CN103690847B - A kind of Chinese medicine for the treatment of allergic vasculitis - Google Patents
A kind of Chinese medicine for the treatment of allergic vasculitis Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine for the treatment of allergic vasculitis, be prepared from by the medical material of following weight proportion: relieve internal heat grass 12 parts, Ramulus et Folium Vaccinii Bracteati 15 parts, Herba Brachiariae Villoae 20 parts, cigarette Flos edgeworthiae 30 parts, Rhizoma Begoniae Willsonii 15 parts, southwestern Rhizoma Smilacis Bockii 6 parts, Herba lagopsis supinae 10 parts, Herba Haloragidis Micranthae 20 parts, Sabia fasciculata Lecomte et L.Chen 10 parts, Herba leucadis ciliatae 15 parts, Radix Dipsaci 6 parts, roll dragon grass 9 parts.Clinical trial certificate, the present invention can safe and effective treatment allergic vasculitis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of allergic vasculitis.
Background technology
Allergic vasculitis (allergicvasculitis) is more common a kind of disease, and clinical characters is acute attack, chronic process, is a kind of stubborn disease, normal recurrent exerbation, the course of disease is delayed difficult.Its histopathology has leukocyte core broken, has skin injury, also has multiple visceral injury.Primary disease weight differs, and the lighter only has skin lesion, and several weeks can heal, and severe patient can have multi viscera impaired, even threat to life.Based on lower limb generation erythema nodosum, there is tenderness, also can with skin lesion such as purpura, purpuric pimple, welt, mound blebs.Pathogenic factors is more and complicated, it is generally acknowledged mainly because medicine or infection cause.
The effective medicine of generally recognized as safe is still lacked at present for allergic vasculitis.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Relieve internal heat grass [source] for Hemionitidaceae plant Er Yejinmao psilophyton GymnopterisbipinnataChristvar.auriculata (Franch.) Ching [GymnogrammevestitaHook.var.auriculataFranch.] rhizome or herb.Annual or summer, autumn gather, and clean, using fresh herb or dry.[function cures mainly] detoxifies; Dampness removing to stop itchin.Main air skin infection is itched; Eczema; Leukorrhagia.
Ramulus et Folium Vaccinii Bracteati [source] is Cuculidae plant southwest Pericarpium Citri tangerinae VacciniumlaetumDiels [V.mandarinorumDielsvar.laetum (Diels) Metc; V.sprengelii (G.Don) sleumer; V.laetumDielsvar.undula-tumY.C.Yang] branch and leaf.The whole year can adopt, and sections dries.The pain relieving of [function cures mainly] suppressing the hyperactive liver.Main migraine.
Herba Brachiariae Villoae [source] is the herb of standing grain arm graminaceous plant Herba Brachiariae Villoae Brachiariavillosa (Lam.) A.Camus.Summer, autumn gather, using fresh herb or dry.[function cures mainly] clearing away heat and promoting diuresis; Relieving constipation.Main hot urination; Constipation.
Cigarette Flos edgeworthiae [source] is the herb of Pontederiaceae plant Herba Monochoriae hastatae Monochoriahastata (L.) Solms [PontederiahastataL.].Spring, summer gather, and using fresh herb or cutting are dried.[function cures mainly] clearing away heat-damp and promoting diuresis; Removing toxic substances; Detumescence.Main dysentery; Have loose bowels; Laryngopharynx swelling and pain; Carbuncle furuncle; Venom.
The rhizome of Rhizoma Begoniae Willsonii [source] Begoniaceae plant Rhizoma Begoniae Willsonii Flos Begoniae Evansianae BegoniawilsoniiGagn..Take rhizome after autumn, clean, section, dries or using fresh herb.[function cures mainly] is nourished blood and is enriched blood; Eliminating stasis to stop pain.Main weak after being ill; Impairment caused by overstrain; Blood deficiency amenorrhea; Metrorrhagia; Leucorrhea; Spit blood; Spitting of blood; Epistaxis; Traumatic hemorrhage; Treating swelling and pain by traumatic injury.
Southwest Rhizoma Smilacis Bockii [source] is the rhizome of liliaceous plant southwest greenbrier SmilaxbockiiWarb.The 8-9 month excavates, and cleans, and section, dries.[function cures mainly] expelling wind and removing dampness; Blood circulation promoting and blood stasis dispelling; Detoxicating and resolving stagnation of pathogens.Main air arthralgia chiefly caused by damp pathogen is demonstrate,proved; Treating swelling and pain by traumatic injury; Furuncle scrofula.
