CN103637202B - Rhizoma dioscoreae-radix astragali-poria cocos chewable tablets and preparation method - Google Patents

Rhizoma dioscoreae-radix astragali-poria cocos chewable tablets and preparation method Download PDF

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CN103637202B
CN103637202B CN201310665440.4A CN201310665440A CN103637202B CN 103637202 B CN103637202 B CN 103637202B CN 201310665440 A CN201310665440 A CN 201310665440A CN 103637202 B CN103637202 B CN 103637202B
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chinese yam
radix astragali
poria cocos
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CN103637202A (en
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罗永祺
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Nantong Xiang Xiang biological medicine technology Co., Ltd.
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罗永祺
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/10Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/20Agglomerating; Granulating; Tabletting
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention discloses rhizoma dioscoreae-radix astragali-poria cocos chewable tablets which comprise the following components in parts by weight: 7-13 parts of rhizoma dioscoreae, 7-13 parts of radix astragali, 7-13 parts of poria cocos, 1-7 parts of semen euryales, 1-7 parts of radish seed, 2-8 parts of rhizoma atractylodis macrocephalae, 0.5-2.5 parts of perillaseed, 0.5-2.5 parts of fructus arctii, 1-3 parts of microcrystalline cellulose, 0.03-0.06 part of lyophilized powder of royal jelly, 0.02-0.04 part of beta-cyclodextrine, 8-12 parts of starch, 0.001-0.003 part of isorhamnetin, 0.01-0.03 part of xylitol, 0.01-0.03 part of mannitol, 0.01-0.03 part of hydroxymethyl cellulose and 0.01-0.03 part of magnesium stearate. The rhizoma dioscoreae-radix astragali-poria cocos chewable tablets disclosed by the invention have the functions of reinforcing healthy qi and eliminating pathogen and enhancing immunity, and are suitable for obstructive pulmonary emphysema with symptoms such as cough with copious phlegm, shortness of breath, worse shortness of breath in labor and frequent chest distress and relatively severe shortness of breath in winter.

Description

A kind of Chinese yam Radix Astragali Poria cocos chewable tablets and preparation method
Technical field
The invention belongs to nutritional health food field, be specially a kind of Chinese yam Radix Astragali Poria cocos chewable tablets and preparation method.
Background technology
Modern coughs, phlegm is many, and the traditional Chinese medical science thinks that genus lung heat person is in the majority.Lung heat has from perception, or heat-transmission two kinds of catching cold.Performance cough, cough up phlegm and pant, tell yellow phlegm, thickness not easily brings up, have a fever, have a sore throat, dysphoria with smothery sensation thirsty, uncomfortable in chest, red tongue with yellowish fur, large and bounding pulse or sliding number etc.That causes above " lung heat " coughs, phlegm, to breathe heavily, and when going outer heresy to be main, auxiliary dispelling wind, cough-relieving, reducing phlegm, relievings asthma.But be difficult at present find a kind of Western medicine, above-mentioned comprehensive function can be had simultaneously.Lung-clearing anti-inflammatory ball can be declared logical, again can clearly in heat, to coughing, phlegm, breathe heavily evident in efficacy.Pneumonia, pulmonary heart disease etc. that the infection of the upper respiratory tract, acute bronchitis, AECB, Bronchopneumonia, lobar pneumonia, viral pneumonia and other reason cause, all can use lung-clearing anti-inflammatory ball, " phlegm coming from spleen; lung is the device of storage phlegm ", the generation of phlegm is mainly dirty relevant with lung, spleen two.The main breathing of lung, regulates discrepancy and the lifting of gas.When perverse trend invasion and attack lung, the body fluid in lung is easily caused to be condensed into phlegm.The spleen has the function to transport and transform nutrients, namely digests and transport nutriment to each internal organs.If damp evil invades human body, or worry beyond measure, overstrain and eating and drinking without temperance, can the impairment of the spleen and make it lose transportation capabilities, cause retention of water-damp in the body to condense into phlegm, and cause uncomfortable.
