CN103656370A - Medicine for treating medium-term diabetic nephropathy - Google Patents
Medicine for treating medium-term diabetic nephropathy Download PDFInfo
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- CN103656370A CN103656370A CN201210367580.9A CN201210367580A CN103656370A CN 103656370 A CN103656370 A CN 103656370A CN 201210367580 A CN201210367580 A CN 201210367580A CN 103656370 A CN103656370 A CN 103656370A
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Abstract
The invention relates to a medicine for treating medium-term diabetic nephropathy, belonging to the technical field of traditional Chinese medicine preparations. The medicine is mainly prepared from 16 active pharmaceutical ingredients, including ginseng, radix astragali, wolf's bane, cinnamon, hirudo, motherwort, corn silk, orientvine, tuckahoe, rhizoma alismatis, mulberry and the like. The medicine is prepared into capsules, tablets, pills, granules, oral liquids and other preparation formulations by pharmaceutical instruments. The medicine has the functions of warming the kidney, strengthening the spleen, promoting blood circulation, dredging collaterals and inducing diuresis to alleviate edema, has definite curative effect on medium-term diabetic nephropathy, and has no toxic or side effect.
Description
Technical field
The invention belongs to Chinese medicine preparation technical field.
Background technology
Diabetic nephropathy is one of diabetes severe complication, is also one of diabetics major causes of death.Diabetic nephropathy generally have initial stage, mid-term, (edema is early stage) and late period (Uremic) three phases, if patient has arrived the nephropathy mid-term of diabetes, all because of deficiency of spleen-YANG and kidneyYANG, retention of water-damp in the body, the state of an illness is more serious, if not actively effectively treatment, can develop into late period is diabetic nephropathy Uremic, and consequence is just very serious.For diabetic nephropathy, modern medicine, except controlling the Primary Cares such as blood glucose blood pressure, does not have specially good effect measure.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of new medicine of controlling interim period diabetic nephropathy (edema is early stage) is provided.The present invention has warming the kidney and strengthening the spleen, promoting blood circulation to remove obstruction in the collateral, the effect of inducing diuresis to remove edema.Can reach determined curative effect, have no side effect, take easy object.
The technical solution adopted for the present invention to solve the technical problems is: Radix Ginseng, the Radix Astragali, Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Hirudo, Pheretima, Herba Leonuri, Poria, Polyporus, Rhizoma Alismatis, Stigma Maydis, Herba Cistanches, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Rhizoma Imperatae, 16 kinds of crude drug of Fructus Mori, consist of.
In preparation of the present invention about pharmaceutical compositions major function and configuration:
Radix Ginseng in the present invention, nature and flavor are sweet, bitter, tepor.Containing ginsenoside, volatile oil, panax acid, glycocide etc.Invigorating QI to relieve exhaustion, promoting the production of body fluid and inducing sedation of the mind.Cure mainly vigour weakness, inappetence, cold extremities due to sweating, deficiency of body fluid, the deficiency of the lung is breathed with cough, and palpitation with fear is strong absurd.
The Radix Astragali in the present invention, nature and flavor are sweet, tepor.Containing choline, betanin, folic acid, aminoacid, saccharide etc.QI invigorating is returned table, promoting pus discharge and tissue regeneration strengthening.Cure mainly exterior deficiency spontaneous perspiration, night sweat, deficiency of vital energy blood prostration, diarrhea due to hypofunction of the spleen, carbuncle is not burst or is burst and do not restrain, and the disease of all insufficiency of primordial QI.
Radix Aconiti Lateralis Preparata in the present invention, nature and flavor are pungent, hot greatly, poisonous.Containing aconitine, hypaconitine, lipid component etc.Recuperating depleted YANG, warming the interior is by cold, pain relieving.Cure mainly YANG-depletion collapse, extreme cold of the limbs, sweating faint pulse, deficiency and coldness is had loose bowels, coldness and pain in the epigastrium, arthralgia due to cold-dampnes, deficiency of YIN edema, heart failure, oedema due to chronic nephritis.
