CN103638176A - Medicine for treating eczema and preparation method of medicine - Google Patents
Medicine for treating eczema and preparation method of medicine Download PDFInfo
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- CN103638176A CN103638176A CN201310672889.3A CN201310672889A CN103638176A CN 103638176 A CN103638176 A CN 103638176A CN 201310672889 A CN201310672889 A CN 201310672889A CN 103638176 A CN103638176 A CN 103638176A
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Abstract
The invention discloses a medicine for treating eczema and a preparation method of the medicine. The medicine is mainly prepared from centipede, swan-mussel, folium artemisiae argyi, calamine, buffalo horn, rosin, pepper, roughhaired holly root, gallnut and other medicines in a certain weight ratio. The medicine has the functions of clearing heat and removing toxicity, dispelling wind and relieving pain, cooling blood and eliminating edema, is quick in response and good in curative effect when used for treating eczema, and prevents relapse.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of eczema and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Eczema is that a kind of scytitis of the acute pruritus that caused by multiple internal and external factor reacts, it is a kind of common anaphylaxis dermatosis, conventionally the erythra of a series of lasting and superventions of general reference, with rubescent, edema, pruritus and dry be feature, can be with forming a scab, peel off, bubble, cracking, hemorrhage or oozing of blood.Its feature is violent pruritus, and skin lesion pleomorphism is symmetrical, has the tendency of oozing out, the chronic course of disease, easily outbreak repeatedly.Because Western medicine cannot effectively be treated eczema, so there is great demand to the Chinese medicine of rapid, effective treatment eczema in people, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, has finally found the medicine of effective treatment eczema, thereby has completed the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment eczema.
Another object of the present invention has just been to provide the preparation method of this Chinese medicine composition.
Medicine of the present invention is to select Scolopendra, Carnis Anodonta seu crislaria, Folium Artemisiae Argyi, Calamina, Cornu Bubali, Colophonium, Pericarpium Zanthoxyli, Herba Andrographis, Galla Chinensis, Plumbum preparatium, Calomelas, Fructus Evodiae, Squama Manis, pulverized limestone, Mel medicine to combine preparation, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat the recurrence of eczema.Wherein select Scolopendra to be because its nature and flavor are pungent, temperature, poisonous, enter Liver Channel, dispel the wind, arresting convulsion, counteracting toxic substances, the function of eliminating stagnation, controls apoplexy ， Jing Epilepsy, tetanus, pertussis, scrofula, tuberculosis ， mass in the abdomen tumor piece, sore swollen toxin, tinea corporis, bald in vain, anal fistula, scalds.Select Carnis Anodonta seu crislaria to be because its sweet in the mouth, salty enters liver, kidney channel, have YIN nourishing nourishing the liver, the function of clearing away heat to improve acuity of vision, treating the liver deficiency of the kidney yin, soreness of the waist and knees, eyes is dim-sighted, and tinnitus is dizzy, the dry many gums of eye; Yin asthenia generating intrinsic heat, dysphoria with smothery sensation taking fluids profusely, rapid digestion of food and polyorexia, polyuria, menorrhagia, leucorrhea, anal fistula, conjunctival congestion etc.Selecting Folium Artemisiae Argyi is because of its nature and flavor toil, temperature.Enter spleen, liver, kidney channel.The blood of regulating the flow of vital energy, by cold-damp; Warming the meridian, hemostasis, antiabortive.Control trusted subordinate's cold type of pain, the convulsion of having loose bowels, chronic dysentery, tells nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.Select Calamina to be because its nature and flavor are sweet, temperature, poisonous, enter meridian of Foot-JUE YIN, main tonify deficiency, the gas that dries, reason waist foot, removes haemorrhoids, parasite killing.Select Cornu Bubali to be because its nature and flavor hardship is salty, tremble with fear, have the function of heat clearing away, removing heat from blood, removing toxic substances, control calentura headache, high fever coma, macule, tells nosebleed, infantile convulsion, sore throat pharyngeal swelling.Selecting Colophonium is that temperature, enters liver, spleen channel because of its property bitter but sweet flavor, dispel the wind, and dampness, evacuation of pus, draws out pus by applying a plaster to the affected part, granulation promoting, the function of pain relieving, controls carbuncle, furunculosis, hemorrhoid complicated by anal fistula, malignant boil, scabies, bald in vain, incised wound, sprains, rheumatic arthralgia, leprosy pruritus.Select Pericarpium Zanthoxyli to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, lung, kidney channel, there is warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separate fish raw meat poison, control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, and cough with dyspnea, anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies.Select Herba Andrographis to be because its nature and flavor are bitter, cold in nature, nontoxic, enter the heart, lung two warps, have heat-clearing and toxic substances removing, the function of removing heat from blood detumescence, controls acute bacillary dysentery, gastroenteritis, flu, epidemic