Summary of the invention
For above-mentioned situation, for above-mentioned situation, technical problem solved by the invention is to provide a kind ofly has strengthening vital QI to eliminate pathogenic factors, the Chinese yam Radix Astragali Poria cocos chewable tablets of develop immunitypty and preparation method, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of Chinese yam Radix Astragali Poria cocos chewable tablets, comprises following parts by weight ingredient: Chinese yam 7-13 part, Radix Astragali 7-13 part, Poria cocos 7-13 part, Gorgon fruit 1-7 part, radish seed 1-7 part, bighead atractylodes rhizome 2-8 part, perillaseed 0.5-2.5 part, great burdock achene 0.5-2.5 part, microcrystalline cellulose 1-3 part, royal jelly freeze-dried powder 0.03-0.06 part, cycloheptaamylose 0.02-0.04 part, starch 8-12 part, Isorhamnetin 0.001-0.003 part, xylitol 0.01-0.03 part, sweet mellow wine 0.01-0.03 part, CMC 0.01-0.03 part, dolomol 0.01-0.03 part.
As preferably, described a kind of Chinese yam Radix Astragali Poria cocos chewable tablets, comprises following parts by weight ingredient: Chinese yam 10 parts, the Radix Astragali 10 parts, 10 parts, Poria cocos, Gorgon fruit 4 parts, radish seed 4 parts, the bighead atractylodes rhizome 5 parts, perillaseed 1.5 parts, great burdock achene 1.5 parts, microcrystalline cellulose 2 parts, royal jelly freeze-dried powder 0.045 part, cycloheptaamylose 0.03 part, starch 10 parts, Isorhamnetin 0.002 part, xylitol 0.02 part, 0.02 part, sweet mellow wine, CMC 0.02 part, dolomol 0.02 part.
A preparation method for Chinese yam Radix Astragali Poria cocos chewable tablets, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling, cleans up, with 0.2% vitamin C aqueous solution soaking 7-15 minute, take out within the scope of 50-55 DEG C through 8-10 hour, to moisture is 5-12%, Chinese yam high speed disintegrator after oven dry is pulverized, cross 60-120 mesh sieve, then the Chinese yam ultramicro grinding will pulverized, regulate classifying turbine frequency to be 30-40Hz, collection cut size is less than 300-500 object Chinese yam Ultramicro-powder, for subsequent use;
(2) get the raw material Radix Astragali, Poria cocos, Gorgon fruit, radish seed, the bighead atractylodes rhizome, perillaseed, great burdock achene clean, add quality times 3-6 times of water heating and decoct 1-3 hour, decoct 2-3 time, medical filtration, by filter after liquid Vacuum Concentration to liquid weight be the 5-20% of inventory, filter, obtain mixed concentrated liquid, for subsequent use;
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) mixed concentrated liquid in the Chinese yam Ultramicro-powder in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again above-mentioned mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, beta-schardinger dextrin-, Isorhamnetin is added to above-mentioned Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 85%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains Chinese yam Radix Astragali Poria cocos chewable tablets.
Get fresh Chinese yam in described step (1) to clean, peeling, clean up, by 0.2% vitamin C aqueous solution soaking 15 minutes, take out within the scope of 50 DEG C through 10 hours, be 5% to moisture, Chinese yam high speed disintegrator after oven dry is pulverized, crosses 120 mesh sieves, the Chinese yam ultramicro grinding then will pulverized, regulate classifying turbine frequency to be 30-40Hz, collection cut size is less than 500 object Chinese yam Ultramicro-powders.
Described step (2) gets the raw material Radix Astragali, Poria cocos, Gorgon fruit, radish seed, the bighead atractylodes rhizome, perillaseed, great burdock achene are cleaned, and adds quality doubly 4 times of water heating decoctions 1 hour, decocts 3 times, medical filtration, by filter after liquid Vacuum Concentration to liquid weight be 20% of inventory, filter, obtain mixed concentrated liquid.
The every sheet of described chewable tablets is 0.6g-3.5g.
