CN101897868B - Chinese medicinal composition for treating psoriasis and preparation method thereof - Google Patents

Chinese medicinal composition for treating psoriasis and preparation method thereof Download PDF

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CN101897868B
CN101897868B CN2010102121290A CN201010212129A CN101897868B CN 101897868 B CN101897868 B CN 101897868B CN 2010102121290 A CN2010102121290 A CN 2010102121290A CN 201010212129 A CN201010212129 A CN 201010212129A CN 101897868 B CN101897868 B CN 101897868B
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psoriasis
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赵子山
赵金环
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赵子山
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Abstract

The invention relates to a Chinese medicinal composition for treating psoriasis and a preparation method thereof. The Chinese medicinal composition comprises glabrous greenbrier rhizome, parsnip, bark of tree peony root, indigowoad leaf, baical skullcap root, dense-fruit pittany root-bark, sophora flower, root of red-rooted salvia, Chinese angelica, red paeony root, rehmannia root, stiff silkworm, garter snake, scorpion and honeysuckle. The Chinese medicinal composition has reasonable compatibility, can be prepared into various clinically suitable external preparations such as lotion, ointment, embrocation and the like according to a Chinese medicinal conventional preparation method, and particularly can relieve or control the development of the psoriasis by adopting Chinese medicinal balneotherapy, reduce the relapse frequency of the psoriasis, prolong the remission period, reduce the toxic or side effect of western medicament, improve the psychological or social living quality of patients and improve the quality of life.

Description

一种治疗银屑病的中药组合物及其制备方法 A method of treating psoriasis Chinese medicine and its preparation method

技术领域 FIELD

[0001] 本发明涉及一种中药组合物,尤其涉及一种治疗银屑病的中药组合物,本发明还涉及该中药组合物的制备方法,属于中药领域。 [0001] The present invention relates to a traditional Chinese medicine composition, more particularly to a traditional Chinese medicine composition for treating psoriasis, the present invention also relates to a method for preparing the traditional Chinese medicine composition, which belongs to the field of medicine.

背景技术 Background technique

[0002] 银屑病(Psoriasis),俗称牛皮癣,中医古称之为“白庀”,古医籍亦有称之为松皮癣,是一种常见的慢性皮肤病,其特征是出现大小不等的丘疹,红斑,表面覆盖着银白色鳞屑,边界清楚,好发于头皮、四肢伸侧及背部。 [0002] Psoriasis (Psoriasis), commonly known as psoriasis, the ancient Chinese called "White Pi", also known as pine bark Ancient Medical ringworm, is a common chronic skin disease, characterized by the emergence of varying sizes pimples, erythema, and covered with silvery white scales, clear boundary, occur in the scalp, extensor limbs and back. 男性多于女性。 More men than women. 春冬季节容易复发或加重,而夏秋季多缓解。 Spring Festival is easy to relapse or worsen in winter, while summer and autumn and more ease. 其病因尚不清楚,也无一种药物能达到根治。 Its cause is not yet clear, but also to achieve a drug-free cure. 许多患者在治疗牛皮癣时由于没有遵循用药要求,不仅没有改善疾病症状,反而错过了最佳的牛皮癣治疗时机,治疗牛皮癣一定要在专家的指导下合理用药。 Many patients in the treatment of psoriasis since there is no follow medication requirements, not only did not improve symptoms of the disease, but missed the best time for treatment of psoriasis, psoriasis treatment medication must be reasonable under the guidance of experts.

[0003] 牛皮癣的治疗时间比较长,目前对于牛皮癣的治疗西医方面大部分的治疗是采用外用药膏或者其他的一些免疫制剂等来治疗牛皮癣,这些治疗见效快但只是针对病症的治疗,没有针对病灶根源去采取治疗方法。 [0003] psoriasis treatment a long time now for most of Western medicine treatment of psoriasis treatment is the use of topical creams or some other immune agents such as the treatment of psoriasis, but only for a quick treat these disorders treatment, there are no lesions root cause to take treatment. 所以,在遇到外界的诱因的情况下仍会复发。 So, it will relapse in the case of having the outside world incentives.

