CN105833016A

CN105833016A - Traditional Chinese medicine composition for treating ovarian cancer

Info

Publication number: CN105833016A
Application number: CN201610365040.5A
Authority: CN
Inventors: 宋羽
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-05-26
Filing date: 2016-05-26
Publication date: 2016-08-10

Abstract

The invention discloses a traditional Chinese medicine composition for treating ovarian cancer. The traditional Chinese medicine composition is prepared by, by weight, 0.3-0.9 part of radix acanthopanacis senticosi, 3.6-5.8 parts of brucea javanica, 0.6-2.8 parts of radix ginseng rubra, 5.0-8.3 parts of radix astragali, 2.1-3.5 parts of myrrh, 6.3-9.0 parts of radix lithospermi, 0.5-2.8 parts of ganoderma lucidum, 0.4-3 parts of panax notoginseng, 2.1-5.6 parts of ramulus cinnamomi, 0.2-2.3 parts of agrimonia pilosa ledeb, 40-50 parts of Smilax nipponica Miq., 15-25 parts of Veronica peregrina L., 10-20 parts of Schisandra glaucescens Diels., 5-8 parts of semen cuscutae, 9-13 parts of folium ginkgo and 3.0-9.6 parts of Scrophulariaceae Striga masuria. The traditional Chinese medicine composition has beneficial effects of strengthening the body resistance and consolidating the basis, invigorating qi to nourish the blood, promoting blood circulation to remove blood stasis, clearing away heat and toxic materials and resisting cancer and is evident in effect, quick in action and capable of resisting the ovarian cancer by coordinating with other treatment manners.

Description

A kind of Chinese medicine composition treating ovarian cancer

Technical field

The invention belongs to treat the field of Chinese medicines of tumor.

Background technology

Malignant tumor of ovary is one of common malignant tumor of female sex organ, and sickness rate is only second to cervical cancer With carcinoma of uterine body and arrange residence the 3rd.But ovarian epithelium mortality of carcinoma accounts for the first place of all kinds of gynecological tumor, to woman Schoolgirl's life causes serious threat.Now it is intended to treat the Chinese medicine aspect of ovarian tumor, there are some the most not Foot: one is that therapeutic effect is the most obvious；Two is that the comparison that takes effect is slow.To such an extent as to many ovarian cancer patients or Recurring after can not effectively suppressing tumor growth, or excision, patient and family members thereof are not satisfied to this.

For posed problems above, the present invention provides a kind of Chinese medicine treating ovarian cancer, and it can solve the problem that in the past In treatment of ovarian cancer, effect is obvious not, and the problem that the comparison that takes effect is slow is effective, instant effect, has effect Significantly, the advantage of quick result.

Summary of the invention

Present invention aim to address the problem proposed in background technology.

In order to reach object above, the technical solution used in the present invention is as follows:

A kind of Chinese medicine composition treating ovarian cancer, is characterized in that: it is to make with the component of following weight ratio , its component proportioning is:

Radix Et Caulis Acanthopanacis Senticosi 0.3-0.9 part, Fructus Bruceae 3.6-5.8 part, Radix Ginseng Rubra 0.6-2.8 part, Radix Astragali 5.0-8.3 Part, Myrrha 2.1-3.5 part, Radix Arnebiae (Radix Lithospermi) 6.3-9.0 part, Ganoderma 0.5-2.8 part, Radix Notoginseng 0.4-3 part, Ramulus Cinnamomi 2.1-5.6 part, Herba Agrimoniae 0.2-2.3 part, Rhizoma Smilacis nipponicae 40-50 part, Herba Veronicae peregrinae 15-25 part, flower blood Rattan 10-20 part, Semen Cuscutae 5-8 part, Folium Ginkgo 9-13 part；Big Herba Lobeliae Chinensis 3.0-9.6 part, Fructus Broussonetiae 30-40 Part, fruit 10-16 part, Herba Silybi mariani fly Ji 0.8-7.6 part, Rhizoma Polygonati Cirrhifolii 17-35 part, Cornu Cervi Degelatinatum 4-15 Part, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 2-9 part, Radix Rhodiolae Yunnanensis 5-15 part, Herba Sedi 25-30 part, grand calyx angelica root 10-20 part, Rhizoma Atractylodis Macrocephalae 4-15 part, Fructus Akebiae 3.2-6.8 part, Radix Aucklandiae 5.6-12 part, Radix Rehmanniae 9-12 part, Fructus Arctii 10-19 Part, Fructus Forsythiae 15-33 part.

