CN103705897A - Cancer pain-relieving plaster - Google Patents
Cancer pain-relieving plaster Download PDFInfo
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- CN103705897A CN103705897A CN201410003041.6A CN201410003041A CN103705897A CN 103705897 A CN103705897 A CN 103705897A CN 201410003041 A CN201410003041 A CN 201410003041A CN 103705897 A CN103705897 A CN 103705897A
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Abstract
The invention discloses a cancer pain-relieving plaster prepared by a preparation A and a preparation B, wherein the preparation A is prepared by five branches, five skins, one brick, one stone, five cores, and the like; the preparation B is prepared by poria cocos, pinellia ternate, jackinthepulpit tuber rhizome, trichosanthes kirilowii maxim, centipede, zaocys dhumnade, and the like. When the cancer pain-relieving plaster is prepared, the preparation B is added into the preparation A to be decocted for 4.5-5.5 hours, red lead is added to be mixed to pasty fluid, then cold water is added for steeping to releasing fire-toxin, water is changed once one day, and the plaster is obtained after steeping for 7 days. When the plaster is used, the plaster is coated on cotton cloth or plaster paster. The cancer pain-relieving plaster mainly aims at tumour cancers of lung cancer, gastric cancer, liver cancer, pancreatic cancer, colon caner, rectal caner, kidney cancer, bladder caner, breast cancer, cervical cancer, ovarian cancer, esophagus cancer, laryngeal cancer, and the like and is obvious in pain-relieving effect.
Description
Technical field
The present invention relates to a kind of cancer plaster that relieves the pain.
Background technology
Cancer is the general designation of a large class malignant tumor.The feature of cancerous cell be unrestrictedly, hypertrophy without end, the nutrient substance in patient body is consumed in a large number; Cancerous cell discharges multiple toxin, makes human body produce series of symptoms; Cancerous cell also can be transferred to whole body growth and breeding everywhere, cause that human body is become thin, unable, anemia, inappetence, heating and serious organ function impaired etc.
Cancer patient be generally difficult to cure, and during one's sickness, patient part can be attended by pain in various degree, to patient, has brought huge human body misery and psychic pain, also to family numbers of patients, has brought huge psychic pain simultaneously.At present, the not a kind of pharmaceutical preparation that can effectively alleviate pain among cancer patients.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of cancer plaster that relieves the pain, can obviously alleviate the pain causing because of cancer.
The present invention is achieved by the following technical solutions:
The cancer plaster that relieves the pain, is made by A preparation and B preparation, and wherein, A preparation is made by following component:
Five: Ramulus Persicae, Ramulus Salicis Babylonicae, Ramulus sophorae, Ramulus ulmi pumilae, Ramulus Mori, each 15～25 grams, preferred, each 20 grams;
Five skins: Cortex Pini, Cortex Jujubae, tangerine skin, bark of Toona sinensis, Cortex Juglandis, each 25～35 grams, preferred, each 30 grams;
One brick: 1000 ± 50 grams of blue bricks;
One stone: 2000 ± 50 grams of limestone;
Five cores: almond, Semen Persicae, Semen Jujubae, Semen Litchi, Fructus Citri tangerinae core, each 50 ± 3 grams;
Described B preparation is made by following crude drug:
15 ± 2 grams, Poria, 20 ± 2 grams of the Rhizoma Pinelliaes, 18 ± 2 grams of Rhizoma Arisaematis, 15 ± 2 grams of Fructus Trichosanthis, 20 ± 2 grams, Rhizoma Gastrodiae, 12 ± 2 grams of Semen Coiciss, 10 ± 2 grams of Squama Manis, 25 ± 2 grams of the Radixs Angelicae Dahuricae, 30 ± 2 grams of Herba Scutellariae Barbataes, 20 ± 2 grams of Radix Angelicae Sinensis, 30 ± 2 grams of Rhizoma Chuanxiongs, 15 ± 2 grams of Radix Paeoniae Rubra, 20 ± 2 grams, the Radix Rehmanniae, 10 ± 2 grams, Semen Persicae, 20 ± 2 grams, Flos Carthami, 15 ± 2 grams of Rhizoma Curcumae, 50 ± 2 grams of Eupolyphaga Seu Steleophagas, 20 ± 2 grams of Pheretimas, 20 ± 2 grams of Bombyx Batryticatus, 30 ± 2 grams of Fructus Xanthii, 15 ± 2 grams of Rhizoma Dioscoreae Bulbiferaes, 10 ± 2 grams of Thallus Laminariae (Thallus Eckloniae)s, 25 ± 2 grams, Radix Rehmanniae Preparata, 30 ± 2 grams of Rhizoma Dioscoreaes, 15 ± 2 grams of Fructus Corni, 15 ± 2 grams of Cortex Cinnamomis, 20 ± 2 grams of Rhizoma Zingiberis Preparatums, 25 ± 2 grams of Fructus Lyciis, 20 ± 2 grams of Colla cornus cervis, 20 ± 2 grams of Colla Plastri Testudinis, 50 ± 2 grams of Herba Epimedii, 20 ± 2 grams of