[0004] 中医学在现代医学治疗牛皮癣方面占有重要的地位,有着丰富的治疗经验,已得到越来越多人的认可,其疗效的长远、副作用小,赢得了很多患者的好评。 [0004] Chinese medicine plays in modern medicine treatment of psoriasis aspects important position, has a wealth of experience in the treatment, has been recognized by more and more people, the long-term, side effects of its efficacy, won the praise of many patients. 中医常用的牛皮癣治疗方法,例如1)养血润燥法:皮疹常见有干燥、脱屑、皲裂、革化等特点,属于燥的牛皮癣患者,应该用当归、地黄、元参、麦冬、白芍、首乌、胡麻仁药物治疗;2)清热解毒法:皮疹常有红热肿痛的特点,属于热的牛皮癣患者,常用药物有二花、黄芩、黄柏、黄连、野菊花、蒲公英;3)活血化瘀法:皮疹具有色素增加紫斑,出现暗红色结节等特点,属于血瘀的牛皮癣患者,其常用药物有当归、桃仁、红花、赤芍、丹皮等药物。 Commonly used Chinese medicine treatment of psoriasis, for example, 1) method nourishing and moistening: rash common with dry, scaling, chapped, leather, and other characteristics, belonging to dry psoriasis patients should Angelica, Huang, Yuan ginseng, Radix, white Shao, Radix, Maren medications; 2) detoxification method: heat rash often red swelling characteristics of patients with psoriasis is hot, there are two commonly used drugs flowers, Scutellaria, Phellodendron, Coptis, chrysanthemum, dandelion; 3 ) Blood circulation: purple rash has increased pigmentation, appear dark red nodules and other characteristics of psoriasis patients belong to blood stasis, the commonly used drugs Angelica, peach kernel, safflower, red peony, Dan and other drugs. 而大多中医是针对血热、血瘀和消除肝火旺的治疗,这种治疗能起到效果,但是这种治疗所用的清热解毒或者是脏腑调理的药物,不能对牛皮癣的病根起到作用。 The Chinese medicine is mostly for blood heat, blood stasis and eliminating anger Wang's treatment, this treatment effect can play, but this detoxification treatment used drugs or viscera conditioning can not play a role on the root cause of psoriasis.

发明内容 SUMMARY

[0005] 本发明的目的在于提供一种治疗银屑病的中药组合物及其制备方法,通过合理配伍,对各种原因引起的银屑病达到确实治疗和明显改善的效果。 [0005] The object of the present invention is to provide a method of treating psoriasis Chinese medicinal composition and its preparation, by reasonable compatibility, psoriasis various causes and treatment of actually achieve significantly improved.

[0006] 为了达到上述目的,本发明采用如下的技术方案: [0006] To achieve the above object, the present invention adopts the following technical solution:

[0007] —种治疗银屑病的中药组合物,其特征在于包括以下原料药:土茯苓、防风、牡丹皮、大青叶、黄芩、白鲜皮、槐花、丹参、当归、赤芍、生地黄、僵蚕、乌梢蛇、全蝎和金银花。 [0007] - medicine psoriasis therapeutic composition comprising the drug: Smilax, wind, Cortex Moutan, Folium, skullcap, fresh white skin, Sophora japonica, Salvia, angelica, peony, Rehmanniae, silkworm, black snake, scorpion and honeysuckle.

[0008] 各原料药的重量配比为:土茯苓20-40份、防风5-25份、牡丹皮5_25份、大青叶20-40份、黄芩5-25份、白鲜皮10-30份、槐花5_25份、丹参10-30份、当归5_25份、赤芍5-25份、生地黄5-25份、僵蚕5-20份、乌梢蛇5_20份、全蝎5_20份、金银花5_20份。 [0008] Each of the weight ratio of drug: 20-40 parts Smilax, wind 5-25, Cortex Moutan 5_25 parts, 20-40 parts Folium, scutellaria 5-25, 10-30 Dictamni copies, SJ 5_25 parts, 10-30 parts of Salvia, Angelica 5_25 part, TPG 5-25 REHMANNIAE 5-25, 5-20 parts silkworm, black snake 5_20 part, Scorpio 5_20 copies, honeysuckle 5_20 copies.

[0009] 优选各原料药的重量配比为:土茯苓25-35份、防风10-20份、牡丹皮10_20份、大青叶25-35份、黄芩10-20份、白鲜皮15-25份、槐花10-20份、丹参15-25份、当归10-20 份、赤芍10-20份、生地黄10-20份、僵蚕5-15份、乌梢蛇5_15份、全蝎5_15份、金银花5_15份。 [0009] Preferably, the weight ratio of each API: Smilax 25-35 parts, 10-20 parts by wind, Cortex Moutan 10_20 parts, Folium 25-35 parts, 10-20 parts of Scutellaria, 15 Dictamni 25 parts, SJ 10-20, 15-25 parts salvia, angelica 10-20, 10-20 TPG, REHMANNIAE 10-20, 5-15 parts silkworm, black snake 5_15 parts, whole scorpion 5_15 parts, honeysuckle 5_15 copies.

