CN103656512A - Traditional Chinese medicinal grains for treating cholecystitis and preparation method thereof - Google Patents

Abstract

The invention discloses traditional Chinese medicinal grains for treating cholecystitis and a preparation method thereof. The traditional Chinese medicinal grains are prepared from the following raw materials in parts by weight: 10-15 parts of dried tangerine peel, 5-10 parts of fingered citron, 15-20 parts of Chinese yam, 10-15 parts of endothelium corneum gigeriae galli, 12-18 parts of capillary Artemisia, 8-14 parts of pseudo-ginseng, 5-10 parts of cape jasmine root, 16-22 parts of bupleurum,10-15 parts of scutellaria baicalensis, 7-13 parts of costusroot, 5-10 parts of uncinata spikemoss herb, 10-15 parts of corydalis tuber, 5-10 parts of radix curcumae, 9-16 parts of rhizoma cyperi, 12-18 parts of cortex moutan, 15-20 parts of purple-flower sowthistle, 10-15 parts of red peony root, 10-15 parts of abrus cantoniensis hance, 15-20 parts of rabdosia lophanthide, 10-15 parts of flos gentianae stramienae, 5-10 parts of honeysuckle, 18-24 parts of fructus forsythiae, 12-16 parts of salviae miltiorrhizae, 16-22 parts of peach kernel, 10-15 parts of Chinese angelica, 5-10 parts of Chinese date, 8-14 parts of hawthorn root, and 10-15 parts of dahurian patrinia herb. The traditional Chinese medicinal preparation has the functions of soothing liver-gallbladder, clearing heat and drying dampness, managing qi and activating blood, promoting qi circulation to relieve pain, strengthening the spleen and stomach, and harmonizing and purging, is remarkable in curative effect, exact in drug effect, quick in response and short in course of treatment when used for treating acute and chronic liver-gallbladder, can be used for improving the symptom and relieving pains of a patient, does not have toxic or side effect to a human body, prevents relapse after healing, and is low in treatment cost, convenient to administrate and worthy of popularization and application.

Description

A kind of Chinese medicinal granule for the treatment of cholecystitis and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicinal granule for the treatment of cholecystitis and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Cholecystitis is a kind of more common disease, and sickness rate is higher.Belong to the categories such as Chinese medicine " hypochondriac pain ", " stomachache ", " jaundice ".The traditional Chinese medical science thinks that gallbladder is one of six internal organs, suitable to lead to the behavior of falling, as because of depressed emotion, eating and drinking without temperance, causes QI depression of the liver and gallbladder, and catharsis is not normal, lead to and fall imbalance, produce the symptom of " stagnation of QI and blood may bring about pain ", it is with the pain over the hypochondriac region, gastral cavilty distension, belch is frequent, pantothenic acid is noisy, dry mouth with bitter taste, the tending to vomit of feeling sick, and defecating not well is main manifestations.Along with the progress of gallbladder inflammation, pain also can increase the weight of, and pain presents radioactivity, and modal radiation position is that right shoulder and right inferior angle of scapula etc. are located.The shortcomings such as the Chinese medicine preparation that is used for the treatment of in the market cholecystitis is of a great variety, imprecise but great majority exist drug effect, and curative effect is slow, long, the easy recurrence of healing time.

Summary of the invention

In order to solve the deficiencies in the prior art, the object of the present invention is to provide that a kind of drug effect is definite, evident in efficacy, instant effect, Chinese medicinal granule of short treating period, the treatment cholecystitis that has no side effect, do not recur and preparation method thereof.

For achieving the above object, the present invention adopts following technical scheme:

A kind of Chinese medicinal granule for the treatment of cholecystitis, raw material by following weight portion is made: Pericarpium Citri Reticulatae 10-15, Fructus Citri Sarcodactylis 5-10, Rhizoma Dioscoreae 15-20, Endothelium Corneum Gigeriae Galli 10-15, Herba Artemisiae Scopariae 12-18, Radix Notoginseng 8-14, Fructus Gardeniae root 5-10, Radix Bupleuri 16-22, Radix Scutellariae 10-15, Radix Aucklandiae 7-13, CUIYUNCAO 5-10, Rhizoma Corydalis 10-15, Radix Curcumae 5-10, Rhizoma Cyperi 9-16, Cortex Moutan 12-18, Ixeris denticulata 15-20, Radix Paeoniae Rubra 10-15, Herba Abri 10-15, Herba Rabdosiae Lophanthoidis 15-20, Radix Gentianae Macrophyllae flower 10-15, Flos Lonicerae 5-10, Fructus Forsythiae 18-24, Radix Salviae Miltiorrhizae 12-16, Semen Persicae 16-22, Radix Angelicae Sinensis 10-15, Fructus Jujubae 5-10, Radix Crataegi 8-14, Herba Patriniae 10-15.

