CN103690700B - A kind of Chinese drugs agentia for the treatment of constipation and preparation method thereof - Google Patents
A kind of Chinese drugs agentia for the treatment of constipation and preparation method thereof Download PDFInfo
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- CN103690700B CN103690700B CN201310683260.9A CN201310683260A CN103690700B CN 103690700 B CN103690700 B CN 103690700B CN 201310683260 A CN201310683260 A CN 201310683260A CN 103690700 B CN103690700 B CN 103690700B
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- 206010010774 Constipation Diseases 0.000 title claims abstract description 37
- 239000003390 Chinese drug Substances 0.000 title claims abstract description 25
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 210000000582 semen Anatomy 0.000 claims abstract description 52
- 239000003814 drug Substances 0.000 claims abstract description 36
- 241000628997 Flos Species 0.000 claims abstract description 26
- 229940079593 drug Drugs 0.000 claims abstract description 23
- 235000021506 Ipomoea Nutrition 0.000 claims abstract description 13
- 241000207783 Ipomoea Species 0.000 claims abstract description 13
- 235000021551 crystal sugar Nutrition 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 239000007788 liquid Substances 0.000 claims description 15
- 238000002156 mixing Methods 0.000 claims description 15
- 238000001914 filtration Methods 0.000 claims description 10
- 238000002791 soaking Methods 0.000 claims description 10
- 238000009835 boiling Methods 0.000 claims description 7
- 239000000843 powder Substances 0.000 claims description 5
- 230000000857 drug effect Effects 0.000 abstract description 4
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 230000013872 defecation Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 210000003608 fece Anatomy 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 210000003298 dental enamel Anatomy 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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Abstract
The invention discloses a kind of Chinese drugs agentia for the treatment of constipation and preparation method thereof, be made up of according to quality meter following crude drug: Spica Prunellae 5 ~ 8 parts, Flos pandani tectorii 8 ~ 12 parts, Folium Ipomoea 10 ~ 12 parts, Semen Cassiae 10 ~ 12 parts, Flos Lonicerae 10 ~ 20 parts, Cortex Cinnamomi 6 ~ 9 parts, Fructus Momordicae 12 ~ 20 parts, Semen pini koraiensis 5 ~ 8 parts, 8 ~ 10 parts, Semen Armeniacae Amarum, Semen Juglandis 8 ~ 10 parts, 10 ~ 16 parts, crystal sugar; Compared with prior art have the following advantages: drug effect shows on the one hand, cheap, has no side effect, patient can not be caused the dependency of medicine, not easily recur; On the other hand and preparation method is easy, clinical practice is suitable for.
Description
Technical field
The present invention relates to Chinese medicine preparation and preparation method thereof, particularly relate to a kind of Chinese drugs agentia for the treatment of constipation and preparation method thereof.
Background technology
The prevalence of constipation in crowd up to 27%, but only has fraction constipation person to go to a doctor.Constipation can affect the people of each age group.Women is more than male, old more than blue or green, the prime of life.Because constipation sickness rate is high, the cause of disease is complicated, patient often has manifold vexations, and can affect quality of life when constipation is serious.Most patients is difficult to recognize that constipation is a kind of existence of disease, and carries out Drug therapy easily because reason that Western medicine side effect is large is unwilling even more thus causes the state of an illness more serious; In addition more existing Chinese medicine preparation effects are not fine yet.
Summary of the invention
Goal of the invention: in order to solve the problem existing for prior art, the invention provides that a kind of drug effect is remarkable, with low cost, the Chinese drugs agentia for the treatment of constipation that not easily recurs and preparation method thereof.
Technical scheme: for achieving the above object, the present invention is by the following technical solutions: a kind of Chinese drugs agentia for the treatment of constipation, is made up of according to quality meter following crude drug: Spica Prunellae 5 ~ 8 parts, Flos pandani tectorii 8 ~ 12 parts, Folium Ipomoea 10 ~ 12 parts, Semen Cassiae 10 ~ 12 parts, Flos Lonicerae 10 ~ 20 parts, Cortex Cinnamomi 6 ~ 9 parts, Fructus Momordicae 12 ~ 20 parts, Semen pini koraiensis 5 ~ 8 parts, 8 ~ 10 parts, Semen Armeniacae Amarum, Semen Juglandis 8 ~ 10 parts, 10 ~ 16 parts, crystal sugar.
