Summary of the invention
The object of the present invention is to provide a kind of medicinal liquid and application thereof of enema treatment chronic pelvic inflammatory disease.This medicinal liquid as secret prescription handed down in the family from generation to generation, the effect highly significant sent out in enema treatment chronic pelvic inflammatory disease.
The object of the present invention is achieved like this:
A kind of medicinal liquid of enema treatment chronic pelvic inflammatory disease, be prepared from by traditional Chinese medicinal material raw materials and antiseptic, by weight, described traditional Chinese medicinal material raw materials comprises: Semen Litchi 23-38 part, Folium Perillae 15-25 part, trident bitter root 15-25 part, Rhizoma Corydalis 10-25 part, Spina Gleditsiae 23-38 part, Fructus Foeniculi 6-12 part, Folium Artemisiae Argyi 10-25 part, Cortex Phellodendri 10-25 part, Rhizoma Imperatae 18-26 part, Semen Plantaginis 18-26 part, Semen Coicis 50-70 part, Spica Prunellae 18-26 part.
Preferably, the medicinal liquid of enema treatment chronic pelvic inflammatory disease described above, by weight, described traditional Chinese medicinal material raw materials is made up of Semen Litchi 26-34 part, Folium Perillae 18-22 part, trident bitter root 18-22 part, Rhizoma Corydalis 15-20 part, Spina Gleditsiae 26-34 part, Fructus Foeniculi 8-10 part, Folium Artemisiae Argyi 15-20 part, Cortex Phellodendri 15-20 part, Rhizoma Imperatae 20-24 part, Semen Plantaginis 20-24 part, Semen Coicis 56-70 part and Spica Prunellae 20-24 part.
In a most preferred embodiment of the present invention, the medicinal liquid of enema treatment chronic pelvic inflammatory disease described above, by weight, described traditional Chinese medicinal material raw materials is made up of Semen Litchi 30 parts, Folium Perillae 20 parts, trident bitter root 20 parts, Rhizoma Corydalis 18 parts, Spina Gleditsiae 30 parts, Fructus Foeniculi 8 parts, Folium Artemisiae Argyi 18 parts, Cortex Phellodendri 18 parts, Rhizoma Imperatae 22 parts, Semen Plantaginis 22 parts, Semen Coicis 58 parts and Spica Prunellae 22 parts.
The preparation method of the coloclysis medicinal liquid that the present invention relates to comprises the steps: to get Semen Litchi 23-38 part of recipe quantity, Folium Perillae 15-25 part, trident bitter root 15-25 part, Rhizoma Corydalis 10-25 part, Spina Gleditsiae 23-38 part, Fructus Foeniculi 6-12 part, Folium Artemisiae Argyi 10-25 part, Cortex Phellodendri 10-25 part, Rhizoma Imperatae 18-26 part, Semen Plantaginis 18-26 part, Semen Coicis 50-70 part and Spica Prunellae 18-26 part, clean roguing, dry, powder mixes, and is broken into granule; Again above-mentioned graininess medical material is added water and cover powder 2cm, soak 1-1.2h, pull medical material out and put during multi-functional extractions is filled with and decoct with water secondary, the water of first time totalling medical material 8-12 times amount, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 6-10 times amount, decoct 2h, get twice decocting liquid to merge, filter, the concentrated solution that when being concentrated into 90 DEG C, relative density (comparing water) is 1.10-1.15; Concentrated solution is set to 0-5 DEG C of deepfreeze 24h, cold preservation liquid is added the filter aid kieselguhr of 0.3%, filter, filtrate reconcentration containing 0.6-0.8g crude drug amount to every milliliter, adds appropriate antiseptic, obtains Chinese medicinal herbs decoction.
