CN103656294A - Medicine for treating acute glomerulonephritis and preparation method thereof - Google Patents

Medicine for treating acute glomerulonephritis and preparation method thereof Download PDF

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CN103656294A
CN103656294A CN201310677457.1A CN201310677457A CN103656294A CN 103656294 A CN103656294 A CN 103656294A CN 201310677457 A CN201310677457 A CN 201310677457A CN 103656294 A CN103656294 A CN 103656294A
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CN103656294B (en
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徐士魁
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Abstract

The invention discloses a medicine for treating acute glomerulonephritis and a preparation method thereof. The medicine is mainly prepared from fructus rosae laevigatae, oldenlandia, wrinkled giant hyssop, pomegranate bark, senstive plant root, motherwort, areca peel, common cephalanoplos herb, flos sophorae and the like in a certain weight ratio. The medicine has the functions of clearing heat and removing toxicity, and inducing diuresis and reducing edema, and is quick in response and high in cure rate when used for treating acute glomerulonephritis.

Description

A kind of medicine for the treatment of acute glomerulonephritis of baby and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of acute glomerulonephritis of baby and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Acute glomerulonephritis of baby is often referred to acute poststreptococcal glomerulonephritis, by after A group β hemolytic streptococcal infection, exudative, proliferative inflammation pathological changes in the diffusivity glomerular capillary that caused immune complex deposit causes at glomerule.Clinical manifestation weight differs, and typical case shows as edema, oliguria, hypertension.(acute glomerulonephritis is often referred to as acute nephritis.Broadly mean that one group of cause of disease and pathogeny differ, but clinical manifestation is Acute onset, with hematuria, edema, oliguria, hypertension and glomerular filtration rate, drops to a class renal glomerular disease of feature, therefore be also often called acute nephritic syndrome.Most acute poststreptococcal glomerulonephritises that belong on Pediatric Clinic.Primary disease can betide any age, is modal a kind of kidney disease in children's's period.With 3~8 years old in the majority, M-F is about 2: 1.Majority has Hemolytic streptococcus forerunner to infect history.) because Western medicine cannot effectively be treated acute glomerulonephritis of baby, and taking Western medicine has more side effect, and expense is high, so people exist great demand to the Chinese medicine of rapid, effective treatment acute glomerulonephritis of baby, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, has finally found the medicine of effective treatment acute glomerulonephritis of baby, thereby has completed the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment acute glomerulonephritis of baby.
Another object of the present invention has just been to provide the preparation method of this Chinese medicine composition.
Medicine of the present invention is to select Fructus Rosae Laevigatae, Herba Hedyotidis Diffusae, Herba Pogostemonis, Pericarpium Granati, Radix Mimosae Pudicae, Herba Leonuri, Pericarpium Arecae, Herba Cirsii, Flos Sophorae, Fructus Jujubae, Semen Armeniacae Amarum, Concha Ostreae, Herba Rostellulariae, Cortex Acanthopancis, Folium et Ramulus Clerodendri Trichotomi, Herba Artemisiae Anomalae, Herba Spirodelae, Spina Gleditsiae, Stigma Maydis, Herba Pyrolae, Herba Verbenae, Periostracum Cicadae, Cordyceps, Folium Isatidis, Herba Dianthi, Calyx Seu Fructus Physalis, Radix Pseudostellariae, Herba Menthae, Cortex Mori, Herba Eupatorii, Spora Lygodii medicine to combine preparation, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat acute glomerulonephritis of baby.Select Fructus Rosae Laevigatae to be because its nature and flavor are sour and astringent, flat, there is reinforcing the kidney and controlling nocturnal emission, the function of reducing urination and antidiarrheal, controls spermatorrhea, the enuresis, frequent micturition, insufficiency of the spleen dysentery.Select Herba Hedyotidis Diffusae to be because its property bitter but sweet flavor is cold, enter the heart, liver, spleen three warps, have heat clearing away, dampness removing, the function of removing toxic substances, controls dyspnea and cough due to lung-heat, tonsillitis, pharyngolaryngitis, appendicitis, dysentery, jaundice, pelvic