CN102488797B - Medicinal composition for treating dysmenorrhea - Google Patents
Medicinal composition for treating dysmenorrhea Download PDFInfo
- Publication number
- CN102488797B CN102488797B CN 201110407153 CN201110407153A CN102488797B CN 102488797 B CN102488797 B CN 102488797B CN 201110407153 CN201110407153 CN 201110407153 CN 201110407153 A CN201110407153 A CN 201110407153A CN 102488797 B CN102488797 B CN 102488797B
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- Prior art keywords
- medicinal composition
- dysmenorrhea
- medicines
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- Expired - Fee Related
Links
- 206010013935 Dysmenorrhoea Diseases 0.000 title claims abstract description 18
- 208000005171 Dysmenorrhea Diseases 0.000 title claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 19
- 229940079593 drug Drugs 0.000 claims abstract description 8
- 239000008194 pharmaceutical composition Substances 0.000 claims description 6
- 230000000694 effects Effects 0.000 abstract description 3
- 238000002360 preparation method Methods 0.000 abstract description 3
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 240000005528 Arctium lappa Species 0.000 abstract 1
- 235000003130 Arctium lappa Nutrition 0.000 abstract 1
- 235000008078 Arctium minus Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 240000006891 Artemisia vulgaris Species 0.000 abstract 1
- 241000202903 Bergenia purpurascens Species 0.000 abstract 1
- 240000007371 Cuscuta campestris Species 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 241000830535 Ligustrum lucidum Species 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract 1
- 235000006753 Platycodon grandiflorum Nutrition 0.000 abstract 1
- 240000003582 Platycodon grandiflorus Species 0.000 abstract 1
- 241000304432 Sedum sarmentosum Species 0.000 abstract 1
- 240000008866 Ziziphus nummularia Species 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 229940126672 traditional medicines Drugs 0.000 abstract 1
- 230000010354 integration Effects 0.000 description 6
- 208000002193 Pain Diseases 0.000 description 5
- 230000036407 pain Effects 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 206010000087 Abdominal pain upper Diseases 0.000 description 4
- 238000011835 investigation Methods 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 210000004392 genitalia Anatomy 0.000 description 3
- 230000003821 menstrual periods Effects 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000027758 ovulation cycle Effects 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- 206010042772 syncope Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- XOJVHLIYNSOZOO-SWOBOCGESA-N Arctiin Chemical compound C1=C(OC)C(OC)=CC=C1C[C@@H]1[C@@H](CC=2C=C(OC)C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)=CC=2)C(=O)OC1 XOJVHLIYNSOZOO-SWOBOCGESA-N 0.000 description 1
- 206010009866 Cold sweat Diseases 0.000 description 1
- 206010013082 Discomfort Diseases 0.000 description 1
- 208000002513 Flank pain Diseases 0.000 description 1
- 208000036365 Normal labour Diseases 0.000 description 1
- 235000003143 Panax notoginseng Nutrition 0.000 description 1
- 241000180649 Panax notoginseng Species 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000002498 deadly effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000006196 drop Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 208000024756 faint Diseases 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Abstract
The invention relates to a medicinal composition for treating dysmenorrhea. The medicinal composition is a medicament which is prepared from the following raw material medicines: burdock, dodder, pseudo-ginseng, rhizoma alismatis, seed of wild jujube, stringy stonecrop, balloon flower, mugwort leaf, angelica, liquoric root, purple bergenia and glossy privet fruit. The medicinal composition provided by the invention is prepared from pure Chinese traditional medicines by using the conventional preparation method, so that the property of the medicines is remained, the curative effect is clear, and the dysmenorrheal can be effectively treated.
Description
Technical field
The present invention relates to field of medicaments, specifically, relate to a kind of pharmaceutical composition for the treatment of dysmenorrhea.
Background technology
Dysmenorrhea refers to that the women in menstrual period and front and back thereof, lower abdomen or flank pain occur, even pain and waist sacrum.Often send out with menstrual cycle, severe patient can be accompanied nausea and vomiting, dripping cold sweat, deadly cold hand and foot, even faints, and brings impact for work and life.Present clinical two kinds of constitutional and the Secondary cases that often it are divided into, primary dysmenorrhea refer to that the genitals without obvious pathological changes person, therefore claim again primary dysmenorrhea, is more common in adolescence, the unmarried and married person of not educating more.Many can the alleviation or disappear of this kind dysmenorrhea pain after normal labor.Secondary dysmenorrhea is many to be had due to organic disease because of the genitals.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition for the treatment of dysmenorrhea.
In order to realize purpose of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of dysmenorrhea, it is made by weight by following bulk drugs:
Preferably, it is made by weight by following bulk drugs:
Preferably, described medicament is tablet, capsule, soft capsule, pill, granule, drop pill or decoction.