encephalitis, tracheitis, pneumonia, pertussis, pulmonary tuberculosis, lung abscess, cholecystitis, hypertension, epistaxis, oropharynx swells and ache, furuncle carbuncle, burn due to hot liquid or fire, venom.Select Galla Chinensis to be because its nature and flavor acid is flat.Enter lung, stomach, large intestine channel.Astringe the lung, astringing intestine to stop diarrhea, hemostasis, removing toxic substances.Control chronic cough of deficiency lung, chronic dysentery, chronic diarrhea, proctoptosis, spontaneous perspiration, night sweat, seminal emission, has blood in stool, epistaxis, metrorrhagia, traumatic hemorrhage, toxic swelling, furuncle, trichiasis.Selecting Plumbum preparatium, is because its nature and flavor are pungent salty, cold, poisonous, enters the heart, kidney two warps, has removing toxic substances, granulation promoting, and the function of eliminating phlegm down to arrest convulsion, controls carbuncle, ulcer, incised wound is hemorrhage, aphtha, the soup fire ， Jing Epilepsy of burning, demented.Select Calomelas to be because its nature and flavor are pungent, cold, poisonous, return liver, kidney, large intestine channel, there is counteracting toxic substances, putrefaction removing, the function of parasite killing, festers for skin infection outward, syphilis, rosacea, neurodermatitis; The removing food stagnancy that eliminates the phlegm for oral administration, the relieving constipation of relieving oedema or abdominal distension through diuresis or purgation, stagnant for sputum, edema expands, difficulty in urination and defecation.Select Fructus Evodiae to be because its nature and flavor are arduous, temperature, poisonous, enter liver, stomach warp, there is warming middle-JIAO, pain relieving, regulates the flow of vital energy, the function of dampness, stopping vomiting is against acid regurgitation, headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.Select Squama Manis to be because its nature and flavor are salty, cool, enter liver, stomach warp, have the routed carbuncle of detumescence, search wind active, the function of the stimulating milk secretion of stimulating the menstrual flow, controls carbuncle skin ulcer swollen, anemofrigid-damp arthralgia, amenorrhea, galactostasis, external hemostasis.Select Calx to be because its nature and flavor are pungent, temperature, poisonous, enter liver, spleen channel, there is dampness, parasite killing, hemostasis, analgesic therapy, the function of meat is disliked in erosion, controls scabies, eczema, wound hemorrhage, the burning hot wound of soup, hemorrhoid, proctoptosis, wart.Select Mel to be because its nature and flavor are sweet, flat, enter lung, spleen, large intestine channel, there is invigorating middle warmer, moisturize, pain relieving, the function of removing toxic substances, controls xeropulmonary cough, dryness of the intestine constipation, gastralgia, nasal sinusitis, aphtha, the burning hot wound of soup, separates Aconitum Carmichaeli.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight
10-20 gram of Folium Artemisiae Argyi 10-20 gram of Scolopendra 1-4 bar Carnis Anodonta seu crislaria
Calamina 12-22 gram of Cornu Bubali 6-12 gram of Colophonium 8-18 gram
Pericarpium Zanthoxyli 8-20 gram of Herba Andrographis 8-15 gram of Galla Chinensis 9-16 gram
Plumbum preparatium 8-18 gram of Calomelas 4-10 Fructus Evodiae 10-20 gram
Squama Manis 8-18 gram of Calx 8-18 gram of Mel 30-80 gram
Be preferably
12 grams of 15 grams of Folium Artemisiae Argyis of 2 Carnis Anodonta seu crislaria of Scolopendra
12 grams of 10 grams of Colophonium of 15 grams of Cornu Bubalis of Calamina
10 grams of 10 grams of Galla Chinensiss of 10 grams of Herba Andrographis of Pericarpium Zanthoxyli
12 grams of 5 grams of Fructus Evodiaes of 10 grams of Plumbum preparatiums Calomelas
50 grams of 15 grams of Mel of 15 grams of Calx of Squama Manis
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Scolopendra: wipe away only, remove cephalopodium, cut off use;
2, Carnis Anodonta seu crislaria: get fresh and alive mussel, except decapsidate, get fresh and alive Carnis Anodonta seu crislaria;
3, Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;
4, Calamina: choose decontamination, smash;
5, Cornu Bubali: rive, with hot-water soak, pull out, pound sheet, dries;
6, Colophonium: put in copper pot, use low baking temperature heat fused, drag for decontamination, in impouring water, wait cool rear taking-up, dry;
7, Pericarpium Zanthoxyli: remove fruit stem and seed Semen zanthoxyli, put pot interior stir-fry to making sound, oil goes out, and takes out, cool;
8, Herba Andrographis: remove impurity, wash quickly is clean, slightly moistens, and cutting is dry;
9, Galla Chinensis: choose clean, knock, remove wherein impurity open;
10, Plumbum preparatium: pure lead is placed in iron pan and is heated, fry and move, utilize air to make it oxidation, be then placed on pulverize in stone mortar, with water rinse, by thickness powder separately, drift out fine powder, then through being oxidized 24 hours, being ground into fine powder and sieving and get final product;
11, Calomelas: get crude drug, remove impurity, be ground into fine powder;
12, Fructus Evodiae: get crude drug, remove fruit stem, branch and impurity, sieve removes chip;
13, Squama Manis: get the Squama Manis sheet of choosing clean, separately size, separately puts sand in pot and make popular, adds Squama Manis sheet, fries to heaving while being golden yellow, takes out, and sieve shakeout, cools;
14, Calx: preparing quick lime, air slaking are powder;
15, Mel: get pure Mel, temper with slow fire, filter skimming.
