CN115177683B - Traditional Chinese medicine composition for treating alopecia and application thereof - Google Patents
Traditional Chinese medicine composition for treating alopecia and application thereof Download PDFInfo
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- CN115177683B CN115177683B CN202211075364.7A CN202211075364A CN115177683B CN 115177683 B CN115177683 B CN 115177683B CN 202211075364 A CN202211075364 A CN 202211075364A CN 115177683 B CN115177683 B CN 115177683B
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Classifications
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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Abstract
The invention relates to a traditional Chinese medicine composition for treating alopecia and application thereof, in particular to a hair tonic and a preparation formula thereof, and belongs to the technical field of traditional Chinese medicines. A hair growth liquid is characterized in that the hair growth liquid comprises the following raw materials: 15-35 parts of dragon's blood, 15-50 parts of ginkgo leaf, 3-12 parts of cantharis, 15-30 parts of Chinese angelica, 20-35 parts of dangshen, 30-60 parts of hedysarum hedysari, 10-35 parts of lithospermum, 12-20 parts of angelica dahurica, 10-35 parts of drynaria rhizome, and the mass of each medicinal material in the formula is 1 g. The formula of the traditional Chinese medicine composition is completely summarized in clinical practice, the materials are common, the preparation process is simple, the traditional Chinese medicine composition can be prepared in daily families, the traditional Chinese medicine composition is innovated in research of traditional Chinese medicine and traditional Chinese medicine theory, the formula is unique, through clinical test, the traditional Chinese medicine composition passes through 3 treatment courses by external application, and a treatment course is within 15 days, so that the cure purpose can be achieved.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating alopecia and application thereof.
Background
Alopecia areata is a common skin condition in which the acquired hair suddenly comes out of the plaque and falls, which occurs mainly in the head and can also involve other hair growth sites of the body. The alopecia area is round, the size of the area is different, the skin of the affected part is smooth, the boundary is clear, no inflammation, scales and scars are generated, the alopecia area is usually found unintentionally, no subjective symptoms are generated, and mild tingling and itching feeling can be generated in the alopecia area. The disease appears in men and women, and can occur at any age, but patients are more common to young and middle-aged people. Investigation shows that the prevalence of alopecia areata in the population in China is about 0.27%, and foreign researches show that the prevalence of alopecia areata in the population in China is as high as 2% in lifetime.
Alopecia resulting from alopecia areata can cause some damage to the appearance of the patient, subjecting them to varying degrees of psychological stress and burden, and even affecting normal life, work and social contact, especially for patients suffering from alopecia totalis or alopecia universalis, which can directly lead to a reduction in their quality of life. Clinical studies show that the values of the depression self-measuring table and the anxiety self-measuring table of the alopecia areata patient are higher than those of normal people, and proper psychological intervention can reduce the level of the depression self-measuring table and the anxiety self-measuring table, promote the recovery of the disease, reduce the recurrence rate, and suggest that depression and anxiety can prevent improvement of alopecia areata, and the disease can increase negative emotion.
The name of the alopecia areata traditional Chinese medicine is "oil wind", and the ancient medical science is recorded on the disease for a long time, and has abundant diagnosis and treatment experience. Traditional Chinese medicine is applied to treat several pathogenesis of liver and kidney deficiency, qi and blood deficiency, blood heat and wind dryness, liver depression and blood stasis and the like, and both principal and secondary aspects of the disease are considered. The traditional medicine has a plurality of special therapies such as traditional Chinese medicine oral administration, external washing, acupuncture physiotherapy and the like, and has low toxic and side effects and flexible administration, and has attracted wide attention. The hair tonic prepared by the formula has good curative effects on treating alopecia areata and promoting the healing of crusting of burn wound surfaces, and has low cost, simple preparation process and easy industrial production.