[0010] 更优选各原料药的重量配比为:土茯苓30份、防风15份、牡丹皮15份、大青叶30 份、黄芩15份、白鲜皮20份、槐花15份、丹参20份、当归15份、赤芍15份、生地黄15份、 僵蚕10份、乌梢蛇10份、全蝎10份、金银花10份。 [0010] More preferably the respective weight ratio of the drug: Smilax 30 parts, 15 parts of wind, Cortex Moutan 15 parts, 30 parts Folium, skullcap 15 parts, 20 parts of fresh white skin, 15 parts of Sophora japonica, Salvia 20 parts, 15 parts of angelica, red peony 15 parts REHMANNIAE 15 parts, 10 parts of silkworm, 10 parts of black snake, scorpion 10 parts, 10 parts of honeysuckle.

[0011] 本发明中以牡丹皮、当归、丹参、赤芍开血中之壅滞,养血活血、凉血通络,改善银屑病患者的皮肤血液循环,降低血液粘稠度,减少患者血管的通透性。 [0011] In the present invention, Cortex Moutan, Angelica, Salvia, Radix open the blood stasis, nourishing blood, cooling meridians, improve skin blood circulation psoriasis patients, reduce blood viscosity, reduce patient vascular permeability. 以土茯苓、大青叶、黄芩、槐花、生地、金银花清热利湿、解毒杀虫、清络中风火湿热,能够使表皮细胞增殖减慢,减轻皮损的发展,以防风、白鲜皮祛风止痒,以白僵蚕、乌梢蛇、全蝎等虫类药物,通络搜风以毒攻毒杀虫止痒,全方共奏活血化瘀、清热凉血、化湿解毒、祛风止痒、剔毒搜风的功效。 In Smilax, Folium, skullcap, SJ, habitat, honeysuckle heat and dampness, insecticide detoxification, wind, fire, the heat Qingluo, possible to slow down the proliferation of epidermal cells, reducing the development of lesions, to wind, Dictamni chills and itching, silkworm white, black snake, scorpion drugs and other insects, fire with fire meridians insecticidal itching found the wind, the whole side played blood circulation, Qingreliangxue, dampness detoxification, Qufeng itch, found the wind tick toxic effect.

[0012] 本发明所用到的原料药均可从普通中药材商店购买得到,其规格符合国家中药材标准即可。 [0012] The raw material used in the present invention can be purchased to get the drug from ordinary Chinese herbal medicine shops, and its specifications in line with national standards of Chinese herbal medicines can be.

[0013] 本发明中药组合物可以选择性地加入制备不同剂型时所需的各种辅料,例如崩解剂、润滑剂、黏合剂等,以常规的中药制剂方法制备成任何一种外用制剂;所述的外用制剂可以是洗剂、软膏剂、擦剂等。 [0013] The herbal composition of the present invention may optionally be added to the various materials required for the preparation of different dosage forms, e.g. disintegrants, lubricants, binders and the like, external preparation prepared into any conventional formulation methods medicine; the topical formulation may be a lotion, ointment, liniment and the like.

[0014] 本发明的另一个目的是提供制备本发明中药组合物的方法,包括如下步骤: [0014] Another object of the present invention is to provide a preparation of the herbal composition of the present invention, comprising the steps of:

[0015] (1)按重量份数称取各原料药; [0015] (1) parts by weight of the respective raw materials weighed drug;

[0016] (2)将上述中药混合在一起后,置于砂锅内,加水没过药面,浸泡20-40分钟后,再煎煮,煮沸后再续煎30分钟,共煎煮3次;合并3次煎液过滤,得到洗剂。 [0016] (2) After the above-described medicine were mixed together, placed in a casserole, add water over Emulsion, soak for 20-40 min, then boiling, boiled for 30 minutes after boiling adjourned, were boiled with 3 times; The combined decoction was filtered three times, to give a lotion.

