CN102697878B - Radix puerariae traditional Chinese medicine preparation for treating rheumatic arthritis and preparation method for preparation - Google Patents

Radix puerariae traditional Chinese medicine preparation for treating rheumatic arthritis and preparation method for preparation Download PDF

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CN102697878B
CN102697878B CN 201210208567 CN201210208567A CN102697878B CN 102697878 B CN102697878 B CN 102697878B CN 201210208567 CN201210208567 CN 201210208567 CN 201210208567 A CN201210208567 A CN 201210208567A CN 102697878 B CN102697878 B CN 102697878B
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CN102697878A (en
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陈慧婷
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Guangzhou Jindian Jingfang Pharmaceutical Co., Ltd.
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陈慧婷
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Abstract

The invention discloses a radix puerariae traditional Chinese medicine preparation for treating rheumatic arthritis. The radix puerariae traditional Chinese medicine preparation for treating the rheumatic arthritis is prepared from the following traditional Chinese medicine raw materials in parts by weight: 400-800 parts of radix puerariae, 250-650 parts of caulis lonicerae, 100-200 parts of radix stephaniae tetrandrae, 100-200 parts of fructus forsythia, 100-200 parts of felwort, 50-150 parts of angelica sinensis, 50-150 parts of red paeonia and 50-150 parts of ligusticum wallichii. The traditional Chinese medicines jointly take effect of clearing heat and dredging collaterals and dispelling wind and eliminating dampness. The traditional Chinese medicine preparation disclosed by the invention is obvious in treatment effect on rheumatic arthralgia-type rheumatic arthritis patients, and can be used for rapidly relieving arthralgia, local scorching redness and swelling, slight comfort after getting cool and untouchable pain and the symptom with one or more than one diseased joint and with fever, aversion to wind, thirst and dysphoria. The preparation has no toxic and side effects and is obvious in treatment effect, and the pains of patients are fundamentally relieved.