Radix Aconiti Lateralis Preparata, 30 ± 2 grams of Radix Rumiciss, 15 ± 2 grams of Polyporus, 15 ± 2 grams of Pseudobulbus Cremastrae Seu Pleioness, 20 ± 2 grams of Radix Asparagis, 30 ± 2 grams of Radix Sophorae Tonkinensiss, 80 ± 2 grams of the Radixs Astragali, 30 ± 2 grams of the Rhizoma Atractylodis Macrocephalaes, 20 ± 2 grams of Rhizoma Imperataes, 25 ± 2 grams of the Rhizoma Anemarrhenaes, 20 ± 2 grams of Radix Scrophulariaes, 30 ± 2 grams of Concha Ostreaes, 20 ± 2 grams of Spica Prunellaes, 100 ± 2 grams of Rhizoma Paridis, 30 ± 2 grams of Hedyotidis Diffusaes, 30 ± 2 grams of Radix Et Caulis Acanthopanacis Senticosis, 50 ± 2 grams, Fructus Jujubae, 20 ± 2 grams of Fructus Ligustri Lucidi, 15 ± 2 grams of Herba Taxillis, 30 ± 2 grams of Rhizoma Coptidis, 20 ± 2 grams of Radix Salviae Miltiorrhizaes, 30 ± 2 grams of Cortex Moutans, 30 ± 2 grams of Flos Loniceraes, 50 ± 2 grams of Rhizoma Polygoni Cuspidati, 20 ± 2 grams of Radix Gentianaes, 30 ± 2 grams of Radix Bupleuri, 50 ± 2 grams of Herba Leonuris, 20 ± 2 grams of Herba Scutellariae Barbataes, 30 ± 2 grams of Rhizoma Corydalis, 25 ± 2 grams of Oletum Trogopteroris, 30 ± 2 grams of Radix Platycodoniss, 20 ± 2 grams of Fructus Aurantii Immaturuss, 30 ± 2 grams of Olibanums, 50 ± 2 grams of Myrrhas, 150 ± 2 grams of Aspongopuss, 15 ± 2 grams of Radixs Stephaniae Tetrandrae, 20 ± 2 grams of Herba Solani Nigris, 30 ± 2 grams of Herba Patriniae, 20 ± 2 grams of Radix Curcumaes, 30 ± 2 grams of Aloes, 20 ± 2 grams of Radix Codonopsis, 30 ± 2 grams of Rhizoma Cimicifugaes, 20 ± 2 grams of Cortex Phellodendris, 30 ± 2 grams of Rhizoma Atractylodis, 15 ± 2 grams of Fructus Gardeniaes, 30 ± 2 grams of Herba Solani Lyratis, 30 ± 2 grams of Ramulus Euonymis, 50 ± 2 grams of Folium cordylines fruticosaes, 30 ± 2 grams of Herba Violaes, 30 ± 2 grams of Herba Taraxacis, 50 ± 2 grams of Radix Notoginseng, 100 ± 2 grams of Semen Vaccariae, 15 ± 2 grams of ghost thorns, 30 ± 2 grams of Herba Cistanches, 30 ± 2 grams, Fructus Foeniculi, 50 ± 2 grams of Herba Salviae Chinensiss, 30 ± 2 grams of Herba Selaginellae Doederleiniis, thousand 60 ± 2 grams of Cutis Bufonis, 30 ± 2 grams of Herba Sarcandraes, 20 ± 2 grams of Herba Duchesneae Indicaes, 15 ± 2 grams of Ganodermas, 30 ± 2 grams of Radix Gentianaes, 20 ± 2 grams of field thistles, 30 ± 2 grams of Radix Arnebiae (Radix Lithospermi)s, 50 ± 2 grams of Fructus Akebiaes, 30 ± 2 grams of Hirudos, 15 ± 2 grams of Herba Artemisiae Scopariaes, 30 ± 2 grams of Pericarpium Citri Reticulataes, 20 ± 2 grams of Pheretimas, 300 ± 10 grams of Scolopendras, 100 ± 2 grams of Scorpios, 400 ± 20 grams of Zaocyss, 20 ± 2 grams of Herba Galii Teneri, 25 ± 2 grams of Radix Adenophoraes, 30 ± 2 grams of Radix Glehniaes, 20 ± 2 grams of Radix Ophiopogonis, 30 ± 2 grams of Fructus Schisandrae Chinensis, 50 ± 2 grams of Nidus Vespaes, 20 ± 2 grams of Periostracum Serpentiss, 20 ± 2 grams, Flos Sophorae, 15 ± 2 grams of Gypsum Fibrosum, 15 ± 2 grams of GUANGXIANG, 19 ± 2 grams of Fructus Camptothecae Acuminatae, 20 ± 2 grams of Flos Inulae, 20 ± 2 grams of Rhizoma Phragmitis, 30 ± 2 grams of Herba Schizonepetae, 20 ± 2 grams of Fructus Arctiis, 15 ± 2 grams of Rhizoma Polygonati Odorati, 20 ± 2 grams of Lasiosphaera Seu Calvatia, 15 ± 2 grams of Boraxs, , 20 ± 2 grams of Fructus Mumes, 10 ± 2 grams of Haematitums, 50 ± 2 grams of Catharsii molossis, 20 ± 2 grams of Fructus Forsythiaes, 30 ± 2 grams of Flos Magnoliaes, 30 ± 2 grams of Radix Isatidis, 20 ± 2 grams of Rhizoma Et Radix Notopterygiis, 30 ± 2 grams of Herba Houttuyniae, 20 ± 2 grams of the Fructus Kochiae, 30 ± 2 grams of Radix Scutellariaes, 20 ± 2 grams of Herba Centipedae, 50 ± 2 grams of Rhizoma Dioscoreae Nipponicae, 20 ± 2 grams, Radix Glycyrrhizae, 15 ± 2 grams of Indigo Naturaliss, 500 ± 2 grams of Borneolum Syntheticums, 20 ± 2 grams of Semen Cuscutae, 30 ± 2 grams of Radix Saposhnikoviaes, 30 ± 2 grams of Rhizoma Homalomenaes, 20 ± 2 grams of Cortex Lycii, 20 ± 2 grams of Radix Dipsacis, 30 ± 2 grams of Radix Aconiti Preparatas, 30 ± 2 grams of Radix Cyathulaes, 20 ± 2 grams of Radix Angelicae Pubescentiss, 20 ± 2 grams of Rhizoma Alismatis, 50 ± 2 grams of Herba speranskiae tuberculataes, 30 ± 2 grams of Semen Strychni, 20 ± 2 grams of Caulis Spatholobis, 30 ± 2 grams of Radix Cynanchi Paniculatis, 15 ± 2 grams of Rhizoma Sparganii, 20 ± 2 grams of Cortex erythrinaes, 2000 ± 2 grams of Gallus Domesticuss, 20 ± 2 grams of Ramulus Cinnamomi, 15 ± 2 grams, Herba Ephedrae, 30 ± 2 grams of Flos Daturae, 50 ± 2 grams of Geckos, 20 ± 2 grams of Folium Isatidiss, 5 ± 0.5 kilograms, Oleum Sesami, 2 ± 0.5 kilograms of Plumbum preparatium, 50 ± 2 grams, Moschus.
