CN103705780A - Medicament for treating intractable insomnia - Google Patents
Medicament for treating intractable insomnia Download PDFInfo
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- CN103705780A CN103705780A CN201410000558.XA CN201410000558A CN103705780A CN 103705780 A CN103705780 A CN 103705780A CN 201410000558 A CN201410000558 A CN 201410000558A CN 103705780 A CN103705780 A CN 103705780A
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Abstract
The invention relates to a medicament for treating intractable insomnia. The medicament is prepared from the following raw material medicines in parts by weight: gomphrena globosa, elatostema oblohgifolium fu., lysimachia barystachys bunge, wheatgrass, oxalis corymbosa, erigeron annuus, salvia roborowskii, ginseng fruits, stellaria yunnanensis, threeleaf loosestrife herb, canna generalis, a Kunmingshan crab apple extract, commelina hengalensis L., Jenkine dendrobium, gymnema yunnanense Tsiang, leaves or fruits of whiteflower tarenna, hydrangea paniculata, salvia chinensis, osbeckia crinita benth.ex wall and herba barleriae lupulinae. The medicament for treating intractable insomnia has the effects of removing heat to cool blood, engendering liquid and nourishing yin and tranquilizing by nourishing the heart, and can effectively treat intractable insomnia.
Description
Technical field
The present invention relates to psychiatric department field, relate in particular to a kind of medicament for the treatment of intractable insomnia.
Background technology
Intractable insomnia is more common clinically a kind of disease, refers to that patient can not obtain a kind of disease of ortho sleep, and the lighter's difficulty falling asleep and easily waking up is difficult to fall asleep after waking up again, and severe one can not be fallen asleep all night, and western modern medicine treatment is a few days ago rather thorny.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of intractable insomnia.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of intractable insomnia, it is to be made by weight by following bulk drugs: Flos Gomphrenae 1-30 part, Elatostema oblohgifolium Fu. (Elatostema bodinier Levl) 1-20 part, XUEJINGCAO 1-20 part, Radix Aneurolepidii 1-20 part, Herba oxalidis corymbosae 1-20 part, Herba Erigerontis Annui 1-20 part, Salvia roborowskii Maxim 1-20 part, Rhizoma Tupistrae Chinensis 1-20 part, Radix Stellariae Yunnanensis 1-20 part, Herba Lysimachiae Insignis 1-20 part, Canna generalis 1-20 part, Herba Begoniae Yunnanensis 1-20 part, horse Auricled Hedyotis Herb 1-20 part, Dendrobium jenkinsii Wall ex Lindl． 1-20 part, Gymnema yunnanense Tsiang 1-20 part, Folium seu Fructus Tarennae 1-20 part, the sub-wooden 1-20 part of water, Herba Salviae Chinensis 1-20 part, look up to heaven clock 1-20 part and thorn blood red 1-20 part.
Preferably, medicament of the present invention is to be made by weight by following bulk drugs: Flos Gomphrenae 1-20 part, Elatostema oblohgifolium Fu. (Elatostema bodinier Levl) 1-15 part, XUEJINGCAO 1-15 part, Radix Aneurolepidii 1-15 part, Herba oxalidis corymbosae 1-15 part, Herba Erigerontis Annui 1-15 part, Salvia roborowskii Maxim 1-15 part, Rhizoma Tupistrae Chinensis 1-15 part, Radix Stellariae Yunnanensis 1-15 part, Herba Lysimachiae Insignis 1-15 part, Canna generalis 1-15 part, Herba Begoniae Yunnanensis 1-10 part, horse Auricled Hedyotis Herb 1-10 part, Dendrobium jenkinsii Wall ex Lindl． 1-10 part, Gymnema yunnanense Tsiang 1-10 part, Folium seu Fructus Tarennae 1-10 part, water sub-wooden 1-10 part, Herba Salviae Chinensis 1-10 part, the clock 1-10 part and sting blood red 1-10 part looked up to heaven.