Description

Radix Puerariae Chinese medicine preparation and the preparation method for the treatment of rheumatic arthritis
Technical field
The invention belongs to the field of Chinese medicines, relate in particular to a kind of Radix Puerariae Chinese medicine preparation and preparation method that is used for the treatment of rheumatic arthritis.
Background technology
Rheumatic arthritis is kind of a common chronic disease, there is 90% people to suffer from osteoarthritis among the domestic over-65s crowd, the severe patient life-span shortens 10-15 approximately. and visible its extent of injury wind, wet arthritis (rheumatoid arthritis) is a kind of common acute or chronic ICT.Can show effect repeatedly and involve heart.Clinical miserable with joint and muscle migration, heavily work, pain is feature.Belong to allergic disease.Be one of main performance of rheumatic fever, how with febris acuta and arthralgia onset.Typical case's performance of rheumatic arthritis is slight or the moderate heating, migratory polyarthritis, the joint of getting involved mostly is big joint such as knee joint, ankle, shoulder, elbow wrist, commonly be transferred to another joint by a joint; the pathological changes part presents redness, scorching hot, severe pain part patient also has several joints to fall ill simultaneously; atypical patient only has arthralgia and do not have other inflammation performances, and acute inflammation generally disappears in 2-4 week and do not stay sequela, but the Chang Fanfu outbreak.If active rheumatism influences heart and myocarditis then can take place even leave over valve disorder.Rheumatic arthritis is common clinical, frequently-occurring disease, does not still have specific short at present.Western medicine expenses for medicine height, side effect is big, also recurrence easily.Adopt the means of Chinese medicine to treat the rheumatic arthritis disease, be a channel extremely leaved for development, applied widely, there is its original effect the treatment aspect.
Summary of the invention
Purpose of the present invention is exactly in order to overcome the above-mentioned defective of prior art, a kind of advantages of perfect compatibility that has to be provided, have no side effect, and curative effect is treated Radix Puerariae Chinese medicine preparation and the preparation method of rheumatic arthritis reliably.
The Radix Puerariae Chinese medicine preparation for the treatment of rheumatic arthritis, made by following parts by weight of Chinese traditional medicine raw material:
Radix Puerariae 400-800 part, Caulis Lonicerae 250-650 part, Radix Stephaniae Tetrandrae 100-200 part, Fructus Forsythiae 100-200 part, Radix Gentianae 100-200 part, Radix Angelicae Sinensis 50-150 part, Radix Paeoniae Rubra 50-150 part, Rhizoma Chuanxiong 50-150 part.
The Radix Puerariae Chinese medicine preparation of described treatment rheumatic arthritis, made by following parts by weight of Chinese traditional medicine raw material:
600 parts of Radix Puerariaes, 450 parts of Caulis Loniceraes, 150 parts of Radixs Stephaniae Tetrandrae, 150 parts of Fructus Forsythiaes, 150 parts of Radix Gentianaes, 100 parts of Radix Angelicae Sinensis, 100 parts of Radix Paeoniae Rubra, 100 parts of Rhizoma Chuanxiongs.
The preparation method of the Radix Puerariae Chinese medicine preparation of described treatment rheumatic arthritis, its preparation method is:
Take by weighing 600 parts of above-mentioned raw material of Chinese medicine Radix Puerariaes, 450 parts of Caulis Loniceraes, 150 parts of Radixs Stephaniae Tetrandrae, 150 parts of Fructus Forsythiaes, 150 parts of Radix Gentianaes, 100 parts of Radix Angelicae Sinensis, 100 parts of Radix Paeoniae Rubra, 100 parts of Rhizoma Chuanxiongs in proportion, cleaning is dried, be ground into granule, soaked 1.5 hours, decoct with water twice then, add the water of 8 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add the water of 6 times of amounts of crude drug for the second time, decocted 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, packing namely.
Usage and consumption: oral Chinese medicine preparation of the present invention, each 180ml, every day 2 times, after meal half an hour, 1 month is 1 course for the treatment of.
The pharmacological action of crude drug of the present invention is as follows, Radix Puerariae: sweet, hot, cool, attach to the lung and stomach meridians relieving muscles diaphoresis, rash, yang invigorating antidiarrheal, promoting the production of body fluid to quench thirst; Caulis Lonicerae: cold, sweet, go into lung meridian, stomach warp, heat-clearing and toxic substances removing, dispelling wind collateral dredging; Radix Stephaniae Tetrandrae: bitter, hot, cold, return bladder, kidney, spleen channel, wind-damp dispelling, pain relieving, diuretic; Fructus Forsythiae: be slightly cold bitter in the mouth; Go into lung meridian, heart channel, gallbladder meridian, Liver Channel, Radix Gentianae: bitter, cold, return liver, gallbladder meridian, heat clearing and damp drying, removing fire from the liver; Radix Angelicae Sinensis: sweet, hot, warm, return liver, the heart, spleen channel, promoting blood circulation and stopping pain, tonifying blood and regulating menstruation, loosening bowel to relieve constipation; Radix Paeoniae Rubra: bitter, be slightly cold, return Liver Channel, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, pain relieving; Rhizoma Chuanxiong: hot, warm, return liver, gallbladder, pericardium channel, blood-activating and qi-promoting, wind-expelling pain-stopping; All medicines are played the merit of heat clearing away collateral dredging, expelling wind and removing dampness altogether, Chinese medicine preparation of the present invention has remarkable therapeutic effect to rheumatism pyretic arthralgia type rheumatic arthritis patient, can alleviate arthralgia rapidly, local scorching hot redness gets cold easypro slightly, pain can not be touched, can sick and one or more joints, have the symptom of heating, aversion to wind, thirsty, restlessness with opprssive feeling and worry concurrently, this preparation has no side effect, therapeutic effect is remarkable, has fundamentally removed patient's misery.
The specific embodiment
EXAMPLE l:
Raw material of Chinese medicine: 600 parts of Radix Puerariaes, 450 parts of Caulis Loniceraes, 150 parts of Radixs Stephaniae Tetrandrae, 150 parts of Fructus Forsythiaes, 150 parts of Radix Gentianaes, 100 parts of Radix Angelicae Sinensis, 100 parts of Radix Paeoniae Rubra, 100 parts of Rhizoma Chuanxiongs.
