induration disease drug for induration of penis.
The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.
The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.
The taboo item of Chinese medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.
Chinese medicine composition of the present invention has benefiting QI for activating blood circulation, and effect of note of the ancient Chinese of disappearing of reducing phlegm, for induration of penis.
Of the present inventionly be Chinese Pharmacopoeia 2010 editions 1 kinds recorded for crude drug each in the Chinese medicine of induration of penis.
Induration of penis is generally controlled mainly with stagnation of liver-QI opinion of suffering from a deficiency of the kidney.When with qi-blood disharmony, expectorant stasis blocking is stagnant is pathogenesis, and treatment is when with benefiting QI for activating blood circulation, and the note of the ancient Chinese that disappears of reducing phlegm is method.Chinese medicine warming the meridian and activating blood circulation for induration of penis of the present invention use, focus on replenishing vital QI with drugs of warm nature instead of attack the stasis of blood, gas clots absorbing being gone, blood vessels tonneau.Fructus Evodiae, Ramulus Cinnamomi dispelling cold by warming the meridian in prescriptions of Chinese medicine of the present invention, promoting blood circulation, wherein Fructus Evodiae merit arrogates to oneself dispersing cold for relieving pain, and warm promoting blood circulation is longer than by Ramulus Cinnamomi, is monarch drug altogether.Radix Angelicae Sinensis, Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling; Cortex Moutan had both helped all medicine promoting blood circulation to remove blood stasis, and can purify the blood again a point deficiency-heat, was ministerial drug altogether.Colla Corii Asini is sweet flat, and nourishing blood and hemoslasis is nourshing Yin and drynsessmoistening prescription; The Radix Paeoniae Alba is bitter to be slightly cold, and nourish blood yin fluid astringing, easing the affected liver to relieve pain; Radix Ophiopogonis, sweetness and bitterness was slightly cold, replenishing YIN and removing heat.Three medicines share, and nourish blood and adjust liver, nourshing Yin and drynsessmoistening prescription, and clearind deficient heat, and the warm-dryness syndrome of Fructus Evodiae (processed), Ramulus Cinnamomi.Radix Codonopsis, Radix Glycyrrhizae replenishing QI to invigorate the spleen, as a means of the source of vital function, Yin grows while yang is generating, the prosperous blood of gas fills; The Rhizoma Pinelliae, Rhizoma Zingiberis Recens are pungent opens eliminating stagnation, leads to and falls gastric qi, to help blood stasis dispelling; Wherein Rhizoma Zingiberis Recens again stomach warming gas to help biochemistry, and help Fructus Evodiae, Ramulus Cinnamomi with dispelling cold by warming the meridian, be more than adjuvant drug.Radix Glycyrrhizae still can coordinating the actions of various ingredients in a prescription, holds concurrently as making medicine.All medicines share, and play dispelling cold by warming the meridian altogether, the merit of nourishing blood and dissolving stasis.Drug matching feature of the present invention has 21 to be that Fang Zhongwen mends clearly and disappears and use, but takes a tonic or nourishing food to build up one's health based on warming the meridian; Two is group's temperature compensation medicine and a small amount of cold and cool medicine compatibility, can make Quan Fangwen and not dry, coordination of potent and mild therapies, to become the agent of replenishing vital QI with drugs of warm nature blood stasis dispelling.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
For a Chinese medicine for induration of penis, each crude drug weight proportion is as follows:
Fructus Evodiae 5g, Ramulus Cinnamomi 6g, Rhizoma Chuanxiong 6g, Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 15g, Cortex Moutan 9g, Rhizoma Zingiberis Recens 5g, Rhizoma Pinelliae 10g, Radix Ophiopogonis 18g, Radix Codonopsis 15g, Colla Corii Asini 10g, Radix Glycyrrhizae Preparata 9g, Semen Vaccariae 20g, Spica Prunellae 30g.
Embodiment 2
For a Chinese medicine for induration of penis, each crude drug weight proportion is as follows:
Fructus Evodiae 4g, Ramulus Cinnamomi 5g, Rhizoma Chuanxiong 5g, Radix Angelicae Sinensis 8g, Radix Paeoniae Alba 13g, Cortex Moutan 7g, Rhizoma Zingiberis Recens 4g, Rhizoma Pinelliae 8g, Radix Ophiopogonis 16g, Radix Codonopsis 13g, Colla Corii Asini 8g, Radix Glycyrrhizae Preparata 7g, Semen Vaccariae 18g, Spica Prunellae 28g.