Preferably, treat a Chinese medicinal granule for cholecystitis, by the raw material of following weight portion, made: Pericarpium Citri Reticulatae 15, Fructus Citri Sarcodactylis 8, Rhizoma Dioscoreae 20, Endothelium Corneum Gigeriae Galli 12, Herba Artemisiae Scopariae 16, Radix Notoginseng 12, Fructus Gardeniae root 7, Radix Bupleuri 18, Radix Scutellariae 12, the Radix Aucklandiae 11, CUIYUNCAO 8, Rhizoma Corydalis 15, Radix Curcumae 6, Rhizoma Cyperi 13, Cortex Moutan 16, Ixeris denticulata 18, Radix Paeoniae Rubra 15, Herba Abri 10, Herba Rabdosiae Lophanthoidis 18, Radix Gentianae Macrophyllae flower 15, Flos Lonicerae 10, Fructus Forsythiae 22, Radix Salviae Miltiorrhizae 14, Semen Persicae 18, Radix Angelicae Sinensis 10, Fructus Jujubae 10, Radix Crataegi 12, Herba Patriniae 15.

A preparation method for the treatment of the Chinese medicinal granule of cholecystitis, comprises the following steps:

(1) get Fructus Citri Sarcodactylis, Pericarpium Citri Reticulatae, Herba Artemisiae Scopariae, the Radix Aucklandiae, Radix Curcumae, Rhizoma Cyperi, Radix Paeoniae Rubra, Radix Gentianae Macrophyllae flower, Flos Lonicerae mix homogeneously, add the water that 4-6 doubly measures, reflux 1-2h, distillation, collects after first distillate redistillation 0.5-1h, merge distillate, extract volatile oil, standby;

(2) Chinese crude drug mix homogeneously under remainder, decocts with water and extracts 2 times, adds for the first time 5-8 times of water gaging, decoct 2-3h, add for the second time 4-6 times of water gaging, decoct 1-2h, collecting decoction, filters, and it is 1.21-1.25 that filtrate is concentrated into relative density, add ethanol and make to be 50-60%, to stir evenly containing alcohol amount, the standing precipitation that makes, get supernatant, reclaim ethanol and be concentrated into the thick paste that relative density is 1.34-1.38, standby

(3) volatile oil that thick paste step (2) being made and step (1) make stirs, and then adds appropriate sucrose and dextrin, and granulation is dry, obtains.

Usage and consumption: oral, a 4-6g, 2-3 time on the one.

Beneficial effect of the present invention:

Chinese medicine preparation of the present invention is to form with the dialectical compatibility in principle combining based on the differential diagnosis of diseases of Chinese traditional treatment cholecystitis disease, and all medicines share to be played altogether depressed liver-energy dispersing and function of gallbladder promoting, heat clearing and damp drying, vital energy regualting and blood circulation-promoting, promoting the circulation of QI to relieve pain, invigorating the spleen and regulating the stomach, reconciliation and rush down purgation effect, for treatment acute and chronic cholecystitis, has significant curative effect, drug effect is definite, instant effect, short treating period, can improve symptom, alleviate patient suffering, human body is had no side effect, non-relapse after healing, medical expense is low, medication is convenient, is worthy of popularization.

The specific embodiment

Treat a Chinese medicinal granule for cholecystitis, by the raw material of following weight (g), made: Pericarpium Citri Reticulatae 15, Fructus Citri Sarcodactylis 8, Rhizoma Dioscoreae 20, Endothelium Corneum Gigeriae Galli 12, Herba Artemisiae Scopariae 16, Radix Notoginseng 12, Fructus Gardeniae root 7, Radix Bupleuri 18, Radix Scutellariae 12, the Radix Aucklandiae 11, CUIYUNCAO 8, Rhizoma Corydalis 15, Radix Curcumae 6, Rhizoma Cyperi 13, Cortex Moutan 16, Ixeris denticulata 18, Radix Paeoniae Rubra 15, Herba Abri 10, Herba Rabdosiae Lophanthoidis 18, Radix Gentianae Macrophyllae flower 15, Flos Lonicerae 10, Fructus Forsythiae 22, Radix Salviae Miltiorrhizae 14, Semen Persicae 18, Radix Angelicae Sinensis 10, Fructus Jujubae 10, Radix Crataegi 12, Herba Patriniae 15.