The preparation method of described A preparation is: gets each component, pulverizes, mix, add water to submerge, soak 20～25 hours, decoct with water 2.5～3.5 hours, filter, obtain medicine juice, be A preparation, and standby.
The preparation method of described B preparation is: gets each crude drug except Oleum Sesami, Plumbum preparatium, pulverizes, mix, add Oleum Sesami submergence, soak 45～50 hours, be then fried, after medicine is withered and yellow, pull medicinal residues out, obtain medicine oil, be B preparation, and standby.
The relieve the pain preparation method of plaster of described cancer is: above-mentioned B preparation is added in A preparation, decoct 4.5～5.5 hours, lower Plumbum preparatium, stir into mastic, then add cold water (4～20 ℃ of temperature) to soak releasing fire-toxin, within one day, change water once, soak after 7 days, obtain plaster, during use, plaster is coated on cotton or plaster paster.
During treatment, in conjunction with patient's disease, aim at affected area, symmetrical each in front and back one forced on, 7 days courses for the treatment of (efficacy of a drug effect duration of forcing on is about 7 days).Add soak winter and get final product (while having a bath, peel, wash again and stick).General patient with advanced cancer, on plaster after, patient can have the sensation that slows down pain during 8 hours to 24 hours.The plaster efficacy of a drug of the present invention is unique lastingly, auxiliary without other antalgicas.The analgesic effect of plaster of the present invention, is not only embodied in and alleviates patient's pain, improves patient's mental attitude, extends the aspects such as patient's life-span, also can bring many convenience and spiritual comfort to patients' relatives.
Described Ramulus sophorae refers to the branch of Chinese scholar tree.Described Ramulus Persicae, Ramulus Salicis Babylonicae, Ramulus ulmi pumilae, Ramulus Mori are respectively the common branch of peach tree, willow, elm, mulberry, and its implication is known by general population.
Described Cortex Pini, Cortex Jujubae, tangerine skin, bark of Toona sinensis, Cortex Juglandis are respectively the bark of pinaster, jujube tree, tangerine, bark of Toona sinensis, walnut, and its implication is known by general population.
Described almond, Semen Persicae, Semen Jujubae, Semen Litchi, Fructus Citri tangerinae core are respectively the core of Fructus Pruni, Fructus Persicae, Fructus Jujubae, Fructus Litchi, Fructus Citri tangerinae (being fruit), and its implication is known by general population.
Described thousand Cutis Bufonis, form flavor efficacy for Bufonidae animal Bufo siccus or the skin that it plants Bufo siccus of the same race dry: sweet in the mouth, pungent, and cool in nature, slightly poisonous.Subduing swelling and detoxicating, pain relieving diuresis.Clinical practice: this product is applicable to kinds of tumors, as hepatocarcinoma, pulmonary carcinoma, gastric cancer, malignant lymphoma, intestinal cancer, the esophageal carcinoma, leukemia etc.; External treatment skin carcinoma, cervical cancer, breast carcinoma etc.
Described Colla cornus cervi, Colla Plastri Testudinis are all existing conventional products in prior art, can buy and obtain from the market.
The cancer of the present invention plaster that relieves the pain, mainly for tumor and cancers such as pulmonary carcinoma, gastric cancer, hepatocarcinoma, cancer of pancreas, colon and rectum carcinoma, renal carcinoma, bladder cancer, breast carcinoma, cervical cancer, ovarian cancer, esophageal carcinoma, laryngeal carcinoma, analgesic effect is obviously (although the pathogenesis of various cancers, the method for the treatment of rule for the treatment of are different, but, the cancer of the present invention plaster that relieves the pain, effect is the pain relieving that relieves the pain, and is not treatment cancer, so the pain that most cancers are brought is all effective).The pain that cancer is brought is a kind of specific type of pain, is middle and terminal cancer patient's common sympton, and the cause of disease is directly related with malignant tumor.From Point of View of Clinical, the pathogenic characteristic of the pain that cancer is brought is simulataneous insufficiency and excessive, " void " duty in healthy energy damage, " reality " is the stagnation of QI, blood stasis etc., treatment general provisions are strengthening vital QI to eliminate pathogenic factors, to lead to pain relieving.Cancer of the present invention relieves the pain plaster in conjunction with cancer middle and advanced stage patient's different pain symptoms, and strengthening vital QI to eliminate pathogenic factors, consolidates and radically reform, having a respite is stagnant, disperses pathogenic wind toxic, hard masses softening and resolving, clearing away heat and nourishing YIN, blood circulation and removing stasis, replenishing QI to invigorate the spleen, benefiting qi and nourishing blood, the damp eliminating of dispeling cold, broken silt relieves the pain, dispersing the stagnated liver-QI for regulating the stomach, warming and recuperating the kidney-YANG, takes into account punching and appoints detoxification and promoting urination, relieving spasm by calming endogenous wind.