As a further improvement on the present invention, described each crude drug consumption is composed as follows according to quality meter: Spica Prunellae 7 parts, Flos pandani tectorii 10 parts, Folium Ipomoea 11 parts, Semen Cassiae 11 parts, Flos Lonicerae 15 parts, Cortex Cinnamomi 8 parts, Fructus Momordicae 16 parts, Semen pini koraiensis 6 parts, 9 parts, Semen Armeniacae Amarum, Semen Juglandis 9 parts, 13 parts, crystal sugar.
The preparation method of the Chinese drugs agentia of above-mentioned treatment constipation, comprises the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) first Spica Prunellae, Flos pandani tectorii, Semen Cassiae, Cortex Cinnamomi four kinds of crude drug mixing and water addings are soaked, water consumption is 8 ~ 10 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 25 ~ 30min is boiled in big fire, add Folium Ipomoea, Flos Lonicerae, Fructus Momordicae again, big fire leaches medicinal liquid after boiling rear continuation decoction 15 ~ 20min, obtains filtering residue;
(3) Semen pini koraiensis, Semen Armeniacae Amarum and Semen Juglandis are ground into powder, after mixing with the filtering residue in step (2) together with crystal sugar, the water adding gross weight 3 ~ 5 times soaks, and after soaking 10min, big fire is boiled, and leaches medicinal liquid after continuing slow fire boiling 20 ~ 25min;
(4) Chinese drugs agentia of described treatment constipation is namely obtained after the medicinal liquid mixing obtained in step (2), (3).
For better ensureing decocting for Chinese herbal medicine effect, described decoction container is marmite or enamel ware.
The application of Chinese drugs agentia in preparation constipation medicine of described treatment constipation.
Beneficial effect: a kind of Chinese drugs agentia for the treatment of constipation provided by the present invention and preparation method thereof, compared with prior art has the following advantages: drug effect shows on the one hand, cheap, has no side effect, patient can not be caused the dependency of medicine, not easily recur; On the other hand and preparation method is easy, clinical practice is suitable for.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described:
Embodiment 1:
Treat a Chinese drugs agentia for constipation, be made up of according to quality meter following crude drug: Spica Prunellae 5 parts, Flos pandani tectorii 8 parts, Folium Ipomoea 10 parts, Semen Cassiae 10 parts, Flos Lonicerae 10 parts, Cortex Cinnamomi 6 parts, Fructus Momordicae 12 parts, Semen pini koraiensis 5 parts, 8 parts, Semen Armeniacae Amarum, Semen Juglandis 8 parts, 10 parts, crystal sugar.
The preparation method of the Chinese drugs agentia of above-mentioned treatment constipation, comprises the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) marmite is adopted to carry out the decoction of medicament, first Spica Prunellae, Flos pandani tectorii, Semen Cassiae, Cortex Cinnamomi four kinds of crude drug mixing and water addings are soaked, water consumption is 8 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 25min is boiled in big fire, add Folium Ipomoea, Flos Lonicerae, Fructus Momordicae again, big fire is boiled after rear continuation decocts 15min and is leached medicinal liquid, obtains filtering residue;
(3) Semen pini koraiensis, Semen Armeniacae Amarum and Semen Juglandis are ground into powder, after mixing with the filtering residue in step (2) together with crystal sugar, the water adding gross weight 3 times soaks, and after soaking 10min, big fire is boiled, and leaches medicinal liquid after continuing slow fire boiling 20min;
(4) Chinese drugs agentia of described treatment constipation is namely obtained after the medicinal liquid mixing obtained in step (2), (3).
Embodiment 2:
Treat a Chinese drugs agentia for constipation, be made up of according to quality meter following crude drug: Spica Prunellae 7 parts, Flos pandani tectorii 10 parts, Folium Ipomoea 11 parts, Semen Cassiae 11 parts, Flos Lonicerae 15 parts, Cortex Cinnamomi 8 parts, Fructus Momordicae 16 parts, Semen pini koraiensis 6 parts, 9 parts, Semen Armeniacae Amarum, Semen Juglandis 9 parts, 13 parts, crystal sugar.