According to Chinese medicine Historical Data Data About, pharmacologically active and the source of above-mentioned Chinese crude drug are as follows:
Semen Litchi: promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving; For colic of cold type stomachache, painful and swollen testis.Select the dry mature seed of sapindaceous plant Fructus Litchi Litchi chinensis Sonn.;
Folium Perillae: expelling cold and relieving exterior syndrome, regulating the flow of QI to ease the stomach; For anemofrigid cold, headache, cough, distension and fullness of the chest and abdomen; Select the leaf of labiate wrinkle Folium Perillae, sharp Folium Perillae etc.;
Trident bitter root: heat-clearing and toxic substances removing, expelling wind and removing dampness; Control the diseases such as laryngopharynx swelling and pain, rheumatic ostalgia, malaria, jaundice, eczema, dermatitis, traumatic injury and worm venom; Select the dry root of Rutaceae Evodia plant Foliumet Ramulus Evodiae Evodia lepta (Spreng.) Merr.;
Rhizoma Corydalis: there is promoting blood circulation to remove blood stasis, effect of promoting the circulation of QI to relieve pain; Cure mainly obstruction of qi in the chest and cardialgia, the side of body rib, all pains of gastral cavity abdomen, headache, lumbago, colicky, bones and muscles pain, dysmenorrhea, amenorrhea, puerperal, the stasis of blood was suffered from abdominal pain, traumatic injury; Be selected from the tuber for papaveraceae plant corydalis;
Spina Gleditsiae: invigorate blood circulation, dispels the wind; Be used for the treatment of swollen ulcer drug, scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy; Select the dry Spina jujubae of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam.;
Fructus Foeniculi: the kidney warming warms up liver, dispersing cold for relieving pain, regulating the flow of Qi and the middle Jiao; Pungent loose temperature is led to, and in kind warm, lower two is burnt, is especially good at soothing the liver dispersing cold for relieving pain, for controlling colic of cold type key medicine; For colic of cold type stomachache, testis swelling and hanging down of either of the testes distending pain, few abdomen cold type of pain, dysmenorrhea; Select the dry mature fruit of samphire Fructus Foeniculi FoeniculumvulgareMill.;
Folium Artemisiae Argyi: dispersing cold for relieving pain, warming the meridian for stopping bleeding; For few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile, spit blood, epistaxis, metrorrhagia through many, gestation hemorrhage; External treatment skin pruritus, decortication; Select the dried leaves of feverfew Chinese mugwort Artemisia argyi Levl. et Vant.;
Cortex Phellodendri: heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat; For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus; Be selected from the dry bark of rutaceae wampee or Cortex Phellodendri;
Rhizoma Imperatae: removing heat from blood, hemostasis, heat clearing away, diuresis; Control calentura excessive thirst, spit blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice; Select the dry rhizome of grass Herba Imperatae Imperata cylindrical (L.) Beauv. var. major (Nees) C. E. Hubb.;
Semen Plantaginis: clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Improving eyesight; Eliminate the phlegm; Be used for the treatment of main dysuria; Stranguria with turbid discharge leukorrhagia; Edema distension; Heat-damp in summer dysentery; Conjunctival congestion is hidden from view; Expectorant heat syndrome cough is breathed heavily; Select the seed of Plantaginaceae plant Herba Plantaginis Big Semen Plantaginis and Plantago depressa Willd;
Semen Coicis: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal; Cure mainly edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen; Select the dry mature kernal of grass Semen Coicis (Coix lachryma-jobi L);
Spica Prunellae: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence; For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, and goiter, swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension, hyperglycemia, hyperlipidemia and high blood viscosity; Select the dry fruit ear of labiate Spica Prunellae Prunella vulgaris L.;
Medicinal liquid of the present invention is through the good absorbing effect of retention-enema treatment chronic pelvic inflammatory disease, and local application's effect can be played, medicine directly infiltrates into diseased region, can maintain long period active drug concentration, promote local blood circulation, be conducive to the absorption of inflammation foci; The warm-heat effect of medicine accelerates local blood circulation simultaneously, and local organization nutrition is improved, and treats the evident in efficacy of chronic pelvic inflammatory disease.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is done to describing further, but protection scope of the present invention be not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
Take Semen Litchi 30 parts, Folium Perillae 20 parts, trident bitter root 20 parts, Rhizoma Corydalis 18 parts, Spina Gleditsiae 30 parts, Fructus Foeniculi 8 parts, Folium Artemisiae Argyi 18 parts, Cortex Phellodendri 18 parts, Rhizoma Imperatae 22 parts, Semen Plantaginis 22 parts, Semen Coicis 58 parts, Spica Prunellae 22 parts, clean roguing, dry, be ground into granule, again above-mentioned graininess medical material is added water and cover powder 2cm, soak 1h, pull out medical material put multi-functional extraction fill with in decoct with water secondary, add up the water of medical material 12 times amount for the first time, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 10 times amount, decoct 2h, get twice decocting liquid to merge, filter, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.10, concentrated solution is put 2 DEG C of deepfreeze 24h, cold preservation liquid is added the filter aid kieselguhr of 0.3%, filter, filtrate reconcentration containing 0.6g crude drug amount to every milliliter, adds appropriate antiseptic, obtains coloclysis medicinal liquid.