Advanced Carcinoma Patient is in pain during the phase, the Therapeutic Method of most of hospitals is the sincere Shandong of injection fourth, morphine etc., and the analgesic effect of these injectable drugs is of short duration, if patient often injects, side effect is very big, concerning patient's disease, make the matter worse beyond doubt, and from the beginning every days two pin develop into every days ten in later stage pin not etc., use in a large number, patients with terminal absorbability extreme difference now, " short, flat, fast " quick-acting costs that relieve the pain are large, and expend energy on, can not produce analgesic effect lastingly.Use the cancer of the present invention plaster that relieves the pain, maximum feature is that the time of relieving the pain is lasting, and the efficacy of a drug is played stably, and has no side effect, and the tumor lump of patients with terminal is also had to the important function of certain inhibition diffusion.The cancer of the present invention plaster that relieves the pain, by percutaneous drug delivery, can solve and the having an intense pain of reduction of patient, and the spirit and the human body that alleviate patient are painful, and the rapid diffusion of tumor is played to good inhibitory action, realize the double effects that relieves the pain and treat conditioning.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment prepares the cancer plaster that relieves the pain
By A preparation and B preparation, made, wherein, A preparation is made by following component:
Five: Ramulus Persicae, Ramulus Salicis Babylonicae, Ramulus sophorae, Ramulus ulmi pumilae, Ramulus Mori, each 20 grams;
Five skins: Cortex Pini, Cortex Jujubae, tangerine skin, bark of Toona sinensis, Cortex Juglandis, each 30 grams;
One brick: 1000 grams of blue bricks;
One stone: 2000 grams of limestone;
Five cores: almond, Semen Persicae, Semen Jujubae, Semen Litchi, Fructus Citri tangerinae core, each 50 grams;
Described B preparation is made by following crude drug:
15 grams, Poria, 20 grams of the Rhizoma Pinelliaes, 18 grams of Rhizoma Arisaematis, 15 grams of Fructus Trichosanthis, 20 grams, Rhizoma Gastrodiae, 12 grams of Semen Coiciss, 10 grams of Squama Manis, 25 grams of the Radixs Angelicae Dahuricae, 30 grams of Herba Scutellariae Barbataes, 20 grams of Radix Angelicae Sinensis, 30 grams of Rhizoma Chuanxiongs, 15 grams of Radix Paeoniae Rubra, 20 grams, the Radix Rehmanniae, 10 grams, Semen Persicae, 20 grams, Flos Carthami, 15 grams of Rhizoma Curcumae, 50 grams of Eupolyphaga Seu Steleophagas, 20 grams of Pheretimas, 20 grams of Bombyx Batryticatus, 30 grams of Fructus Xanthii, 15 grams of Rhizoma Dioscoreae Bulbiferaes, 10 grams of Thallus Laminariae (Thallus Eckloniae)s, 25 grams, Radix Rehmanniae Preparata, 30 grams of Rhizoma Dioscoreaes, 15 grams of Fructus Corni, 15 grams of Cortex Cinnamomis, 20 grams of Rhizoma Zingiberis Preparatums, 25 grams of Fructus Lyciis, 20 grams of Colla cornus cervis, 20 grams of Colla Plastri Testudinis, 50 grams of Herba Epimedii, 20 grams of Radix Aconiti Lateralis Preparata, 30 grams of Radix Rumiciss, 15 grams of Polyporus, 15 grams of Pseudobulbus Cremastrae Seu Pleioness, 20 grams of Radix Asparagis, 30 grams of Radix Sophorae Tonkinensiss, 80 grams of the Radixs Astragali, 30 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Rhizoma Imperataes, 25 grams of the Rhizoma Anemarrhenaes, 20 grams of Radix Scrophulariaes, 30 grams of Concha Ostreaes, 20 grams of Spica Prunellaes, 100 grams of Rhizoma Paridis, 30 grams of Hedyotidis Diffusaes, 30 grams of Radix Et Caulis Acanthopanacis Senticosis, 50 grams, Fructus Jujubae, 20 grams of Fructus Ligustri Lucidi, 15 grams of Herba Taxillis, 30 grams of Rhizoma Coptidis, 20 grams of Radix Salviae Miltiorrhizaes, 30 grams of Cortex Moutans, 30 grams of Flos Loniceraes, 50 grams of Rhizoma Polygoni Cuspidati, 20 grams of Radix Gentianaes, 30 grams of Radix Bupleuri, 50 grams of Herba Leonuris, 20 grams of Herba Scutellariae Barbataes, 30 grams of Rhizoma Corydalis, 25 grams of Oletum Trogopteroris, 30 grams of Radix Platycodoniss, 20 grams of Fructus Aurantii Immaturuss, 30 grams of Olibanums, 50 grams of Myrrhas, 150 grams of Aspongopuss, 15 grams of Radixs Stephaniae Tetrandrae, 20 grams of Herba Solani Nigris, 30 grams of Herba Patriniae, 20 grams of Radix Curcumaes, 30 grams of Aloes, 20 grams of Radix Codonopsis, 30 grams of Rhizoma Cimicifugaes, 20 grams of Cortex Phellodendris, 30 grams of Rhizoma Atractylodis, 15 grams of Fructus Gardeniaes, 30 grams of Herba Solani Lyratis, 30 grams of Ramulus Euonymis, 50 grams of Folium cordylines fruticosaes, 30 grams of Herba Violaes, 30 grams of Herba Taraxacis, 50 grams of Radix Notoginseng, 100 grams of Semen Vaccariae, 15 grams of ghost thorns, 30 grams of Herba Cistanches, 30 grams, Fructus Foeniculi, 50 