Two, preparation
1, by the Scolopendra of described quantity and the Carnis Anodonta seu crislaria that takes out of shelling be placed in watt and dry.
2, the Folium Artemisiae Argyi of the Scolopendra of drying and Carnis Anodonta seu crislaria and described weight, Calamina, Cornu Bubali, Colophonium, Pericarpium Zanthoxyli, Herba Andrographis, Galla Chinensis, Plumbum preparatium, Calomelas, Fructus Evodiae, Squama Manis, Calx medicine are pulverized respectively, grind to the powder altogether.
3, by adding the Mel of described weight to mix well in ground described medicine smalls, make paste and get final product.
Medicine of the present invention has the function of heat-clearing and toxic substances removing, wind-expelling pain-stopping, removing heat from blood detumescence, is used for the treatment of eczema instant effect, good effect, does not recur.
By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get 30 of West Germany rabbits, male and female dual-purpose, body weight 2.0-2.5kg, first exposes skin by rabbit abdominal part hair removing, then by the Herbal medicines for external use mixing up at rabbit abdominal part baring skin place, then with gauze, twine and tie up, once, external application is 5 days continuously in drug of topical application every day, observes administration reaction every day, result shows that rabbit is movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 100 examples for medical treatment.
2, diagnostic criteria
Eczema can occur in any position of whole body, is often symmetric, and be generally and be confined to some position, and whole body universal eczema is very rare.Skin lesion shows as pleomorphism, i.e. erythema, pimple, papulovesicle, vesicle, erosion, ooze out, the various erythra such as incrustation, desquamation can cross-reference.That is to say, in same lesion, in contemporaneity, can occur above-mentioned 3～4 kinds of above infringements.Affected part inflammatory reaction is conventionally more obvious, and especially central part is more remarkable, often with rotten to the corn, ooze out.But disease damage indefinite border Chu, swelling is also lighter.
3, Therapeutic Method
Select above-mentioned medicament, to patient, be applied to affected part, drug of topical application every day 1 time, 15 days is a course for the treatment of, continuously two courses for the treatment of of the drug of topical application.
4, efficacy assessment standard
Effective: the recovery from illness of eczema symptom, recovers normal;
Take a turn for the better: eczema symptom alleviates, and the state of an illness progressively takes a turn for the better;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy eczema patients 100 examples of the present invention, effective 90 examples of result, obvious effective rate is 90%, 3 examples that take a turn for the better, and improvement rate is 3%, invalid 7 examples, total effective rate is 93%.
Claims (3)
1. a medicine for the treatment of eczema, is characterized in that: it is to be made by the crude drug in following weight range:
10-20 gram of Folium Artemisiae Argyi 10-20 gram of Scolopendra 1-4 bar Carnis Anodonta seu crislaria
Calamina 12-22 gram of Cornu Bubali 6-12 gram of Colophonium 8-18 gram
Pericarpium Zanthoxyli 8-20 gram of Herba Andrographis 8-15 gram of Galla Chinensis 9-16 gram
Plumbum preparatium 8-18 gram of Calomelas 4-10 Fructus Evodiae 10-20 gram
Squama Manis 8-18 gram of Calx 8-18 gram of Mel 30-80 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
12 grams of 15 grams of Folium Artemisiae Argyis of 2 Carnis Anodonta seu crislaria of Scolopendra
12 grams of 10 grams of Colophonium of 15 grams of Cornu Bubalis of Calamina
10 grams of 10 grams of Galla Chinensiss of 10 grams of Herba Andrographis of Pericarpium Zanthoxyli
12 grams of 5 grams of Fructus Evodiaes of 10 grams of Plumbum preparatiums Calomelas
50 grams of 15 grams of Mel of 15 grams of Calx of Squama Manis.