The preparation method of the Chinese drugs agentia of above-mentioned treatment constipation, comprises the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) marmite is adopted to carry out the decoction of medicament, first Spica Prunellae, Flos pandani tectorii, Semen Cassiae, Cortex Cinnamomi four kinds of crude drug mixing and water addings are soaked, water consumption is 9 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 28min is boiled in big fire, add Folium Ipomoea, Flos Lonicerae, Fructus Momordicae again, big fire is boiled after rear continuation decocts 18min and is leached medicinal liquid, obtains filtering residue;
(3) Semen pini koraiensis, Semen Armeniacae Amarum and Semen Juglandis are ground into powder, after mixing with the filtering residue in step (2) together with crystal sugar, the water adding gross weight 4 times soaks, and after soaking 10min, big fire is boiled, and leaches medicinal liquid after continuing slow fire boiling 23min;
(4) Chinese drugs agentia of described treatment constipation is namely obtained after the medicinal liquid mixing obtained in step (2), (3).
Embodiment 3:
Treat a Chinese drugs agentia for constipation, be made up of according to quality meter following crude drug: Spica Prunellae 8 parts, Flos pandani tectorii 12 parts, Folium Ipomoea 12 parts, Semen Cassiae 12 parts, Flos Lonicerae 20 parts, Cortex Cinnamomi 9 parts, Fructus Momordicae 20 parts, Semen pini koraiensis 8 parts, 10 parts, Semen Armeniacae Amarum, Semen Juglandis 10 parts, 16 parts, crystal sugar.
The preparation method of the Chinese drugs agentia of above-mentioned treatment constipation, comprises the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) marmite is adopted to carry out the decoction of medicament, first Spica Prunellae, Flos pandani tectorii, Semen Cassiae, Cortex Cinnamomi four kinds of crude drug mixing and water addings are soaked, water consumption is 10 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 30min is boiled in big fire, add Folium Ipomoea, Flos Lonicerae, Fructus Momordicae again, big fire is boiled after rear continuation decocts 20min and is leached medicinal liquid, obtains filtering residue;
(3) Semen pini koraiensis, Semen Armeniacae Amarum and Semen Juglandis are ground into powder, after mixing with the filtering residue in step (2) together with crystal sugar, the water adding gross weight 5 times soaks, and after soaking 10min, big fire is boiled, and leaches medicinal liquid after continuing slow fire boiling 25min;
(4) Chinese drugs agentia of described treatment constipation is namely obtained after the medicinal liquid mixing obtained in step (2), (3).
The present invention cures mainly the constipation symptom such as defecation frequency reduces, feces amount reduces, feces is dry and hard, defecation effort.The beneficial effect of medicine of the present invention is set forth further below by way of clinical case:
(1) clinical data and Therapeutic Method
With test group treatment constipation patient 50 example, compare with matched group 50 example.
test group:chinese drugs agentia in the present invention described in embodiment 1-3, is decocted in water for oral dose, every day potion, sooner or later sub-service.Taking medicine continuously 7 days is 1 course for the treatment of;
matched group:adopt conventional medicine to treat, every day three times 7 days was 1 course for the treatment of.
Test group and matched group patient were fully recovered in 3 months and pays a return visit, investigate and record constipation disease recurrence.
(2) curative effect determinate standard
A) effective: to treat after 5 days, defecation 1 time within 2 days, just matter turns profit, and unobstructed during solution, short-term is without recurrence;
B) effective: treat after 5 ~ 7 days defecation within 3 days, just matter turns profit, and defecation is owed freely;
C) invalid: symptom, without obviously alleviating, even increases the weight of.
(3) clinical effectiveness
Test group and matched group comparitive study, in table 1.
Table 1 test group and matched group comparitive study
| Effective | Effectively | Invalid | Add up to | Effective percentage (%) | Relapse rate (%) | |
| Test group | 28 | 18 | 4 | 50 | 92 | 5 |
| Matched group | 9 | 13 | 28 | 50 | 44 | 40 |
Clinical effectiveness show: test group treatment constipation patient 50 example, total effective rate reaches 92%, in three months 5% relapse rate, with the total effective rate of matched group 50 example 44% and in three months 40% relapse rate compare, be obviously better than matched group.Illustrate that Drug therapy constipation of the present invention is evident in efficacy, drug effect significantly and not easily recur, has good promotional value.