Disclosure of Invention
The invention provides a traditional Chinese medicine composition for treating alopecia, which is prepared from the main raw materials of 15-35 parts of dragon's blood, 15-50 parts of ginkgo leaf, 3-12 parts of cantharis, 15-30 parts of Chinese angelica, 20-35 parts of radix codonopsis, 30-60 parts of hedysarum polybasic, 10-35 parts of lithospermum, 12-20 parts of radix angelicae, 10-35 parts of rhizoma drynariae, and the mass of each medicinal material is 1 g. The hair tonic liquid can be directly applied to stimulate hair follicle growth, and the absorbent cotton balls are dipped with a proper amount of the impregnant and lightly smeared on affected parts 3-5 times per day. The scalp is slightly and thinly broken like a foaming pattern after the scalp is generally used for 3-5 days, the scalp can be scab quickly after the application of the scalp is stopped, new hair can grow under the condition of scab removal of about 10 days, the maximum time is not longer than 15 days, and a treatment course is 15 days. After new hair grows, the hair can be continuously used for 1-2 treatment courses. In addition, the hair growth promoting liquid can be applied to burn and ulcer wound to promote wound crusting and healing.
The hair growth liquid prepared by the invention can effectively recover scalp hair follicles, normalize the functions of damaged hair follicles, improve the blood circulation of scalp, regulate and control the regeneration of hair follicles, remove toxic substances in hair follicles and achieve the effect of hair growth.
In order to achieve the above purpose, the present invention provides the following technical solutions:
s1, preparing cantharis from liquorice and glutinous rice: soaking 12 g of cantharis with the U-shaped feet removed in a soup prepared by adding 300ml of water into 36 g of liquorice and decocting with slow fire for about 30 minutes for 2 hours, picking up cantharis, sun-drying, adding 200 g of glutinous rice into a pot, and parching until the rice is golden yellow, and picking up cantharis;
s2, taking 15-35 parts of dragon' S blood, 15-50 parts of ginkgo leaf, 15-30 parts of Chinese angelica, 20-35 parts of radix codonopsis, 30-60 parts of hedysarum hedysari, 10-35 parts of lithospermum, 12-20 parts of radix angelicae and 10-35 parts of rhizoma drynariae, cleaning, placing into a glass bottle, adding 3-12 parts of cantharis, adding 1-g parts of medicinal materials into 800ml of 75% alcohol, adding 150ml of liquorice water which is used for soaking the cantharis, and sealing and soaking for 30 days to obtain a solution 1;
s3, adding 2500mg of cystine tablets into 50ml of sodium bicarbonate solution, soaking until the cystine tablets are completely dissolved to obtain solution 2;
s4, mixing solution 1+2=the hair growing liquid, and directly taking the hair growing liquid for external use, dipping a proper amount of the impregnant by using a absorbent cotton ball, lightly applying the impregnant to an affected part, wherein the scalp is slightly and thinly damaged like a foam after the application of the liquid for 3-5 days, scabbing can be quickly carried out after the application of the liquid, new hair can be grown under scabbing and scabbing removal for about 10 days, the maximum time is not more than 15 days, 15 days is a treatment course, and the liquid can be continuously used for 1-2 treatment courses after the new hair is grown.
Preferably, the cantharides used in the present invention are both clean cantharides with their cephalopods removed.
Preferably, the pretreatment of the cantharis in the invention is to soak 12 g of cantharis with the U-shaped feet removed in a soup of 36 g of liquorice and 300ml of slow fire for 30 minutes for 2 hours, then add 200 g of glutinous rice in a pot and fry until rice golden yellow to pick up cantharis.
Preferably, the raw materials in the invention mainly comprise the following components in parts by weight: 15-35 parts of dragon's blood, 15-50 parts of ginkgo leaf, 15-30 parts of Chinese angelica, 20-35 parts of radix codonopsis, 30-60 parts of hedysarum hedysari, 10-35 parts of lithospermum, 12-20 parts of radix angelicae, 10-35 parts of rhizoma drynariae, 3-12 parts of cantharis and 1-g parts of medicinal materials.
Preferably, the soaking time of solution 1 in the present invention is 30 days.
