CN103638038A - Chinese caterpillar fungus recuperation oral liquid used for treating alopecia, and formulas thereof - Google Patents
Chinese caterpillar fungus recuperation oral liquid used for treating alopecia, and formulas thereof Download PDFInfo
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- CN103638038A CN103638038A CN201310579006.4A CN201310579006A CN103638038A CN 103638038 A CN103638038 A CN 103638038A CN 201310579006 A CN201310579006 A CN 201310579006A CN 103638038 A CN103638038 A CN 103638038A
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- oral liquid
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- cordycepin
- caterpillar fungus
- chinese caterpillar
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Abstract
The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a Chinese caterpillar fungus recuperation oral liquid used for treating alopecia, and formulas thereof. The Chinese caterpillar fungus recuperation oral liquid is made from cordycepin, salt, white granulated sugar, finasteride, and purified water. According to a first formula, the Chinese caterpillar fungus recuperation oral liquid is prepared by adding 5g of cordycepin, 20g of salt, and 50g of white granulated sugar into 1000ml purified water, and then is filled into 100 bottles with a volume of 10ml. According to a second formula, the Chinese caterpillar fungus recuperation oral liquid is prepared by adding 5g of cordycepin, 1g of finasteride, 20g of salt, and 50g of white granulated sugar into 1000ml purified water, and then is filled into 100 bottles with a volume of 10ml. Characteristics of the Chinese caterpillar fungus recuperation oral liquid are that: 1) the Chinese caterpillar fungus recuperation oral liquid is capable of preventing alopecia of human, and promoting hair regrowth preferably, and no side effect is caused; 2) the formulas are novel, technology is simple, preparation is convenient, and the Chinese caterpillar fungus recuperation oral liquid is suitable for large-scaled popularization in the industry.
Description
Technical field
The present invention relates to the technical field of Chinese medicine, specifically, is recuperate oral liquid and formula thereof of a kind of Cordyceps for the treatment of human body alopecia.
Background technology
Popular non-cordycepin hair dye and hair growth promoter has side effect, diseases such as allergy, lesions of liver and kidney more in the market.Also the report that has at present the non-cordycepin class of a lot of employings Chinese medicine hair growth, but formula is complicated mostly, and a lot of patients are difficult to adapt to the special taste of Chinese medicine, cause patient's compliance poor.
Some nearest researchs show, cordycepin has obvious curative effects taking good care of human body viscera function aspects, has the important function of regulate yin-yang, invigorating the liver and kidney, guarantor's taste, blood circulation promoting and blood stasis dispelling, and this is highly beneficial for the alopecia of prevention human body, hair restoration.
Summary of the invention
The object of this invention is to provide a kind of Cordyceps recuperate oral liquid and the formula thereof of alopecia, reach the object of the human hair of recuperating, prevention human hair comes off, and realizes hair restoration, avoids the drug side effect of patient's long-term taking simultaneously.
A kind of Cordyceps of the present invention recuperate alopecia oral liquid and formula be achieved by the following technical programs: it is made by cordycepin, Sal, white sugar, finasteride, pure water, described scheme one cordyceps militaris oral liquid formula is, get 5g cordycepin, 20g Sal and 50g white sugar, add 1000mL water to be mixed with oral administration solution, be distributed into the preparation of 100 bottles of 10mL, stored refrigerated, prepared preparation mouthfeel is good, there is no obvious medicine taste; Described scheme two cordyceps militaris oral liquid formulas are, get 5g cordycepin, 1g finasteride, 20g Sal and 50g white sugar, add 1000mL water to be mixed with oral administration solution, is distributed into the preparation of 100 bottles of 10mL, the mass ratio of cordycepin and finasteride is 4-6:1, stored refrigerated, prepared preparation mouthfeel is good, there is no obvious medicine taste.
A kind of Cordyceps of the present invention recuperate alopecia oral liquid with and formula compared with prior art have a following beneficial effect: because the present invention has adopted the active component of cordycepin as treatment human body alopecia medicine, realized the object of preventing human body alopecia, hair restoration, simultaneously, this oral liquid is free from side effects, be suitable for human body long-term taking, there is treatment and health care dual-use function.Feature of the present invention: 1) can realize preferably prevention human body alopecia and hair restoration function, have no side effect; 2) formula is novel, and technique is simple, is easy to preparation, is suitable in large-scale popularization in medicinal industry.