inflammatory disease, adnexitis, carbuncle furuncle, venom.Select Herba Pogostemonis be because its nature and flavor pungent, tepor, enters lung, spleen, stomach warp, has fast gas, and in, ward off dirty, the function of damp eliminating, the heat-damp in summer that cures cold, cold and heat, headache, breast gastral cavity painful abdominal mass is vexed, vomiting is had loose bowels, malaria, dysentery, halitosis.Select Pericarpium Granati to be because its nature and flavor are sour and astringent, temperature, poisonous, enter large intestine, kidney channel, there is astringing intestine to stop diarrhea, hemostasis, the function of anthelmintic, controls chronic diarrhea, and chronic dysentery is had blood in stool, proctoptosis, spermatorrhea, metrorrhagia, leukorrhagia, abdominal pain due to worm stagnation, scabies.Selecting Radix Mimosae Pudicae is due to the puckery micro-hardship of its nature and flavor, and temperature is poisonous, has relieving cough and resolving phlegm, dampness removing dredging collateral, and stomach function regulating, the function of removing food stagnancy, controls chronic bronchitis, rheumatalgia, chronic gastritis, infantile dyspepsia.Select Herba Leonuri to be because its nature and flavor are arduous, cool, enter pericardium, Liver Channel, invigorate blood circulation, blood stasis dispelling, regulating menstruation, the function of the water that disappears, controls menoxenia, controls Lou difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Select Pericarpium Arecae to be because its nature and flavor are pungent, tepor, enters spleen, stomach, intestine and small intestine warp, has therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, and the function of row water is controlled gastral cavity abdomen painful abdominal mass swollen, beriberi, edema.Select Herba Cirsii to be because its nature and flavor are pungent, temperature, enters spleen, stomach two warps, has warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, and rapid digestion of food, the function of parasite killing, controls vomiting and diarrhoea, trusted subordinate's distending pain, furuncle toxic swelling skin ulcer, poisonous insect flood dragon wound.Select Flos Sophorae to be because its nature and flavor are bitter, cool, enter liver, large intestine channel, have heat clearing away, removing heat from blood, the function of hemostasis, controls discharging fresh blood stool, hemorrhoidal bleeding, hematuria, stranguria with blood, metrorrhagia, epistaxis, under dysentery with red and white feces, wind heat conjunctival congestion, skin sore, and for prevention of stroke.Select Fructus Jujubae to be because its nature and flavor are sweet, temperature, enters spleen, stomach warp, has spleen reinforcing stomach function regulating, and supplementing QI for promoting the production of body fluid adjusts battalion to defend, and separates the function of poison of drug, controls insufficiency of stomach lack of appetite, the weak loose stool of spleen, and qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Select Semen Armeniacae Amarum to be because its nature and flavor are bitter, temperature, poisonous, enter lung, large intestine channel, there is expelling phlegm for arresting cough, to relieving asthma, the function of intestine moistening, controls exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.Select Concha Ostreae to be because its nature and flavor are salty and bitter, cool, enter liver, kidney channel, have yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduces phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select Herba Rostellulariae to be because its nature and flavor are salty pungent, cold, enter liver, gallbladder two warps, there is heat-clearing and toxic substances removing, dampness removing disappears stagnant, the function of promoting blood circulation and stopping pain, the heating that cures cold, cough, laryngalgia, malaria, jaundice, nephritis edema, bones and muscles pain, infantile malnutrition, carbuncle furuncle, traumatic injury.Select Cortex Acanthopancis to be because its nature and flavor are pungent, temperature, enters liver, kidney channel, has wind-damp dispelling, strengthening bone and muscle, and the function of blood circulation and promoting silt, controls anemofrigid-damp arthralgia, and muscles and bones contraction is anxious, lumbago, sexual impotence, flaccidity of the lower limbs, children's's walking retardation in children, edema, beriberi, skin ulcer cellulitis