CN103689487B - Pomegranate bark and Chinese yam dispersible tablet and preparation method thereof - Google Patents

Pomegranate bark and Chinese yam dispersible tablet and preparation method thereof Download PDF

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CN103689487B
CN103689487B CN201310748589.9A CN201310748589A CN103689487B CN 103689487 B CN103689487 B CN 103689487B CN 201310748589 A CN201310748589 A CN 201310748589A CN 103689487 B CN103689487 B CN 103689487B
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chinese yam
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陈慧婷
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Huo Youli
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/09Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/10Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The invention discloses a pomegranate bark and Chinese yam dispersible tablet which comprises the following components in parts by weight: 100-300 parts of pomegranate bark, 100-300 parts of Chinese yam, 80-120 parts of honeysuckle, 1.75-3.75 parts of vitamin C, 0.01-0.02 part of vitamin A, 0.15-0.35 part of zinc gluconate, 40-60 parts of microcrystalline cellulose, 0.12-0.32 part of hawthorn extract, 0.12-0.32 part of American ginseng extract, 100-170 parts of mannitol, 1.2-3.2 parts of chitosan oligosaccharide, 1.2-3.2 parts of crude polysaccharide, 10-15 parts of sucralose, 10-50 parts of superfine silica powder, 3-5 parts of carboxymethyl cellulose, 55-80 parts of sodium carboxymethyl starch, 4-6 parts of magnesium stearate, appropriate amount of purified water, and an appropriate amount of 75% ethyl alcohol. The pomegranate bark and Chinese yam dispersible tablet has the effects of tonifying spleen and checking diarrhea and is suitable for infantile diarrhea.

