CN101829263B - Traditional Chinese medicinal composition for treating redness and preparation thereof - Google Patents

Traditional Chinese medicinal composition for treating redness and preparation thereof Download PDF

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Publication number
CN101829263B
CN101829263B CN2010101908364A CN201010190836A CN101829263B CN 101829263 B CN101829263 B CN 101829263B CN 2010101908364 A CN2010101908364 A CN 2010101908364A CN 201010190836 A CN201010190836 A CN 201010190836A CN 101829263 B CN101829263 B CN 101829263B
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red blood
treatment
blood streak
parts
medicine composition
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CN101829263A (en
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贾孝荣
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LANZHOU GUCHI BIOLOGICAL TECHNOLOGY Co Ltd
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LANZHOU GUCHI BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention provides a traditional Chinese medicinal composition for treating redness, which comprises the components of lucid asparagus, moutan bark and red flower and has the effects of nourishing Yin and moistening dryness, cooling and activating blood, clearing away the lung-heat and lowering fire, eliminating stagnant blood and removing redness and maintaining beauty based on the synergism of the components. Proved by dozens of years of research data, the medicinal composition has definite curing and nourishing effects on treating the angiotelectasia, therefore, the composition can be prepared into various preparations for oral administration by adopting conventional processes of the pharmacy of Chinese medicinal herbs.