Embodiment 3
For a Chinese medicine for induration of penis, each crude drug weight proportion is as follows:
Fructus Evodiae 6g, Ramulus Cinnamomi 7g, Rhizoma Chuanxiong 7g, Radix Angelicae Sinensis 12g, Radix Paeoniae Alba 17g, Cortex Moutan 11g, Rhizoma Zingiberis Recens 6g, Rhizoma Pinelliae 12g, Radix Ophiopogonis 20g, Radix Codonopsis 17g, Colla Corii Asini 12g, Radix Glycyrrhizae Preparata 11g, Semen Vaccariae 22g, Spica Prunellae 32g.
Embodiment 4
For a Chinese medicine for induration of penis, each crude drug weight proportion is as follows:
Fructus Evodiae 3g, Ramulus Cinnamomi 4g, Rhizoma Chuanxiong 4g, Radix Angelicae Sinensis 6g, Radix Paeoniae Alba 11g, Cortex Moutan 5g, Rhizoma Zingiberis Recens 3g, Rhizoma Pinelliae 6g, Radix Ophiopogonis 14g, Radix Codonopsis 11g, Colla Corii Asini 6g, Radix Glycyrrhizae Preparata 5g, Semen Vaccariae 15g, Spica Prunellae 25g.
Embodiment 5
For a Chinese medicine for induration of penis, each crude drug weight proportion is as follows:
Fructus Evodiae 7g, Ramulus Cinnamomi 8g, Rhizoma Chuanxiong 8g, Radix Angelicae Sinensis 14g, Radix Paeoniae Alba 19g, Cortex Moutan 13g, Rhizoma Zingiberis Recens 7g, Rhizoma Pinelliae 14g, Radix Ophiopogonis 22g, Radix Codonopsis 19g, Colla Corii Asini 14g, Radix Glycyrrhizae Preparata 13g, Semen Vaccariae 25g, Spica Prunellae 35g.
Carried out clinical pharrnacokinetics test to the Chinese medicine composition of embodiments of the invention l, Details as Follows:
1. data and method
1.180 routine induration of penis patients, 30 ~ 45 years old age, average 40 years old; The course of disease≤1a has 20 examples, and course of disease > 1a has 60 examples.Without special sense of discomfort when all case penises relax, but all have local pain sense when erecing, the patient that part is serious affects sexual life with phallocampsis.All patient's row color ultrasound examinations, all have abnormal echo, and tuberosity developing size, position are obvious.Scleroma size 0.5 ~ 1.4cm.
1.2 Therapeutic Method give the Chinese medicine composition of the embodiment of the present invention 1, prescription Fructus Evodiae 5g, Ramulus Cinnamomi 6g, Rhizoma Chuanxiong 6g, Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 15g, Cortex Moutan 9g, Rhizoma Zingiberis Recens 5g, Rhizoma Pinelliae 10g, Radix Ophiopogonis 18g, Radix Codonopsis 15g, Colla Corii Asini 10g, Radix Glycyrrhizae Preparata 9g, Semen Vaccariae 20g, Spica Prunellae 30g.Every day 1 dose, wherein Colla Corii Asini molten is taken, and other medicines are decocted in water for oral dose.Taking continuously 2 weeks was 1 course for the treatment of.All avoid during all patient treatments and take pungent stimulation food, spirits and inebriant.
1.3 observation index recoveries from illness: penile induration disappears, and erection pain disappears; Phallocampsis is corrected, and voluptus recovers.Effective: to have following one to be effective, erection pain disappears or improves, and phallocampsis is improved, and scleroma is reduced or softened, voluptus recovery etc.Invalid: above-mentioned symptom and sign are without improvement.
2 results
80 routine patients, clinical 67 example recoveries from illness 2 courses for the treatment of, effectively, 3 examples are invalid for 10 examples.2 course cure rates 83.75%, total effective rate 96.25%.
3. the routine patient of untoward reaction 80 is showed no untoward reaction.