Embodiment 2
Take Semen Litchi 36 parts, Folium Perillae 15 parts, trident bitter root 15 parts, Rhizoma Corydalis 20 parts, Spina Gleditsiae 38 parts, Fructus Foeniculi 6 parts, Folium Artemisiae Argyi 20 parts, Cortex Phellodendri 22 parts, Rhizoma Imperatae 26 parts, Semen Plantaginis 24 parts, Semen Coicis 50 parts, Spica Prunellae 26 parts, clean roguing, dry, be ground into granule, again above-mentioned graininess medical material is added water and cover powder 2cm, soak 1h, pull out medical material put multi-functional extraction fill with in decoct with water secondary, add up the water of medical material 10 times amount for the first time, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 10 times amount, decoct 2h, get twice decocting liquid to merge, filter, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.15, concentrated solution is put 5 DEG C of deepfreeze 24h, cold preservation liquid is added the filter aid kieselguhr of 0.3%, filter, filtrate reconcentration containing 0.8g crude drug amount to every milliliter, adds appropriate antiseptic, obtains coloclysis medicinal liquid.
Embodiment 3
Take Semen Litchi 25 parts, Folium Perillae 22 parts, trident bitter root 25 parts, Rhizoma Corydalis 10 parts, Spina Gleditsiae 32 parts, Fructus Foeniculi 12 parts, Folium Artemisiae Argyi 12 parts, Cortex Phellodendri 10 parts, Rhizoma Imperatae 26 parts, Semen Plantaginis 18 parts, Semen Coicis 70 parts, Spica Prunellae 20 parts, clean roguing, dry, be ground into granule, again above-mentioned graininess medical material is added water and cover powder 2cm, soak 1h, pull out medical material put multi-functional extraction fill with in decoct with water secondary, add up the water of medical material 10 times amount for the first time, decoct 2h, get decocting liquid, filter, second time adds up the water of medical material 8 times amount, decoct 2h, get twice decocting liquid to merge, filter, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.10, concentrated solution is put 4 DEG C of deepfreeze 24h, cold preservation liquid is added the filter aid kieselguhr of 0.3%, filter, filtrate reconcentration containing 0.6g crude drug amount to every milliliter, adds appropriate antiseptic, obtains coloclysis medicinal liquid.
Embodiment 4 liquid medicine enema is to the effectiveness study of undergoing chronic pelvic inflammation
With reference to " obstetrics and gynecology " the 7th edition undergoing chronic pelvic inflammation that chronic pelvic inflammatory disease diagnostic criteria is made a definite diagnosis 52 example, age 25-47 year, course of disease half a year to 2 year.All patients are divided into two groups at random, Chinese drug-treated group 28 example, matched group 24 example.Before treatment, the physical data such as sex, age, the course of disease, the state of an illness of two groups of patients there are no significant difference, has comparability.
The enema that Chinese drug-treated group adopts the embodiment of the present invention 1 to prepare is about 100mL and is placed in enema bag, and temperature 37 DEG C, high retension enema, every day 1 time 10 days is 1 course for the treatment of.Matched group: with normal saline l00ml+ gentamycin 160,000 unit enema treatment, 10 days be 1 course for the treatment of.Treat 3 courses for the treatment of all continuously.Menstrual phase is stopped using.
After treatment terminates, the curative effect respectively organized by following canonical statistics, the therapeutic effect of two groups of undergoing chronic pelvic inflammation is in table 1.
Cure: subjective symptoms disappear, gynecologial examination local sign (tenderness, thicken, adhesion, enclosed mass) disappear.
Effective: subjective symptoms disappears, local sign disappears substantially, and inflammatory mass reduces more than 1/2nd persons.
Take a turn for the better: subjective symptoms, local sign have alleviator.
Invalid: cardinal symptom, sign are all without changer.
Table 1 liang group comparitive study