More preferably, medicament of the present invention is to be made by weight by following bulk drugs: 2 parts, the sub-wood of 12 parts of Flos Gomphrenaes, 8 parts of Elatostema oblohgifolium Fu. (Elatostema bodinier Levl), 9 parts of XUEJINGCAO, 12 parts of Radix Aneurolepidiies, 8 parts of Herba oxalidis corymbosaes, 6 parts of Herba Erigerontis Annuis, 5 parts of Salvia roborowskii Maxims, 6 parts of Rhizoma Tupistrae Chinensis, 6 parts of Radix Stellariae Yunnanensiss, 5 parts of Herba Lysimachiae Insigniss, 3 parts of Canna generalis, 2 parts of Herba Begoniae Yunnanensis, 3 parts of horse Auricled Hedyotis Herbs, 2 parts of Dendrobium jenkinsii Wall ex Lindl．, 3 parts of Gymnema yunnanense Tsiang, 2 parts of Folium seu Fructus Tarennaes, water, 2 parts of Herba Salviae Chinensiss, 3 parts, the clock and sting blood red 2 parts of looking up to heaven.
Most preferably, described medicament can be tablet, dispersible tablet, disintegrating tablet, instant, enteric coatel tablets, capsule or decoction.
In compositions of the present invention, Flos Gomphrenae, Elatostema oblohgifolium Fu. (Elatostema bodinier Levl), XUEJINGCAO, Radix Aneurolepidii, Herba oxalidis corymbosae are monarch drug; Herba Erigerontis Annui, Salvia roborowskii Maxim, Rhizoma Tupistrae Chinensis, Radix Stellariae Yunnanensis, Herba Lysimachiae Insignis are ministerial drug; Canna generalis, Herba Begoniae Yunnanensis, horse Auricled Hedyotis Herb, Dendrobium jenkinsii Wall ex Lindl．, Gymnema yunnanense Tsiang are adjuvant drug; Folium seu Fructus Tarennae, water sub-wood, Herba Salviae Chinensis, the clock and sting blood redly for making medicine of looking up to heaven, various compositions are brought into play synergism with generation optimum efficiency.
In order to understand better the present invention, with reference to < < Chinese medicine voluminous dictionary > > second edition (Shanghai science tech publishing house, 2005) explanation of some crude drug that, use in the present invention sees the following form:
The medicament for the treatment of intractable insomnia of the present invention has clearing away heat and cooling blood, the YIN nourishing of promoting the production of body fluid, and the effect of tranquilizing by nourishing the heart, can effectively treat intractable insomnia.
The specific embodiment
Below by embodiment, further illustrate the present invention.It should be understood that embodiments of the invention are for the present invention rather than limitation of the present invention are described.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the scope of protection of present invention.Except as otherwise noted, the percent otherwise in the present invention is percetage by weight.
Embodiment decoction of the present invention
Get 2 grams, the sub-wood of 12 grams of Flos Gomphrenaes, 8 grams of Elatostema oblohgifolium Fu. (Elatostema bodinier Levl), 9 grams of XUEJINGCAO, 12 grams of Radix Aneurolepidiies, 8 grams of Herba oxalidis corymbosaes, 6 grams of Herba Erigerontis Annuis, 5 grams of Salvia roborowskii Maxims, 6 grams of Rhizoma Tupistrae Chinensis, 6 grams of Radix Stellariae Yunnanensiss, 5 grams of Herba Lysimachiae Insigniss, 3 grams of Canna generalis, 2 grams of Herba Begoniae Yunnanensis, 3 grams of horse Auricled Hedyotis Herbs, 2 grams of Dendrobium jenkinsii Wall ex Lindl．, 3 grams of Gymnema yunnanense Tsiang, 2 grams of Folium seu Fructus Tarennaes, water, 2 grams of Herba Salviae Chinensiss, 3 grams, the clock and sting blood red 2 grams of looking up to heaven, add 12000 milliliters, water, in being housed, at 80 ℃, heats 5 hours by the flask of condenser, filter, filtrate is decoction of the present invention.