Herba lagopsis supinae [source] is the herb of labiate Herba lagopsis supinae Lagopsissupina (Stiph.) IK.-Gal. [MarrubiumincisumBenth.].Before the Summer Solstice, full-bloom stage is gathered, and dries or using fresh herb.[function cures mainly] nourshing blood and promoting blood circulation; Clearing away heat-damp and promoting diuresis.Main menoxenia; The stagnant stomachache of the stasis of blood in puerperal; Blood deficiency is dizzy; It is unsuccessful partly to penetrate; Traumatic injury; Edema; Dysuria; Conjunctival congestion and swelling pain; Carbuncle sore; Chilblain; Toothache; Erythra pruritus.
Herba Haloragidis Micranthae [source] is the herb of Haloragaceae plant Herba Haloragidis Micranthae Haloragismicrantha (Thunb.) R.Br.exSidb.EtZucc. [GoniocarpusmicranthusThunb.].To gather summer herb, clean using fresh herb or dry.[function cures mainly] relieving cough and asthma; Clearing away heat-damp and promoting diuresis; Regulating menstruation and activating blood.Main cough; Asthma; Pyretic stranguria; Constipation; Dysentery; Menoxenia; Fall and damage fracture; Furuncle; Acute mastitis; Scald; Venom.
Sabia fasciculata Lecomte et L.Chen [source] is the Herb of Sabiaceae plant bunch flower Caulis Sinomenii SabiafasciculataLecomteetL.Chen.Annual or autumn, gather winter, clean, section, dries.[function cures mainly] expelling wind and removing dampness; Dissipating blood stasis for subsidence of swelling.Main air pain of dampness syndrome; Traumatic injury congestive edema.
The herb that Herba leucadis ciliatae [source] is labiate Herba leucadis ciliatae LeucasciliataBenth..The 7-10 month gathers, and is cut into the segment being about 1cm, dries.[function cures mainly] dispersing liver and promoting blood circulation; By wind improving eyesight; Removing toxic substances.Housewife female's blood stasis amenorrhea; The pain over the hypochondriac region; Night blindness in children; Optic atrohic blindness cataracta; Swollen ulcer drug; Syphilis of the bone; Scabies; Erythra.
Radix Dipsaci [source] is the root of Dipsacaceae plant Radix Dipsaci DipsacusasperoidesC.Y.ChengetT.M.Ai..Autumn sowing is gathered on the 3rd year, to sow in spring the 2nd year results, excavate before frost, full root has been dug, removing earth, toast with fire or dry, also fresh can be put in boiling water or food steamer taking-up when steaming or scald slightly soft to root, pile up, let alone fermentation with rice straw mulching and enter to the strain of grass upper generation water, spread out again and dry or bake to absolutely dry, remove fibrous root, earth.[function cures mainly] invigorating the liver and kidney; Bone and muscle strengthening; Blood circulation regulating; Only metrorrhagia.Main aching pain in waist and back; Podomere flaccidity syndrome and arthralgia syndrome; Fall flutter wound, damage muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer swell.
Roll the herb that dragon grass [source] is hymenophyllaceae plant Trichomanes fargesii christ TrichomanesfargesiiChrist [Vandenboschiafargesii (Christ) Ching].Summer, autumn gather, and dry.[function cures mainly] heat clearing away; Removing heat from blood.Main haematemesis; Have blood in stool; Hematuria; Stranguria with turbid discharge.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of allergic vasculitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing allergic vasculitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of allergic vasculitis, it is characterized in that, be prepared from by the medical material of following weight proportion: relieve internal heat grass 12 parts, Ramulus et Folium Vaccinii Bracteati 15 parts, Herba Brachiariae Villoae 20 parts, cigarette Flos edgeworthiae 30 parts, Rhizoma Begoniae Willsonii 15 parts, southwestern Rhizoma Smilacis Bockii 6 parts, Herba lagopsis supinae 10 parts, Herba Haloragidis Micranthae 20 parts, Sabia fasciculata Lecomte et L.Chen 10 parts, Herba leucadis ciliatae 15 parts, Radix Dipsaci 6 parts, roll dragon grass 9 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects the inpatient of 56 routine allergic vasculitis-2011 years in January, 2009 altogether between JIUYUE, age 20-56 year ,-4 years March of the course of disease.Be divided at random: treatment group 30 example, blank group 26 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: course inflammatory activity performance disappears, and erythra, subcutaneous nodule and erythema disappear, and skin ulcer heals.Take a turn for the better: course inflammatory activity performance disappears, and skin ulcer heals, and skin lesion disappears more than 70%, without pain of itching.Invalid: symptom is not improved.