Should be understood that, above detailed description of the invention is only not used in for illustration of the present invention and limits the scope of the invention, after having read the present invention, the amendment of those skilled in the art to the various equivalent form of value of the present invention has all fallen within the application's claims limited range.
Claims (4)
1. treat the Chinese drugs agentia of constipation for one kind, it is characterized in that, crude drug and weight proportion thereof are: Spica Prunellae 5 ~ 8 parts, Flos pandani tectorii 8 ~ 12 parts, Folium Ipomoea 10 ~ 12 parts, Semen Cassiae 10 ~ 12 parts, Flos Lonicerae 10 ~ 20 parts, Cortex Cinnamomi 6 ~ 9 parts, Fructus Momordicae 12 ~ 20 parts, Semen pini koraiensis 5 ~ 8 parts, 8 ~ 10 parts, Semen Armeniacae Amarum, Semen Juglandis 8 ~ 10 parts, 10 ~ 16 parts, crystal sugar.
2. the Chinese drugs agentia for the treatment of constipation according to claim 1, it is characterized in that, crude drug and weight proportion thereof are: Spica Prunellae 7 parts, Flos pandani tectorii 10 parts, Folium Ipomoea 11 parts, Semen Cassiae 11 parts, Flos Lonicerae 15 parts, Cortex Cinnamomi 8 parts, Fructus Momordicae 16 parts, Semen pini koraiensis 6 parts, 9 parts, Semen Armeniacae Amarum, Semen Juglandis 9 parts, 13 parts, crystal sugar.
3. a preparation method for the Chinese drugs agentia for the treatment of constipation as claimed in claim 1, is characterized in that comprising the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) first Spica Prunellae, Flos pandani tectorii, Semen Cassiae, Cortex Cinnamomi four kinds of crude drug mixing and water addings are soaked, water consumption is 8 ~ 10 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 25 ~ 30min is boiled in big fire, add Folium Ipomoea, Flos Lonicerae, Fructus Momordicae again, big fire leaches medicinal liquid after boiling rear continuation decoction 15 ~ 20min, obtains filtering residue;
(3) Semen pini koraiensis, Semen Armeniacae Amarum and Semen Juglandis are ground into powder, after mixing with the filtering residue in step (2) together with crystal sugar, the water adding gross weight 3 ~ 5 times soaks, and after soaking 10min, big fire is boiled, and leaches medicinal liquid after continuing slow fire boiling 20 ~ 25min;
(4) Chinese drugs agentia of described treatment constipation is namely obtained after the medicinal liquid mixing obtained in step (2), (3).
4. the application of Chinese drugs agentia in preparation treatment constipation medicine for the treatment of constipation according to claim 1.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310683260.9A CN103690700B (en) | 2013-12-16 | 2013-12-16 | A kind of Chinese drugs agentia for the treatment of constipation and preparation method thereof |
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| CN201310683260.9A CN103690700B (en) | 2013-12-16 | 2013-12-16 | A kind of Chinese drugs agentia for the treatment of constipation and preparation method thereof |
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| CN103690700A CN103690700A (en) | 2014-04-02 |
| CN103690700B true CN103690700B (en) | 2016-04-06 |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101513472A (en) * | 2008-02-22 | 2009-08-26 | 北京天科仁祥医药科技有限公司 | Chinese medicine preparation for mainly treating constipation |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101513472A (en) * | 2008-02-22 | 2009-08-26 | 北京天科仁祥医药科技有限公司 | Chinese medicine preparation for mainly treating constipation |
Non-Patent Citations (1)
| Title |
|---|
| 功能性便秘中医治疗进展;陈家鹏;《实用中医药杂志》;20100531;第26卷(第5期);366-367 * |
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Effective date of registration: 20160302 Address after: 325200 Wenzhou City, Ruian City, fairy street, the village of the first Village No. 115 Applicant after: Bian Jialin Address before: 266005 Shandong Province, Qingdao city Shenxian Road No. 39 room 219 Applicant before: QINGDAO BIOREGEN BIOLOGICAL ENGINEERING CO., LTD. |
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Effective date of registration: 20210128 Address after: 222200 No.12, group 15, Nangang village, tuhe Town, Guanyun County, Lianyungang City, Jiangsu Province Patentee after: Cai Shanming Address before: 325200 No. 115 Tong Tou village, Xian Jiang Street, Ruian, Wenzhou, Zhejiang Patentee before: Bian Jialin |