Experimental example
Physical data
50 routine patients are to our hospital year August in January, 2012 to 2013, male 25 examples wherein, female's 25 examples; Age 41-65 year, average 53.8 years old; 9 months-2a of the course of disease not etc., average 1.3a.All show as difficulty falling asleep clinically and easily wake up, or being difficult to fall asleep again after waking up, can not fall asleep all night, companion's cardiopalmus, forgetful, dreaminess or have vexed.
Diagnostic criteria
With reference to < < neurological > > (Wang Weizhi, Luo Zuming. neurological [M]. Beijing: People's Health Publisher, 2005:257.) select > > (to wear careful with < < disease of tcm diagnosis and treatment standard and prescription, Xue Jianguo. disease of tcm is examined criterion of therapeutical effect and prescription is selected [M]. Beijing: People's Health Publisher, 2001:378-385.) middle diagnostic criteria of having a sleepless night, by patient's Symptoms, divide 3 conditions: 1. the lighter's difficulty falling asleep and easily waking up, after waking up, be difficult to fall asleep again, severe one can not be fallen asleep all night, 2. often with cardiopalmus, headache and dizziness, forgetful, dreaminess or have vexed, irritability, the symptom such as gastral cavity is swollen, feeling of fullness, loss of appetite, through each systems inspection, do not find obvious abnormal index.Get rid of period of pregnancy, menstrual phase patient.
With the decoction making in embodiment 1, treat, once a day, each oral 200 milliliters, treat continuously 10 days.
Curative effect determinate standard
The < < new Chinese medicine guideline of clinical investigations > > formulating according to Ministry of Public Health in 1993 (Ministry of Health of the People's Republic of China. new Chinese medicine guideline of clinical investigations criterion of therapeutical effect [S] .1993:186-187.) formulate criterion of therapeutical effect.Clinical cure: recover normal the length of one's sleep, or the length of one's sleep more than 6h, sleep deep, hale and hearty after waking up.Effective: be clearly better the length of one's sleep, obviously increase 3h the length of one's sleep, Depth of sleep increases.Invalid: symptom alleviates, the length of one's sleep is the not enough 3h of front increase, and after treatment, insomnia is not improved.
Result
Through treatment, find clinical cure 47 examples in 50 routine patients, effective 3 examples, total effective rate reaches 100%.And in therapeutic process, patient do not find for example to feel sick, vomits, dizzy, nervous etc. significantly untoward reaction.
Claims (4)
1. a medicament for the treatment of intractable insomnia, it is characterized in that, it is to be made by weight by following bulk drugs: Flos Gomphrenae 1-30 part, Elatostema oblohgifolium Fu. (Elatostema bodinier Levl) 1-20 part, XUEJINGCAO 1-20 part, Radix Aneurolepidii 1-20 part, Herba oxalidis corymbosae 1-20 part, Herba Erigerontis Annui 1-20 part, Salvia roborowskii Maxim 1-20 part, Rhizoma Tupistrae Chinensis 1-20 part, Radix Stellariae Yunnanensis 1-20 part, Herba Lysimachiae Insignis 1-20 part, Canna generalis 1-20 part, Herba Begoniae Yunnanensis 1-20 part, horse Auricled Hedyotis Herb 1-20 part, Dendrobium jenkinsii Wall ex Lindl． 1-20 part, Gymnema yunnanense Tsiang 1-20 part, Folium seu Fructus Tarennae 1-20 part, the sub-wooden 1-20 part of water, Herba Salviae Chinensis 1-20 part, look up to heaven clock 1-20 part and thorn blood red 1-20 part.