Pharmaceutical composition of the present invention adopts traditional manufacture method with pure traditional Chinese medicine, has kept the property of medicine of medicine, and curative effect is clear and definite, can effectively treat dysmenorrhea.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 decoction of the present invention
Get Fructus Arctii 100 grams, Semen Cuscutae 100 grams, Radix Notoginseng 30 grams, Rhizoma Alismatis 30 grams, Semen Ziziphi Spinosae 100 grams, Herba Sedi 50 grams, Radix Platycodonis 50 grams, Folium Artemisiae Argyi 100 grams, Radix Angelicae Sinensis 50 grams, Radix Glycyrrhizae 50 grams, Rhizoma Seu Herba Bergeniae 100 grams, Fructus Ligustri Lucidi 100 grams, be placed in 2000 ml waters, 100 ℃ of lower reflux 2 hours, filter, obtain filtering residue and filtrate.Described filtrate is concentrated into 500 milliliters, and get final product.
Experimental example
Diagnostic criteria is made a definite diagnosis with reference to the diagnostic criteria in " Gynecology of Chinese Medicine ".Periodically lower abdomen pain appears in the women before and after menstrual period or menstrual period, pain is drawn the waist energy, and even severe pain causes the person of fainting, and with other discomforts, so that affect work and life.Married women is through gynecologial examination, and unmarried female is through B-mode ultrasonography, all get rid of genitals's organic disease (the Zheng Xiao cornel. new Chinese medicine guideline of clinical investigations (trying) [S]. Beijing: Chinese Medicine science and technology publishing house, 2002:168.).According to " new Chinese medicine guideline of clinical investigations " dysmenorrhea degree divide gently, in, weigh 3 grades (Ministry of Health of the People's Republic of China. new Chinese medicine guideline of clinical investigations: the 1st volume of [S] .1993:252.).
Choose 60 examples that meet above-mentioned standard, unmarried 46 examples, married 14 examples; Minimum 12 years old of age, maximum 24 years old; The course of disease 3 months-6 years.
Therapeutic scheme
Treatment group: the decoction that uses preparation in embodiment 1.Take each 20 milliliters every day 2 times.2 weeks were 1 course for the treatment of.
Criterion of therapeutical effect
By dysmenorrhea clinical index integration, with the state of an illness be divided into gently (＜8 minutes), in (8-13.5 divides), weight (〉=13.5 minutes).Medication was passed judgment on after 1 course for the treatment of.Recovery from illness: stomachache and other transference cures, 3 menstrual cycle of drug withdrawal do not recur, and dysmenorrhea clinical symptoms integration is 0; Produce effects: stomachache obviously alleviates, and other transference cures or alleviate refuse to obey that analgesic can adhere to work, 1/2 of the front integration of dysmenorrhea clinical symptoms integration≤treatment; Effectively: stomachache alleviates, and other symptoms take a turn for the better, and takes analgesic and can adhere to work, 1/3 of the front integration of dysmenorrhea clinical symptoms integration≤treatment; Invalid: stomachache and other symptoms without change (Ministry of Health of the People's Republic of China. new Chinese medicine guideline of clinical investigations: the 1st volume of [S] .1993:252.).
Treat the result after a course for the treatment of:
All patients all meet the treatment standard of recovery from illness, and do not observe obvious untoward reaction in therapeutic process.
Claims (1)
1. a pharmaceutical composition for the treatment of dysmenorrhea, is characterized in that, it is the medicament of being made by weight by following bulk drugs:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110407153 CN102488797B (en) | 2011-12-09 | 2011-12-09 | Medicinal composition for treating dysmenorrhea |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110407153 CN102488797B (en) | 2011-12-09 | 2011-12-09 | Medicinal composition for treating dysmenorrhea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102488797A CN102488797A (en) | 2012-06-13 |
| CN102488797B true CN102488797B (en) | 2013-06-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110407153 Expired - Fee Related CN102488797B (en) | 2011-12-09 | 2011-12-09 | Medicinal composition for treating dysmenorrhea |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102488797B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103041345A (en) * | 2012-12-31 | 2013-04-17 | 王爱云 | Agent for treating dysmenorrhea |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101461921A (en) * | 2008-12-31 | 2009-06-24 | 云南白药集团股份有限公司 | Medicinal composition for treating gynecopathy |
-
2011
- 2011-12-09 CN CN 201110407153 patent/CN102488797B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101461921A (en) * | 2008-12-31 | 2009-06-24 | 云南白药集团股份有限公司 | Medicinal composition for treating gynecopathy |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102488797A (en) | 2012-06-13 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: TIANJIANG PHARMACEUTICAL INDUSTRY CO., LTD., JIANG Free format text: FORMER OWNER: XU HAIYAN Effective date: 20130814 |
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| C41 | Transfer of patent application or patent right or utility model | ||
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Free format text: CORRECT: ADDRESS; FROM: 272111 JINING, SHANDONG PROVINCE TO: 214400 WUXI, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20130814 Address after: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee after: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin Address before: 6 obstetrics and Gynecology, the first people's Hospital of Shandong, Jining province 272111 Jining health center, Shandong Patentee before: Xu Haiyan |
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| TR01 | Transfer of patent right |
Effective date of registration: 20170614 Address after: 226500, No. 999, Wanshou South Road, Rugao City, Jiangsu province (room 3A08-26, building 8, hi tech Zone, Nantong) Patentee after: Jiangsu hundred sword Pharmaceutical Technology Co., Ltd. Address before: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee before: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin |
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| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130612 Termination date: 20201209 |
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| CF01 | Termination of patent right due to non-payment of annual fee |