Description

A kind of granatum Chinese yam dispersible tablet and preparation method
Technical field
The invention belongs to nutritional health food field, be specially a kind of granatum Chinese yam dispersible tablet and preparation method.
Background technology
Baby diarrhea be many cause of diseases, multifactor cause based on diarrhoea one group of disease.Main feature is that times of defecation increases and proterties changes, can with the symptoms such as heating, vomiting, stomachache and water, electrolyte, disturbance of acid-base balance in various degree.Cause of disease can by virus, bacterium, is mainly human rotavirus and other enteroviruses, enteropathogenic E. Coli, enterotoxigenic E.Coli, Enterohemorrhagic E.coli, aggressive are large
Parasite, the fungies etc. such as enterobacteria and salmonella typhimurium, campylobacter jejuni, yersinia enterocolitica, S. aureus L-forms cause.Enteric flora disturbance caused by extra intestinal infection, abuse of antibiotics, allergy, improper feeding and climatic factor also can be caused a disease.It is the common disease of 2 years old Infants Below.Although also have Chinese Traditional Medicines or the formula of a lot of baby diarrhea disease at present, although treatment prescribed preparation is a lot, be all occur with the form of medicine, the dietary product being applicable to long-term edible supplemental treatment is little.Therefore the dietary product researching and developing a kind of safe adjunct therapy is very with practical value.
Summary of the invention
For above-mentioned situation, technical problem solved by the invention is to provide a kind of granatum Chinese yam dispersible tablet and preparation method of invigorating the spleen to arrest diarrhea, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of granatum Chinese yam dispersible tablet, comprise following parts by weight ingredient: red granatum 100-300 part, Chinese yam 100-300 part, honeysuckle 80-120 part, vitamin C 1.75-3.75 part, vitamin A 0.01-0.02 part, zinc gluconate 0.15-0.35 part, microcrystalline cellulose 40-60 part, haw thorn extract 0.12-0.32 part, American ginseng extract 0.12-0.32 part, sweet mellow wine 100-170 part, chitosan oligosaccharide 1.2-3.2 part, Thick many candies 1.2-3.2 part, Sucralose 10-15 part, superfine silica gel powder 10-50 part, carboxymethyl cellulose 3-5 part, sodium carboxymethyl starch 55-80 part, dolomol 4-6 part, Purified Water q. s, 75% concentration ethanol is appropriate.
As preferably, described a kind of granatum Chinese yam dispersible tablet, comprise following parts by weight ingredient: red granatum 200 parts, Chinese yam 200 parts, honeysuckle 100 parts, vitamin C 2.75 parts, vitamin A 0.015 part, zinc gluconate 0.25 part, microcrystalline cellulose 50 parts, haw thorn extract 0.22 part, American ginseng extract 0.22 part, 135 parts, sweet mellow wine, chitosan oligosaccharide 2.2 parts, Thick many candies 2.2 parts, Sucralose 12.5 parts, superfine silica gel powder 30 parts, carboxymethyl cellulose 4 parts, sodium carboxymethyl starch 67.5 parts, dolomol 5 parts, Purified Water q. s, 75% concentration ethanol is appropriate.
A preparation method for granatum Chinese yam dispersible tablet, comprises the following steps:
(1) get after fresh Chinese yam is cleaned and soak 15-20min in the vitamin C aqueous solution of 0.1%, Chinese yam after immersion is put in freeze drier and carries out freeze drying, first open refrigerator to freeze, be chilled to raw material Chinese yam temperature within the scope of-20 to-30 DEG C, and maintain 8-10h drying, then vacuum is opened, and be heated to 95-100 DEG C, continue dry 1-3h, the solid matter that above-mentioned freeze drying obtains is pulverized, obtained Chinese yam freeze-dried powder, for subsequent use;
(2) get the red granatum of raw material, honeysuckle is cleaned, the 4-5 times amount purified water adding above-mentioned raw materials gross weight decocts 2-2.5h within the scope of 90-100 DEG C, filter, the purified water that the dregs of a decoction after filtration add 2-4 times amount is decocted 1-1.5h within the scope of 90-100 DEG C, filter, filter residue is discharged, merge twice filtrate, and carry out being concentrated into the gamma amylase adding 1-2 ‰ when proportion is 1-1.5, at 35-45 DEG C of scope inside holding 5-10h, filter after finally boiling 25-35min, obtain mixed extract, for subsequent use;
(3) be uniformly mixed by gained mixed extract in step (1) gained Chinese yam freeze-dried powder and step (2), mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, Vacuum Concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, Thick many candies, Sucralose, superfine silica gel powder mixing machine mixing make particle, rotating speed is 10-15r/min, time is 6-8min, by mixing after particle 50-60 DEG C of scope inner drying to water content between 1-3%, for subsequent use;
(6) add sodium carboxymethyl starch, dolomol mixing to gained particle in step (5), tabletted, obtains granatum Chinese yam dispersible tablet.
Get in described step (1) after fresh Chinese yam is cleaned and soak 20min in the vitamin C aqueous solution of 0.1%, Chinese yam after immersion is put in freeze drier and carries out freeze drying, first open refrigerator to freeze, be chilled to raw material Chinese yam temperature dry for maintaining 8h when-26 DEG C, then vacuum is opened, and continue dry 2.5h when being heated to 95 DEG C, the solid matter that above-mentioned freeze drying obtains is pulverized, obtained Chinese yam freeze-dried powder.
Get the red granatum of raw material in described step (2), honeysuckle is cleaned, the 6 times amount purified water adding above-mentioned raw materials gross weight decoct 2h under 90 DEG C of conditions, filter, the purified water that the dregs of a decoction after filtration add 3 times amount is decocted 1.5h under 90 DEG C of conditions, filters, filter residue is discharged, merge twice filtrate, and carry out being concentrated into the gamma amylase adding 2 ‰ when proportion is 1, under 45 DEG C of conditions, be incubated 6h, filter after finally boiling 35min, obtain mixed extract.
In sum, beneficial effect of the present invention:
The present invention has invigorating the spleen to arrest diarrhea, is applicable to baby diarrhea.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described gained technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on gained embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A kind of granatum Chinese yam dispersible tablet, comprises following parts by weight ingredient: red granatum 100 parts, Chinese yam 100 parts, honeysuckle 80 parts, vitamin C 1.75 parts, vitamin A 0.01 part, zinc gluconate 0.15-0.35 part, microcrystalline cellulose 40 parts, haw thorn extract 0.12 part, American ginseng extract 0.12 part, 100 parts, sweet mellow wine, chitosan oligosaccharide 1.2 parts, Thick many candies 1.2 parts, Sucralose 10 parts, superfine silica gel powder 10 parts, carboxymethyl cellulose 3 parts, sodium carboxymethyl starch 55 parts, dolomol 4 parts, Purified Water q. s, 75% concentration ethanol are appropriate.