toxic swelling, traumatic injury impairment caused by overstrain.Select Folium et Ramulus Clerodendri Trichotomi to be because its nature and flavor hardship is with sweetly, have wind-damp dispelling, the function of blood pressure lowering, dispelling the wind and dampness pathogens arthralgia pain, hemiplegia, hypertension, migraine, malaria, dysentery, hemorrhoid, carbuncle skin ulcer scabies.Select Herba Artemisiae Anomalae to be because its nature and flavor are bitter, temperature, enters the heart, spleen channel, has removing blood stasis to stimulate the menstrual flow, and the function of healing up sore and subduing swelling, controls amenorrhea and mass in the abdomen, chest and abdomen swelling and pain, puerperal blood stasis, traumatic injury, incised wound is hemorrhage, Yong Du burning swelling.Select Herba Spirodelae to be because its nature and flavor are pungent, cold, enter lung meridian, there is diaphoresis, dispel the wind, row water, heat clearing away, the function of removing toxic substances, row calentura while controlling, macule is not saturating, wind heat urticaria, skin pruritus, edema, the difficulty in urination, skin ulcer tinea, erysipelas, scalds.Select Spina Gleditsiae to be because its nature and flavor are pungent, temperature, searches wind, draw out pus by applying a plaster to the affected part, and detumescence, the function of evacuation of pus, controls carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.Select Stigma Maydis to be because its nature and flavor are sweet, flat, there is diuresis, expel the heat-evil, suppressing the hyperactive liver, the function of function of gallbladder promoting, controls oedema due to nephritis, beriberi, icterohepatitis, hypertension, cholecystitis, cholelithiasis, diabetes, hematemesis and epistaxis, nasal sinusitis, acute mastitis.Selecting Herba Pyrolae is that temperature, enters liver, kidney two warps, has tonify deficiency because of its nature and flavor sweetness and bitterness, kidney tonifying, and expelling wind and removing dampness, the function of promoting blood flow to regulate menstruation, controls weak cough, over-strained hemoptysis, rheumatic arthritis, metrorrhagia, leucorrhea, traumatic hemorrhage.Select Herba Verbenae to be because its nature and flavor are bitter, cool, enter liver, spleen channel, have heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, the function of inducing diuresis to remove edema, controls fever caused by exogenous pathogens, jaundice due to damp-heat, edema, dysentery, malaria, diphtheria, sore throat, gonorrhea, amenorrhea , mass in the abdomen, carbuncle sore tumefacting virus ulcerative gingivitis.Selecting Periostracum Cicadae is because its property sweet-salty, cool, enters lung, Liver Channel, has loose wind heat, and lung qi dispersing determine the function of convulsion, controls affection due to external wind and heat, cough hoarseness, and measles is thoroughly not smooth, rubella pruritus, little youngster shies Epilepsy, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.Select Cordyceps to be because its nature and flavor are sweet, temperature, enters lung, kidney two warps, has tonifying deficiency, and the function of beneficial vital essence is controlled phlegm retention and breathed heavily and cough, dyspnea due to deficiency, and consumptive disease is coughed, spitting of blood, spontaneous sweating, impotence and seminal emission, soreness of waist and knee joint, prolonged deficiency is multiple after being ill.Select Folium Isatidis to be because its nature and flavor are bitter, cold, enter liver, the heart, stomach warp, there is heat clearing away, removing toxic substances, removing heat from blood, the function of hemostasis, controls epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spits blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Select Herba Dianthi to be because its nature and flavor are bitter, cold, enter the heart, kidney, small intestinal, urinary bladder channel, there is clearing away heat and promoting diuresis, the function that removing blood stasis stimulates the menstrual flow, controls urinary obstruction, gonorrhea, edema, amenorrhea, carbuncle, conjunctival congestion is hidden from view, contamination sore.Select Calyx Seu Fructus Physalis to be because its nature and flavor are bitter, cold, return Liver Channel, there is heat-clearing and toxic substances removing, sore-throat relieving, reduces phlegm, and the function of diuresis is controlled pharyngalgia hoarseness, phlegm-heat