[0017] 本发明还提供一种制备本发明中药组合物的方法,包括如下步骤: [0017] The present invention further provides a method of preparing the herbal composition of the present invention, comprising the steps of:

[0018] (1)按重量份数称取各原料药; [0018] (1) parts by weight of the respective raw materials weighed drug;

[0019] (2)将上述中药晒干粉碎过120目筛,混合后得到药粉放置备用; [0019] (2) The above medicine dried crushed through a 120 mesh sieve to give mixed powder is placed back;

[0020] (3)取白凡士林300-500份置水浴加热至熔化,再取甘油30_50份徐徐加入,凉冷后即为软膏辅料备用; [0020] (3) take the white petrolatum 300-500 parts water bath heated to melt, then take 30_50 parts glycerin was added slowly, after cool or cold standby ointment materials;

[0021] (4)取辅料加温熔化,再将步骤(2)的药粉在搅拌下徐徐加入,自然凉后即成软膏剂。 [0021] (4) take the materials heated to melt the powder and then step (2) is gradually added under stirring, an ointment Serve after cool naturally.

[0022] 本发明中药组合物的用法与用量:1)将洗剂的药液倒入浴盆的热水中,趁热遍洗全身,每次洗浴30-40分钟,一日一次,10次为1个疗程;2)取软膏剂,每日按皮损范围涂擦3次,早中晚各1次,15天为1疗程,直至局部病灶消失。 [0022] Dosage of the herbal composition of the present invention: 1) A lotion of the liquid into the hot water bath, hot over the body wash, a bath every 30-40 minutes, once a day, 10 times as a course; 2) to take an ointment, rubbed daily by skin lesions three times, once early in the evening, for a course of 15 days, until local lesions disappeared.

[0023] 本发明中药组合物,尤其洗剂配合中药洗浴疗法,可使中药通过皮肤粘膜,角质层转运,和表皮深层转运而直接进入血液循环吸收利用,减少中药对胃黏膜的损伤刺激,增加中药的药物反应,并通过药浴刺激可使局部血管扩张,促进血液循环,改善周围组织营养, 增强神经反射激发机体的自身调节作用,促使机体某些抗体的形成,从而达到调整脏腑的功能,改善患者体质,迅速改善症状。 [0023] The herbal composition of the present invention, in particular with a lotion balneotherapy medicine, medicine through the skin and mucous membranes can, transport the stratum corneum, epidermis and deep transported directly into the blood circulation and absorption, to reduce the damage of gastric mucosa irritation medicine, increasing drugs of Chinese reaction, by dipping and can stimulate local vasodilation, promotion of blood circulation, improve nutrition surrounding tissue, enhance the body's own regulatory stimulate the reflex action, certain antibodies promote the formation of the body, so as to achieve the function of adjusting the internal organs, improve patient physique, the rapid improvement of symptoms. 减轻或控制银屑病的发展,减少银屑病的复发频率,延长缓解期,并减少西药的毒副作用,改善患者的心理或社会生活质量,提高生存质量。 Reduce or control the development of psoriasis, reduce the frequency of recurrence of psoriasis, toxic side effects of prolonged remission and reduce medicine and improve the quality of psychological or social life of patients and improve the quality of life.

具体实施方式 Detailed ways

[0024] 下面结合具体实施例来进一步描述本发明,本发明的优点和特点将会随着描述而更为清楚。 [0024] The following specific examples further describe the present invention in conjunction with, advantages, and features of the invention will become apparent as the description. 但这些实施例仅是范例性的,并不对本发明的范围构成任何限制。 However, these examples are merely exemplary, and does not constitute any limitation on the scope of the invention. 本领域技术人员应该理解的是,在不偏离本发明的精神和范围下可以对本发明技术方案的细节和形式进行修改或替换,但这些修改和替换均落入本发明的保护范围内。 Those skilled in the art will appreciate that modifications or substitutions can be made in the form and details of the technical solutions of the present invention without departing from the spirit and scope of the present invention, but such modifications and alterations fall within the scope of the present invention.