Preparation method: take by weighing 600 parts of above-mentioned raw material of Chinese medicine Radix Puerariaes, 450 parts of Caulis Loniceraes, 150 parts of Radixs Stephaniae Tetrandrae, 150 parts of Fructus Forsythiaes, 150 parts of Radix Gentianaes, 100 parts of Radix Angelicae Sinensis, 100 parts of Radix Paeoniae Rubra, 100 parts of Rhizoma Chuanxiongs in proportion, cleaning is dried, be ground into granule, soaked 1.5 hours, decoct with water twice then, add the water of 8 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add the water of 6 times of amounts of crude drug for the second time, decocted 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, packing namely.
Usage and consumption: oral Chinese medicine preparation of the present invention, each 180ml, every day 2 times, after meal half an hour, 1 month is 1 course for the treatment of.
Embodiment 2
Raw material of Chinese medicine: 800 parts of Radix Puerariaes, 650 parts of Caulis Loniceraes, 200 parts of Radixs Stephaniae Tetrandrae, 200 parts of Fructus Forsythiaes, 200 parts of Radix Gentianaes, 150 parts of Radix Angelicae Sinensis, 150 parts of Radix Paeoniae Rubra, 150 parts of Rhizoma Chuanxiongs.
Preparation method: take by weighing 800 parts of above-mentioned raw material of Chinese medicine Radix Puerariaes, 650 parts of Caulis Loniceraes, 200 parts of Radixs Stephaniae Tetrandrae, 200 parts of Fructus Forsythiaes, 200 parts of Radix Gentianaes, 150 parts of Radix Angelicae Sinensis, 150 parts of Radix Paeoniae Rubra, 150 parts of Rhizoma Chuanxiongs in proportion, cleaning is dried, be ground into granule, soaked 1.5 hours, decoct with water twice then, add the water of 8 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add the water of 6 times of amounts of crude drug for the second time, decocted 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, packing namely.
Usage and consumption: oral Chinese medicine preparation of the present invention, each 180ml, every day 2 times, after meal half an hour, 1 month is 1 course for the treatment of.
Embodiment 3:
Raw material of Chinese medicine: 400 parts of Radix Puerariaes, 250 parts of Caulis Loniceraes, 100 parts of Radixs Stephaniae Tetrandrae, 100 parts of Fructus Forsythiaes, 100 parts of Radix Gentianaes, 50 parts of Radix Angelicae Sinensis, 50 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs.
Preparation method: take by weighing 400 parts of above-mentioned raw material of Chinese medicine Radix Puerariaes, 250 parts of Caulis Loniceraes, 100 parts of Radixs Stephaniae Tetrandrae, 100 parts of Fructus Forsythiaes, 100 parts of Radix Gentianaes, 50 parts of Radix Angelicae Sinensis, 50 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs in proportion, cleaning is dried, be ground into granule, soaked 1.5 hours, decoct with water twice then, add the water of 8 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add the water of 6 times of amounts of crude drug for the second time, decocted 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, packing namely.
Usage and consumption: oral Chinese medicine preparation of the present invention, each 180ml, every day 2 times, after meal half an hour, 1 month is 1 course for the treatment of.
Embodiment 4:
Clinical trial:
1) physical data: carry out clinical observation treatment at 35 routine rheumatism pyretic arthralgia type rheumatic arthritis patients, the age 50, course of disease 1-8 did not wait by 80 years old.
2) diagnostic criteria: primary symptom: arthralgia, local scorching hot redness gets cold easyproly slightly, and pain can not be touched, can sick and one or more joint, have heating, aversion to wind, thirsty, restlessness with opprssive feeling and worry concurrently, yellow and greasy fur, slippery and rapid pulse more.
3) Therapeutic Method: the oral embodiment of the invention 1 Chinese medicine preparation, each 180ml, every day 2 times, after meal half an hour, 1 month is 1 course for the treatment of.
4) efficacy assessment standard:
Cure in the recent period: the arthralgia of getting involved disappears, and joint function recovery is normal, and the clinical symptoms sign disappears, and recovers normal.
Produce effects: the arthralgia of getting involved is clearly better or disappears, basic or most of disappearance of clinical symptoms sign.
Effectively: the arthralgia or swell and ache and take a favorable turn of getting involved after treatment, clinical symptoms is clearly better.
Invalid: the clinical symptoms sign does not have improvement.
5) therapeutic effect: 35 routine rheumatism pyretic arthralgia type rheumatic arthritis patients cure 3-6 courses for the treatment of in the recent period, cure 28 examples in the recent period; Produce effects 5 examples, effective 2 examples, invalid 0 example, total effective rate 100%.
Embodiment 5:
Model case: together certain, the woman 63 years old, suffers from rheumatic arthritis, arthralgia, local scorching hot redness gets cold easypro slightly, pain can not be touched a plurality of arthralgias, heating, aversion to wind, thirsty, restlessness with opprssive feeling and worry, yellow and greasy fur, slippery and rapid pulse, the oral embodiment of the invention 1 Chinese medicine preparation, each 180ml, every day 2 times, half an hour after meal, 1 month is 1 course for the treatment of, and take effect 1 course for the treatment of, and cure 6 courses for the treatment of in the recent period.
Embodiment 6:
Model case: field, woman, 59 years old, suffer from rheumatic arthritis, local scorching hot redness gets cold easypro slightly, pain can not be touched a plurality of arthralgias, heating, aversion to wind, thirsty, restlessness with opprssive feeling and worry, yellow and greasy fur, slippery and rapid pulse, the oral embodiment of the invention 1 Chinese medicine preparation, each 180ml, every day 2 times, half an hour after meal, 1 month is 1 course for the treatment of, and take effect 1 course for the treatment of, and cure 5 courses for the treatment of in the recent period.
Embodiment 7:
Model case: Wu, man, 71 years old, suffer from rheumatic arthritis, local scorching hot redness gets cold easypro slightly, pain can not be touched a plurality of arthralgias, aversion to wind, thirsty, restlessness with opprssive feeling and worry, yellow and greasy fur, slippery and rapid pulse, the oral embodiment of the invention 1 Chinese medicine preparation, each 180ml, every day 2 times, half an hour after meal, 1 month is 1 course for the treatment of, and take effect 1 course for the treatment of, and cure 6 courses for the treatment of in the recent period.

