CN103648528A - 番木瓜花叶病毒组合物及其用于刺激先天免疫应答的用途 - Google Patents

番木瓜花叶病毒组合物及其用于刺激先天免疫应答的用途 Download PDF

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CN103648528A
CN103648528A CN201280023824.XA CN201280023824A CN103648528A CN 103648528 A CN103648528 A CN 103648528A CN 201280023824 A CN201280023824 A CN 201280023824A CN 103648528 A CN103648528 A CN 103648528A
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papmv
virus
compositions
purposes
vlp
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阿兰·拉马尔
德尼·勒克莱尔
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Inst Nat de la Rech Scient
Folia Biotech Inc
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Folia Biotech Inc
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    • A61K39/12—Viral antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
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    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201280023824.XA 2011-05-13 2012-05-01 番木瓜花叶病毒组合物及其用于刺激先天免疫应答的用途 Pending CN103648528A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161485955P 2011-05-13 2011-05-13
US61/485,955 2011-05-13
PCT/CA2012/050278 WO2012155261A1 (en) 2011-05-13 2012-05-01 Papaya mosaic virus compositions and uses thereof for stimulation of the innate immune response

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CN103648528A true CN103648528A (zh) 2014-03-19

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CN201280023824.XA Pending CN103648528A (zh) 2011-05-13 2012-05-01 番木瓜花叶病毒组合物及其用于刺激先天免疫应答的用途
CN201280022947.1A Pending CN103687942A (zh) 2011-05-13 2012-05-01 病毒样颗粒及其制备方法

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CN201280022947.1A Pending CN103687942A (zh) 2011-05-13 2012-05-01 病毒样颗粒及其制备方法

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US (2) US20140154288A1 (https=)
EP (2) EP2707480B1 (https=)
JP (2) JP6093926B2 (https=)
CN (2) CN103648528A (https=)
AU (1) AU2012255595A1 (https=)
BR (2) BR112013029144A2 (https=)
CA (2) CA2835972A1 (https=)
DK (1) DK2707480T3 (https=)
MX (1) MX2013013228A (https=)
NO (1) NO2800866T3 (https=)
WO (2) WO2012155262A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140154288A1 (en) 2011-05-13 2014-06-05 Folia Biotech Inc. Papaya mosaic virus compositions and uses thereof for stimulation of the innate immune response
JP2016531927A (ja) * 2013-09-19 2016-10-13 フォリア バイオテック インコーポレイテッド 癌治療でのパパイヤモザイクウイルス及びウイルス様粒子
WO2015153883A1 (en) * 2014-04-02 2015-10-08 Case Western Reserve University Vaccination using plant virus particles linked to her2 antigens
US11998594B2 (en) 2014-04-02 2024-06-04 Case Western Reserve University Anti-cancer plant virus particles linked to HER2 antigens
CN107002085A (zh) * 2014-09-11 2017-08-01 卡迪拉保健有限公司 具有优异免疫学特性的优异的人乳头瘤病毒抗原和含有其的疫苗
WO2016127262A1 (en) * 2015-02-12 2016-08-18 Folia Biotech Inc. Multimerized orthomyxovirus nucleoprotein and uses thereof
GB201708709D0 (en) 2017-06-01 2017-07-19 Univ York Virus like particle
MX385484B (es) * 2017-06-28 2025-03-14 Univ Mexico Nac Autonoma Vlps derivadas de virus de planta con dsrna encapsidado y metodo de sintesis.
FR3106648B1 (fr) * 2020-01-28 2022-05-27 Arkema France Structure multicouche pour le transport ou le stockage de l’hydrogene

Citations (1)

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WO2008058396A1 (en) * 2006-11-15 2008-05-22 Folia Biotech Inc. Papaya mosaic virus-based vaccines for influenza

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US5443969A (en) 1992-10-29 1995-08-22 Rutgers University RNA packaging system
US8101189B2 (en) * 2002-07-05 2012-01-24 Folia Biotech Inc. Vaccines and immunopotentiating compositions and methods for making and using them
JP4953570B2 (ja) 2002-07-05 2012-06-13 フォリア バイオテック インコーポレイテッド アジュバントウィルス粒子
EP1644034B1 (en) * 2003-07-10 2011-01-12 Cytos Biotechnology AG Composition for enhancing an immune response comprising packaged virus-like particles
ATE472336T1 (de) 2003-10-22 2010-07-15 Id Biomedical Corp Quebec Zusammensetzungen und verfahren zur aktivierung der eigenen und allergischen immunität
CA2669345A1 (en) * 2006-11-15 2008-05-22 Folia Biotech Inc. Immunogenic affinity-conjugated antigen systems based on papaya mosaic virus and uses thereof
US7799281B2 (en) 2007-01-16 2010-09-21 Festo Corporation Flux concentrator for biomagnetic particle transfer device
WO2008089569A1 (en) * 2007-01-26 2008-07-31 Folia Biotech Inc. Papaya mosaic virus-based vaccines against salmonella typhi and other enterobacterial pathogens
CA2742288A1 (en) 2008-07-30 2010-02-04 Folia Biotech Inc. Multivalent vaccines based on papaya mosaic virus and uses thereof
WO2010030790A2 (en) 2008-09-10 2010-03-18 The Texas A&M University System Methods and compositions for stimulation of mammalian innate immune resistance to pathogens
US20140154288A1 (en) 2011-05-13 2014-06-05 Folia Biotech Inc. Papaya mosaic virus compositions and uses thereof for stimulation of the innate immune response

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2008058396A1 (en) * 2006-11-15 2008-05-22 Folia Biotech Inc. Papaya mosaic virus-based vaccines for influenza

Non-Patent Citations (3)

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Title
PATRICK LACASSE ET AL: "Novel Plant Virus-Based Vaccine Induced Protective Cytotoxic T-Lymphocyte-Mediated Antiviral Immunity through Dendritic Cell Maturation", 《JOURNAL OF VIROLOGY》 *
SANDRA.S.DIEBOLD ET AL: "Innate Antiviral Responses by means of TLR7-Mediated Recognition of single-Stranded RNA", 《SCIENCE 》 *
TREMBLAY ET AL: "Effect o muatations K97A and E128A on RNA Binding and self assembly of papaya mosaic potexvirus coat protein", 《FEBS》 *

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Publication number Publication date
EP2707480B1 (en) 2017-08-02
EP2707027A1 (en) 2014-03-19
US20140154288A1 (en) 2014-06-05
CN103687942A (zh) 2014-03-26
US20140255439A1 (en) 2014-09-11
WO2012155262A1 (en) 2012-11-22
CA2835972A1 (en) 2012-11-22
US9833504B2 (en) 2017-12-05
BR112013029143A2 (pt) 2017-07-11
AU2012255595A1 (en) 2013-12-12
CA2835967A1 (en) 2012-11-22
JP2014514350A (ja) 2014-06-19
EP2707480A1 (en) 2014-03-19
MX2013013228A (es) 2013-12-12
JP6093926B2 (ja) 2017-03-15
JP6213461B2 (ja) 2017-10-18
WO2012155261A1 (en) 2012-11-22
BR112013029144A2 (pt) 2017-07-11
EP2707480A4 (en) 2015-01-07
JP2014519817A (ja) 2014-08-21
EP2707027A4 (en) 2015-06-03
DK2707480T3 (da) 2017-11-13
NO2800866T3 (https=) 2018-04-14

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