[0025] 实施例1洗剂的制备 Example 1 Preparation of lotions [0025] Embodiment

[0026] (1)按以下重量称取各原料药:土茯苓30g、防风15g、牡丹皮15g、大青叶30g、黄芩15g、白鲜皮20g、槐花15g、丹参20g、当归15g、赤芍15g、生地黄15g、僵蚕10g、乌梢蛇10g、全蝎10g、金银花IOgo [0026] (1), said weight taken following each drug: Smilax 30g, wind 15g, Cortex Moutan 15g, Folium 30g, Scutellaria 15g, fresh white skin 20g, SJ 15g, Salvia 20g, angelica 15g, red Shao 15g, Rehmanniae 15g, silkworm 10g, black snake 10g, Scorpio 10g, honeysuckle IOgo

[0027] (2)将上述中药混合在一起后,置于砂锅内,加水没过药面,浸泡30分钟后,再煎煮,煮沸后再续煎30分钟,共煎煮3次;合并3次煎液过滤,得到洗剂。 [0027] (2) After the above-described medicine were mixed together, placed in a casserole, add water over Emulsion, soak for 30 minutes, then boiling, frying adjourned after boiling for 30 minutes a total of three times boiling; combined 3 times decoction was filtered to give a lotion.

[0028] 实施例2洗剂的制备 Example 2 Preparation of lotions [0028] Embodiment

[0029] (1)按以下重量称取各原料药:土茯苓25g、防风10g、牡丹皮10g、大青叶25g、黄芩10g、白鲜皮15g、槐花10g、丹参15g、当归10g、赤芍10g、生地黄10g、僵蚕5g、乌梢蛇5g、 全蝎5g、金银花5g。 [0029] (1), said weight taken following each drug: Smilax 25g, wind 10g, Cortex Moutan 10g, Folium 25g, Scutellaria 10g, fresh white skin 15g, SJ 10g, Salvia 15g, angelica 10g, red Shao 10g, Rehmanniae 10g, silkworm 5g, black snake 5g, Scorpio 5g, honeysuckle 5g.

[0030] (2)将上述中药混合在一起后,置于砂锅内,加水没过药面,浸泡20分钟后,再煎煮,煮沸后再续煎30分钟,共煎煮3次;合并3次煎液过滤,得到洗剂。 [0030] (2) After the above-described medicine were mixed together, placed in a casserole, add water over Emulsion, soak for 20 minutes, then boiling, frying adjourned after boiling for 30 minutes a total of three times boiling; combined 3 times decoction was filtered to give a lotion.

[0031] 实施例3洗剂的制备 Example 3 Preparation of lotions [0031] Embodiment

[0032] (1)按以下重量称取各原料药:土茯苓35g、防风20g、牡丹皮20g、大青叶35g、黄芩20g、白鲜皮25g、槐花20g、丹参25g、当归20g、赤芍20g、生地黄20g、僵蚕15g、乌梢蛇15g、全蝎15g、金银花15g。 [0032] (1), said weight taken following each drug: Smilax 35g, wind 20g, Cortex Moutan 20g, Folium 35g, Scutellaria 20g, fresh white skin 25g, SJ 20g, Salvia 25g, angelica 20g, red Shao 20g, Rehmanniae 20g, silkworm 15g, black snake 15g, Scorpio 15g, honeysuckle 15g.

[0033] (2)将上述中药混合在一起后,置于砂锅内,加水没过药面,浸泡40分钟后,再煎煮,煮沸后再续煎30分钟,共煎煮3次;合并3次煎液过滤,得到洗剂。 [0033] (2) After the above-described medicine were mixed together, placed in a casserole, add water over Emulsion, soak for 40 minutes and then boiling, frying adjourned after boiling for 30 minutes a total of three times boiling; combined 3 times decoction was filtered to give a lotion.

[0034] 实施例4软膏剂的制备 Example 4 Preparation of ointment [0034] Embodiment

[0035] (1)按以下重量称取各原料药:土茯苓40g、防风25g、牡丹皮25g、大青叶40g、黄芩25g、白鲜皮30g、槐花25g、丹参30g、当归25g、赤芍25g、生地黄25g、僵蚕20g、乌梢蛇20g、全蝎20g、金银花20g。 [0035] (1), said weight taken following each drug: Smilax 40g, wind 25g, Cortex Moutan 25g, Folium 40g, Scutellaria 25g, fresh white skin 30g, SJ 25g, Salvia 30g, angelica 25g, red Shao 25g, Rehmanniae 25g, silkworm 20g, black snake 20g, Scorpio 20g, honeysuckle 20g.

[0036] (2)将上述中药晒干粉碎过120目筛,混合后得到药粉放置备用; [0036] (2) The above medicine dried crushed through a 120 mesh sieve to give mixed powder is placed back;

[0037] C3)取白凡士林450g置水浴加热至熔化,再取甘油50g徐徐加入,凉冷后即为软膏辅料备用; [0037] C3) Take 450g white petrolatum heated to melt in a water bath, and then take 50g of glycerin were added slowly, after cool or cold standby ointment materials;

[0038] (4)取辅料加温熔化,再将步骤(2)的药粉在搅拌下徐徐加入,自然凉后即成软膏剂。 [0038] (4) take the materials heated to melt the powder and then step (2) is gradually added under stirring, an ointment Serve after cool naturally.