Description

The Chinese medicine composition and the preparation thereof that are used for the treatment of red blood streak
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicine composition and preparation thereof that is used for the treatment of red blood streak.
Technical background
" red blood streak " is the Northwest, and particularly the very common a kind of dermatosis in rural area medically is " telangiectasia "." red blood streak " mainly is because facial telangiectasis or the shallow facial phenomenon that causes of a part of blood capillary location tables, red blood streak patient face looks redder than the general normal colour of skin, people often claim the plateau face or the egg of blushing, what have only is that both sides cheekbone portion is rubescent, the border is rounded, generally is the silk thread shape and arranges.This skin is thin and responsive, and face is redder when supercool, overheated, excited.Severe patient also can form deposition property mottle, is difficult to cure, and not only influences the beauty of appearance, also can cause shade to psychology, to bringing great inconvenience orthobiosis.Therefore, remove red blood streak and not only be necessary, and extremely urgent.
" red blood streak " clinical manifestation: the general red or blood streak of two cheek exposes, exciting stimulations, tense and stimulation, angry stimulation, cold stimulation, blast stimulation, high temperature stimulate, make up that product stimulate, nursing stimulations, hot water stimulation, cold water stimulating, diet stimulation, oppress stimulation, menstruation is preceding or intermenstrual period or all can increase the weight of in various degree between the onset of ovulation.
The reason that causes " red blood streak " is a lot, is summarized as follows:
1, region telangiectasia: owing to long-term live and work on the plateau, the area of cold, high wind, intensive ultraviolet causes.Main solution at first is to break away from abominable live and work environment, and next is symptomatic treatment according to circumstances.
2, hereditary telangiectasia: prove have 15% telangiectasia and genetic affinity close according to medical research, still do not have better countermeasure at present.
3, physiological telangiectasia: increase and cause telangiectasis owing to factors such as shy, nervous, angry, excitement cause adrenal hormone secretion one to cross property.Generally do not belong to the treatment category.
4, viscera disease telangiectasia: the Secondary cases telangiectasia that causes owing to diseases such as the heart, lungs.Should promptly treat primary disease, after primary disease was cured, this symptom can disappear voluntarily.
5, skin lesion telangiectasia: owing to all can cause skin texture and function to be badly damaged in treatment treatment measure and the too frequent skin nursing that thing or abuse abuse cosmetics or change mistakes such as skin such as decortication of applying medicinal lotion or ointment outside the life-time service hormones during some dermatopathies, skin immunization power is low, telangiectasis.
For the treatment of various " red blood streak ", also be in prevention and nursing stage at present, ineffective especially treatment means and medicine.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition that is used for the treatment of red blood streak.
The pathological change of red blood streak is a stratum corneum gets thinner, is presented on the red netted of face behind the subcutaneous telangiectasis congestion.The principle of therefore, Chinese traditional treatment " red blood streak " is: treat completely from inside to outside and can dispel according to the pathogeny of red blood streak.From interior suitable blood circulation promoting and blood stasis dispelling, remove the blood stasis of blood capillary, from repairing facial horny layer outward, the raising skin barrier function.
It is crude drug that the present invention selects Radix Asparagi, Cortex Moutan, Flos Carthami for use, the effect of each crude drug is played altogether reach the treatment telangiectasia, realizes removing the purpose of red blood streak.
Radix Asparagi has another name called Radix Asparagi, sweet, bitter, Great Cold returns lung, kidney channel, and the lung heat clearing pathogenic fire reducing is nourshing Yin and drynsessmoistening prescription.Be generally used for lung-heat syndrome, consumption of YIN caused by febrile disease card, dryness of the intestine constipation card.This product is gone into lung meridian, and lung governing skin and hair, by controlling lung to control skin; But loosening bowel to relieve constipation again, and the lung and the large intestine being interior-exteriorly related, by relieving constipation to control skin; This product is again the product of long-lived health preserving; But this product YIN nourishing, and the traditional Chinese medical science has " YIN often being in shortage, YANG often being in excess " empirical theory.So this product is used for telangiectasia its distinctive feature is arranged." not Lu ": " Baoding lung qi, cold relieving heat are supported skin ... ".
Cortex Moutan is bitter, hot, be slightly cold GUIXIN, liver, kidney channel, clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Be generally used for warm disease, syndrome of blood stasis, carbuncle sore card.Modern study shows that the effect of the cardiovascular system of adjusting, arteriosclerosis effect, antiinflammatory action, analgesic activity, sedation, adjusting immunization are arranged.Clinical research shows that it can be used for various skin problems such as treatment of allergic rhinitis, urticaria, itching skin disease.Through our clinical research for many years, show that it has good skin reparation and Red blood streak dispelling effect.Compendium of Material Medica: " and blood, hemopoietic, removing heat from blood is controlled the blood fire second of the three ten-day periods of the hot season, heat clearing away and restlessness relieving.”
Flos Carthami, hot, warm, GUIXIN, Liver Channel, stimulate the menstrual flow at blood circulation promoting and blood stasis dispelling.Being generally used for amenorrhea, dysmenorrhea, the not all right, mass in the abdomen of lochia mass in the abdomen, injury from falling down, skin infection swells and ache.Modern pharmacological research proves that it has good regulating action to cardiovascular, blood fat, blood pressure, nervous system, reproductive system, also has effects such as calmness, anti-hypoxia, resisting fatigue, anti-inflammatory, antibacterial.Clinically can be used for phlebitis, local scleroma lump, erythema multiforme, erythema nodosum, injure decubital ulcer, neurodermatitis, verruca plana, allergic rhinitis outward, have not yet to see the treatment document that is useful on telangiectasia, studying it for many years through us has therapeutical effect to this disease.
The present invention is that raw material makes up with Radix Asparagi, Cortex Moutan, Flos Carthami, three's effect is played altogether, nourshing Yin and drynsessmoistening prescription, removing heat from blood and promoting blood circulation, lung heat clearing pathogenic fire reducing, dissipating blood stasis are dispelled red, remove the blood stasis of blood capillary, thereby realize horny layer from outer repair surface portion, improve skin barrier function, to reach the purpose of removing red blood streak.