Preferably, the hair tonic prepared by the invention must be applied together with solution 1 and solution 2 to produce the effect.
Drawings
FIG. 1 is a graph showing the effect of the present invention before and after use of the formulation.
Detailed Description
The present invention will be described in further detail with reference to specific embodiments in order to make the objects, technical solutions and advantages of the present invention more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
S1, preparing cantharis from liquorice and glutinous rice: soaking 12 g of cantharis with the U-shaped feet removed in a soup prepared by adding 300ml of water into 36 g of liquorice and decocting with slow fire for about 30 minutes for 2 hours, picking up cantharis, sun-drying, adding 200 g of glutinous rice into a pot, and parching until the rice is golden yellow, and picking up cantharis;
s2, taking 15 parts of dragon' S blood, 15 parts of ginkgo leaf, 15 parts of Chinese angelica, 20 parts of radix codonopsis, 30 parts of hedysarum hedysari, 10 parts of lithospermum, 12 parts of radix angelicae and 10 parts of rhizoma drynariae, cleaning, placing into a glass bottle, adding 3 parts of cantharis, adding each part of medicinal materials with the mass of 1 g, adding 150ml of liquorice water which is used for soaking the cantharis in the original state into 800ml of 75% alcohol, and sealing and soaking for 30 days to obtain a solution 1;
s3, adding 2500mg of cystine tablets into 50ml of sodium bicarbonate solution, soaking until the cystine tablets are completely dissolved to obtain solution 2;
s4, mixing solution 1+2=the hair growing liquid, and directly taking the hair growing liquid for external use, dipping a proper amount of the impregnant by using a absorbent cotton ball, lightly applying the impregnant to an affected part, wherein the scalp is slightly and thinly damaged like a foam after the application of the liquid for 3-5 days, scabbing can be quickly carried out after the application of the liquid, new hair can be grown under scabbing and scabbing removal for about 10 days, the maximum time is not more than 15 days, 15 days is a treatment course, and the liquid can be continuously used for 1-2 treatment courses after the new hair is grown.
Comparative example 1 the procedure was the same as in example 1 except that in step S1, the pretreatment of cantharis was carried out without immersing in licorice water, and then parching with glutinous rice to golden yellow.
Glycyrrhrizae radix has effects of treating alopecia areata, wherein the occurrence of alopecia areata is related to immune dysfunction, and has effects of relieving inflammation and regulating immunity due to hair loss caused by local inflammatory reaction, so that it has certain effect on alopecia areata. The cantharides soaked by the liquorice is required to be fried to be golden yellow by adding the glutinous rice, because the cantharides are hot and spicy; it has the actions of breaking blood and eliminating mass, and eliminating toxic and sores, and its raw materials are used externally, and its cantharis stir-baked with glutinous rice can reduce toxicity and its smell can be corrected for oral administration to promote menstruation and break mass. The cantharides mainly contains cantharidin, fat, resin, formic acid, pigment and the like, and toxic components of the cantharidin are cantharidin, wherein the cantharidin starts to sublimate at 84 ℃, the sublimation point of the cantharidin is 110 ℃, the temperature of a rice frying pot is 128 ℃, the cantharidin is suitable for sublimating cantharidin, and the toxicity is reduced.