[0039] 实施例5软膏剂的制备 Example 5 Preparation of ointment [0039] Embodiment

[0040] (1)按以下重量称取各原料药:土茯苓20g、防风5g、牡丹皮5g、大青叶20g、黄芩5g、白鲜皮10g、槐花5g、丹参10g、当归5g、赤芍5g、生地黄5g、僵蚕5g、乌梢蛇5g、全蝎5g、 金银花5g。 [0040] (1), said weight taken following each drug: Smilax 20g, wind 5g, Cortex Moutan 5g, Folium 20g, Scutellaria 5g, fresh white skin 10g, Sophora japonica 5g, Salvia 10g, Angelica 5g, red Shao 5g, REHMANNIAE 5g, silkworm 5g, black snake 5g, Scorpio 5g, honeysuckle 5g.

[0041] (2)将上述中药晒干粉碎过120目筛,混合后得到药粉放置备用; [0041] (2) The above medicine dried crushed through a 120 mesh sieve to give mixed powder is placed back;

[0042] C3)取白凡士林360g置水浴加热至熔化,再取甘油40g徐徐加入,凉冷后即为软膏辅料备用; [0042] C3) Take 360g white petrolatum heated to melt in a water bath, and then take 40g of glycerin were added slowly, after cool or cold standby ointment materials;

[0043] (4)取辅料加温熔化,再将步骤O)的药粉在搅拌下徐徐加入,自然凉后即成软膏剂。 [0043] (4) take the materials heated to melt, then step O) powder is slowly added under stirring, an ointment Serve after cool naturally.

[0044] 实验例1 [0044] Experimental Example 1

[0045] 经2003年至2006年间,用本发明药物组合物治疗银屑病的年龄从8岁到50岁不等。 [0045] by 2003 to 2006, the age of the treatment of psoriasis with the pharmaceutical composition of the invention ranging from 8 years old to 50 years old. 根据病症的不同,采用中医辨证论治,将本发明实施例1-5药物组合物制备成的洗剂和/或软膏剂进行治疗,治疗结果:共治疗48例,痊愈42例,占87. 5%,有效5例,占6. 4%, 无效1例,占2. 1%,总有效率为97.9%。 Depending on conditions, the use of syndrome differentiation, lotions prepared in Example 1-5 into a pharmaceutical composition and / or the ointment embodiment of the present invention for treatment, treatment results: 48 patients were treated, cured 42 cases, accounting for 87.5% , 5 cases, accounting for 6.4%, 1 patient, accounting for 2.1%, the total effective rate was 97.9%.

[0046] 特举几例病人如下: [0046] For a few patients Laid follows:

[0047]病例 1 [0047] Case 1

[0048] 黄某,男,14岁,湖南籍。 [0048] Hwang, male, 14 years old, from Hunan Province. 满身红疹、脱屑,重度瘙痒,诊断为银屑病,曾到多处看病治疗未能治愈。 Covered with rash, scaling, severe itching, a diagnosis of psoriasis, many went to see a doctor treatment failed to cure. 采用本发明实施例1洗剂倒入浴盆的热水中,趁热遍洗全身,每次洗浴30-40分钟,一日一次,两日后瘙痒明显减轻,10次即一个疗程后背部胸腹部全部治愈,继续治疗一个疗程后痊愈,随访无复发。 Using the lotion of Example 1 of the present invention in hot water into the tub, washing over the hot body, bath every 30-40 minutes, once a day, two days significantly reduced itching, i.e. 10 times back after a course of the chest and abdomen all cure, cured after a course of treatment to continue follow-up without recurrence.

[0049] 病例2 [0049] Case 2

[0050] 高某,女,8岁,湖南籍。 [0050] high, female, 8 years old, Hunan Province. 全身起脓疱,可自行消退,再发新脓疱,瘙痒疼痛难忍,患病10月余。 Since the body pustules, be self-limiting, and then send the new pustules, itching pain, sick 10 more than a month. 诊断为银屑病。 A diagnosis of psoriasis. 采用本发明实施例2洗剂倒入浴盆的热水中,趁热遍洗全身,每次洗浴30-40分钟,一日一次,三日后脓疱消退,其他症状开始缓解,10次即一个疗程后痊愈, 随访无复发。 2 embodiment of the present invention using the detergent into the tub of hot water, hot over the body wash, a bath every 30-40 minutes, once a day, three days pustules subsided, other symptoms began to ease, i.e., a course 10 after recovery, follow-up without recurrence.