The mechanism of action of medicine of the present invention is: nourshing Yin and drynsessmoistening prescription, and removing heat from blood and promoting blood circulation, lung heat clearing pathogenic fire reducing, blood circulation promoting and blood stasis dispelling goes the interior blood stasisization of blood capillary, has improved the circulation of blood vessel, the elastic return original state of blood capillary, structure are replied ortho states, thereby make the blood capillary stasis of blood red the moving back of loosing, finally skin of face rehabilitation.
A large amount of tests and clinical summary, each crude drug of Chinese medicine composition of the present invention all has good effect to Red blood streak dispelling in the scope of following weight portion:
5~15 parts of Radix Asparagi, 5~15 parts of Cortex Moutans, 1~10 part on Flos Carthami.
Optimum ratio: 8~12 parts of Radix Asparagi, 8~12 parts of Cortex Moutans, 2~5 parts on Flos Carthami.
Chinese medicine composition of the present invention can be prepared into various oral preparations by the common process and the adjuvant of pharmacy of Chinese materia medica.Oral preparations mainly contains capsule, tablet, granule, powder, pill (comprising the watered pill, honeyed pill, dragee, soft gelatin capsule, enteric coated pill or drop pill), microencapsulation or oral liquid, medicinal tea etc.
Be the clinical trial data that the present invention is used for the treatment of the Chinese medicine composition of red blood streak below:
1. subjects and method:
1.1 tried thing: capsule medicine of the present invention is provided by Gansu Qingdai Chinese Herbal Medicine Beauty Research Co., Ltd..
1.2 study subject:
By the 100 example ages during dissimilar selection nineteen ninety-five~1997 year at 18~53 years old with interior women's red blood streak patient.Region red blood streak 20 examples, heritability red blood streak 20 examples, physiological red blood streak 20 examples, viscera disease red blood streak 20 examples, skin lesion red blood streak 20 examples.
1.3 diagnostic criteria:
Region red blood streak case is from area, Gannan, Gansu, and characteristic of field (anoxia, ultraviolet is strong for high height above sea level, cold) is arranged clearly; The heritability red blood streak then selects father and mother both sides to have a side that red blood streak medical history person is arranged; Physiological red blood streak patient is general, and the age is less; The viscera disease red blood streak generally all has internal disease in various degree to exist, but its protopathy is fully recovered when receiving treatment red blood streak; The skin lesion red blood streak all is because the sequela of other dermatosis and the sequela of malpractice.
1.4 Therapeutic Method:
Take this product capsule 0.3g/ grain, every day three times, each 5,30 days is a course of treatment, 3~6 courses of treatment of overview.Forbid during the treatment doing and change the clean skin of skin art, dermabrasion and deep layer.Eat stimulation food less, prolong 1~2 hour length of one's sleep every day.
2. curative effect is judged:
The whole eliminators of red blood streak are recovery from illness, and eliminating 50% above person is produce effects, and eliminating 30% above person is effectively, and it is invalid eliminating 30% following person.
3. result of the test:
Region patient: 5 examples of fully recovering account for 25%; Produce effects 8 examples account for 40%; Effective 5 examples account for 25%; Invalid 2 examples account for 10%.
Heritability patient: 9 examples of fully recovering account for 45%; Produce effects 5 examples account for 25%; Effective 3 examples account for 15%; Invalid 3 examples account for 15%.
Physiological patient: 16 examples of fully recovering account for 80%; Produce effects 4 examples account for 20%.
The viscera disease patient: 13 examples of fully recovering account for 65%; Produce effects 3 examples account for 15%; Effective 2 examples account for 10%; Invalid 2 examples account for 10%.
The skin lesion patient: 17 examples of fully recovering account for 85%; Produce effects 2 examples account for 10%; Invalid 1 example accounts for 5%.
4. the analysis of statistical data:
Red blood streak treatment complexity is followed successively by: region, heritability, viscera disease, skin lesion, physiological.
5. conclusion:
Above-mentioned clinical experiment shows that medicine of the present invention has telangiectasia clearly treats and take good care of effect.Though it is unbalanced to various red blood streak therapeutic effect, still all effective; To adopt the medicine food homologous raw materials medicine be component in the present invention in addition, and human body is had certain function of health care, has no side effect.
The specific embodiment
The preparation of embodiment 1, tablet medicine of the present invention
Prescription: in weight portion: 10 parts of Radix Asparagi, 10 parts of Cortex Moutans, 3 parts on Flos Carthami.
Technology: the common process and the adjuvant that prepare tablet by pharmacy of Chinese materia medica are prepared into tablet medicine.
The preparation of embodiment 2, capsule medicine of the present invention
Prescription: in weight portion: 8 parts of Radix Asparagi, 8 parts of Cortex Moutans, 2 parts on Flos Carthami.
Technology: the common process and the adjuvant that prepare capsule by pharmacy of Chinese materia medica are prepared into capsule medicine.
The preparation of embodiment 3, powder agent medicine of the present invention
Prescription: in weight portion: 12 parts of Radix Asparagi, 12 parts of Cortex Moutans, 2 parts on Flos Carthami.
Technology: the common process and the adjuvant that prepare powder by pharmacy of Chinese materia medica are prepared into powder agent medicine.
The preparation of embodiment 4, granules medicine of the present invention
Prescription: in weight portion: 10 parts of Radix Asparagi, Cortex Moutan 8~part, 2 parts on Flos Carthami.
Technology: the common process and the adjuvant that prepare granule by pharmacy of Chinese materia medica are prepared into granules medicine.
The preparation of embodiment 5, drop pill medicine of the present invention
Prescription: in weight portion: 12 parts of Radix Asparagi, 10 parts of Cortex Moutans, 2 parts on Flos Carthami.
Technology: the common process and the adjuvant that prepare drop pill by pharmacy of Chinese materia medica are prepared into the drop pill medicine.
The preparation of embodiment 6, watered pill medicine of the present invention
Prescription: in weight portion: 8 parts of Radix Asparagi, 12 parts of Cortex Moutans, 3 parts on Flos Carthami.
Technology: the common process and the adjuvant that prepare watered pill by pharmacy of Chinese materia medica are prepared into the watered pill medicine.
The preparation of embodiment 7, honey pill agent medicine of the present invention
Prescription: in weight portion: 8 parts of Radix Asparagi, 8 parts of Cortex Moutans, 5 parts on Flos Carthami.
Technology: the common process and the adjuvant that prepare honey pill agent by pharmacy of Chinese materia medica are prepared into the honey pill agent medicine.
The preparation of embodiment 8, oral medicine liquid of the present invention
Prescription: in weight portion: 15 parts of Radix Asparagi, 10 parts of Cortex Moutans, 1 part on Flos Carthami.
Technology: the common process and the adjuvant that prepare oral liquid by pharmacy of Chinese materia medica are prepared into oral medicine liquid.
The preparation of embodiment 9, medicinal tea medicine of the present invention
Prescription: in weight portion: 10 parts of Radix Asparagi, 8 parts of Cortex Moutans, 1 part on Flos Carthami.
Technology: the common process and the adjuvant that prepare medicinal tea by pharmacy of Chinese materia medica are prepared into the medicinal tea medicine.

