KR20170133714A - Chinese medicine ointment - Google Patents

Abstract

Disclosed is a medicinal herb-based ointment for treating prostatitis, containing the following ingredients: 10-25 parts by weight of Radix Bupleuri, 10-25 parts by weight of Rhizoma Anemarrhenae, 3-11 parts by weight of Fructus Gardeniae, 3-11 parts by weight of Lycium barbarum, 3-11 parts by weight of Radix Paeoniae Rubra, and 3-11 parts by weight of Flos Chrysanthemi.

Description

Chinese medicine ointment

The present invention relates to a herbal ointment for treating prostatitis belonging to the field of oriental medicine.

Prostatitis is a common adult male reproductive organs disease that is predominantly in the young and elderly population and is characterized by frequent urination, urgent urination, odynuria, paruria, endless micturition desire, , Urinary retention after voiding, overflow of the prostate fluid, presence of viscin thread and liquid in the urethral area, pain and pendant sensation in the anus position (to different levels), testicular annular pain, , Back pain, and sexual dysfunction (such as erectile dysfunction, premature ejaculation, etc.). Prostatitis has the effect of removing heat and toxic substances by boosting the energy of the kidneys, strengthening the quantity (YANG), promoting blood circulation, removing congestion, promoting diuretic and introducing turbidity Which is usually treated by conventional treatment methods. There are various prior arts for treating prostatitis, including oral administration, herbal medicine used for external use, herbal medicine, and a mixed preparation of herbal medicine and herbal medicine. The drug can be used to promote blood circulation to remove congestion, to clean the heart, to promote diuretic, to reduce inflammation, to relieve pain, to treat pain urination, and to promote diuretic . However, currently, there is no specific drug for the treatment of prostatitis, and the therapeutic effect of the drug in the prior art is unsatisfactory.

Therefore, there is still a need for herbal preparations that have a better therapeutic effect in the treatment of prostatitis. Until now, there is no data that can deny the novelty of the present invention. In order to obtain herbal preparations having a better effect on the treatment of prostatitis, the inventors of the present invention collected vast clinical observation data by conducting elaborate research for many years through clinical application and repeated verification, thereby completing the present invention .

It is an object of the present invention to provide an ointment for treatment of prostatitis having an immediate effect.

The present invention is realized as follows: The herbal ointment for treating prostatitis includes the following ingredients: Radix Bupleuri, Rhizoma Anemarrhenae, Fructus Gardeniae, Lycium barbarum, peony Radix Paeoniae Rubra), and Chrysanthemi (Flos Chrysanthemi); In order to obtain a better therapeutic effect, the raw materials can be combined with Dandelion and Radix Curcumae; In order to obtain better therapeutic effect, Poria cocos can be added.

The herbal ointment of the present invention containing raw materials within the following ranges has excellent therapeutic effects:

10-25 parts by weight of Seishi, 10-25 parts by weight of gum, 3-11 parts by weight of gardenia, 3-11 parts by weight of ginger, 3-11 parts by weight of peony root, and 3-11 parts by weight of chrysanthemum flower.

Preferably, 15 parts by weight of Seicho, 15 parts by weight of gum, 5 parts by weight of gardenia, 5 parts by weight of ginger, 5 parts by weight of peony root, and 5 parts by weight of chrysanthemum flower.

The ointment of the present invention may also contain ingredients in the following ranges: 10-25 parts by weight of Seal, 10-25 parts by weight of gum, 3-11 parts by weight of gardenia, 3-11 parts by weight of ginger, 3- 11 to 3 parts by weight of chrysanthemum flowers, 3 to 15 parts by weight of dandelion, and 3 to 11 parts by weight of chestnut.

Preferably, 15 parts by weight of Seishi, 15 parts by weight of ginger, 5 parts by weight of gardenia, 5 parts by weight of ginger, 5 parts by weight of ginger, 5 parts by weight of chrysanthemum flower, 7.5 parts by weight of dandelion and 5 parts by weight of ginger.