[0051]病例 3 [0051] Case 3

[0052] 张某,男二4岁,湖南籍。 [0052] Zhang, male and two 4-year-old from Hunan Province. 患病八余年,间断治疗过多次,尝试多种外用药物无效; 皮损处斑疹潮红,大量脱屑,瘙痒剧烈,诊断为银屑病。 Sick eight years, intermittent treatment several times, try a variety of topical drugs ineffective; lesions of the rash flushing, a large number of scaling, itching, a diagnosis of psoriasis. 采用本发明实施例3洗剂倒入浴盆的热水中,趁热遍洗全身,每次洗浴30-40分钟,一日一次,10次为1个疗程,治疗两个疗程痊愈,至今无复发。 3 embodiment of the present invention using the detergent into the tub of hot water, hot over the body wash, a bath every 30-40 minutes, once a day, 10 times for a course of treatment, two courses of treatment cured, without recurrence .

[0053]病例 4 [0053] Case 4

[0054] 陈某,男,46岁,湖南籍。 [0054] Chen, male, 46 years old, from Hunan Province. 有大面积红疹、红斑,脱屑严重,尝试多种内服外用药物, 症状虽有时缓解但始终未能治愈。 There are large areas of rash, erythema, scaling serious, try a variety of oral topical drugs, although the symptoms remission but has failed to cure. 诊断为银屑病。 A diagnosis of psoriasis. 采用本发明实施例4软膏剂,每日按皮损范围涂擦3次,早中晚各1次,五日后各种症状开始缓解,15天为1疗程并配合实施例1 的洗剂,连续治疗四个疗程痊愈,至今无复发。 4 embodiment the present invention is an ointment, rubbed daily by skin lesions three times, once early in the evening, after five days to alleviate symptoms began, and 15 days for a course of treatment with the lotion in Example 1, continuous four courses of treatment cured, so far no recurrence.

[0055]病例 5 [0055] Case 5

[0056] 田某,女,38岁,湖南籍。 [0056] Tian, ​​female, 38 years old, from Hunan Province. 患病十余年,皮损大量脱屑、破裂,以上肢和脸部为重。 Sick more than ten years, a large number of scaling skin lesions, breaks for upper limbs and face as the most important. 诊断为银屑病。 A diagnosis of psoriasis. 采用本发明实施例5软膏剂,每日按皮损范围涂擦3次,早中晚各1次,15天为1疗程,一个疗程后脸部明显好转,治疗三个疗程痊愈,随访无复发。 5 embodiment of the present invention using ointments, skin lesions rubbed daily press three times, once early in the evening, for a course of 15 days, a significant improvement after treatment of the face, three courses of treatment cured, follow no recurrence .

Claims (8)