The present invention compared with prior art, provides the benefit that: can solve the problem that effect during conventional treatment of ovarian cancer Obvious not, the problem that the comparison that takes effect is slow, it is accordingly required in particular to it is noted that through practical proof many times, Only when Radix Et Caulis Acanthopanacis Senticosi, Fructus Bruceae, the proportioning of Schisandra glaucescens Diels. are 0.3-0.9:3.6-5.8:10-20 when, association Best with synergistic effect, the Chinese medicine composition of this treatment ovarian cancer is notable to treatment ovarian cancer effect, takes effect relatively Hurry up.

Detailed description of the invention

The following is the specific embodiment of the present invention, technical scheme is described further, but Embodiments of the present invention are not limited to these embodiments.

Embodiment 1, take formula as below (by weight):

Radix Et Caulis Acanthopanacis Senticosi 0.6 part, Fructus Bruceae 4.3 parts, Radix Ginseng Rubra 2.0 parts, the Radix Astragali 6.3 parts, Myrrha 2.8 Part, Radix Arnebiae (Radix Lithospermi) 7.5 parts, Ganoderma 1.5 parts, Radix Notoginseng 2 parts, Ramulus Cinnamomi 2.9 parts, Herba Agrimoniae 1.8 parts, Rhizoma Smilacis nipponicae 45 parts, Herba Veronicae peregrinae 20 parts, Schisandra glaucescens Diels. 15 parts, Semen Cuscutae 6 parts, Folium Ginkgo 10 parts, big Herba Lobeliae Chinensis 5.8 parts, Fructus Broussonetiae 33 parts, fruit 12 parts, Herba Silybi mariani 4.9 parts, old Tiger Rhizoma Zingiberis Recens 22 parts, Cornu Cervi Degelatinatum 12 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 7.5 parts, Radix Rhodiolae Yunnanensis 11 parts, Herba Sedi 26 parts, grand Calyx angelica root 18 parts, the Rhizoma Atractylodis Macrocephalae 9 parts, Fructus Akebiae 5.0 parts, the Radix Aucklandiae 8 parts, 10 parts of the Radix Rehmanniae, Fructus Arctii 17 parts, Fructus Forsythiae 22 parts.

(1) by above-mentioned weight ratio, Radix Et Caulis Acanthopanacis Senticosi, Fructus Bruceae, Ganoderma, Radix Notoginseng, Ramulus Cinnamomi, Herba Agrimoniae part, horse hair are stretched Muscle, Herba Veronicae peregrinae, Schisandra glaucescens Diels., Fructus Broussonetiae, fruit, Herba Silybi mariani, Rhizoma Polygonati Cirrhifolii, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., Radix Rhodiolae Yunnanensis, Herba Sedi, Fructus Akebiae, the Radix Aucklandiae, clean roguing, dry, be ground into granule；

(2) take above-mentioned granule and add 3-8 times amount 42%-75% alcohol reflux 2-5 time, 1.0-2.5h/ time, Alcohol extract；

(3) by above-mentioned weight ratio, by Radix Ginseng Rubra, the Radix Astragali, Myrrha, Radix Arnebiae (Radix Lithospermi), Semen Cuscutae, Folium Ginkgo, big Herba Lobeliae Chinensis, Cornu Cervi Degelatinatum, grand calyx angelica root, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae, Fructus Arctii, Fructus Forsythiae are ground into fine powder respectively, with above-mentioned alcohol extract It is sufficiently mixed, stirs, obtain medicine liquid mixture；

(4) above-mentioned medicine liquid mixture is added 1.5-2 times of water, soak 2-2.5h, be placed in multi-functional extraction in filling and decoct 2 times: add up the water of medical material 4-6 times amount for the first time, decocting 2h, take decocting liquid, filter, second time adds up medicine The water of 8-10 times amount, decocts 2.5h, takes twice decocting liquid and merges, filters, and when being concentrated into 90 DEG C, relative density is The concentrated solution of 1.38, sets to 0 concentrated solution-5 DEG C of deepfreeze 48h, obtains semi-finished product；

(5) again by the 4th step obtain described semi-finished product carry out successively filtration treatment, concentration, embedding process, Sterilization treatment, obtains every milliliter of Chinese medicine composition oral liquid finished product containing 2.5g crude drug amount.

Embodiment 2, take formula as below (by weight):

Radix Et Caulis Acanthopanacis Senticosi 0.4 part, Fructus Bruceae 3.8 parts, Radix Ginseng Rubra 1.0 parts, the Radix Astragali 5.3 parts, Myrrha 2.8 parts, Radix Arnebiae (Radix Lithospermi) 6.5 parts, Ganoderma 0.8 part, Radix Notoginseng 0.5 part, Ramulus Cinnamomi 2.3 parts, Herba Agrimoniae 0.5 part, horse Tail stretch 41 parts of muscle, Herba Veronicae peregrinae 16 parts, Schisandra glaucescens Diels. 11 parts, Semen Cuscutae 5.5 parts, Folium Ginkgo 10 parts, Big Herba Lobeliae Chinensis 3.3 parts, Fructus Broussonetiae 32 parts, fruit 12 parts, Herba Silybi mariani 0.9 part, Rhizoma Polygonati Cirrhifolii 18 Part, Cornu Cervi Degelatinatum 6 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 2.5 parts, Radix Rhodiolae Yunnanensis 6.3 parts, Herba Sedi 26 parts, grand calyx Radix Angelicae Sinensis Root 13 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Fructus Akebiae 3.6 parts, the Radix Aucklandiae 5.8 parts, 10.5 parts of the Radix Rehmanniae, Fructus Arctii 12 Part, Fructus Forsythiae 17 parts.