In sum, beneficial effect of the present invention:
The present invention has strengthening vital QI to eliminate pathogenic factors, develop immunitypty.Be applicable to cloudy plug property pulmonary emphysema, disease sees coughing with a lot of sputum, out of breath, out of breathly during work increases the weight of, and often feels uncomfortable in chest, out of breath more acute etc. winter.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A kind of Chinese yam Radix Astragali Poria cocos chewable tablets, comprises following parts by weight ingredient: Chinese yam 7 parts, the Radix Astragali 7 parts, 7 parts, Poria cocos, Gorgon fruit 1 part, radish seed 1 part, the bighead atractylodes rhizome 2 parts, perillaseed 0.5 part, great burdock achene 0.5 part, microcrystalline cellulose 1 part, royal jelly freeze-dried powder 0.03 part, cycloheptaamylose 0.02 part, starch 8 parts, Isorhamnetin 0.001 part, xylitol 0.01 part, 0.01 part, sweet mellow wine, CMC 0.01 part, dolomol 0.01 part.
A preparation method for Chinese yam Radix Astragali Poria cocos chewable tablets, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling, cleans up, with 0.2% vitamin C aqueous solution soaking 7-15 minute, take out within the scope of 50-55 DEG C through 8-10 hour, to moisture is 5-12%, Chinese yam high speed disintegrator after oven dry is pulverized, cross 60-120 mesh sieve, then the Chinese yam ultramicro grinding will pulverized, regulate classifying turbine frequency to be 30-40Hz, collection cut size is less than 300-500 object Chinese yam Ultramicro-powder, for subsequent use;
(2) get the raw material Radix Astragali, Poria cocos, Gorgon fruit, radish seed, the bighead atractylodes rhizome, perillaseed, great burdock achene clean, add quality times 3-6 times of water heating and decoct 1-3 hour, decoct 2-3 time, medical filtration, by filter after liquid Vacuum Concentration to liquid weight be the 5-20% of inventory, filter, obtain mixed concentrated liquid, for subsequent use;
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) mixed concentrated liquid in the Chinese yam Ultramicro-powder in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again above-mentioned mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, beta-schardinger dextrin-, Isorhamnetin is added to above-mentioned Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 85%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains Chinese yam Radix Astragali Poria cocos chewable tablets.
Embodiment 2
A kind of Chinese yam Radix Astragali Poria cocos chewable tablets, comprises following parts by weight ingredient: Chinese yam 10 parts, the Radix Astragali 10 parts, 10 parts, Poria cocos, Gorgon fruit 4 parts, radish seed 4 parts, the bighead atractylodes rhizome 5 parts, perillaseed 1.5 parts, great burdock achene 1.5 parts, microcrystalline cellulose 2 parts, royal jelly freeze-dried powder 0.045 part, cycloheptaamylose 0.03 part, starch 10 parts, Isorhamnetin 0.002 part, xylitol 0.02 part, 0.02 part, sweet mellow wine, CMC 0.02 part, dolomol 0.02 part.
A preparation method for Chinese yam Radix Astragali Poria cocos chewable tablets, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling, cleans up, with 0.2% vitamin C aqueous solution soaking 7-15 minute, take out within the scope of 50-55 DEG C through 8-10 hour, to moisture is 5-12%, Chinese yam high speed disintegrator after oven dry is pulverized, cross 60-120 mesh sieve, then the Chinese yam ultramicro grinding will pulverized, regulate classifying turbine frequency to be 30-40Hz, collection cut size is less than 300-500 object Chinese yam Ultramicro-powder, for subsequent use;
(2) get the raw material Radix Astragali, Poria cocos, Gorgon fruit, radish seed, the bighead atractylodes rhizome, perillaseed, great burdock achene clean, add quality times 3-6 times of water heating and decoct 1-3 hour, decoct 2-3 time, medical filtration, by filter after liquid Vacuum Concentration to liquid weight be the 5-20% of inventory, filter, obtain mixed concentrated liquid, for subsequent use;
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) mixed concentrated liquid in the Chinese yam Ultramicro-powder in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again above-mentioned mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, beta-schardinger dextrin-, Isorhamnetin is added to above-mentioned Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 85%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains Chinese yam Radix Astragali Poria cocos chewable tablets.