The ointment of the present invention may also contain ingredients in the following ranges: 10-25 parts by weight of Seal, 10-25 parts by weight of gum, 3-11 parts by weight of gardenia, 3-11 parts by weight of ginger, 3- And 3 to 11 parts by weight of chrysanthemum flowers, 3 to 15 parts by weight of dandelion and 3 to 11 parts by weight of cormorant, and 5 to 20 parts by weight of gypsum.

Preferably, 15 parts by weight of Seishi, 15 parts by weight of ginger, 5 parts by weight of gardenia, 5 parts by weight of ginger, 5 parts by weight of peony powder, 5 parts by weight of chrysanthemum flower, 7.5 parts by weight of dandelion, 5 parts by weight of ginger, .

In principle, the preparation of the herbal composition of the present invention is carried out according to the method described in Technical requirements for study of new traditional Chinese medicine technology (ZHONG YAO XIN YAO ZHI BEI GONG YI YAN JIU DE JI SHU YAO QIU) This method includes: making use of current recipe technologies to make APIs the materials used for ointment, drying them under the sun, crushing them to over 200 mesh, and adding some additives such as medical vaseline to make ointments May act directly at the prostate location of the anus rectum. The present invention may also have other dosage forms such as topical suppositories.

The dose of the herbal ointment of the present invention is about 2-4 g (once a doctor's instruction depending on the severity of the disease) twice a day for 5 days of treatment. After 1 to 2 times of treatment, it is possible to obtain a therapeutic effect substantially, and clinically recovering effect can be obtained after further strengthening therapy of 1-2 times of treatment. In clinical validation, the recurrence rate of the present invention was low.

The herbal ointment of the present invention acts directly at the prostate position of the anus, rapidly penetrates into the prostate gland, promotes blood circulation, removes congestion, cleanses the heart, promotes diuresis, reduces inflammation , To relieve pain, to treat pain urination, to promote diuretic, thereby eliminating germs and eliminating inflammation quickly.

The present invention will be described in more detail by clinical observation tests and examples.

Example 1 copy  Manufacture of an ointment of invention

Weigh the raw materials as follows: 15 parts by weight of Seiho, 15 parts by weight of gum, 5 parts by weight of gardenia, 5 parts by weight of ginger, 5 parts by weight of peony root, and 5 parts by weight of chrysanthemum flower.

Example  2

7.5 parts by weight of dandelion and 5 parts by weight of corn were added based on Example 1.

Example  3

10 parts by weight of Bokryo was added based on Example 2.

In principle, the preparation of the herbal composition of the present invention is carried out according to the method described in Technical requirements for study of new traditional Chinese medicine technology (ZHONG YAO XIN YAO ZHI BEI GONG YI YAN JIU DE JI SHU YAO QIU) These methods include: making the APIs into materials for ointment using current recipe technology, drying them under sunlight, pulverizing them to over 200 mesh, and adding medical vaseline to ointment.

Example  4 Preparation of herbal suppositories of the present invention

Weigh the raw materials as follows: 15 parts by weight of Seiho, 15 parts by weight of gum, 5 parts by weight of gardenia, 5 parts by weight of ginger, 5 parts by weight of peony root, and 5 parts by weight of chrysanthemum flower.

Example  5

7.5 parts by weight of dandelion and 5 parts by weight of corn were added based on Example 4.

Example  6

10 parts by weight of Bamboo is added based on Example 5.

In principle, the preparation of the herbal suppositories of the present invention is carried out according to the method described in the technical requirements for study of new traditional Chinese medicine technology (ZHONG YAO XIN YAO ZHI BEI GONG YI YAN JIU DE JI SHU YAO QIU) These methods include: making the APIs into materials for ointment using current recipe techniques, drying them under sunlight, pulverizing them to over 200 mesh, adding some additives to the soluble one-part suppositories I make it.

Test 1 Clinical treatment effect observation data

1. Clinical data

A total of 281 patients were selected, including 36 patients aged less than 30 years, 55 patients aged 30-35 years, 68 patients aged 35-40 years, 80 patients aged 40-45 years, 42 patients; The oldest patient is 70 years old, the youngest patient is 21 years old; 49 were single, 232 were married; There were 43 patients with a history of 6 months or less, 144 patients with a history of 6 to 12 months, 56 patients with a history of 12-18 months, There are 38 patients.