Cortex Cinnamomi in the present invention, nature and flavor are pungent, sweet, hot greatly.Containing volatile oil, phlegmatic temperament, tannic acid and resin etc.Warming middle-JIAO, cold expelling, pain relieving.Fire is not enough mutually to cure mainly the gate of vitality, cold extremities faint pulse, and cold syndrome of the stomach stomachache is vomited and diarrhoea, chills and pain of the waist and kness, carbuncle of yin nature hernia abdominal mass, upward floating of YANG in deficiency condition, heat in the upper and cold in the lower.
Hirudo in the present invention, nature and flavor become, and hardship is flat, poisonous.Containing protein, hirudin, heparin, antithromboxin etc.Removing blood stasis, the stasis of blood, stimulates the menstrual flow then.Cure mainly women's amenorrhea, blood-stasis internal-depression, lump in the abdomen, traumatic injury, conjunctival congestion is swollen, nebula.
Pheretima in the present invention, nature and flavor are salty, cold.Containing lumbricin, succinic acid, cholesterol, fatty acid, choline etc.Heat clearing away, spasmolytic, Dingchuan, blood pressure lowering, diuresis, removing toxic substances.Cure mainly calentura mania and irritation, infantile convulsion, cough with asthma, headache conjunctival congestion, swelling and sore throat, urinary obstruction, Fengshi Guanjie pain, the diseases such as hemiplegia.
Herba Leonuri in the present invention, nature and flavor are pungent, and hardship is cold.Containing leonurine, stachydrine, Saponin, sterol, organic acid, saccharide, phenolic substance etc.Promoting tissue regeneration by removing blood stasis, the regulating menstruation water that disappears.Cure mainly menoxenia, vaginal bleeding during pregnancy difficult labour, afterbirth not just, postnatal blood stasis, stomachache lump in the abdomen, dysuria, edema.
Poria in the present invention, nature and flavor are sweet, light, flat.Containing pachymic acid, ergosterol, choline, histidine, protein, lecithin, fat etc.Eliminating dampness and diuresis, tranquilizing mind, strengthening the spleen stomach.Cure mainly spleen-asthenia with excessive damp, edema distension, phlegm retention cough with dyspnea, dirty the having loose bowels of vomitting, dysuria.
Polyporus in the present invention, nature and flavor are sweet, flat.Containing ergosterol, polysaccharide compound, protein.Eliminating dampness and diuresis.Cure mainly edema distension, stranguria with turbid discharge beriberi, dysuria.
Rhizoma Alismatis in the present invention, nature and flavor are sweet, are slightly cold.Containing triterpenoid compound, volatile oil, alkaloid, saccharide, asparagine, plant sterol, resin etc.Eliminating dampness by diuresis, diuresis.Cure mainly damp-heat in the urinary bladder, dysuria, edema distension, dysentery, stranguria with turbid discharge.
Stigma Maydis in the present invention, nature and flavor are sweet, light, flat.Diuresis expels the heat-evil, suppressing the hyperactive liver, function of gallbladder promoting.Cure mainly oedema due to nephritis, beriberi, icterohepatitis, hypertension, cholecystitis, spits blood, epistaxis, mastalgia, diabetes.
Herba Cistanches in the present invention, nature and flavor are sweet, and acid becomes tepor.Containing mannitol, alkaloid and crystallinity neutral substance.Mend the gate of vitality, benefiting essence-blood, laxation.Cure mainly impotence in male, infertilitas feminis, chills and pain of the waist and kness, blood depletion constipation.
Radix Stephaniae Tetrandrae in the present invention, nature and flavor are bitter, cold.Containing alkaloid, volatile oil, starch etc.Dispel the wind, row water.Cure mainly edema, hygropyretic beriberi, brothers' spasm and pain.
Rhizoma Smilacis Glabrae in the present invention, nature and flavor are sweet, light, flat.Containing multiple steroid saponin, alkaloid, volatile oil, saccharide, resin, starch etc.Dampness removing, removing toxic substances.Cure mainly Fructus Myricae rubrae skin infection, muscles and bones spasm and pain, scrofula carbuncle, antimercurialism.
Rhizoma Imperatae in the present invention, nature and flavor are sweet, cold.Containing mannitol, glucose, fructose, sucrose, citric acid, malic acid, potassium chloride, Cylindrin, organic acid etc.Clearing away heat and cooling blood, relieving stranguria by diuresis.Cure mainly interior-heat excessive thirst, hematemesis and epistaxis, dysuria, pyretic stranguria hematuria.