Claims (1)

1. treat the Radix Puerariae Chinese medicine preparation of rheumatic arthritis, it is characterized in that: made by following parts by weight of Chinese traditional medicine raw material:
600 parts of Radix Puerariaes, 450 parts of Caulis Loniceraes, 150 parts of Radixs Stephaniae Tetrandrae, 150 parts of Fructus Forsythiaes, 150 parts of Radix Gentianaes, 100 parts of Radix Angelicae Sinensis, 100 parts of Radix Paeoniae Rubra, 100 parts of Rhizoma Chuanxiongs; Its preparation process is:
Take by weighing 600 parts of above-mentioned raw material of Chinese medicine Radix Puerariaes, 450 parts of Caulis Loniceraes, 150 parts of Radixs Stephaniae Tetrandrae, 150 parts of Fructus Forsythiaes, 150 parts of Radix Gentianaes, 100 parts of Radix Angelicae Sinensis, 100 parts of Radix Paeoniae Rubra, 100 parts of Rhizoma Chuanxiongs in proportion, cleaning is dried, be ground into granule, soaked 1.5 hours, decoct with water twice then, add the water of 8 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add the water of 6 times of amounts of crude drug for the second time, decocted 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, packing namely.
CN 201210208567 2012-06-21 2012-06-21 Radix puerariae traditional Chinese medicine preparation for treating rheumatic arthritis and preparation method for preparation Active CN102697878B (en)

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CN103083433B (en) * 2013-01-24 2015-06-17 贵州大龙健康油脂有限公司 Drug for treating rheumatism and rheumatoid sciatica
CN104435900A (en) * 2015-01-06 2015-03-25 王国徽 Medicine for treating rheumatic arthritis and preparation method

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