2. Diagnostic Criteria

(1) Major clinical symptoms include: frequent urination, urgent urination, voiding cessation, urinary incontinence, irregular urination, urethral itching, urinary retention, urination of the prostate fluid, presence of drops and fluid in the urethra, Pain and pendant impingement (at different levels), testicular annular pain, secret site swelling, back pain, and sexual dysfunction (such as erectile dysfunction, premature ejaculation, etc.).

(2) Prostate fluid test: the body's lectin level is reduced, and at all high power fields the leukocyte count is above 10 or the "pyocyte" level is above "+".

(3) Bacteria testing: 110 patients are examined by performing bacterial culture, counting, and drug susceptibility testing according to the Meares method, in which 72 patients are suffering from pathogenic bacterial attacks; 38 patients were not exposed to pathogenic bacteria.

3. Methods of treatment: According to the etiology and pathogenesis of prostatitis, the raw materials contained in one of the present invention are dried in the sun, pulverized to a size exceeding 200 mesh, made into ointment by adding some additives (for example, medical vaseline) The ointment of the present invention is applied directly to the anus of the anal prostate at a dose of 2-4 g once every two days with a 5-day treatment schedule (according to the physician's instruction according to the severity of the disease). After 1 to 2 times of treatment, it is possible to obtain the therapeutic effect substantially. Therapeutic effect can be obtained clinically after the additional treatment of 1-2 times of the treatment.

4. Criteria for evaluation of therapeutic effect

Recovery: Clinical symptoms disappear, and in all high power fields the leukocyte count is less than 10, and the body's lectin levels return to normal.

Significant effects: Clinical symptoms are substantially or significantly relieved, appear approximately normal in the prostate fluid examination, and there is no significant prostate contact pain.

Improvement: The subjective symptoms disappear or are significantly relieved, there is no tenderness, the leukocyte count is significantly reduced in the prostate fluid examination, and the body's lectin level is increased or substantially normal.

No effect: After two or more treatment courses, the symptoms are not significantly relieved and there is no significant change in the relevant index.

5. Treatment Results

After 1-2 courses of treatment with conventional therapy, clinical symptoms can be relieved quickly. The number of recovery patients was 140 (49.8%), and the number of patients showing significant effect was 51.1 (18.1%), the improvement was 34 (12.1%), (20%); Therefore, the overall effectiveness rate is 80%.

After 1-2 courses of treatment with additional intensive therapy, clinical symptoms disappear quickly, and the constitution returns to normal. The number of patients recovered was 168 (59.8%), and the number of patients showing a significant effect was 62 (22.1%). The number of patients showing improvement was 39 (13.9%), (4.2%); Therefore, the overall effectiveness rate is 95.8%.

Claims (5)

10 to 25 parts by weight of Radix Bupleuri, 10 to 25 parts by weight of Rhizoma Anemarrhenae, 3 to 11 parts by weight of Fructus Gardeniae, Lycium barbarum, 3-11 parts by weight of Radix Paeoniae Rubra, 3-11 parts by weight of Radix Paeoniae Rubra and 3-11 parts by weight of Flos Chrysanthemi. The ointment preparation for treating prostatitis according to claim 1, which comprises 15 parts by weight of Seicho, 15 parts by weight of gum, 5 parts by weight of gardenia, 5 parts by weight of ginger, 5 parts by weight of peony powder, and 5 parts by weight of chrysanthemum flower. The ointment according to claim 1 further comprising: 3-15 parts by weight of Dandelion and 3-11 parts by weight of Radix Curcumae for the treatment of prostatitis. The ointment according to claim 3, which comprises 15 parts by weight of Seishi, 15 parts by weight of gum, 5 parts by weight of gardenia, 5 parts by weight of ginger, 5 parts by weight of peony powder, 5 parts by weight of chrysanthemum flower, 7.5 parts by weight of dandelion and 5 parts by weight of corn. The ointment according to claim 3, further comprising: 5-20 parts by weight of Poria cocos for the treatment of prostatitis.