Example 2
S1, preparing cantharis from liquorice and glutinous rice: soaking 12 g of cantharis with the U-shaped feet removed in a soup prepared by adding 300ml of water into 36 g of liquorice and decocting with slow fire for about 30 minutes for 2 hours, picking up cantharis, sun-drying, adding 200 g of glutinous rice into a pot, and parching until the rice is golden yellow, and picking up cantharis;
s2, taking 20 parts of dragon' S blood, 25 parts of ginkgo leaf, 20 parts of Chinese angelica, 25 parts of codonopsis pilosula, 40 parts of hedysarum hedysari, 15 parts of lithospermum, 16 parts of angelica dahurica and 15 parts of rhizoma drynariae, cleaning, placing into a glass bottle, adding 6 parts of cantharis, adding each part of medicinal materials with the mass of 1 g, adding 150ml of liquorice water which is used for soaking the cantharis in the original state into 800ml of 75% alcohol, and sealing and soaking for 30 days to obtain a solution 1;
s3, adding 2500mg of cystine tablets into 50ml of sodium bicarbonate solution, soaking until the cystine tablets are completely dissolved to obtain solution 2;
s4, mixing the solution 1+2=the hair growth liquid, and directly applying the hair growth liquid for external use, wherein the hair growth can be stimulated, a proper amount of the impregnant is dipped by absorbent cotton balls, and the impregnant is lightly applied to an affected part for 3-5 times per day. The scalp is slightly and thinly broken like a foaming pattern after the scalp is generally used for 3-5 days, the scalp can be scab quickly after the application of the scalp is stopped, new hair can grow under the condition of scab removal of about 10 days, the maximum time is not longer than 15 days, and a treatment course is 15 days. After new hair grows, the hair can be continuously used for 1-2 treatment courses.
Comparative example 2 the procedure was the same as in example 2 except that dragon' S blood was not added in step S2.
According to the description of the outline of materia medica, the dragon's blood has warm and flat nature, sweet and salty taste, no toxicity, enters blood system, enters lung, spleen and kidney channels, and has the obvious effects of activating blood circulation to remove blood stasis, relieving swelling and pain, astringing and stopping bleeding, softening hardness to dissipate stagnation, promoting granulation and healing sore and the like. Modern medicine research proves that the dragon's blood capsule has the functions of improving body microcirculation, regulating body metabolism, improving body immunity and the like. In the invention, the dragon's blood can soften hardness and dissipate nodulation, activate blood and promote qi circulation. According to the traditional Chinese medicine, qi is the general of blood, blood is the mother of qi, qi flows and then blood flows, blood flows and stasis are removed, qi-flowing and blood flow stasis and vein circulation are carried out, and all the symptoms are naturally healed, so that the traditional Chinese medicine can activate blood and flow qi for the skin, and the vein of stasis and blockage is normal, thereby being beneficial to scalp metabolism, improving scalp environment, promoting new growth, healing burn wound surfaces and growing new skin.
Example 3
S1, preparing cantharis from liquorice and glutinous rice: soaking 12 g of cantharis with the U-shaped feet removed in a soup prepared by adding 300ml of water into 36 g of liquorice and decocting with slow fire for about 30 minutes for 2 hours, picking up cantharis, sun-drying, adding 200 g of glutinous rice into a pot, and parching until the rice is golden yellow, and picking up cantharis;
s2, taking 25 parts of dragon' S blood, 30 parts of ginkgo leaf, 25 parts of Chinese angelica, 30 parts of radix codonopsis pilosulae, 50 parts of hedysarum hedysari, 25 parts of lithospermum, 18 parts of radix angelicae, 25 parts of rhizoma drynariae, cleaning, placing into a glass bottle, adding 9 parts of cantharis, adding each part of medicinal materials with the mass of 1 g, adding 150ml of liquorice water which is used for soaking the cantharis in the original state into 800ml of 75% alcohol, and sealing and soaking for 30 days to obtain a solution 1;
s3, adding 2500mg of cystine tablets into 50ml of sodium bicarbonate solution, soaking until the cystine tablets are completely dissolved to obtain solution 2;
s4, mixing solution 1+2=the hair growing liquid, and directly and externally applying the hair growing liquid to stimulate hair follicle growth, dipping a proper amount of the impregnant by using a absorbent cotton ball, lightly applying the impregnant to an affected part, wherein the scalp is slightly and thinly damaged like a foam after the application of the liquid for 3 to 5 days, scab can be formed quickly after the application of the liquid, new hair can be grown under scab decrustation for about 10 days, the maximum time is not more than 15 days, and a treatment course is 15 days. After new hair grows, the hair can be continuously used for 1-2 treatment courses.