grams of Herba Salviae Chinensiss, 30 grams of Herba Selaginellae Doederleiniis, thousand 60 grams of Cutis Bufonis, 30 grams of Herba Sarcandraes, 20 grams of Herba Duchesneae Indicaes, 15 grams of Ganodermas, 30 grams of Radix Gentianaes, 20 grams of field thistles, 30 grams of Radix Arnebiae (Radix Lithospermi)s, 50 grams of Fructus Akebiaes, 30 grams of Hirudos, 15 grams of Herba Artemisiae Scopariaes, 30 grams of Pericarpium Citri Reticulataes, 20 grams of Pheretimas, 300 grams of Scolopendras, 100 grams of Scorpios, 400 grams of Zaocyss, 20 grams of Herba Galii Teneri, 25 grams of Radix Adenophoraes, 30 grams of Radix Glehniaes, 20 grams of Radix Ophiopogonis, 30 grams of Fructus Schisandrae Chinensis, 50 grams of Nidus Vespaes, 20 grams of Periostracum Serpentiss, 20 grams, Flos Sophorae, 15 grams of Gypsum Fibrosum, 15 grams of GUANGXIANG, 19 grams of Fructus Camptothecae Acuminatae, 20 grams of Flos Inulae, 20 grams of Rhizoma Phragmitis, 30 grams of Herba Schizonepetae, 20 grams of Fructus Arctiis, 15 grams of Rhizoma Polygonati Odorati, 20 grams of Lasiosphaera Seu Calvatia, 15 grams of Boraxs, , 20 grams of Fructus Mumes, 10 grams of Haematitums, 50 grams of Catharsii molossis, 20 grams of Fructus Forsythiaes, 30 grams of Flos Magnoliaes, 30 grams of Radix Isatidis, 20 grams of Rhizoma Et Radix Notopterygiis, 30 grams of Herba Houttuyniae, 20 grams of the Fructus Kochiae, 30 grams of Radix Scutellariaes, 20 grams of Herba Centipedae, 50 grams of Rhizoma Dioscoreae Nipponicae, 20 grams, Radix Glycyrrhizae, 15 grams of Indigo Naturaliss, 500 grams of Borneolum Syntheticums, 20 grams of Semen Cuscutae, 30 grams of Radix Saposhnikoviaes, 30 grams of Rhizoma Homalomenaes, 20 grams of Cortex Lycii, 20 grams of Radix Dipsacis, 30 grams of Radix Aconiti Preparatas, 30 grams of Radix Cyathulaes, 20 grams of Radix Angelicae Pubescentiss, 20 grams of Rhizoma Alismatis, 50 grams of Herba speranskiae tuberculataes, 30 grams of Semen Strychni, 20 grams of Caulis Spatholobis, 30 grams of Radix Cynanchi Paniculatis, 15 grams of Rhizoma Sparganii, 20 grams of Cortex erythrinaes, 2000 grams of Gallus Domesticuss, 20 grams of Ramulus Cinnamomi, 15 grams, Herba Ephedrae, 30 grams of Flos Daturae, 50 grams of Geckos, 20 grams of Folium Isatidiss, 5 kilograms, Oleum Sesami, 2 kilograms of Plumbum preparatium, 50 grams, Moschus.
Preparation method is as follows:
(1) prepare A preparation: get each component of A preparation, pulverize, mix, add water to submerge, soak 24 hours, decoct with water 3 hours, filter, obtain medicine juice, be A preparation, standby.
(2) prepare B preparation: get each crude drug except Oleum Sesami, Plumbum preparatium in B preparation, pulverize, mix, add Oleum Sesami submergence, soak 48 hours, be then fried, after medicine is withered and yellow, pull medicinal residues out, obtain medicine oil, be B preparation, standby.
(3) the cancer preparation of plaster that relieves the pain: above-mentioned B preparation is added in A preparation, decoct 5 hours, lower Plumbum preparatium, stir into mastic, then add cold water (10 ℃ of temperature) to soak releasing fire-toxin, within one day, change water once, soak after 7 days, obtain plaster, during use, plaster is coated on cotton or plaster paster.
During treatment, in conjunction with patient's disease, aim at affected area, symmetrical each in front and back one forced on, 7 days courses for the treatment of (efficacy of a drug effect duration of forcing on is about 7 days).Add soak winter and get final product (while having a bath, peel, wash again and stick).General patient with advanced cancer, on plaster after, patient can have the sensation that slows down pain during 8 hours to 24 hours.The plaster efficacy of a drug of the present invention is unique lastingly, auxiliary without other antalgicas.The analgesic effect of plaster of the present invention, is not only embodied in and alleviates patient's pain, improves patient's mental attitude, extends the aspects such as patient's life-span, also can bring many convenience and spiritual comfort to patients' relatives.
Clinical data
Patient's data: the cancer of the present invention plaster that relieves the pain, there are treatment patient 105 examples of statistics, be cancer middle and advanced stage patient, wherein, male 63 examples, female's 42 examples, 47～85 years old age.Hepatocarcinoma 29 examples, 27 cases of lung cancer, uterus carcinoma 9 examples, cancer of pancreas 8 examples, bladder cancer 7 examples, gastric cancer 13 examples, the esophageal carcinoma 7 examples, colorectal cancer 5 examples.
II phases 19 clinical stages example, III phases 26 example, IV phases 60 example; Press the comprehensive NRS methods of marking of WHO pain criterion of therapeutical effect Pain Grading: I level 49 examples, II level 28 examples, III level 15 examples, IV level 13 examples.