cough, dysuria, external treatment pemphigus, eczema.Selecting Radix Pseudostellariae is that tepor, enters the heart, spleen, lung three warps, has the function of tonifying the lung, spleen invigorating, controls cough due to deficiency of the lung because of its nature and flavor sweetness and bitterness, insufficiency of the spleen lack of appetite, and cardiopalmus order antiperspirant, spirit is tired.Select Herba Menthae to be because its nature and flavor are pungent, cool, enter lung, Liver Channel, have dispelling wind, heat radiation, wards off dirtyly, and the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Select Cortex Mori to be because its nature and flavor are sweet, cold, enter lung, spleen channel, there is eliminating pathogen from the lung for relieving asthma, the function of line water detumescence, controls dyspnea and cough due to lung-heat, spits blood, edema, beriberi, dysuria.Select Herba Eupatorii to be because its nature and flavor are pungent, flat, enter spleen, stomach warp, have clearing away summer-heat, ward off dirty, removing dampness, the function of regulating menstruation, controls and experiences heat-damp in summer, cold and heat headache, accumulates in damp, gastral cavity painful abdominal mass is not hungry, sweet taste in the mouth greasy fur, menoxenia.Select Spora Lygodii to be because its property slightly sweet flavor is cold, enter small intestinal, urinary bladder channel, have heat-clearing and toxic substances removing, the function of relieving stranguria by diuresis, controls urinary tract infection, lithangiuria, nebulousurine, leucorrhea, hepatitis, oedema due to nephritis, laryngopharynx swelling and pain, mumps, enteritis, dysentery, skin eczema, herpes zoster.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight
Fructus Rosae Laevigatae 10-20 gram of Herba Hedyotidis Diffusae 5-15 gram of Herba Pogostemonis 6-16 gram
Pericarpium Granati 8-16 gram of Radix Mimosae Pudicae 10-18 gram of Herba Leonuri 8-20 gram
Pericarpium Arecae 8-15 gram of Herba Cirsii 6-15 gram of Flos Sophorae 8-16 gram
Fructus Jujubae 6-15 gram of Semen Armeniacae Amarum 8-15 gram of Concha Ostreae 5-15 gram
Herba Rostellulariae 5-12 gram of Cortex Acanthopancis 5-10 gram of Folium et Ramulus Clerodendri Trichotomi 5-18 gram
Herba Artemisiae Anomalae 8-16 gram of Herba Spirodelae 10-20 gram of Spina Gleditsiae 6-15 gram
Stigma Maydis 8-18 gram of Herba Pyrolae 6-16 gram of Herba Verbenae 10-20 gram
Periostracum Cicadae 3-8 gram of Cordyceps 5-10 gram of Folium Isatidis 10-20 gram
Herba Dianthi 6-15 gram of Calyx Seu Fructus Physalis 5-12 gram of Radix Pseudostellariae 4-8 gram
Herba Menthae 6-15 gram of Cortex Mori 5-15 gram of Herba Eupatorii 5-12 gram
Spora Lygodii 6-15 gram
Be preferably
8 grams of 8 grams of Herba Pogostemoniss of 12 grams of Herba Hedyotidis Diffusaes of Fructus Rosae Laevigatae
10 grams of 12 grams of Herba Leonuris of 10 grams of Radix Mimosae Pudicaes of Pericarpium Granati
10 grams, 9 grams of Flos Sophoraes of 10 grams of Herba Cirsiis of Pericarpium Arecae
8 grams of 10 grams of Concha Ostreaes of 8 grams of Semen Armeniacae Amarums of Fructus Jujubae
6 grams of 6 grams of Folium et Ramulus Clerodendri Trichotomis of 8 grams of Cortex Acanthopanciss of Herba Rostellulariae
8 grams of 12 grams of Spina Gleditsiaes of 9 grams of Herba Spirodelaes of Herba Artemisiae Anomalae
10 grams of 8 grams of Herba Verbenae of 10 grams of Herba Pyrolaes of Stigma Maydis
12 grams of 8 grams of Folium Isatidiss of 5 grams of Cordyceps of Periostracum Cicadae
5 grams of 6 grams of Radix Pseudostellariaes of 8 grams of Calyx Seu Fructus Physaliss of Herba Dianthi
8 grams of 6 grams of Herba Eupatoriis of 8 grams of Cortex Mori of Herba Menthae
8 grams of Spora Lygodii
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Fructus Rosae Laevigatae: choose decontamination, cut two lobes, water slightly soaks, and pulls out, removes residual burr after moistening, digs clean hair, core, dry;
2, Herba Hedyotidis Diffusae: get crude drug, remove impurity, wash quickly is clean, slightly dries in the air, and cutting is dry, sieve dedust bits;
3, Herba Pogostemonis: choose decontamination, remove undesirable root and old stem, first leaf is taken separately and put, stem water runs through, and cutting is dried, then with leaf and even;
4, Pericarpium Granati: choose decontamination, remove residual interior flesh and son, clean, stripping and slicing, dries;
5, Radix Mimosae Pudicae: summer, autumn gather, and clean, and dry;
6, Herba Leonuri: choose decontamination, clean, run through, cutting, dries;