A preparation method for the treatment of the Chinese medicinal granule of cholecystitis, comprises the following steps:

(1) get Fructus Citri Sarcodactylis, Pericarpium Citri Reticulatae, Herba Artemisiae Scopariae, the Radix Aucklandiae, Radix Curcumae, Rhizoma Cyperi, Radix Paeoniae Rubra, Radix Gentianae Macrophyllae flower, Flos Lonicerae mix homogeneously, add the water of 5 times of amounts, reflux 1h,, distillation, collects after first distillate, and redistillation 0.5h, merges distillate, extracts volatile oil, standby;

(2) Chinese crude drug mix homogeneously under remainder, decocts with water and extracts 2 times, adds for the first time 7 times of water gagings, decoct 2h, add for the second time 5 times of water gagings, decoct 1h, collecting decoction, filters, and it is 1.23 that filtrate is concentrated into relative density, add ethanol and make to be 60%, to stir evenly containing alcohol amount, the standing precipitation that makes, get supernatant, reclaiming ethanol and being concentrated into relative density is 1.36 thick paste, standby

(3) volatile oil that thick paste step (2) being made and step (1) make stirs, and then adds appropriate sucrose and dextrin, and granulation is dry, obtains.

Usage and consumption: oral, a 4-6g, 2-3 time on the one.

Model case:

Case 1: Cao, female, 45 years old.Pain in the right hypochondrium 6 years, increases the weight of first quarter moon.Before 6 years, there is first pain in the right hypochondrium symptom in patient, accompany nausea and vomiting simultaneously, in local hospital inspection, be diagnosed as cholecystitis, through using antibiotic and pain management, remission, but hereafter, at least show effect every year more than 3 times, the meat of dare not taking food, the diet such as egg, mostly the inducement of each recurrence is that feelings will is unsuccessful, before first quarter moon, patient's family is unfortunate stolen, suffer heavy losses, thereby melancholy joyless, cholecystitis recurrence immediately, through antibiotic therapy 10 days, has no effect, there is jaundice simultaneously, then seek medical advice in here, see that patient body is thin, expression is painful, anorexia, nauseating nausea, bitter taste, dry stool, right flank gallbladder district pain with tenderness, it is heavy when time is light, B ultrasonic shows that gallbladder increases, wall is crude, remaining without abnormal, red tongue with yellow fur is thick, stringy pulse.Give Granules in Treating of the present invention.Take medicine after 12 days, right flank pain relief, diet takes a turn for the better, and nausea and vomiting disappears, and continues to take medicine after 8 days, and all diseases disappear, and spirit, diet recover normal, recovery from illness.Follow up a case by regular visits to not recurrence so far.

Case 2: Deng, female, 66 years old.Right flank portion dull pain, fever with aversion to cold one week.Patient's private prosecution aversion to cold that began to occur before a week, heating, right flank portion pain, distending pain is main, is radiated to upper right abdomen, companion's nausea and vomiting, vomiting gastric content, body temperature be take and in the afternoon raise as main, is up to 38.6 ℃.Sweating after clothes " analgesic powder ", heat is moved back.Rise again Relapse rate outbreak thereupon.Then here is medical.Disease is seen: right flank portion dull pain, and poor appetite, bitter taste, yellow urine, constipation with dry stool, without aversion to cold, heating.B ultrasonic shows: weary property calculus in gallbladder, choledochectasia, right cyst of kidney.Be diagnosed as: cholecystitis, cholelithiasis.Give Granules in Treating of the present invention.Take medicine after 10 days, right flank portion dull pain alleviates, and without nausea and vomiting, body temperature is normal, and two just adjust, and continue to take medicine after 15 days, and dull pain disappears, and without malaise symptoms, in ultrasound diagnosis gallbladder, without calculus, fully recovers.Follow up a case by regular visits to not recurrence so far.