3. according to the preparation method of medicine described in claim 1 or 2, it is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Scolopendra: wipe away only, remove cephalopodium, cut off use;
(2) Carnis Anodonta seu crislaria: get fresh and alive mussel, except decapsidate, get fresh and alive Carnis Anodonta seu crislaria;
(3) Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;
(4) Calamina: choose decontamination, smash;
(5) Cornu Bubali: rive, with hot-water soak, pull out, pound sheet, dries;
(6) Colophonium: put in copper pot, use low baking temperature heat fused, drag for decontamination, in impouring water, wait cool rear taking-up, dry;
(7) Pericarpium Zanthoxyli: remove fruit stem and seed Semen zanthoxyli, put pot interior stir-fry to making sound, oil goes out, and takes out, cool;
(8) Herba Andrographis: remove impurity, wash quickly is clean, slightly moistens, and cutting is dry;
(9) Galla Chinensis: choose clean, knock, remove wherein impurity open;
(10) Plumbum preparatium: pure lead is placed in iron pan and is heated, fry and move, utilize air to make it oxidation, be then placed on pulverize in stone mortar, with water rinse, by thickness powder separately, drift out fine powder, then through being oxidized 24 hours, being ground into fine powder and sieving and get final product;
(11) Calomelas: get crude drug, remove impurity, be ground into fine powder;
(12) Fructus Evodiae: get crude drug, remove fruit stem, branch and impurity, sieve removes chip;
(13) Squama Manis: get the Squama Manis sheet of choosing clean, separately size, separately puts sand in pot and make popular, adds Squama Manis sheet, fries to heaving while being golden yellow, takes out, and sieve shakeout, cools;
(14) Calx: preparing quick lime, air slaking are powder;
(15) Mel: get pure Mel, temper with slow fire, filter skimming;
(2) preparation
(1) by the Scolopendra of described quantity and the Carnis Anodonta seu crislaria that takes out of shelling be placed in watt and dry;
(2) Folium Artemisiae Argyi of the Scolopendra of drying and Carnis Anodonta seu crislaria and described weight, Calamina, Cornu Bubali, Colophonium, Pericarpium Zanthoxyli, Herba Andrographis, Galla Chinensis, Plumbum preparatium, Calomelas, Fructus Evodiae, Squama Manis, Calx medicine are pulverized respectively, grind to the powder altogether;
(3) by adding the Mel of described weight to mix well in ground described medicine smalls, make paste and get final product.
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| CN201310672889.3A CN103638176B (en) | 2013-12-12 | 2013-12-12 | A kind of medicine for the treatment of eczema and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105853619A (en) * | 2016-05-06 | 2016-08-17 | 孙艳萍 | External-use ointment for treating eczema and preparation method |
| CN105998442A (en) * | 2016-07-24 | 2016-10-12 | 赵迎春 | External ointment for treating eczema and preparation method of external ointment |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312085A (en) * | 2000-03-08 | 2001-09-12 | 朱江 | Dermatosis treating medicine |
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2013
- 2013-12-12 CN CN201310672889.3A patent/CN103638176B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312085A (en) * | 2000-03-08 | 2001-09-12 | 朱江 | Dermatosis treating medicine |
Non-Patent Citations (2)
| Title |
|---|
| 程金丽,等: "湿疹的中医药治疗概况", 《药学实践杂志》 * |
| 陈平，等: "外用中药治疗慢性湿疹研究进展", 《中华中医药学刊》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105853619A (en) * | 2016-05-06 | 2016-08-17 | 孙艳萍 | External-use ointment for treating eczema and preparation method |
| CN105998442A (en) * | 2016-07-24 | 2016-10-12 | 赵迎春 | External ointment for treating eczema and preparation method of external ointment |
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| CN103638176B (en) | 2015-08-26 |
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Effective date of registration: 20201125 Address after: Room 1112, Zhongtai international building, zhangheng Road, zhangheng street, Nanyang City, Henan Province Patentee after: Henan moridi Biotechnology Co., Ltd Address before: 233500, Anhui City, Bozhou province Mengcheng County town of Changan community civilized Street 200 Patentee before: Su Zhenhua |