CN103651434A - Complex insecticide - Google Patents

Abstract

The invention relates to a complex insecticide, which includes two active ingredients, i.e., abamectin and tetrachlorantraniliprole. The complex insecticide has the advantages of low toxicity, high efficiency, wider insecticidal spectrum and high insecticidal activity, can delay the drug resistance and prolong the efficacy duration with lower consumption, and is non-hazardous to crops.

Description

A kind of compounded pesticides

Technical field

The invention belongs to pesticide field, relate in particular to the compounded pesticides of a kind of Avermectin and tetrachloro insect amide.

Background technology

Avermectin (Abamectin) is that a class of first being developed by the large village of university, Japanese North Zhi Denghe U.S. Merck company has desinsection, kills mite, ten hexa-atomic Macrocyclic lactone compounds of eelworm-killing activity, and in streptomycete, streptomyces griseus Streptomyces avermitilis fermentation produces.Avermectin has stomach toxicity and action of contace poison to mite class and insect, can not ovicidal.What mechanism of action was different from general insecticide is to disturb neurophysiology movable, stimulate and discharge γ-aminobutyric acid, and aminobutyric acid has inhibitory action to arthropodan nerve conduction.There is paralysis symptom after contacting with Avermectin with insect larvae in mite class adult, nymph, inertia, does not take food, dead after 2～4 days.Because not causing that insect dewaters rapidly, so Avermectin lethal effect is slower.Though Avermectin has direct action of contace poison to insect predator and insect parasite, because plant surface is residual few, therefore very little to the damage of beneficial insect, antagonism insect has good preventive effect as diamond-back moth, leaf miner, two spotted spider mite etc.Avermectin can not moved by adsorption by soil in soil, and decomposed by microorganism, thereby in environment without cumulative function, can be used as a part of integrated control.

Tetrachloro insect amide is the first bisamide insecticides with independent intellectual property right of China by the research and development of China National Chemicals Import(Sinochem) subordinate Shenyang Chemical Engineering Inst, the mechanism of action is in conjunction with the ryanodine receptor in insect bodies, suppress insect's food-taking, cause that polypide shrinks, finally cause insect dead, various lepidopterous insects are shown to excellent control efficiency.The control target of tetrachloro insect amide relates to the insects such as Noctuidae, the colorado potato beetles of rolling up Noctuidae, Pyralidae, diamond-back moth section, coleoptera and weevil and dipterous Liriomyza, the control of insect is had the lasting period long (more than 14d), without cross tolerance and on useful insect, affects the features such as very little, the mechanism of action is novel, there is vast potential for future development.

Because agricultural pests is produced and caused very large loss to crops every year, agricultural chemicals is as the Main Means of chemical control agricultural pests, and application is very extensive at present.Along with the long-term a large amount of single use of agricultural chemicals, can cause insect to produce resistance, environment is caused to larger pollution.Field trial shows, the another kind of mixed pesticide that existing medicament is different from mechanism of action can not only be postponed resistance and be produced, can also improve drug effect and residual period, reduce usage amount, reduce peasant's dispenser cost, so we are composite in order to expand insecticidal spectrum by Avermectin and tetrachloro insect amide.Two kinds of active ingredients are composite, not only can effectively prevent and treat most of insect, reduce environmental pollution, can also improve drug effect and lasting period, reduced peasant's labour cost, there is good economic benefit.

Summary of the invention

The object of this invention is to provide that a kind of insecticidal activity is efficient, lasting effect is long, the compounded pesticides of the high and low poison of quick-acting, environmental protection.Be specifically related to the composition pesticide that Avermectin and tetrachloro insect amide are active ingredient.

In above-mentioned compounded pesticides, the weight ratio of Avermectin and tetrachloro insect amide is 1:500～10:1.

Utilize above-mentioned compounded pesticides, be equipped with the known auxiliary agent of those skilled in that art, with the known method of those skilled in that art, can make formulation of the present invention.Its formulation that can process is aqueous emulsion, suspending agent, water dispersible granules.

The advantage that the present invention has and beneficial effect: 1, desinsection scope is wide; 2, the lasting period is long; 3, low toxicity, noresidue, nuisanceless, environmentally safe; 4, use compound formulation, the reduction during all than single uses of the consumption of two kinds of insecticides, thus improved insecticidal effect, increased safety, reduced environmental pollution.

Imported cabbageworm (PierisrapaeLinne) claim again cabbage caterpillar, belong to Lepidoptera, Sulfur butterfly, all there is throughout the country generation, host plant has 35 kinds of 9 sections such as Cruciferae, composite family, Convolvulaceae, Liliaceae, Solanaceae, Chenopodiaceae, Amaranthaceae, the brassicaceous vegetable of mainly causing harm, is injured more serious with cabbage mustard, wild cabbage, cauliflower etc. especially.Cabbage caterpillar stings food host blade, only gnaws mesophyll before 2 ages, leaves layer of transparent epidermis, nibbles blade hole or incise after 3 ages, and when serious, blade is all eaten up, and only residual thick vein and petiole, cause total crop failure, easily causes the popular of soft rot of cabbage.When cabbage caterpillar takes food, while taking food, defecate is polluted.Larvae underwent 5 instars, manyly before 3 ages causes harm at blade back, goes to blade face and nibble after 3 ages, and the food ingestion of 4-5 instar larvaes accounts for 97% of whole larval phase food ingestion.