The specific embodiment
Below in conjunction with embodiment, the recuperate oral liquid of alopecia and a technical scheme left side for formula thereof of a kind of Cordyceps of the present invention is further described.
A kind of Cordyceps of the present invention recuperate oral liquid and the formula thereof of alopecia, it is made by cordycepin Sal, white sugar (3), finasteride, pure water raw material, it is characterized in that: described scheme one cordyceps militaris oral liquid formula is, get cordycepin 5g, Sal 20g and white sugar 50g, add pure water 1000mL to be mixed with oral administration solution, be distributed into the preparation of 100 bottles of 10mL, stored refrigerated, prepared preparation mouthfeel is good, there is no obvious medicine taste; Described scheme two cordyceps militaris oral liquid formulas are, get cordycepin 5g, finasteride 1g, Sal 20g and white sugar 50g, add pure water 1000mL to be mixed with oral administration solution, is distributed into the preparation of 100 bottles of 10mL, the mass ratio of cordycepin and finasteride is 4-6:1, stored refrigerated, prepared preparation mouthfeel is good, there is no obvious medicine taste.
Embodiment 1
Preparation scheme one cordyceps militaris oral liquid, gets 5g cordycepin, and 20g Sal and 50g white sugar add 1000mL water to be mixed with oral administration solution, are distributed into the preparation of 100 bottles of 10mL, stored refrigerated, and prepared preparation mouthfeel is good, there is no obvious medicine taste.
Embodiment 2
Preparation scheme two cordyceps militaris oral liquids, get 5g cordycepin, 1g finasteride, 20g Sal and 50g white sugar, add 1000mL water to be mixed with oral administration solution, is distributed into the preparation of 100 bottles of 10mL, stored refrigerated, prepared preparation mouthfeel is good, there is no obvious medicine taste.
3, pharmacodynamic experiment:
Major function and therapeutic domain: hair growth promoting, treatment hair comes off extremely, early whitening of beard and hair, male pattern alopecia.
Usage and consumption: embodiment 1 or embodiment 2 gained preparations are taken at bed time with one every day, and taking continuously 3 months is a course for the treatment of.
Clinical observation:
(1), physical data:
Observe case totally 230 examples, age 35-50 year, course of disease February～20 year.Be divided at random 3 groups, treatment A organizes 80 examples, gives the embodiment of the present invention 1 pharmaceutical preparation treatment; Treatment B group, gives the embodiment of the present invention 2 pharmaceutical preparation treatments; Matched group 70 examples, adopt conventional method treatment.
(2), diagnostic criteria:
Early stage the lighter's two temples place alopecias, forehead hairline place can be with alopecia, and along with aggravation, head hair reduces gradually; Alopecia process is that hair attenuates, deliquescing, shorten, and color and luster is thin out; When serious, merge in flakes in the alopecia district on temples and the crown, and hair exists only in occipitalia and both sides temples; Alopecia district skin smooth, oils and fats is more.
(3), Therapeutic Method:
Therapeutic Method is under the voluntary prerequisite of patient, patient is divided into 3 groups at random, treatment group 160 examples, and oral medicine of the present invention, patient is being taken at bed time with potion, and each 10mL, 3 months is a course for the treatment of; The oral finasteride of matched group, 1mg/ time, 1 times/day 3 months is a course for the treatment of.
(4), observation index:
Observation index is patient's regenerated hairs quantity, the mean of number count before and after hair therapy in the statistics patient crown and temples 1cm2 area.
(5), efficacy assessment standard:
Criterion of therapeutical effect is with reference to the criterion of therapeutical effect of alopecia in < < new Chinese medicine guideline of clinical investigations > >, and curative effect is divided into clinical recovery, effective, effective, invalid 4 grades.
Clinical recovery: hair stops coming off, and alopecia all grows, its distribution density, thickness, color and luster Yu Jianfa district are identical, and it is normal that sebum secretion recovers.
Effective: hair stops coming off, hair replacement reaches more than 70%, and its density, thickness and color and luster all approach Jian Fa district, and sebum secretion obviously reduces.
Effective: hair stops coming off, hair replacement reaches more than 30%, comprises that fine hair on birds or animals hair and poliosis grow.