Comparative example 3 the procedure was the same as in example 3 except that ginkgo leaf was not added in the step S2.
Comparative example 4 the procedure was the same as in example 3 except that no angelica was added in step S2.
Comparative example 5 the procedure was the same as in example 3 except that dangshen was not added in step S2.
Comparative example 6 the procedure was the same as in example 3 except that hedysari was not added in step S2.
Comparative example 7 the procedure was the same as in example 3 except that no arnebia root was added in step S2.
Comparative example 8 the procedure was the same as in example 3 except that no dahurian angelica root was added in step S2.
Comparative example 9 the procedure was the same as in example 3 except that no drynaria was added in step S2.
The occurrence of alopecia areata is closely related to liver, spleen, kidney, heart and lung, and the treatment is mainly treating liver, spleen and kidney are auxiliary, and the treatment is repeated in succession. Liver governs storing blood, and body yin governs yang, and is good at regulating blood volume. Liver blood is abundant and blood is abundant, so that skin and hair orifices can be nourished, and hair can grow normally, and black and bright. Liver governs smoothing flow of qi, qi movement is smooth, spleen and stomach can normally transport and transform, qi, blood and body fluids can normally distribute and metabolize, and hair can be nourished. Spleen and stomach serve as the source of qi and blood and the ascending and descending pivot, so that spleen qi is sufficient to transport essence of water to skin and hair of the whole body, so that the skin and the hair are compact and dense. Kidney stores essence, and essence can produce blood, and liver and kidney are homologous, so liver blood is abundant with help of kidney essence, and kidney essence is abundant, hair is moist and bright and black.
The gingko She Guixin and the lung meridian have the effects of promoting blood circulation to remove blood stasis, dredging collaterals, relieving pain, astringing lung, relieving asthma, eliminating turbid pathogen and reducing blood fat, have good effects of improving blood flow, and can directly promote healthy regeneration of hair as the hair root is sufficiently nourished along with the increase of blood flow.
Dang Gui and Lithospermum are both indicated for blood deficiency with the effects of nourishing blood, activating blood and cooling blood. The Chinese angelica root enters liver, heart and spleen channels, has the effects of enriching blood and activating blood, and the lithospermum is salty and cold in liver channel blood, can cool blood and activate blood, can detoxify and promote eruption, is used for treating diseases such as warm toxin and spot, severe deficiency heat toxin, skin appearance of purple black spot and the like, has the effects of clearing heat and cooling blood, can be used for treating burns and scalds, can be used for filtering and oil-taking and smearing on affected parts after the lithospermum is soaked in sesame oil, and has obvious effect.
The radix codonopsis is a traditional Chinese medicine for tonifying qi, has flat property and sweet taste, has the effects of tonifying middle-jiao and Qi, can regulate inappetence, deficiency and lassitude caused by deficiency of middle-jiao, has the effects of invigorating spleen and lung channel, and can improve the functions of lung and spleen and stomach.
Hedysari is sweet in taste and warm in nature, enters lung and spleen meridians, has the effects of tonifying qi and consolidating exterior, can tonify spleen qi, is a source of qi and blood biochemistry, and can strengthen the blood replenishing and nourishing effects of Chinese angelica because of being often combined with Chinese angelica.