Claims (6)

1., for a Chinese medicine for induration of penis, be made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 3-7 part, Ramulus Cinnamomi 4-8 part, Rhizoma Chuanxiong 4-8 part, Radix Angelicae Sinensis 6-14 part, Radix Paeoniae Alba 11-19 part, Cortex Moutan 5-13 part, Rhizoma Zingiberis Recens 3-7 part, Rhizoma Pinelliae 6-14 part, Radix Ophiopogonis 14-22 part, Radix Codonopsis 11-19 part, Colla Corii Asini 6-14 part, Radix Glycyrrhizae Preparata 5-13 part, Semen Vaccariae 15-25 part, Spica Prunellae 25-35 part.
2. the Chinese medicine for induration of penis according to claim 1, is characterized in that, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 4-6 part, Ramulus Cinnamomi 5-7 part, Rhizoma Chuanxiong 5-7 part, Radix Angelicae Sinensis 8-12 part, Radix Paeoniae Alba 13-17 part, Cortex Moutan 7-11 part, Rhizoma Zingiberis Recens 4-6 part, Rhizoma Pinelliae 8-12 part, Radix Ophiopogonis 16-20 part, Radix Codonopsis 13-17 part, Colla Corii Asini 8-12 part, Radix Glycyrrhizae Preparata 7-11 part, Semen Vaccariae 18-22 part, Spica Prunellae 28-32 part.
3. the Chinese medicine for induration of penis according to claim 2, is characterized in that, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 5 parts, Ramulus Cinnamomi 6 parts, Rhizoma Chuanxiong 6 parts, Radix Angelicae Sinensis 10 parts, the Radix Paeoniae Alba 15 parts, Cortex Moutan 7-11 part, 5 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 10 parts, Radix Ophiopogonis 18 parts, Radix Codonopsis 15 parts, 10 parts, Colla Corii Asini, Radix Glycyrrhizae Preparata 9 parts, Semen Vaccariae 20 parts, Spica Prunellae 30 parts.
4. the Chinese medicine for induration of penis according to claim 2, is characterized in that, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 4 parts, Ramulus Cinnamomi 5 parts, Rhizoma Chuanxiong 5 parts, Radix Angelicae Sinensis 8 parts, the Radix Paeoniae Alba 13 parts, Cortex Moutan 7 parts, 4 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 8 parts, Radix Ophiopogonis 16 parts, Radix Codonopsis 13 parts, 8 parts, Colla Corii Asini, Radix Glycyrrhizae Preparata 7 parts, Semen Vaccariae 18 parts, Spica Prunellae 28 parts.
5. the Chinese medicine for induration of penis according to claim 2, is characterized in that, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Fructus Evodiae 6 parts, Ramulus Cinnamomi 7 parts, Rhizoma Chuanxiong 7 parts, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 17 parts, Cortex Moutan 11 parts, 6 parts, Rhizoma Zingiberis Recens, the Rhizoma Pinelliae 12 parts, Radix Ophiopogonis 20 parts, Radix Codonopsis 17 parts, 12 parts, Colla Corii Asini, Radix Glycyrrhizae Preparata 11 parts, Semen Vaccariae 22 parts, Spica Prunellae 32 parts.
6. the application of Chinese medicine in preparation treatment penile induration disease drug for induration of penis described in the arbitrary claim of claim 1-5.
CN201510511758.6A 2015-08-20 2015-08-20 Traditional Chinese medicine for Peyronie's disease Pending CN105056188A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102716452A (en) * 2012-06-18 2012-10-10 李承平 Group of channel warming and coldness expelling tablet
CN103656600A (en) * 2013-12-22 2014-03-26 青岛琴诚医药技术有限公司 Preparation method and application of twelve body channel warming pellet
CN103705632A (en) * 2013-12-27 2014-04-09 孟小斐 Application of mammary aggregation dispersing tablets in preparation of medicines for treating penis hardening disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102716452A (en) * 2012-06-18 2012-10-10 李承平 Group of channel warming and coldness expelling tablet
CN103656600A (en) * 2013-12-22 2014-03-26 青岛琴诚医药技术有限公司 Preparation method and application of twelve body channel warming pellet
CN103705632A (en) * 2013-12-27 2014-04-09 孟小斐 Application of mammary aggregation dispersing tablets in preparation of medicines for treating penis hardening disease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
戴西湖: "《男科辨病专方专药治疗学》", 31 May 2007, 军事医学科学出版社 *
陶勇军: "温经汤治疗乳腺增生症45例", 《中国中医药现代远程教育》 *

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Application publication date: 20151118