1. 一种治疗银屑病的中药组合物,其特征在于由以下重量份的原料药制成:土茯苓20-40份、防风5-25份、牡丹皮5-25份、大青叶20-40份、黄芩5_25份、白鲜皮10-30份、槐花5-25份、丹参10-30份、当归5-25份、赤芍5_25份、生地黄5_25份、僵蚕5_20份、乌梢蛇5-20份、全蝎5-20份、金银花5-20份。 1. A method of treating psoriasis in a traditional Chinese medicine composition, characterized in that the parts made of the following weight drug: 20-40 parts Smilax, wind 5-25, 5-25 Cortex Moutan, Folium 20 -40 parts, scutellaria 5_25 parts, 10-30 parts of fresh white skin, SJ 5-25, 10-30 parts of Salvia, angelica 5-25, parts of Radix 5_25, 5_25 Rehmanniae parts, silkworm 5_20 parts, 5-20 parts black snake, scorpion 5-20 parts, 5-20 parts of honeysuckle.
2.根据权利要求1所述的治疗银屑病的中药组合物,各原料药的重量配比为:土茯苓25-35份、防风10-20份、牡丹皮10-20份、大青叶25-35份、黄芩10-20份、白鲜皮15-25 份、槐花10-20份、丹参15-25份、当归10-20份、赤芍10-20份、生地黄10-20份、僵蚕5_15 份、乌梢蛇5-15份、全蝎5-15份、金银花5-15份。 The treatment of psoriasis according to traditional Chinese medicine composition as claimed in claim 1, each by weight ratio of the drug: Smilax 25-35 parts, 10-20 parts by wind, 10-20 parts of Cortex Moutan, Folium 25-35 parts, 10-20 parts skullcap, Dictamni 15-25 parts, 10-20 parts of Sophora japonica, Salvia 15-25 parts, 10-20 parts angelica, 10-20 parts of Radix Rehmanniae 10-20 parts, silkworm 5_15 copies, 5-15 parts black snake, scorpion 5-15 parts, honeysuckle 5-15 copies.
3.根据权利要求2所述的治疗银屑病的中药组合物,各原料药的重量配比为:土茯苓30份、防风15份、牡丹皮15份、大青叶30份、黄芩15份、白鲜皮20份、槐花15份、丹参20 份、当归15份、赤芍15份、生地黄15份、僵蚕10份、乌梢蛇10份、全蝎10份、金银花10份。 The treatment of psoriasis according to traditional Chinese medicine composition as claimed in claim 2, the weight ratio of each API: Smilax 30 parts, 15 parts of wind, Cortex Moutan 15 parts, 30 parts Folium, skullcap 15 parts , 20 parts of fresh white skin, Sophora japonica 15 parts, 20 parts of Salvia, angelica 15 parts, 15 parts of Radix Rehmanniae 15 parts, 10 parts of silkworm, 10 parts of black snake, scorpion 10 parts, 10 parts of honeysuckle.
4.根据权利要求1-3任一项所述的治疗银屑病的中药组合物,以常规的中药制剂方法制备成任何一种外用制剂。 4. The herbal composition for treating psoriasis according to any of claims 1-3, prepared into any formulations in conventional external preparation methods medicine.
5.根据权利要求4所述的治疗银屑病的中药组合物,所述的外用制剂是洗剂、软膏剂或擦剂。 The treatment of psoriasis herbal composition as claimed in claim 4, wherein said formulation is a topical lotions, ointments or liniments.
6. 一种制备权利要求1-3任一项所述治疗银屑病的中药组合物的方法,包括如下步骤:(1)按重量份称取各原料药;(2)将上述中药混合在一起后,置于砂锅内,加水没过药面,浸泡20-40分钟后,再煎煮,煮沸后再续煎30分钟,共煎煮3次;合并3次煎液过滤,得到洗剂。 The method of any of claims 1-3 traditional Chinese medicine composition A process for preparing a claim for treating psoriasis, comprising the steps of: (1) parts by weight of the raw materials weighed drug; (2) mixing the medicine in the after together and placed in a casserole, add water over Emulsion after soaking for 20-40 minutes, then boiling, boiled for 30 minutes after boiling adjourned, a total of three times boiling; 3 combined decoction was filtered to give a lotion.
7. 一种制备权利要求1-3任一项所述治疗银屑病的中药组合物的方法,包括如下步骤:(1)按重量份称取各原料药;(2)将上述中药晒干粉碎过120目筛,混合后得到药粉放置备用;(3)取白凡士林300-500份置水浴加热至熔化,再取甘油30-50份徐徐加入,凉冷后即为软膏辅料备用;(4)取辅料加温熔化,再将步骤(2)的药粉在搅拌下徐徐加入,自然凉后即成软膏剂。 The method of the traditional Chinese medicine composition according to any one 1-3 A preparation as claimed in claim treating psoriasis, comprising the steps of: (1) parts by weight of the raw materials weighed drug; (2) The above medicine dried sifted through a 120 mesh sieve to give mixed powder is placed standby; (3) take the white petrolatum 300-500 parts water bath heated to melt, then take 30 to 50 parts of glycerin was added slowly, after cool or cold standby ointment materials; (4 ) was warmed to melt materials taken, then the powder of step (2) was added slowly with stirring, cool the natural Serve ointments.
8.权利要求1-5任一项所述的治疗银屑病的中药组合物在制备治疗银屑病的药物中的用途。 The treatment of psoriasis medicine composition according to any of claims 1-5 in the manufacture use of a medicament the treatment of psoriasis of claim.
CN2010102121290A 2010-06-28 2010-06-28 Chinese medicinal composition for treating psoriasis and preparation method thereof CN101897868B (en)

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