First applicant has carried out to Avermectin and tetrachloro insect amide the research that formula screens, the insecticidal activity of Avermectin, two kinds of active ingredients of tetrachloro insect amide is very high, effect feature for two kinds of compositions, is decided to be imported cabbageworm by the object of indoor biometrics, and concrete test situation and result are as follows:

Test medication adopts 92% Avermectin element and the former medicine of 96% tetrachloro insect amide, uses acetone that former medicine is dissolved, and by patent application people, is mixed with needed preparation.Matched proportion density according to setting, is mixed with desired concn liquid standby, and the former medicine using and auxiliary agent are other producers and buy.

The method of indoor biometrics is: adopt the mixed medicine method method of artificial feeding, the liquid being equipped with by setting concentration is evenly sneaked in the artificial feed of making, pour respectively while hot 12 orifice plates into cooling, 1 examination worm of every hole access, each is processed in triplicate, repeats 20 at every turn.Examination worm after processing in temperature for (25 ± 1) ℃, relative moisture be that 60%-80%, periodicity of illumination are to raise under L:D=(16:8) h condition, after processing, 48h checks examination worm death condition, records respectively total borer population and dead borer population.Data are processed by SPSS software statistics.Obtain toxicity regression formula, the lethal concentration of 50, correlation coefficient etc., and obtain co-toxicity coefficient by the abundant method of Sun Yun.

The co-toxicity of mixture preparation adopts the abundant co-toxicity coefficient method representation of Sun Yun:

The theoretical toxicity index TTI=∑ of mixture preparation (the toxicity index ATI of certain medicine * percentage of this pharmaceutically active ingredient in mixture).

It is synergistic effect that CTC is greater than at 120 o'clock, and being less than at 80 o'clock is antagonism, and 80～120 o'clock is addition.

The toxicity test result of the different proportionings of table 1 to imported cabbageworm

Analyze above-mentioned data determination result and show, when Avermectin and tetrachloro insect amide different proportion are composite, the co-toxicity coefficient of all compounded formulas is all greater than 120 respectively, all has obvious synergistic effect.After explanation is composite by two kinds of active ingredients, can there is good synergistic effect.Wherein the co-toxicity coefficient of proportioning five has reached 169.81 especially, for the highest in all proportionings.

Following instantiation is in order to further describe the present invention, but the present invention absolutely not only only limits to following these embodiment.In formula, percentage is all weight percentage, and the former medicine using and auxiliary agent are all bought from other producers.

Formulation examples is as follows:

One: 6% Avermectin tetrachloro insect amide suspending agent of example

Two: 46.5% Avermectin tetrachloro insect amide aqueous emulsions of example

Three: 40.16% Avermectin tetrachloro insect amide water dispersible granules of example

Four: 15.15% Avermectin tetrachloro insect amide aqueous emulsions of example

Five: 50.1% Avermectin tetrachloro insect amide suspending agents of example

Six: 20.4% Avermectin tetrachloro insect amide water dispersible granules of example

Seven: 30.2% Avermectin tetrachloro insect amide water dispersible granules of example

Eight: 11% Avermectin tetrachloro insect amide suspending agents of example

Nine: 5.5% Avermectin tetrachloro insect amide water dispersible granules of example

Ten: 2% Avermectin tetrachloro insect amide water dispersible granules of example

According to above-mentioned ten examples, carry out the experiment of the field control Brussels sprouts white butterfly of 6% Avermectin tetrachloro insect amide suspending agent and other compounded formulas, simultaneously by the Contrast on effect with 1% Avermectin SC, 20% tetrachloro insect amide SC, verify the synergistic effect after composite.Test site is Jianli city, Jingzhou Prefecture, Hubei Province, and the time is on July 20th, 2011, test tetra-processing of s altogether, and each processes four repetitions, community randomized arrangement, community area 95m ², the planting habit of all communities is all identical with local planting habit, records the dispenser same day and the synoptic data of a week thereafter, specific as follows:

Table 2 duration of test meteorological data

Investigation standard is: before dispenser, carry out radix investigation, after medicine, 1d, 3d, 7d, 15d carry out medicine " Invest, Then Investigate ", investigation method Wei Ge community is got wild cabbage 20 strains at random, the life or death number of statistics cabbage caterpillar, calculate lethality and decline rate, concrete data (data are the mean value of four repetitions) are as follows:

Table 36% Avermectin tetrachloro insect amide SC and the field control effectiveness test of other compounded formulas to imported cabbageworm

As can be seen from the above data, different formulations carries out in composite process, using under identical effective dose, after Avermectin and tetrachloro insect amide are composite, the preventive effect of preparation will be apparently higher than two kinds of single doses, 5.5% Avermectin tetrachloro insect amide WDG(example nine wherein) after medicine, the control rate of 14d reaches 93.99%, and for the highest in all examples, visible two kinds of compositions are composite good synergistic effect.Meanwhile, complex preparation 14d preventive effect after medicine is greater than 7d after medicine, compares with single dose, has extended the lasting period.Both are novel environment friendly formulation at composite formulation, and environmentally safe close friend reduces peasant's amount of labour, has good economic benefit.

Claims (3)

1. a compounded pesticides, is characterized in that, described compounded pesticides contains Avermectin and two kinds of active components of tetrachloro insect amide, and the weight ratio of described Avermectin and tetrachloro insect amide is 1:500～10:1.

2. compounded pesticides according to claim 1, is characterized in that, described compounded pesticides is made suspending agent, aqueous emulsion, water dispersible granules.

3. according to claim 1 or compounded pesticides claimed in claim 2, it is characterized in that: for preventing and treating imported cabbageworm.