Case 3: Zhang, man, 28 years old.Suffer from cholecystitis 2 years, without cholelithiasis.You Lei district is dull pain 1 month repeatedly, increases the weight of today and have tenderness in gallbladder area, and here is medical then.Disease is seen: there is tenderness sense in You Lei district, and without fear of cold heating, xerostomia is bitter, and thirst and liking cold drink, sleep poor, cardiopalmus once in a while, dimly red tongue, the slightly thick a little Huang of tongue, left guan string.Give Granules in Treating of the present invention.Take medicine after 8 days, pain relief, body temperature is normal, and sleep takes a turn for the better, and continues to take medicine after 10 days, and pain disappears, and sleep is normal, without malaise symptoms, recovery from illness.Follow up a case by regular visits to not recurrence so far.

Claims (3)

1. a Chinese medicinal granule for the treatment of cholecystitis, it is characterized in that, raw material by following weight portion is made: Pericarpium Citri Reticulatae 10-15, Fructus Citri Sarcodactylis 5-10, Rhizoma Dioscoreae 15-20, Endothelium Corneum Gigeriae Galli 10-15, Herba Artemisiae Scopariae 12-18, Radix Notoginseng 8-14, Fructus Gardeniae root 5-10, Radix Bupleuri 16-22, Radix Scutellariae 10-15, Radix Aucklandiae 7-13, CUIYUNCAO 5-10, Rhizoma Corydalis 10-15, Radix Curcumae 5-10, Rhizoma Cyperi 9-16, Cortex Moutan 12-18, Ixeris denticulata 15-20, Radix Paeoniae Rubra 10-15, Herba Abri 10-15, Herba Rabdosiae Lophanthoidis 15-20, Radix Gentianae Macrophyllae flower 10-15, Flos Lonicerae 5-10, Fructus Forsythiae 18-24, Radix Salviae Miltiorrhizae 12-16, Semen Persicae 16-22, Radix Angelicae Sinensis 10-15, Fructus Jujubae 5-10, Radix Crataegi 8-14, Herba Patriniae 10-15.

2. a kind of Chinese medicinal granule for the treatment of cholecystitis according to claim 1, it is characterized in that, by the raw material of following weight portion, made: Pericarpium Citri Reticulatae 15, Fructus Citri Sarcodactylis 8, Rhizoma Dioscoreae 20, Endothelium Corneum Gigeriae Galli 12, Herba Artemisiae Scopariae 16, Radix Notoginseng 12, Fructus Gardeniae root 7, Radix Bupleuri 18, Radix Scutellariae 12, the Radix Aucklandiae 11, CUIYUNCAO 8, Rhizoma Corydalis 15, Radix Curcumae 6, Rhizoma Cyperi 13, Cortex Moutan 16, Ixeris denticulata 18, Radix Paeoniae Rubra 15, Herba Abri 10, Herba Rabdosiae Lophanthoidis 18, Radix Gentianae Macrophyllae flower 15, Flos Lonicerae 10, Fructus Forsythiae 22, Radix Salviae Miltiorrhizae 14, Semen Persicae 18, Radix Angelicae Sinensis 10, Fructus Jujubae 10, Radix Crataegi 12, Herba Patriniae 15.

3. a preparation method for the Chinese medicinal granule for the treatment of cholecystitis as claimed in claim 1 or 2, is characterized in that comprising the following steps:

Get Fructus Citri Sarcodactylis, Pericarpium Citri Reticulatae, Herba Artemisiae Scopariae, the Radix Aucklandiae, Radix Curcumae, Rhizoma Cyperi, Radix Paeoniae Rubra, Radix Gentianae Macrophyllae flower, Flos Lonicerae mix homogeneously, add the water that 4-6 doubly measures, reflux 1-2h,, distillation, collects after first distillate, and redistillation 0.5-1h, merges distillate, extracts volatile oil, standby;

(2) Chinese crude drug mix homogeneously under remainder, decocts with water and extracts 2 times, adds for the first time 5-8 times of water gaging, decoct 2-3h, add for the second time 4-6 times of water gaging, decoct 1-2h, collecting decoction, filters, and it is 1.21-1.25 that filtrate is concentrated into relative density, add ethanol and make to be 50-60%, to stir evenly containing alcohol amount, the standing precipitation that makes, get supernatant, reclaim ethanol and be concentrated into the thick paste that relative density is 1.34-1.38, standby

(3) volatile oil that thick paste step (2) being made and step (1) make stirs, and then adds appropriate sucrose and dextrin, and granulation is dry, obtains.