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment allergic vasculitis.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: relieve internal heat grass 12 grams, Ramulus et Folium Vaccinii Bracteati 15 grams, Herba Brachiariae Villoae 20 grams, cigarette Flos edgeworthiae 30 grams, Rhizoma Begoniae Willsonii 15 grams, southwestern Rhizoma Smilacis Bockii 6 grams, Herba lagopsis supinae 10 grams, Herba Haloragidis Micranthae 20 grams, Sabia fasciculata Lecomte et L.Chen 10 grams, Herba leucadis ciliatae 15 grams, Radix Dipsaci 6 grams, roll dragon grass 9 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of allergic vasculitis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: relieve internal heat grass 12 grams, Ramulus et Folium Vaccinii Bracteati 15 grams, Herba Brachiariae Villoae 20 grams, cigarette Flos edgeworthiae 30 grams, Rhizoma Begoniae Willsonii 15 grams, southwestern Rhizoma Smilacis Bockii 6 grams, Herba lagopsis supinae 10 grams, Herba Haloragidis Micranthae 20 grams, Sabia fasciculata Lecomte et L.Chen 10 grams, Herba leucadis ciliatae 15 grams, Radix Dipsaci 6 grams, roll dragon grass 9 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of allergic vasculitis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: relieve internal heat grass 12 grams, Ramulus et Folium Vaccinii Bracteati 15 grams, Herba Brachiariae Villoae 20 grams, cigarette Flos edgeworthiae 30 grams, Rhizoma Begoniae Willsonii 15 grams, southwestern Rhizoma Smilacis Bockii 6 grams, Herba lagopsis supinae 10 grams, Herba Haloragidis Micranthae 20 grams, Sabia fasciculata Lecomte et L.Chen 10 grams, Herba leucadis ciliatae 15 grams, Radix Dipsaci 6 grams, roll dragon grass 9 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of allergic vasculitis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. treat the Chinese medicine of allergic vasculitis for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: relieve internal heat grass 12 parts, Ramulus et Folium Vaccinii Bracteati 15 parts, Herba Brachiariae Villoae 20 parts, cigarette Flos edgeworthiae 30 parts, Rhizoma Begoniae Willsonii 15 parts, southwestern Rhizoma Smilacis Bockii 6 parts, Herba lagopsis supinae 10 parts, Herba Haloragidis Micranthae 20 parts, Sabia fasciculata Lecomte et L.Chen 10 parts, Herba leucadis ciliatae 15 parts, Radix Dipsaci 6 parts, roll dragon grass 9 parts.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103735795A (en) * | 2013-12-14 | 2014-04-23 | 黄根强 | Traditional Chinese medicine for treating allergic vasculitis |
| CN105497527A (en) * | 2014-10-28 | 2016-04-20 | 干银荣 | Traditional Chinese medicine for treating allergic vasculitis |
| CN105535570A (en) * | 2015-09-17 | 2016-05-04 | 刘波 | Traditional Chinese medicine for treating cutaneous allergic nodular vasculitis |
| CN107890535A (en) * | 2018-01-08 | 2018-04-10 | 孙国锐 | A kind of Chinese herbal medicine ointment for being used to treat vasculitis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103127302A (en) * | 2011-12-01 | 2013-06-05 | 鲜丹科 | Inflammatory sensitization wine |
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| CN103127302A (en) * | 2011-12-01 | 2013-06-05 | 鲜丹科 | Inflammatory sensitization wine |
Non-Patent Citations (1)
| Title |
|---|
| "崔公让中药治疗变应性皮肤血管炎32例";吴建萍等;《辽宁中医杂志》;20101231;第37卷(第11期);2171-2172 * |
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Inventor after: Zhang Liqin Inventor after: Shen Yanping Inventor after: Yuan Yujun Inventor before: Huang Genqiang |
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Effective date of registration: 20160303 Address after: 265200 Laiyang Central Hospital of Yantai, Laiyang, Shandong Province, No. 111 Chang Shan Road,, China Applicant after: Zhang Liqin Applicant after: Yuan Yujun Applicant after: Shen Yanping Address before: 225500, No. 112, lotus leaf village, 1 West Bridge Village, Jiangyan Town, Jiangyan District, Jiangsu, Taizhou Applicant before: Huang Genqiang |
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Addressee: Huang Genqiang Document name: Notice of amendment |
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Granted publication date: 20160427 Termination date: 20161214 |