CN103705740B - 一种治疗热秘型便秘的中药组合物 - Google Patents
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Abstract
本发明公开了一种治疗热秘型便秘的中药组合物。中医认为热秘是燥热内结，灼伤津液，腑气不通，而致肠道郁热，失于濡润，传导不利而致。其发病原因是素体阳盛，或多食辛辣之食物，热病之后，余热留恋，耗伤津液所致。本发明选择具有养阴生津，润肠清热，行气除满的中药硬飘拂草、独叶一枝花、黄脚鸡、山大黄、凤尾搜山虎、蚌壳草根、火麻仁、杧果叶、梧桐子、大鹅儿肠，水煎成汤剂，经临床试验，总有效率为98％，疗效显著，且治疗过程中没有明显不良反应。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗热秘型便秘的中药组合物。
背景技术
便秘(constipation)是指排便频率减少，一周内大便次数少于2～3次，或者2～3天才大便1次，粪便量少且干结时称为便秘。热秘多见于中青年患者，18～49岁为最多，占83.3％，尤以妇女产后多见，是产科三大难病之一，发病率男女之比例1∶4，男女差异较大。热秘好发于素体阳盛、嗜酒、喜食辛辣食物或热病之后的人的身上。中医中药在治疗便秘方面所发挥的是综合疗效，现代中药药理研究发现，多种中药所富含的活性成分不仅作用于消化系统的不同环节，更可多靶点的调节生理机能，使机体趋于平衡，对机体副反应小，作用持久，取得了较好的疗效。
发明内容
本发明的目的是提供一种治疗热秘型便秘的中药组合物。在历代医籍中，便秘又有“实秘”、“虚秘”、“气秘”、“风秘”、“痰秘”、“冷秘”、“热秘”、“三焦秘”、“幽门秘”、“直肠结”、“脾约”之分。中医学认为便秘是由于大肠传导功能失常所致，其病位在于大肠，与肺、肝、脾、肾关系至为密切，其病机变化有虚有实，有寒有热，涉及气血阴阳。中医认为热秘是燥热内结，灼伤津液，腑气不通，而致肠道郁热，失于濡润，传导不利而致。其发病原因是素体阳盛，或多食辛辣之食物，热病之后，余热留恋，耗伤津液所致。治以养阴生津，润肠清热，行气除满。
本发明的目的是通过以下技术方案实现的，该治疗热秘型便秘的中药组合物由以下重量份的中药制成：硬飘拂草9-15份、独叶一枝花20-25份、黄脚鸡17-20份、山大黄8-14份、凤尾搜山虎3-6份、蚌壳草根9-15份、火麻仁12-16份、杧果叶5-15份、梧桐子3-9份、大鹅儿肠10-15份。
优选的：硬飘拂草12份、独叶一枝花23份、黄脚鸡19份、山大黄11份、凤尾搜山虎5份、蚌壳草根12份、火麻仁14份、杧果叶10份、梧桐子6份、大鹅儿肠12份。
制备方法将上述中药水煎制成汤剂。
方中：硬飘拂草滋阴润燥、补虚益损；独叶一枝花滋阴润肺、活血；黄脚鸡滋阴生津；山大黄泻热通便、破积行瘀；凤尾搜山虎通便降火、消积活络；蚌壳草根清热除湿、消疳止咳；火麻仁润燥滑肠、通淋活血；杧果叶行气疏滞、去瘀积；梧桐子顺气和胃、消食；大鹅儿肠理气化湿、消积活血、止血。
临床资料
1.一般资料本组50例均为门诊病例，均符合《中医病症诊断疗效标准》，其中男13例，女37例；年龄最大68岁，最小19岁，平均38.9岁，临床表现是大便次数减少，经常3～7天，甚至更久才能大便一次，或者虽然次数不减，但粪质干燥坚硬，排出困难为主要症状。
2.诊断标准中医辩证症候：大便干结，排便困难；口苦口干；小便短赤；间隔时间延长，甚则肛裂便血；舌红、苔黄；脉滑数。
3.治疗方法患者服用本发明所述的中药组合物，称取硬飘拂草12g、独叶一枝花23g、黄脚鸡19g、山大黄11g、凤尾搜山虎5g、蚌壳草根12g、火麻仁14g、杧果叶10g、梧桐子6g、大鹅儿肠12g，水煎成汤剂，每日一剂，分早晚2次服用，连用7天为一个疗程。
4.疗效标准根据《中药新药临床研究指导原则》拟定。临床治愈：大便正常，或恢复至病前水平，其它症状全部消失。显效：便秘明显改善，排便间隔时间及便质接近正常；或大便稍干而排便间隔在72小时以内，其它症状大部分消失。有效：排便间隔时间缩短1天，或便质干结改善，其它症状均有好转。无效：便秘及其它症状均无改善。
5.治疗效果患者治疗1个疗程后观察疗效。其中治愈26例(52％)，显效13例(26％)，有效10例(20％)，无效1例(2％)，总有效率为98％。患者治疗过程中没有明显不良反应。
具体实施方式
实施例一：称取硬飘拂草12g、独叶一枝花23g、黄脚鸡19g、山大黄11g、凤尾搜山虎5g、蚌壳草根12g、火麻仁14g、杧果叶10g、梧桐子6g、大鹅儿肠12g，将上述中药水煎成汤剂。
实施例二：称取硬飘拂草15g、独叶一枝花25g、黄脚鸡20g、山大黄14g、凤尾搜山虎6g、蚌壳草根9g、火麻仁16g、杧果叶5g、梧桐子9g、大鹅儿肠10g，将上述中药水煎成汤剂。
实施例三：称取硬飘拂草9g、独叶一枝花20g、黄脚鸡17g、山大黄8g、凤尾搜山虎3g、蚌壳草根15g、火麻仁12g、杧果叶15g、梧桐子3g、大鹅儿肠15g，将上述中药水煎成汤剂。
Claims (2)
1.一种治疗热秘型便秘的中药组合物，其特征在于该中药组合物由以下重量份的中药制成：硬飘拂草9-15份、独叶一枝花20-25份、黄脚鸡17-20份、山大黄8-14份、凤尾搜山虎3-6份、蚌壳草根9-15份、火麻仁12-16份、杧果叶5-15份、梧桐子3-9份、大鹅儿肠10-15份。
2.根据权利要求1所述的一种治疗热秘型便秘的中药组合物，其特征在于该中药组合物由以下重量份的中药制成：硬飘拂草12份、独叶一枝花23份、黄脚鸡19份、山大黄11份、凤尾搜山虎5份、蚌壳草根12份、火麻仁14份、杧果叶10份、梧桐子6份、大鹅儿肠12份。
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