By above-mentioned same method, make every milliliter of crude drug amount Chinese medicine composition oral liquid Han 2.5g.

Embodiment 3, take formula as below (by weight):

Radix Et Caulis Acanthopanacis Senticosi 0.8 part, Fructus Bruceae 5.6 parts, Radix Ginseng Rubra 2.5 parts, the Radix Astragali 8.1 parts, Myrrha 3.3 Part, Radix Arnebiae (Radix Lithospermi) 8 parts, Ganoderma 2.5 parts, Radix Notoginseng 2.8 parts, Ramulus Cinnamomi 5.3 parts, Herba Agrimoniae 2.2 parts, Rhizoma Smilacis nipponicae 49 parts, Herba Veronicae peregrinae 24 parts, Schisandra glaucescens Diels. 19 parts, Semen Cuscutae 7 parts, Folium Ginkgo 12 parts, Big Herba Lobeliae Chinensis 9.3 parts, Fructus Broussonetiae 38.5 parts, fruit 10-16 part, Herba Silybi mariani 7.3 parts, tiger Rhizoma Zingiberis Recens 32 parts, Cornu Cervi Degelatinatum 13 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 8 parts, Radix Rhodiolae Yunnanensis 14 parts, Herba Sedi 25-30 part, grand Calyx angelica root 19 parts, the Rhizoma Atractylodis Macrocephalae 13.8 parts, Fructus Akebiae 6.3 parts, the Radix Aucklandiae 11.3 parts, 10.9 parts of the Radix Rehmanniae, Fructus Arctii 18 parts, Fructus Forsythiae 31.8 parts.

Embodiment 4:

Take formula as below (by weight):

Radix Et Caulis Acanthopanacis Senticosi 1.2 parts, Fructus Bruceae 2.6 parts, Radix Ginseng Rubra 2.5 parts, the Radix Astragali 8.1 parts, Myrrha 3.3 Part, Radix Arnebiae (Radix Lithospermi) 8 parts, Ganoderma 2.5 parts, Radix Notoginseng 2.8 parts, Ramulus Cinnamomi 5.3 parts, Herba Agrimoniae 2.2 parts, Rhizoma Smilacis nipponicae 49 parts, Herba Veronicae peregrinae 24 parts, Schisandra glaucescens Diels. 8 parts, Semen Cuscutae 7 parts, Folium Ginkgo 12 parts, Big Herba Lobeliae Chinensis 9.3 parts, Fructus Broussonetiae 38.5 parts, fruit 10-16 part, Herba Silybi mariani 7.3 parts, tiger Rhizoma Zingiberis Recens 32 parts, Cornu Cervi Degelatinatum 13 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 8 parts, Radix Rhodiolae Yunnanensis 14 parts, Herba Sedi 25-30 part, grand Calyx angelica root 19 parts, the Rhizoma Atractylodis Macrocephalae 13.8 parts, Fructus Akebiae 6.3 parts, the Radix Aucklandiae 11.3 parts, 10.9 parts of the Radix Rehmanniae, Fructus Arctii 18 parts, Fructus Forsythiae 31.8 parts.

Illustrate: Radix Et Caulis Acanthopanacis Senticosi, Fructus Bruceae, Schisandra glaucescens Diels. proportioning not within the scope of described in claims.

Embodiment 5:

Take formula as below (by weight):

Radix Et Caulis Acanthopanacis Senticosi 0.1 part, Fructus Bruceae 8 parts, Radix Ginseng Rubra 2.5 parts, the Radix Astragali 8.1 parts, Myrrha 3.3 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Ganoderma 2.5 parts, Radix Notoginseng 2.8 parts, Ramulus Cinnamomi 5.3 parts, Herba Agrimoniae 2.2 parts, horse Tail stretches 49 parts of muscle, Herba Veronicae peregrinae 24 parts, Schisandra glaucescens Diels. 3 parts, Semen Cuscutae 7 parts, Folium Ginkgo 12 parts, big Herba Lobeliae Chinensis 9.3 parts, Fructus Broussonetiae 38.5 parts, fruit 10-16 part, Herba Silybi mariani 7.3 parts, Rhizoma Polygonati Cirrhifolii 32 parts, Cornu Cervi Degelatinatum 13 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 8 parts, Radix Rhodiolae Yunnanensis 14 parts, Herba Sedi 25-30 part, grand calyx Angelica root 19 parts, the Rhizoma Atractylodis Macrocephalae 13.8 parts, Fructus Akebiae 6.3 parts, the Radix Aucklandiae 11.3 parts, 10.9 parts of the Radix Rehmanniae, Fructus Arctii 18 parts, Fructus Forsythiae 31.8 parts.