2. the medicament for the treatment of intractable insomnia according to claim 1, it is characterized in that, it is to be made by weight by following bulk drugs: Flos Gomphrenae 1-20 part, Elatostema oblohgifolium Fu. (Elatostema bodinier Levl) 1-15 part, XUEJINGCAO 1-15 part, Radix Aneurolepidii 1-15 part, Herba oxalidis corymbosae 1-15 part, Herba Erigerontis Annui 1-15 part, Salvia roborowskii Maxim 1-15 part, Rhizoma Tupistrae Chinensis 1-15 part, Radix Stellariae Yunnanensis 1-15 part, Herba Lysimachiae Insignis 1-15 part, Canna generalis 1-15 part, Herba Begoniae Yunnanensis 1-10 part, horse Auricled Hedyotis Herb 1-10 part, Dendrobium jenkinsii Wall ex Lindl． 1-10 part, Gymnema yunnanense Tsiang 1-10 part, Folium seu Fructus Tarennae 1-10 part, the sub-wooden 1-10 part of water, Herba Salviae Chinensis 1-10 part, look up to heaven clock 1-10 part and thorn blood red 1-10 part.
3. the medicament for the treatment of intractable insomnia according to claim 2, it is characterized in that, it is to be made by weight by following bulk drugs: 2 parts, the sub-wood of 12 parts of Flos Gomphrenaes, 8 parts of Elatostema oblohgifolium Fu. (Elatostema bodinier Levl), 9 parts of XUEJINGCAO, 12 parts of Radix Aneurolepidiies, 8 parts of Herba oxalidis corymbosaes, 6 parts of Herba Erigerontis Annuis, 5 parts of Salvia roborowskii Maxims, 6 parts of Rhizoma Tupistrae Chinensis, 6 parts of Radix Stellariae Yunnanensiss, 5 parts of Herba Lysimachiae Insigniss, 3 parts of Canna generalis, 2 parts of Herba Begoniae Yunnanensis, 3 parts of horse Auricled Hedyotis Herbs, 2 parts of Dendrobium jenkinsii Wall ex Lindl．, 3 parts of Gymnema yunnanense Tsiang, 2 parts of Folium seu Fructus Tarennaes, water, 2 parts of Herba Salviae Chinensiss, 3 parts, the clock and sting blood red 2 parts of looking up to heaven.
4. according to the medicament of the treatment intractable insomnia described in any one in claims 1 to 3, it is characterized in that, described medicament can be tablet, dispersible tablet, disintegrating tablet, instant, enteric coatel tablets, capsule or decoction.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410000558.XA CN103705780B (en) | 2014-01-02 | 2014-01-02 | A kind of medicament for the treatment of intractable insomnia |
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| CN201410000558.XA CN103705780B (en) | 2014-01-02 | 2014-01-02 | A kind of medicament for the treatment of intractable insomnia |
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| CN103705780A true CN103705780A (en) | 2014-04-09 |
| CN103705780B CN103705780B (en) | 2015-09-16 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101595515B1 (en) * | 2014-11-10 | 2016-02-19 | 주식회사 엔에스웰니스 | Composition for Preventing or Treating Stress-Related Diseases Comprising Annual fleabane Extracts as Active Ingredients |
| KR101641902B1 (en) * | 2015-06-24 | 2016-07-22 | 주식회사 네이처센스 농업회사법인 | Composition for releasing stress |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101390612A (en) * | 2008-03-29 | 2009-03-25 | 蓝子花 | Caltrop starch health-care noodle |
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2014
- 2014-01-02 CN CN201410000558.XA patent/CN103705780B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101390612A (en) * | 2008-03-29 | 2009-03-25 | 蓝子花 | Caltrop starch health-care noodle |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101595515B1 (en) * | 2014-11-10 | 2016-02-19 | 주식회사 엔에스웰니스 | Composition for Preventing or Treating Stress-Related Diseases Comprising Annual fleabane Extracts as Active Ingredients |
| KR101641902B1 (en) * | 2015-06-24 | 2016-07-22 | 주식회사 네이처센스 농업회사법인 | Composition for releasing stress |
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| CN103705780B (en) | 2015-09-16 |
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