Claims (7)

1. Chinese medicine composition that is used for the treatment of red blood streak is to be crude drug with Radix Asparagi, Cortex Moutan, Flos Carthami, the oral preparations that is prepared into by the common process and the adjuvant of pharmaceutics;
Described each raw material carries out proportioning by following weight portion:
8~12 parts of Radix Asparagi, 8~12 parts of Cortex Moutans, 2~5 parts on Flos Carthami.
2. be used for the treatment of the Chinese medicine composition of red blood streak according to claim 1, it is characterized in that: described preparation is a powder.
3. be used for the treatment of the Chinese medicine composition of red blood streak according to claim 1, it is characterized in that: described preparation is a tablet.
4. be used for the treatment of the Chinese medicine composition of red blood streak according to claim 1, it is characterized in that: described preparation is a capsule.
5. be used for the treatment of the Chinese medicine composition of red blood streak according to claim 1, it is characterized in that: described preparation is a pill.
6. be used for the treatment of the Chinese medicine composition of red blood streak according to claim 1, it is characterized in that: described preparation is an electuary.
7. be used for the treatment of the Chinese medicine composition of red blood streak according to claim 1, it is characterized in that: described preparation is a medicinal tea.
CN2010101908364A 2010-05-29 2010-05-29 Traditional Chinese medicinal composition for treating redness and preparation thereof Active CN101829263B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1546077A (en) * 2003-12-05 2004-11-17 玲 王 Blood streak removing medicine
CN1943714A (en) * 2006-10-16 2007-04-11 中国人民解放军第三医院 A medicine for treatment of red blood streak

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1546077A (en) * 2003-12-05 2004-11-17 玲 王 Blood streak removing medicine
CN1943714A (en) * 2006-10-16 2007-04-11 中国人民解放军第三医院 A medicine for treatment of red blood streak

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