Embodiment 3
A kind of Chinese yam Radix Astragali Poria cocos chewable tablets, comprises following parts by weight ingredient: Chinese yam 13 parts, the Radix Astragali 13 parts, 13 parts, Poria cocos, Gorgon fruit 7 parts, radish seed 7 parts, the bighead atractylodes rhizome 8 parts, perillaseed 2.5 parts, great burdock achene 2.5 parts, microcrystalline cellulose 3 parts, royal jelly freeze-dried powder 0.06 part, cycloheptaamylose 0.04 part, starch 12 parts, Isorhamnetin 0.003 part, xylitol 0.03 part, 0.03 part, sweet mellow wine, CMC 0.03 part, dolomol 0.03 part.
A preparation method for Chinese yam Radix Astragali Poria cocos chewable tablets, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling, cleans up, with 0.2% vitamin C aqueous solution soaking 7-15 minute, take out within the scope of 50-55 DEG C through 8-10 hour, to moisture is 5-12%, Chinese yam high speed disintegrator after oven dry is pulverized, cross 60-120 mesh sieve, then the Chinese yam ultramicro grinding will pulverized, regulate classifying turbine frequency to be 30-40Hz, collection cut size is less than 300-500 object Chinese yam Ultramicro-powder, for subsequent use;
(2) get the raw material Radix Astragali, Poria cocos, Gorgon fruit, radish seed, the bighead atractylodes rhizome, perillaseed, great burdock achene clean, add quality times 3-6 times of water heating and decoct 1-3 hour, decoct 2-3 time, medical filtration, by filter after liquid Vacuum Concentration to liquid weight be the 5-20% of inventory, filter, obtain mixed concentrated liquid, for subsequent use;
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) mixed concentrated liquid in the Chinese yam Ultramicro-powder in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again above-mentioned mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, beta-schardinger dextrin-, Isorhamnetin is added to above-mentioned Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 85%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains Chinese yam Radix Astragali Poria cocos chewable tablets.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or essential characteristic, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.

Claims (1)

1. a Chinese yam Radix Astragali Poria cocos chewable tablets, is characterized in that: be made up of following raw material: Chinese yam 10 parts, the Radix Astragali 10 parts, 10 parts, Poria cocos, Gorgon fruit 4 parts, radish seed 4 parts, the bighead atractylodes rhizome 5 parts, perillaseed 1.5 parts, great burdock achene 1.5 parts, microcrystalline cellulose 2 parts, royal jelly freeze-dried powder 0.045 part, cycloheptaamylose 0.03 part, starch 10 parts, Isorhamnetin 0.002 part, xylitol 0.02 part, 0.02 part, sweet mellow wine, CMC 0.02 part, dolomol 0.02 part; Its preparation method is:
(1) get fresh Chinese yam to clean, peeling, cleaned up, by 0.2% vitamin C aqueous solution soaking 15 minutes, take out within the scope of 50 DEG C through 10 hours, be 5% to moisture, Chinese yam high speed disintegrator after oven dry pulverized, crosses 120 mesh sieves, then the Chinese yam ultramicro grinding will pulverized, regulate classifying turbine frequency to be 30-40Hz, collection cut size is less than 500 object Chinese yam Ultramicro-powders, for subsequent use;
(2) get the raw material Radix Astragali, Poria cocos, Gorgon fruit, radish seed, the bighead atractylodes rhizome, perillaseed, great burdock achene clean, add the water heating decoction 1 hour of quality 4 times amount, decoct 3 times, medical filtration, is 20% of inventory by liquid Vacuum Concentration to the liquid weight after filtering, filters, obtain mixed concentrated liquid, for subsequent use;
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) mixed concentrated liquid in the Chinese yam Ultramicro-powder in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, cycloheptaamylose, Isorhamnetin is added to Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after pulverizing in step (3), xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 85%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains Chinese yam Radix Astragali Poria cocos chewable tablets.
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CN106727882A (en) * 2016-11-30 2017-05-31 四川旭阳药业有限责任公司 The method that microwave sterilization is carried out to the Radix Astragali
CN108056461B (en) * 2017-12-10 2021-04-30 牡丹江师范学院 Black fungus chewable tablet with intestine moistening function and preparation method thereof
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