Fructus Mori in the present invention, nature and flavor are sweet, acid, temperature.Containing carotene, vitamin C, nicotinic acid, glucose, pectin, tannin, calcareous, inorganic salt etc.Invigorating the liver and kidney, nourishing blood for improving eyesight, promoting the production of body fluid to quench thirst.Cure mainly blood deficiency, deafness, dizzy, quench one's thirst, scrofula.
Mid-term diabetic nephropathy patient all because of deficiency of qi and yin day very, deficiency of YIN affecting YANG, deficiency of spleen-YANG and kidneyYANG, sun is activating QI not, raw in water is wet, common fatigue and weakness, aversion to cold and cold limbs, gastral cavity abdominal distention is vexed, indigestion and loss of appetite loose stool or see face and the symptom such as the slight edema of lower limb.The present invention has warming the kidney and strengthening the spleen, promoting blood circulation to remove obstruction in the collateral, and the effect of inducing diuresis to remove edema, therefore centering period diabetic nephropathy has good curative effect.The invention has the beneficial effects as follows: through clinical practice proof centering period diabetic nephropathy determined curative effect, have no side effect, take easy.
The specific embodiment
1, formula and part by weight: 12 parts of Radix Ginsengs, 30 parts of the Radixs Astragali, 12 parts of Radix Aconiti Lateralis Preparatas, 15 parts of Cortex Cinnamomis, 18 parts of Hirudos, 12 parts of Pheretimas, 30 parts of Herba Leonuris, 15 parts of Polyporus, 20 parts, Poria, 18 parts of Rhizoma Alismatis, 20 parts of Stigma Maydis, 18 parts of Herba Cistanches, 20 parts, Fructus Mori, 15 parts of Radixs Stephaniae Tetrandrae, 15 parts of Rhizoma Smilacis Glabraes, 25 parts of Rhizoma Imperataes.
2, manufacture method: above-mentioned 16 kinds of crude drug are weighed and assorted in proportion, and it is qualified to concoct with pharmaceutical equipment apparatus, purifies, and concentrated, mix homogeneously post-treatment becomes capsule, and the different dosage forms such as tablet, pill, granule, oral liquid are standby.
Claims (1)
1. treat a medicine for middle period diabetic nephropathy, it is characterized in that crude drug formula and part by weight are 12 parts of Radix Ginsengs, 30 parts of the Radixs Astragali, 12 parts of Radix Aconiti Lateralis Preparatas, 15 parts of Cortex Cinnamomis, 18 parts of Hirudos, 12 parts of Pheretimas, 30 parts of Herba Leonuris, 20 parts, Poria, 15 parts of Polyporus, 18 parts of Rhizoma Alismatis, 20 parts of Stigma Maydis, 18 parts of Herba Cistanches, 20 parts, Fructus Mori, 15 parts of Radixs Stephaniae Tetrandrae, 15 parts of Rhizoma Smilacis Glabraes, 25 parts of Rhizoma Imperataes; Above-mentioned raw materials medicine is weighed and is assorted in proportion, with pharmaceutical equipment apparatus concoct qualified, purify, concentrated, mix homogeneously post-treatment becomes capsule, tablet, pill, granule, oral liquid different dosage form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210367580.9A CN103656370A (en) | 2012-09-14 | 2012-09-14 | Medicine for treating medium-term diabetic nephropathy |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210367580.9A CN103656370A (en) | 2012-09-14 | 2012-09-14 | Medicine for treating medium-term diabetic nephropathy |
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| CN103656370A true CN103656370A (en) | 2014-03-26 |
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| CN201210367580.9A Pending CN103656370A (en) | 2012-09-14 | 2012-09-14 | Medicine for treating medium-term diabetic nephropathy |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311470A (en) * | 2015-11-18 | 2016-02-10 | 暨南大学 | Application of pharmaceutical composition containing folium artemisiae argyi in preparing medicine for treating diabetic nephropathy |
-
2012
- 2012-09-14 CN CN201210367580.9A patent/CN103656370A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311470A (en) * | 2015-11-18 | 2016-02-10 | 暨南大学 | Application of pharmaceutical composition containing folium artemisiae argyi in preparing medicine for treating diabetic nephropathy |
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Application publication date: 20140326 |