A preparation method for granatum Chinese yam dispersible tablet, comprises the following steps:
(1) get after fresh Chinese yam is cleaned and soak 15-20min in the vitamin C aqueous solution of 0.1%, Chinese yam after immersion is put in freeze drier and carries out freeze drying, first open refrigerator to freeze, be chilled to raw material Chinese yam temperature within the scope of-20 to-30 DEG C, and maintain 8-10h drying, then vacuum is opened, and be heated to 95-100 DEG C, continue dry 1-3h, the solid matter that above-mentioned freeze drying obtains is pulverized, obtained Chinese yam freeze-dried powder, for subsequent use;
(2) get the red granatum of raw material, honeysuckle is cleaned, the 4-5 times amount purified water adding above-mentioned raw materials gross weight decocts 2-2.5h within the scope of 90-100 DEG C, filter, the purified water that the dregs of a decoction after filtration add 2-4 times amount is decocted 1-1.5h within the scope of 90-100 DEG C, filter, filter residue is discharged, merge twice filtrate, and carry out being concentrated into the gamma amylase adding 1-2 ‰ when proportion is 1-1.5, at 35-45 DEG C of scope inside holding 5-10h, filter after finally boiling 25-35min, obtain mixed extract, for subsequent use;
(3) be uniformly mixed by gained mixed extract in step (1) gained Chinese yam freeze-dried powder and step (2), mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, Vacuum Concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, Thick many candies, Sucralose, superfine silica gel powder mixing machine mixing make particle, rotating speed is 10-15r/min, time is 6-8min, by mixing after particle 50-60 DEG C of scope inner drying to water content between 1-3%, for subsequent use;
(6) add sodium carboxymethyl starch, dolomol mixing to gained particle in step (5), tabletted, obtains granatum Chinese yam dispersible tablet.
Embodiment 2
A kind of granatum Chinese yam dispersible tablet, comprises following parts by weight ingredient: red granatum 200 parts, Chinese yam 200 parts, honeysuckle 100 parts, vitamin C 2.75 parts, vitamin A 0.015 part, zinc gluconate 0.25 part, microcrystalline cellulose 50 parts, haw thorn extract 0.22 part, American ginseng extract 0.22 part, 135 parts, sweet mellow wine, chitosan oligosaccharide 2.2 parts, Thick many candies 2.2 parts, Sucralose 12.5 parts, superfine silica gel powder 30 parts, carboxymethyl cellulose 4 parts, sodium carboxymethyl starch 67.5 parts, dolomol 5 parts, Purified Water q. s, 75% concentration ethanol are appropriate.
A preparation method for granatum Chinese yam dispersible tablet, comprises the following steps:
(1) get after fresh Chinese yam is cleaned and soak 15-20min in the vitamin C aqueous solution of 0.1%, Chinese yam after immersion is put in freeze drier and carries out freeze drying, first open refrigerator to freeze, be chilled to raw material Chinese yam temperature within the scope of-20 to-30 DEG C, and maintain 8-10h drying, then vacuum is opened, and be heated to 95-100 DEG C, continue dry 1-3h, the solid matter that above-mentioned freeze drying obtains is pulverized, obtained Chinese yam freeze-dried powder, for subsequent use;
(2) get the red granatum of raw material, honeysuckle is cleaned, the 4-5 times amount purified water adding above-mentioned raw materials gross weight decocts 2-2.5h within the scope of 90-100 DEG C, filter, the purified water that the dregs of a decoction after filtration add 2-4 times amount is decocted 1-1.5h within the scope of 90-100 DEG C, filter, filter residue is discharged, merge twice filtrate, and carry out being concentrated into the gamma amylase adding 1-2 ‰ when proportion is 1-1.5, at 35-45 DEG C of scope inside holding 5-10h, filter after finally boiling 25-35min, obtain mixed extract, for subsequent use;
(3) be uniformly mixed by gained mixed extract in step (1) gained Chinese yam freeze-dried powder and step (2), mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, Vacuum Concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, Thick many candies, Sucralose, superfine silica gel powder mixing machine mixing make particle, rotating speed is 10-15r/min, time is 6-8min, by mixing after particle 50-60 DEG C of scope inner drying to water content between 1-3%, for subsequent use;
(6) add sodium carboxymethyl starch, dolomol mixing to gained particle in step (5), tabletted, obtains granatum Chinese yam dispersible tablet.
Embodiment 3
A kind of granatum Chinese yam dispersible tablet, comprises following parts by weight ingredient: red granatum 300 parts, Chinese yam 300 parts, honeysuckle 120 parts, vitamin C 3.75 parts, vitamin A 0.02 part, zinc gluconate 0.35 part, microcrystalline cellulose 60 parts, haw thorn extract 0.32 part, American ginseng extract 0.32 part, 170 parts, sweet mellow wine, chitosan oligosaccharide 3.2 parts, Thick many candies 3.2 parts, Sucralose 15 parts, superfine silica gel powder 50 parts, carboxymethyl cellulose 5 parts, sodium carboxymethyl starch 80 parts, dolomol 6 parts, Purified Water q. s, 75% concentration ethanol are appropriate.
A preparation method for granatum Chinese yam dispersible tablet, comprises the following steps:
(1) get after fresh Chinese yam is cleaned and soak 15-20min in the vitamin C aqueous solution of 0.1%, Chinese yam after immersion is put in freeze drier and carries out freeze drying, first open refrigerator to freeze, be chilled to raw material Chinese yam temperature within the scope of-20 to-30 DEG C, and maintain 8-10h drying, then vacuum is opened, and be heated to 95-100 DEG C, continue dry 1-3h, the solid matter that above-mentioned freeze drying obtains is pulverized, obtained Chinese yam freeze-dried powder, for subsequent use;
(2) get the red granatum of raw material, honeysuckle is cleaned, the 4-5 times amount purified water adding above-mentioned raw materials gross weight decocts 2-2.5h within the scope of 90-100 DEG C, filter, the purified water that the dregs of a decoction after filtration add 2-4 times amount is decocted 1-1.5h within the scope of 90-100 DEG C, filter, filter residue is discharged, merge twice filtrate, and carry out being concentrated into the gamma amylase adding 1-2 ‰ when proportion is 1-1.5, at 35-45 DEG C of scope inside holding 5-10h, filter after finally boiling 25-35min, obtain mixed extract, for subsequent use;
(3) be uniformly mixed by gained mixed extract in step (1) gained Chinese yam freeze-dried powder and step (2), mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, Vacuum Concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, Thick many candies, Sucralose, superfine silica gel powder mixing machine mixing make particle, rotating speed is 10-15r/min, time is 6-8min, by mixing after particle 50-60 DEG C of scope inner drying to water content between 1-3%, for subsequent use;
(6) add sodium carboxymethyl starch, dolomol mixing to gained particle in step (5), tabletted, obtains granatum Chinese yam dispersible tablet.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or essential characteristic, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and in each embodiment, gained technical scheme also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.