Bai Zhi enters lung, spleen and stomach meridians. Has effects in dispelling pathogenic wind, eliminating dampness, relieving swelling and pain;
rhizoma drynariae has the effects of invigorating the kidney and strengthening bones, and is recorded in Fujian Chinese herbal medicine: "treating alopecia areata": five fresh drynaria fortunei, five cantharides, three or two distilled liquor, soaking for twelve days, filtering and rubbing the affected parts for two to three times daily. "
Bai Zhi has the actions of invigorating spleen and drying dampness, can alleviate the greasy taste of Dang Shen, and can be used as an adjuvant drug for its actions of making rhizoma Drynariae and cantharis warm and dry. The whole prescription is used together for nourishing but not greasy, warming but not dry, has the effects of tonifying and discharging, nourishing liver and kidney, nourishing yin and clearing heat, and tonifying qi and enriching blood, and has obvious effects of clinically treating alopecia areata caused by liver and kidney deficiency, qi and blood deficiency and blood hot air dryness. Therefore, the drugs for supplementing qi are mostly used for supplementing qi, nourishing blood and promoting blood circulation, and the methods of soothing liver, regulating qi, promoting blood circulation, removing blood stasis and dredging meridian passage can lead to qi and blood double-supplementing, qi movement regulating, blood circulation and meridian passage, so that the blood is abundant, and the blood circulation is normal and the hair is nourished. The formula has remarkable effect on promoting skin tissue regeneration, so that the formula can be used for treating burn wound crusting and healing.
Example 4
S1, preparing cantharis from liquorice and glutinous rice: soaking 12 g of cantharis with the U-shaped feet removed in a soup prepared by adding 300ml of water into 36 g of liquorice and decocting with slow fire for about 30 minutes for 2 hours, picking up cantharis, sun-drying, adding 200 g of glutinous rice into a pot, and parching until the rice is golden yellow, and picking up cantharis;
s2, cleaning 35 parts of dragon' S blood, 50 parts of ginkgo leaf, 30 parts of Chinese angelica, 35 parts of codonopsis pilosula, 60 parts of hedysarum hedysari, 35 parts of lithospermum, 20 parts of angelica dahurica and 35 parts of drynaria rhizome, placing into a glass bottle, adding 12 parts of cantharis, adding 1-g parts of each medicinal material, adding 150ml of liquorice water which is used for soaking the cantharis in the original solution into 800ml of 75% alcohol, and sealing and soaking for 30 days to obtain a solution 1;
s3, adding 2500mg of cystine tablets into 50ml of sodium bicarbonate solution, soaking until the cystine tablets are completely dissolved to obtain solution 2;
s4, mixing solution 1+2=the hair growing liquid, and directly and externally applying the hair growing liquid to stimulate hair follicle growth, dipping a proper amount of the impregnant by using a absorbent cotton ball, lightly applying the impregnant to an affected part, wherein the scalp is slightly and thinly damaged like a foam after the application of the liquid for 3 to 5 days, scab can be formed quickly after the application of the liquid, new hair can be grown under scab decrustation for about 10 days, the maximum time is not more than 15 days, and a treatment course is 15 days. After new hair grows, the hair can be continuously used for 1-2 treatment courses.
To further verify the efficacy of the finished formulations of the present invention, we performed corresponding clinical trials on the finished drugs prepared in the above specific examples 1-4 and comparative examples 1-9, and the results of the specific clinical trials were reported as follows:
clinical observation and curative effect: 390 patients from the dermatological clinic were selected to meet the criteria for diagnosis of alopecia areata. Wherein 200 men and 190 women are aged 37-63 years, the course of disease is 30 d-1.5 years, the average course of disease (1.26+ -0.35) is 1-5 skin lesions, and the alopecia area is 0.5cm×1.0 cm-5.0 cm×7.0cm. Eliminating toxic alopecia of plum, androgenetic alopecia, etc. Has no hypertension, diabetic aldosteronism, hypokalemia, liver and kidney insufficiency, pregnant woman and lactation patient. Patients were divided into example 1, 2, 3, 4, comparative example 1, comparative example 2, comparative example 3, comparative example 4, comparative example 5, comparative example 6, comparative example 7, comparative example 8, comparative example 9; the differences of the groups have no statistical significance in general data such as gender, age, disease course, disease condition and the like, and have comparability (P is more than 0.05).
Treatment criteria and treatment effect: and (3) healing: the new hair grows completely, the color, thickness and density of the hair are recovered to be normal, and the hair plucking experiment is (-). The effect is shown: more than 70% of the hair has new growth, the thickness and the color of the hair are close to normal, and the hair plucking experiment is (-). The method is effective: 10% -70% of new hair grows, and no alopecia occurs. Invalidation: after 2 treatment periods, the hair does not grow, or the hair does not grow but falls off.