7, Pericarpium Arecae: choose clean impurity, rolloff makes soft, beats, and sieve removes spare;
8, Herba Cirsii: choose clean impurity, remove root, washing runs through, tangent plane dries;
9, Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
10, Fructus Jujubae: choose clean impurity, dry;
11, Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, soaks in cold water, sloughs kind of a skin, dries, winnows with a dustpan clean;
12, Concha Ostreae: clean, dry, pulverize use;
13, Herba Rostellulariae: gather after the beginning of autumn, dry;
14, Cortex Acanthopancis: choose clean impurity, wash, slightly section after profit, dry;
15, Folium et Ramulus Clerodendri Trichotomi: choose roguing grass, slightly soak with clear water, run through, be cut into the segment of l centimeter length, dry, raw using;
16, Herba Artemisiae Anomalae: choose clean impurity, remove root, water edulcoration, slightly soaks, and cutting is dried;
17, Herba Spirodelae: 6-9 fishes between the month, dries;
18, Spina Gleditsiae: choose decontamination, be soaked in water, run through rear section, dry;
19, Stigma Maydis: get crude drug, remove impurity, sieve dedust bits;
20, Herba Pyrolae: choose decontamination, sieve removes silt, cleans, and slightly profit, chops up, and dries;
21, Herba Verbenae: choose clean impurity, clean, soften cutting, dry;
22, Periostracum Cicadae: choose decontamination, clean and dry;
23, Cordyceps: remove impurity;
24, Folium Isatidis: choose decontamination and dead leaf, clean, slightly moisten, cutting, dries;
25, Herba Dianthi: choose clean impurity, remove undesirable root, clean, stewing profit, cutting, dries;
26, Calyx Seu Fructus Physalis: remove impurity, fruit stem;
27, Radix Pseudostellariae: extract fibrous root, dry;
28, Herba Menthae: choose clean impurity, remove undesirable root, first leaf is trembled and separately put down, then stem is sprayed to clear water, run through rear cutting, dry, then with leaf and even;
29, Cortex Mori: brush away ash bits, clean, run through rear shredding, dry;
30, Herba Eupatorii: choose clean impurity, wash, pull out, slightly, after profit, remove undesirable root, cutting, dries;
31, Spora Lygodii: cut off stem and leaf, be placed in the basket that is lined with paper or cloth, dry in lee: then rub, shake with hand rubbing, the spore of blade back is come off, then remove stem and leaf with dusting cover sieve.
Two, preparation
1, the Fructus Rosae Laevigatae of described weight, Herba Hedyotidis Diffusae, Herba Pogostemonis, Pericarpium Granati, Radix Mimosae Pudicae, Herba Leonuri, Pericarpium Arecae, Herba Cirsii, Flos Sophorae, Fructus Jujubae, Semen Armeniacae Amarum, Concha Ostreae, Herba Rostellulariae, Cortex Acanthopancis, Folium et Ramulus Clerodendri Trichotomi, Herba Artemisiae Anomalae, Herba Spirodelae, Spina Gleditsiae, Stigma Maydis, Herba Pyrolae, Herba Verbenae, Periostracum Cicadae, Cordyceps, Folium Isatidis, Herba Dianthi, Calyx Seu Fructus Physalis, Radix Pseudostellariae, Herba Menthae, Cortex Mori, Herba Eupatorii, Spora Lygodii are decocted with water twice, add for the first time 8 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time.
2, the medicinal residues after filtering are for the first time added to 6 times of amounts of water, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time.
3, merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 8 doses and takes.
Medicine of the present invention has heat-clearing and toxic substances removing, inducing diuresis and reducing edema function, is used for the treatment of acute glomerulonephritis of baby instant effect, good effect, does not recur.By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get 30 of West Germany rabbits, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 100 examples for medical treatment.
2, diagnostic criteria
After streptococcal infection, through 1~3 week asymptomatic intermission, there is edema, hypertension, hematuria.Acute stage, has antistreptolysin " 0 " to tire to increase more, SC lowering of concentration, and in urine, FDP increased content etc. more contributes to diagnosis.Indivedual patients have with acute congestive heart failure or hypertensive encephalopathy for symptom originally, or sickly just only have edema and hypertension and only have slightly or without routine urinalysis change etc.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, every day 2 times, each 1 dose 15 days is a course for the treatment of, takes continuously three courses for the treatment of.