Inclusive criteria: all selected patients through pathology or cytology, make a definite diagnosis in, patients with advanced malignant tumor, and with in, severe pain, need Drug therapy person; Get rid of other Non-cancerous pain factors; Language competence is normal, and self pain and general status are had to judgement, and can cooperation evaluate pain and quality of life content etc.; Estimate >1 month life cycle; Kamofskv scoring >60 divides; Enter in the front 4h of group and do not use analgesic or tranquilizer, in 12h, do not use sustained-release analgesic; The heart, liver, renal function are without serious hindrance; Without drug dependence history; Experimenter fully understand participate in test benefit and risk, be voluntarily, treatment coordinates.
Exclusion standard: the person that do not meet inclusive criteria; With respiration inhibition, respiratory tract obstruction, anoxia, high hot person; There are the obvious heart, brain, liver, renal dysfunction person, or have hemorrhage and obvious bleeding tendency person; To drug allergy person; Traitor is pregnent, women breast-feeding their children; Extreme exhaustion's state, estimates life cycle and is less than 1 month person; There is drug dependence history person; With spirit, disturbance of consciousness, can not cooperation estimator.
Therapeutic modality: the cancer that patient all pastes embodiment 1 plaster (sticking on affected part, 7 days courses for the treatment of) that relieves the pain, after two weeks (2 courses for the treatment of), statistics curative effect.
Pain therapeutic evaluation: press 4 grades of criteria for classifications of WHO in conjunction with NRS point system.From 0 to 10 totally 11 numerals, represent from painless to having an intense pain most, by patient oneself, iris out 1 numeral, show its pain degree.Wherein 0 grade of expression is painless; 1～3 grade of mild pain, pain is slight, can orthobiosis, do not affect sleep; 4～6 grades of moderate pains, show as lasting severe pain, sleep be disturbed, need analgesics; 7～9 grades of severe pain, strong persistence severe pain, can seriously be disturbed with compulsive position and autonomic nervous dysfunction, sleep.Pain intensity * 100 before pain relief percent=(the rear pain intensity of pain intensity-treatment before treatment)/treatment.Alleviate completely: after treatment, pain reduces 91%～100%; Partial rcsponse: after treatment, pain reduces 61%～90.9%; Slight alleviation: after treatment, pain reduces 21.0%～60.9%; Invalid: after treatment, pain reduces <20.9%.
Therapeutic outcome:
I level 49 examples, alleviate 49 examples completely, effective percentage 100%.
II level 28 examples, alleviate 7 examples completely, and partial rcsponse 9 examples, slightly alleviate 8 examples, invalid 4 examples, total effective rate 85.7%.
III level 15 examples, alleviate 5 examples completely, and partial rcsponse 4 examples, slightly alleviate 3 examples, invalid 3 examples, total effective rate 80%.
IV level 13 examples, alleviate 0 example completely, and partial rcsponse 3 examples, slightly alleviate 6 examples, invalid 4 examples, total effective rate 69.2%.
Clinical case
Case 1: Hengshui, Hebei king so-and-so, man, 63 years old, 2011 at certain hospital admission, was diagnosed as and suffered from advanced liver cancer, while leaving hospital, hospital diagnosis also has at most the vital stages of four months.Hurt like hell after leaving hospital, diet seldom.Stick cancer of the present invention and relieve the pain plaster after one day, mental attitude has obtained obvious improvement, and pain has had obvious alleviation, and diet is normal, and life can be taken care of oneself.Patient adheres to pasting the cancer of the present invention plaster that relieves the pain, until leave hospital, within latter nine months, dies of illness, and with comparing for four months of hospital diagnosis, has extended 5 months.After patient dies of illness, family numbers of patients sincerity is thanked the present inventor, thank cancer of the present invention to relieve the pain effect that plaster brings.
Case 2: Nanjing Wang, female, 57 years old, suffer from uterus carcinoma, in late period, pain, needs within one day, to buy 10, morphine, but still cannot stop pain, the rolling in bed of patient's pain.Paste cancer of the present invention and relieve the pain plaster after three days, obviously stopped pain, without playing morphine pin, the health that has alleviated patient is painful, has alleviated the psychic pain of patients' relatives, and patient in person writes letter and thanks to the present inventor.
Case 3: Beijing Jiang, man, 71 years old, advanced lung cancer, and there is diffusion transfer, and whole body many places pain, often household being got angry of pain, cannot fall asleep.Note cancer of the present invention relieved the pain plaster after six hours, and pain has obtained slowing down, and tranquil mood, no longer gets angry to household, can fall asleep, and rule of life is normal.
Case 4: Jinan Zhang, female, suffers from cancer of pancreas, after hospital has an operation, has occurred diffusion, hurt like hell, oral pain alleviating Chinese herbal medicine and beat pain killer injection and all cannot prevent pain, family numbers of patients is at one's wit's end.Adopt plaster of the present invention after one day, pain has obtained alleviation greatly, never again oral analgesic and beat pain killer injection.At last four months of patient's life, paste the cancer of the present invention plaster that relieves the pain always, there is never again situation about having an intense pain, patient is able to peacefully dead.
Case 5: Xi'an Zhao, man, 57 years old, suffer from bladder cancer, diffusion transfer in late period, gnawing pains take no rest, adopts the multiple method that relieves the pain, and effect is all not obvious.At affected area, paste the cancer of the present invention plaster that relieves the pain, after three days, pain has obtained obvious alleviation.At pain in patients with metastatic position, also correspondingly paste the cancer of the present invention plaster that relieves the pain, pain has obtained obvious alleviation, occurs never again the sight that has an intense pain, until after five months, patient's euthanasia.