Clinical data:

The present invention is as a example by traditional Chinese medical science ovarian cancer, through 50 example clinical observations.Select tcm diagnosis ovarian cancer for mark Accurate: limb is soft weak, lower abdominal distention pain, and CT is shown in ovary region tumors.As above symptom, can make a definite diagnosis.? Making a definite diagnosis the object of observation, without other serious disease, the age is 31 years old-62 years old, 52.6 years old mean age. Efficacy determination:

1, effective: body constitution strengthens, limbs are strong, and abdominal discomfort disappears, and ovarian tumor tumor body reduces, other portion Position has no nascent tumor.

2, effective: body constitution strengthens, and ovarian tumor has no increase, and other position has no nascent tumor.

3, invalid: symptom is unchanged, ovarian tumor tumor body increases, or nascent tumor occurs in other position.

During clinical experiment, withdraw other medicines and health nutrient.Take Chinese medicine oral liquid of the present invention, observe 3 Individual month, be a course for the treatment of.Instructions of taking: three times a day, each 10ml, one after each meal, after 1 month Symptom i.e. has alleviation, and after taking 3 months, symptom has clear improvement.

Take the medicinal liquid of embodiment 1 preparation: in 50 people of clinical experiment, effective 20 people, effective 29 people, Invalid 1 people, total effective rate 98.0%.

Take the medicinal liquid of embodiment 2 preparation: in 50 people of clinical experiment, effective 20 people, effective 28 people, Invalid 2 people, total effective rate 96.0%.

Take the medicinal liquid of embodiment 3 preparation: in 50 people of clinical experiment, effective 22 people, effective 27 people, Invalid 1 people, total effective rate 98.0%.

Take the medicinal liquid of embodiment 4 preparation: in 50 people of clinical experiment, effective 2 people, effective 8 people, Invalid 40 people, total effective rate 20.0%.

Take the medicinal liquid of embodiment 5 preparation: in 50 people of clinical experiment, effective 1 people, effective 9 people, Invalid 40 people, total effective rate 20.0%.

Owing to embodiment 4 and embodiment 5 do not install the requirement proportioning preparation of the present invention, experiment effect is very Difference, also illustrate that the medicine of the present invention is only when Radix Et Caulis Acanthopanacis Senticosi, Fructus Bruceae, the joining of Schisandra glaucescens Diels. to a certain extent Than for the when of 0.3-0.9:3.6-5.8:10-20, cooperative synergism effect is just most preferably over the course for the treatment of.

Claims

1. treat a Chinese medicine composition for ovarian cancer, it is characterized in that: it is to make with the component of following weight ratio , its component proportioning is:

Radix Et Caulis Acanthopanacis Senticosi 0.3-0.9 part, Fructus Bruceae 3.6-5.8 part, Radix Ginseng Rubra 0.6-2.8 part, Radix Astragali 5.0-8.3 Part, Myrrha 2.1-3.5 part, Radix Arnebiae (Radix Lithospermi) 6.3-9.0 part, Ganoderma 0.5-2.8 part, Radix Notoginseng 0.4-3 part, Ramulus Cinnamomi 2.1-5.6 part, Herba Agrimoniae 0.2-2.3 part, Rhizoma Smilacis nipponicae 40-50 part, Herba Veronicae peregrinae 15-25 part, flower blood Rattan 10-20 part, Semen Cuscutae 5-8 part, Folium Ginkgo 9-13 part；Big Herba Lobeliae Chinensis 3.0-9.6 part, Fructus Broussonetiae 30-40 Part, fruit 10-16 part, Herba Silybi mariani 0.8-7.6 part, Rhizoma Polygonati Cirrhifolii 17-35 part, Cornu Cervi Degelatinatum 4-15 part, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 2-9 part, Radix Rhodiolae Yunnanensis 5-15 part, Herba Sedi 25-30 part, grand calyx angelica root 10-20 part, the Rhizoma Atractylodis Macrocephalae 4-15 part, Fructus Akebiae 3.2-6.8 part, Radix Aucklandiae 5.6-12 part, Radix Rehmanniae 9-12 part, Fructus Arctii 10-19 part, Fructus Forsythiae Fructus Forsythiae 15-33 part.