Claims (1)

1. a preparation method for granatum Chinese yam dispersible tablet, is characterized in that: comprise the following steps:
(1) get after fresh Chinese yam is cleaned and soak 15-20min in the vitamin C aqueous solution of 0.1%, Chinese yam after immersion is put in freeze drier and carries out freeze drying, first open refrigerator to freeze, be chilled to raw material Chinese yam temperature within the scope of-20 to-30 DEG C, and maintain 8-10h drying, then vacuum is opened, and be heated to 95-100 DEG C, continue dry 1-3h, the solid matter that above-mentioned freeze drying obtains is pulverized, obtained Chinese yam freeze-dried powder, for subsequent use;
(2) get the red granatum of raw material, honeysuckle is cleaned, the 4-5 times amount purified water adding above-mentioned raw materials gross weight decocts 2-2.5h within the scope of 90-100 DEG C, filter, the purified water that the dregs of a decoction after filtration add 2-4 times amount is decocted 1-1.5h within the scope of 90-100 DEG C, filter, filter residue is discharged, merge twice filtrate, and carry out being concentrated into the gamma amylase adding 1-2 ‰ when proportion is 1-1.5, at 35-45 DEG C of scope inside holding 5-10h, filter after finally boiling 25-35min, obtain mixed extract, for subsequent use;
(3) be uniformly mixed by gained mixed extract in step (1) gained Chinese yam freeze-dried powder and step (2), mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, Vacuum Concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, Thick many candies, Sucralose, superfine silica gel powder mixing machine mixing make particle, rotating speed is 10-15r/min, time is 6-8min, by mixing after particle 50-60 DEG C of scope inner drying to water content between 1-3%, for subsequent use;
(6) add sodium carboxymethyl starch, dolomol mixing to gained particle in step (5), tabletted, obtains granatum Chinese yam dispersible tablet.
CN201310748589.9A 2013-12-31 2013-12-31 Pomegranate bark and Chinese yam dispersible tablet and preparation method thereof Expired - Fee Related CN103689487B (en)

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CN104757464A (en) * 2015-04-30 2015-07-08 黄馨莹 Haw flake tablet making method
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CN101711824A (en) * 2008-12-06 2010-05-26 孙万群 Chinese medicinal preparation for external use for stopping cough and diarrhea in children
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