Case 6: the king of Langfang in Hebei Province so-and-so, 70 years old, suffer from gastric cancer, have an operation after cut-out and occurred again lump tumor, gnawing pains take no rest, pastes the cancer of the present invention plaster that relieves the pain, after two months, analgesic effect is obvious, dwindling and softening, have appearred in tumor stomach film making, and patient's diet, sleep recover normal, paste the cancer of the present invention plaster that relieves the pain, until dead after six months always.
Claims (2)
1. the cancer plaster that relieves the pain, is characterized in that: by A preparation and B preparation, made, wherein, A preparation is made by following component:
Five: Ramulus Persicae, Ramulus Salicis Babylonicae, Ramulus sophorae, Ramulus ulmi pumilae, Ramulus Mori, each 15～25 grams, preferred, each 20 grams;
Five skins: Cortex Pini, Cortex Jujubae, tangerine skin, bark of Toona sinensis, Cortex Juglandis, each 25～35 grams, preferred, each 30 grams;
One brick: 1000 ± 50 grams of blue bricks;
One stone: 2000 ± 50 grams of limestone;
Five cores: almond, Semen Persicae, Semen Jujubae, Semen Litchi, Fructus Citri tangerinae core, each 50 ± 3 grams;
Described B preparation is made by following crude drug:
15 ± 2 grams, Poria, 20 ± 2 grams of the Rhizoma Pinelliaes, 18 ± 2 grams of Rhizoma Arisaematis, 15 ± 2 grams of Fructus Trichosanthis, 20 ± 2 grams, Rhizoma Gastrodiae, 12 ± 2 grams of Semen Coiciss, 10 ± 2 grams of Squama Manis, 25 ± 2 grams of the Radixs Angelicae Dahuricae, 30 ± 2 grams of Herba Scutellariae Barbataes, 20 ± 2 grams of Radix Angelicae Sinensis, 30 ± 2 grams of Rhizoma Chuanxiongs, 15 ± 2 grams of Radix Paeoniae Rubra, 20 ± 2 grams, the Radix Rehmanniae, 10 ± 2 grams, Semen Persicae, 20 ± 2 grams, Flos Carthami, 15 ± 2 grams of Rhizoma Curcumae, 50 ± 2 grams of Eupolyphaga Seu Steleophagas, 20 ± 2 grams of Pheretimas, 20 ± 2 grams of Bombyx Batryticatus, 30 ± 2 grams of Fructus Xanthii, 15 ± 2 grams of Rhizoma Dioscoreae Bulbiferaes, 10 ± 2 grams of Thallus Laminariae (Thallus Eckloniae)s, 25 ± 2 grams, Radix Rehmanniae Preparata, 30 ± 2 grams of Rhizoma Dioscoreaes, 15 ± 2 grams of Fructus Corni, 15 ± 2 grams of Cortex Cinnamomis, 20 ± 2 grams of Rhizoma Zingiberis Preparatums, 25 ± 2 grams of Fructus Lyciis, 20 ± 2 grams of Colla cornus cervis, 20 ± 2 grams of Colla Plastri Testudinis, 50 ± 2 grams of Herba Epimedii, 20 ± 2 grams of Radix Aconiti Lateralis Preparata, 30 ± 2 grams of Radix Rumiciss, 15 ± 2 grams of Polyporus, 15 ± 2 grams of Pseudobulbus Cremastrae Seu Pleioness, 20 ± 2 grams of Radix Asparagis, 30 ± 2 grams of Radix Sophorae Tonkinensiss, 80 ± 2 grams of the Radixs Astragali, 30 ± 2 grams of the Rhizoma Atractylodis Macrocephalaes, 20 ± 2 grams of Rhizoma Imperataes, 25 ± 2 grams of the Rhizoma Anemarrhenaes, 20 ± 2 grams of Radix Scrophulariaes, 30 ± 2 grams of Concha Ostreaes, 20 ± 2 grams of Spica Prunellaes, 100 ± 2 grams of Rhizoma Paridis, 30 ± 2 grams of Hedyotidis Diffusaes, 30 ± 2 grams of Radix Et Caulis Acanthopanacis Senticosis, 50 ± 2 grams, Fructus Jujubae, 20 ± 2 grams of Fructus Ligustri Lucidi, 15 ± 2 grams of Herba Taxillis, 30 ± 2 grams of Rhizoma Coptidis, 20 ± 2 grams of Radix Salviae Miltiorrhizaes, 30 ± 2 grams of Cortex Moutans, 30 ± 2 grams of Flos Loniceraes, 50 ± 2 grams of Rhizoma Polygoni Cuspidati, 20 ± 2 grams of Radix Gentianaes, 30 ± 2 grams of Radix Bupleuri, 50 ± 2 grams of Herba Leonuris, 20 ± 2 grams of Herba Scutellariae Barbataes, 30 ± 2 grams of Rhizoma Corydalis, 25 ± 2 grams of Oletum Trogopteroris, 30 ± 2 grams of Radix Platycodoniss, 20 ± 2 grams of Fructus Aurantii Immaturuss, 30 ± 2 grams of Olibanums, 50 ± 2 grams of Myrrhas, 150 ± 2 grams of Aspongopuss, 15 ± 2 grams of Radixs Stephaniae Tetrandrae, 20 ± 2 grams of Herba Solani Nigris, 30 ± 2 grams of Herba Patriniae, 20 ± 2 grams of Radix Curcumaes, 30 ± 2 grams of Aloes, 20 ± 2 grams of Radix Codonopsis, 30 ± 2 grams of Rhizoma Cimicifugaes, 20 ± 2 grams of Cortex Phellodendris, 30 ± 2 grams of Rhizoma Atractylodis, 