4, efficacy assessment standard
Effective: the recovery from illness of acute glomerulonephritis of baby symptom, recovers normal;
Take a turn for the better: acute glomerulonephritis of baby symptom alleviates, and the state of an illness progressively takes a turn for the better;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy acute glomerulonephritis of baby patient of the present invention 100 examples, effective 91 examples of result, obvious effective rate is 91%, 2 examples that take a turn for the better, and improvement rate is 2%, invalid 7 examples, total effective rate is 93%.

Claims (3)

1. a medicine for the treatment of acute glomerulonephritis of baby, is characterized in that: it is to be made by the crude drug in following weight range:
Fructus Rosae Laevigatae 10-20 gram of Herba Hedyotidis Diffusae 5-15 gram of Herba Pogostemonis 6-16 gram
Pericarpium Granati 8-16 gram of Radix Mimosae Pudicae 10-18 gram of Herba Leonuri 8-20 gram
Pericarpium Arecae 8-15 gram of Herba Cirsii 6-15 gram of Flos Sophorae 8-16 gram
Fructus Jujubae 6-15 gram of Semen Armeniacae Amarum 8-15 gram of Concha Ostreae 5-15 gram
Herba Rostellulariae 5-12 gram of Cortex Acanthopancis 5-10 gram of Folium et Ramulus Clerodendri Trichotomi 5-18 gram
Herba Artemisiae Anomalae 8-16 gram of Herba Spirodelae 10-20 gram of Spina Gleditsiae 6-15 gram
Stigma Maydis 8-18 gram of Herba Pyrolae 6-16 gram of Herba Verbenae 10-20 gram
Periostracum Cicadae 3-8 gram of Cordyceps 5-10 gram of Folium Isatidis 10-20 gram
Herba Dianthi 6-15 gram of Calyx Seu Fructus Physalis 5-12 gram of Radix Pseudostellariae 4-8 gram
Herba Menthae 6-15 gram of Cortex Mori 5-15 gram of Herba Eupatorii 5-12 gram
Spora Lygodii 6-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
8 grams of 8 grams of Herba Pogostemoniss of 12 grams of Herba Hedyotidis Diffusaes of Fructus Rosae Laevigatae
10 grams of 12 grams of Herba Leonuris of 10 grams of Radix Mimosae Pudicaes of Pericarpium Granati
10 grams, 9 grams of Flos Sophoraes of 10 grams of Herba Cirsiis of Pericarpium Arecae
8 grams of 10 grams of Concha Ostreaes of 8 grams of Semen Armeniacae Amarums of Fructus Jujubae
6 grams of 6 grams of Folium et Ramulus Clerodendri Trichotomis of 8 grams of Cortex Acanthopanciss of Herba Rostellulariae
8 grams of 12 grams of Spina Gleditsiaes of 9 grams of Herba Spirodelaes of Herba Artemisiae Anomalae
10 grams of 8 grams of Herba Verbenae of 10 grams of Herba Pyrolaes of Stigma Maydis
12 grams of 8 grams of Folium Isatidiss of 5 grams of Cordyceps of Periostracum Cicadae
5 grams of 6 grams of Radix Pseudostellariaes of 8 grams of Calyx Seu Fructus Physaliss of Herba Dianthi
8 grams of 6 grams of Herba Eupatoriis of 8 grams of Cortex Mori of Herba Menthae
8 grams of Spora Lygodii.