Comparison of the efficacy of treatment of alopecia areata in each test group
| Group of | n | Has obvious effect | Effective and effective | Invalidation of | Overall efficiency |
| Example 1 group | 30 | 16 | 9 | 5 | 83.3% |
| Example 2 group | 30 | 17 | 8 | 5 | 83.3% |
| Example 3 group | 30 | 16 | 10 | 4 | 86.6% |
| Example 4 group | 30 | 18 | 9 | 3 | 90.0% |
| Comparative example 1 group | 30 | 8 | 10 | 12 | 60.0% |
| Comparative example 2 group | 30 | 6 | 11 | 13 | 56.6% |
| Comparative example 3 group | 30 | 5 | 9 | 16 | 46.6% |
| Comparative example 4 group | 30 | 7 | 8 | 15 | 50.0% |
| Comparative example 5 group | 30 | 8 | 9 | 13 | 56.6% |
| Comparative example 6 group | 30 | 6 | 10 | 14 | 53.3% |
| Comparative example 7 group | 30 | 5 | 8 | 17 | 43.3% |
| Comparative example 8 group | 30 | 7 | 9 | 14 | 53.3% |
| Comparative example 9 group | 30 | 8 | 10 | 12 | 60.0% |
As shown by the experimental results in the table, after the treatment of 2 treatment courses of the medicines for the patients in the groups of examples 1-4, most of the patients grow new hair, and the hair is thick and black, and has no hair loss, so that the symptoms are obviously improved compared with the situation before the administration. The total effective rates of the embodiment 1, the 2, the 3 and the 4 groups are respectively 83.3%, 86.6% and 90.0%, and the total effective rate of the comparative example group is lower as a whole. The formula for treating alopecia areata and promoting burn wound healing prepared by the technical scheme of the invention has obvious treatment effect on treating alopecia areata and burn, and no adverse reaction of the medicines of each experimental group is found in the treatment process.
Claims (1)
1. A traditional Chinese medicine composition for treating alopecia, in particular to a hair tonic prepared from traditional Chinese medicines, which is characterized in that: the preparation method comprises the following steps:
s1, preparing cantharis from liquorice and glutinous rice: soaking 12 g of cantharis with the U-shaped feet removed in a soup prepared by adding 36 g of liquorice into 300ml of water and decocting with slow fire for 30 minutes for 2 hours, picking up cantharis, sun-drying, adding 200 g of glutinous rice into a pot, and parching until the rice is golden yellow, and picking up cantharis;
s2, taking 15-35 parts of dragon' S blood, 15-50 parts of ginkgo leaf, 15-30 parts of Chinese angelica, 20-35 parts of radix codonopsis, 30-60 parts of hedysarum hedysari, 10-35 parts of lithospermum, 12-20 parts of radix angelicae and 10-35 parts of rhizoma drynariae, cleaning, placing into a glass bottle, adding 3-12 parts of cantharis, wherein the mass of each part of medicinal materials in the formula is 1 g, adding 150ml of liquorice water which is used for soaking the cantharis in the original state into 800ml of 75% alcohol, and soaking in a sealing manner for 30 days to obtain a solution 1;
s3, adding 2500mg of cystine tablets into 50ml of sodium bicarbonate solution for soaking, and completely dissolving to obtain solution 2;
s4, mixing the solution 1 and the solution 2 to obtain a hair growth solution, directly and externally applying the hair growth solution, dipping a proper amount of impregnant by using a absorbent cotton ball, lightly applying the liquid to an affected part, generally taking the liquid for 3-5 days by a patient, wherein the scalp is slightly and thinly damaged like bubbles, scabbing after the application is stopped, and growing new hair after the liquid is removed for 10 days, wherein the maximum time is no more than 15 days, 15 days is a treatment course, and the liquid is continuously used for 1-2 treatment courses after the new hair is grown.
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