15 ± 2 grams of Fructus Gardeniaes, 30 ± 2 grams of Herba Solani Lyratis, 30 ± 2 grams of Ramulus Euonymis, 50 ± 2 grams of Folium cordylines fruticosaes, 30 ± 2 grams of Herba Violaes, 30 ± 2 grams of Herba Taraxacis, 50 ± 2 grams of Radix Notoginseng, 100 ± 2 grams of Semen Vaccariae, 15 ± 2 grams of ghost thorns, 30 ± 2 grams of Herba Cistanches, 30 ± 2 grams, Fructus Foeniculi, 50 ± 2 grams of Herba Salviae Chinensiss, 30 ± 2 grams of Herba Selaginellae Doederleiniis, thousand 60 ± 2 grams of Cutis Bufonis, 30 ± 2 grams of Herba Sarcandraes, 20 ± 2 grams of Herba Duchesneae Indicaes, 15 ± 2 grams of Ganodermas, 30 ± 2 grams of Radix Gentianaes, 20 ± 2 grams of field thistles, 30 ± 2 grams of Radix Arnebiae (Radix Lithospermi)s, 50 ± 2 grams of Fructus Akebiaes, 30 ± 2 grams of Hirudos, 15 ± 2 grams of Herba Artemisiae Scopariaes, 30 ± 2 grams of Pericarpium Citri Reticulataes, 20 ± 2 grams of Pheretimas, 300 ± 10 grams of Scolopendras, 100 ± 2 grams of Scorpios, 400 ± 20 grams of Zaocyss, 20 ± 2 grams of Herba Galii Teneri, 25 ± 2 grams of Radix Adenophoraes, 30 ± 2 grams of Radix Glehniaes, 20 ± 2 grams of Radix Ophiopogonis, 30 ± 2 grams of Fructus Schisandrae Chinensis, 50 ± 2 grams of Nidus Vespaes, 20 ± 2 grams of Periostracum Serpentiss, 20 ± 2 grams, Flos Sophorae, 15 ± 2 grams of Gypsum Fibrosum, 15 ± 2 grams of GUANGXIANG, 19 ± 2 grams of Fructus Camptothecae Acuminatae, 20 ± 2 grams of Flos Inulae, 20 ± 2 grams of Rhizoma Phragmitis, 30 ± 2 grams of Herba Schizonepetae, 20 ± 2 grams of Fructus Arctiis, 15 ± 2 grams of Rhizoma Polygonati Odorati, 20 ± 2 grams of Lasiosphaera Seu Calvatia, 15 ± 2 grams of Boraxs, , 20 ± 2 grams of Fructus Mumes, 10 ± 2 grams of Haematitums, 50 ± 2 grams of Catharsii molossis, 20 ± 2 grams of Fructus Forsythiaes, 30 ± 2 grams of Flos Magnoliaes, 30 ± 2 grams of Radix Isatidis, 20 ± 2 grams of Rhizoma Et Radix Notopterygiis, 30 ± 2 grams of Herba Houttuyniae, 20 ± 2 grams of the Fructus Kochiae, 30 ± 2 grams of Radix Scutellariaes, 20 ± 2 grams of Herba Centipedae, 50 ± 2 grams of Rhizoma Dioscoreae Nipponicae, 20 ± 2 grams, Radix Glycyrrhizae, 15 ± 2 grams of Indigo Naturaliss, 500 ± 2 grams of Borneolum Syntheticums, 20 ± 2 grams of Semen Cuscutae, 30 ± 2 grams of Radix Saposhnikoviaes, 30 ± 2 grams of Rhizoma Homalomenaes, 20 ± 2 grams of Cortex Lycii, 20 ± 2 grams of Radix Dipsacis, 30 ± 2 grams of Radix Aconiti Preparatas, 30 ± 2 grams of Radix Cyathulaes, 20 ± 2 grams of Radix Angelicae Pubescentiss, 20 ± 2 grams of Rhizoma Alismatis, 50 ± 2 grams of Herba speranskiae tuberculataes, 30 ± 2 grams of Semen Strychni, 20 ± 2 grams of Caulis Spatholobis, 30 ± 2 grams of Radix Cynanchi Paniculatis, 15 ± 2 grams of Rhizoma Sparganii, 20 ± 2 grams of Cortex erythrinaes, 2000 ± 2 grams of Gallus Domesticuss, 20 ± 2 grams of Ramulus Cinnamomi, 15 ± 2 grams, Herba Ephedrae, 30 ± 2 grams of Flos Daturae, 50 ± 2 grams of Geckos, 20 ± 2 grams of Folium Isatidiss, 5 ± 0.5 kilograms, Oleum Sesami, 2 ± 0.5 kilograms of Plumbum preparatium, 50 ± 2 grams, Moschus.
2. the cancer claimed in claim 1 preparation method of plaster that relieves the pain, is characterized in that: step is as follows:
(1) preparation of A preparation: get each component, pulverize, mix, add water to submerge, soak 20～25 hours, decoct with water 2.5～3.5 hours, filter, obtain medicine juice, be A preparation, standby;
(2) preparation of B preparation: get each crude drug except Oleum Sesami, Plumbum preparatium, pulverize, mix, add Oleum Sesami submergence, soak 45～50 hours, be then fried, after medicine is withered and yellow, pull medicinal residues out, obtain medicine oil, be B preparation, standby;
(3) the cancer preparation of plaster that relieves the pain: above-mentioned B preparation is added in A preparation, decoct 4.5～5.5 hours, lower Plumbum preparatium, stirs into mastic, then adds cold water (4～20 ℃ of temperature) to soak releasing fire-toxin, within one day, changes water once, soaks after 7 days, obtains plaster.
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