Invalid: hair replacement less than 30% or still continue alopecia.
Total effective rate=(curing number of cases+effective number of cases+effective number of cases)/qualified case load * 100%.
(6), results and analysis (in Table 1):
Table 1 matched group and the comparison for the treatment of group curative effect
| Group | Case load | Recovery from illness | Effective | Effectively | Invalid | Total effective rate |
| Matched group | 70 | 2 | 10 | 35 | 23 | 67％ |
| Treatment A group | 80 | 15 | 26 | 30 | 9 | 89％ |
| Treatment B group | 80 | 20 | 34 | 19 | 7 | 91％ |
Treatment group curative effect is all obviously better than matched group as can be seen from Table 1, its total effective rate (89% and 91%) is apparently higher than matched group (67%), in addition, treatment B group recovery from illness quantity and effective quantity also, apparently higher than treatment A group, illustrate that cordycepin and finasteride have synergism on hair growth.
7. untoward reaction:
Treatment group is not found untoward reaction in treatment, blood, urine, just conventional, and hepatic and renal function and electrocardiogram are to be seen extremely.
The above is the preferred embodiments of the present invention; it should be pointed out that for those skilled in the art, do not departing under the prerequisite of principle of the present invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (1)
1. a kind of Cordyceps of the present invention oral liquid and formula thereof of alopecia of recuperating, it is made by cordycepin, Sal, white sugar, finasteride, pure water raw material, it is characterized in that: described scheme one cordyceps militaris oral liquid formula is, get cordycepin 5g, Sal 20g and white sugar 50g, add pure water 1000mL to be mixed with oral administration solution, be distributed into the preparation of 100 bottles of 10mL, stored refrigerated, prepared preparation mouthfeel is good, there is no obvious medicine taste; Described scheme two cordyceps militaris oral liquid formulas are, get cordycepin 5g, finasteride 1g, Sal 20g and white sugar 50g, add pure water 1000mL to be mixed with oral administration solution, is distributed into the preparation of 100 bottles of 10mL, the mass ratio of cordycepin and finasteride is 4-6:1, stored refrigerated, prepared preparation mouthfeel is good, there is no obvious medicine taste.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310579006.4A CN103638038A (en) | 2013-11-13 | 2013-11-13 | Chinese caterpillar fungus recuperation oral liquid used for treating alopecia, and formulas thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310579006.4A CN103638038A (en) | 2013-11-13 | 2013-11-13 | Chinese caterpillar fungus recuperation oral liquid used for treating alopecia, and formulas thereof |
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| CN103638038A true CN103638038A (en) | 2014-03-19 |
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| CN201310579006.4A Pending CN103638038A (en) | 2013-11-13 | 2013-11-13 | Chinese caterpillar fungus recuperation oral liquid used for treating alopecia, and formulas thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660118A (en) * | 2004-12-23 | 2005-08-31 | 鲁南制药股份有限公司 | Medication combination of containing finasteride and cyclodextrin or ramification |
| CN1745813A (en) * | 2005-09-05 | 2006-03-15 | 武汉麦迪生电子科技有限责任公司 | Activating element for preventing baldness |
| CN101984975A (en) * | 2010-10-29 | 2011-03-16 | 北京润德康医药技术有限公司 | Medical composition containing cordycepin derivatives |
-
2013
- 2013-11-13 CN CN201310579006.4A patent/CN103638038A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660118A (en) * | 2004-12-23 | 2005-08-31 | 鲁南制药股份有限公司 | Medication combination of containing finasteride and cyclodextrin or ramification |
| CN1745813A (en) * | 2005-09-05 | 2006-03-15 | 武汉麦迪生电子科技有限责任公司 | Activating element for preventing baldness |
| CN101984975A (en) * | 2010-10-29 | 2011-03-16 | 北京润德康医药技术有限公司 | Medical composition containing cordycepin derivatives |
Non-Patent Citations (2)
| Title |
|---|
| 刘阳 等: "养发虫草饮料的研制", 《食用菌》, 28 February 2009 (2009-02-28), pages 53 * |
| 王银银 等: "虫草素的功效研究进展", 《中国科技产业》, 31 May 2012 (2012-05-31) * |
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Application publication date: 20140319 |