3. according to the preparation method of medicine described in claim 1 or 2, it is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Fructus Rosae Laevigatae: choose decontamination, cut two lobes, water slightly soaks, and pulls out, removes residual burr after moistening, digs clean hair, core, dry;
(2) Herba Hedyotidis Diffusae: get crude drug, remove impurity, wash quickly is clean, slightly dries in the air, and cutting is dry, sieve dedust bits;
(3) Herba Pogostemonis: choose decontamination, remove undesirable root and old stem, first leaf is taken separately and put, stem water runs through, and cutting is dried, then with leaf and even;
(4) Pericarpium Granati: choose decontamination, remove residual interior flesh and son, clean, stripping and slicing, dries;
(5) Radix Mimosae Pudicae: summer, autumn gather, and clean, and dry;
(6) Herba Leonuri: choose decontamination, clean, run through, cutting, dries;
(7) Pericarpium Arecae: choose clean impurity, rolloff makes soft, beats, and sieve removes spare;
(8) Herba Cirsii: choose clean impurity, remove root, washing runs through, tangent plane dries;
(9) Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
(10) Fructus Jujubae: choose clean impurity, dry;
(11) Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, soaks in cold water, sloughs kind of a skin, dries, winnows with a dustpan clean;
(12) Concha Ostreae: clean, dry, pulverize use;
(13) Herba Rostellulariae: gather after the beginning of autumn, dry;
(14) Cortex Acanthopancis: choose clean impurity, wash, slightly section after profit, dry;
(15) Folium et Ramulus Clerodendri Trichotomi: choose roguing grass, slightly soak with clear water, run through, be cut into the segment of l centimeter length, dry, raw using;
(16) Herba Artemisiae Anomalae: choose clean impurity, remove root, water edulcoration, slightly soaks, and cutting is dried;
(17) Herba Spirodelae: 6-9 fishes between the month, dries;
(18) Spina Gleditsiae: choose decontamination, be soaked in water, run through rear section, dry;
(19) Stigma Maydis: get crude drug, remove impurity, sieve dedust bits;
(20) Herba Pyrolae: choose decontamination, sieve removes silt, cleans, and slightly profit, chops up, and dries;
(21) Herba Verbenae: choose clean impurity, clean, soften cutting, dry;
(22) Periostracum Cicadae: choose decontamination, clean and dry;
(23) Cordyceps: remove impurity;
(24) Folium Isatidis: choose decontamination and dead leaf, clean, slightly moisten, cutting, dries;
(25) Herba Dianthi: choose clean impurity, remove undesirable root, clean, stewing profit, cutting, dries;
(26) Calyx Seu Fructus Physalis: remove impurity, fruit stem;
(27) Radix Pseudostellariae: extract fibrous root, dry;
(28) Herba Menthae: choose clean impurity, remove undesirable root, first leaf is trembled and separately put down, then stem is sprayed to clear water, run through rear cutting, dry, then with leaf and even;
(29) Cortex Mori: brush away ash bits, clean, run through rear shredding, dry;
(30) Herba Eupatorii: choose clean impurity, wash, pull out, slightly, after profit, remove undesirable root, cutting, dries;
(31) Spora Lygodii: cut off stem and leaf, be placed in the basket that is lined with paper or cloth, dry in lee: then rub, shake with hand rubbing, the spore of blade back is come off, then remove stem and leaf with dusting cover sieve;
(2) preparation
(1) Fructus Rosae Laevigatae of described weight, Herba Hedyotidis Diffusae, Herba Pogostemonis, Pericarpium Granati, Radix Mimosae Pudicae, Herba Leonuri, Pericarpium Arecae, Herba Cirsii, Flos Sophorae, Fructus Jujubae, Semen Armeniacae Amarum, Concha Ostreae, Herba Rostellulariae, Cortex Acanthopancis, Folium et Ramulus Clerodendri Trichotomi, Herba Artemisiae Anomalae, Herba Spirodelae, Spina Gleditsiae, Stigma Maydis, Herba Pyrolae, Herba Verbenae, Periostracum Cicadae, Cordyceps, Folium Isatidis, Herba Dianthi, Calyx Seu Fructus Physalis, Radix Pseudostellariae, Herba Menthae, Cortex Mori, Herba Eupatorii, Spora Lygodii are decocted with water twice, add for the first time 8 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time;
(2) medicinal residues after filtering are for the first time added to 6 times of amounts of water, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time;
(3) merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 8 doses and takes.
CN201310677457.1A 2013-12-13 2013-12-13 Medicine for treating acute glomerulonephritis and preparation method thereof Expired - Fee Related CN103656294B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105616617A (en) * 2016-02-29 2016-06-01 张向华 Medicine for treating acute glomerulonephritis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101612329A (en) * 2008-06-27 2009-12-30 胡春艳 The brightic Chinese medicine of a kind of treatment
CN102416094A (en) * 2011-11-21 2012-04-18 王红 Traditional Chinese medicine for treating chronic nephritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101612329A (en) * 2008-06-27 2009-12-30 胡春艳 The brightic Chinese medicine of a kind of treatment
CN102416094A (en) * 2011-11-21 2012-04-18 王红 Traditional Chinese medicine for treating chronic nephritis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105616617A (en) * 2016-02-29 2016-06-01 张向华 Medicine for treating acute glomerulonephritis

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